| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Hepatic Veno Occlusive Disease
[description not available] | 0 | 20.08 | 188 | 50 |
Hepatic Veno-Occlusive Disease
Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by THROMBOSIS. Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion and sinusoidal obstruction. | 0 | 20.08 | 188 | 50 |
Colorectal Cancer
[description not available] | 0 | 2.41 | 1 | 0 |
Hyperplasia
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. | 0 | 7.41 | 1 | 0 |
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 2.41 | 1 | 0 |
Blood Clot
[description not available] | 0 | 9.27 | 20 | 3 |
Thrombosis
Formation and development of a thrombus or blood clot in the blood vessel. | 0 | 9.27 | 20 | 3 |
Vascular Diseases
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body. | 0 | 7.13 | 14 | 1 |
Hematologic Malignancies
[description not available] | 0 | 5.33 | 4 | 1 |
Graft-Versus-Host Disease
[description not available] | 0 | 15.65 | 47 | 32 |
Graft vs Host Disease
The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. | 0 | 15.65 | 47 | 32 |
Hematologic Neoplasms
Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 5.33 | 4 | 1 |
Thrombotic Microangiopathies
Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation. | 0 | 8.31 | 7 | 2 |
2019 Novel Coronavirus Disease
[description not available] | 0 | 7.32 | 11 | 1 |
Acute Respiratory Distress Syndrome
[description not available] | 0 | 5.2 | 2 | 1 |
Respiratory Distress Syndrome
A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. | 0 | 5.2 | 2 | 1 |
Benign Neoplasms, Brain
[description not available] | 0 | 2.41 | 1 | 0 |
Metastase
[description not available] | 0 | 2.41 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.41 | 1 | 0 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.41 | 1 | 0 |
Lung Injury, Acute
[description not available] | 0 | 2.6 | 1 | 0 |
Experimental Lung Inflammation
Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 2.6 | 1 | 0 |
Pneumonia
Infection of the lung often accompanied by inflammation. | 0 | 7.6 | 1 | 0 |
Acute Lung Injury
A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). | 0 | 2.6 | 1 | 0 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 7.17 | 7 | 2 |
Chronic Kidney Diseases
[description not available] | 0 | 2.25 | 1 | 0 |
Uremia
A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms. | 0 | 4.86 | 4 | 2 |
Renal Insufficiency, Chronic
Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) | 0 | 2.25 | 1 | 0 |
Respiration Disorders
Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available. | 0 | 3.17 | 1 | 0 |
Acute Kidney Failure
[description not available] | 0 | 4.15 | 6 | 0 |
Bleeding
[description not available] | 0 | 6.6 | 6 | 2 |
MODS
[description not available] | 0 | 16.45 | 53 | 38 |
Hemorrhage
Bleeding or escape of blood from a vessel. | 0 | 6.6 | 6 | 2 |
Multiple Organ Failure
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. | 0 | 16.45 | 53 | 38 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 4.15 | 6 | 0 |
Bilirubinemia
[description not available] | 0 | 2.47 | 2 | 0 |
Acute Myelogenous Leukemia
[description not available] | 0 | 2.48 | 2 | 0 |
Pulmonary Veno Occlusive Disease
[description not available] | 0 | 4.58 | 5 | 0 |
Pulmonary Arterial Hypertension
A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY. | 0 | 2.25 | 1 | 0 |
Ascites
Accumulation or retention of free fluid within the peritoneal cavity. | 0 | 9.73 | 10 | 9 |
Pulmonary Veno-Occlusive Disease
Pathological process resulting in the fibrous obstruction of the small- and medium-sized PULMONARY VEINS and PULMONARY HYPERTENSION. Veno-occlusion can arise from fibrous proliferation of the VASCULAR INTIMA and VASCULAR MEDIA; THROMBOSIS; or a combination of both. | 0 | 4.58 | 5 | 0 |
