Page last updated: 2024-08-21

canrenone and Hypertension

canrenone has been researched along with Hypertension in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's4 (16.67)18.2507
2000's1 (4.17)29.6817
2010's6 (25.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Armanini, D; Boscaro, M; Sabbadin, C1
Avataneo, V; Bertello, C; Buffolo, F; Burrello, J; D'Avolio, A; Mengozzi, G; Monticone, S; Mulatero, P; Pecori, A; Rabbia, F; Rumbolo, F; Veglio, F1
Blaich, C; Hoffmann, F; Johannsen, JO; Müller, C; Reuter, H; Streichert, T; Wiesen, MHJ1
D'Angelo, A; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Zoppi, A1
Armanini, D; Bordin, L; Clari, G; Donà, G; Sabbadin, C1
Bagrov, AY; Bagrov, KA; Emelianov, IV; Fedorova, OV; Frolova, EV; Grigorova, YN; Juhasz, O; Konradi, AO; Lakatta, EG; Marshall, CA; Wei, W1
Bestetti, A; D'Avino, M; Derosa, G; Felis, S; Gaudio, G; Guasti, L; Maffioli, P; Mugellini, A; Sala, C; Sarzani, R; Vanasia, M; Vulpis, V1
Camilla, R; Einaudi, S; Monticone, S; Mulatero, P; Mussa, A; Porta, F; Tessaris, D; Verna, F1
Barlocco, E; Bertolini, A; Grandi, AM; Guasti, L; Imperiale, D; Santillo, R; Venco, A1
Liedholm, H; Lindholm, L; Melander, A; Thulin, T; Wåhlin-Boll, E1
Anderton, JL; Bell, GM; Fananapazir, L1
Bianchi, G; Duzzi, L; Ferrandi, M; Ferrari, P; Minotti, E1
Claire, M; Corvol, P; Menard, J; Michaud, A; Rafestin-Oblin, ME; Roth-Meyer, C1
Berthaux, P; Forette, B; Forette, F; Henry, JF; Hervy, MP1
al Karadaghi, P; MacArthy, P; Preuss, HG; Yousufi, A1
Clough, DL; Haddy, FJ; Pamnani, MB; Whitehorn, WV1
Christiaens, L; Fenghe, D; Genard, P; Krzesinski, JM; Lomba-Pignon, MR; Palem-Vliers, M; Pequeux-Bar, ML; Rorive, G1
Garay, R; Meyer, P; Rosati, C1
Haddy, FJ; Pamnani, MB1
de Mendonça, M; Devynck, MA; Garay, R; Grichois, ML; Meyer, P; Pernollet, MG; Trouillet-Thormann, B; Wauquier, I1
Abitbol, JP; Garay, R; Girerd, X; Hannaert, P; Laurent, S; Safar, M1
Boero, R; Deabate, MC; Guarena, C; Piccoli, G; Quarello, F; Rolando, B; Rosati, C1
Boero, R; Deabate, MC; Forneris, G; Guarena, C; Piccoli, G; Quarello, F; Rosati, C1
de Mendonça, M; Devynck, MA; Garay, RP; Grichois, ML; Meyer, P; Pernollet, MG; Thormann, B; Wauquier, I1

Reviews

4 review(s) available for canrenone and Hypertension

ArticleYear
Spirolactones: clinical and pharmacologic studies.
    Advances in nephrology from the Necker Hospital, 1977, Volume: 7

    Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Kidney; Mineralocorticoid Receptor Antagonists; Pregnadienes; Protein Binding; Rats; Receptors, Cell Surface; Spironolactone

1977
[Arguments for the existence of an endogenous inhibitor of renal Na-K ATPase with steroid structure and natriuretic action].
    Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8

    Topics: Animals; Canrenone; Hypertension; Kidney; Natriuresis; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase

1990
Na+ transport in primary hypertension.
    Annals of the New York Academy of Sciences, 1986, Volume: 488

    Topics: Animals; Biological Transport, Active; Canrenone; Cell Membrane; Humans; Hypertension; Ion Channels; Natriuretic Agents; Potassium; Rats; Rats, Inbred SHR; Sodium

1986
Pharmacologic agents for the in vivo detection of vascular sodium transport defects in hypertension.
    Life sciences, 1987, Dec-21, Volume: 41, Issue:25

    Topics: Amiloride; Animals; Biological Transport, Active; Canrenone; Humans; Hypertension; Ion Channels; Ouabain; Sodium; Sodium-Potassium-Exchanging ATPase; Vascular Diseases

1987

Trials

5 trial(s) available for canrenone and Hypertension

ArticleYear
Comparative effect of canrenone or hydrochlorothiazide addition to valsartan/amlodipine combination on urinary albumin excretion in well-controlled type 2 diabetic hypertensive patients with microalbuminuria.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:4

    Topics: Adult; Aged; Albuminuria; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Canrenone; Diabetes Mellitus, Type 2; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Tetrazoles

2014
Efficacy and safety of two dosages of canrenone as add-on therapy in hypertensive patients taking ace-inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE-IT trial.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Pressure; Canrenone; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Italy; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Sodium Chloride Symporter Inhibitors; Time Factors; Treatment Outcome

2017
Aldosterone antagonist improves diastolic function in essential hypertension.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5

    Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canrenone; Diastole; Drug Administration Schedule; Echocardiography; Heart; Heart Rate; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left

2002
Comparison of single and divided daily dose spironolactone in the control of hypertension.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Blood Pressure; Canrenone; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Pregnadienes; Spironolactone

1981
[The treatment of hypertension in the elderly using a beta-blocker: acebutolol (author's transl)].
    La Nouvelle presse medicale, 1979, Sep-24, Volume: 8, Issue:36

