| ID Source | ID |
|---|---|
| PubMed CID | 15007 |
| CHEMBL ID | 119696 |
| SCHEMBL ID | 227202 |
| MeSH ID | M0172550 |
| Synonym |
|---|
| unii-9f0i7yag34 |
| 9f0i7yag34 , |
| 4-10-00-00765 (beilstein handbook reference) |
| benzoic acid, 3,5-di-tert-butyl-4-hydroxy- |
| benzoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy- |
| 3,5-di-tert-butyl-4-hydroxybenzoic acid |
| einecs 215-823-2 |
| 3,5-bis-tert-butyl-4-hydroxybenzoic acid |
| 3,5-di-t-butyl-4-hydroxybenzoic acid |
| brn 2216948 |
| OPREA1_044717 , |
| inchi=1/c15h22o3/c1-14(2,3)10-7-9(13(17)18)8-11(12(10)16)15(4,5)6/h7-8,16h,1-6h3,(h,17,18 |
| 3,5-di-tert-butyl-4-hydroxybenzoic acid, 98% |
| AC-11916 |
| HMS1648L07 |
| 3,5-ditert-butyl-4-hydroxybenzoic acid |
| CHEMBL119696 |
| AKOS001082280 |
| 1421-49-4 |
| D2381 |
| A807856 |
| FT-0633532 |
| AE-562/43460589 |
| SCHEMBL227202 |
| AB01334268-02 |
| 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzoic acid |
| f 2 (antioxidant) |
| 2,6-di-tert-butyl-4-carboxyphenol |
| 4-carboxy-2,6-di-tert-butylphenol |
| DTXSID3061683 |
| TS-00782 |
| 3,5-bis-(1,1-dimetyletyl)-4-hydroxybenzenecarboxylic acid |
| 4-hydroxy-3,5-di(tert.-butyl)benzoic acid |
| 3,5-di-tert-butyl-4-hydroxy benzoic acid |
| 3,5-di-tert-butyl4-hydroxybenzoic acid |
| 3,5-di-tert-butyl4-hydroxy-benzoic acid |
| 3,5-di-tert.-butyl-4-hydroxybenzoic acid |
| 3,5-di-tert-butyl-4-hydroxy-benzoic acid |
| 3,5-di-t-butyl-4-hydroxy-benzoic acid |
| 4-hydroxy-3,5-di-tert-butyl benzoic acid |
| 3,5-di-tert-butyl-4-hydroxybezoic acid |
| 3,5-di-t-butyl4-hydroxybenzoic acid |
| 3,5-bis(1,1-dimethylethyl)-4-hydroxy benzoic acid |
| 3,5-di(t-butyl)-4-hydroxybenzoic acid |
| 3,5-bis(1,1-dimethyethyl)-4-hydroxybenzoic acid |
| W-108178 |
| 3,5-di-tert-butyl-4-hydroxybenzoicacid |
| 3,5-di(tert-butyl)-4-hydroxybenzoic acid |
| STR04340 |
| 3,5-di-t-butyl-4-hydroxy benzoic acid |
| mfcd00008827 |
| sr-01000597216 |
| SR-01000597216-1 |
| SY048732 |
| EN300-16635 |
| D71197 |
| Q27272465 |
| NCGC00342102-01 |
| CS-0154929 |
| Z56347242 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| AID736211 | Antidyslipidemic activity against triton WR1339-induced hyperlipidemia in rat assessed as reduction in plasma triglyceride level at 56 umol/kg, ip after 24 hrs (Rvb = 580%) | 2013 | Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8 | New multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine derivatives with antioxidant, antihyperlipidemic, and antidiabetic action. |
| AID438491 | Antioxidant activity in rat brain homogenate assessed as malondialdehyde release | 2009 | Journal of medicinal chemistry, Nov-26, Volume: 52, Issue:22 | Novel compounds designed as antistress agents. |
| AID1365821 | Antioxidant activity in rat hepatic microsomes assessed as inhibition of FeSO4-induced lipid peroxidation measured after 45 mins by spectrophotometry | 2017 | Bioorganic & medicinal chemistry letters, 11-01, Volume: 27, Issue:21 | Dual antioxidant structures with potent anti-inflammatory, hypolipidemic and cytoprotective properties. |
| AID736212 | Antidyslipidemic activity against triton WR1339-induced hyperlipidemia in rat assessed as reduction in plasma total cholesterol level at 56 umol/kg, ip after 24 hrs (Rvb = 260%) | 2013 | Journal of medicinal chemistry, Apr-25, Volume: 56, Issue:8 | New multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine derivatives with antioxidant, antihyperlipidemic, and antidiabetic action. |
| AID169468 | Comparative activity versus Dihydrodimethylbenzofurans in the CPE (Carrageenan paw edema) assay; (-) indicates the compound is inactive | 1998 | Journal of medicinal chemistry, Aug-27, Volume: 41, Issue:18 | New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position. |
| AID647625 | Antioxidant activity assessed as trolox equivalent of ABTS radical scavenging activity relative to control | 2012 | European journal of medicinal chemistry, Apr, Volume: 50 | New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Further metabolism of 3,5-di-tert-butyl-4-hydroxybenzoic acid, a major metabolite of butylated hydroxytoluene, in rats. Chemical & pharmaceutical bulletin, Volume: 39, Issue: 2 | 1991 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |