1,3-dicyclohexylurea has been researched along with Hypertension in 3 studies
1,3-dicyclohexylurea: degradation product of 1-(2-chloroethyl)-3- cyclohexyl-1-nitrosourea; structure
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 1,3-dicyclohexylurea (DCU), a potent sEH inhibitor, lowers systemic blood pressure in spontaneously hypertensive rats when dosed intraperitoneally." | 1.35 | Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. ( Chiang, PC; Fujiwara, H; Ghosh, S; Roberds, SL; Selbo, JG; Wahlstrom, JL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pecic, S | 1 |
| Deng, SX | 1 |
| Morisseau, C | 2 |
| Hammock, BD | 2 |
| Landry, DW | 1 |
| Ghosh, S | 1 |
| Chiang, PC | 1 |
| Wahlstrom, JL | 1 |
| Fujiwara, H | 1 |
| Selbo, JG | 1 |
| Roberds, SL | 1 |
| Yu, Z | 1 |
| Xu, F | 1 |
| Huse, LM | 1 |
| Draper, AJ | 1 |
| Newman, JW | 1 |
| Parker, C | 1 |
| Graham, L | 1 |
| Engler, MM | 1 |
| Zeldin, DC | 1 |
| Kroetz, DL | 1 |
3 other studies available for 1,3-dicyclohexylurea and Hypertension
| Article | Year |
|---|---|
Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase.
Topics: Amides; Chemistry, Pharmaceutical; Drug Design; Enzyme Inhibitors; Epoxide Hydrolases; Fluorescent D | 2012 |
Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.
Topics: 8,11,14-Eicosatrienoic Acid; Administration, Oral; Animals; Blood Pressure; Chromatography, Liquid; | 2008 |
Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Blood Pressure; Cytosol; Eicosanoids; Enzym | 2000 |