Page last updated: 2024-09-03

candoxatrilat and Hypertension

candoxatrilat has been researched along with Hypertension in 5 studies

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ballard, SA; Bennett, T; Gardiner, SM; Kemp, PA; March, JE	1
Wilkins, MR	1
Aoyama, T; Iimura, O; Iwata, M; Nomura, N; Shimamoto, K; Takagawa, Y; Ura, N	1
Ferro, CJ; Haynes, WG; Spratt, JC; Webb, DJ	1
Barclay, PL; Bennett, JA; Samuels, GM; Shepperson, NB	1

Reviews

1 review(s) available for candoxatrilat and Hypertension

Article	Year
Clinical potential of endopeptidase-24.11 inhibitors in cardiovascular disease. Biochemical Society transactions, 1993, Volume: 21 ( Pt 3), Issue:3 Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diuretics; Drug Design; Heart Failure; Humans; Hypertension; Indans; Neprilysin; Propionates; Protease Inhibitors; Thiorphan	1993

Trials

1 trial(s) available for candoxatrilat and Hypertension

Article	Year
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo. Circulation, 1998, Jun-16, Volume: 97, Issue:23 Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Coronary Vessels; Cross-Over Studies; Cyclohexanecarboxylic Acids; Enalapril; Endothelin-1; Humans; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Myocardium; Neprilysin; Peptides, Cyclic; Protease Inhibitors; Renin; Single-Blind Method; Thiorphan; Vasoconstriction	1998

Article

Year

Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.

Circulation, 1998, Jun-16, Volume: 97, Issue:23

Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Coronary Vessels; Cross-Over Studies; Cyclohexanecarboxylic Acids; Enalapril; Endothelin-1; Humans; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Myocardium; Neprilysin; Peptides, Cyclic; Protease Inhibitors; Renin; Single-Blind Method; Thiorphan; Vasoconstriction

1998

Other Studies

3 other study(ies) available for candoxatrilat and Hypertension

Article	Year
Regional hemodynamic effects of neutral endopeptidase inhibition and angiotensin (AT(1)) receptor antagonism alone or in combination in conscious spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cyclohexanecarboxylic Acids; Heart Rate; Hypertension; Losartan; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Inbred SHR; Renal Circulation	2006
The role of kinins and atrial natriuretic peptide on the renal effects of neutral endopeptidase inhibitor in normotensive and hypertensive rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:8 Topics: Adrenergic beta-Antagonists; Animals; Atrial Natriuretic Factor; Bradykinin; Cyclohexanecarboxylic Acids; Desoxycorticosterone; Hypertension; Kidney; Kinins; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Sprague-Dawley	1995
Inhibition of neutral endopeptidase (EC 3.4.24.11) leads to an atrial natriuretic factor-mediated natriuretic, diuretic and antihypertensive response in rodents. Clinical science (London, England : 1979), 1991, Volume: 80, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclohexanecarboxylic Acids; Desoxycorticosterone; Diuresis; Hypertension; Immune Sera; Natriuresis; Neprilysin; Rats; Rats, Inbred Strains	1991