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 2.48 | 2 | 0 |
Complication, Postoperative
[description not available] | 0 | 9.22 | 22 | 16 |
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 9.22 | 22 | 16 |
Hypercoagulability
[description not available] | 0 | 3.6 | 2 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 4.89 | 5 | 0 |
Idiopathic Interstitial Pneumonia
[description not available] | 0 | 3.6 | 2 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 4.89 | 5 | 0 |
Thrombophilia
A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS. | 0 | 3.6 | 2 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 3.79 | 11 | 0 |
Coagulation Disorders, Blood
[description not available] | 0 | 4.25 | 5 | 0 |
Blood Coagulation Disorders
Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions. | 0 | 4.25 | 5 | 0 |
Benign Neoplasms
[description not available] | 0 | 11.4 | 15 | 12 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 11.4 | 15 | 12 |
Infections, Coronavirus
[description not available] | 0 | 2.25 | 1 | 0 |
Inflammatory Response Syndrome, Systemic
[description not available] | 0 | 2.25 | 1 | 0 |
Pyrexia
[description not available] | 0 | 3.48 | 2 | 0 |
Colicky Pain
[description not available] | 0 | 2.25 | 1 | 0 |
Fever
An abnormal elevation of body temperature, usually as a result of a pathologic process. | 0 | 3.48 | 2 | 0 |
Pneumonia, Viral
Inflammation of the lung parenchyma that is caused by a viral infection. | 0 | 2.25 | 1 | 0 |
Abdominal Pain
Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 2.25 | 1 | 0 |
Coronavirus Infections
Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE). | 0 | 2.25 | 1 | 0 |
Systemic Inflammatory Response Syndrome
A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever | 0 | 2.25 | 1 | 0 |
HbS Disease
[description not available] | 0 | 2.31 | 1 | 0 |
Angiitis
[description not available] | 0 | 2.31 | 1 | 0 |
Anemia, Sickle Cell
A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. | 0 | 2.31 | 1 | 0 |
Vasculitis
Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body. | 0 | 2.31 | 1 | 0 |
Critical Illness
A disease or state in which death is possible or imminent. | 0 | 2.31 | 1 | 0 |
Blood Poisoning
[description not available] | 0 | 2.59 | 2 | 0 |
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 7.59 | 2 | 0 |
Cancer of Kidney
[description not available] | 0 | 5.1 | 3 | 1 |
Local Neoplasm Recurrence
[description not available] | 0 | 3.33 | 1 | 0 |
Kidney Neoplasms
Tumors or cancers of the KIDNEY. | 0 | 5.1 | 3 | 1 |
Biliary Cirrhosis
[description not available] | 0 | 2.31 | 1 | 0 |
Liver Cirrhosis, Biliary
FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes. | 0 | 2.31 | 1 | 0 |
chronic COVID syndrome
[description not available] | 0 | 3.23 | 1 | 0 |
Becker Muscular Dystrophy
[description not available] | 0 | 3.06 | 1 | 0 |
Elevated Cholesterol
[description not available] | 0 | 3.62 | 3 | 0 |
Age-Related Macular Degeneration
[description not available] | 0 | 3.06 | 1 | 0 |
Adult Spinal Muscular Atrophy
[description not available] | 0 | 3.06 | 1 | 0 |
Cytomegaloviral Retinitis
[description not available] | 0 | 3.06 | 1 | 0 |
Hypercholesterolemia
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 8.62 | 3 | 0 |
Macular Degeneration
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. | 0 | 3.06 | 1 | 0 |
Muscular Atrophy, Spinal
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089) | 0 | 3.06 | 1 | 0 |
Cytomegalovirus Retinitis
Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in AIDS patients and can cause blindness. | 0 | 3.06 | 1 | 0 |
Muscular Dystrophy, Duchenne
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415) | 0 | 3.06 | 1 | 0 |
Kahler Disease
