Page last updated: 2024-09-03

n(6)-carboxymethyllysine and Hypertension

n(6)-carboxymethyllysine has been researched along with Hypertension in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (66.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Böhm, M; Ewen, S; Hohl, M; Kazakov, A; Kindermann, I; Laufs, U; Linz, D; Mahfoud, F; Selejan, SR; Speer, T; Tatu, AM; Zamyatkin, O1
Agostoni, P; Aldini, G; Banfi, C; Brioschi, M; Gianazza, E; Martinez Fernandez, A; Regazzoni, L1
Ferrucci, L; Garcia, M; Harris, TB; Newman, AB; Satterfield, S; Schwartz, AV; Semba, RD; Sun, K; Varadhan, R1
Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP1
Hartog, JW; Voors, AA; Willemsen, S1
Hartog, JW; Jaarsma, W; Miyata, T; Plokker, HW; Schalkwijk, CG; Smit, AJ; van de Wal, RM; van Veldhuisen, DJ; van Wijk, LM; Voors, AA1
Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T1
Baliga, S; Cai, W; Goldberg, T; Lu, M; Peppa, M; Uribarri, J; Vassalotti, JA; Vlassara, H1
Abe, M; Hisano, S; Horiuchi, S; Iwasaki, H; Nangaku, M; Sakata, N; Uesugi, N1
de Champlain, J; Desai, K; Juurlink, BH; Wang, X; Wu, L1
Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G1
Durante, A; Monacelli, F; Odetti, P; Poggi, A; Storace, D; Traverso, N; Viviani, GL1
Baumann, M; Heemann, U; Schalkwijk, C; Scheijen, J; Stehouwer, C; Struijker Boudier, H1
Chang, T; Desai, K; Jia, X; Wang, X; Wu, L1
Busch, M; Franke, S; Rohde, RD; Stein, G; Wolf, G1

Trials

3 trial(s) available for n(6)-carboxymethyllysine and Hypertension

ArticleYear
Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
    European journal of heart failure, 2010, Volume: 12, Issue:4

    Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Female; Glycation End Products, Advanced; Humans; Hypertension; Imidazoles; Linear Models; Lysine; Male; Middle Aged; Multivariate Analysis; Netherlands; Skin; Statistics as Topic; Statistics, Nonparametric; Stroke Volume; Thiophenes; Ventricular Function, Left

2010
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Lysine; Male; Middle Aged; Prognosis; Tetrazoles

2011
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
    Nephron. Clinical practice, 2008, Volume: 108, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles

2008

Other Studies

12 other study(ies) available for n(6)-carboxymethyllysine and Hypertension

ArticleYear
Sympathoadrenergic suppression improves heart function by upregulating the ratio of sRAGE/RAGE in hypertension with metabolic syndrome.
    Journal of molecular and cellular cardiology, 2018, Volume: 122

    Topics: ADAM10 Protein; Analysis of Variance; Animals; Denervation; Disease Models, Animal; Fibroblasts; HMGB1 Protein; Hypertension; Kidney; Leukocytes, Mononuclear; Ligands; Lysine; Male; Metabolic Syndrome; Myocardium; Obesity; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Adrenergic, beta; Statistics, Nonparametric; Sympathetic Nervous System; Up-Regulation

2018
Pro-oxidant and pro-inflammatory effects of glycated albumin on cardiomyocytes.
    Free radical biology & medicine, 2019, 11-20, Volume: 144

    Topics: Aged; Case-Control Studies; Cell Death; Cell Line; Dyslipidemias; Female; Gene Expression Profiling; Gene Ontology; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Heart Failure; HSP90 Heat-Shock Proteins; Humans; Hypertension; Interleukin-6; Lysine; Male; Middle Aged; Molecular Sequence Annotation; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Protein Carbonylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Serum Albumin; Serum Albumin, Human; Tumor Necrosis Factor-alpha

2019
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults.
    Journal of hypertension, 2015, Volume: 33, Issue:4

    Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness

2015
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
    Circulation, 2008, Sep-02, Volume: 118, Issue:10

    Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left

2008
Letter by Hartog et al. regarding article, "Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines".
    Circulation, 2009, Mar-17, Volume: 119, Issue:10

    Topics: Animals; Arginine; Collagen; Cross-Linking Reagents; Dogs; Glycation End Products, Advanced; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles

2009
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3

    Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia

2003
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: glycoxidation-mediated local complement activation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2004, Volume: 44, Issue:2

    Topics: Acrolein; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Complement Activation; Complement Membrane Attack Complex; Diabetic Nephropathies; Female; Glomerulosclerosis, Focal Segmental; Glycation End Products, Advanced; Humans; Hypertension; Kidney; Kidney Glomerulus; Lysine; Male; Middle Aged; Models, Biological; Nephrosclerosis; Oxidation-Reduction; Tunica Media

2004
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats.
    Kidney international, 2006, Volume: 69, Issue:2

    Topics: Animals; Female; Glycation End Products, Advanced; Hypertension; Immunohistochemistry; Kidney; Lysine; Male; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sex Characteristics; Transcription Factor RelA

2006
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:4

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors

2006
Effects of valsartan therapy on protein glycoxidation.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:12

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Dinoprost; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Lysine; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Proteins; Tetrazoles; Valine; Valsartan

2006
N epsilon-(carboxymethyl)lysine during the early development of hypertension.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Albuminuria; Animals; Blood Pressure; Creatinine; Glycation End Products, Advanced; Heart Rate; Humans; Hypertension; Lysine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2008
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats.
    Journal of hypertension, 2008, Volume: 26, Issue:4

    Topics: Animals; Aorta; Dietary Carbohydrates; Fructose; Glutathione; Glycation End Products, Advanced; Hydrogen Peroxide; Hypertension; Hypoglycemic Agents; Lysine; Male; Mesenteric Arteries; Metformin; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2008