Page last updated: 2024-11-13

2,3',5',6-tetrahydroxy-trans-stilbene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

2,3',5',6-tetrahydroxy-trans-stilbene: a naturally occurring compound particularly found in the genus Gnetum, had a strong inhibitory effect on murine tyrosinase activity; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
GnetumgenusA plant genus of the family Gnetaceae, order Gnetales class Gnetopsida, division GNETOPHYTA. Members contain STILBENES and benzylisoquinoline alkaloids.[MeSH]Gnetaceae[no description available]

Cross-References

ID SourceID
PubMed CID45382232
SCHEMBL ID676425
SCHEMBL ID676426
MeSH IDM0453191

Synonyms (20)

Synonym
A841618
86361-55-9
2-[2-(3,5-dihydroxyphenyl)vinyl]benzene-1,3-diol
2,3',5',6-tetrahydroxy-trans-stilbene
G0371
gnetol
(e)-2-(3,5-dihydroxystyryl)benzene-1,3-diol
AKOS015915204
SCHEMBL676425
SCHEMBL676426
1,3-benzenediol, 2-[(1e)-2-(3,5-dihydroxyphenyl)ethenyl]-
AC-24226
AS-65738
5-[(1e)-2-(2,6-dihydroxyphenyl)ethenyl]benzene-1,3-diol
2-[(1e)-2-(3,5-dihydroxyphenyl)ethenyl]-1,3-benzenediol
2-[(e)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol
HY-126052
CS-0090331
mfcd12405548
C76801

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"Studies were undertaken to evaluate the bioavailability in rats and content analysis of gnetol in Gnetum gnemon products reported to contain gnetol and to examine the pharmacological properties of gnetol in in vitro models including anti-inflammatory/analgesic, antidiabetic, anti-adipogenesis, and anticancer activity."( Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs.
Akinwumi, BC; Anderson, HD; Davies, NM; Martinez, SE; Remsberg, CM; Sayre, CL; Takemoto, JK, 2015
)
0.42

Dosage Studied

ExcerptRelevanceReference
" Male Sprague-Dawley rats were cannulated and dosed either intravenously with gnetol (10 mg/kg) or orally (100 mg/kg)."( Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs.
Akinwumi, BC; Anderson, HD; Davies, NM; Martinez, SE; Remsberg, CM; Sayre, CL; Takemoto, JK, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's7 (63.64)24.3611
2020's3 (27.27)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]