[description not available] | 0 | 6.65 | 7 | 1 |
Multiple Myeloma
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 6.65 | 7 | 1 |
Diffuse Large B-Cell Lymphoma
[description not available] | 0 | 2.15 | 1 | 0 |
Lymphoma, Large B-Cell, Diffuse
Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. | 0 | 2.15 | 1 | 0 |
Acute Lymphoid Leukemia
[description not available] | 0 | 5.01 | 5 | 0 |
Bilateral Wilms Tumor
[description not available] | 0 | 4.56 | 5 | 1 |
Wilms Tumor
A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN. | 0 | 4.56 | 5 | 1 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. | 0 | 5.01 | 5 | 0 |
Infection
[description not available] | 0 | 2.15 | 1 | 0 |
Infections
Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. | 0 | 2.15 | 1 | 0 |
Angiogenesis, Pathologic
[description not available] | 0 | 2.48 | 2 | 0 |
Ewing Sarcoma
[description not available] | 0 | 2.17 | 1 | 0 |
Sarcoma, Ewing
A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females. | 0 | 2.17 | 1 | 0 |
ARSA Deficiency
[description not available] | 0 | 2.17 | 1 | 0 |
Leukodystrophy, Metachromatic
An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms. | 0 | 2.17 | 1 | 0 |
Blood Diseases
[description not available] | 0 | 3.47 | 2 | 0 |
Hematologic Diseases
Disorders of the blood and blood forming tissues. | 0 | 3.47 | 2 | 0 |
Encephalopathy, Toxic
[description not available] | 0 | 4.01 | 1 | 0 |
Endotoxemia
A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators. | 0 | 8.59 | 1 | 1 |
Benign Cerebellar Neoplasms
[description not available] | 0 | 3.01 | 1 | 0 |
Arachnoidal Cerebellar Sarcoma, Circumscribed
[description not available] | 0 | 3.01 | 1 | 0 |
Medulloblastoma
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1) | 0 | 3.01 | 1 | 0 |
Leucocythaemia
[description not available] | 0 | 4.78 | 4 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 4.78 | 4 | 0 |
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.11 | 1 | 0 |
Capillary Leak Syndrome
A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE. | 0 | 3.03 | 1 | 0 |
Injuries, Radiation
[description not available] | 0 | 3.03 | 1 | 0 |
Symptom Cluster
[description not available] | 0 | 5.43 | 5 | 0 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 4.74 | 2 | 1 |
Syndrome
A characteristic symptom complex. | 0 | 5.43 | 5 | 0 |
Phlegmasia Alba Dolens
Inflammation that is characterized by swollen, pale, and painful limb. It is usually caused by DEEP VEIN THROMBOSIS in a FEMORAL VEIN, following PARTURITION or an illness. This condition is also called milk leg or white leg. | 0 | 9.61 | 31 | 17 |
Thrombophlebitis
Inflammation of a vein associated with a blood clot (THROMBUS). | 0 | 9.61 | 31 | 17 |
Aggressive Systemic Mastocytosis
A form of systemic mastocytosis in which patients have impaired organ functions due to multifocal infiltrates of pathological MAST CELLS in bone marrow, liver, spleen, gastrointestinal tract, or skeletal system. The cytomorphology shows a low to high grade. | 0 | 2.13 | 1 | 0 |
Mastocytosis, Systemic
A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis. | 0 | 2.13 | 1 | 0 |
Rhabdomyosarcoma
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9) | 0 | 7.13 | 1 | 0 |
Disease Exacerbation
[description not available] | 0 | 2.13 | 1 | 0 |
Kidney Failure
A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. | 0 | 11.44 | 17 | 17 |
Renal Insufficiency
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | 0 | 11.44 | 17 | 17 |
Genetic Diseases
[description not available] | 0 | 3.06 | 1 | 0 |
Genetic Diseases, Inborn
Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero. | 0 | 3.06 | 1 | 0 |
Catastrophic Illness
An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly. | 0 | 4.13 | 3 | 0 |
Anti-Phospholipid Antibody Syndrome
