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8-hydroxy-2-(di-n-propylamino)tetralin and Hypertension

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Hypertension in 9 studies

8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Treatment with amphetamine caused significant disruption of prepulse inhibition in SHR and WKY rats, but not SD rats."1.32Prepulse inhibition of acoustic startle in spontaneously hypertensive rats. ( van den Buuse, M, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's7 (77.78)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van den Buuse, M3
Buisson-Defferier, S2
Hibert, M1
Liu, BJ1
Qiu, XC1
Lal, KJ1
Dakshinamurti, K1
Evenden, J1
Meyerson, B1
Huguet, F1
Brisac, AM1
Bouhelal, R1
Loubatières-Mariani, MM1
Mir, AK1
Docherty, JR1

Other Studies

9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Hypertension

ArticleYear
Prepulse inhibition of acoustic startle in spontaneously hypertensive rats.
    Behavioural brain research, 2004, Oct-05, Volume: 154, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic Agents; Amphetamine; Analys

2004
Differential cardiovascular effects of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), flesinoxan, 5-methyl-urapidil and MDL 75,608A in conscious spontaneously hypertensive rats.
    Fundamental & clinical pharmacology, 1993, Volume: 7, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cardi

1993
[The characterization of 5-HT1A receptor in the central nervous system of the spontaneously hypertensive rats].
    Sheng li xue bao : [Acta physiologica Sinica], 1994, Volume: 46, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Hippocampus; Hypertension; Hypothalamus; Rad

1994
Hypotensive action of 5-HT receptor agonists in the vitamin B6-deficient hypertensive rat.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cerebral C

1993
The behavior of spontaneously hypertensive and Wistar Kyoto rats under a paced fixed consecutive number schedule of reinforcement.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Chlordiazepoxide; Conditioning, Opera

1999
Cardiovascular effects of the 5-HT1A receptor ligand, MDL 73005EF, in conscious spontaneously hypertensive rats.
    European journal of pharmacology, 1992, Nov-17, Volume: 223, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agen

1992
Central 5HT1A-receptor binding in normotensive and spontaneously hypertensive rats.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hypertension; Male; Medulla Oblongata; Rats; Rats,

1991
Investigation of the mechanism(s) of 8-OH-DPAT-mediated inhibition of plasma insulin in spontaneously hypertensive rats.
    British journal of pharmacology, 1990, Volume: 100, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Glucose; Blood Pressure; Clonidin

1990
An investigation of the effects of intravenous injection of the 5-hydroxytryptamine 2 receptor antagonists ketanserin and LY 53857 on blood pressure in anesthetized spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Pressure; Ergolines; Heart Rate;

1989