Page last updated: 2024-11-11

estradiol-drospirenone combination

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

estradiol-drospirenone combination: consists of 17beta-estradiol and drospirenone; used to treat menopause [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9874151
SCHEMBL ID8459807
MeSH IDM0491520

Synonyms (10)

Synonym
estradiol-drospirenone combination
drospirenone and estradiol
eliq
350818-73-4
bay 86-4891
estradiol / drospirenone
drospirenone / estradiol
SCHEMBL8459807
DTXSID30188582
(1r,2r,4r,10r,11s,14s,15s,16s,18s,19s)-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadec-5-ene-15,5'-oxolane]-2',7-dione;(8r,9s,13s,14s,17s)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Research Excerpts

Compound-Compound Interactions

ExcerptReferenceRelevance
" For postmenopausal HRT, 2 mg drospirenone was combined with 1 mg 17beta-estradiol (Angeliq, Schering AG, Berlin, Germany) for continuous treatment."( Drospirenone in combination with estrogens: for contraception and hormone replacement therapy.
Oelkers, WH, 2005
)
0.33
"0 mg estradiol in combination with different doses of drospirenone for the treatment of menopausal hot flushes."( 0.5 vs. 1.0 mg estradiol in combination with drospirenone for the treatment of hot flushes.
Endrikat, J; Gerlinger, C; Gude, K; Schaefers, M; Schmelter, T, 2015
)
0.42
"5 and 1 mg in combination with different drospirenone doses."( 0.5 vs. 1.0 mg estradiol in combination with drospirenone for the treatment of hot flushes.
Endrikat, J; Gerlinger, C; Gude, K; Schaefers, M; Schmelter, T, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (50.00)29.6817
2010's9 (40.91)24.3611
2020's2 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.29 (24.57)
Research Supply Index3.50 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index44.23 (26.88)
Search Engine Supply Index2.11 (0.95)

This Compound (33.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials9 (39.13%)5.53%
Reviews8 (34.78%)6.00%
Case Studies1 (4.35%)4.05%
Observational0 (0.00%)0.25%
Other5 (21.74%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]