Compounds > 3-amino-1-phenylbutane
Page last updated: 2024-12-06

3-amino-1-phenylbutane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-amino-1-phenylbutane: urinary metabolite of labetalol; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID31160
SCHEMBL ID1280
MeSH IDM0162115

Synonyms (66)

Synonym
nsc 115524
benzenepropanamine, alpha-methyl-
1-phenyl-3-amino-butan [german]
brn 2413110
propylamine, alpha-methyl-gamma-phenyl-
einecs 244-942-2
alpha-methyl-gamma-phenyl-n-propylamin [german]
alpha-methyl-gamma-phenyl-n-propylamine
alpha-methylbenzenepropanamine
4-phenyl-2-aminobutane
nsc115524
.alpha.-methylbenzenepropanamine
benzenepropanamine, .alpha.-methyl-
nsc-115524
1-methyl-3-phenylpropylamine
propylamine, 1-methyl-3-phenyl-
1-phenyl-3-aminobutane
3-amino-1-phenylbutane
22374-89-6
1-methyl-3-phenylpropylamine, 98%
4-phenyl-2-butylamine
A0999
22148-77-2
wecuigdewbnqjj-uhfffaoysa-
inchi=1/c10h15n/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9h,7-8,11h2,1h3
4-phenylbutan-2-amine
AKOS000119752
2-amino-4-phenylbutane
A815973
[(1s)-1-methyl-3-phenyl-propyl]ammonium
A816167
unii-326655w66z
alpha-methyl-gamma-phenyl-n-propylamin
1-phenyl-3-amino-butan
326655w66z ,
FT-0608062
FT-0605036
FT-0605241
FT-0604461
PS-5334
1-methy-3-phenylpropylamine
1-phenyl-3-butylamine
1-methyl-3-phenyl-propylamine
1-methyl 3-phenyl-propylamine
AKOS016051338
SCHEMBL1280
W-107477
3-phenyl-1-methylpropylamine
propylamine, .alpha.-methyl-.gamma.-phenyl-
.alpha.-methyl-.gamma.-phenyl-n-propylamine
4-phenyl-2-butanamine
(3-aminobutyl)benzene
F2190-0401
mfcd00008090
AC-8354
(r)-alpha-methylbenzenepropanamine
DTXSID60871334
STL193993
AMY40882
Q27256149
benzenepropanamine, -methyl-
SB47247
methyl-(3-phenylpropyl)-
CS-0022291
EN300-20027
Z104476462

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" Pharmacokinetic analysis shows the apparent elimination half-life of the metabolite to be 13."( Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep.
Abbott, FS; Axelson, JE; Doroudian, A; Hall, C; Kwan, E; Rurak, DW; Yeleswaram, K, )		0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (3)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.19 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index17.79 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.19)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (20.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
labetalol
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.. labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.. 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.		7.6730benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound
ConditionIndicatedRelationship StrengthStudiesTrials
Blood Pressure, High
[description not available]		01.9710
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.		01.9710