| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Overweight
A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat. | 0 | 4.56 | 2 | 2 |
Diabetes Mellitus, Adult-Onset
[description not available] | 0 | 14.61 | 37 | 22 |
Blood Pressure, High
[description not available] | 0 | 13.31 | 40 | 13 |
Weight Reduction
[description not available] | 0 | 3.64 | 1 | 1 |
Body-Weight Trajectory
A general pattern of body weight gain or loss over many years. Weight change trajectory is influenced by several determinants in children and adults. | 0 | 3.64 | 1 | 1 |
Cardiovascular Diseases
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 11.54 | 16 | 8 |
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 14.61 | 37 | 22 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 13.31 | 40 | 13 |
Obesity
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 4.56 | 2 | 2 |
Weight Gain
Increase in BODY WEIGHT over existing weight. | 0 | 3.64 | 1 | 1 |
Weight Loss
Decrease in existing BODY WEIGHT. | 0 | 3.64 | 1 | 1 |
Left Ventricular Hypertrophy
[description not available] | 0 | 3.59 | 1 | 1 |
Hypertrophy, Left Ventricular
Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality. | 0 | 3.59 | 1 | 1 |
Hypertension, Essential
[description not available] | 0 | 4.88 | 2 | 1 |
Essential Hypertension
Hypertension that occurs without known cause, or preexisting renal disease. Associated polymorphisms for a number of genes have been identified, including AGT, GNB3, and ECE1. OMIM: 145500 | 0 | 4.88 | 2 | 1 |
Diabetic Angiopathies
VASCULAR DISEASES that are associated with DIABETES MELLITUS. | 0 | 11.08 | 13 | 8 |
Apoplexy
[description not available] | 0 | 7.19 | 7 | 3 |
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 7.19 | 7 | 3 |
Complications of Diabetes Mellitus
[description not available] | 0 | 3.88 | 2 | 1 |
Vascular Diseases
Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body. | 0 | 4.78 | 2 | 1 |
Kidney Failure
A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. | 0 | 3.56 | 1 | 1 |
Albuminuria
The presence of albumin in the urine, an indicator of KIDNEY DISEASES. | 0 | 6.53 | 3 | 2 |
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues. | 0 | 4.8 | 2 | 1 |
Renal Insufficiency
Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | 0 | 3.56 | 1 | 1 |
Anterior Circulation Transient Ischemic Attack
[description not available] | 0 | 2.17 | 1 | 0 |
Ischemic Attack, Transient
Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6) | 0 | 2.17 | 1 | 0 |
Diabetic Glomerulosclerosis
[description not available] | 0 | 7.23 | 4 | 2 |
Diabetic Nephropathies
KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. | 0 | 7.23 | 4 | 2 |
Autoimmune Diabetes
[description not available] | 0 | 3 | 1 | 0 |
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 3 | 1 | 0 |
Prediabetes
[description not available] | 0 | 2.1 | 1 | 0 |
Prediabetic State
The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 2.1 | 1 | 0 |
Coronary Heart Disease
[description not available] | 0 | 3.48 | 1 | 1 |
Cardiovascular Stroke
[description not available] | 0 | 6.11 | 3 | 2 |
Alcohol Drinking
Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking. | 0 | 3.48 | 1 | 1 |
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 3.48 | 1 | 1 |
Diabetic Retinopathy
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 3.48 | 1 | 1 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 6.11 | 3 | 2 |
Fasting Hypoglycemia
HYPOGLYCEMIA expressed in the postabsorptive state, after prolonged FASTING, or an overnight fast. | 0 | 5.88 | 3 | 1 |
Chronic Kidney Failure
[description not available] | 0 | 7.05 | 3 | 2 |
Hypoglycemia
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH. | 0 | 5.88 | 3 | 1 |
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. | 0 | 7.05 | 3 | 2 |
Peripheral Arterial Diseases
[description not available] | 0 | 4.43 | 1 | 1 |
Peripheral Arterial Disease
Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less. | 0 | 4.43 | 1 | 1 |
Disease Exacerbation
[description not available] | 0 | 4.43 | 1 | 1 |
Blood Pressure, Low
[description not available] | 0 | 2.15 | 1 | 0 |
Hypotension
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients. | 0 | 2.15 | 1 | 0 |
Diseases, Metabolic
[description not available] | 0 | 2.15 | 1 | 0 |
Metabolic Diseases
Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed) | 0 | 2.15 | 1 | 0 |
Arteriosclerosis, Coronary
[description not available] | 0 | 2.96 | 1 | 0 |
Hypertension, Renal
Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN. | 0 | 4.75 | 2 | 1 |
Coronary Artery Disease
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. | 0 | 2.96 | 1 | 0 |
Cognition Disorders
Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 2.96 | 1 | 0 |
Bone Fractures
[description not available] | 0 | 4.36 | 1 | 1 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 4.36 | 1 | 1 |
Fractures, Bone
Breaks in bones. | 0 | 4.36 | 1 | 1 |
Impotence
[description not available] | 0 | 3.44 | 1 | 1 |
Erectile Dysfunction
The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction. | 0 | 3.44 | 1 | 1 |