isoproterenol has been researched along with Hypertension in 538 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured changes in forearm blood flow by plethysmography in response to acetylcholine (9 and 37 microg/min), sodium nitroprusside (200 and 800 ng/min) and the beta-receptor agonist, isoproterenol (50 and 200 ng/min) in 12 patients with essential hypertension (group EH) and in healthy volunteers with (group PFH; n = 14) and without (group NFH; n = 14) a family history of essential hypertension, before and during concomitant infusion of L-arginine (10 micromol/min)." | 9.11 | beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine. ( Ahlers, BA; Kaye, DM; Parnell, MM; Schlaich, MP, 2004) |
| " In two, randomized, placebo-controlled, 5-way crossover trials, the pulmonary effects of celiprolol 200 and 400 mg, propranolol 40 mg and atenolol 100 mg were compared in 34 asthmatic patients." | 9.06 | Celiprolol, atenolol and propranolol: a comparison of pulmonary effects in asthmatic patients. ( Applin, WJ; Brown, R; Caruso, FS; Doshan, HD; Rosenthal, RR; Slutsky, A, 1986) |
| " Exchangeable sodium, blood volume, plasma norepinephrine, renin, aldosterone, pressor responsiveness to norepinephrine, heart rate responses to isoproterenol, and lipid metabolism were studied in 15 patients with essential hypertension after 8 weeks of treatment with verapamil (348 +/- 68 (SD) mg/day)." | 9.06 | Cardiovascular effects of verapamil in essential hypertension. ( Beretta-Piccoli, C; Leonardi, L; Marone, C; Riesen, W; Städler, P; Ziegler, W, 1987) |
| "The objective of the present paper is to formulate nanostructured lipid carriers (NLCs) of a calcium channel blocker, isradipine, to enhance its oral bioavailability and prolong its antihypertensive effect apart from evaluating efficacy of the formulation in isoproterenol induced myocardial infarction in rats." | 8.12 | Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction. ( Alam, T; Ali, J; Ansari, MA; Baboota, S, 2022) |
| " Furthermore, the effects of 2-ME on blood pressure and cardiovascular remodeling in the constricted aorta (CA) rat model and on isoproterenol-induced (ISO) cardiac hypertrophy and fibrosis were examined." | 7.91 | 2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. ( Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP, 2019) |
| "1 The purpose of this study was to examine the effect of inhibition of the formation of cytochrome P450 metabolites of arachidonic acid with 1-aminobenzotriazole (ABT) on the development of hypertension and end-organ damage in spontaneously hypertensive rats (SHR) chronically treated with nitric oxide synthesis inhibitor L-NAME (SHR-L-NAME)." | 7.73 | Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME. ( Benter, IF; Canatan, H; Cojocel, C; Francis, I; Juggi, JS; Yousif, MH, 2005) |
| "Forty control rats and 40 rats with aortic stenosis left ventricular hypertrophy ([LVH] group) were randomized to receive either L-arginine (0." | 7.70 | Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve. ( Bartunek, J; Dempsey, S; Ito, N; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO, 1998) |
| "Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined." | 7.70 | Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999) |
| "Since the effects of angiotensin II receptor antagonism on arterial function in nitric oxide (NO)-deficient hypertension are unknown, we investigated the influence of losartan therapy (20 mg kg-1 day-1) on the control of arterial tone in NG-nitro-L-arginine methyl ester (L-NAME; 20 mg kg-1 day-1)-induced hypertension." | 7.70 | Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism. ( Holm, P; Hutri-Kähönen, N; Jolma, P; Kähönen, M; Kalliovalkama, J; Pörsti, I; Tolvanen, JP; Wu, X, 1999) |
| " The improved endothelium-mediated relaxation following ramipril therapy could be attributed to reduced release of cyclo-oxygenase-derived constricting factors and augmented endothelium-dependent hyperpolarization in this type of experimental hypertension." | 7.69 | Ramipril therapy improves arterial dilation in experimental hypertension. ( Hutri-Kähönen, N; Kähönen, M; Pörsti, I; Sallinen, K; Tolvanen, JP; Wu, X, 1997) |
| "Beta-adrenergic receptor-mediated relaxation of blood vessels declines in lead induced hypertension although the mechanism is unknown." | 7.69 | Reduced vascular beta-adrenergic receptors and catecholamine response in rats with lead induced hypertension. ( Chang, HR; Chen, SS; Cheng, JT; Ho, CK; Tsao, DA; Yu, HS, 1997) |
| "The effects of bucindolol a new nonselective beta blocker were studied after short-term dosing and for up to six months in eight patients with essential hypertension." | 7.67 | Bucindolol in essential hypertension. ( Curzio, J; Reid, JL; Vincent, J, 1985) |
| "The left ventricular function of 23 patients with essential hypertension was investigated during infusion of isoproterenol (ISP)." | 7.67 | [Left ventricular function in essential hypertension during isoproterenol infusion]. ( Hirota, K; Kajino, H; Kawarabayashi, T; Murai, K; Nishikimi, T; Oku, H; Takeda, T; Takeuchi, K; Yasuda, M; Yoshimura, T, 1985) |
| "The left ventricular function of patients with essential hypertension was examined during exercise and isoproterenol (ISP) infusion echocardiography." | 7.67 | Cardiac function of patients with essential hypertension during exercise and isoproterenol infusion. ( Komatsu, H; Murai, K; Nishikimi, T; Oku, H; Takeda, T; Takeuchi, K; Yasuda, M, 1987) |
| "Some metabolic consequences of experimental hypertension on rat brain capillaries and kidney glomeruli have been studied in rats made hypertensive by a combination of deoxycorticosterone acetate injection and elevated salt intake (DOCA-salt hypertension) and isoproterenol injection." | 7.67 | Aromatic L-amino acid decarboxylase, dopamine beta-hydroxylase, monoamine oxidase, malondialdehyde, and acid phosphatase in rat brain capillaries and kidney glomeruli in experimental hypertension. ( Sadasivudu, B; Valli, VV, 1985) |
| "We infused tracer-labeled l-[3H]-norepinephrine, d-[14C]norepinephrine, and d,l-[3H]-isoproterenol simultaneously into patients with essential hypertension and into normotensive control subjects, in order to determine whether abnormalities in the disappearance kinetics of these substances characterized the hypertensive patients." | 7.66 | Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension. ( Goldstein, DS; Horwitz, D; Keiser, HR; Kopin, IJ; Polinsky, RJ, 1983) |
| "Thirty-one age-matched, conscious, virgin, male Sprague-Dawley rats and spontaneously hypertensive rats (SHRs) were individually injected with a single subcutaneous dose of 85 mg/kg dl-isoproterenol to determine the degree and time course of drug-induced cardiac failure and functional recovery." | 7.66 | Isoproterenol-induced cardiac failure in the spontaneously hypertensive rat. ( Iams, SG; Yeager, JC, 1981) |
| "An in vivo study of skeletal muscle paralysis induced by intravenous barium chloride has been made in curarized and non-curarized rats." | 7.65 | Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis. ( McArdle, B; Schott, GD, 1974) |
| "Forty-five normotensive and hypertensive sleep apnea patients (respiratory disturbance index >20) and non-apneic controls." | 5.30 | The effects of hypoxia and sleep apnea on isoproterenol sensitivity. ( Ancoli-Israel, S; Clausen, J; Dimsdale, JE; Loredo, JS; Mills, PJ, 1998) |
| " Dose-response relation was obtained in terms of various doses of ISO and the increments of heart rate (deltaHR) produced by ISO." | 5.27 | Estimated affinity of isoproterenol to cardiac chronotropic beta-receptor and of phenylephrine to vasoconstrictive alpha-receptor of the systemic resistance vessels in human borderline hypertension. ( Hirakawa, S; Ito, H; Tonai, N, 1983) |
| " We have constructed isoproterenol dose-response curves in four groups of patients under general anesthesia: group I, 27 elderly normotensive patients not receiving drugs; group II, 14 hypertensive patients treated with cardioselective beta-adrenoceptor antagonists; group III, 15 hypertensive patients receiving nonselective beta-adrenoceptor antagonists; group IV, 13 patients receiving an infusion of labetalol at 0." | 5.27 | Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves. ( Dagnino, J; Prys-Roberts, C, 1985) |
| "The isoproterenol-induced increase in plasma cyclic adenosine 3':5'-monophosphate (cAMP) reflects the response of adenylate cyclase to beta-adrenergic stimulation, whereas a non-beta-receptor-mediated increase occurs with the administration of glucagon." | 5.26 | Plasma cyclic adenosine 3':5'-monophosphate response to isoproterenol and glucagon in hyperkinetic borderline (labile) hypertension. ( Fraysse, J; Genest, J; Guthrie, GP; Hamet, P; Kuchel, O; Messerli, FH; Nowaczynski, W; Tolis, G, 1976) |
| "We measured changes in forearm blood flow by plethysmography in response to acetylcholine (9 and 37 microg/min), sodium nitroprusside (200 and 800 ng/min) and the beta-receptor agonist, isoproterenol (50 and 200 ng/min) in 12 patients with essential hypertension (group EH) and in healthy volunteers with (group PFH; n = 14) and without (group NFH; n = 14) a family history of essential hypertension, before and during concomitant infusion of L-arginine (10 micromol/min)." | 5.11 | beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine. ( Ahlers, BA; Kaye, DM; Parnell, MM; Schlaich, MP, 2004) |
| "During isoflurane anesthesia, an epinephrine-containing test dose produces unreliable heart rate (HR) responses with a high incidence of hypertension, whereas an isoproterenol-containing test dose results in a high incidence of hypotension." | 5.08 | The combination of epinephrine and isoproterenol as a simulated epidural test dose in isoflurane-anesthetized adults. ( Nishikawa, T; Tanaka, M, 1998) |
| "These results show that, in humans, hypertension does not lead to a decrease in chronotropic responses to infusion of the beta-agonist isoproterenol and causes only a modest decrease in left ventricular responses." | 5.08 | Age, hypertension, and cardiac responses to beta-agonist in humans. ( Fourney, A; Leenen, FH; White, M, 1998) |
| " However, we found that the vasodilator responses to nitroprusside, acetylcholine, carbachol, and isoproterenol were also similar in separate groups of normotensive controls (n = 18) and hypertensive subjects, whether the subjects had never been treated for hypertension (n = 24) or had had therapy withheld for two weeks (n = 17)." | 5.07 | Preserved endothelium-dependent vasodilatation in patients with essential hypertension. ( Benjamin, N; Chowienczyk, PJ; Cockcroft, JR; Ritter, JM, 1994) |
| " To investigate these aspects, we assessed the cardiovascular responsiveness to norepinephrine and angiotensin II, plasma levels of catecholamines, angiotensin II, ANF and aldosterone and the body sodium-blood volume state of 15 patients with essential hypertension (mean age +/- s." | 5.07 | Modulation of noradrenergic but not angiotensinergic blood pressure control by beta-blockade with carteolol. ( Ferrier, C; Morger, D; Saxenhofer, H; Shaw, SG; Weidmann, P, 1991) |
| " In two, randomized, placebo-controlled, 5-way crossover trials, the pulmonary effects of celiprolol 200 and 400 mg, propranolol 40 mg and atenolol 100 mg were compared in 34 asthmatic patients." | 5.06 | Celiprolol, atenolol and propranolol: a comparison of pulmonary effects in asthmatic patients. ( Applin, WJ; Brown, R; Caruso, FS; Doshan, HD; Rosenthal, RR; Slutsky, A, 1986) |
| "To investigate the pathogenetic constellation and its modification by calcium channel blockade in hypertension associated with chronic nonoliguric renal failure, blood pressure (BP), various pressor factors or correlates, cardiovascular responsiveness, and plasma atrial natriuretic peptide (ANP) were assessed in 15 hypertensive patients (serum creatinine 160-715 mumol/l) before and after 6 weeks of intervention with the agent nitrendipine." | 5.06 | Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure. ( Bürgisser, E; Ferrier, C; Gnädinger, MP; Jahn, H; Schohn, D; Weidmann, P, 1989) |
| " Exchangeable sodium, blood volume, plasma norepinephrine, renin, aldosterone, pressor responsiveness to norepinephrine, heart rate responses to isoproterenol, and lipid metabolism were studied in 15 patients with essential hypertension after 8 weeks of treatment with verapamil (348 +/- 68 (SD) mg/day)." | 5.06 | Cardiovascular effects of verapamil in essential hypertension. ( Beretta-Piccoli, C; Leonardi, L; Marone, C; Riesen, W; Städler, P; Ziegler, W, 1987) |
| "The effects of metoprolol, a selective beta adrenergic receptor antagonist, on blood pressure, beta receptor blockade (antagoinst of isoproterenol and exercise tachycardia), and plasma renin activity (PRA) have been compared with those of placebo in 16 patients with essential hypertension." | 5.04 | Plasma levels and effects of metoprolol on blood pressure, adrenergic beta receptor blockade, and plasma renin activity in essential hypertension. ( Collste, P; Frisk-Holmberg, M; Haglund, K; Jorfelt, L; Orme, M; Ostman, J; Sjoqvist, F; von Bahr, C, 1976) |
| "The comparative potency of two beta-blockers, propranolol and atenolol, in the inhibition of exercise tachycardia and isoproterenol-tachycardia has been studied in two groups of hypertensive patients, using oral doses which were increased weekly." | 5.04 | Comparative potency of atenolol and propranolol as beta-adrenergic blocking agents in man. ( Amery, A; De Plaen, JF; Reybrouck, T, 1976) |
| "The objective of the present paper is to formulate nanostructured lipid carriers (NLCs) of a calcium channel blocker, isradipine, to enhance its oral bioavailability and prolong its antihypertensive effect apart from evaluating efficacy of the formulation in isoproterenol induced myocardial infarction in rats." | 4.12 | Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction. ( Alam, T; Ali, J; Ansari, MA; Baboota, S, 2022) |
| " Furthermore, the effects of 2-ME on blood pressure and cardiovascular remodeling in the constricted aorta (CA) rat model and on isoproterenol-induced (ISO) cardiac hypertrophy and fibrosis were examined." | 3.91 | 2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury. ( Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP, 2019) |
| "Lead is considered a causative factor for hypertension and other cardiovascular diseases." | 3.85 | Sub-chronic lead exposure produces β ( Alonso, MJ; Fioresi, M; Salaices, M; Simões, MR; Toscano, CM; Vassallo, DV, 2017) |
| " Physical training was considered a physiological condition, while isoproterenol-induced hypertrophy, myocardial infarction and DOCA-salt model of hypertension were used as pathological models of heart injury." | 3.78 | The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli. ( Almeida, PW; Braga, VB; Campagnole-Santos, MJ; Coutinho, DC; Dias-Peixoto, MF; Ferreira, AJ; Gomes Filho, A; Greco, L; Guatimosim, S; Lima, RF; Melo, DS; Melo, MB; Santos, RA, 2012) |
| "Plasma catecholamines and hemodynamics were examined in response to intravenous glucagon, yohimbine, and trimethaphan in 11 patients with pseudopheochromocytoma and a comparison group of nine normotensive and five hypertensive volunteers." | 3.74 | Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma. ( Bentho, O; Eisenhofer, G; Geraci, MF; Goldstein, DS; Holmes, C; Pacak, K; Pechnik, S; Saleem, A; Sharabi, Y, 2007) |
| "1 The purpose of this study was to examine the effect of inhibition of the formation of cytochrome P450 metabolites of arachidonic acid with 1-aminobenzotriazole (ABT) on the development of hypertension and end-organ damage in spontaneously hypertensive rats (SHR) chronically treated with nitric oxide synthesis inhibitor L-NAME (SHR-L-NAME)." | 3.73 | Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME. ( Benter, IF; Canatan, H; Cojocel, C; Francis, I; Juggi, JS; Yousif, MH, 2005) |
| " We also made an ex-vivo study of the changes in intracellular ionized magnesium in lymphocytes in 20 subjects with essential arterial hypertension, 10 treated with 120 mg/d of propranolol and 10 with placebo." | 3.72 | Catecholamine-induced regulation in vitro and ex vivo of intralymphocyte ionized magnesium. ( Degan, M; Delva, P; Lechi, A; Montesi, G; Pastori, C, 2004) |
| " The selective improvements produced by NAC, in systolic arterial pressure, heart rate, aortic endothelial function, ONOO- -induced impairment of endothelium-independent relaxation, aortic GSSG/GSH balance, malondialdehyde content and 3-NT formation in SHR suggest that chronic administration of NAC may have a protective effect against aortic vascular dysfunction in the SHR model of hypertension." | 3.71 | Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats. ( Besner, JG; Bouchard, JF; Cabassi, A; de Champlain, J; Dumont, EC; Girouard, H; Lamontagne, D; Le Jossec, M, 2001) |
| "To determine whether there are differences in cardiac beta-adrenoceptor responsiveness, isoprenaline affinity constants and fractional beta-adrenoceptor occupancy-response relationships for isoprenaline in the early stages of established hypertension, we studied the effects of bromoacetylalprenololmenthane (BAAM) and ([3,5-diamino-6-chloro-N-(1[N-beta-(2-hydroxyl-3-alpha-naphthoxypropy lamino)ethylcarbamoyl]-1-methylethyl)-pyrazine-2-carboxamide (ICI 147 798), slowly reversible beta-adrenoceptor antagonists, on the isoprenaline responses of the left ventricular papillary muscle and the left and right atria of 6-month-old Wistar Kyoto rats (WKY) and spontaneously hypertensive rats (SHR)." | 3.70 | Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats. ( Barnett, CW; Doggrell, SA; Petcu, EB, 1998) |
| "Forty control rats and 40 rats with aortic stenosis left ventricular hypertrophy ([LVH] group) were randomized to receive either L-arginine (0." | 3.70 | Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve. ( Bartunek, J; Dempsey, S; Ito, N; Lorell, BH; Rohrbach, S; Tajima, M; Weinberg, EO, 1998) |
| "Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined." | 3.70 | Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999) |
| "Since the effects of angiotensin II receptor antagonism on arterial function in nitric oxide (NO)-deficient hypertension are unknown, we investigated the influence of losartan therapy (20 mg kg-1 day-1) on the control of arterial tone in NG-nitro-L-arginine methyl ester (L-NAME; 20 mg kg-1 day-1)-induced hypertension." | 3.70 | Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism. ( Holm, P; Hutri-Kähönen, N; Jolma, P; Kähönen, M; Kalliovalkama, J; Pörsti, I; Tolvanen, JP; Wu, X, 1999) |
| " Using radiotelemetry for monitoring cardiovascular parameters of spontaneously hypertensive rats treated with clonidine or moxonidine, we showed that clonidine, unlike moxonidine, resulted in rebound hypertension after drug withdrawal." | 3.69 | Mechanisms of cardiac cell damage due to catecholamines: significance of drugs regulating central sympathetic outflow. ( Dhalla, KS; Dhalla, NS; Rupp, H, 1994) |
| " To investigate whether inotropic responsiveness is associated with alterations in beta-adrenergic receptors in spontaneously hypertensive rats (SHR), we studied left ventricular myocardial contractile responses to isoproterenol and beta-adrenergic receptor density and affinity in age-matched rats (18 to 24 months), including SHR without heart failure, SHR with evidence of heart failure, and normotensive control Wistar-Kyoto rats (WKY)." | 3.69 | Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure. ( Atkins, FL; Bing, OH; Brooks, WW; Conrad, CH; DiMauro, PG; Robinson, KG, 1995) |
| " This conclusion is strengthened by the observation that hypertrophic hearts from volume-overloaded rats had similar amounts of cardiac hypertrophy to the hearts from the hypertensive rats, without a change in flow, coronary vascular resistance or ischaemic sensitivity, whereas the hearts from isoproterenol-treated rats had lower ischaemic sensitivity and coronary vascular resistance." | 3.69 | Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats. ( Harmsen, E; Leenen, FH; Ruzicka, M; Schoemaker, R; Yu, J, 1994) |
| "To analyze the adrenergic responses and to compare them between hypertensive patients with and without left ventricular hypertrophy (LVH), left ventricular (LV) fractional shortening (FS) and end-systolic wall stress (ESS) were measured by echocardiography and the inotropic response to the infusion of isoproterenol (0." | 3.69 | Decreased adrenergic response in hypertensive patients without left ventricular hypertrophy. ( Fujieda, K; Iida, K; Sugishita, Y; Yukisada, K, 1994) |
| " The effect of in vitro treatment with isoproterenol (ISO), a beta-adrenergic drug, on phagocytosis and respiratory burst by splenic macrophages (SpMø) from normotensive Wistar-Kyoto rats (WKY) and SHR with established hypertension, respectively, was evaluated." | 3.69 | Beta-adrenoceptor responsiveness of splenic macrophages in normotensive and hypertensive rats. ( Jirillo, E; Mansi, G; Mitolo-Chieppa, D; Montagnani, M; Potenza, MA; Serio, M, 1996) |
| " The improved endothelium-mediated relaxation following ramipril therapy could be attributed to reduced release of cyclo-oxygenase-derived constricting factors and augmented endothelium-dependent hyperpolarization in this type of experimental hypertension." | 3.69 | Ramipril therapy improves arterial dilation in experimental hypertension. ( Hutri-Kähönen, N; Kähönen, M; Pörsti, I; Sallinen, K; Tolvanen, JP; Wu, X, 1997) |
| "Beta-adrenergic receptor-mediated relaxation of blood vessels declines in lead induced hypertension although the mechanism is unknown." | 3.69 | Reduced vascular beta-adrenergic receptors and catecholamine response in rats with lead induced hypertension. ( Chang, HR; Chen, SS; Cheng, JT; Ho, CK; Tsao, DA; Yu, HS, 1997) |
| " The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation." | 3.68 | Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991) |
| "To assess the role of the sympathetic nervous system in the development of genetic hypertension, blood pressure (BP) was recorded in conscious adult Lyon hypertensive (LH) and normotensive (LN) rats that had received daily injections of saline or guanethidine at 1-13 wk of age." | 3.68 | Blood pressure maintenance in hypertensive sympathectomized rats. I. Adrenal medullary catecholamines. ( Barres, C; Boomsma, F; Cerutti, C; Julien, C; Lo, M; Sassard, J; Vincent, M, 1991) |
