baclofen has been researched along with Hypertension in 25 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries." | 7.74 | Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008) |
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 7.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| "Baclofen (20 mg/kg) was neuroprotective (potency ratio of 3." | 5.30 | High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. ( Jackson-Friedman, C; Jin, A; Lyden, PD; Nunez, S; Zweifler, R, 1997) |
| "Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries." | 3.74 | Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008) |
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 3.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| "The hypertension and tachycardia after intraperitoneal administration of baclofen, 5 mg kg-1, to conscious rats was prevented by a midcollicular decerebration but not by a brain transection rostral to the hypothalamus." | 3.66 | A hypertensive response to baclofen in the nucleus tractus solitarii in rats. ( Persson, B, 1981) |
| "To study the possible influence of sympathetic adrenergic tone on the blood-brain barrier function during acute hypertension in conscious unrestrained rats with indwelling catheters in the aorta and a jugular vein the blood pressure was increase by noradrenaline, 6-hydroxydopamine (6-OHDA) or baclofen." | 3.66 | Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats. ( Auer, LM; Johansson, BB, 1983) |
| "Baclofen per se has the potential of lowering blood pressure." | 1.35 | Intrathecal baclofen for autonomic instability due to spinal cord injury. ( Kofler, M; Poustka, K; Saltuari, L, 2009) |
| "Baclofen is a lipophilic analogue of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in central nervous system." | 1.33 | Selected clinical aspects of acute intoxication with baclofen. ( Burda, P; Chodorowski, Z; Sein Anand, J, 2005) |
| "There was no correlation between the dosage of baclofen and the clinical outcome." | 1.32 | [Acute intoxication with baclofen]. ( Chodorowski, Z; Sein Anand, J; Wiśniewski, M, 2004) |
| "Baclofen has both presynaptic and postsynaptic effects." | 1.31 | gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension. ( Mifflin, SW; Vitela, M, 2001) |
| "Baclofen (20 mg/kg) was neuroprotective (potency ratio of 3." | 1.30 | High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. ( Jackson-Friedman, C; Jin, A; Lyden, PD; Nunez, S; Zweifler, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (32.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 13 (52.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, DP | 2 |
| Yang, Q | 1 |
| Pan, HM | 1 |
| Pan, HL | 2 |
| Kofler, M | 1 |
| Poustka, K | 1 |
| Saltuari, L | 1 |
| Salazar, ML | 1 |
| Eiland, LS | 1 |
| Zhang, Q | 1 |
| Yao, F | 2 |
| O'Rourke, ST | 2 |
| Qian, SY | 1 |
| Sun, C | 2 |
| Zhang, W | 2 |
| Mifflin, S | 2 |
| Vorobyov, V | 1 |
| Schibaev, N | 1 |
| Kaptsov, V | 1 |
| Kovalev, G | 1 |
| Sengpiel, F | 1 |
| Bardutzky, J | 1 |
| Tronnier, V | 1 |
| Schwab, S | 1 |
| Meinck, HM | 1 |
| Dykewicz, MS | 1 |
| Chodorowski, Z | 2 |
| Sein Anand, J | 2 |
| Wiśniewski, M | 1 |
| Cheng, YW | 1 |
| Ku, MC | 1 |
| Ho, CM | 1 |
| Chai, CY | 1 |
| Su, CK | 1 |
| Burda, P | 1 |
| Herrera-Rosales, M | 1 |
| Sumners, C | 1 |
| Persson, B | 1 |
| Unger, T | 1 |
| Rockhold, RW | 1 |
| Yukimura, T | 1 |
| Rettig, R | 1 |
| Ganten, D | 1 |
| DeFeudis, FV | 1 |
| Johansson, BB | 1 |
| Auer, LM | 1 |
| Jackson-Friedman, C | 1 |
| Lyden, PD | 1 |
| Nunez, S | 1 |
| Jin, A | 1 |
| Zweifler, R | 1 |
| Ichida, T | 1 |
| Kuriyama, K | 1 |
| Vitela, M | 1 |
| Mifflin, SW | 1 |
| Bousquet, P | 1 |
| Feldman, J | 1 |
| Schwartz, J | 1 |
| Singh, R | 2 |
| Ticku, MK | 2 |
| Catelli, JM | 1 |
| Sved, AF | 1 |
3 reviews available for baclofen and Hypertension
| Article | Year |
|---|---|
Cough and angioedema from angiotensin-converting enzyme inhibitors: new insights into mechanisms and management.