[description not available] | 0 | 4.36 | 4 | 0 |
Antiphospholipid Syndrome
The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR). | 0 | 9.36 | 4 | 0 |
Blood Pressure, Low
[description not available] | 0 | 2.15 | 1 | 0 |
Hypotension
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients. | 0 | 2.15 | 1 | 0 |
Left Ventricular Dysfunction
[description not available] | 0 | 2.04 | 1 | 0 |
Lymphoma, T Cell, Peripheral
[description not available] | 0 | 2.04 | 1 | 0 |
Endocarditis, Loeffler
[description not available] | 0 | 2.04 | 1 | 0 |
Right Ventricular Dysfunction
[description not available] | 0 | 2.04 | 1 | 0 |
Lymphoma, T-Cell, Peripheral
A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment. | 0 | 2.04 | 1 | 0 |
Hypereosinophilic Syndrome
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. | 0 | 2.04 | 1 | 0 |
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. | 0 | 2.04 | 1 | 0 |
Marfan Syndrome, Type I
[description not available] | 0 | 2.04 | 1 | 0 |
Marfan Syndrome
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2. | 0 | 2.04 | 1 | 0 |
Carcinoma, Oat Cell
[description not available] | 0 | 3.43 | 1 | 1 |
Cancer of Lung
[description not available] | 0 | 3.86 | 2 | 1 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 3.86 | 2 | 1 |
Carcinoma, Small Cell
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 3.43 | 1 | 1 |
Myeloproliferative Disorders
Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE. | 0 | 2.05 | 1 | 0 |
Anemia, Cooley's
[description not available] | 0 | 2.05 | 1 | 0 |
beta-Thalassemia
A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. | 0 | 2.05 | 1 | 0 |
Recrudescence
[description not available] | 0 | 3.63 | 3 | 0 |
Cerebral Malaria
[description not available] | 0 | 7.48 | 2 | 0 |
Postthrombotic Syndrome
A condition caused by one or more episodes of DEEP VEIN THROMBOSIS, usually the blood clots are lodged in the legs. Clinical features include EDEMA; PAIN; aching; heaviness; and MUSCLE CRAMP in the leg. When severe leg swelling leads to skin breakdown, it is called venous STASIS ULCER. | 0 | 3.9 | 1 | 0 |
Autoimmune Disease
[description not available] | 0 | 2.07 | 1 | 0 |
Autoimmune Diseases
Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 2.07 | 1 | 0 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 2.08 | 1 | 0 |
Thrombopenia
[description not available] | 0 | 2.08 | 1 | 0 |
Thrombocytopenia
A subnormal level of BLOOD PLATELETS. | 0 | 7.08 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 2.08 | 1 | 0 |
Leg Ulcer
Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes. | 0 | 3.84 | 2 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 4.6 | 10 | 0 |
Ischemia
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. | 0 | 5.24 | 12 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 4.6 | 10 | 0 |
Diabetic Retinopathy
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 8.79 | 2 | 1 |
Granuloma Annulare
Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures. | 0 | 7.01 | 1 | 0 |
Granulocytic Leukemia
[description not available] | 0 | 2.71 | 3 | 0 |
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 2.71 | 3 | 0 |
Chronic Illness
[description not available] | 0 | 5.95 | 5 | 2 |
Deep Vein Thrombosis
[description not available] | 0 | 3.4 | 1 | 1 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 5.95 | 5 | 2 |
Venous Thrombosis
The formation or presence of a blood clot (THROMBUS) within a vein. | 0 | 3.4 | 1 | 1 |
Heart Disease, Ischemic
[description not available] | 0 | 2.69 | 3 | 0 |
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 2.69 | 3 | 0 |
B-Cell Lymphoma
[description not available] | 0 | 2.02 | 1 | 0 |
Budd-Chiari Syndrome
A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon. | 0 | 2.02 | 1 | 0 |
