bay-k-8644 has been researched along with Hypertension in 52 studies
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
---|---|---|
"The present study evaluates the response to the L-type voltage gated calcium channel agonist Bay K 8644 in two forms of experimental hypertension (mineralocorticoid- and hypertension induced by the nitric oxide synthase inhibitor N omega-nitro-L-arginine (N-Nitro arginine)) and under conditions of acute stretch." | 7.69 | Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension. ( Finta, KM; Lloyd, MC; Storm, DS; Watts, SW; Webb, RC, 1994) |
"Propofol acts as an L-type calcium channel (LTCC) antagonist to decrease peripheral resistance and initiate hypotension." | 5.38 | Role of L-type calcium channels in altered microvascular responses to propofol in hypertension. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2012) |
"To clarify whether the Ca2+ uptake function of the sarcoplasmic reticulum (SR) during arterial contraction is altered in hypertension, the effects of cyclopiazonic acid (CPA) and thapsigargin, which inhibit SR Ca2+-ATPase, on the contractile responses to Bay k 8644, an agonist of L-type Ca2+ channels, were compared in endothelium-denuded strips of carotid arteries from 13-week-old spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY)." | 3.71 | Ca2+ buffering function of the sarcoplasmic reticulum is increased in the carotid artery from spontaneously hypertensive rats. ( Asano, M; Nomura, Y, 2002) |
"The present study evaluates the response to the L-type voltage gated calcium channel agonist Bay K 8644 in two forms of experimental hypertension (mineralocorticoid- and hypertension induced by the nitric oxide synthase inhibitor N omega-nitro-L-arginine (N-Nitro arginine)) and under conditions of acute stretch." | 3.69 | Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension. ( Finta, KM; Lloyd, MC; Storm, DS; Watts, SW; Webb, RC, 1994) |
"Propofol acts as an L-type calcium channel (LTCC) antagonist to decrease peripheral resistance and initiate hypotension." | 1.38 | Role of L-type calcium channels in altered microvascular responses to propofol in hypertension. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2012) |
"Bezafibrate treatment lowered blood pressure, free fatty acids, and triglycerides in the fructose-fed group, suggesting that lipid abnormalities play a role in the elevation of blood pressure in the fructose-induced hypertensive rat." | 1.30 | Bezafibrate, an anti-hypertriglyceridemic drug, attenuates vascular hyperresponsiveness and elevated blood pressure in fructose-induced hypertensive rats. ( Richey, JM; Si, X; Webb, RC, 1999) |
"Treatment with ramipril reduced blood pressure and force development in response to Bay K8644 in adult SHRSP, although not to levels of WKY rats, whereas WKY rats were unaffected by treatment." | 1.29 | Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats. ( Traub, O; Webb, RC, 1993) |
"Hydralazine treatment and sodium deprivation did not significantly modify the pressure-independence of renin release by LH rat kidneys." | 1.29 | Pressure control of renal renin release in Lyon hypertensive rats. ( Bertolino, S; Medeiros, IA; Sassard, J; Zhang, BL, 1994) |
"Nifedipine was less efficacious in relaxing the contractile response to Bay k 8644 compared to the contractile response to K+ in SHRs femoral arteries." | 1.27 | Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats. ( Aoki, K; Asano, M; Matsuda, T, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (17.31) | 18.7374 |
1990's | 34 (65.38) | 18.2507 |
2000's | 5 (9.62) | 29.6817 |
2010's | 3 (5.77) | 24.3611 |
2020's | 1 (1.92) | 2.80 |
Authors | Studies |
---|---|
Vo, D | 1 |
Matowe, WC | 1 |
Ramesh, M | 1 |
Iqbal, N | 1 |
Wolowyk, MW | 1 |
Howlett, SE | 1 |
Knaus, EE | 1 |
Lin, YK | 1 |
Chen, YJ | 1 |
Li, JY | 1 |
Chen, YL | 1 |
He, D | 1 |
Zuo, R | 1 |
Xiao, MJ | 1 |
Xu, DP | 1 |
Zheng, CY | 1 |
Wang, W | 1 |
He, RR | 1 |
Chen, Y | 1 |
Lloyd, EE | 1 |
Crossland, RF | 1 |
Phillips, SC | 1 |
Marrelli, SP | 1 |
Reddy, AK | 1 |
Taffet, GE | 1 |
Hartley, CJ | 1 |
Bryan, RM | 1 |
Grześk, G | 1 |
Wiciński, M | 1 |
Malinowski, B | 1 |
Grześk, E | 1 |
Manysiak, S | 1 |
Odrowąż-Sypniewska, G | 1 |
Darvish, N | 1 |
Bierwagen, M | 1 |
Lawton, BK | 1 |
Brown, NJ | 1 |
Reilly, CS | 1 |
Brookes, ZL | 1 |
David, FL | 1 |
Montezano, AC | 1 |
Rebouças, NA | 1 |
Nigro, D | 1 |
Fortes, ZB | 1 |
Carvalho, MH | 1 |
Tostes, RC | 3 |
Garthoff, B | 1 |
Kazda, S | 1 |
Luckhaus, G | 1 |
Asano, M | 6 |
Nomura, Y | 4 |
Ito, K | 1 |
Uyama, Y | 1 |
Imaizumi, Y | 1 |
Watanabe, M | 1 |
Traub, O | 2 |
Webb, RC | 8 |
Lal, KJ | 1 |
Dakshinamurti, K | 1 |
Wilde, DW | 2 |
Furspan, PB | 1 |
Szocik, JF | 1 |
Medeiros, IA | 1 |
Zhang, BL | 1 |
Bertolino, S | 1 |
Sassard, J | 1 |
Watts, SW | 2 |
Finta, KM | 1 |
Lloyd, MC | 1 |
Storm, DS | 3 |
Hérembert, T | 1 |
Zhu, DL | 1 |
Marche, P | 1 |
Ribeiro, MO | 1 |
Antunes, E | 1 |
Muscará, MN | 1 |
De Nucci, G | 1 |
Zatz, R | 1 |
Mertens, MJ | 1 |
Pfaffendorf, M | 2 |
Van Zwieten, PA | 2 |
Huguet, F | 1 |
Brisac, AM | 2 |
Dubar, M | 1 |
Ingrand, P | 1 |
Piriou, A | 1 |
Hui, C | 2 |
Goto, A | 2 |
Yamada, K | 2 |
Yagi, N | 2 |
Nagoshi, H | 2 |
Sasabe, M | 2 |
Omata, M | 2 |
Hernández, MC | 1 |
Salaices, M | 2 |
Ponte, A | 1 |
Alonso, MJ | 1 |
Sánchez-Ferrer, CF | 1 |
Marín, J | 2 |
Beenen, OH | 1 |
Tsuda, K | 2 |
Tsuda, S | 2 |
Nishio, I | 1 |
Masuyama, Y | 2 |
Goldstein, M | 2 |
Bendhack, LM | 1 |
McConnell, BK | 1 |
Moravec, CS | 1 |
Morano, I | 1 |
Bond, M | 1 |
Le Roy, AL | 1 |
Messer-Létienne, I | 1 |
Bernard, N | 1 |
Benzoni, D | 1 |
Ren, J | 3 |
Brown, RA | 3 |
Sugimoto, T | 1 |
Jefferson, L | 2 |
Sudan, N | 1 |
Lloyd, TC | 1 |
Manso, AM | 1 |
Encabo, A | 1 |
Ferrer, M | 1 |
Balfagón, G | 1 |
Si, X | 1 |
Richey, JM | 1 |
Sowers, JR | 1 |
Chi, DH | 1 |
Mukundan, H | 1 |
Kanagy, NL | 1 |
Kamata, K | 1 |
Miyata, N | 1 |
Kasuya, Y | 1 |
Boonen, HC | 1 |
De Mey, JG | 1 |
Jubelin, BC | 1 |
Kannan, MS | 1 |
Turla, MB | 1 |
Todd, KM | 1 |
Bruner, CA | 1 |
Yu, Z | 1 |
McNeill, JH | 1 |
Takeshita, H | 1 |
Nishikibe, M | 1 |
Yano, M | 1 |
Ikemoto, F | 1 |
Docherty, JR | 2 |
Warnock, P | 2 |
Aoki, K | 2 |
Matsuda, T | 1 |
Steele, TH | 2 |
Challoner-Hue, L | 1 |
Lacolley, P | 1 |
Laurent, S | 1 |
Tsoucaris-Kupfer, D | 1 |
Legrand, M | 1 |
Schmitt, H | 1 |
Bolzon, BJ | 1 |
Cheung, DW | 1 |
2 reviews available for bay-k-8644 and Hypertension
Article | Year |
---|---|
Calcium handling by vascular myocytes in hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Calcium entry modulation and renal hemodynamics in the hypertensive kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
50 other studies available for bay-k-8644 and Hypertension
Article | Year |
---|---|
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Salvianolic acid A from Danhong Injection induces vasorelaxation by Regulating L-type calcium channel in isolated mouse arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2022 |
Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 2011 |
Calcium blockers inhibit cyclosporine A-induced hyperreactivity of vascular smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2012 |
Role of L-type calcium channels in altered microvascular responses to propofol in hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2012 |
Gender differences in vascular expression of endothelin and ET(A)/ET(B) receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
'Calcium agonist' in salt-dependent hypertension: hints at calcium-mediated blood pressure increase.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Increased function of voltage-dependent Ca++ channels and Ca(++)-activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Calcium channels in vitamin B6 deficiency-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Calcium current in smooth muscle cells from normotensive and genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Pressure control of renal renin release in Lyon hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Mechanism of action of the inhibitory effect of nifedipine on the growth of cultured aortic cells from spontaneously hypertensive and normotensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Nifedipine prevents renal injury in rats with chronic nitric oxide inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 1995 |