| "Seven adult patients with old and severe arterial hypertension were found to have hypertrophic cardiomyopathy with left ventricular obstruction demonstrated by an isoproterenol test." | 3.68 | [Hypertrophic cardiomyopathy with left ventricular dynamic obstruction syndrome in hypertensive adult patients]. ( Boulenc, JM; Brandt, CM; Carrière, T; Imbs, JL; Verdun, A, 1991) |
| "To determine the effects of aging and concentric hypertrophy on the reserve of the left ventricle (LV), 36 patients with hypertension (HT), 22 with hypertrophic cardiomyopathy (HCM) and 25 age-matched normal subjects (N) were studied by isoproterenol (ISP) infusion echocardiography." | 3.68 | Left ventricular reserve of the hypertrophied heart in patients with systemic hypertension and hypertrophic cardiomyopathy--relation to age and left ventricular relative wall thickness. ( Chou, HT; Fukuzaki, H; Yokota, Y, 1990) |
| "To determine the contribution of altered beta-receptor function in the vasculature to the increased peripheral vascular resistance seen in hypertension, the effects of intra-arterial infusions of isoproterenol and epinephrine on forearm blood flow were determined in 11 male normotensive subjects and 11 male hypertensive subjects during 10 and 250 mmol/day sodium diets." | 3.68 | Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro. ( Merrell, WJ; Nadeau, JH; Naslund, T; Silberstein, DJ; Wood, AJ, 1990) |
| "To determine whether obesity alters responsiveness to vasoactive drugs, we compared the cardiovascular effects of angiotensin, phenylephrine and isoproterenol in unanesthetized age-matched control and obese Oscai rats." | 3.68 | Renovascular beta adrenergic hypersensitivity and hyperinsulinemia in rats with dietary-induced obesity. ( Buñag, RD; Krizsan, D; Tomita, T, 1990) |
| "To study potential cardiac receptor alterations during the development of spontaneous hypertension, specific binding of [3H]-2-N(2,6-dimethoxyphenoxyethyl)amino-methyl-1,4-benzodioxane, (-)-[3H]dihydroalprenolol and (-)-[3H]quinuclidinyl benzilate in ventricles of Wistar Kyoto rats (WKY), spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) at different ages was determined." | 3.67 | Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension. ( Hayashi, E; Hayashi, M; Ishima, T; Okada, T; Tomita, T; Yamada, S, 1984) |
| "In patients with normal-renin, mild (n = 6) or moderate (n = 6) hypertension, the antihypertensive effects of propranolol (80 mg/day) for 1 day or for 2 weeks were evaluated in relation to the degree of beta-adrenoceptor blockade induced." | 3.67 | Antihypertensive effect and degree of beta-adrenoceptor blockade after short-term and semi-chronic propranolol therapy. ( Boer, P; Dorhout Mees, EJ; Leenen, FH, 1984) |
| "Blood pressure (BP), plasma levels of norepinephrine (NE) and epinephrine, the chronotropic effect of isoproterenol, and the relationship between variations in BP and concomitant plasma NE levels obtained during NE infusion were studied under control conditions and after 10 days of dietary potassium supplementation (100 mmol/day) in 12 normotensive subjects with negative family history (FH) of hypertension (mean BP 111/70 +/- 9/7 mmHg), 11 normotensive subjects with positive FH (112/73 +/- 8/6 mmHg), and 10 subjects with untreated borderline to mild essential hypertension (131/89 +/- 15/9 mmHg)." | 3.67 | Correction of cardiovascular hypersensitivity to norepinephrine by potassium supplementation in normotensive members of hypertensive families and patients with essential hypertension. ( Beretta-Piccoli, C; Bianchetti, MG; Ferrier, C; Gerber, A; Link, L; Weidmann, P, 1984) |
| " In order to further investigate this, the body sodium-blood volume state as well as the pressor reactivity to infused Ang II or norepinephrine (NE) were assessed in 12 normal subjects and 16 patients with essential hypertension given a placebo, and after 6 weeks of intervention with enalapril (20-40 mg/day)." | 3.67 | Antihypertensive contribution of sodium depletion and the sympathetic axis during chronic angiotensin II converting enzyme inhibition. ( Ferrier, CP; Gnaedinger, MP; Matthieu, R; Reuter, K; Saxenhofer, H; Shaw, S; Uehlinger, DE; Weidmann, P, 1989) |
| "Lipid peroxidation as well as enzyme and isoenzyme activities in heart and blood plasma were investigated in 8- and 20-week-old SHR after administration of 40 mg/kg body weight isoproterenol in comparison to WKY rats in order to examine the susceptibility of the hearts of hypertensive animals towards catecholamine-induced damage." | 3.67 | Enhanced formation of lipid peroxides might contribute to the high sensitivity of spontaneously hypertensive rats towards isoproterenol-induced myocardial damage. ( Moritz, V; Papies, B; Schimke, I, 1989) |
| "To investigate the influence of heredity to the sympathetic nervous function and the cell membrane cation transport systems, we studied the blood pressure and plasma catecholamine response to supine exercise testings by bicycle ergometer, the pressure response to noradrenaline infusion tests and the heart rate response to isoproterenol infusion tests in 88 healthy Japanese sedentary normotensive men with and without a family history of essential hypertension [FHH(+) and FHH(-)]." | 3.67 | Sympathetic nervous function and erythrocyte cation transport systems in normotensive individuals with family history of hypertension. ( Inagaki, Y; Iwata, J; Kai, N; Koshibu, Y; Saito, T; Sakaguchi, A; Tonooka, M; Yamamoto, K, 1989) |
| "The effects of acute stimulation of the sympathetic activity by dynamic exercise on lymphocyte beta 2-adrenoceptor density [assessed by (-)-125iodocyanopindolol (ICYP) binding] and responsiveness [10 mumol/l isoprenaline-induced cyclic adenosine monophosphate (cAMP) increases] were studied in 10 normotensive (Pdiast < 90 mmHg) volunteers and in 10 patients with established essential hypertension (Pdiast > 95 mmHg)." | 3.67 | Acute regulation of lymphocyte beta 2-adrenoceptors is altered in patients with essential hypertension. ( Bock, KD; Brodde, OE; Daul, AE; O'Hara, N; Wang, XL, 1985) |
| "The effects of bucindolol a new nonselective beta blocker were studied after short-term dosing and for up to six months in eight patients with essential hypertension." | 3.67 | Bucindolol in essential hypertension. ( Curzio, J; Reid, JL; Vincent, J, 1985) |
| "The effects of selective alpha 1-adrenergic blockade with terazosin on blood pressure and cardiovascular pressor responsiveness were assessed in 17 subjects with mild to moderate essential hypertension (mean age, 48 +/- 2 [SEM] years)." | 3.67 | Alpha 1-adrenergic blockade and cardiovascular pressor responses in essential hypertension. ( Beretta-Piccoli, C; Ferrier, C; Weidmann, P, 1986) |
| "The left ventricular function of 23 patients with essential hypertension was investigated during infusion of isoproterenol (ISP)." | 3.67 | [Left ventricular function in essential hypertension during isoproterenol infusion]. ( Hirota, K; Kajino, H; Kawarabayashi, T; Murai, K; Nishikimi, T; Oku, H; Takeda, T; Takeuchi, K; Yasuda, M; Yoshimura, T, 1985) |
| "The left ventricular function of patients with essential hypertension was examined during exercise and isoproterenol (ISP) infusion echocardiography." | 3.67 | Cardiac function of patients with essential hypertension during exercise and isoproterenol infusion. ( Komatsu, H; Murai, K; Nishikimi, T; Oku, H; Takeda, T; Takeuchi, K; Yasuda, M, 1987) |
| "The effects of 2 calcium antagonist drugs, verapamil and nifedipine, on blood pressure, heart rate (HR), plasma catecholamines, plasma renin activity and some echocardiographic indexes of left ventricular anatomy and function were studied in 67 patients with essential hypertension." | 3.67 | Adrenergic activity and left ventricular function during treatment of essential hypertension with calcium antagonists. ( Agabiti-Rosei, E; Beschi, M; Castellano, M; Muiesan, G; Muiesan, ML; Romanelli, G, 1986) |
| " The potency and efficacy of isoproterenol (ISO) in these arteries were decreased in SHR before and during the development of hypertension as compared with age-matched Wistar Kyoto rats (WKY)." | 3.67 | Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension. ( Aoki, K; Asano, M; Dohi, Y; Fujimoto, S; Matsuda, T, 1987) |
| "Some metabolic consequences of experimental hypertension on rat brain capillaries and kidney glomeruli have been studied in rats made hypertensive by a combination of deoxycorticosterone acetate injection and elevated salt intake (DOCA-salt hypertension) and isoproterenol injection." | 3.67 | Aromatic L-amino acid decarboxylase, dopamine beta-hydroxylase, monoamine oxidase, malondialdehyde, and acid phosphatase in rat brain capillaries and kidney glomeruli in experimental hypertension. ( Sadasivudu, B; Valli, VV, 1985) |
| " To verify whether or not this is due to reduction in alpha-blocking activity, phenylephrine-induced increase in blood pressure was studied in six subjects with mild essential hypertension before and after 3 and 6 days and 1 and 6 mo of continuous treatment with 200 mg labetalol three times a day by mouth." | 3.66 | Alpha-adrenoceptor blockade by labetalol during long-term dosing. ( Hlede, M; Morandin, F; Pessina, AC; Rossi, GP; Semplicini, A, 1983) |
| "6) activity were studied in hypertrophic heart of spontaneously hypertensive rats as well as in the heart of Wistar rats during the development and regression of cardiac hypertrophy induced by isoproterenol administration." | 3.66 | Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. ( Desiderio, MA; Perin, A; Sessa, A, 1983) |
| "Studies on the rats with genetically-controlled hypertension (spontaneously hypertensive rats, SHR) in which myocardiopathy had been produced by isoproterenol (ISP) administration (2 X 80 mg/kg sc daily for two days) have shown that the myocardiopathy results in a fall of the activity of adenylate cyclase (AC) lasting from the second to the fourth day after administration of ISP, while the activity of phosphodiesterase (PDE) remained unchanged." | 3.66 | The activity of adenylate cyclase and phosphodiesterase in the isoproterenol-damaged cardiac muscle of spontaneously hypertensive rats. ( Piekarska, T, 1983) |
| "We infused tracer-labeled l-[3H]-norepinephrine, d-[14C]norepinephrine, and d,l-[3H]-isoproterenol simultaneously into patients with essential hypertension and into normotensive control subjects, in order to determine whether abnormalities in the disappearance kinetics of these substances characterized the hypertensive patients." | 3.66 | Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension. ( Goldstein, DS; Horwitz, D; Keiser, HR; Kopin, IJ; Polinsky, RJ, 1983) |
| " The effects of 3 wk of treatment with two selective beta 1 blockers, metoprolol and atenolol, were observed in 54 patients with mild or moderate essential hypertension." | 3.66 | Predictability of antihypertensive efficacy of selective beta 1 blockers. ( Condorelli, M; Cuocolo, A; De Luca, N; Ricciardelli, B; Trimarco, B; Veniero, AM; Volpe, M, 1983) |
| "01) in either 11 control or 10 animals injected with isoproterenol and experiencing transient hypotension." | 3.66 | Cardiovascular injury from blunt thoracic impact of epinephrine and isoproterenol injected rabbits. ( Viano, DC, 1983) |
| "Male and female, normotensive, Sprague-Dawley (S-D) rats, and spontaneously hypertensive rats (SHR) were subjected to acute and massive myocardial infarction with isoproterenol." | 3.66 | Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats. ( McMurtry, JP; Wexler, BC, 1983) |
| "To determine if alterations in adrenergic activity precede hypertension, we evaluated the pressor effect of an alpha agonist (phenylephrine) and the chronotropic effect of a beta agonist (isoproterenol) in prehypertensive young men." | 3.66 | Adrenergic responsiveness in prehypertensive subjects. ( Guthrie, GP; Kotchen, JM; Kotchen, TA; McKean, H, 1982) |
| "Myocardial necrosis was produced in rats by injection of isoproterenol (80 mg per kg body weight)." | 3.66 | Changes of lipid peroxides and alpha-tocopherol in rats with experimentally induced myocardial necrosis. ( Higuchi, Y, 1982) |
| "Plasma catecholamines and cardiovascular responses to upright posture, exogenous noradrenaline (NA), and isoproterenol (IP) were examined in 20 young men with borderline hypertension and in 10 age-matched normotensive volunteers." | 3.66 | Elevated plasma catecholamines without alteration in cardiovascular responsiveness in young men with borderline hypertension. ( Abe, I; Fukiyama, K; Kawano, Y; Omae, T; Takeya, Y, 1982) |
| "Thirty-one age-matched, conscious, virgin, male Sprague-Dawley rats and spontaneously hypertensive rats (SHRs) were individually injected with a single subcutaneous dose of 85 mg/kg dl-isoproterenol to determine the degree and time course of drug-induced cardiac failure and functional recovery." | 3.66 | Isoproterenol-induced cardiac failure in the spontaneously hypertensive rat. ( Iams, SG; Yeager, JC, 1981) |
| "The influence of two beta-adrenoceptor antagonists, propranolol and pindolol, on the haemodynamic effects of papaverine, isoprenaline and noradrenaline was investigated in 9 male patients with first degree essential hypertension." | 3.66 | Influence of propranolol and pindolol on the haemodynamic effects of papaverine, isoprenaline and noradrenaline in hypertensive patients. ( Chu, D; Cocco, G; Haeusler, G; Schweda, E; Strozzi, C, 1980) |
| "1 The pharmacological and therapeutic effects of labetalol were investigated during an 8 h interdose period of chronic oral therapy in six patients with essential hypertension." | 3.66 | Interdose control of beta-blockade and arterial blood pressure during chronic oral labetalol treatment. ( Murray, A; Rawlins, MD; Sanders, GL, 1979) |
| "Peripheral beta-adrenergic receptor sensitivity was characterized in 24 patients with essential hypertension and in 13 age-matched normotensive subjects using an isoproterenol hydrochloride bolus dose-response technique." | 3.66 | Peripheral beta-receptor responsiveness in patients with essential hypertension. ( Dominic, JA; Guthrie, GP; Kotchen, TA; Love, DW; McAllister, RG, 1979) |
| " Acute stimulation of renin release by isoprenaline, tilting, or diazoxide in 13 normotensive individuals and in 9 patients with essential hypertension increased active plasma-renin and reduced inactive plasma-renin." | 3.65 | Inactive renin in human plasma. ( Derkx, FH; Man in 't Veld, AJ; Schalekamp, MA; Verhoeven, RP; von Gool, JM; Wenting, GJ, 1976) |
| "Notable acute improvement in pulmonary function in the majority of 32 patients with known bronchial asthma followed two inhalations of Isoproterenol." | 3.65 | Isoproterenol aerosols. ( Ishikawa, S; Segal, MS, 1975) |
| " Cardiomegaly has been produced in rats by sideropenic anaemia, by isoprenaline or thyroxine or by the application of both drugs, by artificial increase in resistance to blood flow and by long-term adaptation to hypoxia and physical stress." | 3.65 | The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly. ( Bartosová, D; Chvapil, M; Korecký, B; Poupa, O; Rakusan, K; Turek, Z; Vízek, M, 1969) |
| "An in vivo study of skeletal muscle paralysis induced by intravenous barium chloride has been made in curarized and non-curarized rats." | 3.65 | Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis. ( McArdle, B; Schott, GD, 1974) |
| "Co-dergocrine has recently been demonstrated acutely to lower plasma norepinephrine (NE) and blood pressure (BP) in patients with essential hypertension, and similar results have been obtained during chronic administration of co-dergocrine to healthy men." | 2.66 | Cardiovascular regulation and lipoprotein profile during administration of co-dergocrine in essential hypertension. ( Gnaedinger, MP; Uehlinger, DE; Weidmann, P, 1989) |
| " Tapering propranolol dosage is frequently used in the hope of preventing adverse withdrawal events but the success of such a maneuver has not been shown." | 2.65 | Prevention of propranolol withdrawal mechanism by prolonged small dose propranolol schedule. ( Lutterodt, A; Nattel, S; Rangno, RE, 1982) |
| "Labetalol was administered to six hypertensive subjects in increasing doses for seven days." | 2.64 | Hemodynamic effects of labetalol, an alpha and beta adrenergic blocking agent, in hypertensive subjects. ( Cohn, JN; Mehta, J, 1977) |
| " Dose-response curves of isoprenaline were constructed in nine hypertensive patients before and after either propranolol or metoprolol." | 2.64 | Effect of selective and non-selective beta-adrenoreceptor blockade on calf blood flow in hypertensive patients. ( Clement, DL, 1978) |
| "Hypertension affects about 5% of western populations and in the majority of cases it is of unknown aetiology." | 2.41 | Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts. ( Dalton, GR; Evans, SJ; Levi, AJ, 2000) |
| "Labetalol was 6-10 times less potent than phentolamine in blocking alpha-adrenoreceptors and 1." | 2.35 | A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. ( Brittain, RT; Levy, GP, 1976) |
| "However, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively." | 1.62 | Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. ( Gajo, B; Harasim-Symbor, E; Kasacka, I; Malinowska, B; Pędzińska-Betiuk, A; Schlicker, E; Toczek, M; Weresa, J, 2021) |
| "Hypertension is a major cause of left ventricular (LV) diastolic dysfunction." | 1.48 | Limited Impact of β-Adrenergic Receptor Activation on Left Ventricular Diastolic Function in Rat Models of Hypertensive Heart Disease. ( Bamaiyi, AJ; Mojiminiyi, FB; Norman, G; Norton, GR; Peterson, V; Woodiwiss, AJ, 2018) |
| "Hypertension is associated with unfavorable changes in adrenergic receptor responsiveness, but the relationship of race and sex to adrenergic receptor responsiveness in the development of cardiovascular disease is unclear." | 1.46 | Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure. ( Blumenthal, JA; Hill, LK; Hinderliter, AL; Johnson, KS; Sherwood, A, 2017) |
| "Leptin is a circulating adipocyte-derived hormone that influences blood pressure (BP) and metabolism." | 1.36 | Leptin reduces plasma ANP level via nitric oxide-dependent mechanism. ( Gao, S; Kim, SH; Kim, SY; Kim, SZ; Park, BH; Shah, A; Yu, J; Yuan, K, 2010) |
| " Dose-response curves were constructed for dopamine and isoprenaline that induced falls or increases in renal blood flow, respectively." | 1.35 | Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats. ( Abdulla, MH; Abdullah, NA; Anand Swarup, KR; Hazim, AI; Johns, EJ; Khan, MA; Rathore, HA; Sattar, MA, 2008) |
| "Approximately 40% of patients with type 2 diabetes present with concurrent hypertension at the time of diabetes diagnosis." | 1.35 | Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. ( Behnke, BJ; Delp, MD; Donato, AJ; Laughlin, MH; Lesniewski, LA; Ray, CA; Woodman, CR, 2008) |
| "Bisoprolol was more potent against isoprenaline, T-0509 and procaterol on the SHR than WKY rat right atrium." | 1.31 | Functional beta1- and beta2-adrenoceptors in the left and right atrium of pre-hypertensive rats. ( Doggrell, SA, 2002) |
| "In conclusion, left ventricular hypertrophy in young essential hypertensives is associated to a reduced beta2-adrenoceptor density and function, probably as a compensating mechanism of the hypertrophied myocardiocyte secondary to the increased sympathetic outflow." | 1.31 | Beta-adrenergic receptor density and function in left ventricular hypertrophy in young essential hypertensives. ( Azqueta, M; Calls, J; Cases, A; Esforzado, N; Jimenez, W; Lario, S; Paré, JC; Rivera-Fillat, F, 2000) |
| " Dose-response curves to acetylcholine and isoproterenol were carried out in absence and presence of the NO synthesis inhibitor NG-nitro-L-arginine methyl ester (LNAME), the inhibitor of the cyclo-oxygenase, indomethacin and KCI." | 1.31 | Relevance of endothelium-derived hyperpolarizing factor in the effects of hypertension on rat coronary relaxations. ( Cachofeiro, V; Cediel, E; de las Heras, N; Lahera, V; Navarro-Cid, J; Ruilope, LM; Sanz-Rosa, D; Vázquez-Pérez, S, 2001) |
| "TGR rats showed left ventricular hypertrophy (54%), higher blood pressures (76 mmHg), and elevated plasma renin activity (seven-fold) compared to controls (P < 0." | 1.31 | Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension. ( Bartel, S; Bohlender, J; Günther, J; Hempel, P; Hildenbrand, U; Krause, EG; Luft, FC; Schlegel, WP; Wagner, KD, 2001) |
| "SOP." | 1.30 | Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart. ( Brodde, OE; Heinroth-Hoffmann, I; Kotchi Kotchi, E; Osten, B; Preiss, M; Röhnert, P; Weisselberg, T, 1998) |
| "Forty-five normotensive and hypertensive sleep apnea patients (respiratory disturbance index >20) and non-apneic controls." | 1.30 | The effects of hypoxia and sleep apnea on isoproterenol sensitivity. ( Ancoli-Israel, S; Clausen, J; Dimsdale, JE; Loredo, JS; Mills, PJ, 1998) |
| " The study was undertaken to compare the beta-adrenoceptor-mediated facilitation of noradrenaline release in the tail artery of vehicle-treated rats and of rats rendered hypertensive by chronic administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX)." | 1.29 | Hypertension and enhanced beta-adrenoceptor-mediated facilitation of noradrenaline release produced by chronic blockade of adenosine receptors. ( Albino-Teixeira, A; Guimarães, S; Paiva, MQ, 1995) |
| "The findings indicate that sleep apnea is associated with a diminished beta 2-adrenergic receptor function but no change in postreceptor components and suggest a mechanism for the high comorbidity between sleep apnea and hypertension." | 1.29 | Beta 2-adrenergic receptor characteristics in sleep apnea patients. ( Ancoli-Israel, S; Clausen, JL; Coy, TV; Dimsdale, JE; Mills, PJ; Nelesen, RA, 1995) |
| "There were differences between the cardiac hypertrophy and noncardiac hypertrophy groups with regard to the pressor response to exercise and noradrenaline (i." | 1.29 | Cardiovascular response and red cell membrane sodium transport in hypertensive cardiac hypertrophy. ( Deguchi, F; Inagaki, Y; Iwata, J; Kai, N; Saito, T; Yamamoto, K, 1993) |