    Topics: Acebutolol; Aged; Canrenone; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Indoles; Renin; Sulfonamides

1979

Other Studies

15 other study(ies) available for canrenone and Hypertension

ArticleYear
Primary aldosteronism: considerations about the evaluation of the aldosterone to renin ratio during canrenone treatment.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:9

    Topics: Aldosterone; Antihypertensive Agents; Canrenone; Diagnostic Techniques, Endocrine; Duration of Therapy; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineralocorticoid Receptor Antagonists; Renin; Renin-Angiotensin System; Reproducibility of Results

2021
Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism.
    The Journal of clinical endocrinology and metabolism, 2021, 08-18, Volume: 106, Issue:9

    Topics: Adolescent; Adrenalectomy; Adult; Aged; Aldosterone; Canrenone; Cohort Studies; False Negative Reactions; Female; Guidelines as Topic; Humans; Hyperaldosteronism; Hypertension; Male; Mass Screening; Medication Adherence; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Prospective Studies; Renin; Reproducibility of Results; Young Adult

2021
Reliable and easy-to-use LC-MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164

    Topics: Amlodipine; Antihypertensive Agents; Canrenone; Carbon Isotopes; Chromatography, High Pressure Liquid; Deuterium; Drug Monitoring; Drug Resistance; Humans; Hydrochlorothiazide; Hypertension; Limit of Detection; Male; Metoprolol; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry

2019
Aldosterone receptor blockers spironolactone and canrenone: two multivalent drugs.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:7

    Topics: Albuminuria; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Canrenone; Humans; Hypertension; Inflammation; Insulin Resistance; Mineralocorticoid Receptor Antagonists; Spironolactone

2014
Marinobufagenin-induced vascular fibrosis is a likely target for mineralocorticoid antagonists.
    Journal of hypertension, 2015, Volume: 33, Issue:8

    Topics: Animals; Aorta; Arterial Pressure; Bufanolides; Canrenone; Cells, Cultured; Collagen Type I; Endothelin-1; Erythrocytes; Female; Fibrosis; Humans; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitroprusside; Pulse Wave Analysis; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Spironolactone; Vasodilator Agents

2015
Polyuric-polydipsic syndrome in a pediatric case of non-glucocorticoid remediable familial hyperaldosteronism.
    Endocrine journal, 2012, Volume: 59, Issue:6

    Topics: Age of Onset; Canrenone; Child, Preschool; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Genotype; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Mutation; Phenotype; Polydipsia; Polyuria; Syndrome

2012
Influence of food intake on antihypertensive drugs: spironolactone.
    Drug-nutrient interactions, 1983, Volume: 2, Issue:3

    Topics: Adult; Blood Pressure; Canrenone; Creatinine; Female; Food; Heart Rate; Humans; Hypertension; Male; Middle Aged; Potassium; Sodium; Spironolactone

1983
Effect of canrenone and hydrochlorothiazide on the development of hypertension in rat models of genetic hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Animals; Biological Factors; Blood Pressure; Canrenone; Cardenolides; Digoxin; Disease Models, Animal; Hydrochlorothiazide; Hypertension; Rats; Rats, Inbred SHR; Saponins; Sodium-Potassium-Exchanging ATPase; Species Specificity

1993
Effects of canrenone on RRM-sucrose hypertension in WKY.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:5

    Topics: Animals; Blood Pressure; Body Weight; Canrenone; Dietary Carbohydrates; Hypertension; Kidney; Nephrectomy; Rats; Rats, Inbred WKY; Sodium, Dietary; Sucrose

1991
Effects of canrenone on blood pressure in rats with reduced renal mass.
    American journal of hypertension, 1990, Volume: 3, Issue:3

    Topics: Animals; Biological Transport, Active; Blood Pressure; Canrenone; Hypertension; Injections, Intramuscular; Male; Myocardium; Nephrectomy; Ouabain; Potassium; Pregnadienes; Rats; Rats, Inbred Strains; Renin; Sodium; Sodium-Potassium-Exchanging ATPase

1990
Antihypertensive effect of canrenone in a model where endogenous ouabain-like factors are present.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Proteins; Canrenone; Cardenolides; Digoxin; Erythrocytes; Hypertension; Ion Channels; Male; Potassium; Pregnadienes; Rats; Rats, Inbred Strains; Saponins; Sodium; Sodium-Potassium-Exchanging ATPase

1988
[Therapeutic response to canrenone of patients with essential hypertension as a function of sodium transport anomalies and ouabain sensitivity of erythrocytes].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:9

    Topics: Biological Transport; Canrenone; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Pregnadienes; Sodium Channels; Time Factors

1989
Erythrocyte Na+, K+ pump inhibition after saline infusion in essentially hypertensive subjects: effects of canrenone administration.
    International journal of cardiology, 1989, Volume: 25 Suppl 1

    Topics: Adult; Biological Transport, Active; Blood Pressure; Canrenone; Erythrocytes; Extracellular Space; Female; Humans; Hypertension; Male; Middle Aged; Ouabain; Potassium; Pregnadienes; Sodium; Sodium Chloride

1989
Effects of saline infusion and canrenone on erythrocyte Na+,K+ pump activity.
    Kidney international. Supplement, 1988, Volume: 25

    Topics: Adult; Canrenone; Erythrocytes; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Ouabain; Pregnadienes; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase

1988
[Canrenone: an effective antihypertensive in an experimental model of hypertension in which the active transport of sodium is diminished].
    Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:6

    Topics: Animals; Antihypertensive Agents; Canrenone; Cell Membrane Permeability; Creatinine; Diuresis; Hypertension; Male; Natriuresis; Ouabain; Pregnadienes; Rats; Renin; Sodium; Urea

1986