Lymphoma, B-Cell
A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. | 0 | 2.02 | 1 | 0 |
Arrhythmia
[description not available] | 0 | 2.41 | 2 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 7.68 | 14 | 3 |
Arrhythmias, Cardiac
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. | 0 | 2.41 | 2 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 7.68 | 14 | 3 |
Anaphylactic Reaction
[description not available] | 0 | 3.41 | 1 | 1 |
Allergy, Drug
[description not available] | 0 | 3.41 | 1 | 1 |
Anaphylaxis
An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death. | 0 | 3.41 | 1 | 1 |
Drug Hypersensitivity
Immunologically mediated adverse reactions to medicinal substances used legally or illegally. | 0 | 3.41 | 1 | 1 |
Venous Insufficiency
Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle. | 0 | 3.79 | 2 | 1 |
Albers-Schoenberg Disease
[description not available] | 0 | 3.41 | 1 | 1 |
Osteopetrosis
Excessive formation of dense trabecular bone leading to pathological fractures; OSTEITIS; SPLENOMEGALY with infarct; ANEMIA; and extramedullary hemopoiesis (HEMATOPOIESIS, EXTRAMEDULLARY). | 0 | 8.41 | 1 | 1 |
Liver Dysfunction
[description not available] | 0 | 2.03 | 1 | 0 |
Liver Diseases
Pathological processes of the LIVER. | 0 | 2.03 | 1 | 0 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 2.47 | 2 | 0 |
Cancer of Stomach
[description not available] | 0 | 2.03 | 1 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 2.47 | 2 | 0 |
Stomach Neoplasms
Tumors or cancer of the STOMACH. | 0 | 2.03 | 1 | 0 |
Enlarged Liver
[description not available] | 0 | 3.36 | 2 | 0 |
Germinoblastoma
[description not available] | 0 | 2.44 | 2 | 0 |
Lymphoma
A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 2.44 | 2 | 0 |
Icterus
[description not available] | 0 | 2.96 | 1 | 0 |
Ache
[description not available] | 0 | 3.31 | 2 | 0 |
Jaundice
A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction. | 0 | 2.96 | 1 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 3.31 | 2 | 0 |
Gasser Syndrome
[description not available] | 0 | 2.37 | 2 | 0 |
Congenital Thrombotic Thrombocytopenic Purpura
[description not available] | 0 | 5.54 | 6 | 0 |
Hemolytic-Uremic Syndrome
A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE. | 0 | 2.37 | 2 | 0 |
Purpura, Thrombotic Thrombocytopenic
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases. | 0 | 5.54 | 6 | 0 |
Injury, Myocardial Reperfusion
[description not available] | 0 | 5.23 | 12 | 0 |
Arteriosclerosis
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. | 0 | 4.84 | 13 | 0 |
Muscle Relaxation
That phase of a muscle twitch during which a muscle returns to a resting position. | 0 | 1.98 | 1 | 0 |
Arterial Obstructive Diseases
[description not available] | 0 | 6.7 | 8 | 3 |
Arterial Occlusive Diseases
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency. | 0 | 6.7 | 8 | 3 |
Intermittent Claudication
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE. | 0 | 4.98 | 3 | 3 |
Coronary Thrombosis
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION. | 0 | 3.37 | 1 | 1 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.4 | 2 | 0 |
Embolism, Pulmonary
[description not available] | 0 | 5.92 | 7 | 4 |
Brain Embolism and Thrombosis
[description not available] | 0 | 2.38 | 2 | 0 |
Pulmonary Embolism
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS. | 0 | 5.92 | 7 | 4 |
Anasarca
[description not available] | 0 | 1.98 | 1 | 0 |
Edema
Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 1.98 | 1 | 0 |
Bright Disease
A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright. | 0 | 4.33 | 2 | 2 |
Granulomatosis, Wegener's
[description not available] | 0 | 3.37 | 1 | 1 |
Glomerulonephritis
Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. | 0 | 4.33 | 2 | 2 |
Granulomatosis with Polyangiitis
A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN. | 0 | 3.37 | 1 | 1 |
Berger Disease
[description not available] | 0 | 3.37 | 1 | 1 |
Glomerulonephritis, IGA
A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE. | 0 | 3.37 | 1 | 1 |
Coronary Heart Disease
[description not available] | 0 | 7.5 | 17 | 2 |
Cold Fingers, Hereditary
[description not available] | 0 | 4.97 | 3 | 1 |
Diseases, Peripheral Vascular
[description not available] | 0 | 6.3 | 5 | 3 |
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 7.5 | 17 | 2 |
Raynaud Disease
An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress. | 0 | 4.97 | 3 | 1 |
Peripheral Vascular Diseases
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART. | 0 | 6.3 | 5 | 3 |
Left Ventricular Hypertrophy
[description not available] | 0 | 1.98 | 1 | 0 |
Blood Pressure, High
[description not available] | 0 | 2.38 | 2 | 0 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 7.38 | 2 | 0 |
Smoking Cessation
Discontinuing the habit of SMOKING. | 0 | 6.98 | 1 | 0 |
Hypertrophy, Left Ventricular
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality. | 0 | 1.98 | 1 | 0 |
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 2.68 | 3 | 0 |
Chronic Kidney Failure
[description not available] | 0 | 1.99 | 1 | 0 |
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. | 0 | 1.99 | 1 | 0 |
Cerebral Ischemia
[description not available] | 0 | 1.99 | 1 | 0 |
Brain Ischemia
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 1.99 | 1 | 0 |
Thalassemias
[description not available] | 0 | 2.91 | 1 | 0 |
Thalassemia
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. | 0 | 2.91 | 1 | 0 |
Frostbite
Damage to tissues as the result of low environmental temperatures. | 0 | 6.99 | 1 | 0 |
Diabetes Mellitus, Adult-Onset
[description not available] | 0 | 3.78 | 2 | 1 |
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 3.78 | 2 | 1 |
Pleuropericarditis
Inflammation of both the PERICARDIUM and the PLEURA. | 0 | 2 | 1 | 0 |
Granulocytic Leukemia, Chronic
[description not available] | 0 | 2 | 1 | 0 |
Cardiac Tamponade
Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse. | 0 | 2 | 1 | 0 |
Pericarditis
Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS. | 0 | 2 | 1 | 0 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. | 0 | 2 | 1 | 0 |
Breast Cancer
[description not available] | 0 | 2 | 1 | 0 |
Granuloma, Hodgkin
[description not available] | 0 | 2 | 1 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2 | 1 | 0 |
Hodgkin Disease
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen. | 0 | 2 | 1 | 0 |
Bladder Pain Syndrome
[description not available] | 0 | 2 | 1 | 0 |
Bladder Diseases
[description not available] | 0 | 2 | 1 | 0 |
Cystitis, Interstitial
A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency. | 0 | 2 | 1 | 0 |
Leukemia, Acute Monocytic
[description not available] | 0 | 2.01 | 1 | 0 |
Leukemia, Monocytic, Acute
An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES. | 0 | 2.01 | 1 | 0 |
Circulatory Collapse
[description not available] | 0 | 2.67 | 3 | 0 |
Shock
A pathological condition manifested by failure to perfuse or oxygenate vital organs. | 0 | 7.67 | 3 | 0 |
Diabetic Angiopathies
VASCULAR DISEASES that are associated with DIABETES MELLITUS. | 0 | 3.77 | 2 | 1 |
Brain Vascular Disorders
[description not available] | 0 | 3.36 | 1 | 1 |
Cerebrovascular Disorders
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others. | 0 | 3.36 | 1 | 1 |
Angor Pectoris
[description not available] | 0 | 1.98 | 1 | 0 |
Angina Pectoris
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION. | 0 | 6.98 | 1 | 0 |
Female Genital Neoplasms