| "Treatment with hydralazine significantly lowered arterial pressure in SHR and WKY rats, but did not alter the enhanced contraction to phenylephrine or the enhanced relaxation to acetylcholine and nitroprusside in coronary arteris from SHR." | 1.29 | Characterization of endothelium-dependent vasodilation and vasoconstriction in coronary arteries from spontaneously hypertensive rats. ( Fuchs, LC; Johnson, AK; Lamping, KG; Nuno, D, 1996) |
| "Oral treatment with imidapril (10 mg/kg/d), an ACE inhibitor, 1 h before each ISO treatment and on the following 6 d, improved ventricular hypertrophy, the elevation of the left ventricular end diastolic pressure, the reduction in contractility, and the prolongation of the time constant." | 1.29 | Induction of cardiac angiotensinogen mRNA and angiotensin converting enzyme (ACE) activity in isoproterenol-induced heart injury. ( Ishida, R; Ogiku, N; Saeki, K; Sugiura, M, 1996) |
| " isoproterenol tachycardia dose-response curves by dose ratios of 5, 18, and 90 in sham rabbits, respectively, and 5, 11, and 23 in wrap rabbits, respectively, indicating significant cardiac beta 1-adrenoceptor antagonism." | 1.28 | Relationship between the sympatholytic action of nebivolol and hypotension. ( Angus, JA; Coles, P; Cox, H; Eisenhofer, G; Ward, JE, 1992) |
| "Cardiac hypertrophy is characterized by marked abnormalities in the contraction/relaxation pattern of the heart." | 1.28 | Isolated myocardial cells: a new tool for the investigation of hypertensive heart disease. ( Neyses, L; Vetter, H, 1990) |
| "Hypertensive cardiac hypertrophy of 20 patients was classified as inappropriate hypertrophy (HH-I) and appropriate hypertrophy (HH-II) according to their end-systolic wall stress, as measured by echocardiography." | 1.28 | Diastolic properties of hypertrophied hearts in essential hypertension: classification by left ventricular wall stress. ( Fujieda, K; Iida, K; Ito, I; Sugishita, Y; Yukisada, K, 1990) |
| " Isoproterenol stimulated cyclic adenosine monophosphate (cAMP) production in a dose-dependent manner, and dose-response experiments revealed an effective concentration of ligand at which 50% of the maximum effect is observed (EC50) of 5-10 x 10(-8) mol/l isoproterenol for both WKY and SHR." | 1.28 | Beta-adrenergic receptor differences in cultured arterial smooth muscle cells between spontaneously hypertensive and Wistar-Kyoto rats. ( Jazayeri, A; Meyer, WJ, 1989) |
| " Doses were calculated to produce plasma levels approximating those achieved after oral dosing (0." | 1.28 | Effects of dilevalol on forearm circulation in essential hypertension. ( Cleroux, J; Giannattasio, C; Grassi, G; Mancia, G; Seravalle, G; Zanchetti, A, 1989) |
| " Alpha-adrenergic responsiveness was estimated with DPD15 (the dosage of neosynephrine required for an increase of diastolic pressure of 15mmHg); beta-adrenergic responsiveness with CD25 (the dosage of isoproterenol required for an increase of heart rate of 25 beats/minute)." | 1.28 | Hyperkinetic hemodynamic pattern in some borderline hypertension: differential responses to alpha and beta agonists. ( Fan, J; Yang, Q; Yi, G, 1989) |
| " Cumulative dose-response curves of plasma cyclic AMP concentration obtained in another group of rats after successive subcutaneous injections of isoproterenol showed that the ED50 value of this drug was higher in SHR than in WKY and increased in a parallel manner in the two strains between 7 and 18 weeks of age (respectively from 0." | 1.27 | Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats. ( Bucher, B; Heitz, C; Stoclet, JC, 1984) |
| " Dose-response relation was obtained in terms of various doses of ISO and the increments of heart rate (deltaHR) produced by ISO." | 1.27 | Estimated affinity of isoproterenol to cardiac chronotropic beta-receptor and of phenylephrine to vasoconstrictive alpha-receptor of the systemic resistance vessels in human borderline hypertension. ( Hirakawa, S; Ito, H; Tonai, N, 1983) |
| " Pressor responsiveness was evaluated acutely on the basis of dose-response curves (0." | 1.27 | Pressor responses of rats to vasopressin: effect of sodium, angiotensin, and catecholamines. ( Brunner, HR; Burnier, M, 1983) |
| " We have constructed isoproterenol dose-response curves in four groups of patients under general anesthesia: group I, 27 elderly normotensive patients not receiving drugs; group II, 14 hypertensive patients treated with cardioselective beta-adrenoceptor antagonists; group III, 15 hypertensive patients receiving nonselective beta-adrenoceptor antagonists; group IV, 13 patients receiving an infusion of labetalol at 0." | 1.27 | Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves. ( Dagnino, J; Prys-Roberts, C, 1985) |
| " PRA activity was significantly and markedly reduced by both bunolol and metoprolol shortly after dosing at a time when HR was significantly reduced but MBP was not." | 1.27 | Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function. ( Antonaccio, MJ; DeForrest, JM; High, J; Sybertz, E, 1986) |
| "The antihypertensive effect of chronic administration of L-tyrosine (Tyr) was investigated in a two-part study." | 1.27 | Physiologic responses to chronic dietary tyrosine supplementation in DOCA-salt-treated rats. ( Fregly, MJ; Hathaway, S; Henley, WN; Wilson, KM, 1986) |
| " Dose-response curves in low Ca2+ (0." | 1.27 | Extracellular calcium and altered vascular responsiveness in the deoxycorticosterone acetate-salt rat. ( Field, FP; Soltis, EE, 1986) |
| "Pretreatment with desipramine decreased significantly the removal of NE to virtually exactly that of ISO." | 1.27 | Measurement of regional neuronal removal of norepinephrine in man. ( Folio, J; Goldstein, DS; Keiser, HR; Kopin, IJ; Levinson, PD; Stull, R; Zimlichman, R, 1985) |
| " Full dose-response curves for isoproterenol were constructed in BP and HR." | 1.26 | The ratio of cardiac to vascular beta-receptor blockade of atenolol and propranolol in spontaneously hypertensive rats in vivo. ( Kudo, Y; Sokabe, H, 1982) |
| "Pindolol do not lower PRA in normotensive rats but increases levels of PRA in spontaneously hypertensive rats." | 1.26 | [Action of 3-beta adrenolytics on plasma renin activity measured by radioimmunology in genetically hypertensive rats]. ( Lacroix, P; Le Pollés, JB; Linée, P; Pape, D; Van den Driessche, J, 1977) |
| "The isoproterenol-induced increase in plasma cyclic adenosine 3':5'-monophosphate (cAMP) reflects the response of adenylate cyclase to beta-adrenergic stimulation, whereas a non-beta-receptor-mediated increase occurs with the administration of glucagon." | 1.26 | Plasma cyclic adenosine 3':5'-monophosphate response to isoproterenol and glucagon in hyperkinetic borderline (labile) hypertension. ( Fraysse, J; Genest, J; Guthrie, GP; Hamet, P; Kuchel, O; Messerli, FH; Nowaczynski, W; Tolis, G, 1976) |
| "Hypertension was not obviously associated with hyperfunction of the thyroid gland." | 1.26 | Role of the thyroid gland in the development and maintenance of spontaneous hypertension in rats. ( Berkowitz, BA; Rioux, F, 1977) |
| "Thus, hypertension is not the result of an absence of beta receptor or a hypersensitivity of the vascular smooth muscle." | 1.25 | Vascular smooth muscle reactivity in normotensive and hypertensive rats. ( Brodie, BB; Fleisch, JH; Maling, HM; Spector, S, 1969) |
| " At dose-levels causing effective blockade of beta-receptors propranolol and MJ 1999 had no hypotensive effect after short- or long-term administration to conscious hypertensive rats and dogs." | 1.25 | A comparison of some cardiovascular properties of propranolol, MJ 1999 and quinidine in relation to their effects in hypertensive animals. ( Farmer, JB; Levy, GP, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 319 (59.29) | 18.7374 |
| 1990's | 123 (22.86) | 18.2507 |
| 2000's | 65 (12.08) | 29.6817 |
| 2010's | 23 (4.28) | 24.3611 |
| 2020's | 8 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Alegre, KO | 1 |
| Paknejad, N | 1 |
| Su, M | 1 |
| Lou, JS | 1 |
| Huang, J | 1 |
| Jordan, KD | 1 |
| Eng, ET | 1 |
| Meyerson, JR | 1 |
| Hite, RK | 1 |
| Huang, XY | 1 |
| Wahid, M | 1 |
| Saqib, F | 1 |
| Chicea, L | 1 |
| Ahmedah, HT | 1 |
| Sajer, BH | 1 |
| Marc Vlaic, RA | 1 |
| Pop, OL | 1 |
| Moga, M | 1 |
| Gavris, C | 1 |
| Souza Bomfim, GH | 1 |
| Musial, DC | 1 |
| Rocha, K | 1 |
| Jurkiewicz, A | 1 |
| Jurkiewicz, NH | 1 |
| Gattoni, C | 1 |
| Conti, E | 1 |
| Casolo, A | 1 |
| Nuccio, S | 1 |
| Baglieri, C | 1 |
| Capelli, C | 1 |
| Girardi, M | 1 |
| van der Horst, J | 1 |
| Rognant, S | 1 |
| Hellsten, Y | 1 |
| Aalkjær, C | 1 |
| Jepps, TA | 2 |
| Valovič, P | 1 |
| Behuliak, M | 2 |
| Vaněčková, I | 1 |
| Zicha, J | 2 |
| Thorsdottir, D | 1 |
| Cruickshank, NC | 1 |
| Einwag, Z | 1 |
| Hennig, GW | 1 |
| Erdos, B | 1 |
| Pędzińska-Betiuk, A | 1 |
| Weresa, J | 1 |
| Schlicker, E | 1 |
| Harasim-Symbor, E | 1 |
| Toczek, M | 1 |
| Kasacka, I | 1 |
| Gajo, B | 1 |
| Malinowska, B | 1 |
| Zhu, JX | 1 |
| Ling, W | 1 |
| Xue, C | 1 |
| Zhou, Z | 1 |
| Zhang, YS | 1 |
| Yan, C | 1 |
| Wu, MP | 1 |
| Alam, T | 1 |
| Ansari, MA | 1 |
| Baboota, S | 1 |
| Ali, J | 1 |
| Toscano, CM | 1 |
| Simões, MR | 1 |
| Alonso, MJ | 1 |
| Salaices, M | 3 |
| Vassallo, DV | 1 |
| Fioresi, M | 1 |
| Bamaiyi, AJ | 1 |
| Norton, GR | 6 |
| Peterson, V | 1 |
| Norman, G | 1 |
| Mojiminiyi, FB | 1 |
| Woodiwiss, AJ | 6 |
| Salah, E | 1 |
| Bastacky, SI | 1 |
| Jackson, EK | 4 |
| Tofovic, SP | 1 |
| Pintérová, M | 1 |
| Kuneš, J | 1 |
| Almeida, FR | 1 |
| Perry, JC | 1 |
| Futuro-Neto, HA | 1 |
| Almeida, VR | 1 |
| Sebastião, RM | 1 |
| Andersen, ML | 1 |
| Tufik, S | 1 |
| Campos, RR | 1 |
| Bergamaschi, CT | 1 |
| İlhan, S | 1 |
| Yılmaz, N | 1 |
| Nacar, E | 1 |
| Motor, S | 1 |
| Oktar, S | 1 |
| Şahna, E | 1 |
| Furuhashi, M | 1 |
| Mita, T | 1 |
| Moniwa, N | 1 |
| Hoshina, K | 1 |
| Ishimura, S | 1 |
| Fuseya, T | 1 |
| Watanabe, Y | 1 |
| Yoshida, H | 1 |
| Shimamoto, K | 1 |
| Miura, T | 1 |
| Deschodt-Arsac, V | 1 |
| Arsac, L | 1 |
| Magat, J | 1 |
| Naulin, J | 1 |
| Quesson, B | 1 |
| Dos Santos, P | 1 |
| Chaudagar, KK | 1 |
| Viczenczova, C | 1 |
| Szeiffova Bacova, B | 1 |
| Egan Benova, T | 1 |
| Barancik, M | 1 |
| Tribulova, N | 1 |
| Koch, SE | 1 |
| Mann, A | 1 |
| Jones, S | 1 |
| Robbins, N | 1 |
| Alkhattabi, A | 1 |
| Worley, MC | 1 |
| Gao, X | 1 |
| Lasko-Roiniotis, VM | 1 |
| Karani, R | 1 |
| Fulford, L | 1 |
| Jiang, M | 1 |
| Nieman, M | 1 |
| Lorenz, JN | 1 |
| Rubinstein, J | 1 |
| Sherwood, A | 3 |
| Hill, LK | 1 |
| Blumenthal, JA | 1 |
| Johnson, KS | 1 |
| Hinderliter, AL | 3 |
| Angelone, T | 1 |
| Quintieri, AM | 1 |
| Brar, BK | 1 |
| Limchaiyawat, PT | 1 |
| Tota, B | 1 |
| Mahata, SK | 1 |
| Cerra, MC | 1 |
| Abdulla, MH | 1 |
| Sattar, MA | 1 |
| Abdullah, NA | 1 |
| Hazim, AI | 1 |
| Anand Swarup, KR | 1 |
| Rathore, HA | 1 |
| Khan, MA | 1 |
| Johns, EJ | 1 |
| Yuan, K | 2 |
| Jin, X | 1 |
| Park, WH | 1 |
| Kim, JH | 1 |
| Park, BH | 2 |
| Kim, SH | 2 |
| Maier, T | 1 |
| Schreckenberg, R | 1 |
| Schlüter, KD | 1 |
| Falcão-Pires, I | 1 |
| Gonçalves, N | 1 |
| Moura, C | 1 |
| Lamego, I | 1 |
| Eloy, C | 1 |
| Lopes, JM | 1 |
| Begieneman, MP | 1 |
| Niessen, HW | 1 |
| Areias, JC | 1 |
| Leite-Moreira, AF | 1 |
| Yu, J | 3 |
| Shah, A | 1 |
| Gao, S | 1 |
| Kim, SY | 1 |
| Kim, SZ | 1 |
| Watkins, AJ | 1 |
| Lucas, ES | 1 |
| Torrens, C | 1 |
| Cleal, JK | 1 |
| Green, L | 1 |
| Osmond, C | 1 |
| Eckert, JJ | 1 |
| Gray, WP | 1 |
| Hanson, MA | 1 |
| Fleming, TP | 1 |
| Izzo, R | 1 |
| Cipolletta, E | 2 |
| Ciccarelli, M | 2 |
| Campanile, A | 2 |
| Santulli, G | 2 |
| Palumbo, G | 1 |
| Vasta, A | 1 |
| Formisano, S | 1 |
| Trimarco, B | 8 |
| Iaccarino, G | 2 |
| Veliotes, DG | 3 |
| Correia, RJ | 1 |
| Strijdom, H | 1 |
| Badenhorst, D | 3 |
| Brooksbank, R | 2 |
| Kim, BH | 1 |
| Akoh, CC | 1 |
| Lee, BY | 1 |
| Asdaq, SM | 1 |
| Inamdar, MN | 1 |
| Cheng, D | 1 |
| Ren, J | 1 |
| Gillespie, DG | 2 |
| Mi, Z | 3 |
| Bucher, B | 2 |
| Heitz, C | 2 |
| Stoclet, JC | 3 |
| Zhao, G | 1 |
| Walsh, E | 1 |
| Shryock, JC | 1 |
| Messina, E | 1 |
| Wu, Y | 1 |
| Zeng, D | 1 |
| Xu, X | 1 |
| Ochoa, M | 1 |
| Baker, SP | 1 |
| Hintze, TH | 1 |
| Belardinelli, L | 1 |
| Chadha, PS | 1 |
| Zunke, F | 1 |
| Zhu, HL | 1 |
| Davis, AJ | 1 |
| Olesen, SP | 1 |
| Cole, WC | 1 |
| Moffatt, JD | 1 |
| Greenwood, IA | 1 |
| Matsumoto, T | 1 |
| Szasz, T | 1 |
| Tostes, RC | 1 |
| Webb, RC | 2 |
| Dias-Peixoto, MF | 1 |
| Ferreira, AJ | 1 |
| Almeida, PW | 1 |
| Braga, VB | 1 |
| Coutinho, DC | 1 |
| Melo, DS | 1 |
| Gomes Filho, A | 1 |
| Melo, MB | 1 |
| Greco, L | 1 |
| Campagnole-Santos, MJ | 1 |
| Lima, RF | 1 |
| Santos, RA | 1 |
| Guatimosim, S | 1 |
| von Lueder, TG | 1 |
| Gravning, J | 1 |
| How, OJ | 1 |
| Vinge, LE | 1 |
| Ahmed, MS | 1 |
| Krobert, KA | 1 |
| Levy, FO | 1 |
| Larsen, TS | 1 |
| Smiseth, OA | 1 |
| Aasum, E | 1 |
| Attramadal, H | 1 |
| Doggrell, SA | 7 |
| Dimarino, M | 1 |
| Banwait, K | 1 |
| Rattan, S | 1 |
| Cohen, S | 1 |
| DiMarino, AJ | 1 |
| Shimizu, E | 1 |
| Ohyanagi, M | 2 |
| Masutani, M | 1 |
| Iwasaki, T | 2 |
| von Kanel, R | 1 |
| Dimsdale, JE | 7 |
| Adler, KA | 1 |
| Dillon, E | 1 |
| Perez, CJ | 1 |
| Mills, PJ | 6 |
| Girouard, H | 2 |
| Chulak, C | 1 |
| LeJossec, M | 1 |
| Lamontagne, D | 2 |
| de Champlain, J | 4 |
| Veliotes, D | 1 |
| Maseko, M | 2 |
| Tsotetsi, OJ | 1 |
| Naidoo, A | 1 |
| Miyamura, N | 1 |
| Taguchi, T | 1 |
| Murata, Y | 1 |
| Taketa, K | 1 |
| Iwashita, S | 1 |
| Matsumoto, K | 1 |
| Nishikawa, T | 2 |
| Toyonaga, T | 1 |
| Sakakida, M | 1 |
| Araki, E | 1 |
| Brooks, WW | 2 |
| Conrad, CH | 2 |
| Nedder, AP | 1 |
| Bing, OH | 2 |
| Slawsky, MT | 1 |
| HOHNLOSER, E | 1 |
| LEE, TD | 1 |
| ROVETI, GC | 1 |
| ROSS, RS | 1 |
| BAUM, T | 2 |
| HALMAGYI, DF | 1 |
| STARZECKI, B | 1 |
| MCRAE, J | 1 |
| HORNER, GJ | 1 |
| PIPITONE, V | 1 |
| RUSSO, R | 1 |
| CARROZZO, M | 1 |
| DEVANNA, F | 1 |
| DESTASIO, G | 1 |
| COLE, DS | 1 |
| YARROW, S | 1 |
| GADBOYS, HL | 1 |
| WISOFF, G | 1 |
| LITWAK, RS | 1 |
| KALAS, JP | 1 |
| JACOBSON, ED | 1 |
| KLEPPING, J | 1 |
| TRON-LOISEL, H | 1 |
| DIDIER, JP | 1 |
| ESCOUSSE, A | 1 |
| FRANC, B | 1 |
| KRASNOW, N | 1 |
| ROLETT, EL | 1 |
| YURCHAK, PM | 1 |
| HOOD, WB | 1 |
| GORLIN, R | 2 |
| Chen, YY | 2 |
| Vita, JA | 1 |
| Höcht, C | 1 |
| Opezzo, JA | 1 |
| Taira, CA | 1 |
| Rhee, MY | 1 |
| Kwon, NY | 1 |
| Kim, JD | 1 |
| Song, SH | 1 |
| Yoon, YW | 1 |
| Lee, MY | 1 |
| Kim, YK | 1 |
| Lemogoum, D | 1 |
| Flores, G | 1 |
| Van den Abeele, W | 1 |
| Ciarka, A | 1 |
| Leeman, M | 1 |
| Degaute, JP | 1 |
| van de Borne, P | 1 |
| Van Bortel, L | 1 |
| Sorriento, D | 1 |
| Cerullo, V | 1 |
| Iovino, GL | 1 |
| Paudice, A | 1 |
| Elia, A | 1 |
| Arcucci, O | 1 |
| Pastore, L | 1 |
| Salvatore, F | 1 |
| Condorelli, G | 1 |
| Schlaich, MP | 1 |
| Ahlers, BA | 1 |
| Parnell, MM | 1 |
| Kaye, DM | 1 |
| Valentini, M | 1 |
| Julius, S | 7 |
| Palatini, P | 1 |
| Brook, RD | 1 |
| Bard, RL | 1 |
| Bisognano, JD | 1 |
| Kaciroti, N | 1 |
| Delva, P | 1 |
| Pastori, C | 1 |
| Degan, M | 1 |
| Montesi, G | 1 |
| Lechi, A | 1 |
| Anamourlis, C | 1 |
| Gibbs, M | 1 |
| Osadchii, O | 3 |
| Deftereos, DA | 1 |
| Gray, D | 1 |
| MacDonnell, SM | 2 |
| Kubo, H | 2 |
| Crabbe, DL | 1 |
| Renna, BF | 1 |
| Reger, PO | 1 |
| Mohara, J | 1 |
| Smithwick, LA | 1 |
| Koch, WJ | 2 |
| Houser, SR | 2 |
| Libonati, JR | 2 |
| Benter, IF | 2 |
| Francis, I | 2 |
| Khan, I | 1 |
| Cojocel, C | 2 |
| Juggi, JS | 2 |
| Yousif, MH | 2 |
| Canatan, H | 2 |
| Alshawaf, EH | 1 |
| Akhtar, S | 1 |
| Gros, R | 3 |
| Ding, Q | 1 |
| Chorazyczewski, J | 3 |
| Andrews, J | 1 |
| Pickering, JG | 1 |
| Hegele, RA | 1 |
| Feldman, RD | 6 |
| Lappas, G | 1 |
| Daou, GB | 1 |
| Anand-Srivastava, MB | 3 |
| Sun, Y | 1 |
| Carretero, OA | 1 |
| Xu, J | 1 |
| Rhaleb, NE | 1 |
| Wang, F | 1 |
| Lin, C | 1 |
| Yang, JJ | 1 |
| Pagano, PJ | 1 |
| Yang, XP | 1 |
| Schwenke, DO | 1 |
| Pearson, JT | 1 |
| Mori, H | 1 |
| Shirai, M | 1 |
| Kubota, Y | 1 |
| Tanaka, N | 1 |
| Kagota, S | 1 |
| Nakamura, K | 1 |
| Kunitomo, M | 1 |
| Umegaki, K | 1 |
| Shinozuka, K | 1 |
| Frazier, EP | 1 |
| Schneider, T | 1 |
| Michel, MC | 1 |
| Minami, N | 1 |
| Mori, N | 1 |
| Nagasaka, M | 1 |
| Ito, O | 1 |
| Kurosawa, H | 1 |
| Kanazawa, M | 1 |
| Kaku, K | 1 |
| Lee, E | 1 |
| Kohzuki, M | 1 |
| Fernández, N | 2 |
| Monge, L | 2 |
| García-Villalón, AL | 2 |
| Diéguez, G | 2 |
| Kolwicz, SC | 1 |
| Sakamoto, T | 1 |
| Yoshioka, T | 1 |
| Shirakawa, Y | 1 |
| Kamei, T | 1 |
| Murata, A | 1 |
| Asari, Y | 1 |
| Okumura, T | 1 |
| Endo, Y | 1 |
| Shimazu, T | 1 |
| Tomioka, J | 1 |
| Lukhanina, OP | 1 |
| Pil'kevych, NO | 1 |
| Sharabi, Y | 1 |
| Goldstein, DS | 3 |
| Bentho, O | 1 |
| Saleem, A | 1 |
| Pechnik, S | 1 |
| Geraci, MF | 1 |
| Holmes, C | 1 |
| Pacak, K | 1 |
| Eisenhofer, G | 2 |
| Thomas, DP | 1 |
| Xiao, H | 1 |
| Li, ZP | 1 |
| Lesniewski, LA | 1 |
| Donato, AJ | 1 |
| Behnke, BJ | 1 |
| Woodman, CR | 1 |
| Laughlin, MH | 2 |
| Ray, CA | 1 |
| Delp, MD | 1 |
| Saha, S | 1 |
| Li, Y | 1 |
| Kernohan, RJ | 1 |
| Mochizuki, M | 1 |
| Ogawa, K | 1 |
| Kubo, T | 1 |
| Kuwahara, M | 1 |
| Misu, Y | 1 |
| Brodde, OE | 3 |
| Daul, A | 1 |
| O'Hara, N | 2 |
| Bock, KD | 2 |
| Dadkar, NK | 1 |
| Aroskar, VA | 1 |
| Dohadwalla, AN | 1 |
| Baldwin, JJ | 1 |
| Engelhardt, EL | 1 |
| Hirschmann, R | 1 |
| Ponticello, GS | 1 |
| Atkinson, JG | 1 |
| Wasson, BK | 1 |
| Sweet, CS | 1 |
| Scriabine, A | 1 |
| Dahlöf, C | 1 |
| Ljung, B | 1 |
| Ablad, B | 1 |
| Nami, R | 1 |
| Pizzuti, M | 1 |
| Nardi, PL | 1 |
| D'Ascenzo, G | 1 |
| Maioli, E | 1 |
| Gennari, C | 1 |
| Altura, BM | 1 |
| Altura, BT | 1 |
| Kawasaki, H | 2 |
| Cline, WH | 2 |
| Su, C | 2 |
| Semplicini, A | 1 |
| Pessina, AC | 1 |
| Rossi, GP | 1 |
| Hlede, M | 1 |
| Morandin, F | 1 |
| Matsunaga, K | 1 |
| Ueda, M | 1 |
| Yamada, S | 2 |
| Ishima, T | 1 |
| Tomita, T | 2 |
| Hayashi, M | 1 |
| Okada, T | 1 |
| Hayashi, E | 1 |
| Leenen, FH | 5 |
| Boer, P | 2 |
| Dorhout Mees, EJ | 2 |
| Ziegler, MG | 4 |
| Woodson, LC | 2 |
| Torma, Z | 1 |
| Grubic, V | 1 |
| Unyi, G | 1 |
| Morganti, A | 1 |
| Sala, C | 1 |
| Palermo, A | 1 |
| Turolo, L | 1 |
| Zanchetti, A | 2 |
| Laragh, J | 1 |
| Takekoshi, N | 1 |
| Murakami, E | 1 |
| Matsui, S | 1 |
| Murakami, H | 1 |
| Emoto, J | 1 |
| Hashimoto, A | 1 |
| Perin, A | 1 |
| Sessa, A | 1 |
| Desiderio, MA | 1 |
| Tarazi, RC | 7 |
| Iida, K | 6 |
| Sugishita, Y | 6 |
| Matsuda, M | 1 |
| Yamaguchi, T | 1 |
| Ajisaka, R | 2 |
| Matsumoto, R | 1 |
| Fujita, T | 2 |
| Ito, I | 4 |
| Coquil, JF | 1 |
| Hamet, P | 4 |
| Bühler, FR | 3 |
| Kiowski, W | 2 |
| van Brummelen, P | 2 |
| Amann, FW | 2 |
| Bertel, O | 2 |
| Landmann, R | 2 |
| Lütold, BE | 1 |
| Bolli, P | 1 |
| Bhalla, RC | 4 |
| Sharma, RV | 3 |
| Ramanathan, S | 3 |
| Liberatore, C | 1 |
| Platania, A | 1 |
| Reda, G | 1 |
| Lauro, R | 1 |
| Cervoni, P | 2 |
| Herzlinger, H | 1 |
| Lai, FM | 2 |
| Tanikella, T | 2 |
| Jennings, G | 1 |
| Bobik, A | 1 |
| Esler, M | 2 |
| Korner, P | 1 |
| Rangno, RE | 2 |
| Nattel, S | 1 |
| Lutterodt, A | 1 |
| Hoffman, BB | 1 |
| Lefkowitz, RJ | 1 |
| Frieswick, GM | 1 |
| Shideman, FE | 1 |
| Asano, M | 2 |
| Aoki, K | 3 |
| Matsuda, T | 3 |
| Prikryl, P | 4 |
| Rysánek, K | 4 |
| Kunovská, V | 3 |
| Bílková, B | 1 |
| Továrek, J | 2 |
| Cechovský, K | 2 |
| Kudo, Y | 1 |
| Sokabe, H | 1 |
| Ito, H | 1 |
| Tonai, N | 1 |
| Hirakawa, S | 1 |
| Schoeffter, P | 1 |
| Volpe, M | 6 |
| Ricciardelli, B | 6 |
| Sacca, L | 1 |
| Ungaro, B | 1 |
| Rengo, F | 4 |
| Condorelli, M | 6 |
| Rechtoríková, O | 1 |
| Piekarska, T | 1 |
| Günther, T | 1 |
| Vormann, J | 1 |
| Förster, R | 1 |
| Limbird, LE | 1 |
| Nadeau, J | 1 |
| Robertson, D | 2 |
| Wood, AJ | 4 |
| Borkowski, KR | 2 |
| Porter, M | 1 |
| Mele, A | 1 |
| Cuocolo, A | 5 |
| De Luca, N | 3 |
| Luca, C | 1 |
| Marchini, F | 1 |
| Usardi, MM | 1 |
| Picotti, GB | 1 |
| Veniero, AM | 4 |
| De Simone, A | 1 |
| Burnier, M | 2 |
| Brunner, HR | 3 |
| Brunner, DB | 1 |
| Hagen, EC | 1 |
| Toal, CB | 1 |
| Soltis, EE | 5 |
| Field, FP | 3 |
| Vasquez, EC | 2 |
| Cabral, AM | 1 |
| Bianchetti, MG | 1 |
| Beretta-Piccoli, C | 4 |
| Weidmann, P | 7 |
| Ferrier, C | 4 |
| Link, L | 1 |
| Gerber, A | 1 |
| Horwitz, D | 1 |
| Keiser, HR | 2 |
| Polinsky, RJ | 1 |
| Kopin, IJ | 2 |
| Viano, DC | 1 |
| Todorov, S | 1 |
| Petkov, O | 1 |
| Bruschi, G | 1 |
| Bruschi, ME | 1 |
| Caroppo, M | 1 |
| Orlandini, G | 1 |
| Pavarani, C | 1 |
| Cavatorta, A | 1 |
| Chiariello, M | 2 |
| Ventriglia, G | 2 |
| Weinstock, M | 2 |
| McCarty, R | 2 |
| Zmbova, B | 1 |
| Stojanova, D | 2 |
| Stakic, D | 1 |
| Tadzer, I | 1 |
| Bogdanova, V | 1 |
| Wexler, BC | 4 |
| McMurtry, JP | 1 |
| Elola, J | 1 |
| Medina, A | 1 |
| Macaya, C | 1 |
| Bethencourt, A | 1 |
| Thibault, L | 1 |
| Chan, PS | 1 |
| Kotchen, TA | 2 |
| Guthrie, GP | 4 |
| McKean, H | 1 |
| Kotchen, JM | 1 |
| Ellis, ME | 1 |
| Sahay, JN | 1 |
| Chatterjee, SS | 1 |
| Cruickshank, JM | 1 |
| Ellis, SH | 1 |
| Smith, RS | 1 |
| Reid, JL | 2 |
| Warren, DJ | 1 |
| Brown, MJ | 1 |
| Lhoste, FJ | 1 |
| Zamboulis, C | 1 |
| Ind, PW | 1 |
| Jenner, DA | 1 |
| Dollery, CT | 2 |
| Langlois, S | 1 |
| Henquet, JW | 1 |
| van Baak, M | 1 |
| Schols, M | 1 |
| Rahn, KH | 3 |
| Higuchi, Y | 1 |
| Tuttle, R | 1 |
| Elias, B | 1 |
| McCleary, M | 1 |
| Endy, T | 1 |
| Kawano, Y | 1 |
| Fukiyama, K | 1 |
| Takeya, Y | 1 |
| Abe, I | 2 |
| Omae, T | 1 |
| Krieger, EM | 1 |
| Chatelain, P | 2 |
| Robberecht, P | 2 |
| De Neef, P | 2 |
| Camus, JC | 1 |
| Heuse, D | 1 |
| Christophe, J | 2 |
| Chiu, TH | 1 |
| Katovich, MJ | 3 |
| Barney, CC | 2 |
| Fregly, MJ | 4 |
| Yeager, JC | 1 |
| Iams, SG | 2 |
| Hultgren, HN | 1 |
| Shettigar, UR | 1 |
| Bogoslovova, T | 3 |
| Staneva, D | 1 |
| Saxena, PR | 1 |
| van Boom, M | 1 |
| van Doorn, K | 1 |
| Cairo-Rawlins, WI | 1 |
| Moreno, NN | 1 |
| de Campo, T | 1 |
| Kaiser, GA | 1 |
| Pallares, VS | 1 |
| Reznikova, MB | 1 |
| Postnov, IuV | 1 |
| Chu, D | 1 |
| Cocco, G | 1 |
| Schweda, E | 1 |
| Haeusler, G | 1 |
| Strozzi, C | 1 |
| Saragoca, MA | 1 |
| Blankesteijn, WM | 1 |
| Willems, PH | 1 |
| Graafsma, SJ | 1 |
| de Pont, JJ | 1 |
| Thien, T | 1 |
| Rupp, H | 1 |
| Dhalla, KS | 1 |
| Dhalla, NS | 1 |
| Rubino, A | 1 |
| Burnstock, G | 1 |
| Zhang, XQ | 1 |
| Moore, RL | 1 |
| Tenhave, T | 1 |
| Cheung, JY | 1 |
| Krasnikova, LT | 1 |
| Vikhert, OA | 1 |
| Mazaev, AV | 1 |
| Tan, CM | 1 |
| Guimarães, S | 1 |
| Albino-Teixeira, A | 1 |
| Paiva, MQ | 1 |
| Atkins, FL | 1 |
| DiMauro, PG | 1 |
| Robinson, KG | 1 |
