aminopropionitrile has been researched along with Hypertension in 24 studies
Aminopropionitrile: Reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 7.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| "Angiotensin II (AngII)-activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development." | 7.85 | Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm. ( Boyer, MJ; Cooper, HA; Eguchi, S; Forrester, SJ; Hashimoto, T; Kawai, T; Kobayashi, T; Kwok, HF; Obama, T; Preston, KJ; Rizzo, V; Scalia, R; Takayanagi, T; Tsuji, T, 2017) |
| " The model was established by administering angiotensin II (Ang II) and β-aminopropionitrile (BAPN), a lysyl oxidase inhibitor, to mice to induce hypertension and degeneration of the elastic lamina, which would eventually result in the onset of an aortic aneurysm." | 3.96 | Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice. ( Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y, 2020) |
| "Angiotensin II (AngII)-activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development." | 3.85 | Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm. ( Boyer, MJ; Cooper, HA; Eguchi, S; Forrester, SJ; Hashimoto, T; Kawai, T; Kobayashi, T; Kwok, HF; Obama, T; Preston, KJ; Rizzo, V; Scalia, R; Takayanagi, T; Tsuji, T, 2017) |
| "Saccular cerebral aneurysms were successfully induced in two monkeys treated with ligation of the common carotid artery, experimental hypertension, and beta-aminopropionitrile feeding." | 3.67 | Experimental induction of cerebral aneurysms in monkeys. ( Hashimoto, N; Hazama, F; Kang, Y; Kikuchi, H; Kim, C; Kojima, M, 1987) |
| "The effects of beta-aminopropionitrile (BAPN), an inhibitor of collagen maturation, have been examined in three models of hypertension in rats." | 3.66 | Effects of inhibitors of collagen maturation on hypertension in rats. ( Franklin, TJ; Loveday, BE; Morris, WP, 1982) |
| "The susceptibility to experimental cerebral aneurysm formation in arteries of the circle of Willis was studied in four strains of rats presenting different susceptibilities to the spontaneous rupture of the internal elastic lamina in extracerebral arteries: Brown-Norway (BN) > Wistar > Long-Evans (LE) > LOU." | 1.30 | Genetic susceptibility to experimental cerebral aneurysm formation in the rat. ( Coutard, M; Osborne-Pellegrin, M, 1997) |
| "Thus, in pressure-overloaded cardiac hypertrophy with coronary hypertension, coronary reserve seems to be determined by medial hypertrophy independently of collagen deposition, but collagen deposition plays an important role in the reversal of vasodilator reserve after relief of the overload." | 1.28 | Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy. ( Isoyama, S; Ito, N; Satoh, K; Takishima, T, 1992) |
| "beta-aminopropionitrile (BAPN), which is an inhibitor of the enzyme lysyl oxidase implicated in the synthesis of elastin, is able to induce in the young Wistar rat interruptions in the IEL which are morphologically very similar to those which form spontaneously." | 1.27 | [Formation of disruptions of the internal elastica lamina, spontaneous and BAPN induced, in arteries of stroke-prone spontaneously hypertensive rats]. ( Coutard, M; Osborne-Pellegrin, M, 1987) |
| "Among them, cerebral aneurysms were never found in rats without carotid ligation." | 1.26 | Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms. ( Handa, H; Hashimoto, N; Hazama, F; Nagata, I, 1980) |
| "These intracranial aneurysms have significant gross and microscopic similarities to human berry aneurysms." | 1.26 | Experimental intracranial aneurysms in rats. A gross and microscopic study. ( Popoff, N; Robertson, JT; Stadlan, EM; Suzuki, S; White, RP, 1980) |
| "Neurolathyrism in man may be caused by beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, a neurotoxin recently identified in Lathyrus sativus seeds." | 1.24 | Naturally occurring toxic factors in plants and animals used as food. ( Strong, FM, 1966) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (70.83) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Kondo, M | 1 |
| Izawa-Ishizawa, Y | 1 |
| Goda, M | 1 |
| Hosooka, M | 1 |
| Kagimoto, Y | 1 |
| Saito, N | 1 |
| Matsuoka, R | 1 |
| Zamami, Y | 1 |
| Chuma, M | 1 |
| Yagi, K | 1 |
| Takechi, K | 1 |
| Tsuneyama, K | 1 |
| Ishizawa, K | 1 |
| Kawai, T | 1 |
| Takayanagi, T | 1 |
| Forrester, SJ | 1 |
| Preston, KJ | 1 |
| Obama, T | 1 |
| Tsuji, T | 1 |
| Kobayashi, T | 1 |
| Boyer, MJ | 1 |
| Cooper, HA | 1 |
| Kwok, HF | 1 |
| Hashimoto, T | 2 |
| Scalia, R | 1 |
| Rizzo, V | 1 |
| Eguchi, S | 1 |
| Eberson, LS | 1 |
| Sanchez, PA | 1 |
| Majeed, BA | 1 |
| Tawinwung, S | 1 |
| Secomb, TW | 1 |
| Larson, DF | 1 |
| Kanematsu, Y | 1 |
| Kanematsu, M | 1 |
| Kurihara, C | 1 |
| Tsou, TL | 1 |
| Nuki, Y | 1 |
| Liang, EI | 1 |
| Makino, H | 1 |
| Hashimoto, N | 5 |
| Handa, H | 2 |
| Nagata, I | 3 |
| Hazama, F | 4 |
| Franklin, TJ | 1 |
| Morris, WP | 1 |
| Loveday, BE | 1 |
| Berry, CL | 1 |
| Greenwald, SE | 1 |
| Menahem, N | 1 |
| Hadna, H | 1 |
| Suzuki, S | 1 |
| Robertson, JT | 1 |
| White, RP | 1 |
| Stadlan, EM | 1 |
| Popoff, N | 1 |
| Coutard, M | 3 |
| Osborne-Pellegrin, M | 2 |
| Ooshima, A | 1 |
| Midorikawa, O | 1 |
| Sheridan, PJ | 1 |
| Kozar, LG | 1 |
| Benson, SC | 1 |
| Iwatsuki, K | 1 |
| Cardinale, GJ | 1 |
| Spector, S | 1 |
| Udenfriend, S | 1 |
| Ogawa, M | 1 |
| Ozaki, M | 1 |
| Isoyama, S | 1 |
| Ito, N | 1 |
| Satoh, K | 1 |
| Takishima, T | 1 |
| Nakashima, Y | 1 |
| Sueishi, K | 1 |
| Capdeville, M | 1 |
| Osborne-Pellegrin, MJ | 1 |
| Fischer, M | 1 |
| Wessler, D | 1 |
| Henrichs, KJ | 1 |
| Unger, T | 1 |
| Kim, C | 1 |
| Kikuchi, H | 1 |
| Kojima, M | 1 |
| Kang, Y | 1 |
| Wolinsky, H | 1 |
| Strong, FM | 1 |
1 review available for aminopropionitrile and Hypertension
| Article | Year |
|---|---|
Mesenchymal response of the blood vessel wall. A potential avenue for understanding and treating atherosclerosis.
Topics: Aminopropionitrile; Androgens; Animals; Arteriosclerosis; Blood Vessels; Cell Differentiation; Chole | 1973 |
23 other studies available for aminopropionitrile and Hypertension
| Article | Year |
|---|---|
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; At | 2020 |
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
Topics: ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdo | 2017 |
Effect of lysyl oxidase inhibition on angiotensin II-induced arterial hypertension, remodeling, and stiffness.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Male; Mice; Mice, | 2015 |
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, A | 2010 |
Saccular cerebral aneurysms in rats.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Humans; Hypertension; Intracranial Aneurysm; Rats; Th | 1983 |
Effects of inhibitors of collagen maturation on hypertension in rats.
