Compounds > 1-2-3-4-tetrahydropyrimidine-2-thione

1-2-3-4-tetrahydropyrimidine-2-thione and Hypertension

1-2-3-4-tetrahydropyrimidine-2-thione has been researched along with Hypertension* in 1 studies

Other Studies

1 other study(ies) available for 1-2-3-4-tetrahydropyrimidine-2-thione and Hypertension

Article	Year
Synthesis and evaluation of some 1,2,3,4-tetrahydropyrimidine-2-thione and condensed pyrimidine derivatives as potential antihypertensive agents. Arzneimittel-Forschung, 2006, Volume: 56, Issue:5 Some new tetrahydropyrimidine-2-thione, octahydroquinazoline-2-thione and thiazolo[3,2-a]pyrimidine derivatives have been synthesized and tested for their antihypertensive activity. Among them, compounds 1 and 2b can be considered more potent than the reference, nifedipine (CAS 21829-25-4), while compounds 3b and 10a are equipotent to it. In addition, compound 6 showed significant antihypertensive activity. Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Hypertension; Indicators and Reagents; Male; Pyrimidines; Rats; Rats, Sprague-Dawley	2006

Article

Year

Synthesis and evaluation of some 1,2,3,4-tetrahydropyrimidine-2-thione and condensed pyrimidine derivatives as potential antihypertensive agents.

Arzneimittel-Forschung, 2006, Volume: 56, Issue:5

Some new tetrahydropyrimidine-2-thione, octahydroquinazoline-2-thione and thiazolo[3,2-a]pyrimidine derivatives have been synthesized and tested for their antihypertensive activity. Among them, compounds 1 and 2b can be considered more potent than the reference, nifedipine (CAS 21829-25-4), while compounds 3b and 10a are equipotent to it. In addition, compound 6 showed significant antihypertensive activity.

Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Hypertension; Indicators and Reagents; Male; Pyrimidines; Rats; Rats, Sprague-Dawley

2006