| Stein, CM | 2 |
| Nelson, R | 2 |
| Deegan, R | 2 |
| He, H | 1 |
| Wood, M | 2 |
| García, JL | 1 |
| Gomez, B | 1 |
| Watkins, LL | 1 |
| Bogoyevitch, MA | 1 |
| Fuller, SJ | 1 |
| Sugden, PH | 1 |
| Taddei, S | 3 |
| Virdis, A | 1 |
| Mattei, P | 1 |
| Favilla, S | 2 |
| Salvetti, A | 3 |
| de Novellis, V | 1 |
| Filippelli, A | 1 |
| Loffreda, A | 1 |
| Rossi, F | 1 |
| Coy, TV | 1 |
| Ancoli-Israel, S | 2 |
| Clausen, JL | 1 |
| Nelesen, RA | 1 |
| Lang, CC | 1 |
| Brown, RM | 1 |
| He, HB | 1 |
| Tawfik-Schlieper, H | 1 |
| Moll, M | 1 |
| Schmid, B | 1 |
| Schwinger, RH | 1 |
| Paul, M | 1 |
| Ganten, D | 1 |
| Böhm, M | 4 |
| Inoko, M | 1 |
| Kihara, Y | 1 |
| Morii, I | 1 |
| Fujiwara, H | 1 |
| Sasayama, S | 1 |
| De Caprio, L | 1 |
| Di Palma, A | 1 |
| De Rosa, ML | 1 |
| Lirato, C | 1 |
| Canonico, V | 1 |
| Giordano, A | 1 |
| Scognamiglio, P | 1 |
| Surman, AJ | 2 |
| Zavecz, JH | 1 |
| Battarbee, HD | 1 |
| O'Donnell, JM | 1 |
| Middeke, M | 1 |
| Reder, S | 1 |
| Holzgreve, H | 1 |
| Mäkynen, H | 1 |
| Arvola, P | 1 |
| Vapaatalo, H | 1 |
| Pörsti, I | 4 |
| Barbieri, M | 2 |
| Varani, K | 1 |
| Cerbai, E | 3 |
| Guerra, L | 1 |
| Li, Q | 1 |
| Borea, PA | 1 |
| Mugelli, A | 3 |
| Yoshikawa, H | 1 |
| Fukuda, K | 1 |
| Wanaka, Y | 1 |
| Kasamatsu, K | 1 |
| Baba, A | 1 |
| Nishio, I | 1 |
| Masuyama, Y | 1 |
| Wolfel, EE | 1 |
| Selland, MA | 1 |
| Mazzeo, RS | 1 |
| Reeves, JT | 1 |
| Arribas, S | 1 |
| Marín, J | 2 |
| Ponte, A | 1 |
| Balfagón, G | 2 |
| Radó, J | 1 |
| Arányi, J | 1 |
| Deák, G | 1 |
| Rétai, G | 1 |
| Cockcroft, JR | 1 |
| Chowienczyk, PJ | 1 |
| Benjamin, N | 1 |
| Ritter, JM | 1 |
| Harmsen, E | 1 |
| Schoemaker, R | 1 |
| Ruzicka, M | 1 |
| Fujieda, K | 2 |
| Yukisada, K | 5 |
| Saito, T | 2 |
| Kai, N | 2 |
| Yamamoto, K | 3 |
| Iwata, J | 2 |
| Deguchi, F | 1 |
| Inagaki, Y | 2 |
| Clark, CJ | 1 |
| Milligan, G | 1 |
| Connell, JM | 1 |
| Yi, G | 2 |
| Stone, S | 1 |
| Dao, B | 1 |
| McConnaughey, MM | 1 |
| Sahai, A | 1 |
| Ganguly, PK | 1 |
| Moravec, CS | 2 |
| Keller, E | 1 |
| Bond, M | 2 |
| Ito, M | 1 |
| Soma, M | 2 |
| Izumi, Y | 2 |
| Kanmatsuse, K | 1 |
| Delbridge, LM | 1 |
| Connell, PJ | 1 |
| Morgan, TO | 1 |
| Harris, PJ | 1 |
| Fuchs, LC | 1 |
| Nuno, D | 1 |
| Lamping, KG | 1 |
| Johnson, AK | 1 |
| Wu, L | 1 |
| Serio, M | 1 |
| Potenza, MA | 1 |
| Montagnani, M | 1 |
| Mansi, G | 1 |
| Mitolo-Chieppa, D | 1 |
| Jirillo, E | 1 |
| Vyas, SJ | 2 |
| Ogiku, N | 1 |
| Ishida, R | 1 |
| Saeki, K | 1 |
| Sugiura, M | 1 |
| Bertolino, S | 1 |
| Julien, C | 2 |
| Medeiros, IA | 2 |
| Cuisinaud, G | 1 |
| Vincent, M | 3 |
| Barrès, C | 2 |
| de Boer, RE | 1 |
| Steegstra, MR | 1 |
| Kroezen, PA | 1 |
| Smit, J | 1 |
| Zaagsma, J | 1 |
| Hutri-Kähönen, N | 2 |
| Kähönen, M | 3 |
| Tolvanen, JP | 3 |
| Wu, X | 3 |
| Sallinen, K | 2 |
| Holécyová, A | 1 |
| Török, J | 1 |
| Bernátová, I | 1 |
| Pechánová, O | 1 |
| Gómez, AM | 1 |
| Valdivia, HH | 1 |
| Cheng, H | 1 |
| Lederer, MR | 1 |
| Santana, LF | 1 |
| Cannell, MB | 1 |
| McCune, SA | 2 |
| Altschuld, RA | 2 |
| Lederer, WJ | 1 |
| Legssyer, AK | 1 |
| Hove-Madsen, L | 1 |
| Hoerter, J | 1 |
| Fischmeister, R | 1 |
| Mistry, DN | 1 |
| Henderson, CJ | 1 |
| Lin, JC | 1 |
| Liu, DM | 1 |
| Wang, Y | 1 |
| McConnell, BK | 1 |
| Morano, I | 1 |
| VanNess, JM | 1 |
| Casto, RM | 1 |
| Overton, JM | 1 |
| Chang, HR | 1 |
| Chen, SS | 1 |
| Tsao, DA | 1 |
| Cheng, JT | 1 |
| Ho, CK | 1 |
| Yu, HS | 1 |
| Yu, XC | 1 |
| Wang, HX | 1 |
| Wong, TM | 1 |
| Cardillo, C | 1 |
| Kilcoyne, CM | 1 |
| Quyyumi, AA | 1 |
| Cannon, RO | 1 |
| Panza, JA | 1 |
| Petcu, EB | 1 |
| Barnett, CW | 1 |
| Suarez, EC | 1 |
| Sumida, E | 2 |
| Nohara, M | 1 |
| Muro, A | 1 |
| Kaku, H | 1 |
| Koga, Y | 1 |
| Toshima, H | 1 |
| Imaizumi, T | 1 |
| Tanaka, M | 1 |
| Kotchi Kotchi, E | 1 |
| Weisselberg, T | 1 |
| Röhnert, P | 1 |
| Preiss, M | 1 |
| Heinroth-Hoffmann, I | 2 |
| Osten, B | 1 |
| White, M | 1 |
| Fourney, A | 1 |
| Bartunek, J | 1 |
| Dempsey, S | 1 |
| Weinberg, EO | 1 |
| Ito, N | 1 |
| Tajima, M | 1 |
| Rohrbach, S | 1 |
| Lorell, BH | 1 |
| Clemow, DB | 1 |
| Steers, WD | 1 |
| Tuttle, JB | 1 |
| Mokkapatti, R | 1 |
| Romero, GG | 1 |
| Inoue, T | 1 |
| Dubey, RK | 1 |
| Stout, AK | 1 |
| Marcil, J | 1 |
| Anderson, KM | 1 |
| Eckhart, AD | 1 |
| Willette, RN | 1 |
| Inagaki, M | 1 |
| Yokota, M | 1 |
| Izawa, H | 1 |
| Ishiki, R | 1 |
| Nagata, K | 1 |
| Iwase, M | 1 |
| Yamada, Y | 1 |
| Koide, M | 2 |
| Sobue, T | 1 |
| Vajo, Z | 1 |
| Cruz, E | 1 |
| Szekacs, B | 1 |
| Dachman, W | 1 |
| Yu, BH | 2 |
| Sanae, F | 1 |
| Hayashi, H | 2 |
| Chisaki, K | 1 |
| Komatsu, Y | 1 |
| Chruscinski, AJ | 1 |
| Rohrer, DK | 1 |
| Schauble, E | 1 |
| Desai, KH | 1 |
| Bernstein, D | 1 |
| Kobilka, BK | 1 |
| Pino, R | 1 |
| Rodriguez, ML | 1 |
| Manso, AM | 1 |
| Encabo, A | 1 |
| Ferrer, M | 1 |
| Kalliovalkama, J | 1 |
| Jolma, P | 1 |
| Holm, P | 1 |
| Meek, MD | 1 |
| Benovic, JL | 1 |
| Ferguson, SS | 1 |
| Calls, J | 1 |
| Cases, A | 1 |
| Lario, S | 1 |
| Esforzado, N | 1 |
| Paré, JC | 1 |
| Azqueta, M | 1 |
| Jimenez, W | 1 |
| Rivera-Fillat, F | 1 |
| Wright, CE | 1 |
| Hawkes, AL | 1 |
| Angus, JA | 2 |
| Candy, G | 1 |
| Samani, N | 1 |
| Norton, G | 1 |
| Woodiwiss, A | 1 |
| Radevski, I | 1 |
| Wheatley, A | 1 |
| Cockcroft, J | 1 |
| Hall, IP | 1 |
| Moriguchi, A | 1 |
| Nakagami, H | 1 |
| Kotani, N | 1 |
| Higaki, J | 1 |
| Ogihara, T | 1 |
| Shimamura, K | 1 |
| Sekiguchi, F | 1 |
| Sunano, S | 1 |
| Zhou, MS | 1 |
| Kosaka, H | 1 |
| Yoneyama, H | 1 |
| Bohlender, J | 2 |
| Hildenbrand, U | 2 |
| Schlegel, WP | 2 |
| Hempel, P | 2 |
| Nissen, E | 1 |
| Krause, EG | 2 |
| Bartel, S | 2 |
| Evans, SJ | 1 |
| Dalton, GR | 1 |
| Levi, AJ | 1 |
| Schmidt, ND | 1 |
| Goto, K | 1 |
| Fujii, K | 1 |
| Clausen, J | 1 |
| Loredo, JS | 1 |
| Doursout, MF | 1 |
| Wouters, P | 1 |
| Kashimoto, S | 1 |
| Hartley, CJ | 1 |
| Rabinovitz, R | 1 |
| Chelly, JE | 1 |
| Vázquez-Pérez, S | 1 |
| Navarro-Cid, J | 1 |
| de las Heras, N | 1 |
| Cediel, E | 1 |
| Sanz-Rosa, D | 1 |
| Ruilope, LM | 1 |
| Cachofeiro, V | 1 |
| Lahera, V | 1 |
| Cabassi, A | 1 |
| Dumont, EC | 1 |
| Bouchard, JF | 1 |
| Le Jossec, M | 1 |
| Besner, JG | 1 |
| Wagner, KD | 1 |
| Günther, J | 1 |
| Luft, FC | 2 |
| Bokník, P | 1 |
| Kirchhefer, U | 1 |
| Knapp, J | 1 |
| Linck, B | 1 |
| Lüss, H | 1 |
| Müller, T | 1 |
| Schmitz, W | 2 |
| Brodde, O | 1 |
| Neumann, J | 1 |
| Farag, NH | 1 |
| Perez, C | 1 |
| Zhang, W | 1 |
| Dumitrescu, C | 1 |
| Narayan, P | 1 |
| Efimov, IR | 1 |
| Cheng, Y | 1 |
| Radin, MJ | 1 |
| Jordan, J | 1 |
| Tank, J | 1 |
| Shannon, JR | 1 |
| Diedrich, A | 1 |
| Lipp, A | 1 |
| Schröder, C | 1 |
| Arnold, G | 1 |
| Sharma, AM | 1 |
| Biaggioni, I | 1 |
| von Bahr, C | 1 |
| Collste, P | 2 |
| Frisk-Holmberg, M | 2 |
| Haglund, K | 2 |
| Jorfelt, L | 1 |
| Orme, M | 1 |
| Ostman, J | 2 |
| Sjoqvist, F | 1 |
| Brittain, RT | 1 |
| Levy, GP | 3 |
| Mehta, J | 1 |
| Cohn, JN | 1 |
| Ahlquist, RP | 1 |
| Woods, JR | 1 |
| Dandavino, A | 1 |
| Murayama, K | 1 |
| Brinkman, CR | 1 |
| Assali, NS | 1 |
| Kuchel, O | 3 |
| Buu, NT | 1 |
| Cuche, JL | 1 |
| Boucher, R | 1 |
| Genest, J | 3 |
| Linée, P | 2 |
| Le Pollès, JB | 2 |
| Lacroix, P | 2 |
| Pape, D | 2 |
| Quiniou, P | 1 |
| Van den Driessche, J | 2 |
| Simon, G | 1 |
| Andersson, O | 1 |
| Lubbe, WF | 1 |
| Zisel'man, SB | 1 |
| Sivkov, SI | 1 |
| Drew, GM | 1 |
| Hilditch, A | 1 |
| Sanders, GL | 1 |
| Murray, A | 1 |
| Rawlins, MD | 2 |
| Taylor, EM | 1 |
| Roe, AM | 1 |
| Slater, RA | 1 |
| Derkx, FH | 1 |
| von Gool, JM | 1 |
| Wenting, GJ | 1 |
| Verhoeven, RP | 1 |
| Man in 't Veld, AJ | 2 |
| Schalekamp, MA | 3 |
| Cohen, ML | 1 |
| Wiley, KS | 1 |
| Quinones, MA | 1 |
| Gaasch, WH | 1 |
| Cole, JS | 1 |
| Alexander, JK | 1 |
| Huxtable, R | 1 |
| Chubb, J | 1 |
| Bressler, R | 1 |
| Hollander, W | 1 |
| Prusty, S | 1 |
| Kirkpatrick, B | 1 |
| Paddock, J | 1 |
| Nagraj, S | 1 |
| Dejalle, J | 1 |
| Cession-Fossion, A | 1 |
| Lecomte, J | 1 |
| Triner, L | 1 |
| Vulliemoz, Y | 1 |
| Verosky, M | 1 |
| Manger, WM | 1 |
| Shibata, S | 3 |
| Tasaki, TK | 1 |
| Ichord, RN | 1 |
| Messerli, FH | 1 |
| Tolis, G | 1 |
| Fraysse, J | 1 |
| Nowaczynski, W | 1 |
| Staneva-Stoycheva, D | 1 |
| Kiowski, DW | 1 |
| Limas, CJ | 2 |
| Limas, C | 2 |
| Montastruc, P | 2 |
| Montastruc, JL | 1 |
| Frölich, JC | 1 |
| Hollifield, JW | 1 |
| Michelakis, AM | 1 |
| Vesper, BS | 1 |
| Wilson, JP | 1 |
| Shand, DG | 2 |
| Seyberth, HJ | 1 |
| Frölich, WH | 1 |
| Oates, JA | 1 |
| McAllister, RG | 1 |
| Love, DW | 1 |
| Dominic, JA | 1 |
| Scoggins, BA | 1 |
| Allen, KJ | 1 |
| Coghlan, JP | 1 |
| Denton, DA | 1 |
| Graham, WF | 1 |
| Humphery, TJ | 1 |
| Whitworth, JA | 1 |
| Meekers, J | 1 |
| Missotten, A | 1 |
| Fagard, R | 1 |
| Demuynck, D | 1 |
| Harvengt, C | 1 |
| Pas, P | 1 |
| Billiet, L | 1 |
| Amery, A | 2 |
| Charlier, R | 1 |
| Bauthier, J | 1 |
| Richard, J | 1 |
| Clement, DL | 1 |
| Palmer, GC | 1 |
| Claeys, M | 1 |
| Takata, Y | 1 |
| Sinaiko, AR | 1 |
| Mirkin, BL | 1 |
| Zweifler, A | 1 |
| Randall, O | 1 |
| DeQuattro, V | 1 |
| Ashley, AT | 1 |
| Deragon, G | 1 |
| Regoli, D | 1 |
| Rioux, F | 2 |
| Ashley, T | 1 |
| Walsh, GM | 1 |
| Baricos, WH | 1 |
| MacPhee, AA | 1 |
| Kuriyama, H | 1 |
| Suzuki, H | 1 |
| Godfraind, T | 1 |
| Dieu, D | 1 |
| Weiss, L | 2 |
| Lundgren, Y | 2 |
| De Plaen, JF | 1 |
| Reybrouck, T | 1 |
| Barrillon, A | 1 |
| Grand, A | 1 |
| Esler, MD | 3 |
| Randall, OS | 2 |
| Berkowitz, BA | 1 |
| Kikawada, R | 2 |
| Noro, C | 2 |
| Mateos, DA | 1 |
| Tsuzuki, S | 1 |
| Nakiri, K | 1 |
| Bittencourt, D | 1 |
| Zerbini, EJ | 1 |
| Orme, ML | 1 |
| Ilebekk, A | 1 |
| Thorvaldson, J | 1 |
| Kiil, F | 2 |
| Staneva-Stoytcheva, D | 1 |
| Illnerová, H | 1 |
| Ablrecht, I | 1 |
| Chalmers, JP | 1 |
| Hutchins, PM | 1 |
| Green, AW | 1 |
| Rains, TD | 1 |
| Ibrahim, MM | 1 |
| Dustan, HP | 5 |
| Bravo, EL | 1 |
| Gifford, RW | 1 |
| Segal, MS | 1 |
| Ishikawa, S | 1 |
| Kashima, T | 1 |
| Ellis, C | 1 |
| Bennett, J | 1 |
| Denef, B | 1 |
| Popeye, R | 1 |
| Geest, HD | 1 |
| Kesteloot, H | 1 |
| Gudeska, S | 1 |
| Glavas, E | 1 |
| Nikodijević, B | 1 |
| Tsuyusaki, T | 1 |
| Muramatsu, J | 1 |
| Kakubari, Y | 1 |
| London, GM | 2 |
| Safar, ME | 2 |
| Weiss, YA | 2 |
| Milliez, PL | 2 |
| Nishimura, Y | 1 |
| Usui, H | 1 |
| Suzuki, A | 2 |
| Kajimoto, N | 1 |
| Yamanishi, Y | 1 |
| Das, AM | 1 |
| Harris, DA | 1 |
| Gill, J | 1 |
| Fonseca, V | 1 |
| Dandona, P | 1 |
| Jeremy, JY | 1 |
| Ohsuzu, F | 1 |
| Katsushika, S | 1 |
| Maie, S | 1 |
| Akanuma, M | 1 |
| Yanagida, S | 1 |
| Sakata, N | 1 |
| Ishida, H | 1 |
| Aosaki, N | 1 |
| Nakamura, H | 1 |
| Suzuki, Y | 3 |
| Kuwajima, I | 2 |
| Kanemaru, A | 2 |
| Shimosawa, T | 1 |
| Hoshino, S | 2 |
| Sakai, M | 1 |
| Matsushita, S | 2 |
| Ueda, K | 1 |
| Kuramoto, K | 2 |
| Krasnikova, T | 1 |
| Minchuna, V | 1 |
| Runikhin, A | 1 |
| Arabidze, G | 1 |
| Mazaev, A | 1 |
| Yurenev, AP | 1 |
| Parfyonova, EV | 1 |
| Krasnikova, TL | 1 |
| Aripova, NA | 1 |
| Porter, JP | 1 |
| Carmignani, M | 1 |
| Preziosi, P | 1 |
| Del Carmine, R | 1 |
| Porcelli, G | 1 |
| Volpe, AR | 1 |
| Gierschik, P | 1 |
| Knorr, A | 1 |
| Larisch, K | 1 |
| Weismann, K | 1 |
| Erdmann, E | 2 |
| Schneider, H | 1 |
| Rump, LC | 1 |
| Schuster, MJ | 1 |
| Schollmeyer, P | 1 |
| Stroh, JA | 1 |
| Ward, JE | 1 |
| Coles, P | 1 |
| Cox, H | 1 |
| Dubus, I | 1 |
| Contard, F | 1 |
| Marotte, F | 1 |
| Samuel, JL | 1 |
| Rappaport, L | 1 |
| Benzoni, D | 1 |
| Sassard, J | 2 |
| Saxenhofer, H | 2 |
| Morger, D | 1 |
| Shaw, SG | 1 |
| Ikawa, H | 1 |
| Lo, M | 1 |
| Boomsma, F | 3 |
| Cerutti, C | 1 |
| Leskinen, M | 1 |
| Uhari, M | 1 |
| Tarkka, M | 1 |
| Kettunen, R | 1 |
| Shimozawa, T | 1 |
| Ludwig, J | 1 |
| Halbrügge, T | 1 |
| Graefe, KH | 1 |
| Brandt, CM | 1 |
| Boulenc, JM | 1 |
| Carrière, T | 1 |
| Verdun, A | 1 |
| Imbs, JL | 1 |
| Henrich, WL | 1 |
| Levi, M | 1 |
| Bartsch, W | 1 |
| Sponer, G | 1 |
| Strein, K | 1 |
| Müller-Beckmann, B | 1 |
| Kling, L | 1 |
| Böhm, E | 1 |
| Martin, U | 1 |
| Borbe, HO | 1 |
| Cohen, CA | 1 |
| Od-Allah, SK | 1 |
| Cimini, CM | 1 |
| Weiss, HR | 1 |
| Chou, HT | 1 |
| Yokota, Y | 1 |
| Fukuzaki, H | 1 |
| Neyses, L | 1 |
| Vetter, H | 1 |
| Mills, P | 1 |
| Dimsdale, J | 2 |
| Ziegler, M | 2 |
| Brown, M | 1 |
| Naslund, T | 1 |
| Silberstein, DJ | 1 |
| Merrell, WJ | 1 |
| Nadeau, JH | 1 |
| Buñag, RD | 1 |
| Krizsan, D | 1 |
| Sexton, WL | 1 |
| Korthuis, RJ | 1 |
| Fukuda, N | 1 |
| Honda, M | 2 |
| Minato, M | 1 |
| Hatano, M | 1 |
| Hurwitz, ML | 1 |
| Rosendorff, C | 1 |
| Doshan, HD | 1 |
| Rosenthal, RR | 1 |
| Brown, R | 1 |
| Slutsky, A | 1 |
| Applin, WJ | 1 |
| Caruso, FS | 1 |
| Agabiti-Rosei, E | 3 |
| Muiesan, ML | 3 |
| Romanelli, G | 2 |
| Beschi, M | 2 |
| Castellano, M | 2 |
| Muiesan, G | 3 |
| Morioka, S | 1 |
| Ohoka, M | 1 |
| Yamori, Y | 1 |
| Moriyama, K | 1 |
| Vargas, F | 2 |
| Haro, JM | 2 |
| Garcia-Torres, L | 1 |
| Soler, A | 1 |
| Garcia del Rio, C | 2 |
| Senn, N | 1 |
| Garay, RP | 1 |
| Grammas, P | 1 |
| Dereski, MO | 1 |
| Diglio, C | 1 |
| Giacomelli, F | 1 |
| Wiener, J | 1 |
| Kamibayashi, C | 1 |
| Jazayeri, A | 1 |
| Meyer, WJ | 1 |
| Uehlinger, DE | 2 |
| Ferrier, CP | 1 |
| Matthieu, R | 1 |
| Reuter, K | 1 |
| Gnaedinger, MP | 2 |
| Shaw, S | 1 |
| Draper, AJ | 1 |
| Meghji, S | 1 |
| Redfern, PH | 1 |
| Matsumori, Y | 1 |
| Kawamoto, H | 1 |
| Shibata, R | 1 |
| Giannattasio, C | 1 |
| Cleroux, J | 1 |
| Seravalle, G | 1 |
| Grassi, G | 1 |
| Mancia, G | 1 |
| Yang, Q | 1 |
| Fan, J | 1 |
| van den Meiracker, AH | 1 |
| Man in't Veld, AJ | 1 |
| Fischberg, DJ | 1 |
| Molinoff, PB | 1 |
| Tuan, RS | 1 |
| Papies, B | 1 |
| Schimke, I | 1 |
| Moritz, V | 1 |
| Schohn, D | 2 |
| Gnädinger, MP | 1 |
| Bürgisser, E | 1 |
| Jahn, H | 2 |
| Kikta, DC | 1 |
| Threatte, RM | 1 |
| Torres, JL | 1 |
| Kawamoto, A | 1 |
| Shimada, K | 1 |
| Matsubayashi, K | 1 |
| Chikamori, T | 1 |
| Kuzume, O | 1 |
| Ogura, H | 1 |
| Ozawa, T | 1 |
| Koshibu, Y | 1 |
| Sakaguchi, A | 1 |
| Tonooka, M | 1 |
| Balaraman, R | 1 |
| Gulati, OD | 1 |
| Bhatt, JD | 1 |
| Rathod, SP | 1 |
| Hemavathi, KG | 1 |
| Fujimoto, S | 2 |
| Dohi, Y | 2 |
| Schmid, G | 1 |
| Geiger, H | 1 |
| Bahner, U | 1 |
| Heidland, A | 1 |
| Graham, R | 1 |
| Beuckelmann, D | 1 |
| Diet, F | 1 |
| Feiler, G | 1 |
| Lohse, MJ | 1 |
| Daul, AE | 1 |
| Wang, XL | 1 |
| Dagnino, J | 1 |
| Prys-Roberts, C | 1 |
| Gradin, K | 1 |
| Elam, M | 1 |
| Persson, B | 1 |
| Curzio, J | 1 |
| Vincent, J | 1 |
| Minnear, FL | 1 |
| Johnson, A | 1 |
| Malik, AB | 1 |
| Antonaccio, MJ | 2 |
| High, J | 1 |
| DeForrest, JM | 1 |
| Sybertz, E | 1 |
| Verbeuren, TJ | 1 |
| Herman, AG | 1 |
| Marzán, G | 1 |
| Enero, MA | 1 |
| Vincent, HH | 1 |
| Derkx, F | 1 |
| Yasuda, M | 2 |
| Oku, H | 2 |
| Hirota, K | 1 |
| Kajino, H | 1 |
| Nishikimi, T | 2 |
| Kawarabayashi, T | 1 |
| Murai, K | 2 |
| Yoshimura, T | 1 |
| Takeuchi, K | 2 |
| Takeda, T | 2 |
| Komatsu, H | 1 |
| Silver, PJ | 1 |
| Michalak, RJ | 1 |
| Kocmund, SM | 1 |
| Vondrácek, V | 2 |
| Prásek, J | 2 |
| Schütz, W | 1 |
| Hörtnagl, H | 1 |
| Magometschnigg, D | 1 |
| Mende, U | 1 |
| Scholz, H | 1 |
| Shepherd, RE | 2 |
| Bah, MD | 1 |
| Nelson, KM | 2 |
| Henley, WN | 2 |
| Wilson, KM | 1 |
| Hathaway, S | 1 |
| Spitzer, JA | 1 |
| Murakami, T | 1 |
| Katada, T | 1 |
| Yasuda, H | 1 |
| Städler, P | 1 |
| Leonardi, L | 1 |
| Riesen, W | 1 |
| Ziegler, W | 1 |
| Marone, C | 1 |
| Iloeje, E | 1 |
| Hayashi, S | 1 |
| Wickler, SJ | 1 |
| Gray, S | 1 |
| Horwitz, BA | 1 |
| Casanova, I | 1 |
| Fernández, MA | 1 |
| Lee, TJ | 1 |
| Shirasaki, Y | 1 |
| Nickols, GA | 1 |
| Carvalho, MH | 1 |
| Scivoletto, R | 1 |
| Fortes, ZB | 1 |
| Nigro, D | 1 |
| Cordellini, S | 1 |
| Lockley, OE | 1 |
| van der Voort, J | 1 |
| Sumners, C | 1 |
| Chernow, B | 1 |
| Coyle, J | 1 |
| Cruess, D | 1 |
| Lake, CR | 1 |
| Soltis, TD | 1 |
| Bohr, DF | 1 |
| Dietz, JR | 1 |
| Beck, A | 1 |
| Grasmugg, B | 1 |
| Singer, E | 1 |
| Bacher, S | 1 |
| Raberger, G | 1 |
| Kasser, A | 1 |
| Waeber, B | 1 |
| Nussberger, J | 1 |
| Burris, J | 1 |
| Murphy, VA | 1 |
| Johanson, CE | 1 |
| Valli, VV | 1 |
| Sadasivudu, B | 1 |
| Davy, M | 1 |
| Heimburger, M | 1 |
| Midol-Monnet, M | 1 |
| Beslot, F | 1 |
| Cohen, Y | 1 |
| Zimlichman, R | 1 |
| Stull, R | 1 |
| Folio, J | 1 |
| Levinson, PD | 1 |
| Iriuchijima, J | 1 |
| Duncan, JJ | 1 |
| Farr, JE | 1 |
| Upton, SJ | 1 |
| Hagan, RD | 1 |
| Oglesby, ME | 1 |
| Blair, SN | 1 |
| Magun, JG | 1 |
| Goodwin, JF | 1 |
| Bodem, G | 1 |
| Chidsey, CA | 1 |
| Krikler, D | 1 |
| Folkow, B | 1 |
| Amer, MS | 1 |
| Gomoll, AW | 1 |
| Perhach, JL | 1 |
| Ferguson, HC | 1 |
| McKinney, GR | 1 |
| Raynaud, R | 1 |
| Brochier, M | 1 |
| Néel, JL | 1 |
| Fauchier, JP | 1 |
| Raynaud, P | 1 |
| Hansson, L | 2 |
| Cavaliere, T | 1 |
| Marcano, BA | 1 |
| Moss, AJ | 1 |
| Muscholl, E | 2 |
| Mueller, RA | 1 |
| Axelrod, J | 1 |
| Bartosová, D | 1 |
| Chvapil, M | 1 |
| Korecký, B | 1 |
| Poupa, O | 1 |
| Rakusan, K | 1 |
| Turek, Z | 1 |
| Vízek, M | 1 |
| Cohen, J | 1 |
| Meerson, FZ | 1 |
| Freis, ED | 1 |
| Heath, WC | 1 |
| Luchsinger, PC | 1 |
| Snell, RE | 1 |
| Schmitt, H | 3 |
| Rowles, G | 1 |
| Sapira, JD | 1 |
| Klaniecki, T | 1 |
| Ratkin, G | 1 |
| Largis, EE | 1 |
| Allen, DO | 1 |
| Clark, J | 1 |
| Ashmore, J | 1 |
| Lewis, PJ | 1 |
| George, CF | 1 |
| Prichard, BN | 1 |
| Unger, DL | 2 |
| Unger, L | 2 |
| Lamarche, M | 1 |
| Royer, R | 1 |
| Heisel, J | 1 |
| Deptalla, H | 1 |
| Wiegershausen, B | 1 |
| Baïsset, A | 1 |
| Cotonat, J | 1 |
| Lydtin, H | 1 |
| Frohlich, ED | 6 |
| Loggie, JM | 1 |
| Van Maanen, EF | 1 |
| von Egidy, H | 1 |
| Simpson, LL | 1 |
| Blumstein, CG | 1 |
| Zweifler, AJ | 1 |
| Matsuura, T | 1 |
| Goodyer, AV | 1 |
| Bugge-Asperheim, B | 1 |
| Skivolocki, WP | 1 |
| Thomford, NR | 1 |
| Schott, GD | 1 |
| McArdle, B | 1 |
| Pfeffer, MA | 1 |
| Pfeffer, JM | 1 |
| Beaufils, F | 1 |
| Bousser, P | 1 |
| Chapman, A | 1 |
| McClish, A | 1 |
| Bénazéra, A | 1 |
| Lapointe, P | 1 |
| Temple, DE | 1 |
| Körge, K | 1 |
| Hanson, H | 1 |
| Hering, L | 1 |
| Lipso, E | 1 |
| Maramaa, S | 1 |
| Velbri, S | 1 |
| Warembourg, H | 1 |
| Ducloux, G | 1 |
| Wache, F | 1 |
| Fossati, G | 1 |
| Kobayashi, K | 1 |
| Wegmann, A | 1 |
| Renker, H | 1 |
| Húbscher, H | 1 |
| Fujiwara, M | 1 |
| Kuchii, M | 1 |
| Zacest, R | 1 |
| Koch-Weser, J | 1 |
| Watanabe, T | 1 |
| Covell, JW | 1 |
| Maroko, PR | 1 |
| Braunwald, E | 1 |
| Ross, J | 1 |
| Tsuchiya, M | 1 |
| Pascual, AV | 1 |
| London, R | 1 |
| Even, P | 1 |
| Duroux, P | 1 |
| Ruff, F | 1 |
| Caubarrere, I | 1 |
| Brouet, G | 1 |
| de Vernejoul, P | 1 |
| Spector, S | 1 |
| Fleisch, JH | 1 |
| Maling, HM | 1 |
| Brodie, BB | 1 |
| Komor, K | 1 |
| Décsy, J | 1 |
| Herpai, Z | 2 |
| Krassói, A | 2 |
| Vass, I | 2 |
| Simonyi, J | 2 |
| Brotzu, G | 1 |
| Martelli, V | 1 |
| Drost, R | 1 |
| Manz, R | 1 |
| Finsterer, U | 1 |
| Grohmann, H | 1 |
| Fénard, S | 1 |
| Farmer, JB | 1 |
| Davis, JN | 1 |
| Williams, JF | 1 |
| Childress, RH | 1 |
| Chip, JN | 1 |
| Border, JF | 1 |
| Fortenberry, B | 1 |
| Kagawa, CM | 1 |
| Leaders, FE | 1 |
| Kato, M | 1 |
| Komata, KE | 1 |
| Johnson, DG | 1 |
| Taylor, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Blood Pressure and Cardiovascular Risk With Resistance Exercise in African Americans[NCT03016351] | 140 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Hemodynamic Effect of Intrathecal Clonidine in Hypertensive Subjects: A Pilot Study to Assess Its Effectiveness in Hypertensive Subjects With Poor Blood Pressure Control (Phase II)[NCT01297335] | Phase 2 | 10 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| Plasma Catecholamine Kinetics[NCT00001329] | 50 participants | Observational | 1992-09-30 | Completed | |||
| Safety and Efficacy of Intravenous Norepinephrine for Orthostatic Hypotension[NCT01285908] | Phase 1/Phase 2 | 6 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| [NCT00005138] | 0 participants | Observational | 1976-06-30 | Completed | |||
| Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)[NCT05524987] | 1,068 participants (Anticipated) | Interventional | 2022-11-30 | Not yet recruiting | |||
| [NCT00005685] | 0 participants | Observational | 1983-09-30 | Completed | |||
| Effects of Nebivolol on Microvascular Perfusion in the Skeletal Muscles During Exercise in Hypertensive Patients[NCT01501929] | Phase 4 | 32 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Walking Intervention in African American Adults With Newly Diagnosed Hypertension[NCT00298207] | 20 participants | Interventional | 2001-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Subjects baseline blood pressure (systolic blood pressure (SBP), and diastolic blood pressure (DBP)), and blood pressures after clonidine injection was compared against baseline to assess efficacy of clonidine in refractory hypertensive subjects. Subject's blood pressure was monitored continuously after intrathecal injection of clonidine until subjects blood pressure nadir and return to pre clonidine injection level. The mean value reported below are the average changes in blood pressure from baseline (pre clonidine injection) in both SBP and DBP during post clonidine injection blood pressure monitoring for 4 hours.~Blood pressure measurements were collected every 10 minutes for first hour after injection, and every 15 minutes after the first hour, up to 4 hours were averaged to report the change from baseline." (NCT01297335)
Timeframe: Baseline, Every 10 Minutes for first hour after clonidine injection, and every 15 minutes after first hour, until 4 hours after clonidine injection
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Change in mean SBP after clonidine injection | Change in DBP after clonidine injection | |
| Intrathecal Clonidine | 79 | 37 |
Subjects were asked to rate severity of two of the most common side effects of clonidine, sedation and sensation of dry mouth, at pre and post (1 hour after) intrathecal administration of clonidine. The mean changes between pre and post injection VAS ratings of sedation and sensation of dry mouth are reported below. The VAS scale ranges from 1 to 10 cm, with higher values indicating higher level of sedation and higher level of dry mouth. (NCT01297335)
Timeframe: Before clonidine injection (Baseline), and at 1 hour after clonidine injection.
| Intervention | cm (Mean) | |
|---|---|---|
| Change in level of sedation | Change in sensation of dry mouth | |
| Intrathecal Clonidine | 3.36 | 3.47 |
Likert scale is 11 point digital pain rating system that asks subjects to rate their pain from 0 to 10. Rating of 0 means no pain at all, and in increasing order, 10 would mean worst pain imaginable/ unbearable pain. (NCT01297335)
Timeframe: Pre-dose and 1 hour post injection.
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pre-injection average Likert score | Post-injection average Likert score | |
| Intrathecal Clonidine | 6.5 | 3.6 |
Plasma levels of dihydroxyphenylglycol are obtained from blood samples via IV catheter. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | nmol/L (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 3.42 | 3.44 | 3.82 | 4.39 |
| Norepinephrine | 4.07 | 4.05 | 4.12 | 4.47 |
| Saline | 4.01 | 3.97 | 4.18 | 5.00 |
Plasma levels of norepinephrine are obtained from blood samples via IV catheter. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | nmol/L (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 0.78 | 0.89 | 1.04 | 1.3 |
| Norepinephrine | 0.73 | 1.99 | 3.73 | 7.83 |
| Saline | 0.82 | 0.65 | 0.97 | 2.32 |
The extent to which norepinephrine infusion maintains blood pressure, by comparison with the changes in diastolic pressure at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | mm Hg (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 83 | 85 | 79 | 73 |
| Norepinephrine | 95 | 95 | 92 | 98 |
| Saline | 83 | 84 | 81 | 80 |
The extent to which norepinephrine infusion maintains average blood pressure, by comparison with the fractional changes in blood pressure at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | mm Hg (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 107 | 106 | 96 | 86 |
| Norepinephrine | 123 | 121 | 116 | 124 |
| Saline | 108 | 106 | 97 | 93 |
The extent to which norepinephrine infusion maintains blood pressure, by comparison with the changes in systolic pressure at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | mm Hg (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 156 | 148 | 131 | 112 |
| Norepinephrine | 179 | 173 | 167 | 175 |
| Saline | 158 | 149 | 128 | 120 |
The extent to which norepinephrine infusion affects cardiac output, by comparison of cardiac output at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | L/min (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 4.6 | 3.9 | 3.4 | 3.4 |
| Norepinephrine | 4.9 | 5.1 | 4.6 | 4.2 |
| Saline | 3.8 | 3.5 | 3.3 | 3.2 |
The extent to which norepinephrine infusion affects cardiac stroke volume, by comparison of cardiac stroke volume at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | mL (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 76 | 70 | 62 | 52 |
| Norepinephrine | 83 | 82 | 76 | 67 |
| Saline | 66 | 62 | 56 | 50 |
The extent to which norepinephrine infusion affects heart rate, by comparison of beat-to-beat heart rate at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | bpm (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 62 | 57 | 55 | 65 |
| Norepinephrine | 58 | 60 | 59 | 63 |
| Saline | 55 | 56 | 58 | 63 |
The extent to which norepinephrine infusion affected total peripheral resistance, by comparison of total peripheral resistance at varying tilt angles during baseline and saline infusion. (NCT01285908)
Timeframe: 2 experimental days
| Intervention | mmHg/(min/L) (Mean) | |||
|---|---|---|---|---|
| Tilt Angle 0 | Tilt Angle 20 | Tilt Angle 40 | Tilt Angle 60 | |
| Baseline | 22.4 | 26.9 | 27.7 | 24.5 |
| Norepinephrine | 27 | 26 | 28 | 31 |
| Saline | 34 | 33 | 32 | 30 |
Endothelial cell (EC) was collected after a 20-guage angiocatheter was inserted into the contralateral forearm vein under sterile conditions. Three J-shaped vascular guidewires (St. Jude, St. Paul, MN) were advanced sequentially into the vein up to 10 cm. Endothelial cells were collected by gentle abrasion and placed into a dissociation buffer (0.5% bovine serum albumin, 2mM EDTA, and 100 ug/ml heparin in PBS). Endothelial cells were recovered from the tips of guide wires by repeated washing into collection tubes and subsequent centrifugation. EC were incubated with monoclonal antibodies against the polyclonal antibodies against NADPH oxidase p47 subunit. The intensity of staining was measured using fluorescence microscopy. (NCT01501929)
Timeframe: 12 weeks
| Intervention | Ratio human to HUVEC p47Phox expression (Mean) |
|---|---|
| Metoprolol | 0.47 |
| Nebivolol | 0.44 |
Microvascular perfusion of skeletal muscle were measured during handgrip at 20 cycle per minute after 12 weeks of metoprolol, and after 12 weeks of nebivolol (NCT01501929)
Timeframe: 12 weeks
| Intervention | video intensity units/ second (Median) |
|---|---|
| Metoprolol | 43.938 |
| Nebivolol | 74.584 |
22 reviews available for isoproterenol and Hypertension
| Article | Year |
|---|---|
Nitric oxide and vascular reactivity in African American patients with hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Black or African American; Brachial Artery; Carba | 2003 |
[Guidelines for the treatment of acute chemical poisoning-11-symptomatic therapy 4. Management of circulation for drug overdose and poisoning].
Topics: Acute Disease; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiac | 2007 |
Magnesium ions and contraction of vascular smooth muscles: relationship to some vascular diseases.
Topics: Animals; Calcium; Diabetes Mellitus; Humans; Hypertension; Isoproterenol; Magnesium; Magnesium Defic | 1981 |
Regression of left ventricular hypertrophy by medical treatment: present status and possible implications.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Coronary Circulation | 1983 |
[Cyclic AMP and essential arterial hypertension. Role of the adrenergic system].
Topics: Animals; Autonomic Nervous System; Cyclic AMP; Humans; Hypertension; Isoproterenol; Propranolol; Rat | 1980 |
Adrenergic receptors in the heart.
Topics: Animals; Catecholamines; Dihydroalprenolol; Humans; Hypertension; Isoproterenol; Myocardium; Recepto | 1982 |
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden, | 2000 |
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Adrenergic beta-Agonists; Animals; A | 2002 |
A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; | 1976 |
The presynaptic effect of beta-adrenoceptor antagonists on noradrenergic neurones.
Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Electric Stimulation; | 1976 |
Adrenergic beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anxiety; Cardiomyopathy, Hypertrophic; Heart; H | 1976 |
Clinical usefulness of the beta-adrenergic antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Anx | 1978 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glyc | 1976 |
The effect of hypertension, sodium, and race on isoproterenol sensitivity.
Topics: Adult; Black People; Heart Rate; Humans; Hypertension; Isoproterenol; Receptors, Adrenergic, beta; S | 1988 |
Adrenergic activity and myocardial anatomy and function in essential hypertension.
Topics: Animals; Antihypertensive Agents; Cardiomegaly; Catecholamines; Heart; Hemodynamics; Humans; Hyperte | 1985 |
Treatment of the cardiomyopathies.
Topics: Adrenergic beta-Antagonists; Alcoholism; Angina Pectoris; Anticoagulants; Atrial Fibrillation; Blood | 1973 |
[Adrenergic alpha and beta receptors and their specific inhibitors].
Topics: Action Potentials; Angina Pectoris; Arrhythmias, Cardiac; Blood Circulation; Cardiomyopathy, Hypertr | 1968 |
[Beta-receptor-blocking agents and their current clinical significance].
Topics: Adrenal Gland Neoplasms; Amino Alcohols; Angina Pectoris; Anilides; Arrhythmias, Cardiac; Blood Pres | 1968 |
[Beta-receptor-blocking agents and anesthesia].
Topics: Adrenal Gland Neoplasms; Anesthesia; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Cardiomyopathy, | 1969 |
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop | 1972 |
Drug treatment in bronchial asthma.
Topics: Acetylcysteine; Anti-Bacterial Agents; Asthma; Bronchodilator Agents; Caffeine; Drug Combinations; E | 1973 |
Propranolol.
Topics: Administration, Oral; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Blood Pressure; Cardiac Output; | 1974 |
41 trials available for isoproterenol and Hypertension
| Article | Year |
|---|---|
Effects of nonspecific beta-adrenergic stimulation and blockade on blood coagulation in hypertension.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Blood Coagulation; Cross-Over Studies; | 2003 |
Validity of pulse pressure and augmentation index as surrogate measures of arterial stiffness during beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Adult; Age Factors; Aorta; Blood Pressure; Body Height; Brachial Artery; C | 2004 |
beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine.
Topics: Acetylcholine; Adult; Arginine; Drug Synergism; Enzyme Inhibitors; Forearm; Humans; Hypertension; Is | 2004 |
Attenuation of haemodynamic, metabolic and energy expenditure responses to isoproterenol in patients with hypertension.
Topics: Adrenergic beta-Agonists; Adult; Energy Metabolism; Feasibility Studies; Female; Hemodynamics; Human | 2004 |
Comparative study with Tobanum and Visken in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; H | 1983 |
Prevention of propranolol withdrawal mechanism by prolonged small dose propranolol schedule.
Topics: Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Epineph | 1982 |
Cardioselectivity of atenolol in asthmatic patients.
Topics: Airway Resistance; Asthma; Atenolol; Clinical Trials as Topic; Double-Blind Method; Forced Expirator | 1981 |
Comparison of withdrawal phenomena after propranolol, metoprolol, and pindolol.
Topics: Adult; Aged; Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Metoprolol; Middle Age | 1982 |
Attenuation of isoproterenol-mediated vasodilatation in blacks.
Topics: Adult; Black People; Forearm; Hemodynamics; Humans; Hypertension; Infusions, Intra-Arterial; Isoprot | 1995 |
Effects of age and hypertension on adrenoceptor-sensitivity evaluated with CD25 and QT/QS2.
Topics: Adult; Aged; Aged, 80 and over; Aging; Electrocardiography; Female; Heart Rate; Humans; Hypertension | 1995 |
Systemic hypertension at 4,300 m is related to sympathoadrenal activity.
Topics: Adrenal Glands; Adult; Altitude; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Isop | 1994 |
Preserved endothelium-dependent vasodilatation in patients with essential hypertension.
Topics: Acetylcholine; Adult; Carbachol; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isopr | 1994 |
The combination of epinephrine and isoproterenol as a simulated epidural test dose in isoflurane-anesthetized adults.
Topics: Adrenergic Agonists; Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Blood V | 1998 |
Age, hypertension, and cardiac responses to beta-agonist in humans.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Antihypertensive Agents; Blood Pressure; Catecholamine | 1998 |
Impaired force-frequency relations in patients with hypertensive left ventricular hypertrophy. A possible physiological marker of the transition from physiological to pathological hypertrophy.
Topics: Adrenergic beta-Agonists; Adult; Biomarkers; Cardiac Pacing, Artificial; Epinephrine; Exercise; Hear | 1999 |
Psychological states and lymphocyte beta-adrenergic receptor responsiveness.
Topics: Adrenergic beta-Agonists; Adult; Affect; Anger; Anxiety; B-Lymphocytes; Cyclic AMP; Depression; Fema | 1999 |
Quinapril treatment enhances vascular sensitivity to insulin.
Topics: Adrenergic beta-Agonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pres | 2001 |
Baroreflex buffering and susceptibility to vasoactive drugs.
Topics: Adrenergic beta-Agonists; Adult; Baroreflex; Blood Pressure; Diet; Dose-Response Relationship, Drug; | 2002 |
Plasma levels and effects of metoprolol on blood pressure, adrenergic beta receptor blockade, and plasma renin activity in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Isopro | 1976 |
Hemodynamic effects of labetalol, an alpha and beta adrenergic blocking agent, in hypertensive subjects.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amyl Nitrite; Blood Pressure; Card | 1977 |
Management of hypertension. Clinical and hemodynamic studies with special reference to patients refractory to treatment.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Attitude to Health; Blood Pressure Determinati | 1977 |
Reduction of plasma renin activity by inhibition of the fatty acid cyclooxygenase in human subjects: independence of sodium retention.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Cycloox | 1979 |
Effect of selective and non-selective beta-adrenoreceptor blockade on calf blood flow in hypertensive patients.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Isoproterenol; Leg; Metoprolol; Propanolamines; Pr | 1978 |
Comparative potency of atenolol and propranolol as beta-adrenergic blocking agents in man.
Topics: Adult; Atenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Female | 1976 |
Role of the autonomic nervous system in mild human hypertension.
Topics: Adolescent; Adult; Autonomic Nervous System; Blood Pressure; Cardiac Output; Clinical Trials as Topi | 1975 |
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabet | 1992 |
Modulation of noradrenergic but not angiotensinergic blood pressure control by beta-blockade with carteolol.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Carteolol; Female; Humans; Hyperte | 1991 |
Beta-adrenergic receptor sensitivity during sodium restriction and converting enzyme inhibition.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Combined | 1990 |
Celiprolol, atenolol and propranolol: a comparison of pulmonary effects in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Asthma; Atenolol; Celiprolol; Forced Expiratory Volume; Humans; Hyperte | 1986 |
Reversal of cardiac hypertrophy by long-term treatment with calcium antagonists in hypertensive patients.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Catecholamines; Female; Heart; Heart | 1988 |
Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Catecholamines; | 1989 |
Cardiovascular regulation and lipoprotein profile during administration of co-dergocrine in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Dihydroergotoxine; Female; Glomerular Filtrati | 1989 |
Compound ICI 118,551, a beta 2-adrenoceptor antagonist, lowers blood pressure.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Humans; Hypertension; Isopr | 1985 |
Cardiovascular effects of verapamil in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Delayed-Action Prepara | 1987 |
[Comparative studies on propranolol and practolol].
Topics: Adrenergic beta-Antagonists; Cardiac Output; Clinical Trials as Topic; Heart Rate; Humans; Hypertens | 1973 |
Beta-adrenergic blockade in essential hypertension. Effects of propranolol on hemodynamic parameters and plasma renin activity.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Depress | 1973 |
Clinical evaluation of indoramin, a new antihypertensive agent.
Topics: Angiotensin II; Antihypertensive Agents; Benzamides; Blood Pressure; Body Weight; Clinical Trials as | 1973 |
Beta-adrenergic blocking therapy in hypertension: selection of patients.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Blood Volume; Body Surface Area; Cardiac Output; | 1970 |
The effct of propranolol on plasma renin activity and blood pressure in mild essential hypertension.
Topics: Administration, Oral; Adult; Aged; Black People; Blood Pressure; Clinical Trials as Topic; Creatinin | 1974 |
Effects of isoproterenol and isoproterenol-phenylephrine aerosols on hypertensive asthmatic patients.
Topics: Adult; Aerosols; Aged; Asthma; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertensio | 1968 |
Hyperdynamic beta-adrenergic circulatory state. Increased beta-receptor responsiveness.
Topics: Adult; Autonomic Nervous System; Blood Circulation; Blood Pressure; Cardiac Output; Cardiovascular D | 1969 |
475 other studies available for isoproterenol and Hypertension
| Article | Year |
|---|---|
Structural basis and mechanism of activation of two different families of G proteins by the same GPCR.
Topics: Animals; Cardiac Output; Cell Line; Cryoelectron Microscopy; Cyclic AMP; Enzyme Activation; GTP-Bind | 2021 |
Metabolomics analysis delineates the therapeutic effects of hydroethanolic extract of Cucumis sativus L. seeds on hypertension and isoproterenol-induced myocardial infarction.
Topics: Animals; Cucumis sativus; Hypertension; Isoproterenol; Metabolomics; Myocardial Infarction; Myocardi | 2022 |
Topics: Adult; Angiotensin II; Animals; Athletic Performance; Blood Pressure; COVID-19; Diabetes Mellitus; H | 2022 |
Dynein Coordinates β2-Adrenoceptor-Mediated Relaxation in Normotensive and Hypertensive Rat Mesenteric Arteries.
Topics: Animals; Colchicine; Dyneins; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Rats; Rats, In | 2022 |
Impaired vascular β-adrenergic relaxation in spontaneously hypertensive rats: The differences between conduit and resistance arteries.
Topics: Adrenergic Agents; Adrenergic beta-Agonists; Animals; Endothelium, Vascular; Hypertension; Isoproter | 2023 |
BDNF downregulates β-adrenergic receptor-mediated hypotensive mechanisms in the paraventricular nucleus of the hypothalamus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Brain-Derived Neurotrophic Factor; D | 2019 |
Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Cannabidiol; Carbachol; Cell Size; Coron | 2021 |
Higenamine attenuates cardiac fibroblast abstract and fibrosis via inhibition of TGF-β1/Smad signaling.
Topics: Actins; Adrenergic beta-Agonists; Alkaloids; Animals; Aorta; Apoptosis; Cardiomegaly; Fibrinolytic A | 2021 |
Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction.
Topics: Administration, Oral; Animals; Antioxidants; Drug Carriers; Hypertension; Isoproterenol; Isradipine; | 2022 |
Sub-chronic lead exposure produces β
Topics: Animals; Arterial Pressure; Cardiovascular Diseases; Down-Regulation; Heart Rate; Hexamethonium; Hyp | 2017 |
Limited Impact of β-Adrenergic Receptor Activation on Left Ventricular Diastolic Function in Rat Models of Hypertensive Heart Disease.
Topics: Adrenergic beta-Agonists; Animals; Diastole; Disease Models, Animal; Echocardiography, Doppler, Puls | 2018 |
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Fibrosis; Glomerular Filtration Rate; H | 2019 |
Involvement of BKCa and KV potassium channels in cAMP-induced vasodilatation: their insufficient function in genetic hypertension.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cyclic AMP; Hypertension; Isoproterenol; Large-Co | 2014 |
Cardiovascular function alterations induced by acute paradoxical sleep deprivation in rats.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Baroreflex; Blood Pressure; Heart | 2014 |
The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Caffeic Acids; Disease Models, Animal; Hypertension; Injectio | 2014 |
Angiotensin II receptor blockers decrease serum concentration of fatty acid-binding protein 4 in patients with hypertension.
Topics: 3T3 Cells; Adrenergic beta-Agonists; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Animals; A | 2015 |
Energy Deregulation Precedes Alteration in Heart Energy Balance in Young Spontaneously Hypertensive Rats: A Non Invasive In Vivo31P-MR Spectroscopy Follow-Up Study.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Energy Metabolism; Follow-Up Studies; Hea | 2016 |
Modulation of systemic and aortic nitric oxide by melatonin and n-3 polyunsaturated fatty acids in isoproterenol affected spontaneously hypertensive and normotensive Wistar rats.
Topics: Animals; Antioxidants; Aorta; Dietary Supplements; Drug Evaluation, Preclinical; Fatty Acids, Omega- | 2016 |
Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Calcium Channels; Constriction, Pathologic | 2017 |
Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agoni | 2017 |
The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism.
Topics: Animals; Antihypertensive Agents; Cardiomyopathies; Cardiotonic Agents; Chromogranin A; Coronary Cir | 2008 |
Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Dopamine; Hemodyna | 2008 |
Modification of atrial natriuretic peptide system in cold-induced hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Atrial Natriu | 2009 |
Effect of preischemic beta-adrenoceptor stimulation on postischemic contractile dysfunction.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Female; Hemodynamics; Hyperte | 2009 |
Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function.
Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Experimenta | 2009 |
Leptin reduces plasma ANP level via nitric oxide-dependent mechanism.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Carotid Arteries; Hypertension; Isoproterenol; J | 2010 |
Maternal low-protein diet during mouse pre-implantation development induces vascular dysfunction and altered renin-angiotensin-system homeostasis in the offspring.
Topics: Animals; Arteries; Blood Pressure; Bronchodilator Agents; Diet, Protein-Restricted; Female; Homeosta | 2010 |
Enhanced GRK2 expression and desensitization of betaAR vasodilatation in hypertensive patients.
Topics: Adult; Female; Forearm; G-Protein-Coupled Receptor Kinase 2; Heparin; Humans; Hypertension; Isoprote | 2008 |
Impact of aldosterone receptor blockade on the deleterious cardiac effects of adrenergic activation in hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Blood Pressure; Cardiomyopathy, Dilated; Hypertension; | 2010 |
The effects of high dietary lard on hypertension development in spontaneously hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Baroreflex; | 2010 |
Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Gluc | 2010 |
Regulation of 3',5'-cAMP in preglomerular smooth muscle and endothelial cells from genetically hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonist | 2010 |
In vivo decrease of adenylate cyclase responsiveness to isoproterenol in the spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cyclic AMP; Dose-Response Relationship, Drug; | 1981 |
Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs.
Topics: Acetanilides; Adrenergic Antagonists; Animals; Autonomic Agents; Coronary Circulation; Dogs; Dose-Re | 2011 |
Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor-mediated relaxation of renal arteries in hypertension.
Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Kn | 2012 |
Impaired β-adrenoceptor-induced relaxation in small mesenteric arteries from DOCA-salt hypertensive rats is due to reduced K(Ca) channel activity.
Topics: Adrenergic beta-Agonists; Alkanes; Animals; Desoxycorticosterone; GTP-Binding Proteins; Hypertension | 2012 |
The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli.
Topics: Angiotensin I; Animals; Cardiomegaly; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Motor | 2012 |
Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiomegaly; Endomyocardial Fibrosis; G-Prote | 2012 |
Functional beta1- and beta2-adrenoceptors in the left and right atrium of pre-hypertensive rats.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Recep | 2002 |
Beta3 adrenergic stimulation inhibits the opossum lower esophageal sphincter.
Topics: Adrenergic beta-3 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino | 2002 |
A decrease in the amount and function of the stimulatory GTP-binding protein in the small resistance arteries of spontaneously hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Arteries; Blood Pressure; GTP-Binding Protein alpha Subunits, Gs; | 2002 |
Chronic antioxidant treatment improves sympathetic functions and beta-adrenergic pathway in the spontaneously hypertensive rats.
