chlorambucil has been researched along with Hypertension in 7 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Those with nephrotic syndrome are usually treated with steroids initially and often followed by alkylating agents (cyclophosphamide or chlorambucil)." | 2.46 | Membranous nephropathy in children: clinical presentation and therapeutic approach. ( Menon, S; Valentini, RP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menon, S | 1 |
| Valentini, RP | 1 |
| GILL, JR | 1 |
| GEORGE, JM | 1 |
| SOLOMON, A | 1 |
| BARTTER, FC | 1 |
| Canavese, JC | 1 |
| Hagge, W | 1 |
| Dathan, JR | 1 |
| Heyworth, MF | 1 |
| MacIver, AG | 1 |
| Makker, SP | 1 |
| Heymann, W | 1 |
3 reviews available for chlorambucil and Hypertension
| Article | Year |
|---|---|
Membranous nephropathy in children: clinical presentation and therapeutic approach.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biopsy; Child; Chlorambucil; Cycl | 2010 |
[Lupus erythematosus, modern aspects (author's transl)].
Topics: Antacids; Antibodies, Antinuclear; Antigen-Antibody Complex; Azathioprine; Chlorambucil; Cyclophosph | 1977 |
[Haematuria in children. III. Treatment of glomerular diseases (author's transl)].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Glomerulonephri | 1978 |
4 other studies available for chlorambucil and Hypertension
| Article | Year |
|---|---|
HYPERALDOSTERONISM AND RENAL SODIUM LOSS REVERSED BY DRUG TREATMENT FOR MALIGNANT HYPERTENSION.
Topics: Blood Chemical Analysis; Chlorambucil; Guanethidine; Humans; Hydralazine; Hyperaldosteronism; Hypert | 1964 |
Nephrotic syndrome in chronic lymphocytic leukaemia.
Topics: Aged; Basement Membrane; Biopsy; Blood Proteins; Bone Marrow; Chlorambucil; Complement System Protei | 1974 |
[Corticotherapy in rheumatoid polyarthritis].
Topics: Adrenocorticotropic Hormone; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Betamethasone; C | 1971 |
The idiopathic nephrotic syndrome of childhood. A clinical reevaluation of 148 cases.
Topics: Adolescent; Antistreptolysin; Azathioprine; Bacteriuria; Blood Urea Nitrogen; Child; Child, Preschoo | 1974 |