7-nitroindazole has been researched along with Hypertension in 13 studies
7-nitroindazole: an inhibitor of nitric oxide synthase; exhibits anti-nociceptive activity without increasing blood pressure
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Blood pressure and renal excretion were measured in adulthood, under different sodium conditions, and before and after chronic administration of either N(G)-nitro-l-arginine methyl ester (l-NAME) or l-arginine." | 1.35 | Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals. ( Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N, 2008) |
| "Since chronic hypertension has been associated with impaired endothelial function, we designed a study to find out whether hypercapnic cerebral blood flow and its nitric oxide- and prostaglandin-sensitive component is reduced in spontaneously hypertensive rats (SHR) compared with normotensive controls." | 1.30 | Hypercapnic cerebral blood flow in spontaneously hypertensive rats. ( Casadei, B; Heinert, G; Paterson, DJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dovinová, I | 1 |
| Hrabárová, E | 1 |
| Jansen, E | 1 |
| Kvandová, M | 1 |
| Majzúnová, M | 1 |
| Berenyiová, A | 1 |
| Barančík, M | 1 |
| Kristek, F | 2 |
| Drobna, M | 1 |
| Cacanyiova, S | 2 |
| Lee, YH | 1 |
| Tsai, MC | 1 |
| Li, TL | 1 |
| Dai, YW | 1 |
| Huang, SC | 1 |
| Hwang, LL | 1 |
| Malekova, M | 1 |
| Ondrias, K | 1 |
| Huang, CF | 1 |
| Hsu, CN | 1 |
| Chien, SJ | 1 |
| Lin, YJ | 1 |
| Huang, LT | 1 |
| Tain, YL | 1 |
| Xavier, FE | 1 |
| Salaices, M | 1 |
| Márquez-Rodas, I | 1 |
| Alonso, MJ | 1 |
| Rossoni, LV | 1 |
| Vassallo, DV | 1 |
| Balfagón, G | 1 |
| Calderón-Cortés, E | 1 |
| Clemente-Guerrero, M | 1 |
| Sierra-Campos, E | 1 |
| Cortés-Rojo, C | 1 |
| Gaona-Zamudio, FJ | 1 |
| Villalobos-Molina, R | 1 |
| Saavedra-Molina, A | 1 |
| Carlström, M | 1 |
| Brown, RD | 1 |
| Edlund, J | 1 |
| Sällström, J | 1 |
| Larsson, E | 1 |
| Teerlink, T | 1 |
| Palm, F | 1 |
| Wåhlin, N | 1 |
| Persson, AE | 1 |
| Fouyas, IP | 1 |
| Kelly, PA | 1 |
| Ritchie, IM | 1 |
| Whittle, IR | 1 |
| Heinert, G | 1 |
| Casadei, B | 1 |
| Paterson, DJ | 1 |
| Tan, DY | 1 |
| Meng, S | 1 |
| Manning, RD | 1 |
| Welch, WJ | 1 |
| Tojo, A | 1 |
| Wilcox, CS | 1 |
| Wu, WC | 1 |
| Wang, Y | 1 |
| Su, CK | 1 |
| Chai, CY | 1 |
13 other studies available for 7-nitroindazole and Hypertension
| Article | Year |
|---|---|
ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; H | 2018 |
Different effects of 7-nitroindazole and L-NAME administered both individually and together on the cardiovascular system of the rat.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Carotid Arteries; Coronary Vessels; Disease | 2015 |
Spontaneously hypertensive rats have more orexin neurons in the hypothalamus and enhanced orexinergic input and orexin 2 receptor-associated nitric oxide signalling in the rostral ventrolateral medulla.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Hypothalamus; Indazoles; Male; Medulla Oblongata; | 2015 |
Effects of chronic neuronal nitric oxide-synthase inhibition on arterial function and structure in spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiomegaly; Enzyme Inhibitors; Heart; Hypertension; Inda | 2012 |
Aminoguanidine attenuates hypertension, whereas 7-nitroindazole exacerbates kidney damage in spontaneously hypertensive rats: the role of nitric oxide.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Citrulline; Guanidines; Hypertension; Indazoles; | 2013 |
Neurogenic nitric oxide release increases in mesenteric arteries from ouabain hypertensive rats.
Topics: Animals; Electric Stimulation; Enzyme Inhibitors; Hypertension; Indazoles; Male; Mesenteric Arteries | 2004 |
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxi | 2006 |
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephros | 2008 |
Cerebrovascular effects of nitric oxide manipulation in spontaneously hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autoradiography; Blood Pressure; Cereb | 1997 |
Hypercapnic cerebral blood flow in spontaneously hypertensive rats.
Topics: Animals; Blood Flow Velocity; Cerebral Cortex; Cerebrovascular Circulation; Enzyme Inhibitors; Hyper | 1998 |
Role of neuronal nitric oxide synthase in Dahl salt-sensitive hypertension.
Topics: Animals; Blood Pressure; Diet, Sodium-Restricted; Enzyme Inhibitors; Glomerular Filtration Rate; Hyp | 1999 |
Roles of NO and oxygen radicals in tubuloglomerular feedback in SHR.
Topics: Animals; Cyclic N-Oxides; Feedback; Hypertension; Indazoles; Kidney Glomerulus; Kidney Tubules; Male | 2000 |
The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats.
Topics: Animals; Blood Pressure; Bradycardia; Cats; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Ago | 2001 |