Topics: Acetylcysteine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Antioxidants; Aorta; Binding S | 2003 |
Beta-adrenergic activation initiates chamber dilatation in concentric hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Collagen; Dilatation, Pathologic; Di | 2003 |
Inherited adrenocorticotropin-independent macronodular adrenal hyperplasia with abnormal cortisol secretion by vasopressin and catecholamines: detection of the aberrant hormone receptors on adrenal gland.
Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenergic beta-Agonists; Adrenocor | 2002 |
Thoracic massage permits use of echocardiography in unanesthetized rats.
Topics: Anesthesia; Animals; Cardiotonic Agents; Consciousness; Echocardiography; Heart Massage; Heart Ventr | 2003 |
[Experimental research on the new aludrine-like broncholytic agent Alupent, with special reference to circulatory reactions in hypertensives].
Topics: Bronchi; Bronchial Diseases; Bronchodilator Agents; Disease; Hypertension; Isoproterenol; Metaproter | 1961 |
The hemodynamic effects of isoproterenol on pulmonary hypertension in man.
Topics: Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Isoproterenol; Male | 1963 |
Vascular reactivity of reserpine-pretreated dogs.
Topics: Acetylcholine; Animals; Blood Vessels; Dogs; Histamine; Hypertension; Isoproterenol; Nitroglycerin; | 1963 |
THE LUNG AS THE MAIN TARGET ORGAN IN THE ACUTE PHASE OF TRANSFUSION REACTION IN SHEEP.
Topics: Animals; Apnea; Blood Group Incompatibility; Blood Transfusion; Heart Function Tests; Heart, Artific | 1963 |
[METABOLISM OF SEROTONIN. IV. DEPLETING EFFECT OF GM-16462].
Topics: Biliary Dyskinesia; Bronchitis; Glomerulonephritis; Heart Diseases; Hypertension; Isoproterenol; Leu | 1963 |
ARTIFICIAL ELECTRICAL PACING FOR HEART BLOCK: A REVIEW BASED ON TWENTY-FOUR CASES TREATED WITH IMPLANTED PACEMAKERS.
Topics: Adams-Stokes Syndrome; Cardiac Surgical Procedures; Coronary Disease; Ephedrine; Epinephrine; Heart | 1964 |
SURGICAL TREATMENT OF COMPLETE HEART BLOCK. AN ANALYSIS OF 36 CASES.
Topics: Atropine; Chlorothiazide; Diabetes Mellitus; Ephedrine; Geriatrics; Heart Block; Heart Failure; Huma | 1964 |
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr | 1964 |
[INFLUENCE OF 1-(3,4-DICHLOROPHENYL)-2-ISOPROPYLAMINOETHANOL (DCI) ON THE COURSE OF HYPERTENSION OBTAINED BY CONTINUOUS ADRENALINE PERFUSION].
Topics: Dogs; Epinephrine; Ethanolamines; Hypertension; Hypotension; Isoproterenol; Perfusion; Pharmacology; | 1964 |
ISOPROTERENOL AND CARDIOVASCULAR PERFORMANCE.
Topics: Aortic Valve Stenosis; Biomedical Research; Blood Pressure; Cardiac Catheterization; Coronary Diseas | 1964 |
Responsiveness, affinity constants and beta 2-adrenoceptor reserves for isoprenaline on portal veins from normo- and pre- and hypertensive rats.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Binding Sites; Dose-Response Relationship, Drug; Hyper | 2003 |
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aorti | 2004 |
Do acute changes in heart rate by isoproterenol affect aortic stiffness in patients with hypertension?
Topics: Aged; Aorta; Chest Pain; Coronary Disease; Elasticity; Female; Heart Rate; Humans; Hypertension; Iso | 2004 |
AKT participates in endothelial dysfunction in hypertension.
Topics: Acetylcholine; Adenoviridae; Animals; Aorta; Carotid Artery, Common; Cell Membrane; Cells, Cultured; | 2004 |
Catecholamine-induced regulation in vitro and ex vivo of intralymphocyte ionized magnesium.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Catecholamines; Epinephrine; Female; Fura-2; | 2004 |
A phosphodiesterase inhibitor promotes the premature development of adverse cardiac remodelling mediated by beta-adrenergic activation in hypertension.
Topics: Adrenergic beta-Agonists; Animals; Collagen; Dilatation, Pathologic; Drug Therapy, Combination; Echo | 2004 |
Aldosterone receptor blockade prevents the transition to cardiac pump dysfunction induced by beta-adrenoreceptor activation.
Topics: Adrenergic beta-Agonists; Animals; Collagen; Echocardiography; Heart; Hypertension; Hypertrophy, Lef | 2005 |
Improved myocardial beta-adrenergic responsiveness and signaling with exercise training in hypertension.
Topics: Adrenergic beta-Agonists; Animals; beta-Adrenergic Receptor Kinases; Blood Pressure; Calcium Channel | 2005 |
Signal transduction involving Ras-GTPase contributes to development of hypertension and end-organ damage in spontaneously hypertensive rats-treated with L-NAME.
Topics: Animals; Blood Pressure; Collagen Type III; Hypertension; Isoproterenol; Kidney; Myocardial Reperfus | 2005 |
Contribution of cytochrome P450 metabolites of arachidonic acid to hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME.
Topics: Animals; Arachidonic Acid; Blood Pressure; Blood Vessels; Collagen Type III; Coronary Vessels; Cytoc | 2005 |
The impact of blunted beta-adrenergic responsiveness on growth regulatory pathways in hypertension.
Topics: Adrenergic beta-Agonists; Animals; Base Sequence; Cell Proliferation; Cells, Cultured; Colforsin; DN | 2006 |
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GT | 2005 |
Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension.
Topics: Aldehydes; Animals; Blood Pressure; Cardiotonic Agents; Desoxycorticosterone; Heart; Hypertension; H | 2005 |
Does central nitric oxide elicit pulmonary hypertension in conscious rats?
Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Pressure; Enzyme Inhibitors; Heart Ra | 2006 |
Effects of Ginkgo biloba extract feeding on salt-induced hypertensive Dahl rats.
Topics: Acetylcholine; Administration, Oral; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressu | 2006 |
Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Age Factors; Animals; Ethanolamines; | 2006 |
Mechanism behind augmentation in baroreflex sensitivity after acute exercise in spontaneously hypertensive rats.
Topics: Animals; Baroreflex; Blood Pressure; Cardiotonic Agents; Heart Rate; Hypertension; Isoproterenol; Ma | 2006 |
Coronary reactive hyperaemia and arterial pressure in anaesthetized goats.
Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Coronary Vessels; Female; Goats; Heart; Hyperemia | 2006 |
Effects of forskolin on inotropic performance and phospholamban phosphorylation in exercise-trained hypertensive myocardium.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium-Binding Proteins; Colf | 2007 |
[Characteristics of neuronal activity in nucleus accumbens in spontaneously hypertensive rats].
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Hypertension; Iontophoresis; Isoproterenol; Mi | 2007 |
Sympathoadrenal function in patients with paroxysmal hypertension: pseudopheochromocytoma.
Topics: Adrenal Glands; Adult; Baroreflex; Blood Pressure Monitoring, Ambulatory; Epinephrine; Female; Gluca | 2007 |
Susceptibility to systolic dysfunction in the myocardium from chronically infarcted spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Disease Models, Animal; Hypertension; Isop | 2008 |
[Isoproterenol regulates lipopolysaccharide-induced tumor necrosis factor-alpha and interleukin-6 production in monocytes from essential hypertensive patients.].
Topics: Adult; Case-Control Studies; Cells, Cultured; Humans; Hypertension; Interleukin-6; Isoproterenol; Ma | 2007 |
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
Topics: Animals; Arterioles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Anima | 2008 |
Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Cell Line; Cells | 2008 |
Haemodynamic effects of propranolol.
Topics: Adult; Aged; Atropine; Heart Rate; Humans; Hypertension; Isoproterenol; Middle Aged; Myocardial Infa | 1967 |
Increase of cardiac beta-adrenergic receptors in young spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cyclic AMP; Hypertension; Isoproterenol; Male; Myocardium; Pindolol; Rats; | 1984 |
Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Cyclic AMP; Hypertension; Isoproterenol; Male; Propranolol; Rats; Ra | 1984 |
Effect of isoproterenol on vascular adrenergic neurotransmission in prehypertensive and hypertensive spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Hypertension; Isoproterenol; Male; Mesenteric Arteries; | 1984 |
Increased density and responsiveness of alpha 2 and beta-adrenoceptors in circulating blood cells of essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Blood Platelets; Epinephrine; Humans; Hypertension; Iodocyanopindolol; Isop | 1984 |
Peripheral vascular smooth muscle relaxation in normotensive and hypertensive rats.
Topics: Adenosine; Animals; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Mu | 1980 |
Heterocyclic analogues of the antihypertensive beta-adrenergic blocking agent (S)-2-[3-(ter-butylamino)-2-hydroxypropoxy]-3-cyanopyridine.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Heart R | 1980 |
Pre- and postjunctional beta-adrenoceptor mediated effects on transmitter release and effector response in the isolated rat portal vein.
Topics: Animals; Autacoids; Electric Stimulation; Female; Hypertension; Isoproterenol; Male; Metoprolol; Mus | 1980 |
[Exogenous adrenergic stimulation by intravenous infusions of isoproterenol and blood levels of cyclic AMP before and after beta-blocking in humans].
Topics: Adrenergic beta-Antagonists; Adult; Cyclic AMP; Cyclic GMP; Ethanolamines; Female; Humans; Hypertens | 1980 |
Enhanced presynaptic beta adrenoceptor-mediated modulation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Blood Pressure; Blood Vessels; Electric Stimulation | 1982 |
Alpha-adrenoceptor blockade by labetalol during long-term dosing.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Ethanolamines | 1983 |
[Acute tolerance to the hypotensive effect of pindolol in spontaneously hypertensive rats (SHR)].
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drug T | 1983 |
Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Dihydroalprenolol; Dioxanes; Heart Ventricles; Hyperte | 1984 |
Antihypertensive effect and degree of beta-adrenoceptor blockade after short-term and semi-chronic propranolol therapy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Electrolytes; Female; H | 1984 |
Involvement of the vascular renin-angiotensin system in beta adrenergic receptor-mediated facilitation of vascular neurotransmission in spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenergic beta-Antagonists; Angiotensin I; Animals; Blood | 1984 |
Pressor response to beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Female; Humans; Hypertension; Isoproterenol; | 1984 |
Dissociation of the effects of alpha 1-adrenergic blockade on blood pressure and renin release in patients with essential hypertension.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Blood Pressure; Humans; Hypertension; Isoproterenol | 1982 |
Studies on concurrent alpha- and beta-adrenoceptor blocking action of S-596 (arotinolol).
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiac Outp | 1983 |
Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol.
Topics: Amine Oxidase (Copper-Containing); Animals; Cardiomegaly; Hypertension; Isoproterenol; Male; Muscle | 1983 |
[Pathophysiology of asymmetric septal hypertrophy with special reference to the response to isoproterenol administration].
Topics: Adult; Aged; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female; Heart Septum; Hum | 1984 |
Activity of cyclic AMP-dependent protein kinase in heart and aorta of spontaneously hypertensive rat.
Topics: Age Factors; Animals; Aorta; Cyclic AMP; Hypertension; In Vitro Techniques; Isoproterenol; Male; Myo | 1980 |
Plasma catecholamines and cardiac, renal and peripheral vascular adrenoceptor-mediated responses in different age groups of normal and hypertensive subjects.
Topics: Adult; Aging; Epinephrine; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney; Middle Aged; Nor | 1980 |
Ontogenetic development of isoproterenol subsensitivity of myocardial adenylate cyclase and beta-adrenergic receptors in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Cell Membrane; Dihydroalprenolol; Heart; Hypertensio | 1980 |
Peripheral beta-adrenoceptor responsiveness in young normotensive and hypertensive subjects.
Topics: Adult; Blood Pressure; Cardiovascular System; Fatty Acids, Nonesterified; Heart Rate; Humans; Hypert | 1981 |
A comparison of cardiac reactivity and beta-adrenoceptor number and affinity between aorta-coarcted hypertensive and normotensive rats.
Topics: Animals; Heart Rate; Hypertension; Isoproterenol; Male; Myocardial Contraction; Myocardium; Norepine | 1981 |
Contribution of cardiovascular reflexes to differences in beta-adrenoceptor-mediated responses in essential hypertension.
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Blood Pressure; Clonidine; Heart Rate; Humans; Hy | 1981 |
Altered inotropic responsiveness to isoproterenol of hearts from spontaneously hypertensive rats during development.
Topics: Age Factors; Animals; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; Myocardial C | 1982 |
Reduced beta adrenoceptor interactions of norepinephrine enhance contraction in the femoral artery from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Female; Femoral Artery; Hypertension; In Vitro Techniques; Isoproterenol; | 1982 |
[Labile essential hypertension. The effect of Isoprenaline Spofa on plasma level of cyclic adenosine monophosphate].
Topics: Adult; Blood Pressure; Cyclic AMP; Humans; Hypertension; Isoproterenol; Male | 1982 |
The ratio of cardiac to vascular beta-receptor blockade of atenolol and propranolol in spontaneously hypertensive rats in vivo.
Topics: Animals; Atenolol; Blood Vessels; Female; Heart; Hemodynamics; Hypertension; Isoproterenol; Propanol | 1982 |
Estimated affinity of isoproterenol to cardiac chronotropic beta-receptor and of phenylephrine to vasoconstrictive alpha-receptor of the systemic resistance vessels in human borderline hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Epinephrine; Female; Heart Rate; Humans; Hypertension; Isopro | 1983 |
Ageing as a factor governing the effect of isoproterenol on the cyclic AMP level in isolated aorta from spontaneously hypertensive and normotensive rats.
Topics: Aging; Animals; Aorta; Cyclic AMP; DNA; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats | 1983 |
Effects of oral salt loading on beta-adrenergic receptor responsiveness in normal and hypertensive subjects.
Topics: Adolescent; Adult; Blood Glucose; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Insulin; | 1982 |
Isoprenalin effect on plasma cAMP and blood pressure in labile essential hypertension.
Topics: Adult; Blood Pressure; Cyclic AMP; Dopamine beta-Hydroxylase; Heart Rate; Humans; Hypertension; Isop | 1982 |
The activity of adenylate cyclase and phosphodiesterase in the isoproterenol-damaged cardiac muscle of spontaneously hypertensive rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cardiomyopathies; Cell Membrane; Cy | 1983 |
Mechanism of the increased cardiac Ca2+ uptake induced by isoprenaline in DOCA-salt pretreated rats.
Topics: Adenylyl Cyclases; Animals; Calcium; Cyclic AMP; Desoxycorticosterone; Electrolytes; Hypertension; I | 1984 |
Leukocyte beta-receptor alterations in hypertensive subjects.
Topics: Adenylyl Cyclases; Adult; Binding, Competitive; Epinephrine; Humans; Hypertension; Isoproterenol; Le | 1984 |
An altered beta-adrenoreceptor-mediated modulation of noradrenaline-induced vasoconstriction in spontaneously hypertensive rat mesenteric arteries.
Topics: Animals; Hypertension; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Norepinephrine | 1984 |
Relationships between left ventricular mass and clinical, biohumoral and hemodynamic parameters in human hypertension.
Topics: Adolescent; Adult; Age Factors; Animals; Cardiomegaly; Catecholamines; Echocardiography; Heart Rate; | 1984 |
Beta 1 - beta 2 blocking activity of propranolol and metoprolol in the unanaesthetized genetically hypertensive and normotensive rat.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Isoproterenol; Male; Metoprolol; Pressoreceptors; | 1984 |
[Study of the mechanisms of impaired beta-receptor responsiveness in arterial hypertension].
Topics: Adolescent; Adult; Cyclic AMP; Epinephrine; Heart Rate; Humans; Hypertension; Isoproterenol; Male; N | 1983 |
Pressor responses of rats to vasopressin: effect of sodium, angiotensin, and catecholamines.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hypertension; | 1983 |
Plasma vasopressin in rats: effect of sodium, angiotensin, and catecholamines.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Captopril; Hypertension; Isoproterenol; Male; Norepin | 1983 |
Coronary artery reactivity in deoxycorticosterone acetate hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Arteries; Coronary Vessels; Desoxycorticosterone; Epoprostenol; H | 1984 |
Blood pressure responsiveness to isoproterenol during the development of hypertension in conscious, spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Hypertension; Isoprotereno | 1984 |
Effect of high blood pressure stress on vascular adrenergic responsiveness in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Hypertension; Iliac Artery; Isoproterenol; Ligation; Male; Norepinephrine; | 1984 |
[Adaptative cardiac changes in arterial hypertension].
Topics: Adaptation, Physiological; Animals; Blood Pressure; Cell Membrane; Disease Models, Animal; Heart Rat | 1984 |
Correction of cardiovascular hypersensitivity to norepinephrine by potassium supplementation in normotensive members of hypertensive families and patients with essential hypertension.
Topics: Adult; Blood Pressure; Cardiovascular System; Disease Susceptibility; Dose-Response Relationship, Dr | 1984 |
Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension.
Topics: Adult; Carbon Radioisotopes; Desipramine; Humans; Hypertension; Isoproterenol; Metabolic Clearance R | 1983 |
Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension.
Topics: Adult; Carbon Radioisotopes; Desipramine; Humans; Hypertension; Isoproterenol; Metabolic Clearance R | 1983 |
Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension.
Topics: Adult; Carbon Radioisotopes; Desipramine; Humans; Hypertension; Isoproterenol; Metabolic Clearance R | 1983 |
Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension.
Topics: Adult; Carbon Radioisotopes; Desipramine; Humans; Hypertension; Isoproterenol; Metabolic Clearance R | 1983 |
Predictability of antihypertensive efficacy of selective beta 1 blockers.
Topics: Adult; Aldosterone; Atenolol; Blood Pressure; Cardiac Output; Catecholamines; Echocardiography; Fema | 1983 |
Cardiovascular injury from blunt thoracic impact of epinephrine and isoproterenol injected rabbits.
Topics: Animals; Blood Pressure; Epinephrine; Heart Injuries; Heart Ventricles; Hypertension; Hypotension; I | 1983 |
Study of the Adrenergic reactivity of the anococcygeal muscle in spontaneously hypertensive rats.
Topics: Age Factors; Anal Canal; Animals; Female; Hypertension; Isoproterenol; Male; Muscle Contraction; Mus | 1983 |
Intracellular free [Ca2+] in circulating lymphocytes of spontaneously hypertensive rats.
Topics: Animals; Calcium; Female; Hypertension; Isoproterenol; Kinetics; Lymphocytes; Male; Norepinephrine; | 1984 |
[Effects of salt loading on the response to isoproterenol in normal and hypertensive subjects].
Topics: Adolescent; Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Insulin; Isoproterenol; | 1982 |
Vasodilator responses to cholinergic and adrenergic stimulants in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) normotensive rats.
Topics: Animals; Blood Pressure; Ferricyanides; Heart Rate; Hypertension; Isoproterenol; Male; Methacholine | 1983 |
Detection of acute myocardial infarction in spontaneously hypertensive rats by 99mTc-pyrrolidino methyl tetracycline.
Topics: Animals; Disease Models, Animal; Female; Hypertension; Isoproterenol; Male; Myocardial Infarction; M | 1983 |
Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats.
Topics: Animals; Body Weight; Bromocriptine; Electrocardiography; Female; Heart Rate; Hormones; Hypertension | 1983 |
[Apical hypertrophic cardiomyopathy: variability in the amplitude of T-wave inversion and distribution of the left ventricular mass].
Topics: Cardiomyopathy, Hypertrophic; Electrocardiography; Exercise Test; Female; Heart Ventricles; Humans; | 1982 |
[Effects of saline load on the response to isoproterenol in normal and hypertensive subjects].
Topics: Adolescent; Adult; Blood Pressure; Blood Volume; Female; Heart Rate; Humans; Hypertension; Isoproter | 1982 |
Effects of different stages of aortic coarctation hypertension on aortic contraction and relaxation in rats.
Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Body Weight; Hypertension; Isoproterenol; Ligatio | 1980 |
Adrenergic responsiveness in prehypertensive subjects.
Topics: Adolescent; Adult; Blood Pressure; Follow-Up Studies; Heart Rate; Humans; Hypertension; Isoprotereno | 1982 |
The role of the adrenergic system in hypertension after renal transplantation.
Topics: Blood Pressure; Blood Volume; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney Transp | 1981 |
Estimation of sympathetic activity in essential hypertension.
Topics: Blood Pressure; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Kinetics; Male; Middle Aged | 1982 |
Characteristics of hormone-stimulated adenylate cyclase in vascular smooth muscle: altered activity in spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Animals; Aorta; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hyperte | 1982 |
Studies on the autonomic nervous system in borderline hypertension.
Topics: Adolescent; Adult; Autonomic Nervous System; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypert | 1982 |
Changes of lipid peroxides and alpha-tocopherol in rats with experimentally induced myocardial necrosis.
Topics: Animals; Cholesterol; Heart; Hypertension; Isoproterenol; Lipid Peroxides; Liver; Male; Myocardium; | 1982 |
Paradoxical relationship between the superior cervical ganglia and the antihypertensive action of propranolol in the spontaneous hypertensive rat.
Topics: Animals; Blood Pressure; Denervation; Ganglia, Sympathetic; Heart Rate; Hypertension; Isoproterenol; | 1982 |
Elevated plasma catecholamines without alteration in cardiovascular responsiveness in young men with borderline hypertension.
Topics: Adult; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Isoproterenol; Norepinephrine; | 1982 |
Decreased chronotropic responses to adrenergic stimulation following sinoaortic denervation in the rat.
Topics: Acoustic Stimulation; Anesthetics; Animals; Behavior, Animal; Denervation; Depression, Chemical; Hea | 1982 |
Secretin and VIP-stimulated adenylate cyclase from rat heart. II. Impairment in spontaneous hypertension.
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Hy | 1980 |
Age-dependent changes in the myocardial adenylate cyclase of normotensive and spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Hypertension; Isoproterenol; Male; Microsomes; Muscl | 1981 |
Metabolic responsiveness of spontaneously hypertensive rat to isoproterenol.
Topics: Animals; Blood Glucose; Body Temperature; Dose-Response Relationship, Drug; Heart Rate; Hypertension | 1981 |
Isoproterenol-induced cardiac failure in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiac Output; Heart Failure; Heart Rate; Hemodynamics; Hypertension; Isop | 1981 |
Isoproterenol in primary hypertension.
Topics: Humans; Hypertension; Isoproterenol; Vasodilator Agents | 1980 |
[Myocardial phosphorylase activity in rats with spontaneous and metacorticoid hypertension treated with isoprenaline and untreated].
Topics: Animals; Enzyme Activation; Female; Hypertension; Isoproterenol; Male; Myocardium; Nephrectomy; Phos | 1980 |
Electromagnetic flow-probe implantation for cardiac output measurements in rabbits.
Topics: Animals; Cardiac Output; Electromagnetic Phenomena; Female; Hemodynamics; Hypertension; Isoprotereno | 1980 |
Technical and pharmacologic management of distal hypotension during repair of coarctation of the aorta.
Topics: Aortic Coarctation; Child; Humans; Hypertension; Hypotension; Hypotension, Controlled; Intraoperativ | 1980 |
[Effect of isoproterenol on adenylate cyclase activity in the adipocytes of rats with spontaneous genetic hypertension].
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenalectomy; Animals; Enzyme Activation; Hypertension; Isoprote | 1980 |
Influence of propranolol and pindolol on the haemodynamic effects of papaverine, isoprenaline and noradrenaline in hypertensive patients.
Topics: Adult; Blood Pressure; Drug Interactions; Heart Rate; Hemodynamics; Humans; Hypertension; Isoprotere | 1980 |
Cardiac contractile reserve in spontaneously hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Isoproterenol; Male; Myocardial | 1980 |
Forskolin-stimulated adenylyl cyclase activity is decreased but beta 2-adrenoceptor function is unchanged in primary hypertension.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Binding, Competitive; Cell Membrane; Colforsi | 1993 |
Mechanisms of cardiac cell damage due to catecholamines: significance of drugs regulating central sympathetic outflow.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Catecholamines; Clo | 1994 |
Changes in sympathetic neurotransmission and adrenergic control of cardiac contractility during 1,3-dipropyl-8-sulfophenylxanthine-induced hypertension.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Depression, Chemical; Dis | 1995 |
[Ca2+]i transients in hypertensive and postinfarction myocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiac Pacing, Artificial; Cell Separation; Diastole; F | 1995 |
[Decrease in adenylate cyclase sensitivity to sodium ions in lymphocytes of patients with arterial hypertension].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Catecholamines; Enzyme Activation; GTP-Binding Prote | 1995 |
G protein alterations in hypertension and aging.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aging; Aluminum Compoun | 1995 |
Hypertension and enhanced beta-adrenoceptor-mediated facilitation of noradrenaline release produced by chronic blockade of adenosine receptors.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Isoproteren | 1995 |
Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure.
Topics: Animals; Biochemical Phenomena; Biochemistry; Colforsin; Heart Failure; Heart Ventricles; Hypertensi | 1995 |
Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension.
Topics: Adult; Endothelium, Vascular; Forearm; Humans; Hypertension; Isoproterenol; Male; Norepinephrine; Re | 1995 |
Cerebral reactive hyperaemia and arterial pressure in anaesthetized goats.
Topics: Anesthesia; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Cerebrovascular Circulation; Female; | 1995 |
Reduced beta 2-receptor mediated vasodilation in African Americans.
Topics: Adult; Black or African American; Blood Pressure; Cardiovascular Diseases; Dose-Response Relationshi | 1995 |
cAMP and protein synthesis in isolated adult rat heart preparations.
Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Depende | 1993 |
Angiotensin II and sympathetic activity in sodium-restricted essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Diet, | 1995 |
Vasomotor reactivity and catecholamine, arginine vasopressin plasma levels during ageing and development in rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery | 1994 |
Beta 2-adrenergic receptor characteristics in sleep apnea patients.
Topics: Adenosine Monophosphate; Adrenergic beta-Antagonists; Adult; Humans; Hypertension; Isoproterenol; Mi | 1995 |
Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27).
Topics: Animals; Animals, Genetically Modified; Hypertension; Isoproterenol; Male; Mice; Myocardial Contract | 1995 |
Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Calcium; Cardiomegaly; Disease Models, Animal; Echocardiography; Heart Fail | 1994 |
Functional beta-adrenoceptors in the left atrium of normotensive and hypertensive rats.
Topics: Animals; Atrial Function; Bisoprolol; Calcium Chloride; Ethanolamines; Heart Atria; Hypertension; Is | 1994 |
Cardiac beta-adrenoceptor-effector coupling in portal vein-stenosed rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Constriction; Cyclic | 1995 |
Regulation of the beta-adrenoceptor-cAMP-system during dynamic exercise in patients with primary hypertension after acute beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cyclic AMP; Exercise Test; Humans; Hyp | 1994 |
High calcium diet effectively opposes the development of deoxycorticosterone-salt hypertension in rats.
Topics: Acetylcholine; Animals; Blood Pressure; Calcium; Calcium, Dietary; Cardiomegaly; Desoxycorticosteron | 1994 |
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats.
Topics: Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Hypertension; In Vitro Techniques; Isoprote | 1994 |
Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension.
Topics: Adenylyl Cyclases; Adult; Blood Pressure; Case-Control Studies; Cholera Toxin; Colforsin; Cyclic AMP | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproter | 1994 |
[Pseudophaeochromocytoma (hypertensive crisis as a result of beta receptor hypersensitivity?)].
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Catecholamines; Drug Hypersensitivity; Humans; | 1993 |
Sensitivity to ischaemic ATP breakdown in different models of cardiac hypertrophy in rats.
Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Coronary Circulation; Hyperemia; Hypertension; Isopro | 1994 |
Decreased adrenergic response in hypertensive patients without left ventricular hypertrophy.
Topics: Adult; Analysis of Variance; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Hypertrop | 1994 |
Cardiovascular response and red cell membrane sodium transport in hypertensive cardiac hypertrophy.
Topics: Biological Transport; Blood Pressure; Cardiomegaly; Cardiovascular System; Erythrocyte Membrane; Fem | 1993 |
Guanine nucleotide regulatory protein alterations in young Milan hypertensive strain rats.
Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Colfor | 1994 |
Low ventricular performance and high resistance in established hypertension in adults.
Topics: Adult; Female; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Phentolamine; Receptors, Adre | 1993 |
Sex hormones change adrenoceptors in blood vessels of the spontaneously hypertensive rat.
Topics: Animals; Arteries; Blood Pressure; Dihydroalprenolol; Hypertension; Isoproterenol; Kinetics; Male; N | 1993 |
Observations on atrial natriuretic peptide, sympathetic activity and renal Ca2+ pump in diabetic and hypertensive rats.
Topics: Animals; Aorta, Abdominal; Atrial Natriuretic Factor; Blood Glucose; Ca(2+) Mg(2+)-ATPase; Calcium-T | 1993 |
Responsiveness to alpha- and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men.
Topics: Adolescent; Adult; Black People; Blood Pressure; Case-Control Studies; Humans; Hypertension; Isoprot | 1993 |
Decreased inotropic response to beta-adrenergic stimulation and normal sarcoplasmic reticulum calcium stores in the spontaneously hypertensive rat heart.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Calcium; Cell Compartmentation; Cryoultramicr | 1995 |
Loss of maximum attenuation and receptor reserve for isoprenaline at the beta 2-adrenoceptors of the portal veins of hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Hypertension; Hypertroph | 1995 |
Effects of long-term treatment with angiotensin-converting enzyme inhibitor on angiotensin II and prostacyclin release from mesenteric arteries in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Ca | 1995 |
Contractile function of cardiomyocytes from the spontaneously hypertensive rat.
Topics: Animals; Calcium; Cells, Cultured; Hypertension; Isoproterenol; Male; Myocardial Contraction; Rats; | 1996 |
Characterization of endothelium-dependent vasodilation and vasoconstriction in coronary arteries from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Coronary Vessels; Endothelium, Vascular; Heart R | 1996 |
Inhibition by cyclic AMP of basal and induced inositol phosphate production in cultured aortic smooth muscle cells from Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Animals; Cells, Cultured; Cyclic AMP; Hypertension; Inositol Phosphates; Isoproterenol; Male; Muscle | 1996 |
Beta-adrenoceptor responsiveness of splenic macrophages in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Catecholamines; Hypertension; Isoproterenol; Macrophages; Male; Phenylephri | 1996 |
Occurrence and properties of the hyperpolarization-activated current If in ventricular myocytes from normotensive and hypertensive rats during aging.
Topics: Aging; Animals; Cardiomegaly; Electric Conductivity; Electrophysiology; Hypertension; Isoproterenol; | 1996 |
The inhibitory effect of angiotensin II on stimulus-induced release of cAMP is augmented in the genetically hypertensive rat kidney.
Topics: Angiotensin II; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Hypertension; Isoproterenol; | 1996 |
Induction of cardiac angiotensinogen mRNA and angiotensin converting enzyme (ACE) activity in isoproterenol-induced heart injury.
Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Body Weight; Car | 1996 |
Renin secretion in conscious Lyon hypertensive rats.
Topics: Adrenergic beta-Agonists; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Antihypertensive | 1996 |
Influence of adrenodemedullation on beta 2- and beta 3-adrenoceptors mediating relaxation of oesophageal smooth muscle of spontaneously hypertensive rats.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Esop | 1996 |
Ramipril therapy improves arterial dilation in experimental hypertension.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclooxygenase Inhibitors; Diclofe | 1997 |
Restriction of nitric oxide rather than elevated blood pressure is responsible for alterations of vascular responses in nitric oxide-deficient hypertension.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Aorta; Cyclooxygenase I | 1996 |
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Chan | 1997 |
Sympathetic modulation of the effect of nifedipine on myocardial contraction and Ca current in the rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium Channel Blockers; | 1997 |
The effects of bromoacetylalprenololmenthane on the responses to isoprenaline of the left ventricle from normo-, prehyper- and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Res | 1997 |
Clonidine antagonizes pressor effect of N-methyl-D-aspartate in the rostral ventrolateral medulla of rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Clonidine; Dose-Respon | 1997 |
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1997 |
Antihypertensive effects of food-intake restriction in aortic coarctation hypertension.
Topics: Animals; Aortic Coarctation; Blood Pressure; Body Weight; Diet, Reducing; Female; Heart Rate; Hypert | 1997 |
Reduced vascular beta-adrenergic receptors and catecholamine response in rats with lead induced hypertension.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Catecholamines; Cyclic AMP; Epinephrine; Hypertension; In | 1997 |
Reduced inhibitory actions of adenosine A1 and kappa 1-opioid receptor agonists on beta-adrenoceptors in spontaneously hypertensive rat heart.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 1997 |
Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilation in patients with essential hypertension.
Topics: Acetylcholine; Adrenergic beta-Agonists; Case-Control Studies; Endothelium, Vascular; Female; Humans | 1998 |
Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Female; Heart; Heart Atr | 1998 |
Hostility and adrenergic receptor responsiveness: evidence of reduced beta-receptor responsiveness in high hostile men.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Heart Rate; Hostility; Human | 1998 |
Altered calcium handling in compensated hypertrophied rat cardiomyocytes induced by pressure overload.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiomegaly; Cells, Cultured; Colforsin; Heart; Hemodyn | 1998 |
Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Abdominal; Cardiomegaly; Cardiotonic Agents; Heart Ventric | 1998 |
Influence of gender on control of arterial tone in experimental hypertension.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Apamin; Blood Pressure; Cal | 1998 |
Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve.
Topics: Adrenergic beta-Agonists; Animals; Aortic Valve Stenosis; Arginine; Blood Pressure; Calcium; Case-Co | 1998 |
Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding.
Topics: Animals; Cells, Cultured; Colforsin; Hypertension; Isoproterenol; Nerve Growth Factors; Neuronal Pla | 1998 |
Modulation by angiotensin II of isoproterenol-induced cAMP production in preglomerular microvascular smooth muscle cells from normotensive and genetically hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calmodulin; Cyclic AMP; GTP-Binding Proteins; Hypertension; Isopro | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Fact | 1998 |
The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.
Topics: Aging; Animals; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Mode | 1999 |
Decreased beta2 adrenergic mediated venodilatation in Native Americans.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Female; Hand; Humans; Hypertension; Indi | 1998 |
Sympathetic and respiratory responses to hypoxia in essential hypertension.
Topics: Adrenergic beta-Agonists; Adult; Cyclic AMP; Female; Humans; Hypertension; Hypoxia; Isoproterenol; L | 1999 |
Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice.
Topics: Anesthesia; Animals; Atrial Function, Right; Blood Pressure; Cardiotonic Agents; Central Nervous Sys | 1999 |
Targeted disruption of the beta2 adrenergic receptor gene.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Energy Metabolism; Epinephrine; Gen | 1999 |
Modulation of the pacemaker current If by beta-adrenoceptor subtypes in ventricular myocytes isolated from hypertensive and normotensive rats.
Topics: Action Potentials; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antag | 1999 |
Changes of cardiac calcium homeostasis in spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1999 |
Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cromakalim; Cyclooxygenase Inhibitors; Di | 1999 |
G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Aorta; beta-Adrenergic Receptor Kinases; Cycli | 2000 |
Beta-adrenergic receptor density and function in left ventricular hypertrophy in young essential hypertensives.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Catecholamines; Cyclic AMP; Echocardiography; Femal | 2000 |
Postural hypotension following N-type Ca2+ channel blockade is amplified in experimental hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium Channel Blocke | 2000 |
Association analysis of beta2 adrenoceptor polymorphisms with hypertension in a Black African population.
Topics: Adrenergic beta-Agonists; Adult; Base Sequence; Black People; Case-Control Studies; DNA Primers; Fem | 2000 |
Contribution of cardiovascular hypersensitivity to orthostatic hypertension and the extreme dipper phenomenon.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aged; Antihypertensive Agents; Blood Pressure; | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; | 2000 |
Potassium augments vascular relaxation mediated by nitric oxide in the carotid arteries of hypertensive Dahl rats.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Carotid Arteries; Colforsin | 2000 |
[A comparative study of cardiac function in transgenic hypertensive rats, in spontaneously hypertensive rats and in normotensive rats].
Topics: Adrenergic beta-Agonists; Angiotensinogen; Animals; Animals, Genetically Modified; Atrial Natriureti | 2000 |
Impaired beta-adrenergic hyperpolarization in arteries from prehypertensive spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Cholera Toxin; Colforsin; Cromakalim; Hypertension; Isoproterenol; | 2001 |
The effects of hypoxia and sleep apnea on isoproterenol sensitivity.
Topics: Adrenergic beta-Agonists; Adult; Cross-Sectional Studies; Electroencephalography; Electromyography; | 1998 |
Measurement of cardiac function in conscious rats.
Topics: Analysis of Variance; Anesthetics, Inhalation; Animals; Aorta; Blood Flow Velocity; Blood Pressure; | 2001 |
Relevance of endothelium-derived hyperpolarizing factor in the effects of hypertension on rat coronary relaxations.
Topics: Acetylcholine; Animals; Biological Factors; Coronary Vessels; Dose-Response Relationship, Drug; Enzy | 2001 |
Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats.
Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Drug Synergism; Free Radical Scavengers; Glutathione; | 2001 |
Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension.
Topics: Adrenergic beta-Agonists; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; C | 2001 |
Enhanced protein phosphorylation in hypertensive hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Calcium-Binding Proteins; Calmodulin; Cardiomegaly; Hypertension; | 2001 |
Peripheral blood mononuclear cell CD62L and CD11a expression and soluble interstitial cell adhesion molecule-1 levels following infused isoproterenol in hypertension.
Topics: Adrenergic beta-Agonists; Blood Pressure; Body Mass Index; Dose-Response Relationship, Drug; Female; | 2002 |
Mechanical alternans and restitution in failing SHHF rat left ventricles.
Topics: Action Potentials; Animals; Calcium; Heart Failure; Heart Rate; Hypertension; Isoproterenol; Male; R | 2002 |
Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats.
Topics: Adrenergic beta-Agonists; Algorithms; Alprenolol; Animals; Aorta, Thoracic; Binding, Competitive; Bl | 2002 |
Autonomic control of cardiovascular functions during neonatal development and in adult sheep.
Topics: Acetylcholine; Animals; Animals, Newborn; Arrhythmias, Cardiac; Atropine; Autonomic Nerve Block; Aut | 1977 |
Catecholamines, cyclic AMP and renin in two contrasting forms of essential hypertension.
Topics: Adrenergic beta-Antagonists; Catecholamines; Cyclic AMP; Furosemide; Humans; Hypertension; Isoproter | 1977 |
[Effects of a beta-adrenolytic and a diuretic vis-à-vis hyper-reninemia induced by isoprenaline in anesthetized dogs. Value of beta blocking-diuretic interaction].
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Dogs; Humans; Hypertension; Isoproterenol; Renin; | 1977 |
[Action of 3-beta adrenolytics on plasma renin activity measured by radioimmunology in genetically hypertensive rats].
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Humans; Hypertension; Isoproterenol; Pindolol; Pr | 1977 |
Antihypertensive and beta-adrenoceptor antagonist action of timolol.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Heart Rate; Humans; Hypertension; Isopr | 1978 |
[Tetrapolar rheography in the study of pharmacodynamics of cardiotonic agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Glucagon; Heart Diseases; Humans; Hypertension; Isoprotere | 1978 |
The relationships between the cardiovascular effects, alpha- and beta-adrenoceptor blocking actions and plasma concentration of labetalol in doca hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chem | 1979 |
Interdose control of beta-blockade and arterial blood pressure during chronic oral labetalol treatment.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Drug Administration Schedule; Ethanolamines; Hea | 1979 |
SK&F 92657, a novel antihypertensive acting by precapillary vasodilatation and beta-adrenoreceptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Arteries; Blood Pressure; Cats; Guinea Pigs; Heart Atria; Hear | 1979 |
Inactive renin in human plasma.
Topics: Adult; Diazoxide; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Tech | 1976 |
Vascular responsiveness to norepinephrine, serotonin, and potassium chloride in veins from spontaneously hypertensive and age-matched Wistar Kyoto rats.
Topics: Animals; Aorta; Hypertension; In Vitro Techniques; Isoproterenol; Jugular Veins; Male; Nitroglycerin | 1979 |
Echocardiographic determination of left ventricular stress-velocity relations.
Topics: Adolescent; Adult; Aged; Angiocardiography; Aortic Valve Insufficiency; Aortic Valve Stenosis; Cardi | 1975 |
Changes in taurine concentration in heart and skeletal muscle during atrophy and hypertrophy.
Topics: Amino Acids; Animals; Atrophy; Cardiomegaly; Hypertension; Hypertrophy; Isoproterenol; Male; Muscle | 1975 |
Role of hypertension in ischemic heart disease and cerebral vascular disease in the cynomolgus monkey with coarctation of the aorta.
Topics: Animals; Aortic Coarctation; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Cerebral Arterie | 1977 |
[Immediate effects of desoxycorticosterone of vasomotor properties of noradrenaline and isoprenaline in rats].
Topics: Animals; Carotid Arteries; Desoxycorticosterone; Female; Hypertension; Isoproterenol; Jugular Veins; | 1978 |
Cyclic adenosine monophosphate and vascular reactivity in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta; Blood Vessels; Bucladesine; Cyclic AMP; Hypertension; Isoproteren | 1975 |
Cyclic AMP metabolism in the cardiac tissue of the spontaneously hypertensive rat.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Crosses, Genetic; Cyclic AMP; Disea | 1976 |
Plasma cyclic adenosine 3':5'-monophosphate response to isoproterenol and glucagon in hyperkinetic borderline (labile) hypertension.
Topics: Adult; Blood Pressure; Cyclic AMP; Female; Glucagon; Heart; Heart Rate; Hemodynamics; Humans; Hypert | 1976 |
Changes in some metabolic effects of isoprenaline and glucagon in normotensive and spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Enzyme Activation; Female; Glucagon; Heart Rate; Hypertensio | 1976 |
Plasma noradrenaline and adrenaline and beta-adrenoreceptor responsiveness in renin subgroups of essential hypertension.
Topics: Adult; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Male; M | 1978 |
Decreased number of beta-adrenergic receptors in hypertensive vessels.
Topics: Alprenolol; Animals; Binding Sites; Binding, Competitive; Blood Vessels; Cell Membrane; Hypertension | 1979 |
[Central cardiovascular effect of isoprenaline and some adrenergic beta blocking agents in neurogenic hypertensive dog: role of central beta-adrenoceptors (author's transl)].
Topics: Animals; Blood Pressure; Dogs; Female; Heart Rate; Hypertension; Isoproterenol; Male; Propranolol; R | 1978 |
Peripheral beta-receptor responsiveness in patients with essential hypertension.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Furosemide; Humans; Hydrochlorothia | 1979 |
Haemodynamics of ACTH-induced hypertension in sheep.
Topics: Acebutolol; Adrenocorticotropic Hormone; Animals; Blood Pressure; Cardiac Output; Disease Models, An | 1979 |
Predictive value of various parameters for the antihypertensive effect of the beta blocker ICI 66,082 (1).
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Catecholamine | 1975 |
A potentially antianginal benzo [b]thiophene with an amiodarone-like haemodynamic profile.
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Animals; Benzofurans; Blood Pressure; Card | 1975 |
Isoprenaline-induced myocardial infarction in spontaneously hypertensive rats.
Topics: Animals; Heart Failure; Hypertension; Isoproterenol; Liver; Male; Myocardial Infarction; Myocardium; | 1979 |
Diminished adenylate cyclase responses in frontal cortex and cerebral capillaries of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Albuterol; Animals; Capillaries; Cerebral Cortex; Cerebrovascular Circulation; Do | 1979 |
Low responsiveness of cardiac adenylate cyclase activity to peptide hormones in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Fluorides; Glucagon; Guanylyl Imidodip | 1979 |
Myocardial infarction in spontaneously hypertensive rats with superimposed adrenal-regeneration hypertension.
Topics: Adrenal Glands; Animals; Blood Urea Nitrogen; Body Weight; Corticosterone; Enzymes; Female; Hyperten | 1979 |
The effects of catecholamines on the smooth muscle cell membrane of the rat portal vein in various ionic solutions.
Topics: Animals; Anions; Catecholamines; Cations; Cell Membrane; Hypertension; In Vitro Techniques; Isoprote | 1979 |
Isoproterenol-evoked renin release from the in situ perfused kidney. Dose-response characteristics in spontaneously hypertensive and normotensive Wistar Rats.
Topics: Animals; Dose-Response Relationship, Drug; Hypertension; Isoproterenol; Kidney; Male; Perfusion; Pre | 1978 |
The determinants of plasma-renin activity in essential hypertension.
Topics: Adolescent; Adult; Humans; Hypertension; Isoproterenol; Kidney; Kidney Tubules, Distal; Male; Middle | 1978 |
Adentylate cyclase activity in myocardium of spontaneously hypertensive rat: effect of endogenous factors and solubilization.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cytosol; Detergents; Enzyme Activation; Glucagon; Hyperte | 1978 |
The effects of vasodilators in the perfused hind limbs of spontaneously hypertensive and normotensive rats.
Topics: Animals; Drug Interactions; Female; Hindlimb; Hypertension; In Vitro Techniques; Isoproterenol; Nitr | 1978 |
Altered function of adenylate cyclase in the myocardium of the spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Animals; Calcium; Guanylyl Imidodiphosphate; Hypertension; In Vitro Techniques; I | 1978 |
Characteristics of altered oxygen utilization in spontaneously hypertensive rats.
Topics: Animals; Hypertension; Isoproterenol; Lipid Metabolism; Male; Microsomes, Liver; Oxidoreductases, O- | 1978 |
Electrical property and chemical sensitivity of vascular smooth muscles in normotensive and spontaneously hypersensitive rats.
Topics: Action Potentials; Animals; Female; Hypertension; In Vitro Techniques; Isoproterenol; Male; Membrane | 1978 |
Influence of ageing on the isoprenaline relaxation of aortae from normal and hypertensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; M | 1978 |
Chronic antihypertensive drug treatment in young spontaneously hypertensive rats: Effects on arterial blood pressure, cardiovascular reactivity and vascular design.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Heart Rate; Hemodynamics; H | 1978 |
Role of the thyroid gland in the development and maintenance of spontaneous hypertension in rats.
Topics: Age Factors; Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Heart Rate; Hyp | 1977 |
Clinical evaluation of myocardial contractility and its problems.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Humans; Hypertension; Isoproterenol; Myoc | 1977 |
[Injectable verapamil as an arterial hypotensive drug--experimental study].
Topics: Animals; Dogs; Hypertension; Isoproterenol; Myocardial Contraction; Verapamil | 1977 |
Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. II. Relationship to its effect on blood pressure and plasma renin activity.
Topics: Adult; Alprenolol; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hyp | 1976 |
Left ventricular function during acute elevation of aortic blood pressure in dogs.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Volume; Cardiac Output; Constriction; Constric | 1976 |
Changes in some metabolic effects of isoprenaline and glucagon in normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Female; Glucagon; Hypertension; Isoproterenol; Male; Myocardium; Rats | 1976 |
Isoprotenerol induction of pineal serotonin N-acetyltransferase in normotensive and spontaneously hypertensive rats.
Topics: Acetyltransferases; Animals; Blood Pressure; Enzyme Induction; Female; Hypertension; Isoproterenol; | 1975 |
Brain amines and models of experimental hypertension.
Topics: Animals; Blood Pressure; Brain Stem; Cerebral Ventricles; Corticosterone; Disease Models, Animal; Do | 1975 |
Effect of isoproterenol on the blood vessels of the spontaneously hypertensive rat.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Hypertension; Isoproterenol; Microcirculation; | 1975 |
Hyperkinetic heart in severe hypertension: a separate clinical hemodynamic entity.
Topics: Adult; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Blood Volume; Cardiac Output; | 1975 |
Isoproterenol aerosols.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Blood Pressure; Electrocardiography; Female; Forced Expir | 1975 |
Altered cardiac responsiveness and regulation in the normal cardiac output type of borderlind hlpertension.
Topics: Adult; Atropine; Autonomic Nervous System; Blood Pressure Determination; Blood Volume Determination; | 1975 |
On the clinical value of calibrated displacement apexcardiography.
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Aortic Valve Stenosis; Blood Pressure; Coronary Disea | 1975 |
Isoprenaline-induced cardiac necroses in normotensive and in spontaneously hypertensive rats.
Topics: Animals; Disease Models, Animal; Electrocardiography; Female; Heart Diseases; Hypertension; Isoprote | 1975 |
Evaluation of myocardial contractility by the non-invasive method.
Topics: Aged; Atrial Fibrillation; Blood Pressure; Cardiac Output; Depression, Chemical; Digitalis Glycoside | 1975 |
Isoproterenol sensitivity and total body clearance of propranolol in hypertensive patients.
Topics: Adult; Age Factors; Blood Pressure; Body Weight; Heart Rate; Humans; Hypertension; Isoproterenol; Ma | 1976 |
Relaxant response of isolated basilar arteries to calcitonin gene-related peptide in stroke-prone spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Bucladesine; Calcitonin Gene-Re | 1992 |
Mitochondrial ATP synthase regulation in heart: defects in hypertension are restored after treatment with captopril.
Topics: Animals; Captopril; Cardiotonic Agents; Cells, Cultured; Electric Stimulation; Hypertension; Isoprot | 1992 |
Enhanced myocardial adenylate cyclase activity in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Catecholamines; Heart Rate; Hypertension; In Vitro Techni | 1992 |
The cardiac functional reserve in elderly hypertensive patients with abnormal diurnal change in blood pressure.
Topics: Aged; Blood Pressure; Cardiac Output; Circadian Rhythm; Echocardiography; Exercise; Female; Humans; | 1992 |
Regulation of the lymphocyte adenylate cyclase system by prostaglandin E2 infusions in resistant hypertensive subjects.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adult; Chromatography, High Pressure Liquid; Dinoprostone | 1992 |
Alteration of beta-adrenoceptor function in hypertensive patients with different degrees of left ventricular hypertrophy.
Topics: Adult; Blood Pressure; Cardiomegaly; Colforsin; Humans; Hypertension; Isoproterenol; Lymphocytes; Ma | 1992 |
beta-Adrenoceptor modulation of renin response to short-term reductions in pressure in young SHR.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Hypertension; Isoproterenol; Propranolol; Rats; Rats, | 1992 |
Kallikrein-kinin,enkephalin, renin-aldosterone and catecholamine systems in the vanadate (as vanadyl)-induced arterial hypertension.
Topics: Aldosterone; Animals; Blood Pressure; Bradykinin; Bucladesine; Catecholamines; Diastole; Enkephalins | 1992 |
Role of altered G-protein expression in the regulation of myocardial adenylate cyclase activity and force of contraction in spontaneous hypertensive cardiomyopathy in rats.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Cardiomegaly; Cell Membrane; GTP-Bin | 1992 |
Vascular beta-adrenoceptor-mediated responses in hypertension and ageing in rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Male; Muscle Contracti | 1992 |
Vascular tissue renin-angiotensin system in hypertensive humans.
Topics: Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Coronary Vessels; Forearm; Huma | 1992 |
Activation of beta 2-adrenoceptors by isoprenaline and adrenaline enhances noradrenaline release in cortical kidney slices of young spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Antagonists; Animals; Electric Stimulation; | 1992 |
Labored breathing in an elderly woman with hypertension.
Topics: Aged; Aged, 80 and over; Bradycardia; Cardiac Complexes, Premature; Dyspnea; Electrocardiography; Fe | 1992 |
Relationship between the sympatholytic action of nebivolol and hypotension.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Dose-Res | 1992 |
[Changes in heart genome expression in hypertensive diseases].
Topics: Animals; Contractile Proteins; Fibronectins; Gene Expression; Genome; Hypertension; In Situ Hybridiz | 1992 |
[Cardiac performance in elderly hypertensives with left ventricular hypertrophy].
Topics: Aged; Aged, 80 and over; Cardiomegaly; Echocardiography; Exercise Test; Female; Heart; Humans; Hyper | 1992 |
Pressure independence of renin release by isolated kidneys of Lyon hypertensive rats.
Topics: Animals; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; Kidney; Male; Perfusion; | 1992 |
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do | 1991 |
Blood pressure maintenance in hypertensive sympathectomized rats. I. Adrenal medullary catecholamines.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; | 1991 |
Left ventricular function in dogs 1 year after coarctectomy.
Topics: Animals; Aortic Coarctation; Dextrans; Disease Models, Animal; Dogs; Exercise Test; Heart Ventricles | 1991 |
Cardiac performance in elderly hypertensive patients with left ventricular hypertrophy: responses to isometric exercise and beta-agonists.
Topics: Aged; Blood Pressure; Cardiomegaly; Echocardiography; Exercise; Heart Rate; Humans; Hypertension; Is | 1991 |
Active and inactive renin in human forearm of hypertensive patients.
Topics: Female; Forearm; Humans; Hypertension; Isoproterenol; Male; Regional Blood Flow; Renin | 1991 |
Clinical aspects on presynaptic noradrenaline metabolism.
Topics: Chromatography, High Pressure Liquid; Desipramine; Humans; Hypertension; Isoproterenol; Methoxyhydro | 1991 |
[Hypertrophic cardiomyopathy with left ventricular dynamic obstruction syndrome in hypertensive adult patients].
Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Echocardiography; Humans; Hypertension; Isoproterenol; Mi | 1991 |
Ontogeny of renal renin release in spontaneously hypertensive rat and Wistar-Kyoto rat.
Topics: Aging; Angiotensin II; Animals; Hypertension; Isoproterenol; Kidney Cortex; Kidney Tubules, Proximal | 1991 |
Pharmacological characteristics of the stereoisomers of carvedilol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; | 1990 |
Validation of non-invasive measurement of cardiac output. The Ann Arbor experience.
Topics: Carbon Dioxide; Cardiac Output; Echocardiography; Echocardiography, Doppler; Heart Rate; Humans; Hyp | 1990 |
Is hypertension during CPB harmful?
Topics: Blood Pressure; Cardiopulmonary Bypass; Humans; Hypertension; Isoproterenol; Norepinephrine; Phenyle | 1990 |
Isoproterenol and myocardial O2 supply/consumption in hypertension-induced myocardial hypertrophy.
Topics: Animals; Biological Availability; Cardiac Output; Cardiomegaly; Coronary Circulation; Endocardium; H | 1990 |
Left ventricular reserve of the hypertrophied heart in patients with systemic hypertension and hypertrophic cardiomyopathy--relation to age and left ventricular relative wall thickness.
