Compounds > germitrine
Page last updated: 2024-11-13

germitrine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Cross-References

ID SourceID
PubMed CID90479349
MeSH IDM0061360

Synonyms (13)

Synonym
unii-u1g91m951m
u1g91m951m ,
4-21-00-06809 (beilstein handbook reference)
560-48-5
germine 3-(1)-2-methylbutyrate 7-acetate 15(d)-2-hydroxyl-2-methylbutyrate
germitrine
germitrin
brn 0076383
cevane-3-beta,4-beta,7-alpha,14,15-alpha,16-beta,20-heptol, 4,9-epoxy-, 7-acetate, 15-((+)-2-hydroxy-2-methylbutyrate) 3-((-)-2-methylbutyrate)
cevane-3.beta.,4.beta.,7.alpha.,14,15.alpha.,16.beta.,20-heptol, 4,9-epoxy-, 7-acetate 15-((+)-2-hydroxy-2-methylbutyrate) 3-((-)-2-methylbutyrate)
cevane-3,4,7,14,15,16,20-heptol, 4,9-epoxy-, 7-acetate 3-(2-hydroxy-2-methylbutanoate) 15-(2-methylbutanoate), (3.beta.(s),4.alpha.,7.alpha.,15.alpha.(r),16.beta.)-
cevane-3,4,7,14,15,16,20-heptol, 4,9-epoxy-, 7-acetate 3-((2s)-2-hydroxy-2-methylbutanoate) 15-((2r)-2-methylbutanoate), (3.beta.,4.alpha.,7.alpha.,15.alpha.,16.beta.)-
Q27290558
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
veratramine
veratramine: structure. veratramine : A piperidine alkaloid comprising the 14,15,16,17-tetradehydro derivative of veratraman having two hydroxy groups at the 3- and 23-positions.		7.3420piperidine alkaloid
protoverin
Protoveratrines: Mixtures of closely related hypotensive alkaloids from Veratrum album (Liliaceae). They have been used in the treatment of hypertension but have largely been replaced by drugs with fewer adverse effects.		2.3420
germine
germine: alkamine; present in many polyester alkaloids which occur in Veratrum & Zydadenus species; may be used medically as an antihypertensive agent; minor descriptor (75-83); on-line & Index Medicus search CEVANES (75-83); RN given refers to parent cpd; structure		1.9510
protoverine
protoverine: RN given refers to (3beta,4alpha,6alpha,7alpha,15alpha,16beta)-isomer		1.9510alkaloid
veratrine
Veratrine: A voltage-gated sodium channel activator.		1.9510alkaloid
tetrodotoxin
Tetrodotoxin: An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.. tetrodotoxin : A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.		7.3620azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
veratridine
Veratridine: A benzoate-cevane found in VERATRUM and Schoenocaulon. It activates SODIUM CHANNELS to stay open longer than normal.		7.3420
ConditionIndicatedRelationship StrengthStudiesTrials
Blood Pressure, High
[description not available]		01.9210
Blood Pressure, Low
[description not available]		01.9210
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.		01.9210
Hypotension
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.		01.9210