Page last updated: 2024-08-07 13:22:08
Corticosteroid 11-beta-dehydrogenase isozyme 2
An 11-beta-hydroxysteroid dehydrogenase type 2 that is encoded in the genome of mouse. [OMA:P51661, PRO:DNx]
Synonyms
EC 1.1.1.-;
11-beta-hydroxysteroid dehydrogenase type 2;
11-DH2;
11-beta-HSD2;
NAD-dependent 11-beta-hydroxysteroid dehydrogenase
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| kaurenoic acid | Mus musculus (house mouse) | IC50 | 500.0000 | 1 | 1 |
| carbenoxolone | Mus musculus (house mouse) | IC50 | 0.1440 | 2 | 2 |
| 3-(1-adamantyl)-6,7,8,9-tetrahydro-5h-(1,2,4)triazolo(4,3-a)azepine | Mus musculus (house mouse) | IC50 | 10.0000 | 3 | 3 |
| mk-0916 | Mus musculus (house mouse) | IC50 | 4.0000 | 1 | 2 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| carbenoxolone | Mus musculus (house mouse) | EC50 | 0.0820 | 1 | 1 |