juglone has been researched along with Hypertension in 2 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice treated with juglone for 2 weeks, as well as Pin1 knockout mice, exhibited increased aortic endothelial NO synthase serine 116 phosphorylation, endothelial dysfunction, and hypertension." | 1.37 | Pin1 deficiency causes endothelial dysfunction and hypertension. ( Chatterjee, P; Chiasson, VL; Mitchell, BM; Munshi, N; Young, KJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, T | 1 |
| Khan, T | 1 |
| Shah, AJ | 1 |
| Chiasson, VL | 1 |
| Munshi, N | 1 |
| Chatterjee, P | 1 |
| Young, KJ | 1 |
| Mitchell, BM | 1 |
2 other studies available for juglone and Hypertension
| Article | Year |
|---|---|
Juglone as antihypertensive agent acts through multiple vascular mechanisms.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Endothelium, Vascular; Hypertension; Male; Naphtho | 2020 |
Pin1 deficiency causes endothelial dysfunction and hypertension.
Topics: Amino Acid Substitution; Animals; Aorta; Binding Sites; Blood Pressure; Cells, Cultured; Endothelium | 2011 |