Topics: Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Asthmat | 2004 |
gamma-Aminobutyric acid and cardiovascular function.
Topics: Animals; Atropine; Baclofen; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; | 1983 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bi | 1985 |
22 other studies available for baclofen and Hypertension
| Article | Year |
|---|---|
Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats.
Topics: Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic | 2008 |
Intrathecal baclofen for autonomic instability due to spinal cord injury.
Topics: Abdominal Wall; Antihypertensive Agents; Autonomic Dysreflexia; Baclofen; Benzimidazoles; Biphenyl C | 2009 |
Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy.
Topics: Abdominal Pain; Adolescent; Autonomic Dysreflexia; Baclofen; Cerebral Palsy; Diagnosis, Differential | 2008 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; | 2009 |
Chronic hypertension enhances presynaptic inhibition by baclofen in the nucleus of the solitary tract.
Topics: Animals; Baclofen; Baroreflex; Chronic Disease; Disease Models, Animal; GABA Agonists; Glutamic Acid | 2010 |
Cortical and hippocampal EEG effects of neurotransmitter agonists in spontaneously hypertensive vs. kainate-treated rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Baclofen; Clonidine; Disease Models, Animal; | 2011 |
Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage.
Topics: Acute Disease; Adult; Baclofen; Catheterization; Equipment Failure; Humans; Hypertension; Infusion P | 2003 |
[Acute intoxication with baclofen].
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Female; GABA Agonist | 2004 |
GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Cadmium; Calcium; Cesium; GABA Agonists; GABA Anta | 2005 |
Selected clinical aspects of acute intoxication with baclofen.
Topics: Acute Disease; Adolescent; Adult; Baclofen; Bradycardia; Coma; Creatine Kinase; Drug Overdose; Femal | 2005 |
Role of gamma-aminobutyric acid (GABA)A and GABAB receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Heart Rate; Hypertension; Male; Microinjections; Mus | 2007 |
Chronic hypertension enhances the postsynaptic effect of baclofen in the nucleus tractus solitarius.
Topics: Animals; Baclofen; Chronic Disease; Disease Models, Animal; GABA Agonists; Hypertension; Male; Neuro | 2007 |
Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats.
Topics: Action Potentials; Angiotensin II; Animals; Animals, Newborn; Baclofen; Baroreflex; Blood Pressure; | 2008 |
A hypertensive response to baclofen in the nucleus tractus solitarii in rats.
Topics: Anesthesia; Animals; Baclofen; Blood Pressure; Glutamates; Heart Rate; Hypertension; Male; Medulla O | 1981 |
Blood pressure and heart rate responses to centrally administered substance P are increased in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Baclofen; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Fe | 1980 |
Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats.
Topics: Adrenergic Fibers; Animals; Baclofen; Blood-Brain Barrier; Carbon Dioxide; Clonidine; Hydroxydopamin | 1983 |
High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method.
Topics: Animals; Baclofen; Biological Assay; Cerebral Hemorrhage; Cold Temperature; Dizocilpine Maleate; Exc | 1997 |
Age-related development of gamma-aminobutyric acid (GABA)B receptor functions in various brain regions of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Aging; Animals; Baclofen; Brain; Corpus Striatum; Cyclic AMP; GABA Agonists; gamm | 1998 |
gamma-Aminobutyric acid(B) receptor-mediated responses in the nucleus tractus solitarius are altered in acute and chronic hypertension.
Topics: Acute Disease; Animals; Baclofen; Blood Pressure; Chronic Disease; Denervation; GABA Agonists; Hyper | 2001 |
Comparison of [3H]baclofen binding to GABAB receptors in spontaneously hypertensive and normotensive rats.
Topics: Adenylyl Cyclases; Animals; Baclofen; Brain; Cerebellum; Guanosine Triphosphate; Hippocampus; Hypert | 1985 |
Central cardiovascular effects of baclofen in spontaneously hypertensive rats.
Topics: Animals; Baclofen; Blood Pressure; Brain; Heart Rate; Hypertension; Male; Phenylephrine; Pressorecep | 1987 |
Enhanced pressor response to GABA in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Topics: Animals; Baclofen; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Ma | 1988 |