Topics: Adolescent; Adult; Age Factors; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female | 1990 |
Isolated myocardial cells: a new tool for the investigation of hypertensive heart disease.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Heart Rate; Hypertension; Isoproterenol; Myo | 1990 |
Diastolic properties of hypertrophied hearts in essential hypertension: classification by left ventricular wall stress.
Topics: Adult; Cardiomegaly; Diastole; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Isoprot | 1990 |
Defective venous beta-adrenergic response in borderline hypertensive subjects is corrected by a low sodium diet.
Topics: Adult; Blood Pressure; Catecholamines; Diet, Sodium-Restricted; Electrolytes; Humans; Hypertension; | 1990 |
Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro.
Topics: Adult; Arteries; Diet, Sodium-Restricted; Epinephrine; Humans; Hypertension; Infusions, Intravenous; | 1990 |
Renovascular beta adrenergic hypersensitivity and hyperinsulinemia in rats with dietary-induced obesity.
Topics: Angiotensins; Animals; Blood Pressure; Dietary Fats; Hypertension; Insulin; Isoproterenol; Male; Obe | 1990 |
Mechanical and non-mechanical factors in hypertensive hypertrophy, their clinical roles.
Topics: Biomechanical Phenomena; Blood Pressure; Cardiomegaly; Humans; Hypertension; Isoproterenol; Myocardi | 1990 |
Vascular flow capacity of hindlimb skeletal muscles in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Capillary Permeability; Hindlimb; Humans; Hypertension; Isoproterenol; Musc | 1990 |
Adenylate cyclase activities of vascular smooth muscle in early and established DOCA/salt hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calmodulin; Colforsin; Desoxycorticosterone; Guanosine | 1990 |
Increased beta-adrenoceptor binding capacity is associated with blunted beta-adrenoceptor-mediated cardiovascular responses in essential hypertension.
Topics: Adult; Catecholamines; Dihydroalprenolol; Humans; Hypertension; Isoproterenol; Leukocytes; Middle Ag | 1985 |
Cardiovascular adrenoreceptor number and function in experimental hypertension in the baboon.
Topics: Animals; Disease Models, Animal; Hemodynamics; Hypertension; Isoproterenol; Muscle, Smooth, Vascular | 1985 |
Study of the pathogenesis of cardiac hypertrophy--biochemical differences of cultured heart cells from normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Hypertension; Isoproterenol; Leucine; Myocar | 1989 |
beta-adrenergic reactivity in conscious DOCA-salt hypertensive rats.
Topics: Animals; Desoxycorticosterone; Endocrine Glands; Hemodynamics; Hypertension; Insulin; Isoproterenol; | 1989 |
Regulation of Na+ and K+ contents in rat thymocytes.
Topics: Animals; Biological Transport; Blood Coagulation Factors; Bumetanide; Dinoprostone; Hypertension; Is | 1989 |
Autonomic receptor interactions in isolated cardiac myocytes from hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Blood Pressure; Carbachol; Guanosine Triphosphate; Hypertension; In Vitr | 1989 |
Supersensitivity of beta-adrenoceptor coupled adenylate cyclase in pulmonary tissue of the spontaneously hypertensive rat.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Guanylyl Imidodiphosphate; Hyper | 1989 |
Beta-adrenergic receptor differences in cultured arterial smooth muscle cells between spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Animals; Cells, Cultured; Cyclic AMP; Hypertension; Isoproterenol; Kinetics; Male; Muscle, Smooth, V | 1989 |
Antihypertensive contribution of sodium depletion and the sympathetic axis during chronic angiotensin II converting enzyme inhibition.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiovascular Physiological Phenomena; Diet, Sodium-Re | 1989 |
Enhanced presynaptic facilitation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Captopril; Female; Hypertensio | 1989 |
Intracellular distribution of cardiac beta-adrenoceptors in SHR and WKY.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Heart; Hypertension; In Vitro Techni | 1989 |
Effects of dilevalol on forearm circulation in essential hypertension.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Female; Forearm; Hemodynamics; Humans; | 1989 |
Hyperkinetic hemodynamic pattern in some borderline hypertension: differential responses to alpha and beta agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adult; Blood Pressure; Cardiac Output; Diastole | 1989 |
Hemodynamic and beta-adrenergic receptor adaptations during long-term beta-adrenoceptor blockade. Studies with acebutolol, atenolol, pindolol, and propranolol in hypertensive patients.
Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Adult; Aldosterone; Catecholamines; Hemodyna | 1989 |
Adrenergic regulation of calcium-deficient hypertension in chick embryos.
Topics: Animals; Blood Pressure; Calcium; Chick Embryo; Diastole; Dopamine; Epinephrine; Hypertension; Isopr | 1989 |
Enhanced formation of lipid peroxides might contribute to the high sensitivity of spontaneously hypertensive rats towards isoproterenol-induced myocardial damage.
Topics: Animals; Aspartate Aminotransferases; Body Weight; Cardiomyopathies; Coronary Disease; Creatine Kina | 1989 |
Development of hypertension in rats during chronic exposure to cold.
Topics: Acclimatization; Animals; Blood Pressure; Cold Temperature; Heart Rate; Hypertension; Isoproterenol; | 1989 |
Cardiovascular regulatory functions in elderly patients with hypertension.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Cardiovascular System; Female; Heart; H | 1989 |
Sympathetic nervous function and erythrocyte cation transport systems in normotensive individuals with family history of hypertension.
Topics: Adult; Biological Transport; Blood Pressure; Cardiac Output; Cations, Monovalent; Erythrocytes; Hear | 1989 |
Cadmium-induced hypertension in rats.
Topics: Acetylcholine; Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Body Weight; Cadmium; Calcium | 1989 |
Altered vascular beta adrenoceptor-mediated relaxation in deoxycorticosterone-salt hypertensive rats.
Topics: Animals; Atenolol; Bucladesine; Butoxamine; Desoxycorticosterone; Fenoterol; Hypertension; Isoproter | 1988 |
Glandular adenylate cyclase system in genetic hypertension: age-dependent response to catecholamines.
Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Fluorides; Hyperten | 1988 |
Impaired desensitization of cardiac beta-adrenoceptors in the spontaneously hypertensive rat.
Topics: Animals; Cell-Free System; Heart; Hypertension; Isoproterenol; Myocardium; Protein Kinases; Rats; Ra | 1988 |
Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
Topics: Aging; Animals; Cardiomegaly; Electric Stimulation; Hypertension; In Vitro Techniques; Isoproterenol | 1988 |
Acute regulation of lymphocyte beta 2-adrenoceptors is altered in patients with essential hypertension.
Topics: Adult; Blood Pressure; Cyclic AMP; Exercise; Humans; Hypertension; Iodocyanopindolol; Isoproterenol; | 1985 |
Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia; Blood Pressure; Dose-Response Relationship, Drug; Hea | 1985 |
Chronic salt loading and central adrenergic mechanisms in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Dopamine; Heart Rate; Hexamethonium; Hex | 1985 |
Bucindolol in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Creatine Kinase; Drug Administration Sched | 1985 |
Beta-adrenergic modulation of pulmonary transvascular fluid and protein exchange.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Body Fluids; Capillary Permeability; | 1986 |
Alpha 1-adrenergic blockade and cardiovascular pressor responses in essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Cardiovascular System; Drug Interactions; Elect | 1986 |
Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.
Topics: Acebutolol; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Blood Pressure; Decerebrate St | 1986 |
Study of prejunctional beta-adrenoceptors in kidneys of normotensive and hypertensive rats using the new beta-adrenoceptor blocking drug tertatolol.
Topics: Adrenergic beta-Antagonists; Animals; Hypertension; In Vitro Techniques; Isoproterenol; Kidney; Male | 1986 |
[Changes in the sensitivity of cardiovascular beta adrenergic receptors after sinoaortic denervation in rats].
Topics: Animals; Blood Pressure; Denervation; Female; Hexamethonium; Hexamethonium Compounds; Hypertension; | 1986 |
[Responses of hypertensive-hypertrophied ventricle to beta-adrenergic stimulation in man].
Topics: Adult; Cardiomegaly; Cardiomyopathy, Hypertrophic; Humans; Hypertension; Isoproterenol; Middle Aged; | 1985 |
[Left ventricular function in essential hypertension during isoproterenol infusion].
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Heart; Heart Rate; Humans; Hypertension | 1985 |
Cardiac function of patients with essential hypertension during exercise and isoproterenol infusion.
Topics: Adult; Aged; Cardiomegaly; Echocardiography; Electrocardiography; Exercise Test; Female; Hemodynamic | 1987 |
Classification of hypertrophied hearts in essential hypertension: evaluation by left ventricular wall stress and adrenergic responses.
Topics: Adult; Aged; Cardiomegaly; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Isoproteren | 1988 |
Role of cyclic AMP protein kinase in decreased arterial cyclic AMP responsiveness in hypertension.
Topics: Animals; Aorta, Thoracic; Arteries; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Hypertensi | 1985 |
[Sensitivity and response of beta 2-adrenergic receptors of isolated lymphocytes in essential hypertension].
Topics: Adult; Cyclic AMP; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Middle Aged; Receptors, A | 1985 |
Function of the autonomic nervous system in young, untreated hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Catecholamines; Exercise Test; Humans; Hypertension; Isoprote | 1986 |
Adrenergic activity and left ventricular function during treatment of essential hypertension with calcium antagonists.
Topics: Adult; Blood Pressure; Epinephrine; Female; Heart; Heart Rate; Humans; Hypertension; Isoproterenol; | 1986 |
[Interindividual changes in the specific binding of 3H-dihydroalprenolol by beta 2-adrenergic lymphocytic receptors in essential hypertension].
Topics: Adult; Alprenolol; Dihydroalprenolol; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Recept | 1986 |
Increased sensitivity to alpha-adrenoceptor stimulation but intact purinergic and muscarinergic effects in prehypertensive cardiac hypertrophy of spontaneously hypertensive rats.
Topics: Adenosine; Animals; Carbachol; Cardiomegaly; Hypertension; In Vitro Techniques; Isoproterenol; Male; | 1986 |
Enhanced lipolysis is not evident in adipocytes from exercise-trained SHR.
Topics: Adipose Tissue; Animals; Bucladesine; Cyclic AMP; Female; Glycerol; Hypertension; Isoproterenol; Kin | 1986 |
Physiologic responses to chronic dietary tyrosine supplementation in DOCA-salt-treated rats.
Topics: Animals; Catecholamines; Cerebral Cortex; Desoxycorticosterone; Hypertension; Isoproterenol; Male; N | 1986 |
Lipolysis and beta-adrenergic receptor binding on adipocytes of spontaneously hypertensive rats.
Topics: Adipose Tissue; Animals; Cyclic AMP; Dihydroalprenolol; Hypertension; Isoproterenol; Lipolysis; Rats | 1987 |
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guano | 1987 |
Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension.
Topics: Albuterol; Animals; Arteries; Dinoprost; Hydroxydopamines; Hypertension; Isoproterenol; Male; Nitrop | 1987 |
Dietary potassium, blood pressure and peripheral adrenergic responsiveness in the deoxycorticosterone acetate-salt rat.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Diet; Disease Models, Animal; Hypertension; Isoproter | 1988 |
Nonshivering thermogenesis and brown fat in spontaneously hypertensive rats.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Hypertension; Isoproterenol; Oxygen Con | 1988 |
[Water intake induced by isoprenaline in 2 models of experimental hypertension in rats].
Topics: Animals; Desoxycorticosterone; Drinking; Hypertension; Hypertension, Renovascular; Isoproterenol; Ma | 1987 |
Altered endothelial modulation of vascular tone in aging and hypertension.
Topics: Adenosine; Aging; Animals; Blood Vessels; Desoxycorticosterone; Dose-Response Relationship, Drug; En | 1987 |
Reactivity of aorta and mesenteric microvessels to drugs in spontaneously hypertensive rats: role of the endothelium.
Topics: Acetylcholine; Animals; Aorta; Aorta, Thoracic; Endothelium; Female; Hypertension; In Vitro Techniqu | 1987 |
Chronic dietary administration of tryptophan prevents the development of deoxycorticosterone acetate salt induced hypertension in rats.
Topics: Angiotensin II; Animals; Brain; Desoxycorticosterone; Diuresis; Drug Administration Schedule; Female | 1987 |
Extracellular calcium and altered vascular responsiveness in the deoxycorticosterone acetate-salt rat.
Topics: Animals; Calcium; Desoxycorticosterone; Dose-Response Relationship, Drug; Extracellular Space; Femor | 1986 |
The effect of propranolol on catecholamine clearance.
Topics: Blood Pressure; Drug Interactions; Half-Life; Humans; Hypertension; Isoproterenol; Norepinephrine; P | 1986 |
Differential effects of phentolamine on the responsiveness of aortic and femoral smooth muscle from normotensive and DOCA/NaCl hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Femoral Artery; Hypertension; In Vitro Techniques; Isoproteren | 1986 |
Cerebral vascular responsiveness in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Basilar Artery; Blood Pressure; Calcium; Cerebrovascular Circulation; Desoxycorticosterone; | 1987 |
Renin release from nonclipped kidneys of 2K-1C hypertensive rats.
Topics: Animals; Blood Pressure; Glomerular Filtration Rate; Hypertension; In Vitro Techniques; Isoprotereno | 1985 |
Angiotensin-induced hypertension in conscious dogs: biochemical parameters and baroreceptor reflex.
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Consciousness; Disease Models, Animal; Dogs; Fema | 1985 |
Enhanced renin secretion in adrenalectomized rats with glucocorticoid-induced hypertension.
Topics: Adrenalectomy; Animals; Blood Pressure; Heart Rate; Hypertension; Isoproterenol; Male; Methylprednis | 1985 |
Adrenergic-induced enhancement of brain barrier system permeability to small nonelectrolytes: choroid plexus versus cerebral capillaries.
Topics: Acetazolamide; Animals; Blood; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; C | 1985 |
Aromatic L-amino acid decarboxylase, dopamine beta-hydroxylase, monoamine oxidase, malondialdehyde, and acid phosphatase in rat brain capillaries and kidney glomeruli in experimental hypertension.
Topics: Acid Phosphatase; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Capillaries; Desoxycorticost | 1985 |
Cardiovascular effects of drugs acting on the autonomous nervous system, in awake, normotensive and hypertensive rats.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Blood Pressure; Epinephrine; Heart Rate; Hemodynam | 1985 |
Measurement of regional neuronal removal of norepinephrine in man.
Topics: Arm; Biological Transport; Desipramine; Humans; Hypertension; Isoproterenol; Kinetics; Metabolic Cle | 1985 |
Mechanism of elevation of hindquarter vascular resistance in spontaneously hypertensive rats.
Topics: Animals; Biomechanical Phenomena; Blood Pressure; Capillaries; Epinephrine; Ganglia; Hindlimb; Hyper | 1985 |
The effects of aerobic exercise on plasma catecholamines and blood pressure in patients with mild essential hypertension.
Topics: Adult; Blood Pressure; Epinephrine; Exercise Therapy; Heart Rate; Humans; Hypertension; Isoprotereno | 1985 |
Norepinephrine-related mechanism in hypertension accompanying renal failure.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Debrisoquin; Female; Heart Rate; Humans; | 1985 |
The effect of pharmacologically increased blood pressure on brain circulation. Angiographic investigation of arterial diameter and blood flow in patients with normal and pathological angiograms.
Topics: Absorptiometry, Photon; Anthropometry; Blood Pressure; Brain Injuries; Brain Neoplasms; Carotid Arte | 1973 |
Verapamil in cardiology.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmi | 1974 |
Effects of prolonged treatment with adrenergic beta-receptor antagonists on blood pressure, cardiovascular design and reactivity in spontaneously hypertensive rats (SHR).
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Di | 1974 |
Aberrations of cyclic nucleotide metabolism in the hearts and vessels of hypertensive rats.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Desoxycorticosterone; Guanylate | 1974 |
[Ventricular tachycardia with variable focus and dyskaliemia].
Topics: Aged; Alcoholism; Bradycardia; Cardiac Complexes, Premature; Electrocardiography; Female; Heart Bloc | 1969 |
A comparison of the effects of some inotropic and chronotropic agents on isolated atria from normotensive (NTR) and spontaneously hypertensive (SHR) rats.
Topics: Acetylcholine; Aminophylline; Animals; Blood Pressure; Body Weight; Depression, Chemical; Edetic Aci | 1974 |
Spurious heart disease in athletic children.
Topics: Adolescent; Blood Pressure; Bradycardia; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Diag | 1968 |
[On the importance of the formation of metabolites for the blood pressure-lowering effect of alpha-methyldopa].
Topics: Blood Pressure; Catecholamines; Hypertension; Isoproterenol; Methyldopa; Propranolol | 1967 |
Abnormal cardiac norepinephrine storage in isoproterenol-treated rats.
Topics: Animals; Cardiomegaly; Desoxycorticosterone; Heart; Hypertension; Hypotension; Isoproterenol; Male; | 1968 |
The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly.
Topics: Anemia, Hypochromic; Animals; Cardiomegaly; Collagen; Hydroxyproline; Hypertension; Hypertrophy; Hyp | 1969 |
Role of endocrine factors in the pathogenesis of cardiac hypertrophy.
Topics: Acromegaly; Animals; Body Weight; Cardiomegaly; Catecholamines; Disease Models, Animal; Growth Hormo | 1974 |
Development of modern components of the mechanism of cardiac hypertrophy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Cardiomyopathies; Cold Tempera | 1974 |
Changes in the carotid pulse which occur with age and hypertension.
Topics: Adult; Aging; Amyl Nitrite; Angiotensin II; Arteriosclerosis; Blood Pressure; Carotid Arteries; Elec | 1966 |
[Changes in the hypertensive effects of angiotensin by adrenergic and anti-adrenergic agents].
Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Bretylium Compounds; Cocaine; Desipramine; Dib | 1968 |
Drug-induced changes in blood pressure as recorded by direct and indirect methods.
Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Blood Pressure Determination; Dogs; Guanethidine; | 1969 |
"Non-pheochromocytoma".
Topics: Adrenal Gland Neoplasms; Adult; Arteriovenous Fistula; Asthma; Celiac Disease; Child, Preschool; Dia | 1970 |
Effect of upright posture and isoproterenol infusion on cyclic adenosine monophosphate excretion in control subjects and patients with labile hypertension.
Topics: Adult; Blood Pressure; Creatinine; Cyclic AMP; Female; Humans; Hypertension; Isoproterenol; Male; Ph | 1973 |
Isoproterenol and glucagon effects in perfused hearts from spontaneously hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Cyclic AMP; Glucagon; Glycerol; Glycogen; Heart; Hypertension; In Vitro Tec | 1973 |
Borderline hypertension: correlation between the cardiac output and the vascular reactivity to norepinephrine.
Topics: Adult; Angiotensin II; Cardiac Output; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Norepi | 1974 |
The treatment of hypertension by beta adrenergic blocking drugs.
Topics: Antihypertensive Agents; Ergot Alkaloids; Ethanolamines; Guanethidine; Humans; Hypertension; Isoprot | 1966 |
Isoetharine methanesulfonate with phenylephrine hydrochloride and thenyldiamine (Bronkometer) in hypertensive and sympathomimetic amine-sensitive asthmatic patients.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Blood Pressure Determination; Drug Hypersensitivity; Fema | 1967 |
[Experimental study of direct vascular activity of amitriptyline].
Topics: Amitriptyline; Animals; Blood Vessels; Central Nervous System Stimulants; Ethanolamines; Heart; Hype | 1967 |
[Influence of hypocapnic gaseous alkalosis on beta effects of sympathomimetics].
Topics: Acid-Base Equilibrium; Alkalosis; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Dogs; Ephedri | 1969 |
[Group discussion: progress in cardiopathology].
Topics: Adrenergic beta-Antagonists; Coronary Angiography; Coronary Vessels; Extracorporeal Circulation; Glu | 1971 |
Hyperdynamic circulation and hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Hyper | 1972 |
[What is assured in treatment with beta receptor blockaders?].
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Cresols; Heart Diseases; Huma | 1972 |
Electrical property of cardiac cell membrane of spontaneously hypertensive rat.
Topics: Acetylcholine; Action Potentials; Animals; Atrial Function; Cell Membrane; Depression, Chemical; Ele | 1974 |
The effect of prostaglandin E2 on the arterial blood pressure of normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, | 1974 |
Effects of a pressure load on left ventricular systolic time intervals.
Topics: Animals; Aorta; Blood Pressure; Cardiac Volume; Constriction; Dogs; Electrocardiography; Heart; Hear | 1973 |
Preload, contractility, and afterload as determinants of stroke volume during elevation of aortic blood pressure in dogs.
Topics: Animals; Aorta; Atropine; Blood Pressure; Cardiac Volume; Dextrans; Dogs; Heart; Heart Rate; Heart V | 1973 |
Addition of isoproterenol prevents adverse hemodynamic effects of vasopressin.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Drug Combin | 1973 |
Barium-induced skeletal muscle paralysis in the rat, and its relationship to human familial periodic paralysis.
Topics: Adrenal Glands; Animals; Arrhythmias, Cardiac; Barium; Calcium; Female; Hypertension; Hypokalemia; I | 1974 |
Adrenocortical changes associated with methylandrostenediol-induced hypertension and isoproterenol-induced myocardial infarction in arteriosclerotic versus nonarteriosclerotic rats.
Topics: Adrenal Glands; Anabolic Agents; Animals; Aorta; Arteriosclerosis; Cholesterol; Corticosterone; Fema | 1974 |
Hemodynamics of the spontaneously hypertensive rat: effects of isoproterenol.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Hypertension; Isoproteren | 1974 |
[Electrocardiographic changes and severe rhythm disorders during meningeal hemorrhages or after neurosurgical intervention].
Topics: Adult; Aneurysm; Basilar Artery; Bradycardia; Brain Neoplasms; Cerebral Arteries; Electric Countersh | 1974 |
Effect of practolol on blood pressure and renin release in man.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; I | 1974 |
[Light halothane anesthesia for pacemaker implantation (series of 200 cases)].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Child; Diabetes Complications; D | 1974 |
[Clinical and experimental studies on the immunologic aspects of myocardial infarct].
Topics: Agglutination Tests; Anemia; Angina Pectoris; Animals; Antibody Formation; Antigen-Antibody Reaction | 1970 |
[The 1st lead of the carotid sphygmogram in valvular and arterial heart diseases].
Topics: Adolescent; Adult; Aged; Amyl Nitrite; Aortic Valve Insufficiency; Aortic Valve Stenosis; Arterioscl | 1969 |
Clinical studies on apexcardiogram. II. Cardiac movement in thyroid dysfunction and coronary heart disease from the point of apexcardiogram.
Topics: Adolescent; Adult; Angina Pectoris; Arteriosclerosis; Coronary Disease; Electrocardiography; Female; | 1971 |
Electrocardiographic changes in anaphylactic shock of the rabbit.
Topics: Anaphylaxis; Animals; Blood Pressure; Electrocardiography; Epinephrine; Heart; Hypertension; Hypoten | 1972 |
Differences of cardiac reactivity between spontaneously hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Body Weight; Epinephrine; Heart Atria; Heart Rate; Hypertension; Isoprotere | 1972 |
Relation of propranolol plasma level to beta-blockade during oral therapy.
Topics: Administration, Oral; Heart Rate; Humans; Hypertension; Isoproterenol; Propranolol; Receptors, Adren | 1972 |
Effects of increased arterial pressure and positive inotropic agents on the severity of myocardial ischemia in the acutely depressed heart.
Topics: Animals; Arteries; Blood Pressure Determination; Coronary Disease; Digitalis Glycosides; Dogs; Heart | 1972 |
Hemodynamic studies on hypertension. II. Effects of isoproterenol, propranolol, noradrenaline and phentolamine on the hemodynamics in essential hypertension.
Topics: Adult; Blood Pressure; Cardiac Output; Depression, Chemical; Female; Heart Rate; Hemodynamics; Human | 1972 |
Role of parasympathetic inhibition in the hyperkinetic type of borderline hypertension.
Topics: Adolescent; Adult; Atropine; Blood Circulation; Blood Pressure; Cardiac Output; Heart Rate; Humans; | 1971 |
The pressure-flow relationship of the pulmonary circulation in normal man and in chronic obstructive pulmonary diseases. Effects of muscular exercise.
Topics: Airway Resistance; Angiography; Blood Pressure; Blood Viscosity; Blood Volume; Carbon Dioxide; Chrom | 1971 |
Vascular smooth muscle reactivity in normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Muscle Contraction; Muscle, S | 1969 |
[ Sensitivity of alpha- and betareceptors in patients with hypertension].
Topics: Blood Pressure; Cardiac Output; Chemoreceptor Cells; Drug Hypersensitivity; Heart Rate; Hemodynamics | 1970 |
Hyperdynamic beta-adrenergic circulatory state. An overview.
Topics: Blood Circulation; Body Weight; Heart Rate; Hypertension; Isoproterenol; Propranolol; Receptors, Dru | 1970 |
[Research on the sympathetic vascular innervation in animals with aortic coarctation. Different responses to norepinephrine and isoprenaline in the hypertensive segment and in the hypotensive segment. Preliminary note].
Topics: Animals; Aortic Coarctation; Blood Vessels; Dogs; Hypertension; Hypotension; Isoproterenol; Norepine | 1970 |
[Cardiac involvement in tetanus].
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Autopsy; Catecholamines; Child; Electrocardiography; | 1970 |
[Computation of mean arterial blood pressure].
Topics: Adolescent; Adult; Arteries; Blood Pressure; Blood Pressure Determination; Carotid Arteries; Female; | 1971 |
[Effect of sympathomimetics on the vasomotor centers].
Topics: Animals; Blood Pressure; Bradycardia; Cats; Hemodynamics; Hypertension; Hypotension; Isoproterenol; | 1971 |
A comparison of some cardiovascular properties of propranolol, MJ 1999 and quinidine in relation to their effects in hypertensive animals.
Topics: Anilides; Animals; Blood Pressure; Cardiovascular System; Dogs; Electrocardiography; Female; Heart R | 1968 |
Increases beta-receptor responsiveness; central or peripheral?
Topics: Autonomic Nervous System; Cardiovascular Diseases; Chemoreceptor Cells; Hypertension; Isoproterenol; | 1969 |
Hemodynamic effects of glucagon in patients with heart disease.
Topics: Blood Glucose; Blood Pressure; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Glucagon; | 1969 |
A chemically induced experimental ocular hypertension for evaluating drug effects in albino rabbits.
Topics: Animals; Carbachol; Epinephrine; Female; Formaldehyde; Glaucoma; Hypertension; Intraocular Pressure; | 1969 |
Interactions of sympathomimetic and sympatholytic agents in normotensive and hypertensive subjects.
Topics: Blood Pressure; Heart Rate; Humans; Hypertension; Injections, Intravenous; Isoproterenol; Norepineph | 1969 |
Shock and its management.
Topics: Anti-Bacterial Agents; Anticoagulants; Blood Cell Count; Blood Pressure; Blood Transfusion; Body Wei | 1969 |
Myocardial revascularization with internal mammary artery implantation: current status.
Topics: Aneurysm; Angina Pectoris; Angiography; Arteriosclerosis; Blood Flow Velocity; Collateral Circulatio | 1969 |
Peripheral arterial insufficiency. A complication of beta-adrenergic blocking therapy.
Topics: Adult; Blood Circulation; Cardiovascular Diseases; Female; Heart Diseases; Humans; Hypertension; Hys | 1969 |