Page last updated: 2024-09-02

benzamil and Hypertension

benzamil has been researched along with Hypertension in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (30.00)18.2507
2000's9 (45.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersen, H; Hansen, PBL; Jacobsen, IA; Jensen, BL; Jürgensen, JF; Oxlund, CS; Peluso, AA; Staehr, M; Svenningsen, P; Vanhoutte, PM; Ydegaard, R1
Cowley, AW; Ilatovskaya, DV; Levchenko, V; Lombard, JH; Mattson, DL; Mori, T; O'Connor, PM; Palygin, O; Pavlov, TS; Sorokin, A; Staruschenko, A1
Carretero, OA; D'Ambrosio, MA; Garvin, JL; Ren, Y; Wang, H1
Gabor, A; Leenen, FH1
Amin, MS; Leenen, FH; Reza, E; Wang, H1
Aaronson, PI; Loutzenhiser, R1
Amin, MS; Leenen, FH; Van Huysse, JW; Yang, B1
Auberson, M; Hoffmann-Pochon, N; Kellenberger, S; Schild, L; Vandewalle, A1
Leenen, FH; Wang, H1
Huang, BS; Leenen, FH; Wang, H1
Hagiwara, Y; Kubo, T1
Butler, AA; Cone, RD; Humphreys, MH; Ni, XP1
Abrams, JM; Osborn, JW1
Gomez-Sanchez, CE; Gomez-Sanchez, EP2
Gómez Sánchez, EP1
Nanbu, A; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M1
Betz, AL; Ennis, SR; Keep, RF; Shakui, P; Si, X1
Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M1
Hawk, CT; Schafer, JA1

Reviews

1 review(s) available for benzamil and Hypertension

ArticleYear
A role for benzamil-sensitive proteins of the central nervous system in the pathogenesis of salt-dependent hypertension.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:5-6

    Topics: Amiloride; Central Nervous System; Humans; Hypertension; Sodium Channel Blockers; Sodium Chloride

2008

Trials

1 trial(s) available for benzamil and Hypertension

ArticleYear
The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice.
    Acta physiologica (Oxford, England), 2019, Volume: 225, Issue:1

    Topics: Acid Sensing Ion Channel Blockers; Amiloride; Animals; Blood Pressure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelial Cells; Epithelial Sodium Channels; Gene Expression Regulation; Humans; Hypertension; Mice; Mice, Knockout; Nitric Oxide Synthase Type III

2019

Other Studies

18 other study(ies) available for benzamil and Hypertension

ArticleYear
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.
    Journal of the American Society of Nephrology : JASN, 2013, Volume: 24, Issue:7

    Topics: Amiloride; Animals; Blood Pressure; Disease Models, Animal; Epidermal Growth Factor; Epithelial Sodium Channels; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary

2013
Connecting tubule glomerular feedback in hypertension.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:4

    Topics: Amiloride; Animals; Blood Pressure; Hypertension; Kidney Glomerulus; Nephrons; Rats; Rats, Inbred Dahl; Vasoconstriction

2013
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone

2009
Sodium transport in the choroid plexus and salt-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4

    Topics: Amiloride; Animals; Biological Transport; Choroid Plexus; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Male; Ouabain; Rats; Rats, Inbred Dahl; Rats, Wistar; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary

2009
Role of epithelial sodium channels in the renal myogenic response?
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2

    Topics: Amiloride; Humans; Hypertension; Muscle, Smooth, Vascular; Renal Artery; Sodium Channel Blockers; Sodium Channels; Vasoconstriction

2010
Salt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brain.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Amiloride; Animals; Blood Pressure; Brain; Disease Models, Animal; Endosomal Sorting Complexes Required for Transport; Epithelial Sodium Channels; Female; Heart Rate; Hypertension; Liddle Syndrome; Male; Mice; Mice, Knockout; Nedd4 Ubiquitin Protein Ligases; Sodium; Sodium Chloride, Dietary; Ubiquitin-Protein Ligases

2012
Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:3

    Topics: Aldosterone; Amiloride; Animals; Cell Line; Electric Conductivity; Epithelial Cells; Gene Expression; Humans; Hypertension; Mice; Mutation; Sodium Channels; Syndrome; Vasopressins

2003
Brain sodium channels and central sodium-induced increases in brain ouabain-like compound and blood pressure.
    Journal of hypertension, 2003, Volume: 21, Issue:8

    Topics: Amiloride; Animals; Blood Pressure; Cardenolides; Digoxin; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Hypothalamus; Injections, Intraventricular; Male; Pituitary Gland; Rats; Rats, Wistar; Saponins; Sodium; Sodium Channels

2003
Brain sodium channels and ouabainlike compounds mediate central aldosterone-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6

    Topics: Aldosterone; Amiloride; Animals; Blood Pressure; Brain Chemistry; Cardenolides; Digoxin; Heart Rate; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Wistar; Saponins; Sodium; Sodium Channels; Sympathetic Nervous System

2003
Enhanced central hypertonic saline-induced activation of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive and Dahl S rats.
    Brain research bulletin, 2006, Jan-30, Volume: 68, Issue:5

    Topics: Action Potentials; Amiloride; Angiotensin II; Animals; Anterior Hypothalamic Nucleus; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Hypertension; Male; Neurons; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Saline Solution, Hypertonic; Sodium; Vasoconstrictor Agents

2006
Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones.
    Journal of hypertension, 2006, Volume: 24, Issue:11

    Topics: alpha-MSH; Amiloride; Animals; Blood Pressure; Dose-Response Relationship, Drug; gamma-MSH; Heart Rate; Hypertension; Mice; Mice, Knockout; Models, Animal; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4; Sodium Channel Blockers; Sympatholytics

2006
Effect of central infusion of benzamil on Dahl S rat hypertension.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Amiloride; Animals; Brain; Drug Resistance; Hypertension; Injections, Intraventricular; Rats; Rats, Inbred Strains; Sodium Chloride

1995
Hypertension and the mineralocorticoid receptor in the brain.
    Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746

    Topics: Adrenalectomy; Aldosterone; Amiloride; Animals; Blood Pressure; Brain; Cerebral Ventricles; Hippocampus; Hypertension; Infusions, Parenteral; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Spironolactone

1994
Effect of central amiloride infusion on mineralocorticoid hypertension.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 1

    Topics: Aldosterone; Amiloride; Animals; Brain; Carbenoxolone; Diet; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Male; Mineralocorticoids; Rats; Rats, Sprague-Dawley

1994
Benzamil blockade of brain Na+ channels averts Na(+)-induced hypertension in rats.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Amiloride; Animals; Arginine Vasopressin; Blood Pressure; Endothelin-1; Heart Rate; Hypertension; Injections, Intraventricular; Male; Natriuresis; Rats; Rats, Wistar; Saline Solution, Hypertonic; Sodium Channel Blockers

1998
Effect of amiloride analogs on DOCA-salt-induced hypertension in rats.
    The American journal of physiology, 1999, Volume: 276, Issue:6

    Topics: Amiloride; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride

1999
Role of FMRFamide-activated brain sodium channel in salt-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Amiloride; Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Brain Chemistry; DNA Primers; FMRFamide; Ganglia, Sympathetic; Gene Expression; Heart Rate; Hypertension; Injections, Intraventricular; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Channels; Sodium Chloride, Dietary

2000
Effects of AVP and deoxycorticosterone on Na+ and water transport in the Dahl salt-sensitive rat CCD.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2

    Topics: Absorption; Amiloride; Animals; Arginine Vasopressin; Body Water; Cell Membrane; Desoxycorticosterone; Drug Synergism; Hypertension; Kidney Tubules, Collecting; Kinetics; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Sodium; Sodium Channels; Sodium, Dietary

1991