| Assay ID | Title | Year | Journal | Article |
|---|
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347411 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7
| High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1891960 | Inhibition of recombinant MAGL (unknown origin) expressed in COS7 cells assessed as blockade of substrate hydrolysis using AEA as substrate preincubated with compound for 30 mins followed by susbstrate addition | 2022 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 68 | Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. |
| AID703152 | Inhibition of bacterial lipoprotein lipase at 10 uM by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID703155 | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10000 nM by scintillation counting based radio-TLC assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID1890732 | Inhibition of human recombinant MAGL incubated for 5 mins followed by substrate addition by cayman fluorescence based multimode microplate reader assay | 2022 | Bioorganic & medicinal chemistry, 04-15, Volume: 60 | Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. |
| AID703150 | Inhibition of porcine pancreatic lipase type 2 at 10 uM by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID703158 | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 nM by scintillation counting based radio-TLC assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID703171 | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM using JZL184 pretreated protein in detergent free solution by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID1867628 | Inhibition of human recombinant FAAH using AMC-AA as substrate preincubated with enzyme for 10 mins followed by substrate addition for 2 hrs by fluorometric analysis | 2022 | European journal of medicinal chemistry, Jul-05, Volume: 237 | Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. |
| AID458310 | Toxicity in mouse assessed as death at 20 mg/kg, ip for 6 days | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID703157 | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 100 nM by scintillation counting based radio-TLC assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID458301 | Inhibition of MAGL in mouse brain membrane | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID458309 | In vivo inhibition of MAGL in mouse at 100 mg/kg, po | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID1655068 | Inhibition of human recombinant MAGL pre-incubated for 5 mins before MAGL substrate addition and further incubated for 10 mins | 2020 | Journal of medicinal chemistry, 06-11, Volume: 63, Issue:11
| Discovery of Aryl Formyl Piperidine Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase Inhibitors. |
| AID458304 | Inhibition of NTE in mouse brain membrane | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID1867627 | Inhibition of human BuChE by Ellman's spectrophotometric method | 2022 | European journal of medicinal chemistry, Jul-05, Volume: 237 | Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. |
| AID1890731 | Inhibition of recombinant human FAAH incubated for 5 mins followed by substrate addition by cayman fluorescence based multimode microplate reader assay | 2022 | Bioorganic & medicinal chemistry, 04-15, Volume: 60 | Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. |
| AID458302 | Inhibition of ABHD6 in mouse brain membrane | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID458306 | In vivo inhibition of FAAH in mouse at 20 mg/kg, ip | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID458300 | Inhibition of FAAH in mouse brain membrane | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID703154 | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in detergent free solution by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID458307 | In vivo inhibition of FAAH in mouse at 100 mg/kg, po | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID703156 | Inhibition of mouse DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 1000 nM by scintillation counting based radio-TLC assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID1053375 | Inhibition of TAMRA-FP-labeled FAAH in mouse brain membrane at 10 uM after 1 hr by fluorescent gel scanning assay | 2013 | Journal of medicinal chemistry, Nov-14, Volume: 56, Issue:21
| Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors. |
| AID1891959 | Inhibition of recombinant FAAH (unknown origin) expressed in COS7 cells assessed as blockade of substrate hydrolysis using 2-AG as substrate preincubated with compound for 30 mins followed by substrate addition | 2022 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 68 | Design and synthesis of endocannabinoid enzyme inhibitors for ocular indications. |
| AID1867626 | Inhibition of human AChE by Ellman's spectrophotometric method | 2022 | European journal of medicinal chemistry, Jul-05, Volume: 237 | Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease. |
| AID703169 | Inhibition of human DAGLalpha expressed in HEK293T cell membrane using [14C]SAG substrate at 10 uM in detergent free solution by scintillation counting based radio-TLC assay | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
| Assay and inhibition of diacylglycerol lipase activity. |
| AID458308 | In vivo inhibition of MAGL in mouse at 20 mg/kg, ip | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID458305 | Inhibition of NTE in mouse brain membrane at 100 uM | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4
| Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1346214 | Human acyloxyacyl hydrolase (3.1.1.- Carboxylic Ester Hydrolases) | 2014 | Nature chemical biology, Aug, Volume: 10, Issue:8
| A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. |
| AID1345299 | Human Fatty acid amide hydrolase (Hydrolases) | 2009 | Proceedings of the National Academy of Sciences of the United States of America, Dec-01, Volume: 106, Issue:48
| Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. |
| AID1345301 | Human Monoacylglycerol lipase (2-Acylglycerol ester turnover) | 2009 | Proceedings of the National Academy of Sciences of the United States of America, Dec-01, Volume: 106, Issue:48
| Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |