8-phenyltheophylline and Hypertension studies

8-phenyltheophylline and Hypertension

8-phenyltheophylline: purinergic P1 receptor antagonist

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

Excerpt	Relevance	Reference
"8-Phenyltheophylline abolished hypoxia-induced bradycardia and hypertension and produced a nearly 5-fold greater rise in fetal plasma concentrations of corticotropin and approximately a 3-fold greater increase in plasma cortisol levels."	3.70	Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep. ( Chau, A; Koos, BJ; Rose, JC, 1999)

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (25.00)	18.7374
1990's	3 (75.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (25.00)

18.7374

1990's

3 (75.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Chau, A	2
Rose, JC	1
Koos, BJ	2
Koga, T	1
Takata, Y	1
Kobayashi, K	1
Fujii, K	1
Nagao, T	1
Fujishima, M	1
Illes, P	1
Rickmann, H	1
Brod, I	1
Bucher, B	1
Stoclet, JC	1

Studies

Chau, A

Rose, JC

Koos, BJ

Koga, T

Takata, Y

Kobayashi, K

Fujii, K

Nagao, T

Fujishima, M

Illes, P

Rickmann, H

Brod, I

Bucher, B

Stoclet, JC

Other Studies

4 other studies available for 8-phenyltheophylline and Hypertension

Article	Year
Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep. American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:5 Topics: Adenosine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Bradycardia; Female; Fetal Blood; F	1999
Metabolic and cardiorespiratory responses to hypoxia in fetal sheep: adenosine receptor blockade. The American journal of physiology, 1999, Volume: 276, Issue:6 Topics: Acids; Adenosine; Animals; Cerebral Cortex; Fetal Hypoxia; Fetus; Heart; Heart Rate; Hypertension; I	1999
Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3 Topics: Adenosine Triphosphate; Aging; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascul	1992
Subsensitivity of presynaptic adenosine A1-receptors in caudal arteries of spontaneously hypertensive rats. European journal of pharmacology, 1989, Dec-19, Volume: 174, Issue:2-3 Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Elect	1989

Article

Year

Adenosine modulates corticotropin and cortisol release during hypoxia in fetal sheep.

American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:5

Topics: Adenosine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Bradycardia; Female; Fetal Blood; F

1999

Metabolic and cardiorespiratory responses to hypoxia in fetal sheep: adenosine receptor blockade.

The American journal of physiology, 1999, Volume: 276, Issue:6

Topics: Acids; Adenosine; Animals; Cerebral Cortex; Fetal Hypoxia; Fetus; Heart; Heart Rate; Hypertension; I

1999

Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3

Topics: Adenosine Triphosphate; Aging; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascul

1992

Subsensitivity of presynaptic adenosine A1-receptors in caudal arteries of spontaneously hypertensive rats.

European journal of pharmacology, 1989, Dec-19, Volume: 174, Issue:2-3

Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Elect

1989