[description not available] | 0 | 4.32 | 2 | 2 |
Genital Neoplasms, Female
Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE). | 0 | 4.32 | 2 | 2 |
Mesenteric Vascular Occlusion
Obstruction of the flow in the SPLANCHNIC CIRCULATION by ATHEROSCLEROSIS; EMBOLISM; THROMBOSIS; STENOSIS; TRAUMA; and compression or intrinsic pressure from adjacent tumors. Rare causes are drugs, intestinal parasites, and vascular immunoinflammatory diseases such as PERIARTERITIS NODOSA and THROMBOANGIITIS OBLITERANS. (From Juergens et al., Peripheral Vascular Diseases, 5th ed, pp295-6) | 0 | 2.38 | 2 | 0 |
Ventricular Fibrillation
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. | 0 | 3.29 | 2 | 0 |
Female Genital Diseases
[description not available] | 0 | 4.32 | 2 | 2 |
Genital Diseases, Female
Pathological processes involving the female reproductive tract (GENITALIA, FEMALE). | 0 | 4.32 | 2 | 2 |
Nephrotic Syndrome
A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction. | 0 | 3.36 | 1 | 1 |
Proteinuria
The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 3.36 | 1 | 1 |
Arteriosclerosis Obliterans
Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION. | 0 | 1.96 | 1 | 0 |
Complications, Pregnancy
[description not available] | 0 | 1.97 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 1.97 | 1 | 0 |
Thromboembolism
Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream. | 0 | 4.05 | 3 | 1 |
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 1.97 | 1 | 0 |
Buerger Disease
[description not available] | 0 | 2.37 | 2 | 0 |
Sclerosis, Systemic
[description not available] | 0 | 1.97 | 1 | 0 |
Cryoglobulinemia
A condition characterized by the presence of abnormal quantities of CRYOGLOBULINS in the blood. Upon cold exposure, these abnormal proteins precipitate into the microvasculature leading to restricted blood flow in the exposed areas. | 0 | 6.97 | 1 | 0 |
Scleroderma, Systemic
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. | 0 | 1.97 | 1 | 0 |
Hemorrhagic Shock
[description not available] | 0 | 1.97 | 1 | 0 |
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues. | 0 | 3.35 | 1 | 1 |
Malignant Hypertension
[description not available] | 0 | 1.96 | 1 | 0 |
Hypertension, Malignant
A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction. | 0 | 1.96 | 1 | 0 |
Periphlebitis
Periphlebitis is inflammation of the outer coat of a vein or of tissues surrounding the vein. | 0 | 1.97 | 1 | 0 |
Dermatoses
[description not available] | 0 | 1.97 | 1 | 0 |
Stasis Ulcer
[description not available] | 0 | 1.97 | 1 | 0 |
Phlebitis
Inflammation of a vein, often a vein in the leg. Phlebitis associated with a blood clot is called (THROMBOPHLEBITIS). | 0 | 1.97 | 1 | 0 |
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS. | 0 | 1.97 | 1 | 0 |
Varicose Ulcer
Skin breakdown or ulceration in the drainage area of a VARICOSE VEIN, usually in the leg. | 0 | 1.97 | 1 | 0 |
Cancer of the Uterus
[description not available] | 0 | 3.35 | 1 | 1 |
Varices
[description not available] | 0 | 3.35 | 1 | 1 |
Uterine Neoplasms
Tumors or cancer of the UTERUS. | 0 | 3.35 | 1 | 1 |
Varicose Veins
Enlarged and tortuous VEINS. | 0 | 3.35 | 1 | 1 |
Emesis
[description not available] | 0 | 1.96 | 1 | 0 |
Diarrhea
An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. | 0 | 1.96 | 1 | 0 |
Vomiting
The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 1.96 | 1 | 0 |
Hypertension, Renal
Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN. | 0 | 1.96 | 1 | 0 |
Bone Cancer
[description not available] | 0 | 2.05 | 1 | 0 |
Osteogenic Sarcoma
[description not available] | 0 | 2.05 | 1 | 0 |
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES. | 0 | 2.05 | 1 | 0 |
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 2.05 | 1 | 0 |