Compounds > 2,3',5',6-tetrahydroxy-trans-stilbene
Page last updated: 2024-08-03 16:15:22
2,3',5',6-tetrahydroxy-trans-stilbene
Description
2,3',5',6-tetrahydroxy-trans-stilbene: a naturally occurring compound particularly found in the genus Gnetum, had a strong inhibitory effect on murine tyrosinase activity; structure in first source [MeSH]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 45382232 |
| SCHEMBL ID | 676425 |
| SCHEMBL ID | 676426 |
| MeSH ID | M0453191 |
Synonyms (20)
| Synonym |
|---|
| A841618 |
| 86361-55-9 |
| 2-[2-(3,5-dihydroxyphenyl)vinyl]benzene-1,3-diol |
| 2,3',5',6-tetrahydroxy-trans-stilbene |
| G0371 |
| gnetol |
| (e)-2-(3,5-dihydroxystyryl)benzene-1,3-diol |
| AKOS015915204 |
| SCHEMBL676425 |
| SCHEMBL676426 |
| 1,3-benzenediol, 2-[(1e)-2-(3,5-dihydroxyphenyl)ethenyl]- |
| AC-24226 |
| AS-65738 |
| 5-[(1e)-2-(2,6-dihydroxyphenyl)ethenyl]benzene-1,3-diol |
| 2-[(1e)-2-(3,5-dihydroxyphenyl)ethenyl]-1,3-benzenediol |
| 2-[(e)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol |
| HY-126052 |
| CS-0090331 |
| mfcd12405548 |
| C76801 |
Research
Studies (11)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (9.09%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (90.91%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|
| emodin | | trihydroxyanthraquinone | antineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor | 2018 | 2018 | 6.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| kojic acid | | 4-pyranones;
enol;
primary alcohol | Aspergillus metabolite;
EC 1.10.3.1 (catechol oxidase) inhibitor;
EC 1.10.3.2 (laccase) inhibitor;
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 1.4.3.3 (D-amino-acid oxidase) inhibitor;
NF-kappaB inhibitor;
skin lightening agent | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| glucose, (beta-d)-isomer | | D-glucopyranose | epitope;
mouse metabolite | 2018 | 2018 | 6.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| resveratrol | | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger | 2017 | 2022 | 5.5 | medium | 0 | 0 | 0 | 0 | 3 | 1 |
| rhapontin | | rhaponticin | angiogenesis inhibitor;
anti-allergic agent;
anti-inflammatory agent;
antilipemic drug;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
hypoglycemic agent;
neuroprotective agent;
plant metabolite | 2018 | 2018 | 6.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| stilbenes | | stilbene | | 2003 | 2022 | 8.1 | high | 0 | 0 | 0 | 1 | 8 | 2 |
| 3,3',4,5'-tetrahydroxystilbene | | catechols;
polyphenol;
resorcinols;
stilbenol | antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor | 2018 | 2018 | 6.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| trans-2,3',4,5'-tetrahydroxystilbene | | stilbenoid | | 2020 | 2022 | 3.0 | low | 0 | 0 | 0 | 0 | 1 | 1 |
| pterostilbene | | diether;
methoxybenzenes;
stilbenol | anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
neuroprotective agent;
neurotransmitter;
plant metabolite;
radical scavenger | 2017 | 2018 | 6.7 | medium | 0 | 0 | 0 | 0 | 3 | 0 |
| 2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside | | | | 2018 | 2018 | 6.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
Peripheral and Cerebral Resistance Arteries in the Spontaneously Hypertensive Heart Failure Rat: Effects of Stilbenoid Polyphenols.Molecules (Basel, Switzerland), , Feb-28, Volume: 22, Issue:3, 2017
Disparate Effects of Stilbenoid Polyphenols on Hypertrophic Cardiomyocytes In Vitro vs. in the Spontaneously Hypertensive Heart Failure Rat.Molecules (Basel, Switzerland), , Feb-01, Volume: 22, Issue:2, 2017
Bioavailability (2)
Dosage (1)