Topics: Aminopropionitrile; Animals; Collagen; Desoxycorticosterone; Female; Hypertension; Hypertension, Ren | 1982 |
Effect of beta-aminopropionitrile on the static elastic properties and blood pressure of spontaneously hypertensive rats.
Topics: Aminopropionitrile; Animals; Aorta; Blood Pressure; Elasticity; Hypertension; Hypertension, Renal; M | 1981 |
[Experimental inducement of saccular cerebral aneuryms in rats (author's transl)].
Topics: Aminopropionitrile; Animals; Hypertension; Intracranial Aneurysm; Ligation; Rats | 1980 |
Experimentally induced cerebral aneurysms in rats: Part V. Relation of hemodynamics in the circle of Willis to formation of aneurysms.
Topics: Aminopropionitrile; Animals; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Circle of Wi | 1980 |
Experimental intracranial aneurysms in rats. A gross and microscopic study.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Cerebral Arteries; Desoxycorticosterone; Disease Mode | 1980 |
Genetic susceptibility to experimental cerebral aneurysm formation in the rat.
Topics: Aminopropionitrile; Animals; Carotid Artery, Common; Genetic Predisposition to Disease; Hypertension | 1997 |
Increased lysyl oxidase activity in blood vessels of hypertensive rats and effect of beta-aminopropionitrile on arteriosclerosis.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Arteries; Arteriosclerosis; Blood Pressure; | 1977 |
Increased lysyl oxidase activity in aortas of hypertensive rats and effect of beta-aminopropionitrile.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Aorta; Collagen; Desoxycorticosterone; Hype | 1979 |
Reduction of blood pressure and vascular collagen in hypertensive rats by beta-aminopropionitrile.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Animals; Aorta; Blood Pressure; Collagen; Desoxycort | 1977 |
[Experimental inducement of saccular cerebral aneurysms in rats (author's transl)].
Topics: Aminopropionitrile; Animals; Disease Models, Animal; Female; Hypertension; Intracranial Aneurysm; Li | 1979 |
Inhibitory effect of beta-aminopropionitrile on the development of hypertension in spontaneously hypertensive rats.
Topics: Aminopropionitrile; Animals; Body Weight; Collagen; Hypertension; Male; Norepinephrine; Rats; Time F | 1978 |
Collagen deposition and the reversal of coronary reserve in cardiac hypertrophy.
Topics: Aminopropionitrile; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Body Weight; Carbon Diox | 1992 |
Alteration of elastic architecture in the lathyritic rat aorta implies the pathogenesis of aortic dissecting aneurysm.
Topics: Aminopropionitrile; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Body Weight; | 1992 |
Spontaneous rupture of the internal elastic lamina in the rat: the manifestation of a genetically determined factor which may be linked to vascular fragility.
Topics: Aminopropionitrile; Aneurysm; Animals; Connective Tissue Diseases; Elastic Tissue; Elastin; Female; | 1989 |
[Formation of disruptions of the internal elastica lamina, spontaneous and BAPN induced, in arteries of stroke-prone spontaneously hypertensive rats].
Topics: Age Factors; Aminopropionitrile; Animals; Elastic Tissue; Endothelium, Vascular; Hypertension; Male; | 1987 |
Influence of beta-aminopropionitril on media hypertrophy and baroreceptor reflex in normotensive and hypertensive rats.
Topics: Aminopropionitrile; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Muscle, Sm | 1986 |
Experimental induction of cerebral aneurysms in monkeys.
Topics: Aminopropionitrile; Animals; Carotid Arteries; Cerebral Angiography; Disease Models, Animal; Female; | 1987 |
Naturally occurring toxic factors in plants and animals used as food.
Topics: Aminopropionitrile; Cyanides; Food Analysis; Glycosides; Goiter; Humans; Hypertension; Lathyrism; Me | 1966 |