Sensitivity of cardiac tissues with moderate and advanced hypertrophy to calcium ions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Endothelin modulates dihydropyridine receptor decreased binding in hippocampal slices from normotensive and spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Modulation of vascular calcium channel activity in response to acute volume expansion in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
Effects of Bay K 8644 in aorta from spontaneously hypertensive and Wistar Kyoto rats of different ages.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Contractile responses to various inotropic agents in isolated hearts obtained from hypertensive diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Synergistic effects of Bay K 8644 and bradykinin on norepinephrine release in the hypothalamus of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1997 |
Effects of L-type calcium channel activation on renal vascular resistances in the Lyon hypertensive rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Hypertension augments ethanol-induced depression of cell shortening and intracellular Ca(2+) transients in adult rat ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Relations of vascular calcium channels with blood pressure and endothelium in hypertension and with aging.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Acetaldehyde depresses myocardial contraction and cardiac myocyte shortening in spontaneously hypertensive rats: role of intracellular Ca2+.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Changes of cardiac calcium homeostasis in spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Bezafibrate, an anti-hypertriglyceridemic drug, attenuates vascular hyperresponsiveness and elevated blood pressure in fructose-induced hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Intracellular calcium stores and oscillatory contractions in arteries from genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
Calcium buffering of resting, voltage-dependent Ca2+ influx by sarcoplasmic reticulum in femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
Ca2+ influx mediates enhanced alpha2-adrenergic contraction in aortas from rats treated with NOS inhibitor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
Ca2+ buffering function of the sarcoplasmic reticulum is increased in the carotid artery from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Increased Ca2+ buffering function of sarcoplasmic reticulum in small mesenteric arteries from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Effects of endothelin on the portal vein from spontaneously hypertensive and Wistar Kyoto rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Neurons from neonatal hypertensive rats exhibit abnormal membrane properties in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Calcium and contractile responses to phorbol esters and the calcium channel agonist, Bay K 8644, in arteries from hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Increased vascular reactivity to Bay K 8644 in genetic hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Altered inotropic responses in diabetic cardiomyopathy and hypertensive-diabetic cardiomyopathy.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Effects of Bay K 8644, a Ca2+ channel agonist, on [3H]norepinephrine release in hypothalamus of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Coronary vascular response to endothelin in isolated perfused hearts of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
An investigation of alpha-adrenoceptor responsiveness in the vas deferens of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1985 |
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Reduced alpha 1-adrenoreceptor mediated responsiveness in vas deferens from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Exaggerated Dahl salt-sensitive kidney response to calcium channel agonist isomer of Bay k 8644, but not to calcium channel antagonist isomer of Bay k 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
[Central control of the baroreflex response to phenylephrine by dihydropyridines in the anesthetized rat].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Isolation and characterization of single vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |