lycorine profile

lycorine: from bulbs of LYCORIS & other plants; RN given refers to (1 alpha,2 beta)-isomer; structure in Merck Index, 9th ed, #5444 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

lycorine : An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Related Flora

Pathways (1)

lycorine is involved in 1 pathway(s), involving a total of 4 unique proteins and 61 unique compounds

Flora	Rank	Flora Definition	Family	Family Definition
Crinum	genus	A plant genus of the family Amaryllidaceae that contains ALKALOIDS.[MeSH]	Amaryllidaceae	A family of herbaceous plants with bulbs or rhizomes in the order Asparagales.[MeSH]
Lycoris	genus	A plant genus of the family Amaryllidaceae. Members contain radiatine, vittatine, haemanthamine, lycorenine, dihydrolycorine, lycorine, lycoricidinol and lycoricidine.[MeSH]	Amaryllidaceae	A family of herbaceous plants with bulbs or rhizomes in the order Asparagales.[MeSH]
Crinum asiaticum	species	[no description available]	Amaryllidaceae	A family of herbaceous plants with bulbs or rhizomes in the order Asparagales.[MeSH]

ID Source	ID
PubMed CID	72378
CHEMBL ID	400092
CHEBI ID	6601
SCHEMBL ID	626071
MeSH ID	M0064502

Synonym
BRD-K64909280-001-02-7
NCI60_003767
lycoran-1alpha,2beta-diol, 3,3a-didehydro-
lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-
nsc 401360
einecs 207-503-6
galanthan-1,2-diol, 3,12-didehydro-9,10-(methylenebis(oxy))-, (1-alpha,2-beta)-
3,3a-didehydrolycoran-1alpha,2beta-diol
BIO2_000022
BIO2_000502
IDI1_033772
BCBCMAP01_000100
BSPBIO_001302
galanthidine
(-)-lycorine
amarylline
NSC683873 ,
narcissine
NSC401360 ,
2,4,5,7,12b,12c-hexahydro-1h-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, (1s,2s,12bs, 12cs)-
QTL1_000052
SMP1_000184
nsc-401360
galanthan-1, 3,12-didehydro-9,10-[methylenebis(oxy)]-, (1.alpha.,2.beta.)-
3,12-[methylenebis(oxy)]-galanthan-1.alpha.,2.beta.-diol
lycoran-1.alpha., 3,3a-didehydro-
licorine
2,5,7,12b,12c-hexahydro-1h-[1,3]-dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
galanthan-1, 3,4-didehydro-11,12-[methylenebis(oxy)]-, (1.alpha.,2.beta.)-
3,2.beta.-diol
likorin
C08532
lycorine
476-28-8
nsc-683873
NCGC00163413-01
KBIOSS_000022
KBIO3_000043
KBIO2_005158
KBIOGR_000022
KBIO2_000022
KBIO2_002590
KBIO3_000044
NCGC00163413-02
9,10-(methylenedioxy)-3,12-didehydrogalanthan-1alpha,2beta-diol
CHEBI:6601 ,
HMS1989B04
CHEMBL400092 ,
gnf-pf-4974 ,
AKOS000278045
HMS1791B04
HMS1361B04
bdbm50221066
S3903
i9q105r5bu ,
unii-i9q105r5bu
lycorine [mi]
lycoran-1.alpha.,2.beta.-diol, 3,3a-didehydro-
(1s,2s,12bs,12cs)-2,4,5,7,12b,12c-hexahydro-1h-(1,3)dioxolo(4,5-j)pyrrolo(3,2,1-de)phenanthridine-1,2-diol
CCG-208232
SCHEMBL626071
HMS3402B04
DTXSID60197208
mfcd00221746
(1s,2s,3a1s,12bs)-2,3a1,4,5,7,12b-hexahydro-1h-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
3KD ,
(1s,2s,12bs,12cs)-2,4,5,7,12b,12c-hexahydro-1h-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
Q420314
HY-N0288
NCGC00163413-07
HMS3885I12
nsc781764
nsc-781764
(1s,17s,18s,19s)-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol
CS-0008781
MS-24104
NCGC00163413-03
1h-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1s,2s,12bs,12cs)-
(1s,17s,18s,19s)-5,7-dioxa-12-azapentacyclo[10.6.1.0?,??.0?,?.0??,??]nonadeca-2,4(8),9,15-tetraene-17,18-diol

Excerpt	Reference
"Lycorine is an alkaloid with several beneficial biological properties."	( Fu, Y; Li, P; Wang, ZH; Wu, J; Wu, YX; Wu, ZX, 2021)
"Lycorine (LYC) is a benzyl phenethylamine alkaloid that exerts remarkable therapeutic effects on cancers and sepsis."	( Chen, Y; Ding, B; Gao, X; Gu, M; Wang, C; Wang, Z; Wu, X; Wu, Z; Yang, W; Yang, Y; Yin, G, 2022)
"Lycorine (Lyc) is a natural alkaloid derived from medicinal plants of the Amaryllidaceae family. "	( Li, X; Lv, F; Wang, Y, 2022)
"Lycorine is a natural plantextract that has been previously found to confer anti‑tumor activities."	( Fan, X; Li, Y; Li, Z; Liu, G; Liu, X; Zhou, Q, 2022)
"Lycorine is a reliable emetic drug in beagle dogs without serious side effects thought to be more beneficial in tolerability and efficacy than the rarely used apomorphine."	( Abraham, G; Regenthal, R, 2023)
"Lycorine is an Amaryllidaceae alkaloid that presents anti-Trichomonas vaginalis activity. "	( da Silva Trentin, D; de Oliveira Alves, E; de Souza Borges, W; Garcia, SC; Macedo, AJ; Petró-Silveira, B; Rigo, GV; Sauer, E; Tallini, LR; Tasca, T; Zuanazzi, JÂS, 2020)
"Lycorine is a phenanthridine Amaryllidaceae alkaloid isolated from the bulbs of Lycoris radiata (L'Hér.) Herb."	( Jang, MS; Jeon, S; Jin, YH; Kim, HR; Kim, S; Kwon, S; Lee, J; Min, JS; Park, CM; Park, D; Park, T; Song, JH, 2021)
"Lycorine is a potent non-nucleoside direct-acting antiviral against emerging coronavirus infections and acts by inhibiting viral RdRp activity; therefore, lycorine may be a candidate against the current COVID-19 pandemic."	( Jang, MS; Jeon, S; Jin, YH; Kim, HR; Kim, S; Kwon, S; Lee, J; Min, JS; Park, CM; Park, D; Park, T; Song, JH, 2021)
"Lycorine is an indolizidine alkaloid which is widely used for human drug design, however, application of lycorine in controlling postharvest disease and the underlying mechanisms have not been reported."	( An, B; Guo, Y; Wang, Q; Zhao, S, 2021)
"Lycorine is a novel α-syn-lowering compound that works through PKA-mediated UPS activation. "	( Cai, CZ; Chen, JY; Chen, Y; Lu, JH; Su, HX; Tan, JQ; Yuan, NN; Zhu, Q; Zhuang, XX, 2021)
"Lycorine is an alkaloid isolated from bulbs of Pancratium foetidum Pom Amaryllidaceae of the genus Lycoris. "	( Bendaif, H; Douez, C; El Ouadi, Y; Elmsellem, H; Melhaoui, A; Ramdani, M, 2018)
"Lycorine is a natural alkaloid with immense therapeutic potential."	( Feng, P; Liang, L; Liu, J; Roy, M; Xiao, X; Ye, M, 2018)
"Lycorine is a kind of natural alkaloid with anti-cancer potential. "	( Li, L; Ning, M; Yang, Q; Zhang, Z, 2019)
"Lycorine, which is a natural plant alkaloid, has been shown to possess antiviral activities against flaviviruses."	( Li, LF; Shang, LQ; Shi, PY; Wang, P; Wang, QY; Yin, Z, 2014)
"Lycorine is reported to be a multifunctional compound. "	( Cai, J; Chen, D; Cheng, J; Hao, X; Jiang, J; Jing, C; Peng, Z; Yin, J, 2015)
"Lycorine is a benzylphenethylamine-type alkaloid member of the Amaryllidaceae family. "	( Cai, JY; Chen, DZ; Hao, XJ; Jing, CX; Li, L; Li, XN; Wang, S; Wu, JB; Yin, JL, 2016)
"Lycorine is an alkaloid isolated from the bulb of the Amaryllidaceae Lycoris. "	( Cai, YM; Jiang, J; Jiao, XY; Lin, JH; Liu, XS; Wu, YE, 2009)
"Lycorine is a natural anti-tumor alkaloid extracted from Amaryllidaceae and has various biological effects on malignant cells. "	( Hu, WX; Li, Y; Liu, J; Ren, W; Shi, YW; Tang, LJ, 2007)

Excerpt	Reference
"Lycorine has a moderate antibacterial activity on the majority of strains studied, nevertheless it is more effective than Streptomycin and Ampicillin against bacteria: P."	( Bendaif, H; Douez, C; El Ouadi, Y; Elmsellem, H; Melhaoui, A; Ramdani, M, 2018)
"Lycorine has been identified and characterized by thin layer chromatography, IR and NMR (1H and 13C NMR, COZY, HMBC, HSQC and NOESY)."	( Bendaif, H; Douez, C; El Ouadi, Y; Elmsellem, H; Melhaoui, A; Ramdani, M, 2018)
"Lycorine has been revealed to inhibit the development of many kinds of malignant tumors, including glioblastoma multiforme (GBM). "	( Cheng, Z; Hu, M; Lin, L; Shen, J; Wang, H; Wang, Z; Yi, H; Zhang, T; Zhu, N, 2018)
"Lycorine has obvious antitumor effect against ACHN cells, suggesting its value as a new therapeutic agent for renal cell carcinoma."	( Huang, P; Huang, YQ; Jin, Z; Li, XZ; Liu, CX; Wang, CS; Xu, K; Zhang, YM, 2016)
"Lycorine has been reported to posses inhibitory activity against protein translation."	( Kitahara, M; Mikami, M; Yamazaki, M; Yui, S, 1998)

Excerpt	Reference
"Lycorine did not inhibit the (Na+ + K+) ATPase activity."	( Cifuentes, F; Melo, R; Quevedo, L; Sáez, JC, 1984)
"Lycorine was found to inhibit protein synthesis specifically in cultured K-ras-NRK cells."	( Atsumi, S; Koyano, T; Kushida, N; Umezawa, K, 1997)

Excerpt	Reference
"Lycorine treatment downregulated the expression levels of FABP5 and its target PPARγ, impaired AML cell viability, triggered apoptosis, and reduced triglyceride production in AML cells."	( Bai, H; Duan, J; Fan, D; Fu, W; Guo, P; He, Y; Hong, W; Liang, X; Peng, Y; Qi, X; Wu, C; Yu, W; Zhang, Q; Zhang, T; Zhou, J, 2023)
"Lycorine treatment for 14 days significantly inhibited tumor growth compared with that in controls."	( Huang, P; Jin, Z; Li, X; Liu, C; Wang, C; Wang, Q; Xu, A; Xu, N; Xu, P; Xu, Y; Zheng, J; Zheng, S, 2017)
"Lycorine treatment of mice challenged with a lethal dose of EV71 resulted in reduction of mortality, clinical scores and pathological changes in the muscles of mice, which were achieved through inhibition of viral replication."	( Liu, J; Ma, C; Qin, C; Xu, Y; Yang, Y; Zhang, L, 2011)

Role	Description
protein synthesis inhibitor	A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
antimalarial	A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
plant metabolite	Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
anticoronaviral agent	Any antiviral agent which inhibits the activity of coronaviruses.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
indolizidine alkaloid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathway	Proteins	Compounds
Amaryllidacea alkaloids biosynthesis	2	25
Amaryllidacea alkaloids biosynthesis	2	36

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	4.7444	0.5318	15.4358	37.6858	AID504845
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	10.0000	0.0355	20.9770	89.1251	AID504332
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	1.1220	0.1259	12.2344	35.4813	AID1458
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Acetylcholinesterase	Electrophorus electricus (electric eel)	IC50 (µMol)	200.0000	0.0000	0.9453	9.9400	AID1315225
Acetylcholinesterase	Homo sapiens (human)	IC50 (µMol)	177.5000	0.0000	0.9332	10.0000	AID1501977; AID311339
Cholinesterase	Equus caballus (horse)	IC50 (µMol)	200.0000	0.0000	2.2214	9.4000	AID1315224
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
acetylcholine catabolic process in synaptic cleft	Acetylcholinesterase	Homo sapiens (human)
regulation of receptor recycling	Acetylcholinesterase	Homo sapiens (human)
osteoblast development	Acetylcholinesterase	Homo sapiens (human)
acetylcholine catabolic process	Acetylcholinesterase	Homo sapiens (human)
cell adhesion	Acetylcholinesterase	Homo sapiens (human)
nervous system development	Acetylcholinesterase	Homo sapiens (human)
synapse assembly	Acetylcholinesterase	Homo sapiens (human)
receptor internalization	Acetylcholinesterase	Homo sapiens (human)
negative regulation of synaptic transmission, cholinergic	Acetylcholinesterase	Homo sapiens (human)
amyloid precursor protein metabolic process	Acetylcholinesterase	Homo sapiens (human)
positive regulation of protein secretion	Acetylcholinesterase	Homo sapiens (human)
retina development in camera-type eye	Acetylcholinesterase	Homo sapiens (human)
acetylcholine receptor signaling pathway	Acetylcholinesterase	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Acetylcholinesterase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
amyloid-beta binding	Acetylcholinesterase	Homo sapiens (human)
acetylcholinesterase activity	Acetylcholinesterase	Homo sapiens (human)
cholinesterase activity	Acetylcholinesterase	Homo sapiens (human)
protein binding	Acetylcholinesterase	Homo sapiens (human)
collagen binding	Acetylcholinesterase	Homo sapiens (human)
hydrolase activity	Acetylcholinesterase	Homo sapiens (human)
serine hydrolase activity	Acetylcholinesterase	Homo sapiens (human)
acetylcholine binding	Acetylcholinesterase	Homo sapiens (human)
protein homodimerization activity	Acetylcholinesterase	Homo sapiens (human)
laminin binding	Acetylcholinesterase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular region	Acetylcholinesterase	Homo sapiens (human)
basement membrane	Acetylcholinesterase	Homo sapiens (human)
extracellular space	Acetylcholinesterase	Homo sapiens (human)
nucleus	Acetylcholinesterase	Homo sapiens (human)
Golgi apparatus	Acetylcholinesterase	Homo sapiens (human)
plasma membrane	Acetylcholinesterase	Homo sapiens (human)
cell surface	Acetylcholinesterase	Homo sapiens (human)
membrane	Acetylcholinesterase	Homo sapiens (human)
neuromuscular junction	Acetylcholinesterase	Homo sapiens (human)
synaptic cleft	Acetylcholinesterase	Homo sapiens (human)
synapse	Acetylcholinesterase	Homo sapiens (human)
perinuclear region of cytoplasm	Acetylcholinesterase	Homo sapiens (human)
side of membrane	Acetylcholinesterase	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (210)

Assay ID	Title	Year	Journal	Article
AID688344	Cytotoxicity against human CEM cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID334836	Cytotoxicity against human KBV1 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID449706	NOVARTIS: Inhibition Frequency Index (IFI) - the number of HTS assays where a compound showed > 50% inhibition/induction, expressed as a percentage of the number of assays in which the compound was tested.	2008	Proceedings of the National Academy of Sciences of the United States of America, Jul-01, Volume: 105, Issue:26	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
AID1068720	Growth inhibition of human MCF7 cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID1315225	Inhibition of electric eel AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 5 mins by DTNB-based spectrophotometric analysis	2016	Journal of natural products, 05-27, Volume: 79, Issue:5	Alkaloids from Hippeastrum argentinum and Their Cholinesterase-Inhibitory Activities: An in Vitro and in Silico Study.
AID1599335	Antiviral activity against dengue virus	2019	European journal of medicinal chemistry, Aug-15, Volume: 176	Recent update on anti-dengue drug discovery.
AID1068717	Growth inhibition of human Hs683 cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID336623	Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID336624	Therapeutic index, ratio of TC50 for african green monkey Vero cells to IC50 for Rift valley fever virus	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID438124	Growth inhibition of proapoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1366147	Antibacterial activity against Flavobacterium columnare BioMed after 24 hrs	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID400158	Therapeutic index, ratio of cytotoxicity against african green monkey Vero cells to antiviral activity against Semliki forest virus
AID399870	Antiviral activity against Semliki forest virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 10 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID438150	Antitumor activity against mouse B16F10 cells implanted in B6D2F1 mouse assessed as increase in mouse survival at 40 mg/kg, iv administered thrice weekly for 3 consecutive weeks starting from 5th day post tumor grafting	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID688350	Cytotoxicity against human G361 cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID1501977	Inhibition of AChE (unknown origin)	2017	Journal of natural products, 09-22, Volume: 80, Issue:9	Acetylcholinesterase Inhibitory Alkaloids from the Whole Plants of Zephyranthes carinata.
AID1317850	Inhibition of translation in human HeLaS3 assessed as increase in eIF2alpha phosphorylation at 50 uM after 1 hr by Western blot analysis	2016	European journal of medicinal chemistry, Sep-14, Volume: 120	5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells.
AID688351	Cytotoxicity against human BJ cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID977599	Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	2013	Molecular pharmacology, Jun, Volume: 83, Issue:6	Structure-based identification of OATP1B1/3 inhibitors.
AID402997	Cytotoxicity against mouse ddY macrophages assessed as cell viability at 100 um after 72 hrs by MTT assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID334831	Cytotoxicity against human HT1080 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID1717751	Antiviral activity against wild type HCoV-OC43 infected in BHK-21 cells incubated for 72 hrs by RT-PCR method	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID632108	Growth inhibition of human PC3 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID438134	Inhibition of cytokinesis in proapoptotic stimuli-resistant human U373 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID438128	Growth inhibition of human WI38 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID449703	NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay	2008	Proceedings of the National Academy of Sciences of the United States of America, Jul-01, Volume: 105, Issue:26	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
AID1578100	Antiplasmodial activity against Entamoeba histolytica	2019	Bioorganic & medicinal chemistry letters, 10-15, Volume: 29, Issue:20	Antiprotozoal alkaloid principles of the plant family Amaryllidaceae.
AID334845	Selectivity index, ratio of ED50 for human KB cells to ED50 for Plasmodium falciparum W2	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID336617	Therapeutic index, ratio of TC50 for african green monkey Vero cells to IC50 for Dengue type 4 virus	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID1717767	Cytotoxicity against African green monkey Vero E6 cells incubated for 72 hrs by MTS assay	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID400138	Antiviral activity against Measles virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID718092	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID400153	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction of virus-induced cytopathic effect at < 1 ug/mL after 4 days
AID718088	Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human HL60 cells	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID334843	Antimalarial activity after 24 hrs against Plasmodium falciparum W2 infected in type A+ human erythrocytes by [3H]hypoxanthine uptake	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID400157	Therapeutic index, ratio of cytotoxicity against african green monkey Vero cells to antiviral activity against Herpes simplex virus
AID336614	Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID491769	Antiplasmodial activity against Plasmodium falciparum F32-Tanzania after 24 hrs	2010	Bioorganic & medicinal chemistry, Jul-01, Volume: 18, Issue:13	Synthesis and antiplasmodial activity of lycorine derivatives.
AID688348	Cytotoxicity against human MCF7 cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID336615	Therapeutic index, ratio of TC50 for african green monkey Vero cells to IC50 for Yellow fever virus Ashibi	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID718094	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID438133	Reduction in mitosis occurrence in proapoptotic stimuli-resistant human A549 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1366137	Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 1 mg/ml	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID1717769	Antiviral activity against HCoV-NL63 infected in Rhesus macaque LLC-MK2 cells incubated for 72 hrs by RT-PCR method	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID1317849	Inhibition of translation in human HeLaS3 assessed as induction of intact polysomes at 50 uM after 1 hr by UV-based 35S-methionine metabolic labeling method	2016	European journal of medicinal chemistry, Sep-14, Volume: 120	5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells.
AID400155	Therapeutic index, ratio of cytotoxicity against african green monkey Vero cells to antiviral activity against Poliovirus
AID400146	Cytotoxicity against Herpes simplex virus infected african green monkey Vero cells assessed as monolayer destruction at 50 ug/mL
AID438131	Cytotoxic activity against proapoptotic stimuli-resistant human A549 cells assessed as induction of cell death at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1717752	cytotoxicity against golden hamster BHK-21 cells incubated for 72 hrs by MTT assay	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID438145	Induction of apoptosis in human MCF7 cells after 72 hrs by annexin-V/propidium iodide staining based flow cytometry	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID399865	Antiviral activity against Herpes simplex virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID399875	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 20 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID334840	Cytotoxicity against human ZR-75-1 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID311338	Antiviral activity against Tobacco mosaic virus U1 after 72 hrs by half leaf method	2007	Journal of natural products, Sep, Volume: 70, Issue:9	Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase.
AID1578101	Antiplasmodial activity against Trichomonas vaginalis assessed as reduction in plasmodium viability at 250 ug/ml at relative to control	2019	Bioorganic & medicinal chemistry letters, 10-15, Volume: 29, Issue:20	Antiprotozoal alkaloid principles of the plant family Amaryllidaceae.
AID399334	In vivo antitumor activity against mouse P388 cells at 75 mg/kg
AID400145	Cytotoxicity against Measles virus infected african green monkey Vero cells assessed as monolayer destruction at 100 ug/mL
AID479394	Growth inhibition of apoptosis-resistant human U373 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID1379374	Antiviral activity against EV71 695F infected in ICR mouse assessed as effect on clinical score at 0.4 mg/kg, ip qd administered for 7 days dosed prior to viral infection measured for 2 weeks	2017	ACS medicinal chemistry letters, Aug-10, Volume: 8, Issue:8	Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD.
AID1068718	Growth inhibition of human SK-MEL-28 cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID438137	Increase in polymerized actin levels in proapoptotic stimuli-resistant human U373 cells at 5 uM after 6 hrs by fluorescence microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID399863	Antiviral activity against Herpes simplex virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 20 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID1578098	Antitrypanosomal activity against Trypanosoma brucei rhodesiense	2019	Bioorganic & medicinal chemistry letters, 10-15, Volume: 29, Issue:20	Antiprotozoal alkaloid principles of the plant family Amaryllidaceae.
AID400150	Cytotoxicity against african green monkey Vero cells assessed as monolayer destruction at 10 ug/mL after 24 hrs by trypan blue exclusion test
AID336612	Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID718084	Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human HT-29 cells	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID438138	Increase in polymerized actin levels in proapoptotic stimuli-resistant human A549 cells at 5 uM after 6 hrs by fluorescence microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID402995	Cytotoxicity against mouse ddY macrophages assessed as cell viability at 30 um after 72 hrs by MTT assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID479401	Cytostatic effect against apoptosis-sensitive mouse B16F10 cells assessed as impairment of cell population development at 20 uM by quantitative video microscopy	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID438121	Cytotoxic activity against proapoptotic stimuli-resistant human U373 cells assessed as induction of cell death at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID400143	Cytotoxicity against Semliki forest virus infected african green monkey Vero cells assessed as monolayer destruction at 100 ug/mL
AID491981	Cytotoxicity against human U373 cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID399864	Antiviral activity against Herpes simplex virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 10 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID1379373	Antiviral activity against EV71 695F infected in ICR mouse assessed as decrease in body weight loss at 0.4 mg/kg, ip qd administered for 7 days dosed prior to viral infection measured for 2 weeks	2017	ACS medicinal chemistry letters, Aug-10, Volume: 8, Issue:8	Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD.
AID688347	Cytotoxicity against human K562 cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID334841	Cytotoxicity against human U373 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID632907	Inhibition of human topoisomerase 1-mediated relaxation of supercoiled pBR322 DNA	2011	Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23	Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.
AID400139	Antiviral activity against Measles virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 2.5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID449704	NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay	2008	Proceedings of the National Academy of Sciences of the United States of America, Jul-01, Volume: 105, Issue:26	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
AID400133	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 2.5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID400137	Antiviral activity against Measles virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 10 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID402989	Cytotoxicity against mouse ddY macrophages assessed as cell viability at 1 um after 72 hrs by MTT assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID438147	Induction of apoptosis in human U373 cells at 50 uM after 72 hrs by annexin-V/propidium iodide staining based flow cytometry	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID402994	Inhibition of LPS-induced NO production in ddY mouse macrophages at 30 uM after 20 hrs by Griess reagent assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID491978	Cytotoxicity against human A549 cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID491979	Cytotoxicity against human OE21 cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID438132	Reduction in mitosis occurrence in proapoptotic stimuli-resistant human U373 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID438125	Growth inhibition of proapoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID438152	Toxicity in iv dosed mouse assessed as reduction of body weight at 5 to 80 mg/kg, iv administered once daily for 5 consecutive days measured after 28 days	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID718093	Cytotoxicity against human K562 cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID399872	Antiviral activity against Semliki forest virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 2.5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID632910	Binding affinity to calf thymus DNA assessed as change in absorption spectra at increasing concentration at pH 8 by UV-Vis spectra analysis	2011	Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23	Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.
AID400144	Cytotoxicity against Poliovirus infected african green monkey Vero cells assessed as monolayer destruction at 100 ug/mL
AID399876	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 10 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID1366152	Antibacterial activity against Staphylococcus aureus	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID438139	Inhibition of cell migration of proapoptotic stimuli-resistant human U373 cells at 5 uM by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID336616	Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID336613	Therapeutic index, ratio of TC50 for african green monkey Vero cells to IC50 for Japanese encephalitis virus Nakayama	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID334844	Selectivity index, ratio of ED50 for human KB cells to ED50 for Plasmodium falciparum D6	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID688349	Cytotoxicity against human HeLa cells after 72 hrs by Calcein AM assay	2012	Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19	Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
AID491983	Cytotoxicity against mouse B16F10 cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID648673	Antiviral activity against Human enterovirus 71 infected in mouse assessed as increase in survival rate	2012	Bioorganic & medicinal chemistry letters, Mar-15, Volume: 22, Issue:6	Antiviral effect of geraniin on human enterovirus 71 in vitro and in vivo.
AID491980	Cytotoxicity against human Hs683 cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID438143	Reduction of colony formation in undifferentiated proapoptotic stimuli-resistant human A549 cells at 0.5 uM under anchorage-independent culture conditions by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID479399	Growth inhibition of apoptosis-sensitive mouse B16F10 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID1717768	Selectivity ratio of CC50 for HAE cells to EC50 for SARS-CoV BJ-001 infected in African green monkey Vero E6 cells	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID402996	Inhibition of LPS-induced NO production in ddY mouse macrophages at 100 uM after 20 hrs by Griess reagent assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID718091	Cytotoxicity against human A549 cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID438148	Induction of non-apoptotic cell death in human U373 cells at 50 uM after 72 hrs by annexin-V/propidium iodide staining based flow cytometry	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID438129	Growth inhibition of human WS1 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1895509	Antiviral activity against Zika virus NS5/RNA-dependent RNA polymerase	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
AID438122	Cytostatic activity against proapoptotic stimuli-resistant human A549 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1315224	Inhibition of equine serum BuChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 5 mins by DTNB-based spectrophotometric analysis	2016	Journal of natural products, 05-27, Volume: 79, Issue:5	Alkaloids from Hippeastrum argentinum and Their Cholinesterase-Inhibitory Activities: An in Vitro and in Silico Study.
AID402991	Cytotoxicity against mouse ddY macrophages assessed as cell viability at 3 um after 72 hrs by MTT assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID400141	Cytotoxicity against Poliovirus infected african green monkey Vero cells assessed as monolayer destruction at > 25 ug/mL
AID479398	Growth inhibition of apoptosis-sensitive human Hs 683 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID1068721	Growth inhibition of human A549 cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID1379366	Antiviral activity against EV71 695F infected in ICR mouse assessed as protection against viral infection by measuring mouse survival at 0.4 mg/kg, ip qd administered for 7 days dosed prior to viral infection measured on day 14 relative to control	2017	ACS medicinal chemistry letters, Aug-10, Volume: 8, Issue:8	Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD.
AID1068716	Growth inhibition of mouse B16F10 cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID334838	Cytotoxicity against human A431 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID718086	Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human A549 cells	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID438123	Cytostatic activity against proapoptotic stimuli-resistant human U373 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID334839	Cytotoxicity against human LNCAP cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID632104	Growth inhibition of pro-apoptotic stimuli-resistant human U373 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID438120	Growth inhibition of proapoptotic stimuli-resistant human OE21 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1717753	Selectivity index, ratio of CC50 for golden hamster BHK-21 cells to EC50 for wild type HCoV-OC43 infected in BHK-21 cells	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID400140	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction of virus-induced cytopathic effect at 1 ug/mL after 96 hrs by microscopy
AID1717765	Antiviral activity against SARS-CoV BJ-001 infected in African green monkey Vero E6 cells assessed as reduction in virus induced cytopathic effect by visual observation	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID479395	Growth inhibition of apoptosis-resistant human A549 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID632103	Growth inhibition of pro-apoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID1366144	Antibacterial activity against Corynebacterium fascians assessed as diameter of inhibition zone at 10 mM after 48 to 72 hrs by paper disc method	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID491982	Cytotoxicity against human SK-MEL cells after 72 hrs by MTT colorimetric assay	2010	Journal of natural products, Jul-23, Volume: 73, Issue:7	Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
AID438146	Induction of apoptosis in human U373 cells at 5 uM after 72 hrs by annexin-V/propidium iodide staining based flow cytometry	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1578099	Antiplasmodial activity against Trichomonas vaginalis assessed as reduction in plasmodium viability at 125 ug/ml relative to control	2019	Bioorganic & medicinal chemistry letters, 10-15, Volume: 29, Issue:20	Antiprotozoal alkaloid principles of the plant family Amaryllidaceae.
AID334833	Cytotoxicity against human SK-MEL-2 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID1068719	Growth inhibition of human T98G cells by MTT assay	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID438149	Toxicity in iv dosed mouse administered once daily for 5 consecutive days measured after 28 days	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1717766	Antiviral activity against SARS-CoV BJ-001 infected in African green monkey Vero E6 cells assessed as reduction in virus induced cytopathic effect incubated for 72 hrs by MTS/phenazine methosulfate method	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID334835	Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID438127	Growth inhibition of proapoptotic stimuli-sensitive mouse B16F10 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1717771	Selectivity ratio of CC50 for Rhesus macaque LLC-MK2 cells to EC50 for HCoV-NL63 infected in Rhesus macaque LLC-MK2 cells	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID632106	Growth inhibition of pro-apoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID334837	Cytotoxicity against mouse P388 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID400151	Cytotoxicity against african green monkey Vero cells assessed as monolayer destruction at 25 ug/mL after 24 hrs by trypan blue exclusion test
AID402990	Inhibition of LPS-induced NO production in ddY mouse macrophages at 3 uM after 20 hrs by Griess reagent assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID400148	Cytotoxicity against Poliovirus infected african green monkey Vero cells assessed as monolayer destruction at 50 ug/mL
AID1366145	Antibacterial activity against Edwardsiella ictaluri after 24 hrs	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID400132	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID400156	Effect on african green monkey Vero cell growth assessed as doubling of cell generation at 1 ug/mL after 24 hrs by trypan blue exclusion test
AID479396	Growth inhibition of apoptosis-resistant human SK-MEL-28 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID438130	Growth inhibition of human NHDF after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID399869	Antiviral activity against Semliki forest virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 20 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID399871	Antiviral activity against Semliki forest virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID336625	Antiviral activity against Sandfly fever sicilian virus infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID400159	Therapeutic index, ratio of cytotoxicity against african green monkey Vero cells to antiviral activity against Measles virus
AID334834	Cytotoxicity against human Col1 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID402992	Inhibition of LPS-induced NO production in ddY mouse macrophages at 10 uM after 20 hrs by Griess reagent assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID438141	Reduction of colony formation in undifferentiated proapoptotic stimuli-resistant human U373 cells at 0.5 uM under anchorage-independent culture conditions by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID400136	Antiviral activity against Measles virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 20 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID402998	Inhibition of LPS-induced NO production in ddY mouse macrophages after 20 hrs by Griess reagent assay	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID479397	Growth inhibition of apoptosis-resistant human OE21 cells after 72 hrs by MTT assay	2010	Journal of natural products, May-28, Volume: 73, Issue:5	Investigations of fungal secondary metabolites with potential anticancer activity.
AID718089	Cytotoxicity against human BEAS2B cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID632102	Growth inhibition of human MCF7 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID718085	Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human HepG2 cells	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID438135	Inhibition of cytokinesis in proapoptotic stimuli-resistant human A549 cells at 5 uM after 72 hrs by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID718087	Selectivity index, ratio of IC50 for human BEAS2B cells to IC50 for human K562 cells	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID1717809	Antiviral activity against HCoV-OC43 infected in BALB/c mouse assessed as protection against virus-induced lethal infection at 15 mg/kg, ip administered for 14 days and measured up to 20 days	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID1717770	Cytotoxicity against Rhesus macaque LLC-MK2 cells incubated for 72 hrs by MTT assay	2020	Journal of medicinal chemistry, 11-25, Volume: 63, Issue:22	Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
AID438142	Reduction of colony formation in undifferentiated proapoptotic stimuli-resistant human U373 cells at 5 uM under anchorage-independent culture conditions by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID420064	Inhibition of human CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline	2009	Bioorganic & medicinal chemistry letters, Jun-15, Volume: 19, Issue:12	Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids.
AID402993	Cytotoxicity against mouse ddY macrophages assessed as cell viability at 10 um after 72 hrs by MTT assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID1366138	Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 1 mg/ml	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID334842	Antimalarial activity after 24 hrs against Plasmodium falciparum D6 infected type A+ human erythrocytes by [3H]hypoxanthine uptake	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID632107	Growth inhibition of pro-apoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID400149	Cytotoxicity against Measles virus infected african green monkey Vero cells assessed as monolayer destruction at 50 ug/mL
AID400152	Cytotoxicity against african green monkey Vero cells assessed as monolayer destruction at 50 ug/mL after 24 hrs by trypan blue exclusion test
AID632101	Growth inhibition of pro-apoptotic stimuli-sensitive human Hs683 cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID977602	Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM	2013	Molecular pharmacology, Jun, Volume: 83, Issue:6	Structure-based identification of OATP1B1/3 inhibitors.
AID438119	Growth inhibition of proapoptotic stimuli-resistant human A549 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1068715	Lipophilicity, log P of the compound	2014	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 24, Issue:3	C1,C2-ether derivatives of the Amaryllidaceae alkaloid lycorine: retention of activity of highly lipophilic analogues against cancer cells.
AID400154	Antiviral activity against Poliovirus infected african green monkey Vero cells assessed as reduction of virus-induced cytopathic effect at 1 ug/mL after 4 days
AID438140	Inhibition of cell migration of proapoptotic stimuli-resistant human A549 cells at 5 uM by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID718090	Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay	2012	Journal of natural products, Dec-28, Volume: 75, Issue:12	Cytotoxic alkaloids from the whole plants of Zephyranthes candida.
AID632906	Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 DNA	2011	Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23	Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases.
AID400147	Cytotoxicity against Semliki forest virus infected african green monkey Vero cells assessed as monolayer destruction at 50 ug/mL
AID438126	Growth inhibition of proapoptotic stimuli-resistant human SK-MEL-28 cells after 72 hrs by MTT assay	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID438144	Reduction of colony formation in undifferentiated proapoptotic stimuli-resistant human A549 cells at 5 uM under anchorage-independent culture conditions by quantitative video microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID1366146	Antibacterial activity against Flavobacterium columnare ALM-00-173 after 24 hrs	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Antibacterial constituents of the plant family Amaryllidaceae.
AID399866	Antiviral activity against Herpes simplex virus infected african green monkey Vero cells assessed as reduction in virus-induced cytopathic effect at 2.5 ug/mL after 96 hrs measured as viral titer per ml by microscopy
AID402988	Inhibition of LPS-induced NO production in ddY mouse macrophages at 1 uM after 20 hrs by Griess reagent assay relative to control	2004	Journal of natural products, Jul, Volume: 67, Issue:7	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.
AID438151	Antitumor activity against mouse B16F10 cells implanted in iv dosed B6D2F1 mouse assessed as active dose increasing mouse survival administered thrice weekly for 3 consecutive weeks starting from 5th day post tumor grafting	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID336622	Therapeutic index, ratio of TC50 for african green monkey Vero cells to IC50 for Punta toro virus Adames	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID336621	Antiviral activity against Punta Toro virus Adames infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	1992	Journal of natural products, Nov, Volume: 55, Issue:11	Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances.
AID449705	NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)	2008	Proceedings of the National Academy of Sciences of the United States of America, Jul-01, Volume: 105, Issue:26	In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
AID632105	Growth inhibition of pro-apoptotic stimuli-resistant human T98G cells after 72 hrs by MTT assay	2011	Bioorganic & medicinal chemistry, Dec-01, Volume: 19, Issue:23	In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
AID501441	Inhibition of AChE at 10 uM by Ellman's assay	2010	Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17	Structure-activity studies on acetylcholinesterase inhibition in the lycorine series of Amaryllidaceae alkaloids.
AID334830	Cytotoxicity against human BCA1 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID1895510	Cytotoxicity against African green monkey Vero cells	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
AID1845480	Antiviral activity against SARS-CoV assessed as reduction in virus-induced cytopathic effect	2021	Journal of natural products, 01-22, Volume: 84, Issue:1	Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2.
AID438136	Increase in actin cytoskeleton rigidity in proapoptotic stimuli-resistant human U373 cells at 5 uM after 72 hrs by fluorescence microscopy	2009	Journal of medicinal chemistry, Oct-22, Volume: 52, Issue:20	Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
AID400142	Cytotoxicity against Herpes simplex virus infected african green monkey Vero cells assessed as monolayer destruction at 100 ug/mL
AID311339	Inhibition of AChE by Ellman method	2007	Journal of natural products, Sep, Volume: 70, Issue:9	Benzylphenethylamine alkaloids from Hosta plantaginea with inhibitory activity against tobacco mosaic virus and acetylcholinesterase.
AID492425	Antimalarial activity against Plasmodium falciparum	2009	Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue:9	Antimalarials from nature.
AID334832	Cytotoxicity against human LUC1 cells after 3 days by sulforhodamine B assay	1993	Journal of natural products, Aug, Volume: 56, Issue:8	Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
AID588519	A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities	2011	Antiviral research, Sep, Volume: 91, Issue:3	High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID1745854	NCATS anti-infectives library activity on HEK293 viability as a counter-qHTS vs the C. elegans viability qHTS	2023	Disease models & mechanisms, 03-01, Volume: 16, Issue:3	In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
AID1745855	NCATS anti-infectives library activity on the primary C. elegans qHTS viability assay	2023	Disease models & mechanisms, 03-01, Volume: 16, Issue:3	In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
AID540299	A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis	2010	Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21	Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID602156	Novartis GNF Liver Stage Dataset: Malariabox Annotation	2011	Science (New York, N.Y.), Dec-09, Volume: 334, Issue:6061	Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
AID1159550	Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening	2015	Nature cell biology, Nov, Volume: 17, Issue:11	6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	16 (6.99)	18.7374
1990's	13 (5.68)	18.2507
2000's	32 (13.97)	29.6817
2010's	112 (48.91)	24.3611
2020's	56 (24.45)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	15 (6.28%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	224 (93.72%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
narciclasine	[no description available]	medium	20	phenanthridines	metabolite
lycoricidine	[no description available]	medium	3	phenanthridines
trans-dihydronarciclasine	[no description available]	medium	2
pancratistatin	[no description available]	medium	7	citraconoyl group
pseudolycorine	[no description available]	medium	10	phenanthridines
7-deoxypancratistatin	[no description available]	medium	2	phenanthridines
7-deoxy-trans-dihydronarciclasine	[no description available]	medium	2
chloroquine	[no description available]	medium	7	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
mefloquine hydrochloride	[no description available]	medium	3	organofluorine compound; piperidines; quinolines; secondary alcohol
quinine	[no description available]	medium	2	cinchona alkaloid	antimalarial; muscle relaxant; non-narcotic analgesic
bis(2-guanidinoethyl)disulfide	[no description available]	medium	1
omega-n-methylarginine	[no description available]	medium	1	amino acid zwitterion; arginine derivative; guanidines; L-arginine derivative; non-proteinogenic L-alpha-amino acid
trispheridine	[no description available]	medium	5	phenanthridines
caffeic acid phenethyl ester	[no description available]	medium	1	alkyl caffeate ester	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiviral agent; immunomodulator; metabolite; neuroprotective agent
herbimycin	[no description available]	medium	1
tacrine	[no description available]	medium	1	acridines; aromatic amine	EC 3.1.1.7 (acetylcholinesterase) inhibitor
galantamine	[no description available]	medium	28	benzazepine alkaloid fundamental parent; benzazepine alkaloid; organic heterotetracyclic compound; tertiary amino compound	antidote to curare poisoning; cholinergic drug; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant metabolite
ribavirin	[no description available]	medium	5	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide	anticoronaviral agent; antiinfective agent; antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
hemanthamine	[no description available]	medium	5	alkaloid
1-O-Acetyllycorine	[no description available]	medium	9	alkaloid
sanguinine	[no description available]	medium	2	benzazepine
antofine	[no description available]	medium	1	alkaloid antibiotic; alkaloid; aromatic ether; organic heteropentacyclic compound	angiogenesis inhibitor; anti-inflammatory agent; antimicrobial agent; antineoplastic agent; antiviral agent; phytotoxin; plant metabolite
ungeremine	[no description available]	medium	6	organic molecular entity	metabolite
quinacrine	[no description available]	medium	3	acridines; aromatic ether; organochlorine compound; tertiary amino compound	antimalarial; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
1,3-dipropyl-8-cyclopentylxanthine	[no description available]	medium	2	oxopurine	adenosine A1 receptor antagonist; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
1-aminoindan-1,5-dicarboxylic acid	[no description available]	medium	2
astemizole	[no description available]	medium	2	benzimidazoles; piperidines	anti-allergic agent; anticoronaviral agent; H1-receptor antagonist
aricine	[no description available]	medium	2	cinchona alkaloid
clotrimazole	[no description available]	medium	2	conazole antifungal drug; imidazole antifungal drug; imidazoles; monochlorobenzenes	antiinfective agent; environmental contaminant; xenobiotic
moclobemide	[no description available]	medium	2	benzamides; monochlorobenzenes; morpholines	antidepressant; environmental contaminant; xenobiotic
n-acetyl-4-nitrophenylserinol	[no description available]	medium	2
oxiracetam	[no description available]	medium	2	organonitrogen compound; organooxygen compound
pentamidine	[no description available]	medium	2	aromatic ether; carboxamidine; diether	anti-inflammatory agent; antifungal agent; calmodulin antagonist; chemokine receptor 5 antagonist; EC 2.3.1.48 (histone acetyltransferase) inhibitor; NMDA receptor antagonist; S100 calcium-binding protein B inhibitor; trypanocidal drug; xenobiotic
pronethalol	[no description available]	medium	2	naphthalenes
propafenone	[no description available]	medium	2	aromatic ketone; secondary alcohol; secondary amino compound	anti-arrhythmia drug
pyrimethamine	[no description available]	medium	2	aminopyrimidine; monochlorobenzenes	antimalarial; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
scriptaid	[no description available]	medium	3	isoquinolines
6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nona(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone	[no description available]	medium	2	cyclodepsipeptide
cycloheximide	[no description available]	medium	5	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor
phanquinone	[no description available]	medium	2	orthoquinones
diphenan	[no description available]	medium	2	diarylmethane
2-phenylacetamide	[no description available]	medium	2	monocarboxylic acid amide	mouse metabolite
tetraphenylborate	[no description available]	medium	2
cycloguanil hydrochloride	[no description available]	medium	2	hydrochloride; organic molecular entity
emetine	[no description available]	medium	4	isoquinoline alkaloid; pyridoisoquinoline	antiamoebic agent; anticoronaviral agent; antiinfective agent; antimalarial; antineoplastic agent; antiprotozoal drug; antiviral agent; autophagy inhibitor; emetic; expectorant; plant metabolite; protein synthesis inhibitor
dequalinium chloride	[no description available]	medium	2	organic chloride salt	antifungal agent; antineoplastic agent; antiseptic drug; mitochondrial NADH:ubiquinone reductase inhibitor
gentian violet	[no description available]	medium	1	organic chloride salt	anthelminthic drug; antibacterial agent; antifungal agent; antiseptic drug; histological dye
Berberine chloride (TN)	[no description available]	medium	2	organic molecular entity
9,10-dimethylanthracene	[no description available]	medium	2
c 137	[no description available]	medium	2
buquinolate	[no description available]	medium	2
propranolol glycol	[no description available]	medium	2
thionine	[no description available]	medium	1
neocuproine	[no description available]	medium	2	phenanthrolines	chelator; copper chelator
mefloquine hydrochloride	[no description available]	medium	2	hydrochloride
toxoflavin	[no description available]	medium	2	carbonyl compound; pyrimidotriazine	antibacterial agent; antineoplastic agent; apoptosis inducer; bacterial metabolite; toxin; virulence factor; Wnt signalling inhibitor
selfotel	[no description available]	medium	1	non-proteinogenic alpha-amino acid
plasmenylserine	[no description available]	medium	2	O-phosphoserine	EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor; EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor; EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
2,2',2''-terpyridine	[no description available]	medium	2	terpyridines	chelator
cletoquine	[no description available]	medium	2
bathophenanthroline	[no description available]	medium	2	benzenes; phenanthrolines	chelator
fascaplysine	[no description available]	medium	1
tryptanthrine	[no description available]	medium	2	alkaloid antibiotic; organic heterotetracyclic compound; organonitrogen heterocyclic compound
ethylhydrocupreine	[no description available]	medium	2	aromatic ether; cinchona alkaloid	EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
cinchonine	[no description available]	medium	2	(8xi)-cinchonan-9-ol; cinchona alkaloid	metabolite
7-chloro-4-aminoquinoline	[no description available]	medium	2	aminoquinoline
mmv665852	[no description available]	medium	2
1,3,4,10-Tetrahydro-9(2H)-acridinone	[no description available]	medium	2	acridines
wr 158122	[no description available]	medium	2
dihydroergocristine	[no description available]	medium	2	ergot alkaloid	adrenergic antagonist; vasodilator agent
3',4'-dichlorobenzamil	[no description available]	medium	2	guanidines; pyrazines
cleistanthin b	[no description available]	medium	2	beta-D-glucoside; cleistanthins; monosaccharide derivative	alpha-adrenergic antagonist; antihypertensive agent; diuretic
n-acetyltyramine	[no description available]	medium	2	acetamides; tyramines	animal metabolite; Aspergillus metabolite; bacterial metabolite; marine metabolite; quorum sensing inhibitor
1,3-di(4-imidazolinophenoxyl)propane	[no description available]	medium	2
7h-pyrido(4,3-c)carbazole	[no description available]	medium	2
cl 246738	[no description available]	medium	2
celastrol methyl ester	[no description available]	medium	3	carboxylic ester
2-phenyl-4-oxohydroquinoline	[no description available]	medium	2
cypripedin	[no description available]	medium	2	phenanthrol
respinomycin d	[no description available]	medium	2
azacrin	[no description available]	medium	1
acetoxycycloheximide	[no description available]	medium	2
(R)-Roemerine	[no description available]	medium	2	isoquinoline alkaloid
anisomycin	[no description available]	medium	3	monohydroxypyrrolidine; organonitrogen heterocyclic antibiotic	anticoronaviral agent; antimicrobial agent; antineoplastic agent; antiparasitic agent; bacterial metabolite; DNA synthesis inhibitor; protein synthesis inhibitor
2-guanidine-4-methylquinazoline	[no description available]	medium	2
jatrorrhizine chloride	[no description available]	medium	1
puromycin	[no description available]	medium	2	puromycins	antiinfective agent; antimicrobial agent; antineoplastic agent; EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor; EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor; nucleoside antibiotic; protein synthesis inhibitor
quinidine	[no description available]	medium	3	cinchona alkaloid	alpha-adrenergic antagonist; anti-arrhythmia drug; antimalarial; drug allergen; EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor; EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; muscarinic antagonist; P450 inhibitor; potassium channel blocker; sodium channel blocker
trichostatin a	[no description available]	medium	1	antibiotic antifungal agent; hydroxamic acid; trichostatin	bacterial metabolite; EC 3.5.1.98 (histone deacetylase) inhibitor; geroprotector
epothilone b	[no description available]	medium	2	epothilone; epoxide	antineoplastic agent; apoptosis inducer; microtubule-stabilising agent
dactinomycin	[no description available]	medium	2	actinomycin	mutagen
1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	[no description available]	medium	2	pyrimidotriazine
jp-1302	[no description available]	medium	2
7-hydroxy-2-methoxy-1,4-phenanthrenedione	[no description available]	medium	2
cgp 60474	[no description available]	medium	2	substituted aniline
2-[2-hydroxy-6,7-dimethoxy-4-(4-morpholinyl)-1-naphthalenyl]-N-phenylacetamide	[no description available]	medium	2	naphthols
N4-(3-chlorophenyl)-6-methyl-N2-(phenylmethyl)pyrimidine-2,4-diamine	[no description available]	medium	2	aralkylamine
2,6-bis(benzimidazol-2-yl)pyridine	[no description available]	medium	2	benzimidazoles
n-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine	[no description available]	medium	2
N-[4-(1-azepanyl)phenyl]-2-chloroacetamide	[no description available]	medium	2	anilide
N-(4-methylphenyl)carbamic acid (cyclopentylideneamino) ester	[no description available]	medium	2	toluenes
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)	[no description available]	medium	2	benzimidazoles
1,4,8-trimethyl-12-quinolino[2,3-b]quinolinamine	[no description available]	medium	2	aminoquinoline
2-furanyl-(4,4,8-trimethyl-1-sulfanylidene-5-dithiolo[3,4-c]quinolinyl)methanone	[no description available]	medium	2	aromatic amide; heteroarene
1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanone	[no description available]	medium	2	quinolines
stk295900	[no description available]	medium	2
6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazole	[no description available]	medium	2	benzimidazoles
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine	[no description available]	medium	2	aromatic ether
N-[2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenyl-2-benzimidazol-3-iumyl]ethenyl]-N-methylaniline	[no description available]	medium	2	benzimidazoles
4-(1-adamantyl)-2-methyl-1,3-thiazole	[no description available]	medium	2	thiazoles
2-amino-6-[4-(6-chloro-2-pyridinyl)-1-piperazinyl]pyridine-3,5-dicarbonitrile	[no description available]	medium	2	piperazines; pyridines
1-(4-fluorophenyl)-3-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)-3-pyrazolyl]urea	[no description available]	medium	2	pyrazoles; ring assembly
2-(4,6,7-Trimethyl-2-quinazolinyl)guanidine	[no description available]	medium	2	quinazolines
polysulfide rubber	[no description available]	medium	2
4-(4-nitrophenyl)-N-prop-2-enyl-1-piperazinecarbothioamide	[no description available]	medium	2	piperazines
zd 6474	[no description available]	medium	2	aromatic ether; organobromine compound; organofluorine compound; piperidines; quinazolines; secondary amine	antineoplastic agent; tyrosine kinase inhibitor
5-bromo-1-(1-oxopropyl)-N,N-dipropyl-2,3-dihydroindole-7-sulfonamide	[no description available]	medium	2	indoles
N-cyclohexyl-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide	[no description available]	medium	2	aromatic amide; heteroarene
2-[(3-ethyl-7-methyl-4-oxo-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide	[no description available]	medium	2	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
trichomonacid	[no description available]	medium	2
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine	[no description available]	medium	2	triazolopyrimidines
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-4-carboxamide	[no description available]	medium	2	isoindoles
penicillin v	[no description available]	medium	1	1,1'-diethyl-2,2'-cyanine; quinolines
hydrocortisone acetate, (11beta)-isomer	[no description available]	medium	2
xib 4035	[no description available]	medium	2
10-hydroxy-3-methyl-8-pentyl-2,4-dihydro-1H-[1]benzopyrano[3,4-c]pyridin-5-one	[no description available]	medium	2	pyridochromene
lumefantrine	[no description available]	medium	2	fluorenes; monochlorobenzenes; secondary alcohol; tertiary amine	antimalarial
suloctidil	[no description available]	medium	1
edatrexate	[no description available]	medium	2	glutamic acid derivative
cgp 71683 a	[no description available]	medium	1
artenimol	[no description available]	medium	1
aee 788	[no description available]	medium	2	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist; trypanocidal drug
tomaymycin	[no description available]	medium	2	tomaymycin
amodiaquine hydrochloride	[no description available]	medium	1
gramicidin a	[no description available]	medium	2
N-methyl-3-[5-(3-phenylpropyl)-1,3,4-oxadiazol-2-yl]-N-(3-thiophenylmethyl)propanamide	[no description available]	medium	2	benzenes
rs 39604	[no description available]	medium	1	hydrochloride	serotonergic antagonist
1-[amino-[(6-methoxy-4-methyl-2-quinazolinyl)amino]methylidene]-3-phenylurea	[no description available]	medium	2	quinazolines
ellipticine	[no description available]	medium	1	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound; polycyclic heteroarene	antineoplastic agent; plant metabolite
plumbagin	[no description available]	medium	1	hydroxy-1,4-naphthoquinone; phenols	anticoagulant; antineoplastic agent; immunological adjuvant; metabolite
cepharanthine	[no description available]	medium	2	bisbenzylisoquinoline alkaloid; isoquinolines
helenalin	[no description available]	medium	1	cyclic ketone; gamma-lactone; organic heterotricyclic compound; secondary alcohol; sesquiterpene lactone	anti-inflammatory agent; antineoplastic agent; metabolite; plant metabolite
tetrahydropalmatine	[no description available]	medium	1	an (S)-7,8,13,14-tetrahydroprotoberberine; berberine alkaloid; organic heterotetracyclic compound	adrenergic agent; dopaminergic antagonist; non-narcotic analgesic
pinostrobin	[no description available]	medium	1	monohydroxyflavanone; monomethoxyflavanone	antidote; plant metabolite
cryptolepine	[no description available]	medium	1	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound	anti-inflammatory agent; antimalarial; antineoplastic agent; cysteine protease inhibitor; plant metabolite
3,4-(dichloro)-5-hydroxy-2(5h)-furanone	[no description available]	medium	1
phomenone	[no description available]	medium	1	sesquiterpenoid
diisocyanoadociane	[no description available]	medium	1
norcoralydine	[no description available]	medium	1	alkaloid
lupeol	[no description available]	medium	2	pentacyclic triterpenoid; secondary alcohol	anti-inflammatory drug; plant metabolite
dentatin	[no description available]	medium	1	coumarins	metabolite
racemosol	[no description available]	medium	1
catechin gallate	[no description available]	medium	1	flavans; gallate ester; polyphenol	metabolite
acacetin	[no description available]	medium	1	dihydroxyflavone; monomethoxyflavone	anticonvulsant; plant metabolite
7,3'-dihydroxy-4'-methoxyisoflavone	[no description available]	medium	1	4'-methoxyisoflavones; 7-hydroxyisoflavones	antioxidant; metabolite
luteolin-7-glucoside	[no description available]	medium	2	beta-D-glucoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antioxidant; plant metabolite
genistein	[no description available]	medium	1	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
budlein a	[no description available]	medium	1	sesquiterpenoid
mangostin	[no description available]	medium	3	aromatic ether; phenols; xanthones	antimicrobial agent; antineoplastic agent; antioxidant; plant metabolite
cerulenin	[no description available]	medium	1	epoxide; monocarboxylic acid amide	antifungal agent; antiinfective agent; antilipemic drug; antimetabolite; antimicrobial agent; fatty acid synthesis inhibitor
clausarin	[no description available]	medium	1
iridal	[no description available]	medium	1
tazettine	[no description available]	medium	9	indole alkaloid fundamental parent; indole alkaloid
4-hydroxylonchocarpin	[no description available]	medium	1
dolastatin 10	[no description available]	medium	1	1,3-thiazoles; tetrapeptide	animal metabolite; antineoplastic agent; apoptosis inducer; marine metabolite; microtubule-destabilising agent
mer nf5003f	[no description available]	medium	1
lepadin f	[no description available]	medium	1
2',3,4,4'-tetrahydroxy-5-prenylchalcone	[no description available]	medium	1
3-epioleanolic acid	[no description available]	medium	1	triterpenoid	metabolite
dehydroabietinol	[no description available]	medium	1	abietane diterpenoid; carbotricyclic compound
neo-kauluamine	[no description available]	medium	1
eurycomanone	[no description available]	medium	1	cyclic ether; delta-lactone; enone; organic heteropentacyclic compound; pentol; quassinoid; secondary alcohol; secondary alpha-hydroxy ketone; tertiary alcohol	antimalarial; antineoplastic agent; metabolite
pycnidione	[no description available]	medium	1
ketoconazole	[no description available]	medium	1	dichlorobenzene; dioxolane; ether; imidazoles; N-acylpiperazine; N-arylpiperazine
amarbellisine	[no description available]	medium	4
dihydrolycorine	[no description available]	medium	2
homolycorine	[no description available]	medium	5
crinine	[no description available]	medium	4	alkaloid
montanine	[no description available]	medium	4
crinamine	[no description available]	medium	4
hippadine	[no description available]	medium	3
anhydrolycorinone	[no description available]	medium	3	phenanthridines
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	[no description available]	medium	1	non-proteinogenic alpha-amino acid
nsc-267703	[no description available]	medium	1	anthracycline
dactinomycin	[no description available]	medium	1	cyclodepsipeptide
amodiaquine	[no description available]	medium	3	aminoquinoline; organochlorine compound; phenols; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; drug allergen; EC 2.1.1.8 (histamine N-methyltransferase) inhibitor; non-steroidal anti-inflammatory drug; prodrug
berberine	[no description available]	medium	1	alkaloid antibiotic; berberine alkaloid; botanical anti-fungal agent; organic heteropentacyclic compound	antilipemic drug; antineoplastic agent; antioxidant; EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor; EC 1.21.3.3 (reticuline oxidase) inhibitor; EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.11.10 (IkappaB kinase) inhibitor; EC 3.1.1.4 (phospholipase A2) inhibitor; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor; EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; geroprotector; hypoglycemic agent; metabolite; potassium channel blocker
clofilium	[no description available]	medium	1	benzenes; organic amino compound
dequalinium	[no description available]	medium	1	quinolinium ion	antifungal agent; antineoplastic agent; antiseptic drug; mitochondrial NADH:ubiquinone reductase inhibitor
nsc-526417	[no description available]	medium	1
gentian violet	[no description available]	medium	1	iminium ion	antibacterial agent; antifungal agent
hexahydrosiladifenidol	[no description available]	medium	1
cycloguanil	[no description available]	medium	1	triazines	antifolate; antiinfective agent; antimalarial; antiparasitic agent; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
triphenyltetrazolium	[no description available]	medium	1	organic cation
berbamine	[no description available]	medium	1	phenylpropanoid
palmatine	[no description available]	medium	1	berberine alkaloid; organic heterotetracyclic compound	plant metabolite
4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine	[no description available]	medium	1
naphthoxybutanolcyclohexylamine	[no description available]	medium	1
staurosporine	[no description available]	medium	2	indolocarbazole alkaloid; organic heterooctacyclic compound	apoptosis inducer; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; geroprotector
propamidine	[no description available]	medium	1	aromatic ether; guanidines; polyether	antimicrobial agent; antiseptic drug
quinocide	[no description available]	medium	1
clobetasone butyrate	[no description available]	medium	1	organic molecular entity
jatrorrhizine	[no description available]	medium	1	alkaloid
LSM-4272	[no description available]	medium	1	beta-carbolines
2,4-diamino-5,6-dihydro-6,6-dimethyl-5-(4'-methoxyphenyl)-s-triazine	[no description available]	medium	1
10-deazaaminopterin	[no description available]	medium	1
benzamil	[no description available]	medium	1	guanidines; pyrazines
imiloxan	[no description available]	medium	1	benzodioxine
epiberberine	[no description available]	medium	1
mensacarcin	[no description available]	medium	1
cephaelin	[no description available]	medium	2	pyridoisoquinoline
wr-142,490	[no description available]	medium	1	[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol	antimalarial
(1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol	[no description available]	medium	1	alkylbenzene
n-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine	[no description available]	medium	1
lch-7749944	[no description available]	medium	1
cgp 71683 a	[no description available]	medium	1	naphthalenes; sulfonic acid derivative
2-(dimethylaminostyryl)-1-ethylpyridinium	[no description available]	medium	1	pyridinium ion
norketotifen	[no description available]	medium	1	organosulfur heterocyclic compound
Geraniin	[no description available]	medium	1	tannin
pancracine	[no description available]	medium	4	isoquinoline alkaloid fundamental parent; isoquinoline alkaloid
oxophenylarsine	[no description available]	medium	1	arsine oxides	antineoplastic agent; apoptosis inducer; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
temozolomide	[no description available]	medium	2	imidazotetrazine; monocarboxylic acid amide; triazene derivative	alkylating agent; antineoplastic agent; prodrug
podophyllotoxin	[no description available]	medium	2	furonaphthodioxole; lignan; organic heterotetracyclic compound	antimitotic; antineoplastic agent; keratolytic drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
paclitaxel	[no description available]	medium	1	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
vincaleukoblastine	[no description available]	medium	1	acetate ester; indole alkaloid fundamental parent; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; immunosuppressive agent; microtubule-destabilising agent; plant metabolite
hamayne	[no description available]	medium	3	alkaloid
pleconaril	[no description available]	medium	2
floxacillin	[no description available]	medium	1	isoquinolines
lycoramine	[no description available]	medium	3	benzazepine
penicillin g	[no description available]	medium	1	penicillin allergen; penicillin	antibacterial drug; drug allergen; epitope
lycorenine	[no description available]	medium	2	alkaloid
sitosterol, (3beta)-isomer	[no description available]	medium	1	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; C29-steroid; phytosterols; stigmastane sterol	anticholesteremic drug; antioxidant; mouse metabolite; plant metabolite; sterol methyltransferase inhibitor
farrerol	[no description available]	medium	1	organic molecular entity	metabolite
sideroxylin	[no description available]	medium	1	dihydroxyflavone; monomethoxyflavone	plant metabolite
lyoniside	[no description available]	medium	1	beta-D-glucoside; monosaccharide derivative; steroid saponin	plant metabolite
tetracycline	[no description available]	medium	1
fluoxetine	[no description available]	medium	1	(trifluoromethyl)benzenes; aromatic ether; secondary amino compound
hydroxychloroquine	[no description available]	medium	2	aminoquinoline; organochlorine compound; primary alcohol; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; dermatologic drug
niclosamide	[no description available]	medium	1	benzamides; C-nitro compound; monochlorobenzenes; salicylanilides; secondary carboxamide	anthelminthic drug; anticoronaviral agent; antiparasitic agent; apoptosis inducer; molluscicide; piscicide; STAT3 inhibitor
prochlorperazine	[no description available]	medium	1	N-alkylpiperazine; N-methylpiperazine; organochlorine compound; phenothiazines	alpha-adrenergic antagonist; antiemetic; cholinergic antagonist; dopamine receptor D2 antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; first generation antipsychotic
salmeterol xinafoate	[no description available]	medium	1	ether; phenols; primary alcohol; secondary alcohol; secondary amino compound
bromocriptine	[no description available]	medium	1	indole alkaloid	antidyskinesia agent; antiparkinson drug; dopamine agonist; hormone antagonist
mefloquine	[no description available]	medium	1	[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol	antimalarial
nelfinavir	[no description available]	medium	2	aryl sulfide; benzamides; organic heterobicyclic compound; phenols; secondary alcohol; tertiary amino compound	antineoplastic agent; HIV protease inhibitor
betulinic acid	[no description available]	medium	2	hydroxy monocarboxylic acid; pentacyclic triterpenoid	anti-HIV agent; anti-inflammatory agent; antimalarial; antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; plant metabolite
baicalin	[no description available]	medium	2	dihydroxyflavone; glucosiduronic acid; glycosyloxyflavone; monosaccharide derivative	antiatherosclerotic agent; antibacterial agent; anticoronaviral agent; antineoplastic agent; antioxidant; cardioprotective agent; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; ferroptosis inhibitor; neuroprotective agent; non-steroidal anti-inflammatory drug; plant metabolite; prodrug
honokiol	[no description available]	medium	2	biphenyls
pacein	[no description available]	medium	1
ezetimibe	[no description available]	medium	1	azetidines; beta-lactam; organofluorine compound	anticholesteremic drug; antilipemic drug; antimetabolite
schizandrin a	[no description available]	medium	1
erlotinib	[no description available]	medium	2	aromatic ether; quinazolines; secondary amino compound; terminal acetylenic compound	antineoplastic agent; epidermal growth factor receptor antagonist; protein kinase inhibitor
naringenin	[no description available]	medium	1	(2S)-flavan-4-one; naringenin	expectorant; plant metabolite
posaconazole	[no description available]	medium	2	aromatic ether; conazole antifungal drug; N-arylpiperazine; organofluorine compound; oxolanes; triazole antifungal drug; triazoles	trypanocidal drug
carbenoxolone	[no description available]	medium	1
citral	[no description available]	medium	1	enal; monoterpenoid; polyprenal	plant metabolite; volatile oil component
lanatoside c	[no description available]	medium	1
curcumin	[no description available]	medium	2	aromatic ether; beta-diketone; diarylheptanoid; enone; polyphenol	anti-inflammatory agent; antifungal agent; antineoplastic agent; biological pigment; contraceptive drug; dye; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; flavouring agent; food colouring; geroprotector; hepatoprotective agent; immunomodulator; iron chelator; ligand; lipoxygenase inhibitor; metabolite; neuroprotective agent; nutraceutical; radical scavenger
hirsutine	[no description available]	medium	1
tolcapone	[no description available]	medium	1	2-nitrophenols; benzophenones; catechols	antiparkinson drug; EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
quercetin	[no description available]	medium	3	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger
quercitrin	[no description available]	medium	1	alpha-L-rhamnoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	antileishmanial agent; antioxidant; EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor; EC 1.1.1.21 (aldehyde reductase) inhibitor; EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
caryophyllene	[no description available]	medium	1	beta-caryophyllene	fragrance; insect attractant; metabolite; non-steroidal anti-inflammatory drug
brefeldin a	[no description available]	medium	1	macrolide antibiotic	Penicillium metabolite
peridinin	[no description available]	medium	1
andrographolide	[no description available]	medium	1	carbobicyclic compound; gamma-lactone; labdane diterpenoid; primary alcohol; secondary alcohol	anti-HIV agent; anti-inflammatory drug; antineoplastic agent; metabolite
su 11248	[no description available]	medium	2	monocarboxylic acid amide; pyrroles	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; immunomodulator; neuroprotective agent; vascular endothelial growth factor receptor antagonist
cyclo(leucyl-prolyl)	[no description available]	medium	1	dipeptide; homodetic cyclic peptide; pyrrolopyrazine	bacterial metabolite; marine metabolite
osu 03012	[no description available]	medium	1	antibiotic antifungal drug; aromatic amide; glycine derivative; organofluorine compound; phenanthrenes; pyrazoles	antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
lactimidomycin	[no description available]	medium	1	macrolide
sofosbuvir	[no description available]	medium	2	isopropyl ester; L-alanyl ester; nucleotide conjugate; organofluorine compound; phosphoramidate ester	antiviral drug; hepatitis C protease inhibitor; prodrug
tatanan a	[no description available]	medium	1
niacin	[no description available]	medium	1	pyridine alkaloid; pyridinemonocarboxylic acid; vitamin B3	antidote; antilipemic drug; EC 3.5.1.19 (nicotinamidase) inhibitor; Escherichia coli metabolite; human urinary metabolite; metabolite; mouse metabolite; plant metabolite; vasodilator agent
miltefosine	[no description available]	medium	2	phosphocholines; phospholipid	anti-inflammatory agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antiprotozoal drug; apoptosis inducer; immunomodulator; protein kinase inhibitor
protopine	[no description available]	medium	1	dibenzazecine alkaloid	plant metabolite
melarsoprol	[no description available]	medium	1	triazines
ornidazole	[no description available]	medium	1	C-nitro compound; imidazoles; organochlorine compound; secondary alcohol	antiamoebic agent; antibacterial drug; antiinfective agent; antiprotozoal drug; antitrichomonal drug; epitope
benzonidazole	[no description available]	medium	1	C-nitro compound; imidazoles; monocarboxylic acid amide	antiprotozoal drug
pretazettine	[no description available]	medium	2	alkaloid
hippeastrine	[no description available]	medium	3	delta-lactone; indole alkaloid; organic heteropentacyclic compound; secondary alcohol	antineoplastic agent; metabolite
camostat	[no description available]	medium	2	benzoate ester; carboxylic ester; diester; guanidines; tertiary carboxamide	anti-inflammatory agent; anticoronaviral agent; antifibrinolytic drug; antihypertensive agent; antineoplastic agent; antiviral agent; serine protease inhibitor
nafamostat	[no description available]	medium	2	benzoic acids; guanidines
phenazopyridine	[no description available]	medium	2	diaminopyridine; monoazo compound	anticoronaviral agent; carcinogenic agent; local anaesthetic; non-narcotic analgesic
reserpine	[no description available]	medium	1	alkaloid ester; methyl ester; yohimban alkaloid	adrenergic uptake inhibitor; antihypertensive agent; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; first generation antipsychotic; plant metabolite; xenobiotic
glycyrrhizic acid	[no description available]	medium	1	enone; glucosiduronic acid; pentacyclic triterpenoid; tricarboxylic acid; triterpenoid saponin	EC 3.4.21.5 (thrombin) inhibitor; plant metabolite
nitazoxanide	[no description available]	medium	2	benzamides; carboxylic ester
epigallocatechin gallate	[no description available]	medium	2	flavans; gallate ester; polyphenol	antineoplastic agent; antioxidant; apoptosis inducer; geroprotector; Hsp90 inhibitor; neuroprotective agent; plant metabolite
hesperetin	[no description available]	medium	1	3'-hydroxyflavanones; 4'-methoxyflavanones; monomethoxyflavanone; trihydroxyflavanone	antineoplastic agent; antioxidant; plant metabolite
pulsatilla saponin a	[no description available]	medium	1	disaccharide derivative; hydroxy monocarboxylic acid; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
lopinavir	[no description available]	medium	1	amphetamines; dicarboxylic acid diamide	anticoronaviral agent; antiviral drug; HIV protease inhibitor
pectolinarin	[no description available]	medium	2	dimethoxyflavone; disaccharide derivative; glycosyloxyflavone; monohydroxyflavanone; rutinoside	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; plant metabolite
(-)-gallocatechin gallate	[no description available]	medium	1	catechin; gallate ester; polyphenol	antineoplastic agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; human xenobiotic metabolite; plant metabolite
mycophenolic acid	[no description available]	medium	1	2-benzofurans; gamma-lactone; monocarboxylic acid; phenols	anticoronaviral agent; antimicrobial agent; antineoplastic agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; environmental contaminant; immunosuppressive agent; mycotoxin; Penicillium metabolite; xenobiotic
favipiravir	[no description available]	medium	2	hydroxypyrazine; organofluorine compound; primary carboxamide	anticoronaviral agent; antiviral drug; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
hirsutanone	[no description available]	medium	2	diarylheptanoid
valinomycin	[no description available]	medium	1	cyclodepsipeptide; macrocycle	antimicrobial agent; antiviral agent; bacterial metabolite; potassium ionophore
herbacetin	[no description available]	medium	2	7-hydroxyflavonol; pentahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antilipemic drug; antineoplastic agent; apoptosis inducer; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; plant metabolite
mycophenolate mofetil	[no description available]	medium	2	carboxylic ester; ether; gamma-lactone; phenols; tertiary amino compound	anticoronaviral agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; immunosuppressive agent; prodrug
isobavachalcone	[no description available]	medium	1	chalcones; polyphenol	antibacterial agent; metabolite; platelet aggregation inhibitor
psoralidin	[no description available]	medium	1	coumestans; delta-lactone; polyphenol	estrogen receptor agonist; plant metabolite
rhoifolin	[no description available]	medium	2	dihydroxyflavone; glycosyloxyflavone; neohesperidoside	metabolite
neobavaisoflavone	[no description available]	medium	1	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; plant metabolite; platelet aggregation inhibitor
escin ia	[no description available]	medium	1
papyriflavonol a	[no description available]	medium	1	3'-hydroxyflavonoid; flavonols; pentahydroxyflavone	EC 1.14.18.1 (tyrosinase) inhibitor; EC 3.1.1.4 (phospholipase A2) inhibitor; metabolite
monensin	[no description available]	medium	1
pyrvinium pamoate	[no description available]	medium	1	naphthoic acid	anticoronaviral agent
bananin	[no description available]	medium	1
s 8932	[no description available]	medium	4	aromatic amine; C-nucleoside; carboxylic ester; nitrile; phosphoramidate ester; pyrrolotriazine	anticoronaviral agent; antiviral drug; prodrug
penciclovir	[no description available]	medium	2	2-aminopurines; propane-1,3-diols	antiviral drug
emodin	[no description available]	medium	1	trihydroxyanthraquinone	antineoplastic agent; laxative; plant metabolite; tyrosine kinase inhibitor
cryptotanshinone	[no description available]	medium	1	abietane diterpenoid	anticoronaviral agent
Ganodermanontriol	[no description available]	medium	1	triterpenoid	metabolite
ellagic acid	[no description available]	medium	1	catechols; cyclic ketone; lactone; organic heterotetracyclic compound; polyphenol	antioxidant; EC 1.14.18.1 (tyrosinase) inhibitor; EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor; EC 2.4.1.1 (glycogen phosphorylase) inhibitor; EC 2.5.1.18 (glutathione transferase) inhibitor; EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor; EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor; EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; food additive; fungal metabolite; geroprotector; plant metabolite; skin lightening agent
galidesivir	[no description available]	medium	2
stavudine	[no description available]	medium	2	dihydrofuran; nucleoside analogue; organic molecular entity	antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
2'-c-methylcytidine	[no description available]	medium	2
podocarpusflavone a	[no description available]	medium	1	flavonoid oligomer
22,23-dihydroavermectin b(1)a	[no description available]	medium	1	macrocyclic lactone; spiroketal
entrectinib	[no description available]	medium	1	benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide	antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
valganciclovir	[no description available]	medium	1	L-valyl ester; purines	antiviral drug; prodrug
aminolevulinic acid	[no description available]	medium	1	4-oxo monocarboxylic acid; amino acid zwitterion; delta-amino acid	antineoplastic agent; dermatologic drug; Escherichia coli metabolite; human metabolite; mouse metabolite; photosensitizing agent; plant metabolite; prodrug; Saccharomyces cerevisiae metabolite
coumarin	[no description available]	medium	1	coumarins	fluorescent dye; human metabolite; plant metabolite
salicylic acid	[no description available]	medium	1	monohydroxybenzoic acid	algal metabolite; antifungal agent; antiinfective agent; EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor; keratolytic drug; plant hormone; plant metabolite
thioctic acid	[no description available]	medium	1	dithiolanes; heterocyclic fatty acid; thia fatty acid	fundamental metabolite; geroprotector
picolinic acid	[no description available]	medium	1	pyridinemonocarboxylic acid	human metabolite; MALDI matrix material
thiamine	[no description available]	medium	1	primary alcohol; vitamin B1	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
3-aminobenzamide	[no description available]	medium	1	benzamides; substituted aniline	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
4-(2-aminoethyl)benzenesulfonylfluoride	[no description available]	medium	1
phenytoin	[no description available]	medium	1	imidazolidine-2,4-dione	anticonvulsant; drug allergen; sodium channel blocker; teratogenic agent
acetazolamide	[no description available]	medium	1	monocarboxylic acid amide; sulfonamide; thiadiazoles	anticonvulsant; diuretic; EC 4.2.1.1 (carbonic anhydrase) inhibitor
alprenolol	[no description available]	medium	1	secondary alcohol; secondary amino compound	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; sympatholytic agent
amantadine	[no description available]	medium	1	adamantanes; primary aliphatic amine	analgesic; antiparkinson drug; antiviral drug; dopaminergic agent; NMDA receptor antagonist; non-narcotic analgesic
2-aminothiazole	[no description available]	medium	1	1,3-thiazoles; primary amino compound
aspirin	[no description available]	medium	1	benzoic acids; phenyl acetates; salicylates	anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent
baclofen	[no description available]	medium	1	amino acid zwitterion; gamma-amino acid; monocarboxylic acid; monochlorobenzenes; primary amino compound	central nervous system depressant; GABA agonist; muscle relaxant
benzamide	[no description available]	medium	1	benzamides
camphor, (+-)-isomer	[no description available]	medium	1	bornane monoterpenoid; cyclic monoterpene ketone	plant metabolite
candesartan	[no description available]	medium	1	benzimidazolecarboxylic acid; biphenylyltetrazole	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
cetylpyridinium	[no description available]	medium	1	pyridinium ion
chloroxylenol	[no description available]	medium	1	monochlorobenzenes; phenols	antiseptic drug; disinfectant; molluscicide
chlorpromazine	[no description available]	medium	1	organochlorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; phenothiazine antipsychotic drug
ciprofibrate	[no description available]	medium	1	cyclopropanes; monocarboxylic acid; organochlorine compound	antilipemic drug
clomipramine	[no description available]	medium	1	dibenzoazepine	anticoronaviral agent; antidepressant; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; serotonergic antagonist; serotonergic drug; serotonin uptake inhibitor
danthron	[no description available]	medium	1	dihydroxyanthraquinone	apoptosis inducer; plant metabolite
deferiprone	[no description available]	medium	1	4-pyridones	iron chelator; protective agent
dipyridamole	[no description available]	medium	1	piperidines; pyrimidopyrimidine; tertiary amino compound; tetrol	adenosine phosphodiesterase inhibitor; EC 3.5.4.4 (adenosine deaminase) inhibitor; platelet aggregation inhibitor; vasodilator agent
disulfiram	[no description available]	medium	1	organic disulfide; organosulfur acaricide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 3.1.1.1 (carboxylesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; ferroptosis inducer; fungicide; NF-kappaB inhibitor
valproic acid	[no description available]	medium	1	branched-chain fatty acid; branched-chain saturated fatty acid	anticonvulsant; antimanic drug; EC 3.5.1.98 (histone deacetylase) inhibitor; GABA agent; neuroprotective agent; psychotropic drug; teratogenic agent
doxazosin	[no description available]	medium	1	aromatic amine; benzodioxine; monocarboxylic acid amide; N-acylpiperazine; N-arylpiperazine; quinazolines	alpha-adrenergic antagonist; antihyperplasia drug; antihypertensive agent; antineoplastic agent; vasodilator agent
ebselen	[no description available]	medium	1	benzoselenazole	anti-inflammatory drug; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 3.5.4.1 (cytosine deaminase) inhibitor; EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor; enzyme mimic; ferroptosis inhibitor; genotoxin; hepatoprotective agent; neuroprotective agent; radical scavenger
etidronate	[no description available]	medium	1	1,1-bis(phosphonic acid)	antineoplastic agent; bone density conservation agent; chelator
2-hexyloxybenzamide	[no description available]	medium	1	aromatic ether; benzamides	antifungal agent
brl 42810	[no description available]	medium	1	2-aminopurines; acetate ester	antiviral drug; prodrug
fluphenazine	[no description available]	medium	1	N-alkylpiperazine; organofluorine compound; phenothiazines	anticoronaviral agent; dopaminergic antagonist; phenothiazine antipsychotic drug
fluorouracil	[no description available]	medium	1	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
gabexate	[no description available]	medium	1	benzoate ester
glutaral	[no description available]	medium	1	dialdehyde	cross-linking reagent; disinfectant; fixative
fasudil	[no description available]	medium	1	isoquinolines; N-sulfonyldiazepane	antihypertensive agent; calcium channel blocker; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; geroprotector; neuroprotective agent; nootropic agent; vasodilator agent
haloperidol	[no description available]	medium	1	aromatic ketone; hydroxypiperidine; monochlorobenzenes; organofluorine compound; tertiary alcohol	antidyskinesia agent; antiemetic; dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist
hexylresorcinol	[no description available]	medium	1	resorcinols
beta-thujaplicin	[no description available]	medium	1	cyclic ketone; enol; monoterpenoid	antibacterial agent; antifungal agent; antineoplastic agent; antiplasmodial drug; plant metabolite
hycanthone	[no description available]	medium	1	thioxanthenes	mutagen; schistosomicide drug
hydrochlorothiazide	[no description available]	medium	1	benzothiadiazine; organochlorine compound; sulfonamide	antihypertensive agent; diuretic; environmental contaminant; xenobiotic
hydroxyurea	[no description available]	medium	1	one-carbon compound; ureas	antimetabolite; antimitotic; antineoplastic agent; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; genotoxin; immunomodulator; radical scavenger; teratogenic agent
ibuprofen	[no description available]	medium	1	monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; radical scavenger; xenobiotic
indomethacin	[no description available]	medium	1	aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole	analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic
avapro	[no description available]	medium	1	azaspiro compound; biphenylyltetrazole	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
itraconazole	[no description available]	medium	1	piperazines
kojic acid	[no description available]	medium	1	4-pyranones; enol; primary alcohol	Aspergillus metabolite; EC 1.10.3.1 (catechol oxidase) inhibitor; EC 1.10.3.2 (laccase) inhibitor; EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor; EC 1.14.18.1 (tyrosinase) inhibitor; EC 1.4.3.3 (D-amino-acid oxidase) inhibitor; NF-kappaB inhibitor; skin lightening agent
lapachol	[no description available]	medium	1
loperamide	[no description available]	medium	1	monocarboxylic acid amide; monochlorobenzenes; piperidines; tertiary alcohol	anticoronaviral agent; antidiarrhoeal drug; mu-opioid receptor agonist
loratadine	[no description available]	medium	1	benzocycloheptapyridine; ethyl ester; N-acylpiperidine; organochlorine compound; tertiary carboxamide	anti-allergic agent; cholinergic antagonist; geroprotector; H1-receptor antagonist
losartan	[no description available]	medium	1	biphenylyltetrazole; imidazoles	angiotensin receptor antagonist; anti-arrhythmia drug; antihypertensive agent; endothelin receptor antagonist
4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamide	[no description available]	medium	1	benzamides; hydroxamic acid; secondary carboxamide; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
mafenide	[no description available]	medium	1	aromatic amine
methazolamide	[no description available]	medium	1	sulfonamide; thiadiazoles
methocarbamol	[no description available]	medium	1	aromatic ether; carbamate ester; secondary alcohol
mitoxantrone	[no description available]	medium	1	dihydroxyanthraquinone	analgesic; antineoplastic agent
entinostat	[no description available]	medium	1	benzamides; carbamate ester; primary amino compound; pyridines; substituted aniline	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
ethylmaleimide	[no description available]	medium	1	maleimides	anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor
nabumetone	[no description available]	medium	1	methoxynaphthalene; methyl ketone	cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug
nevirapine	[no description available]	medium	1	cyclopropanes; dipyridodiazepine	antiviral drug; HIV-1 reverse transcriptase inhibitor
omeprazole	[no description available]	medium	1	aromatic ether; benzimidazoles; pyridines; sulfoxide
osalmide	[no description available]	medium	1	organic molecular entity
oxethazaine	[no description available]	medium	1	amino acid amide
palmidrol	[no description available]	medium	1	endocannabinoid; N-(long-chain-acyl)ethanolamine; N-(saturated fatty acyl)ethanolamine	anti-inflammatory drug; anticonvulsant; antihypertensive agent; neuroprotective agent
papaverine	[no description available]	medium	1	benzylisoquinoline alkaloid; dimethoxybenzene; isoquinolines	antispasmodic drug; vasodilator agent
pentoxifylline	[no description available]	medium	1	oxopurine
perhexiline	[no description available]	medium	1	piperidines	cardiovascular drug
4-phenylbutyric acid	[no description available]	medium	1	monocarboxylic acid	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor; prodrug
phenylmethylsulfonyl fluoride	[no description available]	medium	1	acyl fluoride	serine proteinase inhibitor
pimobendan	[no description available]	medium	1	benzimidazoles; pyridazinone	cardiotonic drug; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
pj-34	[no description available]	medium	1	phenanthridines; secondary carboxamide; tertiary amino compound	angiogenesis inhibitor; anti-inflammatory agent; antiatherosclerotic agent; antineoplastic agent; apoptosis inducer; cardioprotective agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; neuroprotective agent
praziquantel	[no description available]	medium	1	isoquinolines
probenecid	[no description available]	medium	1	benzoic acids; sulfonamide	uricosuric drug
probucol	[no description available]	medium	1	dithioketal; polyphenol	anti-inflammatory drug; anticholesteremic drug; antilipemic drug; antioxidant; cardiovascular drug
promazine	[no description available]	medium	1	phenothiazines; tertiary amine	antiemetic; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; H1-receptor antagonist; muscarinic antagonist; phenothiazine antipsychotic drug; serotonergic antagonist
promethazine	[no description available]	medium	1	phenothiazines; tertiary amine	anti-allergic agent; anticoronaviral agent; antiemetic; antipruritic drug; H1-receptor antagonist; local anaesthetic; sedative
propranolol	[no description available]	medium	1	naphthalenes; propanolamine; secondary amine	anti-arrhythmia drug; antihypertensive agent; anxiolytic drug; beta-adrenergic antagonist; environmental contaminant; human blood serum metabolite; vasodilator agent; xenobiotic
rimantadine	[no description available]	medium	1	alkylamine
rolipram	[no description available]	medium	1	pyrrolidin-2-ones	antidepressant; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
sebacic acid	[no description available]	medium	1	alpha,omega-dicarboxylic acid; dicarboxylic fatty acid	human metabolite; plant metabolite
fenofibrate	[no description available]	medium	1	benzochromenone; delta-lactone; naphtho-alpha-pyrone	platelet aggregation inhibitor; Sir2 inhibitor
imatinib	[no description available]	medium	1	aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines	antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
suprofen	[no description available]	medium	1	aromatic ketone; monocarboxylic acid; thiophenes	antirheumatic drug; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug
thalidomide	[no description available]	medium	1	phthalimides; piperidones
ticlopidine	[no description available]	medium	1	monochlorobenzenes; thienopyridine	anticoagulant; fibrin modulating drug; hematologic agent; P2Y12 receptor antagonist; platelet aggregation inhibitor
triamterene	[no description available]	medium	1	pteridines	diuretic; sodium channel blocker
trifluoperazine	[no description available]	medium	1	N-alkylpiperazine; N-methylpiperazine; organofluorine compound; phenothiazines	antiemetic; calmodulin antagonist; dopaminergic antagonist; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor; EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor; phenothiazine antipsychotic drug
triflupromazine	[no description available]	medium	1	organofluorine compound; phenothiazines; tertiary amine	anticoronaviral agent; antiemetic; dopaminergic antagonist; first generation antipsychotic
trigonelline	[no description available]	medium	1	alkaloid; iminium betaine	food component; human urinary metabolite; plant metabolite
trimethobenzamide	[no description available]	medium	1	benzamides; tertiary amino compound	antiemetic
trimethoprim	[no description available]	medium	1	aminopyrimidine; methoxybenzenes	antibacterial drug; diuretic; drug allergen; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; environmental contaminant; xenobiotic
tyrphostin a9	[no description available]	medium	1	alkylbenzene	geroprotector
delavirdine	[no description available]	medium	1	aminopyridine; indolecarboxamide; N-acylpiperazine; sulfonamide	antiviral drug; HIV-1 reverse transcriptase inhibitor
vesnarinone	[no description available]	medium	1	organic molecular entity
idoxuridine	[no description available]	medium	1	organoiodine compound; pyrimidine 2'-deoxyribonucleoside	antiviral drug; DNA synthesis inhibitor
chloramphenicol	[no description available]	medium	1	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor
lysine	[no description available]	medium	1	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
phenylethyl alcohol	[no description available]	medium	1	benzenes; primary alcohol	Aspergillus metabolite; fragrance; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite
zoxazolamine	[no description available]	medium	1	benzoxazole
ficusin	[no description available]	medium	1	psoralens	plant metabolite
tubercidin	[no description available]	medium	2	antibiotic antifungal agent; N-glycosylpyrrolopyrimidine; ribonucleoside	antimetabolite; antineoplastic agent; bacterial metabolite
trifluridine	[no description available]	medium	1	nucleoside analogue; organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; EC 2.1.1.45 (thymidylate synthase) inhibitor
9,10-anthraquinone	[no description available]	medium	1	anthraquinone
salicylanilide	[no description available]	medium	1	benzanilide fungicide; salicylamides; salicylanilides
gramine	[no description available]	medium	1	aminoalkylindole; indole alkaloid; tertiary amino compound	antibacterial agent; antiviral agent; plant metabolite; serotonergic antagonist
aminacrine	[no description available]	medium	1	aminoacridines; primary amino compound	acid-base indicator; antiinfective agent; antiseptic drug; fluorescent dye; MALDI matrix material; mutagen
methyl gallate	[no description available]	medium	1	gallate ester	anti-inflammatory agent; antioxidant; plant metabolite
monobenzone	[no description available]	medium	1	benzyl ether	allergen; dermatologic drug; melanin synthesis inhibitor
ditiocarb	[no description available]	medium	1	dithiocarbamic acids	chelator; copper chelator
catechin	[no description available]	medium	1	catechin	antioxidant; plant metabolite
azacitidine	[no description available]	medium	1	N-glycosyl-1,3,5-triazine; nucleoside analogue	antineoplastic agent
lucanthone	[no description available]	medium	1	thioxanthenes	adjuvant; antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; mutagen; photosensitizing agent; prodrug; schistosomicide drug
aloe emodin	[no description available]	medium	1	aromatic primary alcohol; dihydroxyanthraquinone	antineoplastic agent; plant metabolite
chrysophanic acid	[no description available]	medium	1	dihydroxyanthraquinone	anti-inflammatory agent; antiviral agent; plant metabolite
osthol	[no description available]	medium	1	botanical anti-fungal agent; coumarins	metabolite
flavanone	[no description available]	medium	1	flavanones
phloretic acid	[no description available]	medium	1	hydroxy monocarboxylic acid	plant metabolite
oleanolic acid	[no description available]	medium	1	hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
angelicin	[no description available]	medium	1	furanocoumarin
diperodon	[no description available]	medium	1	carbamate ester
megestrol acetate	[no description available]	medium	1	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; steroid ester	antineoplastic agent; appetite enhancer; contraceptive drug; progestin; synthetic oral contraceptive
acetylcysteine	[no description available]	medium	2	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
hydroxychloroquine sulfate	[no description available]	medium	1
ethambutol	[no description available]	medium	1	ethanolamines; ethylenediamine derivative	antitubercular agent; environmental contaminant; xenobiotic
metformin hydrochloride	[no description available]	medium	1	hydrochloride	environmental contaminant; hypoglycemic agent; xenobiotic
antimycin a	[no description available]	medium	1	benzamides; formamides; macrodiolide; phenols	antifungal agent; mitochondrial respiratory-chain inhibitor; piscicide
5,5'-dimethyl-2,2'-bipyridyl	[no description available]	medium	1	bipyridines
dichlorobenzyl alcohol	[no description available]	medium	1	benzyl alcohols; dichlorobenzene	antiseptic drug
dideoxyadenosine	[no description available]	medium	1	adenosines; purine 2',3'-dideoxyribonucleoside	EC 3.5.4.4 (adenosine deaminase) inhibitor; EC 4.6.1.1 (adenylate cyclase) inhibitor
vidarabine	[no description available]	medium	1	beta-D-arabinoside; purine nucleoside	antineoplastic agent; bacterial metabolite; nucleoside antibiotic
3-deazaadenosine	[no description available]	medium	1
zalcitabine	[no description available]	medium	1	pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor
ancitabine	[no description available]	medium	1	diol; organic heterotricyclic compound	antimetabolite; antineoplastic agent; prodrug
chloropyramine	[no description available]	medium	1	aminopyridine
levamisole	[no description available]	medium	1	6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole	antinematodal drug; antirheumatic drug; EC 3.1.3.1 (alkaline phosphatase) inhibitor; immunological adjuvant; immunomodulator
n'-nitrosonornicotine	[no description available]	medium	1	pyridines; pyrrolidines
daunorubicin	[no description available]	medium	1	aminoglycoside antibiotic; anthracycline; p-quinones; tetracenequinones	antineoplastic agent; bacterial metabolite
zidovudine	[no description available]	medium	1	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor
pyridoxal phosphate	[no description available]	medium	1	pyridinecarbaldehyde
captopril	[no description available]	medium	1	alkanethiol; L-proline derivative; N-acylpyrrolidine; pyrrolidinemonocarboxylic acid	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
oltipraz	[no description available]	medium	1	1,2-dithiole; pyrazines	angiogenesis modulating agent; antimutagen; antineoplastic agent; antioxidant; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor; neurotoxin; protective agent; schistosomicide drug
fiacitabine	[no description available]	medium	1
ranolazine	[no description available]	medium	1	aromatic amide; monocarboxylic acid amide; monomethoxybenzene; N-alkylpiperazine; secondary alcohol
brequinar	[no description available]	medium	1	biphenyls; monocarboxylic acid; monofluorobenzenes; quinolinemonocarboxylic acid	anticoronaviral agent; antimetabolite; antineoplastic agent; antiviral agent; EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor; immunosuppressive agent; pyrimidine synthesis inhibitor
imiquimod	[no description available]	medium	1	imidazoquinoline	antineoplastic agent; interferon inducer
adefovir	[no description available]	medium	1	6-aminopurines; ether; phosphonic acids	antiviral drug; DNA synthesis inhibitor; drug metabolite; HIV-1 reverse transcriptase inhibitor; nephrotoxic agent
cidofovir anhydrous	[no description available]	medium	1	phosphonic acids; pyrimidone	anti-HIV agent; antineoplastic agent; antiviral drug; photosensitizing agent
celgosivir	[no description available]	medium	1
gemcitabine	[no description available]	medium	2	organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; environmental contaminant; immunosuppressive agent; photosensitizing agent; prodrug; radiosensitizing agent; xenobiotic
lamivudine	[no description available]	medium	1	monothioacetal; nucleoside analogue; oxacycle; primary alcohol	allergen; anti-HBV agent; antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor; HIV-1 reverse transcriptase inhibitor; prodrug
valsartan	[no description available]	medium	1	biphenylyltetrazole; monocarboxylic acid amide; monocarboxylic acid	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
zanamivir	[no description available]	medium	1	guanidines	antiviral agent; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
adefovir dipivoxil	[no description available]	medium	1	6-aminopurines; carbonate ester; ether; organic phosphonate	antiviral drug; DNA synthesis inhibitor; HIV-1 reverse transcriptase inhibitor; nephrotoxic agent; prodrug
emtricitabine	[no description available]	medium	1	monothioacetal; nucleoside analogue; organofluorine compound; pyrimidone	antiviral drug; HIV-1 reverse transcriptase inhibitor
octyl gallate	[no description available]	medium	1	gallate ester	food antioxidant; hypoglycemic agent; plant metabolite
efavirenz	[no description available]	medium	1	acetylenic compound; benzoxazine; cyclopropanes; organochlorine compound; organofluorine compound	antiviral drug; HIV-1 reverse transcriptase inhibitor
arctigenin	[no description available]	medium	1	lignan
plerixafor	[no description available]	medium	1	azacycloalkane; azamacrocycle; benzenes; crown amine; secondary amino compound; tertiary amino compound	anti-HIV agent; antineoplastic agent; C-X-C chemokine receptor type 4 antagonist; immunological adjuvant
amprenavir	[no description available]	medium	1	carbamate ester; sulfonamide; tetrahydrofuryl ester	antiviral drug; HIV protease inhibitor
oseltamivir	[no description available]	medium	1	acetamides; amino acid ester; cyclohexenecarboxylate ester; primary amino compound	antiviral drug; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; environmental contaminant; prodrug; xenobiotic
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose	[no description available]	medium	1	gallate ester; galloyl beta-D-glucose	anti-inflammatory agent; antineoplastic agent; geroprotector; hepatoprotective agent; plant metabolite; radiation protective agent; radical scavenger
cephalotaxine	[no description available]	medium	1	benzazepine alkaloid fundamental parent; benzazepine alkaloid; cyclic acetal; enol ether; organic heteropentacyclic compound; secondary alcohol; tertiary amino compound
desipramine hydrochloride	[no description available]	medium	1	hydrochloride	drug allergen
aloxistatin	[no description available]	medium	1	epoxide; ethyl ester; L-leucine derivative; monocarboxylic acid amide	anticoronaviral agent; cathepsin B inhibitor
propazole	[no description available]	medium	1	benzimidazoles
prulifloxacin	[no description available]	medium	1	fluoroquinolone antibiotic; quinolone antibiotic
telmisartan	[no description available]	medium	1	benzimidazoles; biphenyls; carboxybiphenyl	angiotensin receptor antagonist; antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; environmental contaminant; xenobiotic
bergenin	[no description available]	medium	1	trihydroxybenzoic acid	metabolite
zoledronic acid	[no description available]	medium	1	1,1-bis(phosphonic acid); imidazoles	bone density conservation agent
artemisinin	[no description available]	medium	1	organic peroxide; sesquiterpene lactone	antimalarial; plant metabolite
brinzolamide	[no description available]	medium	1	sulfonamide; thienothiazine	antiglaucoma drug; EC 4.2.1.1 (carbonic anhydrase) inhibitor
dipropylacetamide	[no description available]	medium	1	fatty amide	geroprotector; metabolite; teratogenic agent
oxprenolol hydrochloride	[no description available]	medium	1
opipramol hydrochloride	[no description available]	medium	1
moroxydine	[no description available]	medium	1	biguanides
thioxolone	[no description available]	medium	1	benzoxathiole	antiseborrheic
nobiletin	[no description available]	medium	1	methoxyflavone	antineoplastic agent; plant metabolite
leupeptin	[no description available]	medium	1	aldehyde; tripeptide	bacterial metabolite; calpain inhibitor; cathepsin B inhibitor; EC 3.4.21.4 (trypsin) inhibitor; serine protease inhibitor
tetrandrine	[no description available]	medium	1	bisbenzylisoquinoline alkaloid; isoquinolines
calpeptin	[no description available]	medium	1	amino acid amide
fangchinoline	[no description available]	medium	1	aromatic ether; bisbenzylisoquinoline alkaloid; macrocycle	anti-HIV-1 agent; anti-inflammatory agent; antineoplastic agent; antioxidant; neuroprotective agent; plant metabolite
maslinic acid	[no description available]	medium	1	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; plant metabolite
atovaquone	[no description available]	medium	1	hydroxy-1,2-naphthoquinone
loganin	[no description available]	medium	1	beta-D-glucoside; cyclopentapyran; enoate ester; iridoid monoterpenoid; methyl ester; monosaccharide derivative; secondary alcohol	anti-inflammatory agent; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; EC 3.4.23.46 (memapsin 2) inhibitor; neuroprotective agent; plant metabolite
moexipril	[no description available]	medium	1	peptide
aucubin	[no description available]	medium	1	organic molecular entity	metabolite
catalpol	[no description available]	medium	1	organic molecular entity	metabolite
lekoptin	[no description available]	medium	1	2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
n-methyladenosine	[no description available]	medium	1	methyladenosine
sivelestat	[no description available]	medium	1	N-acylglycine; pivalate ester
pyronaridine	[no description available]	medium	1	aminoquinoline
geniposide	[no description available]	medium	1	terpene glycoside
daidzin	[no description available]	medium	1	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative	plant metabolite
sophocarpine	[no description available]	medium	1
marimastat	[no description available]	medium	1	hydroxamic acid; secondary carboxamide	antineoplastic agent; matrix metalloproteinase inhibitor
elacridar	[no description available]	medium	1
celastrol	[no description available]	medium	1	monocarboxylic acid; pentacyclic triterpenoid	anti-inflammatory drug; antineoplastic agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; Hsp90 inhibitor; metabolite
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine	[no description available]	medium	1	leucine derivative
vadimezan	[no description available]	medium	1	monocarboxylic acid; xanthones	antineoplastic agent
e 64	[no description available]	medium	1	dicarboxylic acid monoamide; epoxy monocarboxylic acid; guanidines; L-leucine derivative; zwitterion	antimalarial; antiparasitic agent; protease inhibitor
umifenovir	[no description available]	medium	1	indolyl carboxylic acid
safinamide	[no description available]	medium	1	amino acid amide
ilomastat	[no description available]	medium	1	hydroxamic acid; L-tryptophan derivative; N-acyl-amino acid	anti-inflammatory agent; antibacterial agent; antineoplastic agent; EC 3.4.24.24 (gelatinase A) inhibitor; neuroprotective agent
atazanavir	[no description available]	medium	1	carbohydrazide	antiviral drug; HIV protease inhibitor
vx 497	[no description available]	medium	1
bcx 1812	[no description available]	medium	1	3-hydroxy monocarboxylic acid; acetamides; cyclopentanols; guanidines	antiviral drug; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
naproxen	[no description available]	medium	1	methoxynaphthalene; monocarboxylic acid	antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; gout suppressant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
olmesartan	[no description available]	medium	1	biphenylyltetrazole	angiotensin receptor antagonist; antihypertensive agent
telbivudine	[no description available]	medium	1	pyrimidine 2'-deoxyribonucleoside	antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
resiquimod	[no description available]	medium	1	imidazoquinoline
tanshinone ii a	[no description available]	medium	1	abietane diterpenoid
anacardic acid	[no description available]	medium	1	hydroxy monocarboxylic acid; hydroxybenzoic acid	anti-inflammatory agent; antibacterial agent; anticoronaviral agent; apoptosis inducer; EC 2.3.1.48 (histone acetyltransferase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; neuroprotective agent; plant metabolite
migalastat	[no description available]	medium	1	piperidines
limonin	[no description available]	medium	1	epoxide; furans; hexacyclic triterpenoid; lactone; limonoid; organic heterohexacyclic compound	inhibitor; metabolite; volatile oil component
scutellarin	[no description available]	medium	1	glucosiduronic acid; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antineoplastic agent; proteasome inhibitor
etravirine	[no description available]	medium	1	aminopyrimidine; aromatic ether; dinitrile; organobromine compound	antiviral agent; HIV-1 reverse transcriptase inhibitor
chelidonine	[no description available]	medium	1	alkaloid antibiotic; alkaloid fundamental parent; benzophenanthridine alkaloid
4-n-butylresorcinol	[no description available]	medium	1	resorcinols
darunavir	[no description available]	medium	1	carbamate ester; furofuran; sulfonamide	antiviral drug; HIV protease inhibitor
dapivirine	[no description available]	medium	1
nsc 74859	[no description available]	medium	1	amidobenzoic acid; monohydroxybenzoic acid; tosylate ester	STAT3 inhibitor
berbamine	[no description available]	medium	1	bisbenzylisoquinoline alkaloid; isoquinolines
u-104	[no description available]	medium	1
7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]-1-benzopyran-4-one	[no description available]	medium	1	glycoside
bortezomib	[no description available]	medium	2	amino acid amide; L-phenylalanine derivative; pyrazines	antineoplastic agent; antiprotozoal drug; protease inhibitor; proteasome inhibitor
ritonavir	[no description available]	medium	1	1,3-thiazoles; carbamate ester; carboxamide; L-valine derivative; ureas	antiviral drug; environmental contaminant; HIV protease inhibitor; xenobiotic
tizoxanide	[no description available]	medium	1	salicylamides
arbutin	[no description available]	medium	1	beta-D-glucoside; monosaccharide derivative	Escherichia coli metabolite; plant metabolite
conessine	[no description available]	medium	1	steroid alkaloid; tertiary amino compound	antibacterial agent; antimalarial; H3-receptor antagonist; plant metabolite
saquinavir	[no description available]	medium	1	L-asparagine derivative; quinolines	antiviral drug; HIV protease inhibitor
abacavir	[no description available]	medium	1	2,6-diaminopurines	antiviral drug; drug allergen; HIV-1 reverse transcriptase inhibitor
linezolid	[no description available]	medium	1	acetamides; morpholines; organofluorine compound; oxazolidinone	antibacterial drug; protein synthesis inhibitor
(-)-usnic acid	[no description available]	medium	1	usnic acid	EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
acetylleucyl-leucyl-norleucinal	[no description available]	medium	1	aldehyde; tripeptide	cysteine protease inhibitor
resveratrol	[no description available]	medium	1	resveratrol	antioxidant; phytoalexin; plant metabolite; quorum sensing inhibitor; radical scavenger
tacrolimus	[no description available]	medium	1	macrolide lactam	bacterial metabolite; immunosuppressive agent
lycopene	[no description available]	medium	1	acyclic carotene	antioxidant; plant metabolite
zithromax	[no description available]	medium	1	macrolide antibiotic	antibacterial drug; environmental contaminant; xenobiotic
roflumilast	[no description available]	medium	1	aromatic ether; benzamides; chloropyridine; cyclopropanes; organofluorine compound	anti-asthmatic drug; phosphodiesterase IV inhibitor
L-cycloserine	[no description available]	medium	1	4-amino-1,2-oxazolidin-3-one	anti-HIV agent; anticonvulsant; EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor
h 89	[no description available]	medium	1	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
bevirimat	[no description available]	medium	1	dicarboxylic acid monoester; monocarboxylic acid; pentacyclic triterpenoid	HIV-1 maturation inhibitor; metabolite
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	[no description available]	medium	1	amino aldehyde; carbamate ester; tripeptide	proteasome inhibitor
tenofovir	[no description available]	medium	1	nucleoside analogue; phosphonic acids	antiviral drug; drug metabolite; HIV-1 reverse transcriptase inhibitor
gw 257406x	[no description available]	medium	1
shikonin	[no description available]	medium	1	hydroxy-1,4-naphthoquinone
4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide	[no description available]	medium	1	tropane alkaloid
cmx 001	[no description available]	medium	1
amd 8664	[no description available]	medium	1
bay 41-4109	[no description available]	medium	1
bay 57-1293	[no description available]	medium	1
isoxanthohumol	[no description available]	medium	1	flavanones
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide	[no description available]	medium	1	aromatic ether
mecarbinate	[no description available]	medium	1
acetyl-aspartyl-glutamyl-valyl-aspartal	[no description available]	medium	1	tetrapeptide	protease inhibitor
octotropine methylbromide	[no description available]	medium	1
mercaptopurine	[no description available]	medium	1	aryl thiol; purines; thiocarbonyl compound	anticoronaviral agent; antimetabolite; antineoplastic agent
jrf 12	[no description available]	medium	1
3,4'-dihydroxyflavone	[no description available]	medium	1
3-(3,4-dimethoxyphenyl)propenoic acid	[no description available]	medium	1	methoxycinnamic acid
isoferulic acid	[no description available]	medium	1	ferulic acids	antioxidant; biomarker; metabolite
cyclouridine	[no description available]	medium	1
zucapsaicin	[no description available]	medium	1	methoxybenzenes; phenols
nbd 556	[no description available]	medium	1
thioguanine anhydrous	[no description available]	medium	1	2-aminopurines	anticoronaviral agent; antimetabolite; antineoplastic agent
4,5,6,7-tetrachloroindan-1,3-dione	[no description available]	medium	1
srpin340	[no description available]	medium	1
pr-619	[no description available]	medium	1
p5091	[no description available]	medium	1
trovirdine	[no description available]	medium	1
fti 277	[no description available]	medium	1
u 0126	[no description available]	medium	1	aryl sulfide; dinitrile; enamine; substituted aniline	antineoplastic agent; antioxidant; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; osteogenesis regulator; vasoconstrictor agent
vicriviroc	[no description available]	medium	1	(trifluoromethyl)benzenes
telaprevir	[no description available]	medium	1	cyclopentapyrrole; cyclopropanes; oligopeptide; pyrazines	antiviral drug; hepatitis C protease inhibitor; peptidomimetic
orlistat	[no description available]	medium	1	beta-lactone; carboxylic ester; formamides; L-leucine derivative	anti-obesity agent; bacterial metabolite; EC 2.3.1.85 (fatty acid synthase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor
dasatinib	[no description available]	medium	1	1,3-thiazoles; aminopyrimidine; monocarboxylic acid amide; N-(2-hydroxyethyl)piperazine; N-arylpiperazine; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
yya-021	[no description available]	medium	1
sb 415286	[no description available]	medium	1	C-nitro compound; maleimides; monochlorobenzenes; phenols; secondary amino compound; substituted aniline	antioxidant; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; neuroprotective agent
sitagliptin	[no description available]	medium	1	triazolopyrazine; trifluorobenzene	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; environmental contaminant; hypoglycemic agent; serine proteinase inhibitor; xenobiotic
tak-220	[no description available]	medium	1
jtk-303	[no description available]	medium	1	aromatic ether; monochlorobenzenes; organofluorine compound; quinolinemonocarboxylic acid; quinolone	HIV-1 integrase inhibitor
nbd 557	[no description available]	medium	1
5'-o-caffeoylquinic acid	[no description available]	medium	1	cinnamate ester; cyclitol carboxylic acid	plant metabolite
cyclosporine	[no description available]	medium	1
harmine	[no description available]	medium	1	harmala alkaloid	anti-HIV agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; metabolite
eprosartan	[no description available]	medium	1	dicarboxylic acid; imidazoles; thiophenes	angiotensin receptor antagonist; antihypertensive agent; environmental contaminant; xenobiotic
entacapone	[no description available]	medium	1	2-nitrophenols; catechols; monocarboxylic acid amide; nitrile	antidyskinesia agent; antiparkinson drug; central nervous system drug; EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
amentoflavone	[no description available]	medium	1	biflavonoid; hydroxyflavone; ring assembly	angiogenesis inhibitor; antiviral agent; cathepsin B inhibitor; P450 inhibitor; plant metabolite
baicalein	[no description available]	medium	1	trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; ferroptosis inhibitor; geroprotector; hormone antagonist; plant metabolite; prostaglandin antagonist; radical scavenger
genkwanin	[no description available]	medium	1	dihydroxyflavone; monomethoxyflavone	metabolite
hyperoside	[no description available]	medium	1	beta-D-galactoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	hepatoprotective agent; plant metabolite
3-methylquercetin	[no description available]	medium	1	7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone	anticoagulant; EC 1.14.18.1 (tyrosinase) inhibitor; metabolite
kaempferide	[no description available]	medium	1	7-hydroxyflavonol; monomethoxyflavone; trihydroxyflavone	antihypertensive agent; metabolite
orientin	[no description available]	medium	1	3'-hydroxyflavonoid; C-glycosyl compound; tetrahydroxyflavone	antioxidant; metabolite
scutellarein	[no description available]	medium	1	tetrahydroxyflavone	metabolite
trans-2,3',4,5'-tetrahydroxystilbene	[no description available]	medium	1	stilbenoid
polydatin	[no description available]	medium	1	beta-D-glucoside; monosaccharide derivative; polyphenol; stilbenoid	anti-arrhythmia drug; antioxidant; geroprotector; hepatoprotective agent; metabolite; nephroprotective agent; potassium channel modulator
chicoric acid	[no description available]	medium	1	organooxygen compound	geroprotector; HIV-1 integrase inhibitor
acteoside	[no description available]	medium	1	catechols; cinnamate ester; disaccharide derivative; glycoside; polyphenol	anti-inflammatory agent; antibacterial agent; antileishmanial agent; neuroprotective agent; plant metabolite
dorzolamide	[no description available]	medium	1	sulfonamide; thiophenes	antiglaucoma drug; antihypertensive agent; EC 4.2.1.1 (carbonic anhydrase) inhibitor
topiramate	[no description available]	medium	1	cyclic ketal; ketohexose derivative; sulfamate ester	anticonvulsant; sodium channel blocker
benzyloxycarbonyl-phe-ala-fluormethylketone	[no description available]	medium	1
n-(n-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester	[no description available]	medium	1	carboxylic ester; difluorobenzene; dipeptide; tert-butyl ester	EC 3.4.23.46 (memapsin 2) inhibitor
casticin	[no description available]	medium	1	dihydroxyflavone; tetramethoxyflavone	apoptosis inducer; plant metabolite
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one	[no description available]	medium	1	dihydroxyflavone; monomethoxyflavone	antineoplastic agent; EC 1.14.13.39 (nitric oxide synthase) inhibitor
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside	[no description available]	medium	1	beta-D-glucoside; resorcinols; stilbenoid	anti-inflammatory agent; antioxidant; apoptosis inhibitor; cardioprotective agent; cyclooxygenase 2 inhibitor; platelet aggregation inhibitor
tyrphostin ag 555	[no description available]	medium	1
pd 151746	[no description available]	medium	1
lisinopril	[no description available]	medium	1	dipeptide	EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
verteporfin	[no description available]	medium	1
batimastat	[no description available]	medium	1	hydroxamic acid; L-phenylalanine derivative; organic sulfide; secondary carboxamide; thiophenes; triamide	angiogenesis inhibitor; antineoplastic agent; matrix metalloproteinase inhibitor
indinavir sulfate	[no description available]	medium	1	dicarboxylic acid diamide; N-(2-hydroxyethyl)piperazine; piperazinecarboxamide	HIV protease inhibitor
solanesol	[no description available]	medium	1	nonaprenol; primary alcohol	plant metabolite
pepstatin	[no description available]	medium	1	pentapeptide; secondary carboxamide	bacterial metabolite; EC 3.4.23.* (aspartic endopeptidase) inhibitor
l 685458	[no description available]	medium	1	carbamate ester; monocarboxylic acid amide; peptide; secondary alcohol	EC 3.4.23.46 (memapsin 2) inhibitor; peptidomimetic
bms 806	[no description available]	medium	1
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	[no description available]	medium	1
tulobuterol hydrochloride	[no description available]	medium	1	organic molecular entity
salubrinal	[no description available]	medium	1	aminal; organochlorine compound; quinolines; secondary carboxamide; thioureas
germacrone	[no description available]	medium	1	germacrane sesquiterpenoid; olefinic compound	androgen antagonist; anti-inflammatory agent; antifeedant; antifungal agent; antimicrobial agent; antineoplastic agent; antioxidant; antitussive; antiviral agent; apoptosis inducer; autophagy inducer; hepatoprotective agent; insecticide; neuroprotective agent; plant metabolite; volatile oil component
(2e,4e,6e,10e)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid	[no description available]	medium	1
lithospermic acid	[no description available]	medium	1
laq824	[no description available]	medium	1
ekb 569	[no description available]	medium	1	aminoquinoline; monocarboxylic acid amide; monochlorobenzenes; nitrile	protein kinase inhibitor
rilpivirine	[no description available]	medium	1	aminopyrimidine; nitrile	EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor; HIV-1 reverse transcriptase inhibitor
(1Ar,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one	[no description available]	medium	1	germacranolide
4,5-di-O-caffeoylquinic acid	[no description available]	medium	1	quinic acid
indigo carmine	[no description available]	medium	1
artesunate	[no description available]	medium	1	artemisinin derivative; cyclic acetal; dicarboxylic acid monoester; hemisuccinate; semisynthetic derivative; sesquiterpenoid	antimalarial; antineoplastic agent; ferroptosis inducer
(3S,6S,9S,12R)-3-[(2S)-Butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone	[no description available]	medium	1	oligopeptide
vildagliptin	[no description available]	medium	1	amino acid amide
belinostat	[no description available]	medium	1	hydroxamic acid; olefinic compound; sulfonamide	antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor
hdac-42	[no description available]	medium	1	amidobenzoic acid
chlorhexidine	[no description available]	medium	1	biguanides; monochlorobenzenes	antibacterial agent; antiinfective agent
gs-7340	[no description available]	medium	1	6-aminopurines; ether; isopropyl ester; L-alanine derivative; phosphoramidate ester	antiviral drug; HIV-1 reverse transcriptase inhibitor; prodrug
iniparib	[no description available]	medium	1	carbonyl compound; organohalogen compound
n-(2-amino-5-fluorobenzyl)-4-(n-(pyridine-3-acrylyl)aminomethyl)benzamide	[no description available]	medium	1
pri-2205	[no description available]	medium	1
mk 0752	[no description available]	medium	1
givinostat	[no description available]	medium	1	carbamate ester
pd 144418	[no description available]	medium	1
bicyclol	[no description available]	medium	1
midostaurin	[no description available]	medium	1	benzamides; gamma-lactam; indolocarbazole; organic heterooctacyclic compound	antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
ly 450139	[no description available]	medium	1	peptide
mocetinostat	[no description available]	medium	1	aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline	antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent
rivaroxaban	[no description available]	medium	1	aromatic amide; lactam; monocarboxylic acid amide; morpholines; organochlorine compound; oxazolidinone; thiophenes	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
sb 3ct compound	[no description available]	medium	1	aromatic ether
ginsenoside rb1	[no description available]	medium	1	ginsenoside; glycoside; tetracyclic triterpenoid	anti-inflammatory drug; anti-obesity agent; apoptosis inhibitor; neuroprotective agent; plant metabolite; radical scavenger
rucaparib	[no description available]	medium	1	azepinoindole; caprolactams; organofluorine compound; secondary amino compound	antineoplastic agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-n-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6s)-	[no description available]	medium	1	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
cetilistat	[no description available]	medium	1	benzoxazine
ym 201636	[no description available]	medium	1	aromatic amide
linagliptin	[no description available]	medium	1	aminopiperidine; quinazolines	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; hypoglycemic agent
azd 6244	[no description available]	medium	1	benzimidazoles; bromobenzenes; hydroxamic acid ester; monochlorobenzenes; organofluorine compound; secondary amino compound	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
odanacatib	[no description available]	medium	1
apilimod	[no description available]	medium	1
apixaban	[no description available]	medium	1	aromatic ether; lactam; piperidones; pyrazolopyridine	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
betrixaban	[no description available]	medium	1	benzamides; guanidines; monochloropyridine; monomethoxybenzene; secondary carboxamide	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor
edoxaban	[no description available]	medium	1	chloropyridine; monocarboxylic acid amide; tertiary amino compound; thiazolopyridine	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor; platelet aggregation inhibitor
saracatinib	[no description available]	medium	1	aromatic ether; benzodioxoles; diether; N-methylpiperazine; organochlorine compound; oxanes; quinazolines; secondary amino compound	anticoronaviral agent; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; radiosensitizing agent
n-(3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl)-3-(2-((((1,1-dimethylethyl)amino)carbonyl)amino)-3,3-dimethyl-1-oxobutyl)-6,6-dimethyl-3-azabicyclo(3.1.0)hexan-2-carboxamide	[no description available]	medium	1	tripeptide; ureas	antiviral drug; hepatitis C protease inhibitor; peptidomimetic
ly 411575	[no description available]	medium	1	dibenzoazepine; difluorobenzene; lactam; secondary alcohol	EC 3.4.23.46 (memapsin 2) inhibitor
PB28	[no description available]	medium	1	aromatic ether; piperazines; tetralins	anticoronaviral agent; antineoplastic agent; apoptosis inducer; sigma-2 receptor agonist
degrasyn	[no description available]	medium	1
epoxomicin	[no description available]	medium	1	morpholines; tripeptide	proteasome inhibitor
bms 477118	[no description available]	medium	1	adamantanes; azabicycloalkane; monocarboxylic acid amide; nitrile; tertiary alcohol	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; hypoglycemic agent
pha 680632	[no description available]	medium	1
tmc 353121	[no description available]	medium	1
amd 070	[no description available]	medium	1	aminoquinoline
danoprevir	[no description available]	medium	1
bms-626529	[no description available]	medium	1
bms-663068	[no description available]	medium	1
amenamevir	[no description available]	medium	1
vx 765	[no description available]	medium	1	dipeptide
Dihydrotanshinone I	[no description available]	medium	1	abietane diterpenoid	anticoronaviral agent
alogliptin	[no description available]	medium	1	nitrile; piperidines; primary amino compound; pyrimidines	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; hypoglycemic agent
fr 180204	[no description available]	medium	1	pyrazoles; ring assembly
quisinostat	[no description available]	medium	1	indoles
carfilzomib	[no description available]	medium	1	epoxide; morpholines; tetrapeptide	antineoplastic agent; proteasome inhibitor
hcv 796	[no description available]	medium	1
resminostat	[no description available]	medium	1
zk 756326	[no description available]	medium	1	aromatic ether
balapiravir	[no description available]	medium	1
trametinib	[no description available]	medium	1	acetamides; aromatic amine; cyclopropanes; organofluorine compound; organoiodine compound; pyridopyrimidine; ring assembly	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
deoxyarbutin	[no description available]	medium	1
abexinostat	[no description available]	medium	1	benzofurans
silvestrol	[no description available]	medium	1	dioxanes; ether; methyl ester; organic heterotricyclic compound	antineoplastic agent; metabolite
narlaprevir	[no description available]	medium	1	azabicyclohexane; cyclopropanes; pyrrolidinecarboxamide; secondary carboxamide; sulfone; tertiary carboxamide; ureas	anticoronaviral agent; antiviral drug; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; hepatitis C protease inhibitor
teneligliptin	[no description available]	medium	1	amino acid amide
dextrothyroxine	[no description available]	medium	1
veliparib	[no description available]	medium	1	benzimidazoles	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
pf 03491390	[no description available]	medium	1
alloin	[no description available]	medium	1	anthracenes; C-glycosyl compound; cyclic ketone; phenols	laxative; metabolite
mdv 3100	[no description available]	medium	1	(trifluoromethyl)benzenes; benzamides; imidazolidinone; monofluorobenzenes; nitrile; thiocarbonyl compound	androgen antagonist; antineoplastic agent
bms-650032	[no description available]	medium	1	oligopeptide
rg 7128	[no description available]	medium	1
oritavancin	[no description available]	medium	1	disaccharide derivative; glycopeptide; semisynthetic derivative	antibacterial drug; antimicrobial agent
pevonedistat	[no description available]	medium	1	cyclopentanols; indanes; pyrrolopyrimidine; secondary amino compound; sulfamidate	antineoplastic agent; apoptosis inducer
uk 453,061	[no description available]	medium	1	aromatic ether
N-(2-aminophenyl)-2-pyrazinecarboxamide	[no description available]	medium	1	aromatic amide
tegobuvir	[no description available]	medium	1
pf-429242	[no description available]	medium	1
olaparib	[no description available]	medium	1	cyclopropanes; monofluorobenzenes; N-acylpiperazine; phthalazines	antineoplastic agent; apoptosis inducer; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
cx 4945	[no description available]	medium	1
pci 34051	[no description available]	medium	1	indolecarboxamide
lomibuvir	[no description available]	medium	1	thiophenecarboxylic acid
delanzomib	[no description available]	medium	1	C-terminal boronic acid peptide; phenylpyridine; secondary alcohol; threonine derivative	antineoplastic agent; apoptosis inducer; proteasome inhibitor
pitavastatin(1-)	[no description available]	medium	1	hydroxy monocarboxylic acid anion
GRL-0617	[no description available]	medium	1	benzamides; naphthalenes; secondary carboxamide; substituted aniline	anticoronaviral agent; protease inhibitor
N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]-oxomethyl]-5-isoxazolyl]phenyl]carbamic acid tert-butyl ester	[no description available]	medium	1	carbamate ester
niraparib	[no description available]	medium	1	2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide	antineoplastic agent; apoptosis inducer; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; radiosensitizing agent
jzl 184	[no description available]	medium	1	benzodioxoles
gsk 650394	[no description available]	medium	1	phenylpyridine
oprozomib	[no description available]	medium	1
az 960	[no description available]	medium	1
golgicide a	[no description available]	medium	1	diastereoisomeric mixture	cis-Golgi ArfGEF GBF inhibitor
cobicistat	[no description available]	medium	1	1,3-thiazoles; carbamate ester; monocarboxylic acid amide; morpholines; ureas	P450 inhibitor
bms-790052	[no description available]	medium	1	biphenyls; carbamate ester; carboxamide; imidazoles; valine derivative	antiviral drug; nonstructural protein 5A inhibitor
ixazomib	[no description available]	medium	1	benzamides; boronic acids; dichlorobenzene; glycine derivative	antineoplastic agent; apoptosis inducer; drug metabolite; orphan drug; proteasome inhibitor
ucph 101	[no description available]	medium	1
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine	[no description available]	medium	1	aryl sulfide; thienopyrimidine
baricitinib	[no description available]	medium	1	azetidines; nitrile; pyrazoles; pyrrolopyrimidine; sulfonamide	anti-inflammatory agent; antirheumatic drug; antiviral agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; immunosuppressive agent
KOM70144	[no description available]	medium	1	acetamides; benzamides; naphthalenes; secondary carboxamide	anticoronaviral agent; protease inhibitor
e-52862	[no description available]	medium	1
ly2811376	[no description available]	medium	1
anagliptin	[no description available]	medium	1	amino acid amide
gardiquimod	[no description available]	medium	1
grazoprevir	[no description available]	medium	1	aromatic ether; azamacrocycle; carbamate ester; cyclopropanes; lactam; N-sulfonylcarboxamide; quinoxaline derivative	antiviral drug; hepatitis C protease inhibitor; hepatoprotective agent
abt-450	[no description available]	medium	1
letermovir	[no description available]	medium	1
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine	[no description available]	medium	1	benzoxazole
blz 945	[no description available]	medium	1
azd3839	[no description available]	medium	1
pf 3084014	[no description available]	medium	1
unc 0638	[no description available]	medium	1	quinazolines
gs-9620	[no description available]	medium	1
n-((5-(methanesulfonyl)pyridin-2-yl)methyl)-6-methyl-5-(1-methyl-1h-pyrazol-5-yl)-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide	[no description available]	medium	1
bms 708163	[no description available]	medium	1	oxadiazole; ring assembly
jq1 compound	[no description available]	medium	1	carboxylic ester; organochlorine compound; tert-butyl ester; thienotriazolodiazepine	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bromodomain-containing protein 4 inhibitor; cardioprotective agent; ferroptosis inducer
1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone	[no description available]	medium	1
gsk525762a	[no description available]	medium	1	benzodiazepine
ML240	[no description available]	medium	1	aromatic amine; aromatic ether; benzimidazoles; primary amino compound; quinazolines; secondary amino compound	antineoplastic agent
birinapant	[no description available]	medium	1	dipeptide
ly2886721	[no description available]	medium	1
nms-p118	[no description available]	medium	1
tubastatin a	[no description available]	medium	1	hydroxamic acid; pyridoindole; tertiary amino compound	EC 3.5.1.98 (histone deacetylase) inhibitor
pracinostat	[no description available]	medium	1	benzimidazole; hydroxamic acid; olefinic compound; tertiary amino compound	antimalarial; antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
spautin-1	[no description available]	medium	1
ldn 57444	[no description available]	medium	1
gsk1210151a	[no description available]	medium	1	imidazoquinoline
i-bet726	[no description available]	medium	1
acy-1215	[no description available]	medium	1	pyrimidinecarboxylic acid
cudc-907	[no description available]	medium	1
mobic	[no description available]	medium	1	1,3-thiazoles; benzothiazine; monocarboxylic acid amide	analgesic; antirheumatic drug; cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug
tipranavir	[no description available]	medium	1	sulfonamide	antiviral drug; HIV protease inhibitor
tasquinimod	[no description available]	medium	1
gsk1265744	[no description available]	medium	1	difluorobenzene; monocarboxylic acid amide; organic heterotricyclic compound; secondary carboxamide	HIV-1 integrase inhibitor
abt-267	[no description available]	medium	1	aromatic amide; carbamate ester; dipeptide; pyrrolidines	antiviral drug; hepatitis C virus nonstructural protein 5A inhibitor
abt-333	[no description available]	medium	1	aromatic ether; naphthalenes; pyrimidone; sulfonamide	antiviral drug; nonnucleoside hepatitis C virus polymerase inhibitor
rgfp966	[no description available]	medium	1
rg2833	[no description available]	medium	1
pi-1840	[no description available]	medium	1
acy-738	[no description available]	medium	1
pelabresib	[no description available]	medium	1	monochlorobenzenes; organic heterotricyclic compound; primary carboxamide	antineoplastic agent; bromodomain-containing protein 4 inhibitor
gs-5806	[no description available]	medium	1
doravirine	[no description available]	medium	1
gn6958	[no description available]	medium	1
vx-787	[no description available]	medium	1
ledipasvir	[no description available]	medium	1	azaspiro compound; benzimidazole; bridged compound; carbamate ester; carboxamide; fluorenes; imidazoles; L-valine derivative; N-acylpyrrolidine; organofluorine compound	antiviral drug; hepatitis C protease inhibitor
gs-5816	[no description available]	medium	1	carbamate ester; ether; imidazoles; L-valine derivative; N-acylpyrrolidine; organic heteropentacyclic compound; ring assembly	antiviral drug; hepatitis C virus nonstructural protein 5A inhibitor
g007-lk	[no description available]	medium	1
4-((1-butyl-3-phenylureido)methyl)-n-hydroxybenzamide	[no description available]	medium	1
selinexor	[no description available]	medium	1
verdinexor	[no description available]	medium	1
cb-839	[no description available]	medium	1
mk-8742	[no description available]	medium	1	carbamate ester; imidazoles; L-valine derivative; N-acylpyrrolidine; organic heterotetracyclic compound; ring assembly	antiviral drug; hepatitis C virus nonstructural protein 5A inhibitor; hepatoprotective agent
atglistatin	[no description available]	medium	1
xen445	[no description available]	medium	1
santacruzamate a	[no description available]	medium	1	organonitrogen compound; organooxygen compound
ldc4297	[no description available]	medium	1	aromatic ether; piperidines; pyrazoles; pyrazolotriazine; secondary amino compound	antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
enasidenib	[no description available]	medium	1	1,3,5-triazines; aminopyridine; aromatic amine; organofluorine compound; secondary amino compound; tertiary alcohol	antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
entecavir	[no description available]	medium	1	2-aminopurines; oxopurine; primary alcohol; secondary alcohol	antiviral drug; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
acyclovir	[no description available]	medium	1	2-aminopurines; oxopurine	antimetabolite; antiviral drug
nu 1025	[no description available]	medium	1	phenols; quinazolines	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
didanosine	[no description available]	medium	1	purine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor; geroprotector; HIV-1 reverse transcriptase inhibitor
ganciclovir	[no description available]	medium	1	2-aminopurines; oxopurine	antiinfective agent; antiviral drug
valacyclovir	[no description available]	medium	1	L-valyl ester	antiviral drug
4-hydroxyquinazoline	[no description available]	medium	1	quinazolines
tegaserod	[no description available]	medium	1	carboxamidine; guanidines; hydrazines; indoles	gastrointestinal drug; serotonergic agonist
norclozapine	[no description available]	medium	1	dibenzodiazepine; organochlorine compound; piperazines	delta-opioid receptor agonist; metabolite; serotonergic antagonist
pemetrexed	[no description available]	medium	1	N-acyl-L-glutamic acid; pyrrolopyrimidine	antimetabolite; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; EC 2.1.1.45 (thymidylate synthase) inhibitor; EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
aprepitant	[no description available]	medium	1	(trifluoromethyl)benzenes; cyclic acetal; morpholines; triazoles	antidepressant; antiemetic; neurokinin-1 receptor antagonist; peripheral nervous system drug; substance P receptor antagonist
azilsartan	[no description available]	medium	1	1,2,4-oxadiazole; aromatic ether; benzimidazolecarboxylic acid	angiotensin receptor antagonist; antihypertensive agent
hesperadin	[no description available]	medium	1
6-bromoindirubin-3'-acetoxime	[no description available]	medium	1
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide	[no description available]	medium	1	catechols; hydrazide; hydrazone; naphthols	EC 3.6.5.5 (dynamin GTPase) inhibitor
XL413	[no description available]	medium	1	benzofuropyrimidine; organochlorine compound; pyrrolidines	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
me0328	[no description available]	medium	1
nvp-tnks656	[no description available]	medium	1
isoproterenol	[no description available]	medium	1	catechols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; sympathomimetic agent
nifedipine	[no description available]	medium	8
tamoxifen	[no description available]	medium	1	stilbenoid; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; bone density conservation agent; EC 1.2.3.1 (aldehyde oxidase) inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; estrogen antagonist; estrogen receptor antagonist; estrogen receptor modulator
carbamates	[no description available]	medium	1	amino-acid anion
dimethyl sulfoxide	[no description available]	medium	1	sulfoxide; volatile organic compound	alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger
bufalin	[no description available]	medium	2	14beta-hydroxy steroid; 3beta-hydroxy steroid	animal metabolite; anti-inflammatory agent; antineoplastic agent; cardiotonic drug
cardiovascular agents	[no description available]	medium	1
deoxycytidine	[no description available]	medium	1	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
oxymatrine	[no description available]	medium	1	alkaloid; tertiary amine oxide
adenosine monophosphate	[no description available]	medium	1	adenosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	adenosine A1 receptor agonist; cofactor; EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.11 (fructose-bisphosphatase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
alanine	[no description available]	medium	1	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
alpha-synuclein	[no description available]	medium	1
gold	[no description available]	medium	1	copper group element atom; elemental gold
folic acid	[no description available]	medium	1	folic acids; N-acyl-amino acid	human metabolite; mouse metabolite; nutrient
fluorescein	[no description available]	medium	1	2-benzofurans; gamma-lactone; organic heteropentacyclic compound; oxaspiro compound; polyphenol; xanthene dye	fluorescent dye; radioopaque medium
cyclin d1	[no description available]	medium	3
glycosides	[no description available]	medium	1
ungeremine	[no description available]	medium	2
chlorpropham	[no description available]	medium	1	benzenes; carbamate ester; monochlorobenzenes	herbicide; plant growth retardant
benzylaminopurine	[no description available]	medium	1	6-aminopurines	cytokinin; plant metabolite
kinetin	[no description available]	medium	1	6-aminopurines; furans	cytokinin; geroprotector
2,4-dichlorophenoxyacetic acid	[no description available]	medium	1	chlorophenoxyacetic acid; dichlorobenzene	agrochemical; defoliant; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; environmental contaminant; phenoxy herbicide; synthetic auxin
3,5-dibromo-2-pyrone	[no description available]	medium	1
chloroform	[no description available]	medium	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant
methanol	[no description available]	medium	2	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
epidermal growth factor	[no description available]	medium	1
titanium	[no description available]	medium	1	titanium group element atom
triazoles	[no description available]	medium	1	1,2,3-triazole
1,1,1-triacetoxy-1,1-dihydro-1,2-benziodoxol-3(1h)-one	[no description available]	medium	1
cytochrome c-t	[no description available]	medium	2
bromobenzene	[no description available]	medium	1	bromoarene; bromobenzenes; volatile organic compound	hepatotoxic agent; mouse metabolite; non-polar solvent
hemanthidine	[no description available]	medium	2
bezafibrate	[no description available]	medium	1	aromatic ether; monocarboxylic acid amide; monocarboxylic acid; monochlorobenzenes	antilipemic drug; environmental contaminant; geroprotector; xenobiotic
adenosine	[no description available]	medium	1	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
4-hydroxybenzaldehyde	[no description available]	medium	1	hydroxybenzaldehyde	EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor; mouse metabolite; plant metabolite
sucrose	[no description available]	medium	1	glycosyl glycoside	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; sweetening agent
carbon tetrachloride	[no description available]	medium	1	chlorocarbon; chloromethanes	hepatotoxic agent; refrigerant
deuterium	[no description available]	medium	1	dihydrogen
buthionine sulfoximine	[no description available]	medium	1	diastereoisomeric mixture; homocysteines; non-proteinogenic alpha-amino acid; sulfoximide	EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor; ferroptosis inducer
ascorbic acid	[no description available]	medium	14	ascorbic acid; vitamin C	coenzyme; cofactor; flour treatment agent; food antioxidant; food colour retention agent; geroprotector; plant metabolite; skin lightening agent
dehydroascorbic acid	[no description available]	medium	3	dehydroascorbic acid; vitamin C	coenzyme; mouse metabolite
dinoprostone	[no description available]	medium	1	prostaglandins E	human metabolite; mouse metabolite; oxytocic
gibberellins	[no description available]	medium	2
abscisic acid	[no description available]	medium	2	2-trans-abscisic acid
malondialdehyde	[no description available]	medium	1	dialdehyde	biomarker
pyrroles	[no description available]	medium	1	pyrrole; secondary amine
thiourea	[no description available]	medium	1	one-carbon compound; thioureas; ureas	antioxidant; chromophore
mannose	[no description available]	medium	1	D-aldohexose; D-mannose; mannopyranose	metabolite
oleic acid	[no description available]	medium	1	octadec-9-enoic acid	antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent
oxadiazoles	[no description available]	medium	1
galactonic acid	[no description available]	medium	1	galactonic acid
adenine	[no description available]	medium	1	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
guanine	[no description available]	medium	1	2-aminopurines; oxopurine; purine nucleobase	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
cherylline	[no description available]	medium	1	isoquinolines
galactonolactone	[no description available]	medium	3
ferulic acid	[no description available]	medium	1	ferulic acids	anti-inflammatory agent; antioxidant; apoptosis inhibitor; cardioprotective agent; MALDI matrix material; plant metabolite
guaiacol	[no description available]	medium	1	guaiacols	disinfectant; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; expectorant; plant metabolite
linoleic acid	[no description available]	medium	1	octadecadienoic acid; omega-6 fatty acid	algal metabolite; Daphnia galeata metabolite; plant metabolite
quercetin-3'-o-beta-d-glucopyranoside	[no description available]	medium	1
glucose, (beta-d)-isomer	[no description available]	medium	1	D-glucopyranose	epitope; mouse metabolite
rutin	[no description available]	medium	1	disaccharide derivative; quercetin O-glucoside; rutinoside; tetrahydroxyflavone	antioxidant; metabolite
concanavalin a	[no description available]	medium	1
dapi	[no description available]	medium	1	indoles	fluorochrome
methionine	[no description available]	medium	1	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
cysteine	[no description available]	medium	1	cysteinium	fundamental metabolite
ribose	[no description available]	medium	1	D-ribose; ribopyranose
staurosporine	[no description available]	medium	1	ammonium ion derivative
verapamil	[no description available]	medium	1	aromatic ether; nitrile; polyether; tertiary amino compound
leucine	[no description available]	medium	1	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
phentolamine	[no description available]	medium	1	imidazoles; phenols; substituted aniline; tertiary amino compound	alpha-adrenergic antagonist; vasodilator agent
phenylephrine	[no description available]	medium	1	phenols; phenylethanolamines; secondary amino compound	alpha-adrenergic agonist; cardiotonic drug; mydriatic agent; nasal decongestant; protective agent; sympathomimetic agent; vasoconstrictor agent
acetopyrrothine	[no description available]	low	0	acetamides; dithiolopyrrolone antibiotic	angiogenesis inhibitor; antibacterial agent; antifungal agent; antineoplastic agent; bacterial metabolite; chelator; EC 2.7.7.6 (RNA polymerase) inhibitor; marine metabolite; protein synthesis inhibitor; toxin
streptomycin	[no description available]	low	0	antibiotic antifungal drug; antibiotic fungicide; streptomycins	antibacterial drug; antifungal agrochemical; antimicrobial agent; antimicrobial drug; bacterial metabolite; protein synthesis inhibitor
arbekacin	[no description available]	low	0	aminoglycoside; kanamycins	antibacterial agent; antibacterial drug; antimicrobial agent; protein synthesis inhibitor
nucleocidin	[no description available]	low	0	6-aminopurines; adenosines; diol; organofluorine compound; sulfamate ester	antibacterial agent; bacterial metabolite; nucleoside antibiotic; protein synthesis inhibitor; trypanocidal drug
clarithromycin	[no description available]	low	0	macrolide antibiotic	antibacterial drug; environmental contaminant; protein synthesis inhibitor; xenobiotic
cryptopleurine	[no description available]	low	0	alkaloid antibiotic; alkaloid; aromatic ether; organic heteropentacyclic compound	antineoplastic agent; antiviral agent; protein synthesis inhibitor
s-2-aminoethyl cysteine	[no description available]	low	0	L-cysteine thioether; non-proteinogenic L-alpha-amino acid	EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor; metabolite; protein synthesis inhibitor
a 195773	[no description available]	low	0	macrolide antibiotic; monosaccharide derivative; quinolines	antibacterial drug; protein synthesis inhibitor
homoharringtonine	[no description available]	low	0	alkaloid ester; enol ether; organic heteropentacyclic compound; tertiary alcohol	anticoronaviral agent; antineoplastic agent; apoptosis inducer; protein synthesis inhibitor
mupirocin	[no description available]	low	0	alpha,beta-unsaturated carboxylic ester; epoxide; monocarboxylic acid; oxanes; secondary alcohol; triol	antibacterial drug; bacterial metabolite; protein synthesis inhibitor
dibekacin	[no description available]	low	0	kanamycins	antibacterial agent; protein synthesis inhibitor
fusidic acid	[no description available]	low	0	11alpha-hydroxy steroid; 3alpha-hydroxy steroid; alpha,beta-unsaturated monocarboxylic acid; steroid acid; steroid antibiotic; sterol ester	EC 2.7.1.33 (pantothenate kinase) inhibitor; Escherichia coli metabolite; protein synthesis inhibitor
emetine dihydrochloride	[no description available]	low	0	hydrochloride	anticoronaviral agent; antimalarial; antineoplastic agent; antiprotozoal drug; antiviral agent; autophagy inhibitor; emetic; protein synthesis inhibitor
tedizolid	[no description available]	low	0	carbamate ester; organofluorine compound; oxazolidinone; primary alcohol; pyridines; tetrazoles	antimicrobial agent; drug metabolite; protein synthesis inhibitor
tedizolid phosphate	[no description available]	low	0	carbamate ester; organofluorine compound; oxazolidinone; phosphate monoester; pyridines; tetrazoles	antimicrobial agent; prodrug; protein synthesis inhibitor
tavaborole	[no description available]	low	0	benzoxaborole; organofluorine compound	antifungal agent; EC 6.1.1.4 (leucine--tRNA ligase) inhibitor; protein synthesis inhibitor
gamithromycin	[no description available]	low	0	macrolide antibiotic; monosaccharide derivative	antibacterial drug; protein synthesis inhibitor
rifampin	[no description available]	low	0	cyclic ketal; hydrazone; N-iminopiperazine; N-methylpiperazine; rifamycins; semisynthetic derivative; zwitterion	angiogenesis inhibitor; antiamoebic agent; antineoplastic agent; antitubercular agent; DNA synthesis inhibitor; EC 2.7.7.6 (RNA polymerase) inhibitor; Escherichia coli metabolite; geroprotector; leprostatic drug; neuroprotective agent; pregnane X receptor agonist; protein synthesis inhibitor
althiomycin	[no description available]	low	0	1,3-thiazoles; aldoxime; ether; gamma-lactam; pentapeptide; peptide antibiotic; primary alcohol; pyrroline; secondary carboxamide; tertiary carboxamide	antibacterial agent; bacterial metabolite; protein synthesis inhibitor
dapsone	[no description available]	low	0	substituted aniline; sulfone	anti-inflammatory drug; antiinfective agent; antimalarial; leprostatic drug
primaquine	[no description available]	low	0	aminoquinoline; aromatic ether; N-substituted diamine	antimalarial
triclosan	[no description available]	low	0	aromatic ether; dichlorobenzene; monochlorobenzenes; phenols	antibacterial agent; antimalarial; drug allergen; EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; fungicide; persistent organic pollutant; xenobiotic
methylene blue	[no description available]	low	0	organic chloride salt	acid-base indicator; antidepressant; antimalarial; antimicrobial agent; antioxidant; cardioprotective agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 4.6.1.2 (guanylate cyclase) inhibitor; fluorochrome; histological dye; neuroprotective agent; physical tracer
acedapsone	[no description available]	low	0	acetamides; anilide; secondary carboxamide; sulfone	antimalarial; antimicrobial drug
sulfadoxine	[no description available]	low	0	pyrimidines; sulfonamide	antibacterial drug; antimalarial
dehydroemetine	[no description available]	low	0	aromatic ether; isoquinolines; pyridoisoquinoline	antileishmanial agent; antimalarial; antiprotozoal drug
artemether	[no description available]	low	0	artemisinin derivative; cyclic acetal; organic peroxide; semisynthetic derivative; sesquiterpenoid	antimalarial
vexibinol	[no description available]	low	0	(2S)-flavan-4-one; 4'-hydroxyflavanones; tetrahydroxyflavanone	antimalarial; antimicrobial agent; antioxidant; plant metabolite
piperaquine	[no description available]	low	0	aminoquinoline; N-arylpiperazine; organochlorine compound	antimalarial
docetaxel anhydrous	[no description available]	low	0	secondary alpha-hydroxy ketone; tetracyclic diterpenoid	antimalarial; antineoplastic agent; photosensitizing agent
minquartynoic acid	[no description available]	low	0	acetylenic fatty acid; hydroxy polyunsaturated fatty acid; long-chain fatty acid; straight-chain fatty acid; tetrayne	antimalarial; antineoplastic agent; antiviral agent
glaucarubinone	[no description available]	low	0	carboxylic ester; organic heteropentacyclic compound; quassinoid; secondary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone; tetrol	antimalarial; antineoplastic agent; geroprotector; plant metabolite
lactucin	[no description available]	low	0	azulenofuran; cyclic terpene ketone; enone; primary alcohol; secondary alcohol; sesquiterpene lactone	antimalarial; plant metabolite; sedative
dioncophylline a	[no description available]	low	0	biaryl; isoquinoline alkaloid; isoquinolines; methoxynaphthalene; methylnaphthalenes; naphthalenes	antifungal agent; antimalarial; metabolite; molluscicide
dioncophylline c	[no description available]	low	0	aromatic ether; biaryl; isoquinoline alkaloid; isoquinolines; methoxynaphthalene; methylnaphthalenes; naphthols	antimalarial; antiplasmodial drug; metabolite
7-deacetylgedunin	[no description available]	low	0	cyclic terpene ketone; delta-lactone; enone; epoxide; furans; limonoid; pentacyclic triterpenoid	anti-inflammatory agent; antimalarial; metabolite; plant metabolite
adefovir	[no description available]	low	0	aromatic ether; aromatic ketone; biaryl; cyclic ketone; naphtho-gamma-pyrone; organooxygen heterocyclic antibiotic; polyphenol	antimalarial; Aspergillus metabolite; marine metabolite
norlichexanthone	[no description available]	low	0	polyphenol; xanthones	antimalarial; fungal metabolite
nostocarboline	[no description available]	low	0	alkaloid; beta-carbolines; organic cation; organochlorine compound	antimalarial; EC 3.1.1.8 (cholinesterase) inhibitor; metabolite
proguanil	[no description available]	low	0	biguanides; monochlorobenzenes	antimalarial; antiprotozoal drug; EC 1.5.1.3 (dihydrofolate reductase) inhibitor
manzamine a	[no description available]	low	0	alkaloid; beta-carbolines; isoquinolines	animal metabolite; anti-HSV-1 agent; antimalarial; antineoplastic agent; EC 2.7.11.26 (tau-protein kinase) inhibitor; marine metabolite
dihydroartemisinin	[no description available]	low	0	sesquiterpenoid	antimalarial
triacsin c	[no description available]	low	0	hydrazone; nitroso compound; olefinic compound	antimalarial; apoptosis inhibitor; bacterial metabolite; EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; vasodilator agent
bielschowskysin	[no description available]	low	0	acetate ester; cyclic acetal; diterpenoid; gamma-lactone; organic heterohexacyclic compound	antimalarial; antineoplastic agent; metabolite
physalin b	[no description available]	low	0	enone; lactone; organic heteroheptacyclic compound; physalin	antimalarial; antimicrobial agent; antineoplastic agent
gedunin	[no description available]	low	0	acetate ester; enone; epoxide; furans; lactone; limonoid; organic heteropentacyclic compound; pentacyclic triterpenoid	antimalarial; antineoplastic agent; Hsp90 inhibitor; plant metabolite
simalikalactone D	[no description available]	low	0	cyclic ether; delta-lactone; enone; organic heteropentacyclic compound; quassinoid; secondary alcohol; secondary alpha-hydroxy ketone; triol	antimalarial; antineoplastic agent; antiviral agent; metabolite
bromophycolide a	[no description available]	low	0	diterpenoid; macrolide; organobromine compound; phenols; tertiary alcohol	anti-HIV agent; antibacterial agent; antifungal agent; antimalarial; antineoplastic agent; metabolite
caribenol a	[no description available]	low	0	organic heterotetracyclic compound; terpene lactone; tertiary alcohol	antimalarial; antitubercular agent; metabolite
borrelidin	[no description available]	low	0	aliphatic nitrile; diol; macrolide; monocarboxylic acid; secondary alcohol	antifungal agent; antimalarial; antimicrobial agent; antineoplastic agent; apoptosis inducer; bacterial metabolite
asp3026	[no description available]	low	0	aromatic amine; diamino-1,3,5-triazine; monomethoxybenzene; N-methylpiperazine; piperidines; secondary amino compound; sulfone	antimalarial; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
leachianone a	[no description available]	low	0	4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone	antimalarial; antineoplastic agent; metabolite
physalin f	[no description available]	low	0	enone; epoxy steroid; lactone; physalin	antileishmanial agent; antimalarial; antineoplastic agent; apoptosis inducer; immunosuppressive agent
crambescidin 800	[no description available]	low	0	alkaloid; carboxylic ester; guanidines; monocarboxylic acid amide; organic heteropentacyclic compound; primary amino compound; secondary alcohol; spiro compound	anti-HIV-1 agent; anti-HSV-1 agent; antimalarial; marine metabolite
physalin g	[no description available]	low	0	6alpha-hydroxy steroid; enone; lactone; organic heteroheptacyclic compound; physalin	antimalarial
physalin d	[no description available]	low	0	5alpha-hydroxy steroid; 6beta-hydroxy steroid; cyclic ether; enone; lactone; organic heteroheptacyclic compound; physalin	antimalarial; antimycobacterial drug; antineoplastic agent
8-azahypoxanthine	[no description available]	low	0	nucleobase analogue; triazolopyrimidines	antimalarial; EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor
2,3-dihydroxybenzoic acid	[no description available]	low	0	dihydroxybenzoic acid	human xenobiotic metabolite; plant metabolite
tartronic acid	[no description available]	low	0	dicarboxylic acid; dicarboxylic fatty acid	plant metabolite
protocatechuic acid	[no description available]	low	0	catechols; dihydroxybenzoic acid	antineoplastic agent; EC 1.1.1.25 (shikimate dehydrogenase) inhibitor; EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor; human xenobiotic metabolite; plant metabolite
3-phenylpropionic acid	[no description available]	low	0	benzenes; monocarboxylic acid	antifungal agent; human metabolite; plant metabolite
4-hydroxybenzyl alcohol	[no description available]	low	0	benzyl alcohols; phenols	plant metabolite
4-hydroxyphenylacetic acid	[no description available]	low	0	monocarboxylic acid; phenols	fungal metabolite; human metabolite; mouse metabolite; plant metabolite
4-hydroxybenzoic acid	[no description available]	low	0	monohydroxybenzoic acid	algal metabolite; plant metabolite
allantoic acid	[no description available]	low	0	ureas	mouse metabolite; plant metabolite
benzaldehyde	[no description available]	low	0	benzaldehydes	EC 3.1.1.3 (triacylglycerol lipase) inhibitor; EC 3.5.5.1 (nitrilase) inhibitor; flavouring agent; fragrance; odorant receptor agonist; plant metabolite
benzoic acid	[no description available]	low	0	benzoic acids	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
betaine aldehyde	[no description available]	low	0	quaternary ammonium ion	Aspergillus metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite
cadaverine	[no description available]	low	0	alkane-alpha,omega-diamine	Daphnia magna metabolite; Escherichia coli metabolite; mouse metabolite; plant metabolite
catechol	[no description available]	low	0	catechols	allelochemical; genotoxin; plant metabolite
choline	[no description available]	low	0	cholines	allergen; Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; neurotransmitter; nutrient; plant metabolite; Saccharomyces cerevisiae metabolite
cuminol	[no description available]	low	0	benzyl alcohols; p-menthane monoterpenoid	fragrance; insect repellent; plant metabolite; volatile oil component; xenobiotic metabolite
cuminaldehyde	[no description available]	low	0	benzaldehydes	insecticide; plant metabolite; volatile oil component
4-vinylguaiacol	[no description available]	low	0	phenols	flavouring agent; pheromone; plant metabolite
4-methylumbelliferyl acetate	[no description available]	low	0	acetate ester; coumarins	plant metabolite
gallic acid	[no description available]	low	0	trihydroxybenzoic acid	antineoplastic agent; antioxidant; apoptosis inducer; astringent; cyclooxygenase 2 inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; geroprotector; human xenobiotic metabolite; plant metabolite
indoleacetamide	[no description available]	low	0	indoles; monocarboxylic acid amide; N-acylammonia	bacterial metabolite; fungal metabolite; plant metabolite
caprylic aldehyde	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	plant metabolite
n(1)-methylnicotinamide	[no description available]	low	0	pyridinium ion	algal metabolite; anti-inflammatory agent; human urinary metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
1-aminocyclopropane-1-carboxylic acid	[no description available]	low	0	amino acid zwitterion; monocarboxylic acid; non-proteinogenic alpha-amino acid	ethylene releasers; plant metabolite
3,4-dihydrocoumarin	[no description available]	low	0	chromanone	plant metabolite
homogentisic acid	[no description available]	low	0	dihydroxyphenylacetic acid; hydroquinones	human metabolite; plant metabolite
indoleacetic acid	[no description available]	low	0	indole-3-acetic acids; monocarboxylic acid	auxin; human metabolite; mouse metabolite; plant hormone; plant metabolite
indol-3-yl pyruvic acid	[no description available]	low	0	2-oxo monocarboxylic acid; indol-3-yl carboxylic acid	plant metabolite; Saccharomyces cerevisiae metabolite
melilotic acid	[no description available]	low	0	monocarboxylic acid; phenols	bacterial xenobiotic metabolite; fungal xenobiotic metabolite; human xenobiotic metabolite; plant metabolite
racemethionine	[no description available]	low	0	alpha-amino acid; amino acid zwitterion; sulfur-containing amino acid	algal metabolite; Daphnia magna metabolite; Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
n-methylphenylethanolamine	[no description available]	low	0	alkaloid; phenylethanolamines	human metabolite; plant metabolite
naphthalene	[no description available]	low	0	naphthalenes; ortho-fused bicyclic arene	apoptosis inhibitor; carcinogenic agent; environmental contaminant; mouse metabolite; plant metabolite; volatile oil component
1-octanol	[no description available]	low	0	octanol; primary alcohol	antifungal agent; bacterial metabolite; fuel additive; kairomone; plant metabolite
oxalic acid	[no description available]	low	0	alpha,omega-dicarboxylic acid	algal metabolite; human metabolite; plant metabolite
4-aminobenzoic acid	[no description available]	low	0	aminobenzoic acid; aromatic amino-acid zwitterion	allergen; Escherichia coli metabolite; plant metabolite
palmitic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite
phenylacetic acid	[no description available]	low	0	benzenes; monocarboxylic acid; phenylacetic acids	allergen; Aspergillus metabolite; auxin; EC 6.4.1.1 (pyruvate carboxylase) inhibitor; Escherichia coli metabolite; human metabolite; plant growth retardant; plant metabolite; Saccharomyces cerevisiae metabolite; toxin
prephenic acid	[no description available]	low	0	oxo dicarboxylic acid	Escherichia coli metabolite; plant metabolite
pyridoxamine	[no description available]	low	0	aminoalkylpyridine; hydroxymethylpyridine; monohydroxypyridine; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite
pyrogallol	[no description available]	low	0	benzenetriol; phenolic donor	plant metabolite
tryptamine	[no description available]	low	0	aminoalkylindole; aralkylamino compound; indole alkaloid; tryptamines	human metabolite; mouse metabolite; plant metabolite
vanillin	[no description available]	low	0	benzaldehydes; monomethoxybenzene; phenols	anti-inflammatory agent; anticonvulsant; antioxidant; flavouring agent; plant metabolite
aminopropionitrile	[no description available]	low	0	aminopropionitrile	antineoplastic agent; antirheumatic drug; collagen cross-linking inhibitor; plant metabolite
meglutol	[no description available]	low	0	3-hydroxy carboxylic acid; dicarboxylic acid; tertiary alcohol	anticholesteremic drug; antimetabolite; EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor; human metabolite; plant metabolite
methylbufotenin	[no description available]	low	0	aromatic ether; tertiary amino compound; tryptamine alkaloid	hallucinogen; plant metabolite
7,8-dihydroxyflavone	[no description available]	low	0	dihydroxyflavone	antidepressant; antineoplastic agent; antioxidant; plant metabolite; tropomyosin-related kinase B receptor agonist
anabasine	[no description available]	low	0	piperidine alkaloid; pyridine alkaloid	nicotinic acetylcholine receptor agonist; plant metabolite; teratogenic agent
acetovanillone	[no description available]	low	0	acetophenones; aromatic ketone; methyl ketone	antirheumatic drug; EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite
azelaic acid	[no description available]	low	0	alpha,omega-dicarboxylic acid; dicarboxylic fatty acid	antibacterial agent; antineoplastic agent; dermatologic drug; plant metabolite
benzyl benzoate	[no description available]	low	0	benzoate ester; benzyl ester	acaricide; plant metabolite; scabicide
5-methoxypsoralen	[no description available]	low	0	5-methoxyfurocoumarin; organic heterotricyclic compound; psoralens	hepatoprotective agent; plant metabolite
2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one	[no description available]	low	0	aromatic ether; benzoxazine; cyclic hydroxamic acid; lactol	allelochemical; plant metabolite
caffeic acid	[no description available]	low	0	catechols; hydroxycinnamic acid	antioxidant; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; EC 2.5.1.18 (glutathione transferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; plant metabolite
caffeine	[no description available]	low	0	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic
beta-glycerophosphoric acid	[no description available]	low	0	glycerol monophosphate	Escherichia coli metabolite; plant metabolite
cetyl alcohol	[no description available]	low	0	hexadecanol; long-chain primary fatty alcohol	algal metabolite; flavouring agent; human metabolite; plant metabolite
chrysanthemic acid	[no description available]	low	0	cyclopropanes; monocarboxylic acid	plant metabolite
colchicine, (+-)-isomer	[no description available]	low	0	acetamides; alkaloid; aromatic ether; carbotricyclic compound	microtubule-destabilising agent; plant metabolite
decanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; anti-inflammatory agent; antibacterial agent; human metabolite; plant metabolite; volatile oil component
benzophenone	[no description available]	low	0	benzophenones	photosensitizing agent; plant metabolite
embelin	[no description available]	low	0	dihydroxy-1,4-benzoquinones	antimicrobial agent; antineoplastic agent; hepatitis C protease inhibitor; plant metabolite
guvacine	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; beta-amino acid; pyridine alkaloid; secondary amino compound; tetrahydropyridine	GABA reuptake inhibitor; plant metabolite
indole-3-carbinol	[no description available]	low	0	indolyl alcohol	antineoplastic agent; plant metabolite
indolepropionic acid	[no description available]	low	0	indol-3-yl carboxylic acid	auxin; human metabolite; plant metabolite
beta-lapachone	[no description available]	low	0	benzochromenone; orthoquinones	anti-inflammatory agent; antineoplastic agent; plant metabolite
lauric acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; antibacterial agent; plant metabolite
methoxsalen	[no description available]	low	0	aromatic ether; psoralens	antineoplastic agent; cross-linking reagent; dermatologic drug; photosensitizing agent; plant metabolite
masoprocol	[no description available]	low	0	catechols; lignan; tetrol	antioxidant; ferroptosis inhibitor; geroprotector; plant metabolite
phloretin	[no description available]	low	0	dihydrochalcones	antineoplastic agent; plant metabolite
4-aminobenzoic acid	[no description available]	low	0	aminobenzoate; aromatic amino-acid anion	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
safrole	[no description available]	low	0	benzodioxoles	flavouring agent; insecticide; metabolite; plant metabolite
stearic acid	[no description available]	low	0	long-chain fatty acid; saturated fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; human metabolite; plant metabolite
sulforaphane	[no description available]	low	0	isothiocyanate; sulfoxide	antineoplastic agent; antioxidant; EC 3.5.1.98 (histone deacetylase) inhibitor; plant metabolite
theobromine	[no description available]	low	0	dimethylxanthine	adenosine receptor antagonist; bronchodilator agent; food component; human blood serum metabolite; mouse metabolite; plant metabolite; vasodilator agent
triacetin	[no description available]	low	0	triglyceride	adjuvant; antifungal drug; food additive carrier; food emulsifier; food humectant; fuel additive; plant metabolite; solvent
undecylenic acid	[no description available]	low	0	undecenoic acid	antifungal drug; plant metabolite
hydroxyproline	[no description available]	low	0	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite
dipropylenetriame	[no description available]	low	0	polyazaalkane	algal metabolite; plant metabolite
vincristine	[no description available]	low	0	acetate ester; formamides; methyl ester; organic heteropentacyclic compound; organic heterotetracyclic compound; tertiary alcohol; tertiary amino compound; vinca alkaloid	antineoplastic agent; drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
levodopa	[no description available]	low	0	amino acid zwitterion; dopa; L-tyrosine derivative; non-proteinogenic L-alpha-amino acid	allelochemical; antidyskinesia agent; antiparkinson drug; dopaminergic agent; hapten; human metabolite; mouse metabolite; neurotoxin; plant growth retardant; plant metabolite; prodrug
phlorhizin	[no description available]	low	0	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	antioxidant; plant metabolite
phenylalanine	[no description available]	low	0	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
asparagine	[no description available]	low	0	amino acid zwitterion; asparagine; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
n-pentanol	[no description available]	low	0	pentanol; short-chain primary fatty alcohol	human metabolite; plant metabolite
threonine	[no description available]	low	0	amino acid zwitterion; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid; threonine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
alizarin	[no description available]	low	0	dihydroxyanthraquinone	chromophore; dye; plant metabolite
tryptophan	[no description available]	low	0	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
isoleucine	[no description available]	low	0	aspartate family amino acid; isoleucine; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
ethane	[no description available]	low	0	alkane; gas molecular entity	plant metabolite; refrigerant
gibberellic acid	[no description available]	low	0	C19-gibberellin; gibberellin monocarboxylic acid; lactone; organic heteropentacyclic compound	mouse metabolite; plant metabolite
isophorone	[no description available]	low	0	cyclic ketone; enone	plant metabolite; solvent
linalool	[no description available]	low	0	monoterpenoid; tertiary alcohol	antimicrobial agent; fragrance; plant metabolite; volatile oil component
isoprene	[no description available]	low	0	alkadiene; hemiterpene; volatile organic compound	plant metabolite
isobutylamine	[no description available]	low	0	alkylamines	plant metabolite
isobutyric acid	[no description available]	low	0	branched-chain saturated fatty acid; fatty acid 4:0; methyl-branched fatty acid	Daphnia magna metabolite; plant metabolite; volatile oil component
camphene	[no description available]	low	0	carbobicyclic compound; monoterpene	fragrance; plant metabolite
alpha-pinene	[no description available]	low	0	pinene	plant metabolite
purpurin	[no description available]	low	0	trihydroxyanthraquinone	biological pigment; histological dye; plant metabolite
visnagin	[no description available]	low	0	aromatic ether; furanochromone; polyketide	anti-inflammatory agent; antihypertensive agent; EC 1.1.1.37 (malate dehydrogenase) inhibitor; phytotoxin; plant metabolite; vasodilator agent
2,6-dihydroxyanthraquinone	[no description available]	low	0	dihydroxyanthraquinone	antimutagen; plant metabolite
methyl n-methylanthranilate	[no description available]	low	0	benzoate ester; methyl ester; secondary amino compound; substituted aniline	animal metabolite; fungal metabolite; plant metabolite
2-furoic acid	[no description available]	low	0	furoic acid	bacterial xenobiotic metabolite; human xenobiotic metabolite; inhibitor; plant metabolite; Saccharomyces cerevisiae metabolite
piperitone	[no description available]	low	0	cyclic terpene ketone; p-menthane monoterpenoid	plant metabolite; volatile oil component
resacetophenone	[no description available]	low	0	dihydroxyacetophenone; resorcinols	plant metabolite
salicylaldehyde	[no description available]	low	0	hydroxybenzaldehyde	nematicide; plant metabolite
1-methylnaphthalene	[no description available]	low	0	methylnaphthalene	carcinogenic agent; plant metabolite
pseudoephedrine	[no description available]	low	0	phenylethanolamines; secondary alcohol; secondary amino compound	anti-asthmatic drug; bronchodilator agent; central nervous system drug; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
pyrogallol 1,3-dimethyl ether	[no description available]	low	0	dimethoxybenzene; phenols	plant metabolite
veratrole	[no description available]	low	0	dimethoxybenzene	plant metabolite
isatin	[no description available]	low	0	indoledione	EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
phenothiazine	[no description available]	low	0	phenothiazine	ferroptosis inhibitor; plant metabolite; radical scavenger
veratric acid	[no description available]	low	0	benzoic acids	allergen; plant metabolite
synephrine	[no description available]	low	0	ethanolamines; phenethylamine alkaloid; phenols	alpha-adrenergic agonist; plant metabolite
piperonylic acid	[no description available]	low	0	aromatic carboxylic acid; benzodioxoles; monocarboxylic acid	antifungal agent; EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor; plant metabolite; vulnerary
benzothiazole	[no description available]	low	0	benzothiazoles	environmental contaminant; plant metabolite; xenobiotic
2-methylbutanal	[no description available]	low	0	2-methyl-branched fatty aldehyde; methylbutanal	plant metabolite; Saccharomyces cerevisiae metabolite; volatile oil component
methylcyclopentane	[no description available]	low	0	cycloalkane; volatile organic compound	human metabolite; plant metabolite
phosphoribosyl pyrophosphate	[no description available]	low	0	5-O-phosphono-D-ribofuranosyl diphosphate	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite
2-methylvaleric acid	[no description available]	low	0	branched-chain saturated fatty acid; methyl-branched fatty acid; monocarboxylic acid; short-chain fatty acid	flavouring agent; fragrance; plant metabolite
ethyl 2-methylpropanoate	[no description available]	low	0	fatty acid ethyl ester	plant metabolite
3-hydroxybenzoic acid	[no description available]	low	0	monohydroxybenzoic acid	bacterial metabolite; plant metabolite
carveol	[no description available]	low	0	limonene monoterpenoid	plant metabolite; volatile oil component
methylparaben	[no description available]	low	0	paraben	antifungal agent; antimicrobial food preservative; neuroprotective agent; plant metabolite
alpha phellandrene	[no description available]	low	0	cyclohexadiene; phellandrene	antimicrobial agent; plant metabolite; volatile oil component
gamma-terpinene	[no description available]	low	0	cyclohexadiene; monoterpene	antioxidant; human xenobiotic metabolite; plant metabolite; volatile oil component
alpha-terpinene	[no description available]	low	0	cyclohexadiene; monoterpene	plant metabolite; volatile oil component
4-cymene	[no description available]	low	0	monoterpene; toluenes	human urinary metabolite; plant metabolite; volatile oil component
4-hydroxyacetophenone	[no description available]	low	0	monohydroxyacetophenone	fungal metabolite; mouse metabolite; plant metabolite
4-anisic acid	[no description available]	low	0	methoxybenzoic acid	plant metabolite
styrene	[no description available]	low	0	styrenes; vinylarene; volatile organic compound	mouse metabolite; mutagen; plant metabolite
benzylamine	[no description available]	low	0	aralkylamine; primary amine	allergen; EC 3.5.5.1 (nitrilase) inhibitor; plant metabolite
anisole	[no description available]	low	0	monomethoxybenzene	plant metabolite
phenyl ether	[no description available]	low	0	aromatic ether	plant metabolite
1,3-diphenylurea	[no description available]	low	0	phenylureas	cytokinin; plant metabolite
3-phenylpropanal	[no description available]	low	0	aldehyde; benzenes	flavouring agent; plant metabolite
2-ethylhexanol	[no description available]	low	0	primary alcohol	plant metabolite; volatile oil component
4-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
ethyl butyrate	[no description available]	low	0	butyrate ester	plant metabolite
12-hydroxy stearic acid	[no description available]	low	0	hydroxyoctadecanoic acid; secondary alcohol	bacterial xenobiotic metabolite; plant metabolite
methyl caproate	[no description available]	low	0	fatty acid methyl ester; hexanoate ester	flavouring agent; plant metabolite
propanethiol	[no description available]	low	0	alkanethiol	plant metabolite
allyl alcohol	[no description available]	low	0	primary allylic alcohol; propenol	antibacterial agent; fungicide; herbicide; insecticide; plant metabolite
isoamylamine	[no description available]	low	0	primary aliphatic amine	bacterial metabolite; plant metabolite
2-pentanone	[no description available]	low	0	methyl ketone; pentanone	plant metabolite
methylcyclohexane	[no description available]	low	0	cycloalkane; volatile organic compound	aprotic solvent; human metabolite; plant metabolite
n-pentanoic acid	[no description available]	low	0	short-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
propyl acetate	[no description available]	low	0	acetate ester	fragrance; plant metabolite
allyl cyanide	[no description available]	low	0	aliphatic nitrile; olefinic compound	antifeedant; neurotoxin; plant metabolite
ethyl formate	[no description available]	low	0	ethyl ester; formate ester	fumigant; plant metabolite
pentanal	[no description available]	low	0	saturated fatty aldehyde	plant metabolite
piperidine	[no description available]	low	0	azacycloalkane; piperidines; saturated organic heteromonocyclic parent; secondary amine	base; catalyst; human metabolite; non-polar solvent; plant metabolite; protic solvent; reagent
heptanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
1-hexanol	[no description available]	low	0	hexanol; primary alcohol	alarm pheromone; antibacterial agent; fragrance; plant metabolite
ethyl stearate	[no description available]	low	0	long-chain fatty acid ethyl ester; octadecanoate ester	plant metabolite
heptanol	[no description available]	low	0	heptanol; primary alcohol	flavouring agent; fragrance; gap junctional intercellular communication inhibitor; plant metabolite
nonane	[no description available]	low	0	alkane	plant metabolite; volatile oil component
pelargonic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; antifeedant; Daphnia magna metabolite; plant metabolite
undecan-2-one	[no description available]	low	0	dialkyl ketone; methyl ketone	plant metabolite; rodenticide
octyl acetate	[no description available]	low	0	acetate ester	plant metabolite
decanaldehyde	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	antifungal agent; fragrance; plant metabolite
n-dodecane	[no description available]	low	0	alkane	plant metabolite
undecan-1-ol	[no description available]	low	0	primary alcohol; undecanol	flavouring agent; plant metabolite
undecanal	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	antimycobacterial drug; plant metabolite; volatile oil component
dodecanol	[no description available]	low	0	dodecanol; primary alcohol	bacterial metabolite; cosmetic; insect attractant; insecticide; pheromone; plant metabolite
1-tridecanol	[no description available]	low	0	long-chain primary fatty alcohol; tridecanol	bacterial metabolite; human metabolite; plant metabolite
myristyl alcohol	[no description available]	low	0	long-chain primary fatty alcohol; tetradecanol	pheromone; plant metabolite; volatile oil component
behenic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
stearyl alcohol	[no description available]	low	0	long-chain primary fatty alcohol; octadecanol	algal metabolite; human metabolite; plant metabolite
eicosane	[no description available]	low	0	long-chain alkane	plant metabolite
3-hydroxy-3-methylbutene	[no description available]	low	0	olefinic compound; tertiary alcohol	animal metabolite; fragrance; pheromone; plant metabolite
3,4,5-trimethoxybenzoic acid	[no description available]	low	0	benzoic acids; methoxybenzenes	human urinary metabolite; human xenobiotic metabolite; plant metabolite
2-chlorobenzoic acid	[no description available]	low	0	2-halobenzoic acid; monochlorobenzoic acid	plant hormone; plant metabolite
scoparone	[no description available]	low	0	aromatic ether; coumarins	anti-allergic agent; anti-inflammatory agent; antihypertensive agent; antilipemic drug; immunosuppressive agent; plant metabolite
dimethoxyphenylethylamine	[no description available]	low	0	alkaloid; aromatic ether; phenylethylamine	allergen; plant metabolite
ethyl-p-hydroxybenzoate	[no description available]	low	0	ethyl ester; paraben	antifungal agent; antimicrobial food preservative; phytoestrogen; plant metabolite
piperonal	[no description available]	low	0	arenecarbaldehyde; benzodioxoles	fragrance; insect repellent; plant metabolite
vanillic acid	[no description available]	low	0	methoxybenzoic acid; monohydroxybenzoic acid	plant metabolite
peucedanin	[no description available]	low	0	aromatic ether; furanocoumarin; lactone	plant metabolite
indolebutyric acid	[no description available]	low	0	indol-3-yl carboxylic acid	auxin; plant hormone; plant metabolite
syringaldehyde	[no description available]	low	0	dimethoxybenzene; hydroxybenzaldehyde	hypoglycemic agent; plant metabolite
2-aminothiophenol	[no description available]	low	0	aryl thiol; substituted aniline	plant metabolite
shikimic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; cyclohexenecarboxylic acid; hydroxy monocarboxylic acid	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
estragole	[no description available]	low	0	alkenylbenzene; monomethoxybenzene; phenylpropanoid	carcinogenic agent; flavouring agent; genotoxin; insect attractant; plant metabolite
citronellol	[no description available]	low	0	monoterpenoid	plant metabolite
ethyl acetoacetate	[no description available]	low	0	ethyl ester	antibacterial agent; flavouring agent; plant metabolite
2-hydroxypyridine	[no description available]	low	0	monohydroxypyridine	plant metabolite
hexanoic acid	[no description available]	low	0	medium-chain fatty acid; straight-chain saturated fatty acid	human metabolite; plant metabolite
n-heptane	[no description available]	low	0	alkane; volatile organic compound	non-polar solvent; plant metabolite
1-nonanol	[no description available]	low	0	nonanol; primary alcohol	antifungal agent; flavouring agent; plant metabolite; volatile oil component
2-vanillin	[no description available]	low	0	benzaldehydes; guaiacols	antimutagen; plant metabolite
citronellyl acetate	[no description available]	low	0	acetate ester; monoterpenoid	plant metabolite
chrysene	[no description available]	low	0	ortho-fused polycyclic arene	plant metabolite
azulene	[no description available]	low	0	azulenes; mancude carbobicyclic parent; ortho-fused bicyclic arene	plant metabolite; volatile oil component
ephedrine	[no description available]	low	0	phenethylamine alkaloid; phenylethanolamines	bacterial metabolite; environmental contaminant; nasal decongestant; plant metabolite; sympathomimetic agent; vasoconstrictor agent; xenobiotic
pseudoephedrine hydrochloride	[no description available]	low	0	hydrochloride	plant metabolite
citrulline	[no description available]	low	0	amino acid zwitterion; citrulline	Daphnia magna metabolite; EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; protective agent; Saccharomyces cerevisiae metabolite
4-methylcatechol	[no description available]	low	0	methylcatechol	antioxidant; carcinogenic agent; hapten; human metabolite; plant metabolite
beta-erythroidine	[no description available]	low	0	delta-lactone; indole alkaloid; organic heterotetracyclic compound; tertiary amino compound	muscle relaxant; plant metabolite
glycyrrhetinic acid	[no description available]	low	0	cyclic terpene ketone; hydroxy monocarboxylic acid; pentacyclic triterpenoid	immunomodulator; plant metabolite
pinane	[no description available]	low	0	carbobicyclic compound; monoterpene; terpenoid fundamental parent	plant metabolite
naphthazarin	[no description available]	low	0	hydroxy-1,4-naphthoquinone	acaricide; antibacterial agent; antineoplastic agent; apoptosis inducer; geroprotector; plant metabolite
reticulin	[no description available]	low	0	benzylisoquinoline alkaloid; benzyltetrahydroisoquinoline; isoquinolinol	plant metabolite
cytisine	[no description available]	low	0	alkaloid; bridged compound; lactam; organic heterotricyclic compound; secondary amino compound	nicotinic acetylcholine receptor agonist; phytotoxin; plant metabolite
indole-3-carbaldehyde	[no description available]	low	0	heteroarenecarbaldehyde; indole alkaloid; indoles	bacterial metabolite; human xenobiotic metabolite; marine metabolite; plant metabolite
thymoquinone	[no description available]	low	0	1,4-benzoquinones	adjuvant; anti-inflammatory agent; antidepressant; antineoplastic agent; antioxidant; cardioprotective agent; plant metabolite
phenylpropanolamine	[no description available]	low	0	amphetamines; phenethylamine alkaloid	plant metabolite
4-hydroxyphenylethanol	[no description available]	low	0	phenols	anti-arrhythmia drug; antioxidant; cardiovascular drug; fungal metabolite; geroprotector; plant metabolite; protective agent
citronellic acid	[no description available]	low	0	medium-chain fatty acid; monoterpenoid; monounsaturated fatty acid	flavouring agent; plant metabolite
isovaleric acid	[no description available]	low	0	branched-chain saturated fatty acid; methylbutyric acid; short-chain fatty acid	mammalian metabolite; plant metabolite
iberin	[no description available]	low	0	isothiocyanate; sulfoxide	apoptosis inducer; plant metabolite; quorum sensing inhibitor
16-hydroxypalmitic acid	[no description available]	low	0	hydroxypalmitic acid; omega-hydroxy-long-chain fatty acid	plant metabolite
arachidic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
octacosanoic acid	[no description available]	low	0	straight-chain saturated fatty acid; ultra-long-chain fatty acid	plant metabolite
ascaridole	[no description available]	low	0	organic heterobicyclic compound; organic peroxide; p-menthane monoterpenoid	antileishmanial agent; antinematodal drug; plant metabolite
abietic acid	[no description available]	low	0	abietane diterpenoid; monocarboxylic acid	plant metabolite
hematoxylin	[no description available]	low	0	organic heterotetracyclic compound; oxacycle; polyphenol; tertiary alcohol	histological dye; plant metabolite
pyridoxamine dihydrochloride	[no description available]	low	0	hydrochloride; vitamin B6	Escherichia coli metabolite; human metabolite; iron chelator; mouse metabolite; nephroprotective agent; plant metabolite; Saccharomyces cerevisiae metabolite
tryptophol	[no description available]	low	0	indolyl alcohol	auxin; plant metabolite; Saccharomyces cerevisiae metabolite
hemimellitene	[no description available]	low	0	trimethylbenzene	neurotoxin; plant metabolite
2-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
syringic acid	[no description available]	low	0	benzoic acids; dimethoxybenzene; phenols	plant metabolite
6-methoxybenzoxazolinone	[no description available]	low	0	aromatic ether; benzoxazole	antibacterial agent; anticonvulsant; antifungal agent; muscle relaxant; plant metabolite
1,1-dimethoxyethane	[no description available]	low	0	acetal; diether	flavouring agent; plant metabolite
2-methylfuran	[no description available]	low	0	furans; volatile organic compound	flavouring agent; fuel; hepatotoxic agent; human urinary metabolite; plant metabolite
perillyl alcohol	[no description available]	low	0	limonene monoterpenoid	plant metabolite; volatile oil component
cumic acid	[no description available]	low	0	cumic acid	plant metabolite
tricaprylin	[no description available]	low	0	octanoate ester; triglyceride	anticonvulsant; plant metabolite
senecioic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; methyl-branched fatty acid; monounsaturated fatty acid; short-chain fatty acid	plant metabolite
3-hexen-1-ol	[no description available]	low	0	alkenyl alcohol; homoallylic alcohol; primary alcohol; volatile organic compound	plant metabolite
n-hexadecane	[no description available]	low	0	long-chain alkane	non-polar solvent; plant metabolite; volatile oil component
beta-phellandrene	[no description available]	low	0	phellandrene	plant metabolite
tristearin	[no description available]	low	0	triacylglycerol 54:0	Caenorhabditis elegans metabolite; plant metabolite
lignoceric acid	[no description available]	low	0	straight-chain saturated fatty acid; very long-chain fatty acid	Daphnia tenebrosa metabolite; human metabolite; plant metabolite; volatile oil component
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol	[no description available]	low	0	terpineol; tertiary alcohol	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; antiparasitic agent; apoptosis inducer; plant metabolite; volatile oil component
6-methylsalicylic acid	[no description available]	low	0	monohydroxybenzoic acid	Penicillium metabolite; plant metabolite
1-phenyl-1,2-propanedione	[no description available]	low	0	alpha-diketone; aromatic ketone	plant metabolite
2-methylcyclohexanone	[no description available]	low	0	cyclohexanones	flavouring agent; plant metabolite
terpinolene	[no description available]	low	0	p-menthadiene	insect repellent; plant metabolite; sedative; volatile oil component
isovalerylaldehyde	[no description available]	low	0	methylbutanal	flavouring agent; plant metabolite; Saccharomyces cerevisiae metabolite; volatile oil component
levulinic acid	[no description available]	low	0	oxopentanoic acid; straight-chain saturated fatty acid	plant metabolite
2-tridecanone	[no description available]	low	0	methyl ketone	flavouring agent; plant metabolite
octadecane	[no description available]	low	0	long-chain alkane	bacterial metabolite; plant metabolite
dimethylselenide	[no description available]	low	0	organoselenium compound	bacterial xenobiotic metabolite; plant metabolite
chorismic acid	[no description available]	low	0	5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid	Escherichia coli metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
2-methyl-5-(1-methylethenyl)cyclohexanol	[no description available]	low	0	p-menthane monoterpenoid; secondary alcohol	acaricide; plant metabolite; volatile oil component
4-carboxybenzaladehyde	[no description available]	low	0	benzaldehydes; benzoic acids; monocarboxylic acid	plant metabolite
3-methylbenzaldehyde	[no description available]	low	0	tolualdehyde	plant metabolite
isovanillin	[no description available]	low	0	benzaldehydes; monomethoxybenzene; phenols	animal metabolite; antidiarrhoeal drug; antifungal agent; EC 1.2.3.1 (aldehyde oxidase) inhibitor; HIV protease inhibitor; plant metabolite
2,5-dimethylfuran	[no description available]	low	0	furans	antifungal agent; bacterial metabolite; fuel; fumigant; human urinary metabolite; Maillard reaction product; plant metabolite
2-hexanol	[no description available]	low	0	hexanol; secondary alcohol	human metabolite; plant metabolite; semiochemical
ethyl palmitate	[no description available]	low	0	hexadecanoate ester; long-chain fatty acid ethyl ester	plant metabolite
2-nonanol	[no description available]	low	0	nonanol; secondary alcohol	bacterial metabolite; flavouring agent; pheromone; plant metabolite; rat metabolite; volatile oil component
n-propyl disulfide	[no description available]	low	0	organic disulfide	plant metabolite
tridecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
n-tetradecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
pentadecane	[no description available]	low	0	long-chain alkane	animal metabolite; plant metabolite; volatile oil component
heptadecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
nonadecane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
n-heneicosane	[no description available]	low	0	long-chain alkane	pheromone; plant metabolite; volatile oil component
docosane	[no description available]	low	0	long-chain alkane	plant metabolite
octacosane	[no description available]	low	0	long-chain alkane	plant metabolite
nonacosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
bulbocapnine	[no description available]	low	0	aporphine alkaloid; aromatic ether; oxacycle; phenols	EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor; EC 1.4.3.22 (diamine oxidase) inhibitor; plant metabolite
1,2,3-trimethoxybenzene	[no description available]	low	0	methoxybenzenes	plant metabolite
2-pyrrolecarboxylic acid	[no description available]	low	0	pyrrolecarboxylic acid	plant metabolite
tridecanoic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
n-tricosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
2-propylphenol	[no description available]	low	0	phenols	flavouring agent; plant metabolite
isovanillic acid	[no description available]	low	0	methoxybenzoic acid; monohydroxybenzoic acid	antibacterial agent; plant metabolite
tetracosane	[no description available]	low	0	long-chain alkane	plant metabolite; volatile oil component
docosanol	[no description available]	low	0	docosanol; long-chain primary fatty alcohol	antiviral drug; plant metabolite
2-methylpyrrolidine	[no description available]	low	0	pyrrolidines	plant metabolite
2-nonanone	[no description available]	low	0	methyl ketone	plant metabolite
ethyl gallate	[no description available]	low	0	gallate ester	plant metabolite
3-methylfuran	[no description available]	low	0	furans; volatile organic compound	Aspergillus metabolite; environmental contaminant; fungal metabolite; Penicillium metabolite; plant metabolite
pentadecanoic acid	[no description available]	low	0	long-chain fatty acid; straight-chain saturated fatty acid	algal metabolite; Daphnia magna metabolite; food component; human blood serum metabolite; plant metabolite
dihydroferulic acid	[no description available]	low	0	guaiacols; monocarboxylic acid; phenylpropanoid	antioxidant; human xenobiotic metabolite; mouse metabolite; plant metabolite
fenchone, (+-)-isomer	[no description available]	low	0	carbobicyclic compound; cyclic terpene ketone; fenchane monoterpenoid	plant metabolite
beta-pinene	[no description available]	low	0	pinene	plant metabolite
d-alpha tocopherol	[no description available]	low	0	alpha-tocopherol	algal metabolite; antiatherogenic agent; anticoagulant; antioxidant; antiviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunomodulator; micronutrient; nutraceutical; plant metabolite
selenomethionine	[no description available]	low	0	selenoamino acid; selenomethionines	plant metabolite
1-pentene-3-one	[no description available]	low	0	enone	flavouring agent; genotoxin; human metabolite; plant metabolite
dodecyldimethylamine oxide	[no description available]	low	0	tertiary amine oxide	detergent; plant metabolite
2-undecanol	[no description available]	low	0	secondary alcohol; undecanol	animal metabolite; flavouring agent; pheromone; plant metabolite; volatile oil component
digoxigenin	[no description available]	low	0	12beta-hydroxy steroid; 14beta-hydroxy steroid; 3beta-hydroxy steroid; 3beta-sterol	hapten; plant metabolite
heliamine	[no description available]	low	0	aromatic ether; diether; isoquinoline alkaloid; isoquinolines	plant metabolite
6h-dibenzo-(b,d)-pyran-6-one	[no description available]	low	0	benzochromenone	plant metabolite
diallyl disulfide	[no description available]	low	0	organic disulfide	antifungal agent; antineoplastic agent; plant metabolite
glaucine	[no description available]	low	0	aporphine alkaloid; organic heterotetracyclic compound; polyether; tertiary amino compound	antibacterial agent; antineoplastic agent; antitussive; muscle relaxant; NF-kappaB inhibitor; plant metabolite; platelet aggregation inhibitor; rat metabolite
dihydroconiferyl alcohol	[no description available]	low	0	eugenol; primary alcohol	plant metabolite
propyl benzoate	[no description available]	low	0	benzoate ester	antimicrobial food preservative; flavouring agent; plant metabolite
2-methoxy-1,4-naphthoquinone	[no description available]	low	0	1,4-naphthoquinones; enol ether	antimicrobial agent; metabolite; plant metabolite
tricosanoic acid	[no description available]	low	0	straight-chain saturated fatty acid; very long-chain fatty acid	Daphnia magna metabolite; human metabolite; plant metabolite
alpha-terpineol	[no description available]	low	0	terpineol	plant metabolite
acetosyringone	[no description available]	low	0	acetophenones; dimethoxybenzene; phenols	anti-asthmatic drug; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite
pentadecanal	[no description available]	low	0	2,3-saturated fatty aldehyde; long-chain fatty aldehyde	antimicrobial agent; plant metabolite; volatile oil component
2-ethylfuran	[no description available]	low	0	furans; volatile organic compound	bacterial metabolite; fragrance; Maillard reaction product; plant metabolite
sabinene	[no description available]	low	0	thujene	plant metabolite
n-butylbenzenesulfonamide	[no description available]	low	0	sulfonamide	neurotoxin; plant metabolite
furaneol	[no description available]	low	0	cyclic ketone; enol; furans	flavouring agent; fragrance; plant metabolite
methyl vanillate	[no description available]	low	0	aromatic ether; benzoate ester; phenols	antioxidant; plant metabolite
2-octanol	[no description available]	low	0	octanol; secondary alcohol	plant metabolite; volatile oil component
5-methoxyindole-2-carboxylic acid	[no description available]	low	0	aromatic ether; indolecarboxylic acid	EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor; hypoglycemic agent; plant metabolite
canadine, (s)-isomer	[no description available]	low	0	an (S)-7,8,13,14-tetrahydroprotoberberine; canadine	plant metabolite
14-methylhexadecanoic acid	[no description available]	low	0	branched-chain saturated fatty acid; long-chain fatty acid; methyl-branched fatty acid	mammalian metabolite; plant metabolite
dimethyldiselenide	[no description available]	low	0	organoselenium compound	bacterial metabolite; human xenobiotic metabolite; mammalian metabolite; plant metabolite
camptothecin	[no description available]	low	0	delta-lactone; pyranoindolizinoquinoline; quinoline alkaloid; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; genotoxin; plant metabolite
isopentenyladenosine	[no description available]	low	0	N-ribosyl-N(6)-isopentenyladenine; nucleoside analogue	antineoplastic agent; plant growth regulator; plant metabolite
s-methylcysteine	[no description available]	low	0	S-alkyl-L-cysteine zwitterion; S-alkyl-L-cysteine	human urinary metabolite; plant metabolite
dihydrocarvone	[no description available]	low	0	dihydrocarvones	plant metabolite
marmesin, (r)-isomer	[no description available]	low	0	marmesin	plant metabolite; rat metabolite; xenobiotic metabolite
4-hydroxybenzylcyanide	[no description available]	low	0	hydroxynitrile	plant metabolite
2,3,5-trimethylpyrazine	[no description available]	low	0	pyrazines	animal metabolite; bacterial metabolite; flavouring agent; pheromone; plant metabolite
tetradecanoylphorbol acetate	[no description available]	low	0	acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester	antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator
2,4-dihydroxy-1,4-benzoxazin-3-one	[no description available]	low	0	benzoxazine; cyclic hydroxamic acid; lactol	allelochemical; herbicide; phytotoxin; plant metabolite
precocene i	[no description available]	low	0	aromatic ether; chromenes	plant metabolite; precocenes
1-deoxynojirimycin	[no description available]	low	0	2-(hydroxymethyl)piperidine-3,4,5-triol; piperidine alkaloid	anti-HIV agent; anti-obesity agent; bacterial metabolite; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; plant metabolite
neohesperidin dihydrochalcone	[no description available]	low	0	dihydrochalcones; disaccharide derivative; neohesperidoside	environmental contaminant; plant metabolite; sweetening agent; xenobiotic
zingerone	[no description available]	low	0	methyl ketone; monomethoxybenzene; phenols	anti-inflammatory agent; antiemetic; antioxidant; flavouring agent; fragrance; plant metabolite; radiation protective agent
4-anisaldehyde	[no description available]	low	0	benzaldehydes	bacterial metabolite; human urinary metabolite; insect repellent; plant metabolite
myrcene	[no description available]	low	0	monoterpene	anabolic agent; anti-inflammatory agent; flavouring agent; fragrance; plant metabolite; volatile oil component
diacetone alcohol	[no description available]	low	0	beta-hydroxy ketone	plant metabolite
methyl tetradecanoate	[no description available]	low	0	fatty acid methyl ester	flavouring agent; fragrance; plant metabolite
nonanal	[no description available]	low	0	medium-chain fatty aldehyde; n-alkanal; saturated fatty aldehyde	human metabolite; plant metabolite
tetradecanal	[no description available]	low	0	2,3-saturated fatty aldehyde; long-chain fatty aldehyde	bacterial metabolite; plant metabolite
silybin	[no description available]	low	0	aromatic ether; benzodioxine; flavonolignan; polyphenol; secondary alpha-hydroxy ketone	antineoplastic agent; antioxidant; hepatoprotective agent; plant metabolite
oxypeucadanin, (s)-(-)-isomer	[no description available]	low	0	epoxide; furanocoumarin; lactone	plant metabolite
amygdalin	[no description available]	low	0	cyanogenic glycoside; disaccharide derivative; gentiobioside	plant metabolite
colforsin	[no description available]	low	0	acetate ester; cyclic ketone; labdane diterpenoid; organic heterotricyclic compound; tertiary alpha-hydroxy ketone; triol	adenylate cyclase agonist; anti-HIV agent; antihypertensive agent; plant metabolite; platelet aggregation inhibitor; protein kinase A agonist
swainsonine	[no description available]	medium	0	indolizidine alkaloid	antineoplastic agent; EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor; immunological adjuvant; plant metabolite
vanillyl alcohol	[no description available]	low	0	benzyl alcohols; guaiacols	plant metabolite
allyl methyl disulfide	[no description available]	low	0	organic disulfide	plant metabolite; volatile oil component
octyl glucoside	[no description available]	low	0	beta-D-glucoside	plant metabolite
dihydrochalcone	[no description available]	low	0	dihydrochalcones	plant metabolite
ursolic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid	geroprotector; plant metabolite
calanolide a	[no description available]	low	0	cyclic ether; delta-lactone; organic heterotetracyclic compound; secondary alcohol	HIV-1 reverse transcriptase inhibitor; plant metabolite
aica ribonucleotide	[no description available]	low	0	1-(phosphoribosyl)imidazolecarboxamide; aminoimidazole	cardiovascular drug; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
salvin	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; catechols; monocarboxylic acid	angiogenesis modulating agent; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; food preservative; HIV protease inhibitor; plant metabolite
obtusifoliol	[no description available]	low	0	14alpha-methyl steroid; 3beta-sterol	mouse metabolite; plant metabolite
baccatin iii	[no description available]	low	0	acetate ester; benzoate ester; tetracyclic diterpenoid	plant metabolite
secoisolariciresinol	[no description available]	low	0	secoisolariciresinol	antidepressant; phytoestrogen; plant metabolite
solanidine	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; solanid-5-en-3-ol; steroid alkaloid fundamental parent	plant metabolite; toxin
valerophenone	[no description available]	low	0	aromatic ketone	plant metabolite; volatile oil component
2,4,6-trihydroxyacetophenone	[no description available]	low	0	aromatic ketone; benzenetriol; methyl ketone	MALDI matrix material; plant metabolite
tangeretin	[no description available]	low	0	pentamethoxyflavone	antineoplastic agent; plant metabolite
djenkolic acid	[no description available]	low	0	dithioacetal; L-cysteine derivative; non-proteinogenic L-alpha-amino acid	plant metabolite; toxin
1-hexacosanol	[no description available]	low	0	hexacosanol; very long-chain primary fatty alcohol	insecticide; plant metabolite
actinidine	[no description available]	low	0	cyclopentapyridine; pyridine alkaloid	pheromone; plant metabolite
7-methylxanthine	[no description available]	low	0	oxopurine; purine alkaloid	human xenobiotic metabolite; mouse metabolite; plant metabolite
1-octacosanol	[no description available]	low	0	fatty alcohol 28:0; ultra-long-chain primary fatty alcohol	plant metabolite
suberosin	[no description available]	low	0	aromatic ether; coumarins	anticoagulant; plant metabolite
isoscopoletin	[no description available]	low	0	aromatic ether; hydroxycoumarin	plant metabolite
methyl syringate	[no description available]	low	0	benzoate ester; dimethoxybenzene; phenols	plant metabolite
gallocatechol	[no description available]	low	0	catechin; flavan-3,3',4',5,5',7-hexol	antioxidant; food component; plant metabolite
sesamin	[no description available]	low	0	benzodioxoles; furofuran; lignan	antineoplastic agent; neuroprotective agent; plant metabolite
tetrahydroalstonine	[no description available]	low	0	methyl ester; organic heteropentacyclic compound; yohimban alkaloid	plant metabolite
picropodophyllin	[no description available]	low	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antineoplastic agent; insulin-like growth factor receptor 1 antagonist; plant metabolite; tyrosine kinase inhibitor
alantolactone	[no description available]	low	0	naphthofuran; olefinic compound; sesquiterpene lactone	antineoplastic agent; apoptosis inducer; plant metabolite
kaurenoic acid	[no description available]	low	0	ent-kaurane diterpenoid	anti-HIV-1 agent; antineoplastic agent; plant metabolite
beta-amyrin	[no description available]	low	0	pentacyclic triterpenoid; secondary alcohol	Aspergillus metabolite; plant metabolite
xanthomicrol	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	antineoplastic agent; plant metabolite
voacamine	[no description available]	low	0	alkaloid ester; methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; plant metabolite
isoalantolactone	[no description available]	low	0	eudesmane sesquiterpenoid; sesquiterpene lactone	antifungal agent; apoptosis inducer; plant metabolite
hederagenin	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid; sapogenin	plant metabolite
magnoflorine	[no description available]	low	0	aporphine alkaloid; quaternary ammonium ion	plant metabolite
brazilin	[no description available]	low	0	catechols; organic heterotetracyclic compound; tertiary alcohol	anti-inflammatory agent; antibacterial agent; antineoplastic agent; antioxidant; apoptosis inducer; biological pigment; hepatoprotective agent; histological dye; NF-kappaB inhibitor; plant metabolite
strychnine n-oxide	[no description available]	low	0	monoterpenoid indole alkaloid; organic heteroheptacyclic compound; tertiary amine oxide	plant metabolite
pinoresinol	[no description available]	low	0	pinoresinol	hypoglycemic agent; phytoestrogen; plant metabolite
dauricine	[no description available]	low	0	aromatic ether; bisbenzylisoquinoline alkaloid; isoquinolines; phenols; tertiary amino compound	plant metabolite
madecassic acid	[no description available]	low	0	monocarboxylic acid; pentacyclic triterpenoid; tetrol	antioxidant; plant metabolite
uvaretin	[no description available]	low	0	aromatic ether; dihydrochalcones; polyketide; resorcinol	antineoplastic agent; plant metabolite
sakuranetin	[no description available]	low	0	(2S)-flavan-4-one; 4'-hydroxyflavanones; dihydroxyflavanone; flavonoid phytoalexin; monomethoxyflavanone	antimycobacterial drug; plant metabolite
indole-5-carboxylic acid	[no description available]	low	0	indolecarboxylic acid	plant metabolite
1,3,7,9-tetramethyluric acid	[no description available]	low	0	oxopurine; purine alkaloid	analgesic; anti-inflammatory agent; human xenobiotic metabolite; plant metabolite
phenylalanylleucine	[no description available]	low	0	dipeptide zwitterion; dipeptide	plant metabolite
ethyl protocatechuate	[no description available]	low	0	catechols; ethyl ester	antibacterial agent; antioxidant; apoptosis inducer; EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor; plant metabolite
3,5-dimethoxytoluene	[no description available]	low	0	methoxybenzenes; toluenes	fragrance; plant metabolite
methylthioethanol	[no description available]	low	0	aliphatic sulfide; primary alcohol	plant metabolite; xenobiotic metabolite
alpha-bergamotene	[no description available]	low	0	bridged compound; polycyclic olefin; sesquiterpene	plant metabolite; volatile oil component
4-methyl-4-sulfanylpentan-2-one	[no description available]	low	0	alkanethiol; methyl ketone	plant metabolite; Saccharomyces cerevisiae metabolite
5,7-dimethoxyflavone	[no description available]	low	0	dimethoxyflavone	plant metabolite
nicotine	[no description available]	low	0	3-(1-methylpyrrolidin-2-yl)pyridine	anxiolytic drug; biomarker; immunomodulator; mitogen; neurotoxin; nicotinic acetylcholine receptor agonist; peripheral nervous system drug; phytogenic insecticide; plant metabolite; psychotropic drug; teratogenic agent; xenobiotic
loganic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; cyclopentapyran; glucoside	plant metabolite
friedelin	[no description available]	low	0	cyclic terpene ketone; pentacyclic triterpenoid	anti-inflammatory drug; antipyretic; non-narcotic analgesic; plant metabolite
cholest-4-en-3-one	[no description available]	low	0	3-oxo-Delta(4) steroid; cholestanoid	human metabolite; plant metabolite
delta-tocopherol	[no description available]	low	0	tocopherol; vitamin E	food antioxidant; plant metabolite
cycloartenol	[no description available]	low	0	3beta-sterol; pentacyclic triterpenoid; phytosterols	plant metabolite
beta-peltatin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; organic heterotetracyclic compound; phenols	antineoplastic agent; plant metabolite
elemol	[no description available]	low	0	olefinic compound; sesquiterpenoid; tertiary alcohol	fragrance; plant metabolite
spathulenol	[no description available]	low	0	carbotricyclic compound; olefinic compound; sesquiterpenoid; tertiary alcohol	anaesthetic; plant metabolite; vasodilator agent; volatile oil component
mor-14	[no description available]	low	0	hydroxypiperidine; piperidine alkaloid; tertiary amino compound	anti-HIV agent; cardioprotective agent; EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite
vestitol	[no description available]	low	0	aromatic ether; hydroxyisoflavans; methoxyisoflavan	anti-inflammatory agent; phytoalexin; plant metabolite
gamma-tocopherol	[no description available]	low	0	tocopherol; vitamin E	algal metabolite; food antioxidant; plant metabolite
orotidine	[no description available]	low	0	nucleoside; pyrimidinemonocarboxylic acid; uridines	bacterial metabolite; fungal metabolite; plant metabolite
sugiol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; cyclic terpene ketone; meroterpenoid; phenols	antineoplastic agent; antioxidant; antiviral agent; plant metabolite; radical scavenger
erythrose	[no description available]	low	0	erythrose	plant metabolite
24-methylene cycloartanol	[no description available]	low	0	3beta-hydroxy steroid; pentacyclic triterpenoid	plant metabolite
panose	[no description available]	low	0	trisaccharide	plant metabolite
bursehernin	[no description available]	low	0	aromatic ether; benzodioxoles; butan-4-olide; lignan	plant metabolite
sesaminol	[no description available]	low	0	benzodioxoles; furofuran; organic hydroxy compound	antioxidant; plant metabolite
4',5,6,7-tetramethoxyflavone	[no description available]	low	0	tetramethoxyflavone	antimutagen; plant metabolite
gardenin b	[no description available]	low	0	monohydroxyflavone; tetramethoxyflavone	plant metabolite
quercetin 5,7,3',4'-tetramethyl ether	[no description available]	low	0	flavonols; tetramethoxyflavone	plant metabolite
1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid	[no description available]	low	0	alpha-amino acid; aromatic amino acid; beta-carboline alkaloid	human urinary metabolite; human xenobiotic metabolite; plant metabolite; rat metabolite
sarsasapogenin, (3beta,5alpha,25r)-isomer	[no description available]	low	0	sapogenin	gout suppressant; plant metabolite
syringaresinol	[no description available]	low	0	aromatic ether; furofuran; lignan; polyether; polyphenol	plant metabolite
cyclolaudenol	[no description available]	low	0	3beta-hydroxy steroid; pentacyclic triterpenoid	plant metabolite
galgravin	[no description available]	low	0	aryltetrahydrofuran; dimethoxybenzene; lignan; ring assembly	bone density conservation agent; neuroprotective agent; plant metabolite; platelet aggregation inhibitor
erythrodiol	[no description available]	low	0	diol; pentacyclic triterpenoid; primary alcohol; secondary alcohol	plant metabolite
6,6-dimethyl-2-methylenebicyclo(3.1.1)heptan-3-ol	[no description available]	low	0	carbobicyclic compound; pinane monoterpenoid; secondary alcohol	GABA modulator; mouse metabolite; plant metabolite; volatile oil component
selenomethionine	[no description available]	low	0	amino acid zwitterion; selenomethionine	plant metabolite
deguelin	[no description available]	low	0	aromatic ether; diether; organic heteropentacyclic compound; rotenones	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor; plant metabolite
1,9-dideoxyforskolin	[no description available]	low	0	acetate ester; labdane diterpenoid; organic heterotricyclic compound	plant metabolite
triptolide	[no description available]	low	0	diterpenoid; epoxide; gamma-lactam; organic heteroheptacyclic compound	antispermatogenic agent; plant metabolite
indospicine	[no description available]	low	0	carboxamidine; non-proteinogenic L-alpha-amino acid	hepatotoxic agent; plant metabolite
cafestol	[no description available]	low	0	diterpenoid; furans; organic heteropentacyclic compound; primary alcohol; tertiary alcohol	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; plant metabolite
nimbin	[no description available]	low	0	acetate ester; cyclic terpene ketone; enone; furans; limonoid; methyl ester; tetracyclic triterpenoid	pesticide; plant metabolite
neoeriocitrin	[no description available]	low	0	4'-hydroxyflavanones; disaccharide derivative; flavanone glycoside; neohesperidoside; trihydroxyflavanone	plant metabolite
kahweol	[no description available]	low	0	diterpenoid; furans; organic heteropentacyclic compound; primary alcohol; tertiary alcohol	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; plant metabolite
valerates	[no description available]	low	0	short-chain fatty acid anion; straight-chain saturated fatty acid anion	plant metabolite
liquiritigenin	[no description available]	low	0	4',7-dihydroxyflavanone	hormone agonist; plant metabolite
s-sulphocysteine	[no description available]	low	0	organic thiosulfate; S-substituted L-cysteine	human metabolite; plant metabolite
megestrol acetate	[no description available]	low	0	bridged compound; organic heterotetracyclic compound; secondary alcohol; sesquiterpene lactone; spiro compound; tertiary alcohol; tetrol	GABA antagonist; neurotoxin; phytogenic insecticide; plant metabolite
stachydrine	[no description available]	low	0	alkaloid; amino-acid betaine; N-methyl-L-alpha-amino acid	food component; human blood serum metabolite; plant metabolite
echinuline	[no description available]	low	0	2,5-diketopiperazines; indole alkaloid; indoles; olefinic compound	Aspergillus metabolite; marine metabolite; plant metabolite
cubebin	[no description available]	low	0	benzodioxoles; cyclic acetal; lactol; lignan; secondary alcohol	analgesic; anti-inflammatory agent; antimicrobial agent; histamine antagonist; plant metabolite; trypanocidal drug
1'-acetoxychavicol acetate	[no description available]	low	0	acetate ester; phenylpropanoid	antineoplastic agent; NF-kappaB inhibitor; plant metabolite
hydrangenol	[no description available]	low	0	dihydroisocoumarins; phenols	anti-allergic agent; plant metabolite
matairesinol	[no description available]	low	0	gamma-lactone; lignan; polyphenol	angiogenesis inhibitor; anti-asthmatic agent; phytoestrogen; plant metabolite
astilbin	[no description available]	low	0	3'-hydroxyflavanones; 4'-hydroxyflavanones; alpha-L-rhamnoside; flavanone glycoside; monosaccharide derivative; tetrahydroxyflavanone	anti-inflammatory agent; plant metabolite; radical scavenger
ginsenoside rh2	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; bone density conservation agent; cardioprotective agent; hepatoprotective agent; plant metabolite
mannopine	[no description available]	low	0	amino acid opine; dicarboxylic acid monoamide; hexitol derivative; L-glutamine derivative; non-proteinogenic L-alpha-amino acid; secondary amino compound	plant metabolite
ribulose-1,5 diphosphate	[no description available]	low	0	ribulose phosphate	Escherichia coli metabolite; plant metabolite
swertisin	[no description available]	low	0	dihydroxyflavone; flavone C-glycoside; monomethoxyflavone; monosaccharide derivative; polyphenol	adenosine A1 receptor antagonist; anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite
senegalensin	[no description available]	low	0	(2S)-flavan-4-one; 4'-hydroxyflavanones; trihydroxyflavanone	antibacterial agent; plant metabolite
glabranin	[no description available]	low	0	(2S)-flavan-4-one; dihydroxyflavanone	plant metabolite
rubiadin	[no description available]	low	0	dihydroxyanthraquinone	antibacterial agent; antioxidant; hepatoprotective agent; plant metabolite
soranjidiol	[no description available]	low	0	dihydroxyanthraquinone	antibacterial agent; plant metabolite
skullcapflavone ii	[no description available]	low	0	dihydroxyflavone; tetramethoxyflavone	anti-asthmatic drug; plant metabolite
rubimaillin	[no description available]	low	0	benzochromene; methyl ester; phenols	acyl-CoA:cholesterol acyltransferase 2 inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; neuroprotective agent; NF-kappaB inhibitor; plant metabolite
tiglic acid	[no description available]	low	0	2-methylbut-2-enoic acid	plant metabolite
psorospermin	[no description available]	low	0	epoxide; organic heterotetracyclic compound; xanthones	antineoplastic agent; plant metabolite
delphinidin	[no description available]	low	0	5-hydroxyanthocyanidin	antineoplastic agent; biological pigment; plant metabolite
sinensetin	[no description available]	low	0	pentamethoxyflavone	plant metabolite
n-methylserotonin	[no description available]	low	0	phenols; tryptamines	human metabolite; plant metabolite
lyxonic acid	[no description available]	low	0	lyxonic acid	plant metabolite
kolaviron	[no description available]	low	0	4'-methoxyflavanones; biflavonoid; dihydroflavonols; ring assembly; secondary alpha-hydroxy ketone	hepatoprotective agent; plant metabolite
spinosin	[no description available]	low	0	dihydroxyflavone; flavone C-glycoside; monomethoxyflavone	anxiolytic drug; plant metabolite
schizandrin b	[no description available]	low	0	aromatic ether; cyclic acetal; organic heterotetracyclic compound; oxacycle; tannin	anti-asthmatic agent; anti-inflammatory agent; antilipemic drug; antioxidant; apoptosis inhibitor; hepatoprotective agent; nephroprotective agent; neuroprotective agent; plant metabolite
acrovestone	[no description available]	low	0	acetophenones; aromatic ether; olefinic compound; polyphenol	antioxidant; EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
cirsiliol	[no description available]	low	0	dimethoxyflavone; trihydroxyflavone	plant metabolite
isosakuranetin	[no description available]	low	0	(2S)-flavan-4-one; 4'-methoxyflavanones; dihydroxyflavanone; monomethoxyflavanone	plant metabolite
matteucinol	[no description available]	low	0	4'-methoxyflavanones; dihydroxyflavanone; monomethoxyflavanone	plant metabolite; radical scavenger
guvacoline	[no description available]	low	0	alpha,beta-unsaturated carboxylic ester; beta-amino acid ester; enoate ester; methyl ester; pyridine alkaloid; secondary amino compound; tetrahydropyridine	muscarinic agonist; plant metabolite
corytuberine	[no description available]	low	0	aporphine alkaloid; aromatic ether; organic heterotetracyclic compound; polyphenol; tertiary amino compound	plant metabolite
actinodaphine	[no description available]	low	0	aporphine alkaloid; aromatic ether; organic heteropentacyclic compound; phenols; secondary amino compound	antibacterial agent; antifungal agent; antineoplastic agent; apoptosis inducer; plant metabolite; platelet aggregation inhibitor; topoisomerase inhibitor
ar-turmerone	[no description available]	low	0	enone; sesquiterpenoid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; plant metabolite
isolariciresinol	[no description available]	low	0	guaiacols; lignan; polyphenol; primary alcohol	plant metabolite
4'-demethyldesoxypodophyllotoxin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes; phenols	antineoplastic agent; antioxidant; immunosuppressive agent; plant metabolite
t-cadinol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	plant metabolite; volatile oil component
1-hydroxy-2-methylanthraquinone	[no description available]	low	0	monohydroxyanthraquinone	plant metabolite
nevadensin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
salvigenin	[no description available]	low	0	monohydroxyflavone; trimethoxyflavone	antilipemic drug; antineoplastic agent; apoptosis inhibitor; autophagy inducer; hypoglycemic agent; immunomodulator; neuroprotective agent; plant metabolite
secologanin	[no description available]	low	0	aldehyde; beta-D-glucoside; enoate ester; methyl ester; pyrans; secoiridoid glycoside	plant metabolite
columbianetin acetate	[no description available]	low	0	acetate ester; furanocoumarin	plant metabolite
maprounic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid	HIV-1 reverse transcriptase inhibitor; plant metabolite
acetyl aleuritolic acid	[no description available]	low	0	acetate ester; monocarboxylic acid; pentacyclic triterpenoid	antineoplastic agent; plant metabolite
myricanone	[no description available]	low	0	aromatic ether; cyclic ketone; diarylheptanoid; methoxybenzenes; phenols	antineoplastic agent; plant metabolite
glycyrrhetyl 3-monoglucuronide	[no description available]	low	0	beta-D-glucosiduronic acid; enone; monosaccharide derivative; oxo dicarboxylic acid; pentacyclic triterpenoid; triterpenoid saponin	anti-allergic agent; EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor; human xenobiotic metabolite; plant metabolite; sweetening agent
hydroxysitosterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 7alpha-hydroxy steroid	metabolite; plant metabolite
capsidiol	[no description available]	low	0	eremophilane sesquiterpenoid; octahydronaphthalenes; sesquiterpene phytoalexin	antifungal agent; plant metabolite
phaseollin (isoflavan)	[no description available]	low	0	hydroxyisoflavans	plant metabolite
cirsilineol	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	antineoplastic agent; plant metabolite
secoxyloganin	[no description available]	low	0	beta-D-glucoside; dicarboxylic acid monoester; enoate ester; methyl ester; monosaccharide derivative; pyrans; secoiridoid glycoside	anti-allergic agent; antioxidant; plant metabolite
sclareol	[no description available]	low	0	labdane diterpenoid	antifungal agent; antimicrobial agent; apoptosis inducer; fragrance; plant metabolite
butrin	[no description available]	low	0	4'-hydroxyflavanones; flavanone glycoside; monohydroxyflavanone	anti-inflammatory agent; plant metabolite
diplopterol	[no description available]	low	0	hopanoid; pentacyclic triterpenoid; tertiary alcohol	plant metabolite
confertin	[no description available]	low	0	cyclic ketone; gamma-lactone; organic heterotricyclic compound; pseudoguaianolide	anti-inflammatory agent; metabolite; plant metabolite
pluviatolide	[no description available]	low	0	aromatic ether; benzodioxoles; butan-4-olide; lignan; phenols	plant metabolite
albicanol	[no description available]	low	0	carbobicyclic compound; homoallylic alcohol; primary alcohol; sesquiterpenoid	antifeedant; antifungal agent; antineoplastic agent; fungal metabolite; mammalian metabolite; marine metabolite; plant metabolite
inuviscolide	[no description available]	low	0	gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone; tertiary alcohol	anti-inflammatory agent; plant metabolite
helioxanthin	[no description available]	low	0	benzodioxoles; furonaphthodioxole; lignan	anti-HBV agent; antineoplastic agent; plant metabolite
(2S)-5,7-dihydroxy-6,8-dimethylflavanone	[no description available]	low	0	dihydroxyflavanone	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
medioresinol	[no description available]	low	0	dimethoxybenzene; furofuran; lignan; polyphenol	plant metabolite
5-heptadecylresorcinol	[no description available]	low	0	5-alkylresorcinol	antineoplastic agent; plant metabolite
(+)-epicatechin	[no description available]	low	0	catechin; polyphenol	cyclooxygenase 1 inhibitor; plant metabolite
kobusin	[no description available]	low	0	benzodioxoles; dimethoxybenzene; furofuran; lignan	plant metabolite
nootkatol	[no description available]	low	0	6-isopropenyl-4,4a-dimethyl-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-ol	plant metabolite
ergolide	[no description available]	low	0	acetate ester; cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	anti-inflammatory agent; antineoplastic agent; metabolite; NF-kappaB inhibitor; plant metabolite
dihydroresveratrol	[no description available]	low	0	stilbenol	plant metabolite; xenobiotic metabolite
glycitin	[no description available]	low	0	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; methoxyisoflavone; monosaccharide derivative	plant metabolite
benzyl d-glucopyranoside	[no description available]	low	0	benzenes; beta-D-glucoside	plant metabolite
chrysosplenol c	[no description available]	low	0	trihydroxyflavone; trimethoxyflavone	antineoplastic agent; antiviral agent; plant metabolite
5-o-methyllicoricidin	[no description available]	low	0	aromatic ether; hydroxyisoflavans; methoxyisoflavan	antibacterial agent; plant metabolite
pronuciferine	[no description available]	low	0	aromatic ether; cyclic ketone; isoquinoline alkaloid; isoquinolines; organic heterotetracyclic compound	plant metabolite
santonin	[no description available]	low	0	botanical anti-fungal agent; santonin	plant metabolite
sandaracopimaric acid	[no description available]	low	0	monocarboxylic acid; pimarane diterpenoid; tricyclic diterpenoid	plant metabolite
erythritol	[no description available]	low	0	butane-1,2,3,4-tetrol	antioxidant; human metabolite; plant metabolite
stigmastanol	[no description available]	low	0	3-hydroxy steroid; phytosterols	anticholesteremic drug; plant metabolite
3-octanone	[no description available]	low	0	dialkyl ketone	antifeedant; biomarker; fungal metabolite; human urinary metabolite; insect attractant; plant metabolite; toxin
lanosterol	[no description available]	low	0	14alpha-methyl steroid; 3beta-sterol; tetracyclic triterpenoid	bacterial metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
noscapine	[no description available]	low	0	aromatic ether; benzylisoquinoline alkaloid; cyclic acetal; isobenzofuranone; organic heterobicyclic compound; organic heterotricyclic compound; tertiary amino compound	antineoplastic agent; antitussive; apoptosis inducer; plant metabolite
aromaticin	[no description available]	low	0	cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	anti-inflammatory agent; metabolite; plant metabolite
methyl 3,4-dihydroxybenzoate	[no description available]	low	0	catechols; methyl ester	antioxidant; neuroprotective agent; plant metabolite
2-hydroxy-1,4-benzoxazin-3-one	[no description available]	low	0	benzoxazine; lactam; lactol	allelochemical; plant metabolite
menthofuran	[no description available]	low	0	1-benzofurans; monoterpenoid	nematicide; plant metabolite
lariciresinol	[no description available]	low	0	aromatic ether; lignan; oxolanes; phenols; primary alcohol	antifungal agent; plant metabolite
medicarpin	[no description available]	low	0	medicarpin	plant metabolite
anthricin	[no description available]	low	0	furonaphthodioxole; gamma-lactone; lignan; methoxybenzenes	antineoplastic agent; apoptosis inducer; plant metabolite
indole-3-acetonitrile	[no description available]	low	0	indoles; nitrile	auxin; human xenobiotic metabolite; plant hormone; plant metabolite
taiwanin c	[no description available]	low	0	benzodioxoles; furonaphthodioxole; lignan	antineoplastic agent; plant metabolite; platelet aggregation inhibitor
sampangine	[no description available]	low	0	alkaloid; organic heterotetracyclic compound	antifungal agent; plant metabolite
isochamaejasmin	[no description available]	low	0	biflavonoid; hydroxyflavone	plant metabolite
norbelladine	[no description available]	low	0	catechols; phenethylamine alkaloid; polyphenol; secondary amino compound	plant metabolite
canavanine	[no description available]	low	0	amino acid zwitterion; non-proteinogenic L-alpha-amino acid	phytogenic insecticide; plant metabolite
raffinose	[no description available]	low	0	raffinose family oligosaccharide; trisaccharide	mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
5-hydroxytryptophan	[no description available]	low	0	5-hydroxytryptophan; amino acid zwitterion; hydroxy-L-tryptophan; non-proteinogenic L-alpha-amino acid	human metabolite; mouse metabolite; plant metabolite
theanine	[no description available]	low	0	amino acid zwitterion; N(5)-alkyl-L-glutamine	geroprotector; neuroprotective agent; plant metabolite
ouabain	[no description available]	low	0	11alpha-hydroxy steroid; 14beta-hydroxy steroid; 5beta-hydroxy steroid; alpha-L-rhamnoside; cardenolide glycoside; steroid hormone	anti-arrhythmia drug; cardiotonic drug; EC 2.3.3.1 [citrate (Si)-synthase] inhibitor; EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; ion transport inhibitor; plant metabolite
scopolin	[no description available]	low	0	beta-D-glucoside; coumarins; monosaccharide derivative	plant metabolite
stachyose	[no description available]	low	0	raffinose family oligosaccharide; tetrasaccharide	mouse metabolite; plant metabolite
isomaltulose	[no description available]	low	0	glycosylfructose	animal metabolite; plant metabolite; sweetening agent
discretamine	[no description available]	low	0	berberine alkaloid; organic heterotetracyclic compound	EC 5.99.1.2 (DNA topoisomerase) inhibitor; plant metabolite
mimosine	[no description available]	low	0	4-pyridones; amino acid zwitterion; non-proteinogenic L-alpha-amino acid	EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
pelargonidin	[no description available]	low	0	5-hydroxyanthocyanidin	plant metabolite
(+)-limonene	[no description available]	low	0	limonene	plant metabolite
hygrine	[no description available]	low	0	1-(1-methylpyrrolidin-2-yl)acetone; pyrrolidine alkaloid	plant metabolite
canaline	[no description available]	low	0	amino acid zwitterion; non-proteinogenic L-alpha-amino acid	antimetabolite; antineoplastic agent; phytogenic insecticide; plant metabolite
norpseudoephedrine	[no description available]	low	0	amphetamines; phenethylamine alkaloid	central nervous system stimulant; plant metabolite; psychotropic drug
sophoranone	[no description available]	low	0	4'-hydroxyflavanones; dihydroxyflavanone	plant metabolite
petunidin	[no description available]	low	0	5-hydroxyanthocyanidin	plant metabolite
helveticoside	[no description available]	low	0	14beta-hydroxy steroid; 5beta-hydroxy steroid; cardenolide glycoside; digitoxoside; monosaccharide derivative; steroid aldehyde; steroid lactone	antineoplastic agent; apoptosis inducer; plant metabolite
ginsenoside re	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; nephroprotective agent; neuroprotective agent; plant metabolite
ginsenoside rf	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; plant metabolite
3-o-(alpha-l-arabinopyranosyl)hederagenin	[no description available]	low	0	alpha-L-arabinopyranoside; hydroxy monocarboxylic acid; monosaccharide derivative; pentacyclic triterpenoid; triterpenoid saponin	plant metabolite
notoginsenoside r1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antioxidant; apoptosis inducer; neuroprotective agent; phytoestrogen; plant metabolite
2-(2-phenylethyl)chromone	[no description available]	low	0	benzenes; chromones	plant metabolite
ferruginol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; meroterpenoid; phenols	antibacterial agent; antineoplastic agent; plant metabolite; protective agent
stevioside	[no description available]	low	0	beta-D-glucoside; bridged compound; diterpene glycoside; ent-kaurane diterpenoid; tetracyclic diterpenoid	anti-inflammatory agent; antineoplastic agent; antioxidant; hypoglycemic agent; plant metabolite; sweetening agent
lenticin	[no description available]	low	0	amino-acid betaine; indole alkaloid; L-tryptophan derivative	fungal metabolite; plant metabolite; xenobiotic
absynthin	[no description available]	low	0	organic heteroheptacyclic compound; sesquiterpene lactone; triterpenoid	anti-inflammatory agent; plant metabolite
abyssinone i	[no description available]	low	0	monohydroxyflavanone; phenols	apoptosis inhibitor; plant metabolite
afzelechin	[no description available]	low	0	catechin; tetrahydroxyflavan	EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite
asebogenin	[no description available]	low	0	dihydrochalcones	plant metabolite
picrotin	[no description available]	low	0	diol; epoxide; gamma-lactone; organic heteropentacyclic compound; picrotoxane sesquiterpenoid; tertiary alcohol	plant metabolite
picrotoxinin	[no description available]	low	0	epoxide; gamma-lactone; organic heteropentacyclic compound; picrotoxane sesquiterpenoid; tertiary alcohol	GABA antagonist; plant metabolite; serotonergic antagonist
solavetivone	[no description available]	low	0	cyclic ketone; sesquiterpenoid; spiro compound	phytoalexin; plant metabolite
thujopsene	[no description available]	low	0	thujopsene	plant metabolite
agnuside	[no description available]	low	0	benzoate ester; beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monosaccharide derivative; phenols; terpene glycoside	anti-inflammatory agent; cyclooxygenase 2 inhibitor; plant metabolite; pro-angiogenic agent
dolichodial	[no description available]	low	0	dialdehyde; iridoid monoterpenoid; olefinic compound	animal metabolite; plant metabolite; volatile oil component
theasinensin a	[no description available]	low	0	biflavonoid; gallate ester; proanthocyanidin	anti-inflammatory agent; anticoronaviral agent; apoptosis inducer; EC 3.2.1.20 (alpha-glucosidase) inhibitor; hepatoprotective agent; hypoglycemic agent; melanin synthesis inhibitor; plant metabolite
5,6,7-trimethoxyflavone	[no description available]	low	0	trimethoxyflavone	anti-HSV-1 agent; plant metabolite
ammodendrine	[no description available]	low	0	acetamides; N-acylpiperidine; piperidine alkaloid	plant metabolite; teratogenic agent
carpaine	[no description available]	low	0	alkaloid; macrodiolide	cardiovascular drug; plant metabolite
myosmine	[no description available]	low	0	pyridine alkaloid; pyrroline	EC 1.14.14.14 (aromatase) inhibitor; mutagen; plant metabolite
dihydropinosylvin	[no description available]	low	0	diphenylethane; resorcinols	EC 1.14.18.1 (tyrosinase) inhibitor; plant metabolite
gingerol	[no description available]	low	0	beta-hydroxy ketone; guaiacols	antineoplastic agent; plant metabolite
mucronulatol	[no description available]	low	0	hydroxyisoflavans; methoxyisoflavan	antineoplastic agent; plant metabolite
ononin	[no description available]	low	0	4'-methoxyisoflavones; 7-hydroxyisoflavones 7-O-beta-D-glucoside; monosaccharide derivative	plant metabolite
yatein	[no description available]	low	0	benzodioxoles; butan-4-olide; lignan; methoxybenzenes	plant metabolite
solasodine	[no description available]	low	0	alkaloid antibiotic; azaspiro compound; hemiaminal ether; oxaspiro compound; sapogenin; steroid alkaloid	anticonvulsant; antifungal agent; antiinfective agent; antioxidant; antipyretic; antispermatogenic agent; apoptosis inducer; cardiotonic drug; central nervous system depressant; diuretic; immunomodulator; plant metabolite; teratogenic agent
1-alpha-terpineol	[no description available]	low	0	alpha-terpineol	plant metabolite
7-deoxyloganic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monosaccharide derivative; monoterpene glycoside	plant metabolite
epiafzelechin	[no description available]	low	0	catechin	plant metabolite
maleic acid	[no description available]	low	0	butenedioic acid	algal metabolite; mouse metabolite; plant metabolite
e-z cinnamic acid	[no description available]	low	0	cinnamic acid	plant metabolite
farnesol	[no description available]	low	0	farnesol	plant metabolite
retinol	[no description available]	low	0	retinol; vitamin A	human metabolite; mouse metabolite; plant metabolite
cocaine	[no description available]	low	0	benzoate ester; methyl ester; tertiary amino compound; tropane alkaloid	adrenergic uptake inhibitor; central nervous system stimulant; dopamine uptake inhibitor; environmental contaminant; local anaesthetic; mouse metabolite; plant metabolite; serotonin uptake inhibitor; sodium channel blocker; sympathomimetic agent; vasoconstrictor agent; xenobiotic
benzoylecgonine	[no description available]	low	0	benzoate ester; tropane alkaloid	epitope; human xenobiotic metabolite; marine xenobiotic metabolite; plant metabolite
zeatin	[no description available]	low	0	zeatin	plant metabolite
gamma-sitosterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; phytosterols	marine metabolite; plant metabolite
costatolide	[no description available]	low	0	cyclic ether; delta-lactone; organic heterotetracyclic compound; secondary alcohol	HIV-1 reverse transcriptase inhibitor; plant metabolite
euscaphic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid; triol	plant metabolite
cinnamtannin b-1	[no description available]	low	0	proanthocyanidin	cyclooxygenase 2 inhibitor; plant metabolite
meso-dihydroguaiaretic acid	[no description available]	low	0	guaiacols; lignan	plant metabolite
8-prenylnaringenin	[no description available]	low	0	(2S)-flavan-4-one; 4'-hydroxyflavanones; trihydroxyflavanone	plant metabolite; platelet aggregation inhibitor
gancaonin I	[no description available]	low	0	1-benzofurans; aromatic ether; resorcinols	antibacterial agent; plant metabolite
6,8-diprenylgenistein	[no description available]	low	0	7-hydroxyisoflavones	antibacterial agent; plant metabolite
glycyrin	[no description available]	low	0	aromatic ether; coumarins; hydroxyisoflavans	antibacterial agent; metabolite; plant metabolite
glyasperin D	[no description available]	low	0	aromatic ether; hydroxyisoflavans; methoxyisoflavan	plant metabolite
licoricidin	[no description available]	low	0	aromatic ether; hydroxyisoflavans; methoxyisoflavan	antibacterial agent; plant metabolite
pallidol	[no description available]	low	0	carbopolycyclic compound; polyphenol; stilbenoid	antifungal agent; antioxidant; plant metabolite
egonol	[no description available]	low	0	1-benzofurans; aromatic ether; benzodioxoles; primary alcohol	plant metabolite
23-hydroxytormentic acid	[no description available]	low	0	hydroxy monocarboxylic acid; pentacyclic triterpenoid; tetrol	anti-inflammatory agent; plant metabolite
riboflavin	[no description available]	low	0	flavin; vitamin B2	anti-inflammatory agent; antioxidant; cofactor; Escherichia coli metabolite; food colouring; fundamental metabolite; human urinary metabolite; mouse metabolite; photosensitizing agent; plant metabolite
licocoumarone	[no description available]	low	0	1-benzofurans; aromatic ether; resorcinols	antibacterial agent; apoptosis inducer; EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
likviriton	[no description available]	low	0	beta-D-glucoside; flavanone glycoside; monohydroxyflavanone; monosaccharide derivative	anti-inflammatory agent; anticoronaviral agent; plant metabolite
sodium benzoate	[no description available]	low	0	organic sodium salt	algal metabolite; antimicrobial food preservative; drug allergen; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; human xenobiotic metabolite; plant metabolite
3-mercaptohexanol	[no description available]	low	0	alkanethiol; primary alcohol	flavouring agent; plant metabolite; Saccharomyces cerevisiae metabolite
3'-methoxyflavone	[no description available]	low	0	3'-methoxyflavones	plant metabolite
piperlactam s	[no description available]	low	0	alkaloid; aromatic ether; gamma-lactam; organic heterotetracyclic compound; phenols	anti-inflammatory agent; antioxidant; plant metabolite
piperyline	[no description available]	low	0	benzodioxoles; N-acylpyrrolidine; pyrrolidine alkaloid; tertiary carboxamide	antifungal agent; apoptosis inducer; plant metabolite
crotonic acid	[no description available]	low	0	2-butenoic acid	plant metabolite
rhapontin	[no description available]	low	0	rhaponticin	angiogenesis inhibitor; anti-allergic agent; anti-inflammatory agent; antilipemic drug; antineoplastic agent; apoptosis inducer; EC 2.3.1.85 (fatty acid synthase) inhibitor; hypoglycemic agent; neuroprotective agent; plant metabolite
cinnamaldehyde	[no description available]	low	0	3-phenylprop-2-enal; cinnamaldehydes	antifungal agent; EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor; flavouring agent; hypoglycemic agent; plant metabolite; sensitiser; vasodilator agent
methyl cinnamate	[no description available]	low	0	methyl cinnamate	antibacterial agent; fungal metabolite; nematicide; plant metabolite
trans-4-coumaric acid	[no description available]	low	0	4-coumaric acid	food component; mouse metabolite; plant metabolite
2,4-hexadienal	[no description available]	low	0	hexadienal; polyunsaturated fatty aldehyde; volatile organic compound	flavouring agent; plant metabolite
geraniol	[no description available]	low	0	3,7-dimethylocta-2,6-dien-1-ol; monoterpenoid; primary alcohol	allergen; fragrance; plant metabolite; volatile oil component
epipinoresinol	[no description available]	low	0	pinoresinol	marine metabolite; plant metabolite
sinapinic acid	[no description available]	low	0	sinapic acid	MALDI matrix material; plant metabolite
piperine	[no description available]	low	0	benzodioxoles; N-acylpiperidine; piperidine alkaloid; tertiary carboxamide	food component; human blood serum metabolite; NF-kappaB inhibitor; plant metabolite
squalene	[no description available]	low	0	triterpene	human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
coumestan	[no description available]	low	0	coumestans; delta-lactone	phytoestrogen; plant metabolite
p-hydroxycinnamaldehyde	[no description available]	low	0	cinnamaldehydes	apoptosis inducer; EC 1.14.13.39 (nitric oxide synthase) inhibitor; plant metabolite
n-methylproline	[no description available]	low	0	L-alpha-amino acid zwitterion; L-proline derivative; tertiary amino compound	human metabolite; plant metabolite
vedelianin	[no description available]	low	0	cyclic ether; organic heterotricyclic compound; resorcinols; stilbenoid	antineoplastic agent; plant metabolite
pedilstatin	[no description available]	low	0	acetate ester; phorbol ester; primary allylic alcohol	plant metabolite
nerol	[no description available]	low	0	3,7-dimethylocta-2,6-dien-1-ol	fragrance; plant metabolite; volatile oil component
cannabidiol	[no description available]	low	0	olefinic compound; phytocannabinoid; resorcinols	antimicrobial agent; plant metabolite
amygdalin	[no description available]	low	0	amygdalin	antineoplastic agent; apoptosis inducer; plant metabolite
3,3',4,5'-tetrahydroxystilbene	[no description available]	low	0	catechols; polyphenol; resorcinols; stilbenol	antineoplastic agent; apoptosis inducer; geroprotector; hypoglycemic agent; plant metabolite; protein kinase inhibitor; tyrosine kinase inhibitor
dehydrovomifoliol	[no description available]	low	0	dehydrovomifoliol	plant metabolite
isoeugenol	[no description available]	low	0	isoeugenol	plant metabolite
cotinine	[no description available]	low	0	N-alkylpyrrolidine; pyridines; pyrrolidin-2-ones; pyrrolidine alkaloid	antidepressant; biomarker; human xenobiotic metabolite; plant metabolite
huperzine a	[no description available]	low	0	organic heterotricyclic compound; primary amino compound; pyridone; sesquiterpene alkaloid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; neuroprotective agent; nootropic agent; plant metabolite
nootkatone	[no description available]	low	0	carbobicyclic compound; enone; sesquiterpenoid	fragrance; insect repellent; plant metabolite
geranyl acetate	[no description available]	low	0	acetate ester; monoterpenoid	plant metabolite
coniferyl alcohol	[no description available]	low	0	guaiacols; phenylpropanoid	animal metabolite; monolignol; mouse metabolite; pheromone; plant metabolite; volatile oil component
geranylacetone	[no description available]	low	0	monoterpene ketone	flavouring agent; fragrance; plant metabolite; volatile oil component
aurapten	[no description available]	low	0	coumarins; monoterpenoid	antihypertensive agent; antineoplastic agent; antioxidant; apoptosis inducer; dopaminergic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; gamma-secretase modulator; gastrointestinal drug; hepatoprotective agent; matrix metalloproteinase inhibitor; neuroprotective agent; plant metabolite; PPARalpha agonist; vulnerary
chlorogenic acid	[no description available]	low	0	cinnamate ester; tannin	food component; plant metabolite
goitrin	[no description available]	low	0	5-ethenyl-1,3-oxazolidine-2-thione	antiviral agent; plant metabolite
manool	[no description available]	low	0	labdane diterpenoid; tertiary alcohol	antibacterial agent; antineoplastic agent; plant metabolite
2-oxindole-3-acetic acid	[no description available]	low	0	indole-3-acetic acids; monocarboxylic acid; oxindoles	plant metabolite
bigelovin	[no description available]	low	0	acetate ester; cyclic ketone; gamma-lactone; organic heterotricyclic compound; sesquiterpene lactone	antineoplastic agent; apoptosis inducer; immunomodulator; plant metabolite
cyclanoline	[no description available]	low	0	berberine alkaloid; quaternary ammonium ion	EC 3.1.1.7 (acetylcholinesterase) inhibitor; plant metabolite
ladanein	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	antiviral agent; plant metabolite; radical scavenger
t-muurolol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	bacterial metabolite; fungicide; marine metabolite; plant metabolite; volatile oil component
alpha-carotene	[no description available]	low	0	carotenoid beta-end derivative; cyclic carotene	plant metabolite; provitamin A
citramalate	[no description available]	low	0	dicarboxylic acid dianion	human metabolite; plant metabolite
fraxin	[no description available]	low	0	aromatic ether; beta-D-glucoside; hydroxycoumarin	anti-inflammatory agent; hepatoprotective agent; plant metabolite
decaprenoic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; methyl-branched fatty acid; monoterpenoid; polyunsaturated fatty acid	antifungal agent; EC 1.14.18.1 (tyrosinase) inhibitor; melanin synthesis inhibitor; pheromone; plant metabolite
gallocatechin-3-gallate	[no description available]	low	0	catechin; gallate ester; polyphenol	plant metabolite
coniferin	[no description available]	low	0	aromatic ether; cinnamyl alcohol beta-D-glucoside; monosaccharide derivative	plant metabolite
biochanin a	[no description available]	low	0	4'-methoxyisoflavones; 7-hydroxyisoflavones	antineoplastic agent; EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
formononetin	[no description available]	low	0	4'-methoxyisoflavones; 7-hydroxyisoflavones	phytoestrogen; plant metabolite
gibberellin a1	[no description available]	low	0	C19-gibberellin; gibberellin monocarboxylic acid; lactone	plant metabolite
leukotriene a4	[no description available]	low	0	epoxy fatty acid; leukotriene; long-chain fatty acid; oxylipin; polyunsaturated fatty acid	human metabolite; mouse metabolite; plant metabolite
sinapine	[no description available]	low	0	acylcholine	antioxidant; photosynthetic electron-transport chain inhibitor; plant metabolite
trans-phytol	[no description available]	low	0	diterpenoid; long-chain primary fatty alcohol	algal metabolite; plant metabolite; schistosomicide drug
vitexin	[no description available]	low	0	C-glycosyl compound; trihydroxyflavone	antineoplastic agent; EC 3.2.1.20 (alpha-glucosidase) inhibitor; plant metabolite; platelet aggregation inhibitor
luteolin	[no description available]	low	0	3'-hydroxyflavonoid; tetrahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist
scopoletin	[no description available]	low	0	hydroxycoumarin	plant growth regulator; plant metabolite
beta carotene	[no description available]	low	0	carotenoid beta-end derivative; cyclic carotene	antioxidant; biological pigment; cofactor; ferroptosis inhibitor; human metabolite; mouse metabolite; plant metabolite; provitamin A
leukotriene b4	[no description available]	low	0	dihydroxy monocarboxylic acid; hydroxy polyunsaturated fatty acid; leukotriene; long-chain fatty acid	human metabolite; mouse metabolite; plant metabolite; vasoconstrictor agent
coniferaldehyde	[no description available]	low	0	cinnamaldehydes; guaiacols; phenylpropanoid	antifungal agent; plant metabolite
gossypetin	[no description available]	low	0	7-hydroxyflavonol; hexahydroxyflavone	plant metabolite
ayanin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
apiin	[no description available]	low	0	beta-D-glucoside; dihydroxyflavone; glycosyloxyflavone	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
(all-e) phytoene	[no description available]	low	0	phytoene	plant metabolite
vitamin d 2	[no description available]	low	0	hydroxy seco-steroid; seco-ergostane; vitamin D	bone density conservation agent; nutraceutical; plant metabolite; rodenticide
stigmasterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; phytosterols; stigmastane sterol	plant metabolite
sinapaldehyde	[no description available]	low	0	cinnamaldehydes; dimethoxybenzene; phenols	antifungal agent; plant metabolite
quercetin 3-o-glucopyranoside	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antineoplastic agent; antioxidant; antipruritic drug; bone density conservation agent; geroprotector; histamine antagonist; osteogenesis regulator; plant metabolite
3-methylkaempferol	[no description available]	low	0	monomethoxyflavone; trihydroxyflavone	plant metabolite
kaempferol	[no description available]	low	0	7-hydroxyflavonol; flavonols; tetrahydroxyflavone	antibacterial agent; geroprotector; human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; plant metabolite
abscisic acid	[no description available]	low	0	2-cis-abscisic acid	plant hormone; plant metabolite
senecionine	[no description available]	low	0	lactone; pyrrolizidine alkaloid; tertiary alcohol	plant metabolite
gamma-linolenic acid	[no description available]	low	0	linolenic acid; omega-6 fatty acid	human metabolite; mouse metabolite; plant metabolite
petroselinic acid	[no description available]	low	0	octadec-6-enoic acid	plant metabolite
cyclobenzaprine	[no description available]	low	0	9,11,13-octadecatrienoic acid	antineoplastic agent; plant metabolite
jasmonic acid	[no description available]	low	0	oxo monocarboxylic acid	jasmonates; plant metabolite
2-hexenal, z-isomer	[no description available]	low	0	2-hexenal	antibacterial agent; flavouring agent; plant metabolite
aureusidin	[no description available]	low	0	hydroxyaurone	plant metabolite
butein	[no description available]	low	0	chalcones; polyphenol	antineoplastic agent; antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor; geroprotector; hypoglycemic agent; plant metabolite; radiosensitizing agent; tyrosine kinase inhibitor
antheraxanthin	[no description available]	low	0	epoxycarotenol	biological pigment; marine metabolite; plant metabolite
astaxanthine	[no description available]	low	0	carotenol; carotenone	animal metabolite; anticoagulant; antioxidant; food colouring; plant metabolite
capsanthin	[no description available]	low	0	carotenone	plant metabolite
gardenia yellow	[no description available]	low	0	diester; disaccharide derivative; diterpenoid	antioxidant; food colouring; histological dye; plant metabolite
cryptoxanthins	[no description available]	low	0	carotenol	antioxidant; biomarker; plant metabolite; provitamin A
lutein	[no description available]	low	0	carotenol	food colouring; plant metabolite
hispidol	[no description available]	low	0	hydroxyaurone	plant metabolite
isobutrin	[no description available]	low	0	beta-D-glucoside; chalcones; monosaccharide derivative; phenols	anti-inflammatory agent; hepatoprotective agent; plant metabolite
cassaine	[no description available]	low	0	enoate ester; organic hydroxy compound; tertiary amino compound; tricyclic diterpenoid	antihypertensive agent; cardiotonic drug; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; local anaesthetic; plant metabolite; poison
okanin	[no description available]	low	0	benzenetriol; chalcones	plant metabolite
cucurbitacin i	[no description available]	low	0	cucurbitacin; tertiary alpha-hydroxy ketone	antineoplastic agent; plant metabolite
brassicasterol	[no description available]	low	0	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols	algal metabolite; animal metabolite; biomarker; EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor; human metabolite; marine metabolite; plant metabolite; sterol biosynthesis inhibitor
harman	[no description available]	low	0	harmala alkaloid; indole alkaloid fundamental parent; indole alkaloid	anti-HIV agent; EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
esculetin	[no description available]	low	0	hydroxycoumarin	antioxidant; plant metabolite; ultraviolet filter
7-hydroxycoumarin	[no description available]	low	0	hydroxycoumarin	fluorescent probe; food component; plant metabolite
eupatolide	[no description available]	low	0	gamma-lactone; germacranolide; homoallylic alcohol; secondary alcohol	antineoplastic agent; plant metabolite
petasin	[no description available]	low	0	alicyclic ketone; enoate ester; enone; sesquiterpenoid	anti-allergic agent; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator; plant metabolite; vasodilator agent
oleuropein	[no description available]	low	0	beta-D-glucoside; catechols; diester; methyl ester; pyrans; secoiridoid glycoside	anti-inflammatory agent; antihypertensive agent; antineoplastic agent; antioxidant; apoptosis inducer; NF-kappaB inhibitor; nutraceutical; plant metabolite; radical scavenger
apigenin dimethylether	[no description available]	low	0	dimethoxyflavone; monohydroxyflavone	plant metabolite
axillarin	[no description available]	low	0	dimethoxyflavone; tetrahydroxyflavone	plant metabolite
azaleatin	[no description available]	low	0	7-hydroxyflavonol; monomethoxyflavone; tetrahydroxyflavone	plant metabolite
chrysin	[no description available]	low	0	7-hydroxyflavonol; dihydroxyflavone	anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite
chrysosplenetin b	[no description available]	low	0	dihydroxyflavone; tetramethoxyflavone	antiviral agent; plant metabolite
diosmetin	[no description available]	low	0	3'-hydroxyflavonoid; monomethoxyflavone; trihydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; bone density conservation agent; cardioprotective agent; plant metabolite; tropomyosin-related kinase B receptor agonist; vasodilator agent
fisetin	[no description available]	low	0	3'-hydroxyflavonoid; 7-hydroxyflavonol; tetrahydroxyflavone	anti-inflammatory agent; antioxidant; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; metabolite; plant metabolite
galangin	[no description available]	low	0	7-hydroxyflavonol; trihydroxyflavone	antimicrobial agent; EC 3.1.1.3 (triacylglycerol lipase) inhibitor; plant metabolite
gossypin	[no description available]	low	0	7-hydroxyflavonol; glycosyloxyflavone; monosaccharide derivative; pentahydroxyflavone	neuroprotective agent; plant metabolite
hispidulin	[no description available]	low	0	monomethoxyflavone; trihydroxyflavone	anti-inflammatory agent; anticonvulsant; antineoplastic agent; antioxidant; apoptosis inducer; plant metabolite
euxanthone	[no description available]	low	0	phenols; xanthones	metabolite; plant metabolite
gartanin	[no description available]	low	0	polyphenol; xanthones	antineoplastic agent; plant metabolite
gentiacaulein	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
gentisein	[no description available]	low	0	polyphenol; xanthones	plant metabolite
gentisin	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
isogentisin	[no description available]	low	0	aromatic ether; polyphenol; xanthones	EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite
mangiferin	[no description available]	low	0	C-glycosyl compound; xanthones	anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite
1,8-dihydroxy-3,7-dimethoxyxanthone	[no description available]	low	0	aromatic ether; polyphenol; xanthones	plant metabolite
norathyriol	[no description available]	low	0	polyphenol; xanthones	antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor; plant metabolite
1,2,8-trihydroxy-6-methoxyxanthone	[no description available]	low	0	aromatic ether; polyphenol; xanthones	antioxidant; plant metabolite
kuwanon g	[no description available]	low	0	resorcinols; tetrahydroxyflavone	anti-inflammatory agent; plant metabolite
kuwanon h	[no description available]	low	0	resorcinols; tetrahydroxyflavone	plant metabolite
morusin	[no description available]	low	0	extended flavonoid; trihydroxyflavone	antineoplastic agent; plant metabolite
myricetin	[no description available]	low	0	7-hydroxyflavonol; hexahydroxyflavone	antineoplastic agent; antioxidant; cyclooxygenase 1 inhibitor; food component; geroprotector; hypoglycemic agent; plant metabolite
myricitrin	[no description available]	low	0	alpha-L-rhamnoside; glycosyloxyflavone; monosaccharide derivative; pentahydroxyflavone	anti-allergic agent; EC 1.14.13.39 (nitric oxide synthase) inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; plant metabolite
pachypodol	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	antiemetic; plant metabolite
quercetagetin	[no description available]	low	0	flavonols; hexahydroxyflavone	antioxidant; antiviral agent; plant metabolite
robinetin	[no description available]	low	0	7-hydroxyflavonol; pentahydroxyflavone	plant metabolite
robinin	[no description available]	low	0	dihydroxyflavone; glycosyloxyflavone	plant metabolite
santin	[no description available]	low	0	dihydroxyflavone; trimethoxyflavone	plant metabolite
wogonin	[no description available]	low	0	dihydroxyflavone; monomethoxyflavone	angiogenesis inhibitor; antineoplastic agent; cyclooxygenase 2 inhibitor; plant metabolite
7-hydroxy-6,4'-dimethoxyisoflavone	[no description available]	low	0	4'-methoxyisoflavones; 7-hydroxyisoflavones	plant metabolite
coumestrol	[no description available]	low	0	coumestans; delta-lactone; polyphenol	anti-inflammatory agent; antioxidant; plant metabolite
daidzein	[no description available]	low	0	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite
pterostilbene	[no description available]	low	0	diether; methoxybenzenes; stilbenol	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; neuroprotective agent; neurotransmitter; plant metabolite; radical scavenger
genistein-8-c-glucoside	[no description available]	low	0	7-hydroxyisoflavones; C-glycosyl compound	plant metabolite
5-o-caffeoylshikimic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; carboxylic ester; catechols; cyclohexenecarboxylic acid	plant metabolite
cynarine	[no description available]	low	0	alkyl caffeate ester; quinic acid	plant metabolite
iridin	[no description available]	low	0	4'-methoxyisoflavones; 7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; monosaccharide derivative	plant metabolite
rosmarinic acid	[no description available]	low	0	rosmarinic acid	geroprotector; plant metabolite
orobol	[no description available]	low	0	7-hydroxyisoflavones	anti-inflammatory agent; fungal metabolite; plant metabolite; radical scavenger
psi-baptigenin	[no description available]	low	0	7-hydroxyisoflavones; benzodioxoles	antiprotozoal drug; plant metabolite
puerarin	[no description available]	low	0	C-glycosyl compound; hydroxyisoflavone	plant metabolite
tectoridin	[no description available]	low	0	7-hydroxyisoflavones 7-O-beta-D-glucoside; hydroxyisoflavone; methoxyisoflavone; monosaccharide derivative	plant metabolite
tectorigenin	[no description available]	low	0	7-hydroxyisoflavones; methoxyisoflavone	anti-inflammatory agent; plant metabolite
wighteone	[no description available]	low	0	7-hydroxyisoflavones	antifungal agent; plant metabolite
maytansine	[no description available]	low	0	alpha-amino acid ester; carbamate ester; epoxide; maytansinoid; organic heterotetracyclic compound; organochlorine compound	antimicrobial agent; antimitotic; antineoplastic agent; plant metabolite; tubulin modulator
savinin	[no description available]	low	0	benzodioxoles; gamma-lactone; lignan	anti-inflammatory agent; anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; plant metabolite; T-cell proliferation inhibitor
tectochrysin	[no description available]	low	0	monohydroxyflavone; monomethoxyflavone	antidiarrhoeal drug; antineoplastic agent; plant metabolite
2'-hydroxygenistein	[no description available]	low	0	hydroxyisoflavone	plant metabolite
astragalin	[no description available]	low	0	beta-D-glucoside; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone	plant metabolite; trypanocidal drug
cinnamyl acetate	[no description available]	low	0	acetate ester	plant metabolite
kaempferol-3-o-galactoside	[no description available]	low	0	beta-D-galactoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	antifungal agent; plant metabolite
vitexin rhamnoside	[no description available]	low	0	C-glycosyl compound; disaccharide derivative; trihydroxyflavone	plant metabolite
kaempferol 3-o-sophoroside	[no description available]	low	0	sophoroside; trihydroxyflavone	plant metabolite
quercetin-3-o-sophoroside	[no description available]	low	0	sophoroside; tetrahydroxyflavone	antioxidant; plant metabolite
ethyl linoleate	[no description available]	low	0	long-chain fatty acid ethyl ester	anti-inflammatory agent; plant metabolite
plaunotol	[no description available]	low	0	diterpenoid; primary alcohol	anti-ulcer drug; antibacterial agent; antineoplastic agent; apoptosis inducer; nephroprotective agent; plant metabolite; vulnerary
sofalcone	[no description available]	low	0	aromatic ether; chalcones; monocarboxylic acid	anti-ulcer drug; antibacterial agent; gastrointestinal drug; plant metabolite
xanthoxin	[no description available]	low	0	apo carotenoid sesquiterpenoid; enal	plant growth retardant; plant metabolite
tocotrienol, alpha	[no description available]	low	0	tocotrienol; vitamin E	ferroptosis inhibitor; human metabolite; neuroprotective agent; plant metabolite
tocotrienol, beta	[no description available]	low	0	tocotrienol; vitamin E	antineoplastic agent; apoptosis inducer; plant metabolite
gamma-tocotrienol	[no description available]	low	0	tocotrienol; vitamin E	antineoplastic agent; antioxidant; apoptosis inducer; hepatoprotective agent; plant metabolite; radiation protective agent
tocotrienol, delta	[no description available]	low	0	tocotrienol; vitamin E	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bone density conservation agent; NF-kappaB inhibitor; plant metabolite; radiation protective agent; Saccharomyces cerevisiae metabolite
4-hydroxychalcone	[no description available]	low	0	chalcones; phenols	antihypertensive agent; plant metabolite
9-hydroxy-10,12-octadecadienoic acid	[no description available]	low	0	HODE; octadecadienoic acid	human metabolite; metabolite; mouse metabolite; plant metabolite
2-heptenal	[no description available]	low	0	enal; medium-chain fatty aldehyde; monounsaturated fatty aldehyde	plant metabolite; uremic toxin
2-nonenal, (trans)-isomer	[no description available]	low	0	enal; medium-chain fatty aldehyde; monounsaturated fatty aldehyde	plant metabolite
oleylamide	[no description available]	low	0	primary fatty amide	human metabolite; plant metabolite
1-monooleoyl-rac-glycerol	[no description available]	low	0	1-acylglycerol 18:1; monooleoylglycerol	plant metabolite
monolinolein	[no description available]	low	0	1-acylglycerol 18:2; rac-1-monoacylglycerol	antiviral agent; human metabolite; plant metabolite
methyl linoleate	[no description available]	low	0	fatty acid methyl ester	plant metabolite
vitamin k 1	[no description available]	low	0	phylloquinones; vitamin K	cofactor; human metabolite; plant metabolite
morphine	[no description available]	low	0	morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound	anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic
delta(3)-hexadecenoic acid	[no description available]	low	0	hexadecenoic acid	plant metabolite
stearidonic acid	[no description available]	low	0	long-chain fatty acid; octadecatetraenoic acid; omega-3 fatty acid	Daphnia galeata metabolite; mouse metabolite; plant metabolite
juniperonic acid	[no description available]	low	0	icosatetraenoic acid	plant metabolite
rosmarinic acid	[no description available]	low	0	carboxylic ester; monocarboxylic acid; phenylpropanoid; polyphenol	antioxidant; EC 1.1.1.21 (aldehyde reductase) inhibitor; non-steroidal anti-inflammatory drug; peripheral nervous system drug; plant metabolite; serine proteinase inhibitor
cannabigerol	[no description available]	low	0	phytocannabinoid; resorcinols	anti-inflammatory agent; antibacterial agent; antioxidant; appetite enhancer; cannabinoid receptor agonist; neuroprotective agent; plant metabolite
centaureidin	[no description available]	low	0	trihydroxyflavone; trimethoxyflavone	antineoplastic agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; plant metabolite
cinnamyl alcohol	[no description available]	low	0	cinnamyl alcohol	plant metabolite
7-demethylsuberosin	[no description available]	low	0	hydroxycoumarin	plant metabolite
kaempferol 3-o-rhamnoside	[no description available]	low	0	glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	anti-inflammatory agent; antibacterial agent; plant metabolite
syringin	[no description available]	low	0	beta-D-glucoside; dimethoxybenzene; monosaccharide derivative; primary alcohol	hepatoprotective agent; plant metabolite
3,3'-di-o-methylquercetin	[no description available]	low	0	3'-methoxyflavones; dimethoxyflavone; trihydroxyflavone	antibacterial agent; antineoplastic agent; apoptosis inducer; plant metabolite
glycitein	[no description available]	low	0	7-hydroxyisoflavone; methoxyisoflavone	fungal metabolite; phytoestrogen; plant metabolite
glycycoumarin	[no description available]	low	0	aromatic ether; coumarins; resorcinols	antispasmodic drug; plant metabolite
quadrangularin a	[no description available]	low	0	indanes; polyphenol; stilbenoid	antioxidant; plant metabolite
isoginkgetin	[no description available]	low	0	aromatic ether; biflavonoid	antineoplastic agent; EC 3.4.24.35 (gelatinase B) inhibitor; plant metabolite
isomangiferin	[no description available]	low	0	C-glycosyl compound; polyphenol; xanthones	anti-HSV-1 agent; plant metabolite
isosalipurposide	[no description available]	low	0	beta-D-glucoside; chalcones; monosaccharide derivative; resorcinols	antioxidant; plant metabolite
kaempferol-3-o-rutinoside	[no description available]	low	0	disaccharide derivative; kaempferol O-glucoside; rutinoside; trihydroxyflavone	metabolite; plant metabolite; radical scavenger
luteolin 4'-o-glucoside	[no description available]	low	0	beta-D-glucoside; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	plant metabolite
methyl linolenate	[no description available]	low	0	fatty acid methyl ester	insect attractant; plant metabolite
3'-o-methylorobol	[no description available]	low	0	hydroxyisoflavone; methoxyisoflavone	plant metabolite
1,3,6-trihydroxy-2-methyl-9,10-anthraquinone	[no description available]	low	0	trihydroxyanthraquinone	plant metabolite
cudraflavone c	[no description available]	low	0	tetrahydroxyflavone	antibacterial agent; antineoplastic agent; plant metabolite
muromonab-cd3	[no description available]	low	0	extended flavonoid; pyranochromane; trihydroxyflavone	anti-inflammatory agent; plant metabolite
neoglycyrol	[no description available]	low	0	aromatic ether; coumestans; delta-lactone; polyphenol	antineoplastic agent; plant metabolite
beta-ocimene	[no description available]	low	0	beta-ocimene	plant metabolite
ombuine	[no description available]	low	0	dimethoxyflavone; flavonols; trihydroxyflavone	anti-inflammatory agent; plant metabolite
osthenol	[no description available]	low	0	hydroxycoumarin	antifungal agent; plant metabolite
5,7-dihydroxy-4',6-dimethoxyflavone	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	plant metabolite
tiliroside	[no description available]	low	0	cinnamate ester; glycosyloxyflavone; monosaccharide derivative; trihydroxyflavone	plant metabolite
spiraeoside	[no description available]	low	0	beta-D-glucoside; flavonols; monosaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antineoplastic agent; antioxidant; plant metabolite
rhamnazin	[no description available]	low	0	aromatic ether; dimethoxyflavone; phenols; trihydroxyflavone	antineoplastic agent; plant metabolite
kaempferol-7-methyl ether	[no description available]	low	0	flavonols; monomethoxyflavone; trihydroxyflavone	plant metabolite
oridonin	[no description available]	low	0	cyclic hemiketal; enone; ent-kaurane diterpenoid; organic heteropentacyclic compound; secondary alcohol	angiogenesis inhibitor; anti-asthmatic agent; antibacterial agent; antineoplastic agent; apoptosis inducer; plant metabolite
7,8-dimethylalloxazine	[no description available]	low	0	7,8-dimethylbenzo[g]pteridine-2,4-dione	plant metabolite
ergothioneine	[no description available]	low	0	1,3-dihydroimidazole-2-thiones; amino-acid betaine; L-histidine derivative; sulfur-containing amino acid	antioxidant; chelator; fungal metabolite; plant metabolite; xenobiotic metabolite
ermanin	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	anti-inflammatory agent; antimycobacterial drug; antineoplastic agent; apoptosis inducer; plant metabolite
5-hydroxy-3,3',4',7-tetramethoxyflavone	[no description available]	low	0	3'-methoxyflavones; monohydroxyflavone; tetramethoxyflavone	plant metabolite
methyl 2,5-dihydroxycinnamate	[no description available]	low	0	cinnamate ester; hydroquinones; methyl ester	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; geroprotector; human urinary metabolite; plant metabolite
methyl ferulate	[no description available]	low	0	cinnamate ester; guaiacols; methyl ester	plant metabolite
lichexanthone	[no description available]	low	0	aromatic ether; phenols; xanthones	plant metabolite
glyceryl behenate	[no description available]	low	0	1-monoglyceride; fatty acid ester	antineoplastic agent; plant metabolite
ethyl oleate	[no description available]	low	0	long-chain fatty acid ethyl ester	acaricide; plant metabolite
2-pentenal	[no description available]	low	0	2-pentenal	plant metabolite
erucyl amide	[no description available]	low	0	13-docosenamide	EC 3.1.1.7 (acetylcholinesterase) inhibitor; human metabolite; mammalian metabolite; plant metabolite; rat metabolite
beta-damascenone	[no description available]	low	0	apo carotenoid monoterpenoid; cyclic monoterpene ketone; enone	fragrance; plant metabolite; volatile oil component
piperic acid	[no description available]	low	0	alpha,beta-unsaturated monocarboxylic acid; benzodioxoles	plant metabolite
pipercallosidine	[no description available]	low	0	alkaloid; benzodioxoles; enamide; secondary carboxamide	apoptosis inducer; metabolite; plant metabolite
dehydrodiconiferyl alcohol	[no description available]	low	0	1-benzofurans; guaiacols; guaiacyl lignin; primary alcohol	anti-inflammatory agent; plant metabolite
noreugenin	[no description available]	low	0	chromones; resorcinols	plant metabolite
decussatin	[no description available]	low	0	aromatic ether; phenols; xanthones	plant metabolite
ecdysterone	[no description available]	low	0	14alpha-hydroxy steroid; 20-hydroxy steroid; 22-hydroxy steroid; 25-hydroxy steroid; 2beta-hydroxy steroid; 3beta-sterol; ecdysteroid; phytoecdysteroid	animal metabolite; plant metabolite
beta-aminopropionitrile fumarate (2:1)	[no description available]	low	0	fumarate salt	antineoplastic agent; antirheumatic drug; collagen cross-linking inhibitor; plant metabolite
gamma-mangostin	[no description available]	low	0	phenols; xanthones	antineoplastic agent; plant metabolite; protein kinase inhibitor
irigenin	[no description available]	low	0	4'-methoxyisoflavones; hydroxyisoflavone	plant metabolite
5,4'-dihydroxy-7,3'-dimethoxyflavone	[no description available]	low	0	dihydroxyflavone; dimethoxyflavone	anti-allergic agent; anti-inflammatory agent; antibacterial agent; antioxidant; melanin synthesis inhibitor; plant metabolite
1,7-dihydroxy-4-methoxyxanthone	[no description available]	low	0	aromatic ether; phenols; xanthones	metabolite; plant metabolite
tetrahydroxycurcumin	[no description available]	low	0	beta-diketone; catechols; diarylheptanoid; enone; polyphenol	anti-inflammatory agent; neuroprotective agent; plant metabolite
zerumbone	[no description available]	low	0	cyclic ketone; sesquiterpenoid	anti-inflammatory agent; glioma-associated oncogene inhibitor; plant metabolite
semilicoisoflavone b	[no description available]	low	0	7-hydroxyisoflavones	EC 1.1.1.21 (aldehyde reductase) inhibitor; plant metabolite
lespenefril	[no description available]	low	0	alpha-L-rhamnoside; dihydroxyflavone; glycosyloxyflavone; monosaccharide derivative; polyphenol	anti-inflammatory agent; antidepressant; antineoplastic agent; apoptosis inducer; bone density conservation agent; hypoglycemic agent; immunomodulator; plant metabolite
quercetin 3-sambubioside	[no description available]	low	0	disaccharide derivative; quercetin O-glucoside; tetrahydroxyflavone	antioxidant; plant metabolite
baohuoside i	[no description available]	low	0	glycosyloxyflavone	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; plant metabolite
avicularin	[no description available]	low	0	alpha-L-arabinofuranoside; monosaccharide derivative; quercetin O-glycoside; tetrahydroxyflavone	hepatoprotective agent; plant metabolite
ochnaflavone	[no description available]	low	0	aromatic ether; biflavonoid; hydroxyflavone	anti-inflammatory agent; antiatherogenic agent; antibacterial agent; EC 3.1.1.4 (phospholipase A2) inhibitor; leukotriene antagonist; plant metabolite
isowighteone	[no description available]	low	0	7-hydroxyisoflavones	plant metabolite
triolein	[no description available]	low	0	triglyceride	Caenorhabditis elegans metabolite; plant metabolite
resiniferatoxin	[no description available]	low	0	carboxylic ester; diterpenoid; enone; monomethoxybenzene; organic heteropentacyclic compound; ortho ester; phenols; tertiary alpha-hydroxy ketone	analgesic; neurotoxin; plant metabolite; TRPV1 agonist
4-hydroxycordoin	[no description available]	low	0	aromatic ether; chalcones; polyphenol	anti-inflammatory agent; antibacterial agent; plant metabolite
n-feruloylserotonin	[no description available]	low	0	aromatic ether; cinnamamides; hydroxyindoles; phenols; secondary carboxamide	plant metabolite
zosteric acid	[no description available]	low	0	aryl sulfate; cinnamic acids	antifouling biocide; plant metabolite
eupomatenoid 6	[no description available]	low	0	benzofurans; phenols	anti-inflammatory agent; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; NF-kappaB inhibitor; plant metabolite
amaranthin betacyanin	[no description available]	low	0	disaccharide derivative; indoles; olefinic compound; tetrahydropyridine	biological pigment; plant metabolite
mevalonolactone	[no description available]	low	0	4-hydroxy-4-methyloxan-2-one	fungal metabolite; plant metabolite
coronardine	[no description available]	low	0	alkaloid ester; methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound	antileishmanial agent; antineoplastic agent; apoptosis inducer; plant metabolite
columbianadin	[no description available]	low	0	alpha,beta-unsaturated carboxylic ester; furanocoumarin	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; hepatoprotective agent; plant metabolite; rat metabolite
salannin	[no description available]	low	0	acetate ester; furans; limonoid; methyl ester; organic heteropentacyclic compound	antifeedant; insect growth regulator; plant metabolite
thunberginol f	[no description available]	low	0	catechols; gamma-lactone; isobenzofuranone	metabolite; plant metabolite
9-hydroxy-10,12,15-octadecatrienoic acid	[no description available]	low	0	9-HOTrE	plant metabolite
valerenic acid	[no description available]	low	0	carbobicyclic compound; monocarboxylic acid; sesquiterpenoid	GABA modulator; plant metabolite; sedative; volatile oil component
zeatin riboside	[no description available]	low	0	9-ribosylzeatin; nucleoside analogue	cytokinin; plant metabolite
acuminatin	[no description available]	low	0	1-benzofurans; dimethoxybenzene; neolignan; olefinic compound; ring assembly	fungal metabolite; plant metabolite
cucurbitacin I 2-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; cucurbitacin; monosaccharide derivative; tertiary alpha-hydroxy ketone; triterpenoid saponin	plant metabolite
perflubron	[no description available]	low	0	2-acyl-4-prenylphloroglucinol; chalcones	plant metabolite
tuberonic acid	[no description available]	low	0	cyclopentanones; homoallylic alcohol; oxo monocarboxylic acid; primary alcohol	jasmonates; plant metabolite
salvianolic acid B	[no description available]	low	0	1-benzofurans; catechols; dicarboxylic acid; enoate ester; polyphenol	anti-inflammatory agent; antidepressant; antineoplastic agent; antioxidant; apoptosis inducer; autophagy inhibitor; cardioprotective agent; hepatoprotective agent; hypoglycemic agent; neuroprotective agent; osteogenesis regulator; plant metabolite
trilobatin	[no description available]	low	0	aryl beta-D-glucoside; dihydrochalcones; monosaccharide derivative	anti-inflammatory agent; antioxidant; plant metabolite; sweetening agent
2',4',6'-trihydroxychalcone	[no description available]	low	0	chalcones	antifungal agent; plant metabolite
beta-tocopherol	[no description available]	low	0	tocopherol; vitamin E	food component; plant metabolite
nyasol	[no description available]	low	0	1,3-bis(p-hydroxyphenyl)pentane-1,4-diene	plant metabolite
ginsenoside rb2	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antiviral agent; hypoglycemic agent; plant metabolite
yunaconitine	[no description available]	low	0	acetate ester; aromatic ether; benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound	antifeedant; human urinary metabolite; phytotoxin; plant metabolite; xenobiotic
3-tyrosine	[no description available]	low	0	hydroxyphenylalanine; L-alpha-amino acid zwitterion; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; phenols	plant metabolite
alpha-solanine	[no description available]	low	0	glycoalkaloid; organic heterohexacyclic compound; steroid saponin; trisaccharide derivative	antineoplastic agent; apoptosis inducer; phytotoxin; plant metabolite
3-O-feruloyl-D-quinic acid	[no description available]	low	0	enoate ester; quinic acid	plant metabolite
ginsenoside f1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; 6alpha-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	apoptosis inhibitor; plant metabolite
capsiate	[no description available]	low	0	carboxylic ester; monomethoxybenzene; phenols	angiogenesis inhibitor; anti-allergic agent; anti-inflammatory agent; antioxidant; capsaicin receptor agonist; hypoglycemic agent; plant metabolite
p-coumaric acid glucoside	[no description available]	low	0	4-O-beta-D-glucosyl-4-coumaric acid	plant metabolite
ginsenoside m1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	anti-allergic agent; anti-inflammatory agent; antineoplastic agent; hepatoprotective agent; plant metabolite
nicotianamine	[no description available]	low	0	amino acid zwitterion; nicotianamine	chelator; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; plant metabolite
6''-o-malonyldaidzin	[no description available]	low	0	glycosyloxyisoflavone; hydroxyisoflavone; malonate ester; monosaccharide derivative	plant metabolite
ginsenoside f2	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	antineoplastic agent; apoptosis inducer; plant metabolite
ginsenoside rg3	[no description available]	low	0	ginsenoside; glycoside; tetracyclic triterpenoid	angiogenesis modulating agent; antineoplastic agent; apoptosis inducer; plant metabolite
4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acid	[no description available]	low	0	11-oxo steroid; 3-oxo steroid; 7-oxo steroid; ergostanoid; monocarboxylic acid; steroid acid	anti-inflammatory agent; antineoplastic agent; plant metabolite
hetacillin	[no description available]	low	0	guaiacols; lignan; oxolanes; polyphenol; tetrol	plant metabolite
kaempferol 7-o-glucoside	[no description available]	low	0	beta-D-glucoside; flavonols; kaempferol O-glucoside; monosaccharide derivative; trihydroxyflavone	metabolite; plant metabolite; radical scavenger
3-epi-fagomine	[no description available]	low	0	amino monosaccharide; hydroxypiperidine; primary alcohol; secondary alcohol; secondary amino compound; triol	EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor; EC 3.2.1.23 (beta-galactosidase) inhibitor; plant metabolite
akuammicine	[no description available]	low	0	methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	plant metabolite
demethylzeylasteral	[no description available]	low	0	arenecarbaldehyde; benzenediols; carbopolycyclic compound; cyclic ketone; enone; oxo monocarboxylic acid	anti-inflammatory agent; EC 2.4.1.17 (glucuronosyltransferase) inhibitor; immunosuppressive agent; nephroprotective agent; plant metabolite
alpha-cadinol	[no description available]	low	0	cadinane sesquiterpenoid; carbobicyclic compound; octahydronaphthalenes; tertiary alcohol	fungicide; plant metabolite; volatile oil component
11-hydroxysugiol	[no description available]	low	0	abietane diterpenoid; carbotricyclic compound; catechols; cyclic terpene ketone; meroterpenoid	EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant metabolite
triptohypol C	[no description available]	low	0	benzenediols; monocarboxylic acid; pentacyclic triterpenoid	apoptosis inducer; plant metabolite
trilobacin	[no description available]	low	0	butenolide; polyketide; triol	antineoplastic agent; plant metabolite
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone	[no description available]	low	0	chalcones; monomethoxybenzene; resorcinols	EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; plant metabolite
1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one	[no description available]	low	0	diarylheptanoid; enone; phenols	plant metabolite
6-deacetylnimbin	[no description available]	low	0	cyclic terpene ketone; diester; enone; furans; limonoid; methyl ester; tetracyclic triterpenoid	antifeedant; insect growth regulator; plant metabolite
1,7-bis(4-hydroxyphenyl)hepta-4E-6E-dien-3-one	[no description available]	low	0	diarylheptanoid; enone; phenols	plant metabolite
2,3-dihydro-3beta-methoxy withaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; secondary alcohol; withanolide	metabolite; plant metabolite
azadirone	[no description available]	low	0	acetate ester; cyclic terpene ketone; furans; limonoid; tetracyclic triterpenoid	antineoplastic agent; antiplasmodial drug; plant metabolite
dihydroartemisinic acid	[no description available]	low	0	carbobicyclic compound; monocarboxylic acid; octahydronaphthalenes; sesquiterpenoid	plant metabolite
atractyligenine	[no description available]	low	0	carbotetracyclic compound; dihydroxy monocarboxylic acid; ent-kaurane diterpenoid; tetracyclic diterpenoid	plant metabolite
dihydrogenistin	[no description available]	low	0	beta-D-glucoside; hydroxyisoflavanone; monosaccharide derivative	plant metabolite
n-benzylhexadecanamide	[no description available]	low	0	macamide; secondary carboxamide	EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; neuroprotective agent; plant metabolite
triphosphate	[no description available]	low	0	aldehyde; indole alkaloid; organic heteropentacyclic compound	plant metabolite
aspalathin	[no description available]	low	0	C-glycosyl compound; catechols; dihydrochalcones; polyketide; polyphenol	antioxidant; EC 1.17.3.2 (xanthine oxidase) inhibitor; hypoglycemic agent; plant metabolite
glyceryl ferulate	[no description available]	low	0	1-monoglyceride; aromatic ether; enoate ester; phenols	antioxidant; plant metabolite; ultraviolet filter
obolactone	[no description available]	low	0	2-pyranones; 4-pyranones	antineoplastic agent; plant metabolite
quinine	[no description available]	low	0	Aspidosperma alkaloid; epoxide; methyl ester; monoterpenoid indole alkaloid; organic heterohexacyclic compound	plant metabolite
alpha-onocerin	[no description available]	low	0	diol; olefinic compound; secondary alcohol; triterpenoid	plant metabolite
kalopanax saponin b	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
ginsenoside rd	[no description available]	low	0	beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	anti-inflammatory drug; apoptosis inducer; immunosuppressive agent; neuroprotective agent; plant metabolite; vulnerary
(+)-dehydrodiconiferyl alcohol	[no description available]	low	0	dehydrodiconiferyl alcohol	antioxidant; plant metabolite
viridiflorol	[no description available]	low	0	carbotricyclic compound; sesquiterpenoid; tertiary alcohol	anti-inflammatory agent; antifeedant; antimycobacterial drug; plant metabolite; volatile oil component
morelloflavone	[no description available]	low	0	biflavonoid; hydroxyflavanone; hydroxyflavone	plant metabolite
2alpha,3beta-dihydroxy-20(29)-lupen-28-oic acid	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
azadiradione	[no description available]	low	0	acetate ester; cyclic terpene ketone; furans; limonoid; tetracyclic triterpenoid	anti-inflammatory agent; antimycobacterial drug; plant metabolite
(-)-pinoresinol	[no description available]	low	0	pinoresinol	plant metabolite
oplodiol	[no description available]	low	0	carbobicyclic compound; octahydronaphthalenes; secondary alcohol; sesquiterpenoid; tertiary alcohol	plant metabolite
roburic acid	[no description available]	low	0	monocarboxylic acid; olefinic compound; tetracyclic triterpenoid	plant metabolite
ginsenoside rc	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	hypoglycemic agent; plant metabolite
ginsenoside rh1	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; ginsenoside; tetracyclic triterpenoid	plant metabolite
ginsenoside rb3	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	antidepressant; antioxidant; cardioprotective agent; neuroprotective agent; NMDA receptor antagonist; plant metabolite
eriodictyol 7-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; flavanone glycoside; monosaccharide derivative; trihydroxyflavanone	plant metabolite; radical scavenger
5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one	[no description available]	low	0	alkaloid; chromones; hydroxypiperidine; resorcinols; tertiary amino compound	anti-inflammatory agent; anti-ulcer drug; anticholesteremic drug; antileishmanial agent; antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; fungal metabolite; plant metabolite
astragaloside IV	[no description available]	low	0	pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; antioxidant; EC 4.2.1.1 (carbonic anhydrase) inhibitor; neuroprotective agent; plant metabolite; pro-angiogenic agent
1-O-feruloyl-beta-D-glucose	[no description available]	low	0	aromatic ether; beta-D-glucoside; cinnamate ester; phenols	antioxidant; plant metabolite
astragaloside ii	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; oxolanes; pentacyclic triterpenoid; triterpenoid saponin	plant metabolite
ligstroside	[no description available]	low	0	beta-D-glucoside; diester; methyl ester; phenols; pyrans; secoiridoid glycoside	antineoplastic agent; plant metabolite
23-hydroxyursolic acid	[no description available]	low	0	dihydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
dihydroconiferyl alcohol glucoside	[no description available]	low	0	beta-D-glucoside; monomethoxybenzene; monosaccharide derivative; primary alcohol	plant metabolite
oroxylin a-7-o-glucuronide	[no description available]	low	0	beta-D-glucosiduronic acid; glycosyloxyflavone; monohydroxyflavone; monomethoxyflavone; monosaccharide derivative	plant metabolite
5-deoxystrigol	[no description available]	low	0	indenofuran; strigolactone	plant metabolite
2,3-dihydrowithaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; secondary alcohol; withanolide	plant metabolite
vibsanin b	[no description available]	low	0	cyclic terpene ketone; enone; tertiary alcohol; vibsane diterpenoid	plant growth retardant; plant metabolite
malonylgenistin	[no description available]	low	0	beta-D-glucoside; glycosyloxyisoflavone; hydroxyisoflavone; malonate ester; monosaccharide derivative	plant metabolite
adonixanthin	[no description available]	low	0	carotenone; cyclic ketone; secondary alcohol	algal metabolite; animal metabolite; antineoplastic agent; bacterial metabolite; marine metabolite; plant metabolite
niga-ichigoside f1	[no description available]	low	0	beta-D-glucoside; monosaccharide derivative; pentacyclic triterpenoid; tetrol; triterpenoid saponin	plant metabolite
cinnamtannin a2	[no description available]	low	0	proanthocyanidin	plant metabolite
benzoylaconine	[no description available]	low	0	benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol	phytotoxin; plant metabolite
miltiradiene	[no description available]	low	0	abietadiene; carbotricyclic compound	plant metabolite
tricin 4'-o-(threo-beta-guaiacylglyceryl) ether	[no description available]	low	0	dimethoxybenzene; flavonolignan; polyphenol; primary alcohol; secondary alcohol	plant metabolite
triptotriterpenic acid a	[no description available]	low	0	diol; hydroxy monocarboxylic acid; pentacyclic triterpenoid	plant metabolite
cycloeucalenone	[no description available]	low	0	3-oxo-5alpha-steroid; cyclic terpene ketone; pentacyclic triterpenoid	plant metabolite
deoxyaconitine	[no description available]	low	0	acetate ester; benzoate ester; bridged compound; diol; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary amino compound	plant metabolite
ginsenoside rg2	[no description available]	low	0	12beta-hydroxy steroid; 20-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	anticoagulant; cardioprotective agent; plant metabolite
cauloside D	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; triterpenoid saponin	anti-inflammatory agent; plant metabolite
oxypaeoniflora	[no description available]	low	0	4-hydroxybenzoate ester; beta-D-glucoside; bridged compound; cyclic acetal; lactol; monoterpene glycoside	plant metabolite
5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one	[no description available]	low	0	aromatic ether; homoisoflavonoid; polyphenol	angiogenesis modulating agent; plant metabolite
vindolinine	[no description available]	low	0	methyl ester; monoterpenoid indole alkaloid; organic heteropentacyclic compound; tertiary amino compound	plant metabolite
rubusoside	[no description available]	low	0	beta-D-glucoside; bridged compound; steviol glycoside; tetracyclic diterpenoid	plant metabolite; sweetening agent
madecassoside	[no description available]	low	0	carboxylic ester; pentacyclic triterpenoid; trisaccharide derivative; triterpenoid saponin	anti-inflammatory agent; antioxidant; antirheumatic drug; plant metabolite; vulnerary
benzoylmesaconine	[no description available]	low	0	benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol	analgesic; antiinfective agent; plant metabolite
albiflorin	[no description available]	low	0	benzoate ester; beta-D-glucoside; bridged compound; gamma-lactone; monoterpene glycoside; secondary alcohol	neuroprotective agent; plant metabolite
6-tuliposide b	[no description available]	low	0	6-O-acyl-D-glucose; enoate ester	antibacterial agent; antifungal agent; plant metabolite
quercetin 3-o-glucoside-7-o-rhamnoside	[no description available]	low	0	beta-D-glucoside; quercetin O-glucoside; trihydroxyflavone	plant metabolite; trypanocidal drug
10-nonacosanol	[no description available]	low	0	secondary fatty alcohol; ultra-long-chain fatty alcohol	plant metabolite
(E)-sinapaldehyde 4-O-beta-D-glucopyranoside	[no description available]	low	0	beta-D-glucoside; cinnamaldehydes; dimethoxybenzene; monosaccharide derivative	plant metabolite
1-(4-hydroxyphenyl)-7-phenyl-(6E)-hept-6-en-3-one	[no description available]	low	0	diarylheptanoid; ketone; phenols	plant metabolite
kurarinol	[no description available]	low	0	4'-hydroxyflavanones; monomethoxyflavanone; trihydroxyflavanone	anti-inflammatory agent; antioxidant; plant metabolite
2,3-dihydro-3beta-O-sulfate withaferin A	[no description available]	low	0	27-hydroxy steroid; 4-hydroxy steroid; delta-lactone; epoxy steroid; ergostanoid; primary alcohol; steroid sulfate; withanolide	antineoplastic agent; metabolite; plant metabolite
gypenoside XVII	[no description available]	low	0	12beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	plant metabolite
euonine	[no description available]	low	0	acetate ester; dihydroagarofuran sesquiterpenoid; macrolide; pyridine alkaloid; sesquiterpene alkaloid	immunosuppressive agent; insecticide; plant metabolite
picrinine	[no description available]	low	0	alkaloid ester; indole alkaloid; methyl ester; organic heteropentacyclic compound; polycyclic ether	analgesic; anti-asthmatic agent; anti-inflammatory agent; antitussive; plant metabolite
(20R)-ginsenoside Rg3	[no description available]	low	0	ginsenoside; glycoside; tetracyclic triterpenoid	antioxidant; plant metabolite
epoxyazadiradione	[no description available]	low	0	acetate ester; cyclic terpene ketone; epoxide; furans; limonoid; pentacyclic triterpenoid	anti-inflammatory agent; insecticide; plant metabolite
n-(2-(5-methoxy-2-oxo-2,3-dihydro-1h-indol-3-yl)ethyl)acetamide	[no description available]	low	0	acetamides; hydroxyindoles; tryptamines	antineoplastic agent; apoptosis inducer; plant metabolite
salicylates	[no description available]	low	0	monohydroxybenzoate	plant metabolite
orobanchol	[no description available]	low	0	indenofuran; secondary alcohol; strigolactone	plant metabolite
oleuropein aglycone	[no description available]	low	0	catechols; diester; lactol; methyl ester; pyrans; secoiridoid	anti-inflammatory agent; antioxidant; mTOR inhibitor; neuroprotective agent; plant metabolite; TRPA1 channel agonist
stemmadenine	[no description available]	low	0	Aspidosperma alkaloid; methyl ester; monoterpenoid indole alkaloid; organic heterotetracyclic compound; primary alcohol	plant metabolite
capilliposide b	[no description available]	low	0	alpha-L-arabinopyranoside; bridged compound; cyclic ether; diol; hexacyclic triterpenoid; hexanoate ester; lactol; secondary alcohol; tetrasaccharide derivative; triterpenoid saponin	antineoplastic agent; plant metabolite
paeoniflorigenone	[no description available]	low	0	alicyclic ketone; benzoate ester; bridged compound; cyclic acetal; lactol; monoterpenoid	neuromuscular agent; plant metabolite
maysin	[no description available]	low	0	disaccharide derivative; flavone C-glycoside; secondary alpha-hydroxy ketone; tetrahydroxyflavone	insecticide; neuroprotective agent; plant metabolite
cryptocaryol a	[no description available]	low	0	2-pyranones; pentol	plant metabolite
gypenoside LXXV	[no description available]	low	0	12beta-hydroxy steroid; 3beta-hydroxy-4,4-dimethylsteroid; 3beta-hydroxy steroid; beta-D-glucoside; disaccharide derivative; ginsenoside; tetracyclic triterpenoid	plant metabolite
chrysopine	[no description available]	low	0	amino acid opine; carboxamide; delta-lactone; secondary amino compound; spiroketal; triol	plant metabolite
ebc-46	[no description available]	low	0	diester; diterpenoid; organic heteropentacyclic compound; phorbol ester	antineoplastic agent; plant metabolite; protein kinase C agonist
wilforgine	[no description available]	low	0	acetate ester; dihydroagarofuran sesquiterpenoid; furans; macrocyclic lactone; organic heteropentacyclic compound; pyridine alkaloid	plant metabolite
dehydrotomatine	[no description available]	low	0	alkaloid antibiotic; glycoside; steroid alkaloid; tetrasaccharide derivative	antifungal agent; phytotoxin; plant metabolite
biliatresone	[no description available]	low	0	aromatic ether; aromatic ketone; benzodioxoles; enone; phenols	plant metabolite; toxin
cyclic gmp	[no description available]	low	0	3',5'-cyclic purine nucleotide; guanyl ribonucleotide	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
deoxyinosine	[no description available]	low	0	purine 2'-deoxyribonucleoside; purines 2'-deoxy-D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
deoxyguanosine triphosphate	[no description available]	low	0	deoxyguanosine phosphate; guanyl deoxyribonucleotide; purine 2'-deoxyribonucleoside 5'-triphosphate	Arabidopsis thaliana metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
guanosine diphosphate mannose	[no description available]	low	0	GDP-D-mannose	Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite
hydroxyzine	[no description available]	low	0	hydroxyether; monochlorobenzenes; N-alkylpiperazine	anticoronaviral agent; antipruritic drug; anxiolytic drug; dermatologic drug; H1-receptor antagonist
promethazine hydrochloride	[no description available]	low	0	hydrochloride	anti-allergic agent; anticoronaviral agent; antiemetic; antipruritic drug; geroprotector; H1-receptor antagonist; local anaesthetic; sedative
chlorpromazine hydrochloride	[no description available]	low	0	hydrochloride; phenothiazines	anticoronaviral agent; phenothiazine antipsychotic drug
chlorphenoxamine	[no description available]	low	0	diarylmethane	anticoronaviral agent
triparanol	[no description available]	low	0	stilbenoid	anticoronaviral agent
5-bromoisatin	[no description available]	low	0	indoles	anticoronaviral agent
5-Methoxyisatin	[no description available]	low	0	indoles	anticoronaviral agent
gemcitabine hydrochloride	[no description available]	low	0	hydrochloride; organofluorine compound	anticoronaviral agent; antimetabolite; antineoplastic agent; antiviral drug; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; immunosuppressive agent; radiosensitizing agent
amodiaquine hydrochloride	[no description available]	low	0	hydrochloride	anticoronaviral agent
siquil	[no description available]	low	0	hydrochloride	anticoronaviral agent
fluphenazine hydrochloride	[no description available]	low	0	phenothiazines	anticoronaviral agent
clomipramine hydrochloride	[no description available]	low	0	hydrochloride	anticoronaviral agent; antidepressant; serotonergic antagonist; serotonergic drug
loperamide hydrochloride	[no description available]	low	0	hydrochloride	anticoronaviral agent; antidiarrhoeal drug; mu-opioid receptor agonist
methotrimeprazine	[no description available]	low	0	phenothiazines; tertiary amine	anticoronaviral agent; cholinergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; non-narcotic analgesic; phenothiazine antipsychotic drug; serotonergic antagonist
5-Chloro-1H-indole-2,3-dione	[no description available]	low	0	indoles	anticoronaviral agent
5-iodoisatin	[no description available]	low	0	indoles	anticoronaviral agent
mizoribine	[no description available]	low	0	imidazoles	anticoronaviral agent
tanshinone	[no description available]	low	0	abietane diterpenoid	anticoronaviral agent
betulonic acid	[no description available]	low	0	triterpenoid	anticoronaviral agent
imatinib mesylate	[no description available]	low	0	methanesulfonate salt	anticoronaviral agent; antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
n(4)-hydroxycytidine	[no description available]	low	0	ketoxime; nucleoside analogue	anticoronaviral agent; antiviral agent; drug metabolite; human xenobiotic metabolite
sorafenib	[no description available]	low	0	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; phenylureas; pyridinecarboxamide	angiogenesis inhibitor; anticoronaviral agent; antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; ferroptosis inducer; tyrosine kinase inhibitor
5-Fluoroisatin	[no description available]	low	0	indoles	anticoronaviral agent
wortmannin	[no description available]	low	0	acetate ester; cyclic ketone; delta-lactone; organic heteropentacyclic compound	anticoronaviral agent; antineoplastic agent; autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector; Penicillium metabolite; radiosensitizing agent
1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide	[no description available]	low	0	indolecarboxamide	anticoronaviral agent
s 1033	[no description available]	low	0	(trifluoromethyl)benzenes; imidazoles; pyridines; pyrimidines; secondary amino compound; secondary carboxamide	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
(4-Methyl-2-oxochromen-7-yl) furan-2-carboxylate	[no description available]	low	0	coumarins	anticoronaviral agent
2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone	[no description available]	low	0	aromatic ketone	anticoronaviral agent
(4-Ethyl-2-oxochromen-7-yl) furan-2-carboxylate	[no description available]	low	0	coumarins	anticoronaviral agent
thiothixene	[no description available]	low	0	N-methylpiperazine	anticoronaviral agent
(4-Methoxyphenyl)-(2-methylsulfanyl-6,7-dihydro-[1,4]dioxino[2,3-f]benzimidazol-3-yl)methanone	[no description available]	low	0	benzodioxine	anticoronaviral agent
1-(N-[2-(Benzotriazol-1-yl)acetyl]-4-methoxyanilino)-N-cyclopentylcyclohexane-1-carboxamide	[no description available]	low	0	organonitrogen compound; organooxygen compound	anticoronaviral agent
(E)-4-Phenyl-2-(3-(thiophen-2-yl)acrylamido)thiophene-3-carboxylic acid	[no description available]	low	0	thiophenecarboxylic acid	anticoronaviral agent
CID 2131972	[no description available]	low	0	N-acylglycine	anticoronaviral agent
4-[4-(2,3,5,6-Tetramethylphenyl)sulfonylpiperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
4-[4-(2,3-Dimethylphenyl)piperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
4-[4-[3-(Trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one	[no description available]	low	0	quinolines	anticoronaviral agent
1-Benzyl-3-pyridin-3-yl-1H-pyrazole-4-carbaldehyde	[no description available]	low	0	pyrazolopyridine	anticoronaviral agent
2-Chloro-1-[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]ethan-1-one	[no description available]	low	0	pyrroles	anticoronaviral agent
N-[2-(2-Methoxyphenoxy)ethyl]-2-oxo-1H-quinoline-4-carboxamide	[no description available]	low	0	quinolines	anticoronaviral agent
tamoxifen citrate	[no description available]	low	0	citrate salt	angiogenesis inhibitor; anticoronaviral agent
6-methoxy-3-nitro-2-(phenylsulfonyl)pyridine	[no description available]	low	0	sulfonic acid derivative	anticoronaviral agent
5-(4-Chloro-benzenesulfonyl)-pyrimidine-2,4-diamine	[no description available]	low	0	sulfonic acid derivative	anticoronaviral agent
4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate	[no description available]	low	0	pyrrolidines	anticoronaviral agent
toremifene citrate	[no description available]	low	0	stilbenoid	anticoronaviral agent
CID 3191469	[no description available]	low	0	acetamides; anilide	anticoronaviral agent
CID 3192987	[no description available]	low	0	N-arylpiperazine	anticoronaviral agent
N-(4-Butan-2-ylphenyl)-N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]furan-2-carboxamide	[no description available]	low	0	aromatic amide; furans	anticoronaviral agent
N-[2-(Cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide	[no description available]	low	0	aromatic amide; furans	anticoronaviral agent
2-(N-[2-(Benzotriazol-1-yl)acetyl]-2,4,6-trimethylanilino)-N-tert-butyl-2-thiophen-3-ylacetamide	[no description available]	low	0	organonitrogen compound; organooxygen compound	anticoronaviral agent
CID 3198732	[no description available]	low	0	acetamides; anilide	anticoronaviral agent
CID 3206295	[no description available]	low	0	organonitrogen compound; organooxygen compound	anticoronaviral agent
1-(Chloroacetyl)-3-(1H-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-4-ol	[no description available]	low	0	indoles	anticoronaviral agent
8-(Trifluoromethyl)-9H-purin-6-amine	[no description available]	low	0	6-aminopurines	anticoronaviral agent
2-Chloro-1-[5-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one	[no description available]	low	0	dimethoxybenzene	anticoronaviral agent
1-(Chloroacetyl)-5-[4-(difluoromethoxy)-3-methoxyphenyl]-3-thien-2-yl-4,5-dihydro-1H-pyrazole	[no description available]	low	0	methoxybenzenes	anticoronaviral agent
2-Chloro-1-[3-(4-methylphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]ethanone	[no description available]	low	0	toluenes	anticoronaviral agent
5-Nitroisatin	[no description available]	low	0	indoles	anticoronaviral agent
N-Cyclopentyl-2-(N-methyl3-chlorobenzenesulfonamido)acetamide	[no description available]	low	0	sulfonamide	anticoronaviral agent
2-(Chloroacetyl)-N,2-diphenylhydrazinecarboxamide	[no description available]	low	0	ureas	anticoronaviral agent
N-(4-Nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide	[no description available]	low	0	aromatic amide	anticoronaviral agent
2-Chloro-1-[5-(furan-2-yl)-3-(5-methylfuran-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one	[no description available]	low	0	pyrazolidines	anticoronaviral agent
camostat mesylate	[no description available]	low	0	methanesulfonate salt	anti-inflammatory agent; anticoronaviral agent; antifibrinolytic drug; antihypertensive agent; antineoplastic agent; antiviral agent; serine protease inhibitor
cyclosporine	[no description available]	low	0	homodetic cyclic peptide	anti-asthmatic drug; anticoronaviral agent; antifungal agent; antirheumatic drug; carcinogenic agent; dermatologic drug; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; geroprotector; immunosuppressive agent; metabolite
sirolimus	[no description available]	low	0	antibiotic antifungal drug; cyclic acetal; cyclic ketone; ether; macrolide lactam; organic heterotricyclic compound; secondary alcohol	antibacterial drug; anticoronaviral agent; antineoplastic agent; bacterial metabolite; geroprotector; immunosuppressive agent; mTOR inhibitor
cinanserin	[no description available]	low	0	aryl sulfide; cinnamamides; secondary carboxamide; tertiary amino compound	anticoronaviral agent; antiviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide	[no description available]	low	0	benzotriazoles	anticoronaviral agent
N-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-alanyl-L-valyl-N-{(2S,3E)-5-(benzyloxy)-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pent-3-en-2-yl}-L-leucinamide	[no description available]	low	0	benzyl ester; isoxazoles; pyrrolidin-2-ones; tripeptide	anticoronaviral agent; antiviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
everolimus	[no description available]	low	0	cyclic acetal; cyclic ketone; ether; macrolide lactam; primary alcohol; secondary alcohol	anticoronaviral agent; antineoplastic agent; geroprotector; immunosuppressive agent; mTOR inhibitor
Ethyl (E,4S)-4-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-3-phenylpropanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate	[no description available]	low	0	dipeptide	anticoronaviral agent
5-Chloro-3-pyridinyl 2-furoate	[no description available]	low	0	carboxylic ester	anticoronaviral agent
plitidepsin	[no description available]	low	0	didemnin	anticoronaviral agent; antineoplastic agent; marine metabolite
sotrastaurin	[no description available]	low	0	indoles; maleimides; N-alkylpiperazine; N-arylpiperazine; quinazolines	anticoronaviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunosuppressive agent
alisporivir	[no description available]	low	0	homodetic cyclic peptide	anticoronaviral agent
PF-00835231	[no description available]	low	0	aromatic ether; indolecarboxamide; L-leucine derivative; primary alcohol; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; drug metabolite; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
Benzotriazol-1-yl 1H-indole-5-carboxylate	[no description available]	low	0	indolyl carboxylic acid	anticoronaviral agent
5-Bromopyridin-3-yl furan-2-carboxylate	[no description available]	low	0	carboxylic ester	anticoronaviral agent
5-Chloropyridin-3-yl 5-(4-chlorophenyl)furan-2-carboxylate	[no description available]	low	0	carboxylic ester	anticoronaviral agent
(5-Chloropyridin-3-yl) 1H-indole-5-carboxylate	[no description available]	low	0	indolyl carboxylic acid	anticoronaviral agent
5-Chloropyridin-3-yl 1H-indole-2-carboxylate	[no description available]	low	0	indolyl carboxylic acid	anticoronaviral agent
nutlin-3b	[no description available]	low	0	Nutlin; piperazinone	anticoronaviral agent
1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-5-methoxy-isatin	[no description available]	low	0	benzodioxine	anticoronaviral agent
1-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)-5-ethoxy-isatin	[no description available]	low	0	benzodioxine	anticoronaviral agent
brequinar sodium	[no description available]	low	0	organic sodium salt	anticoronaviral agent; antimetabolite; antineoplastic agent; antiviral agent; EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor; immunosuppressive agent; pyrimidine synthesis inhibitor
N-[5-Ethyl-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride	[no description available]	low	0	N-acyl-amino acid	anticoronaviral agent
N-[5-Bromo-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride	[no description available]	low	0	N-acyl-amino acid	anticoronaviral agent
N-[5-Fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride	[no description available]	low	0	N-acyl-amino acid	anticoronaviral agent
2-(3-Amino-3-oxopropyl)-3-(4-methylbenzoyl)-2H-indazole 1-oxide	[no description available]	low	0	benzoylpyrazole	anticoronaviral agent
3-(4-Amino-3,5-dichlorobenzoyl)-2-(3-amino-3-oxopropyl)-2H-indazole 1-oxide	[no description available]	low	0	benzoylpyrazole	anticoronaviral agent
2-(3-Amino-3-oxopropyl)-3-(4-chlorobenzoyl)-2H-indazole 1-oxide	[no description available]	low	0	benzoylpyrazole	anticoronaviral agent
(5-Chloropyridin-3-yl) 1H-indole-4-carboxylate	[no description available]	low	0	indolyl carboxylic acid	anticoronaviral agent
gsk 2126458	[no description available]	low	0	aromatic ether; difluorobenzene; pyridazines; pyridines; quinolines; sulfonamide	anticoronaviral agent; antineoplastic agent; autophagy inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor; radiosensitizing agent
dabrafenib	[no description available]	low	0	1,3-thiazoles; aminopyrimidine; organofluorine compound; sulfonamide	anticoronaviral agent; antineoplastic agent; B-Raf inhibitor
GS-441524	[no description available]	low	0	aromatic amine; C-nucleoside; nitrile; pyrrolotriazine	anticoronaviral agent; antiviral agent; drug metabolite
Benzyl N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]-1-(1,3-thiazol-2-yl)propan-2-yl]amino]pentan-2-yl]amino]-1-oxobutan-2-yl]carbamate	[no description available]	low	0	dipeptide	anticoronaviral agent
GS-443902	[no description available]	low	0	aromatic amine; C-nucleoside; nitrile; organic triphosphate; pyrrolotriazine	anticoronaviral agent; antiviral drug; drug metabolite
N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide	[no description available]	low	0	aldehyde; indolecarboxamide; oligopeptide; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
molnupiravir	[no description available]	low	0	isopropyl ester; ketoxime; nucleoside analogue	anticoronaviral agent; antiviral drug; prodrug
3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide	[no description available]	low	0	aldehyde; indolecarboxamide; monofluorobenzenes; oligopeptide; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
PF-07304814	[no description available]	low	0	aromatic ether; indolecarboxamide; L-leucine derivative; phosphate monoester; pyrrolidin-2-ones; secondary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; prodrug
nirmatrelvir	[no description available]	low	0	azabicyclohexane; nitrile; organofluorine compound; pyrrolidin-2-ones; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide	anticoronaviral agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
castanospermine	[no description available]	low	0	indolizidine alkaloid	anti-HIV-1 agent; anti-inflammatory agent; EC 3.2.1.* (glycosidase) inhibitor; metabolite

Article	Year
Protective effects and mechanisms of lycorine against adriamycin-induced cardiotoxicity. Phytomedicine : international journal of phytotherapy and phytopharmacology, Jul-20, Volume: 102	2022
Cytotoxicity studies of lycorine alkaloids of the Amaryllidaceae. Natural product communications, Volume: 9, Issue: 8	2014
Lycorine hydrochloride selectively inhibits human ovarian cancer cell proliferation and tumor neovascularization with very low toxicity. Toxicology letters, Apr-12, Volume: 218, Issue: 2	2013
Protective effects of lycorine against carbon tetrachloride induced hepatotoxicity in Swiss albino mice. Fundamental & clinical pharmacology, Volume: 26, Issue: 3	2012
Suppressive activity of lycoricidinol (narciclasine) against cytotoxicity of neutrophil-derived calprotectin, and its suppressive effect on rat adjuvant arthritis model. Biological & pharmaceutical bulletin, Volume: 22, Issue: 7	1999
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

lycorine

Description

Cross-References

Synonyms (79)

Research Excerpts

Overview

Effects

Actions

Treatment

Roles (4)

Drug Classes (1)

Pathways (1)

Protein Targets (6)

Potency Measurements

Inhibition Measurements

Biological Processes (14)

Molecular Functions (10)

Ceullar Components (13)

Bioassays (210)

Research

Studies (229)

Study Types

Research Highlights

Safety/Toxicity (5)

Pharmacokinetics (2)

Bioavailability (2)

Dosage (2)

Natural Sources (2)

Condition	Relationship Strength	Studies
2019 Novel Coronavirus Disease	low	3
2019 Novel Coronavirus Infection	low	3
2019-nCoV Disease	low	3
2019-nCoV Infection	low	3
Abdominal Pain	low	1
Ache	low	1
Acute Liver Injury, Drug-Induced	low	2
Acute Myelogenous Leukemia	low	1
Acute Myeloid Leukemia	low	1
Acute Myeloid Leukemia with Maturation	low	1
Acute Myeloid Leukemia without Maturation	low	1
Acute Promyelocytic Leukemia	low	2
Adenocarcinoma	low	1
Adenocarcinoma Of Kidney	low	2
Adenocarcinoma, Basal Cell	low	1
Adenocarcinoma, Granular Cell	low	1
Adenocarcinoma, Oxyphilic	low	1
Adenocarcinoma, Renal	low	2
Adenocarcinoma, Renal Cell	low	2
Adenocarcinoma, Tubular	low	1
Adenoma, Malignant	low	1
Adjuvant Arthritis	low	1
Age-Related Osteoporosis	low	1
Alveolitis, Fibrosing	low	1
AML M3	low	2
Anasarca	low	1
Angiogenesis, Pathologic	low	3
Angiogenesis, Pathological	low	3
ANLL	low	1
Arthritis, Adjuvant	low	1
Arthritis, Adjuvant-Induced	low	1
Arthritis, Collagen-Induced	low	1
Arthritis, Degenerative	low	1
Arthritis, Experimental	low	1
Arthroses	low	1
Arthrosis	low	1
Astrocytoma, Grade IV	low	1
Asymmetric Diabetic Proximal Motor Neuropathy	low	1
B-Cell Chronic Lymphocytic Leukemia	low	1
B-Cell Leukemia, Chronic	low	1
B-Cell Malignancy, Low-Grade	low	1
B-Lymphocytic Leukemia, Chronic	low	1
Benign Neoplasms	low	6
Bladder Cancer	low	1
Bladder Neoplasms	low	1
Bladder Tumors	low	1
Blood Poisoning	low	1
Blood Pressure, High	low	1
Bloodstream Infection	low	1
Body Weight	low	1
Bone Loss, Age-Related	low	1
Bone Loss, Osteoclastic	low	1
Bone Resorption	low	1
Breast Cancer	low	4
Breast Carcinoma	low	4
Breast Neoplasms	low	4
Breast Tumors	low	4
Cancer	low	6
Cancer of Bladder	low	1
Cancer of Breast	low	4
Cancer of Cervix	low	2
Cancer of Colon	low	2
Cancer of Liver	low	2
Cancer of Lung	low	5
Cancer of Ovary	low	1
Cancer of Pancreas	low	4
Cancer of Prostate	low	2
Cancer of Skin	low	3
Cancer of Stomach	low	2
Cancer of the Bladder	low	1
Cancer of the Breast	low	4
Cancer of the Cervix	low	2
Cancer of the Colon	low	2
Cancer of the Liver	low	2
Cancer of the Lung	low	5
Cancer of the Ovary	low	1
Cancer of the Pancreas	low	4
Cancer of the Prostate	low	2
Cancer of the Skin	low	3
Cancer of the Stomach	low	2
Cancer of the Uterine Cervix	low	2
Cancer, Hepatocellular	low	2
Carbon Tetrachloride Poisoning	low	1
Carcinogenesis	low	1
Carcinoma	low	1
Carcinoma, Anaplastic	low	1
Carcinoma, Cribriform	low	1
Carcinoma, Epidermoid	low	1
Carcinoma, Granular Cell	low	1
Carcinoma, Hepatocellular	low	1
Carcinoma, Hypernephroid	low	2
Carcinoma, Non-Small Cell Lung	low	3
Carcinoma, Non-Small-Cell Lung	low	3
Carcinoma, Planocellular	low	1
Carcinoma, Renal Cell	low	2
Carcinoma, Small Cell Lung	low	1
Carcinoma, Spindle-Cell	low	1
Carcinoma, Squamous	low	1
Carcinoma, Squamous Cell	low	1
Carcinoma, Tubular	low	1
Carcinoma, Undifferentiated	low	1
Carcinomatosis	low	1
Cardiac Diseases	low	1
Cardiac Disorders	low	1
Cardiac Remodeling, Ventricular	low	1
Cardiac Rupture, Traumatic	low	1
Cardiac Toxicity	low	1
Cardiomyopathies	low	1
Cardiomyopathies, Primary	low	1
Cardiomyopathies, Secondary	low	1
Cardiotoxicity	low	1
Cardiovascular Stroke	low	1
CCl4 Poisoning	low	1
Cell Transformation, Neoplastic	low	2
Cervical Cancer	low	2
Cervical Neoplasms	low	2
Cervix Cancer	low	2
Cervix Neoplasms	low	2
Chemical and Drug Induced Liver Injury	low	2
Chemically-Induced Liver Toxicity	low	2
Chromophil Renal Cell Carcinoma	low	2
Chromophobe Renal Cell Carcinoma	low	2
Chronic Lymphocytic Leukemia	low	1
Cirrhosis	low	2
Clear Cell Renal Carcinoma	low	2
Clear Cell Renal Cell Carcinoma	low	2
Colicky Pain	low	1
Collagen Arthritis	low	1
Collecting Duct Carcinoma	low	2
Collecting Duct Carcinoma (Kidney)	low	2
Collecting Duct Carcinoma of the Kidney	low	2
Colon Cancer	low	2
Colon Neoplasms	low	2
Colonic Cancer	low	2
Colonic Neoplasms	low	2
Colorectal Cancer	low	2
Colorectal Carcinoma	low	2
Colorectal Neoplasms	low	2
Colorectal Tumors	low	2
Congenital Zika Syndrome	low	1
Congenital Zika Virus Infection	low	1
Coronavirus Disease 2019	low	3
Coronavirus Disease-19	low	3
Coronavirus Infections	low	1
COVID-19	low	3
COVID-19 Pandemic	low	3
COVID-19 Pandemics	low	3
COVID-19 Virus Disease	low	3
COVID-19 Virus Infection	low	3
COVID19	low	3
Degenerative Disc Disease	low	1
Degenerative Intervertebral Discs	low	1
Degenerative Intervertebral Disks	low	1
Diabetic Amyotrophy	low	1
Diabetic Asymmetric Polyneuropathy	low	1
Diabetic Autonomic Neuropathy	low	1
Diabetic Mononeuropathy	low	1
Diabetic Mononeuropathy Simplex	low	1
Diabetic Neuralgia	low	1
Diabetic Neuropathies	low	1
Diabetic Neuropathy, Painful	low	1
Diabetic Polyneuropathy	low	1
Diffuse Well-Differentiated Lymphocytic Lymphoma	low	1
Disc Degeneration	low	1
Disc Degradation	low	1
Disease Models, Animal	low	8
Disease Resistance	low	1
Disk Degeneration	low	1
Disk Degradation	low	1
Disrupted In B-Cell Malignancy	low	1
Dropsy	low	1
Drug-Induced Acute Liver Injury	low	2
Drug-Induced Liver Disease	low	2
Drug-Induced Liver Injury	low	2
Edema	low	1
Emesis	low	3
Encephalitis, Japanese	low	1
Encephalitis, Japanese B	low	1
Encephalitis, Polio	low	1
Endotoxin Shock	low	1
Enterovirus Infections	low	2
Epidemic Acute Poliomyelitis	low	1
Epithelial Neoplasms, Malignant	low	1
Epithelial Tumors, Malignant	low	1
Epithelioma	low	1
Experimental Mammary Neoplasms	low	1
Experimental Neoplasms	low	1
Fever, Zika	low	1
Fibroses, Pulmonary	low	1
Fibrosis	low	2
Fibrosis, Pulmonary	low	1
Fish Diseases	low	1
Flavivirus Infections	low	1
Flavobacteriaceae Infections	low	1
Food Poisoning	low	1
Food-borne Disease	low	1
Food-borne Diseases	low	1
Food-borne Illness	low	1
Food-borne Illnesses	low	1
Foodborne Disease	low	1
Foodborne Diseases	low	1
Foodborne Illness	low	1
Foodborne Illnesses	low	1
Gastric Cancer	low	2
Gastric Cancer, Familial Diffuse	low	2
Gastric Neoplasms	low	2
Giant Cell Glioblastoma	low	1
Glial Cell Tumors	low	1
Glioblastoma	low	1
Glioblastoma Multiforme	low	1
Glioma	low	1
Grawitz Tumor	low	2
Hand Foot and Mouth Disease	low	1
Hand, Foot and Mouth Disease	low	1
Hand, Foot, and Mouth Disease	low	1
Hand, Foot, Mouth Disease	low	1
Heart Attack	low	1
Heart Diseases	low	1
Heart Disorders	low	1
Heart Injuries	low	1
Heart Rupture, Traumatic	low	1
Hepatic Cancer	low	2
Hepatic Neoplasms	low	2
Hepatitis C	low	1
Hepatitis, Drug-Induced	low	2
Hepatitis, Toxic	low	2
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted	low	1
Hepatoblastoma	low	1
Hepatocellular Cancer	low	2
Hepatocellular Carcinoma	low	1
Hepatoma	low	1
Human Mammary Carcinoma	low	4
Hydrops	low	1
Hypernephroma	low	2
Hypertension	low	1
Idiopathic Diffuse Interstitial Pulmonary Fibrosis	low	1
Idiopathic Parkinson Disease	low	1
Idiopathic Parkinson's Disease	low	1
Infantile Paralysis	low	1
Infections, Coronavirus	low	1
Infections, Enterovirus	low	2
Infections, Flavivirus	low	1
Infections, Plasmodium	low	2
Infections, RNA Virus	low	1
Infections, Trichomonas	low	1
Inflammation	low	1
Injuries, Heart	low	1
Innate Inflammatory Response	low	1
Intervertebral Disc Degeneration	low	1
Intervertebral Disk Degeneration	low	1
Invasiveness, Neoplasm	low	2
Japanese B Encephalitis	low	1
Japanese B Viral Encephalitis	low	1
Japanese Encephalitis	low	1
Kahler Disease	low	5
Left Ventricle Remodeling	low	1
Left Ventricular Remodeling	low	1
Leucocythaemia	low	1
Leucocythemia	low	1
Leukemia	low	1
Leukemia L5178	low	1
Leukemia P388	low	1
Leukemia, Acute Myelogenous	low	1
Leukemia, Acute Myeloid	low	1
Leukemia, Acute Promyelocytic	low	2
Leukemia, B Cell, Chronic	low	1
Leukemia, B-Cell, Chronic	low	1
Leukemia, Chronic Lymphatic	low	1
Leukemia, Chronic Lymphocytic	low	1
Leukemia, Chronic Lymphocytic, B-Cell	low	1
Leukemia, Lymphoblastic, Chronic	low	1
Leukemia, Lymphocytic, Chronic	low	1
Leukemia, Lymphocytic, Chronic, B Cell	low	1
Leukemia, Lymphocytic, Chronic, B-Cell	low	1
Leukemia, Myeloblastic, Acute	low	1
Leukemia, Myelocytic, Acute	low	1
Leukemia, Myelogenous, Acute	low	1
Leukemia, Myeloid, Acute	low	1
Leukemia, Myeloid, Acute, M1	low	1
Leukemia, Myeloid, Acute, M2	low	1
Leukemia, Myeloid, Acute, M3	low	2
Leukemia, Nonlymphoblastic, Acute	low	1
Leukemia, Nonlymphocytic, Acute	low	1
Leukemia, Progranulocytic	low	2
Leukemia, Promyelocytic, Acute	low	2
Leukemic Infiltration	low	1
Lewy Body Parkinson Disease	low	1
Lewy Body Parkinson's Disease	low	1
Liver Cancer	low	2
Liver Cancer, Adult	low	1
Liver Cell Carcinoma	low	1
Liver Cell Carcinoma, Adult	low	1
Liver Injury, Drug-Induced	low	2
Liver Injury, Drug-Induced, Acute	low	2
Liver Neoplasms	low	2
Lung Cancer	low	5
Lung Neoplasms	low	5
Lymphoblastic Leukemia, Chronic	low	1
Lymphocytic Leukemia, Chronic	low	1
Lymphocytic Leukemia, Chronic, B Cell	low	1
Lymphocytic Leukemia, Chronic, B-Cell	low	1
Lymphocytic Lymphoma	low	1
Lymphocytic Lymphoma, Diffuse, Well Differentiated	low	1
Lymphocytic Lymphoma, Diffuse, Well-Differentiated	low	1
Lymphocytic Lymphoma, Well Differentiated	low	1
Lymphocytic Lymphoma, Well-Differentiated	low	1
Lymphoma L5178	low	1
Lymphoma, Lymphocytic	low	1
Lymphoma, Lymphocytic, Diffuse, Well Differentiated	low	1
Lymphoma, Lymphocytic, Diffuse, Well-Differentiated	low	1
Lymphoma, Lymphocytic, Well Differentiated	low	1
Lymphoma, Lymphocytic, Well-Differentiated	low	1
Lymphoma, Lymphoplasmacytoid, CLL	low	1
Lymphoma, Small Lymphocytic	low	1
Lymphoma, Small Lymphocytic, Plasmacytoid	low	1
Lymphoma, Small-Cell	low	1
Lymphoplasmacytoid Lymphoma, CLL	low	1
M3 ANLL	low	2
Malaria	low	2
Malignancy	low	6
Malignant Epithelial Neoplasms	low	1
Malignant Glioma	low	1
Malignant Melanoma	low	4
Malignant Neoplasm of Breast	low	4
Malignant Neoplasms	low	6
Malignant Tumor of Breast	low	4
Malignant Tumor of Urinary Bladder	low	1
Mammary Cancer	low	4
Mammary Carcinoma, Human	low	4
Mammary Neoplasm, Human	low	4
Mammary Neoplasms, Experimental	low	1
Mammary Neoplasms, Human	low	4
Marsh Fever	low	2
Melanoma	low	4
MERS (Middle East Respiratory Syndrome)	low	1
Metastase	low	7
Metastases, Neoplasm	low	7
Metastasis	low	7
Metastasis, Neoplasm	low	7
Middle East Respiratory Syndrome	low	1
Mixed Glioma	low	1
Mononeuropathy, Diabetic	low	1
Multiple Myeloma	low	5
Myeloblastic Leukemia, Acute	low	1
Myelocytic Leukemia, Acute	low	1
Myelogenous Leukemia, Acute	low	1
Myeloid Leukemia, Acute	low	1
Myeloid Leukemia, Acute, M1	low	1
Myeloid Leukemia, Acute, M2	low	1
Myeloid Leukemia, Acute, M3	low	2
Myeloma-Multiple	low	5
Myeloma, Multiple	low	5
Myeloma, Plasma-Cell	low	5
Myelomatosis	low	5
Myocardial Diseases	low	1
Myocardial Diseases, Primary	low	1
Myocardial Diseases, Secondary	low	1
Myocardial Infarct	low	1
Myocardial Infarction	low	1
Myocardial Remodeling, Ventricular	low	1
Myocardiopathies	low	1
Nausea	low	3
Necrosis	low	1
Neoplasia	low	6
Neoplasm	low	6
Neoplasm Invasion	low	2
Neoplasm Invasiveness	low	2
Neoplasm Metastases	low	7
Neoplasm Metastasis	low	7
Neoplasms	low	6
Neoplasms, Benign	low	6
Neoplasms, Bladder	low	1
Neoplasms, Breast	low	4
Neoplasms, Cervical	low	2
Neoplasms, Cervix	low	2
Neoplasms, Colonic	low	2
Neoplasms, Colorectal	low	2
Neoplasms, Experimental	low	1
Neoplasms, Experimental Mammary	low	1
Neoplasms, Gastric	low	2
Neoplasms, Hepatic	low	2
Neoplasms, Liver	low	2
Neoplasms, Lung	low	5
Neoplasms, Malignant Epithelial	low	1
Neoplasms, Ovarian	low	1
Neoplasms, Pancreatic	low	4
Neoplasms, Prostate	low	2
Neoplasms, Prostatic	low	2
Neoplasms, Pulmonary	low	5
Neoplasms, Skin	low	3
Neoplasms, Stomach	low	2
Neoplastic Cell Transformation	low	2
Neoplastic Transformation, Cell	low	2
Neovascularization, Pathologic	low	3
Neovascularization, Pathological	low	3
Nephroid Carcinoma	low	2
Neuralgia, Diabetic	low	1
Neuroblastoma	low	2
Non-Small Cell Lung Cancer	low	3
Non-Small Cell Lung Carcinoma	low	3
Non-Small-Cell Lung Carcinoma	low	3
Nonlymphoblastic Leukemia, Acute	low	1
Nonlymphocytic Leukemia, Acute	low	1
Nonsmall Cell Lung Cancer	low	3
Oat Cell Carcinoma of Lung	low	1
Oat Cell Lung Cancer	low	1
Oncogenesis	low	1
Osteoarthritis	low	1
Osteoarthrosis	low	1
Osteoarthrosis Deformans	low	1
Osteoclastic Bone Loss	low	1
Osteogenic Sarcoma	low	2
Osteolysis	low	1
Osteoporosis	low	1
Osteoporosis, Age-Related	low	1
Osteoporosis, Involutional	low	1
Osteoporosis, Post-Traumatic	low	1
Osteoporosis, Senile	low	1
Osteosarcoma	low	2
Osteosarcoma Tumor	low	2
Ovarian Cancer	low	1
Ovarian Neoplasms	low	1
Ovary Cancer	low	1
Ovary Neoplasms	low	1
P388D(1) Leukemia	low	1
Pain	low	1
Pain, Burning	low	1
Pain, Crushing	low	1
Pain, Migratory	low	1
Pain, Radiating	low	1
Pain, Splitting	low	1
Palsy	low	1
Paludism	low	2
Pancreas Cancer	low	4
Pancreas Neoplasms	low	4
Pancreatic Cancer	low	4
Pancreatic Neoplasms	low	4
Papillary Renal Cell Carcinoma	low	2
Paralysis	low	1
Paralysis Agitans	low	1
Parenterally-Transmitted Non-A, Non-B Hepatitis	low	1
Parkinson Disease	low	1
Parkinson Disease, Idiopathic	low	1
Parkinson's Disease	low	1
Parkinson's Disease, Idiopathic	low	1
Parkinson's Disease, Lewy Body	low	1
Pathologic Angiogenesis	low	3
Pathologic Neovascularization	low	3
Plasma Cell Myeloma	low	5
Plasmodium Infections	low	2
Plegia	low	1
Poisoning, Blood	low	1
Poisoning, Carbon Tetrachloride	low	1
Poisoning, CCl4	low	1
Poisoning, Food	low	1
Polio	low	1
Polio Encephalitis	low	1
Poliomyelitis	low	1
Poliomyelitis Infection	low	1
Poliomyelitis, Acute	low	1
Poliomyelitis, Nonpoliovirus	low	1
Poliomyelitis, Preparalytic	low	1
Poultry Diseases	low	1
Primary Myocardial Diseases	low	1
Primary Parkinsonism	low	1
Progranulocytic Leukemia	low	2
Promyelocytic Leukemia, Acute	low	2
Prostate Cancer	low	2
Prostate Neoplasms	low	2
Prostatic Cancer	low	2
Prostatic Neoplasms	low	2
PT-NANBH	low	1
Pulmonary Cancer	low	5
Pulmonary Fibroses	low	1
Pulmonary Fibrosis	low	1
Pulmonary Neoplasms	low	5
Pyaemia	low	1
Pyemia	low	1
Pyohemia	low	1
Remittent Fever	low	2
Renal Carcinoma	low	2
Renal Cell Cancer	low	2
Renal Cell Carcinoma	low	2
Renal Cell Carcinoma, Papillary	low	2
Renal Collecting Duct Carcinoma	low	2
Resistance, Disease	low	1
RNA Virus Infections	low	1
Sarcoma, Osteogenic	low	2
Sarcomatoid Renal Cell Carcinoma	low	2
SARS Coronavirus 2 Infection	low	3
SARS-CoV-2 Infection	low	3
Secondary Myocardial Diseases	low	1
Senile Osteoporosis	low	1
Sepsis	low	1
Septic Shock	low	1
Septicemia	low	1
Severe Sepsis	low	1
Shock, Endotoxic	low	1
Shock, Septic	low	1
Shock, Toxic	low	1
Skin Cancer	low	3
Skin Neoplasms	low	3
Small Cell Cancer Of The Lung	low	1
Small Cell Lung Cancer	low	1
Small Cell Lung Carcinoma	low	1
Small-Cell Lymphoma	low	1
Squamous Cell Carcinoma	low	1
Stomach Cancer	low	2
Stomach Neoplasms	low	2
Suffering, Physical	low	1
Symmetric Diabetic Proximal Motor Neuropathy	low	1
Todd Paralysis	low	1
Todd's Paralysis	low	1
Toxic Hepatitis	low	2
Toxic Shock	low	1
Toxic Shock Syndrome	low	1
Transformation, Neoplastic Cell	low	2
Trichomonas Infections	low	1
Trichomoniasis	low	1
Tumorigenesis	low	1
Tumorigenic Transformation	low	2
Tumors	low	6
Tumors, Breast	low	4
Urinary Bladder Cancer	low	1
Urinary Bladder Neoplasms	low	1
Uterine Cervical Cancer	low	2
Uterine Cervical Neoplasms	low	2
Ventricle Remodeling	low	1
Ventricular Remodeling	low	1
Viral Encephalitis, Japanese B	low	1
Vomiting	low	3
Zika Fever	low	1
Zika Virus Disease	low	1
Zika Virus Infection	low	1
ZikV Infection	low	1

Article	Year
An LC-MS/MS method for the simultaneous determination of lycorine and galanthamine in rat plasma and its application to pharmacokinetic study of Lycoris radiata extract in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Volume: 34, Issue: 6	2014
Study on pharmacokinetic and tissue distribution of lycorine in mice plasma and tissues by liquid chromatography-mass spectrometry. Talanta, Volume: 119	2014
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), Dec-09, Volume: 334, Issue: 6061	2011
Dose-dependent emetic effects of the Amaryllidaceous alkaloid lycorine in beagle dogs. Toxicon : official journal of the International Society on Toxinology, Volume: 57, Issue: 1	2011
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Lycorine inhibits cell proliferation and induced oxidative stress-mediated apoptosis via regulation of the JAK/STAT3 signaling pathway in HT-3 cells. Journal of biochemical and molecular toxicology, Volume: 35, Issue: 10	2021
The inhibitory effect of lycorine on tumor cell apoptosis induced by polymorphonuclear leukocyte-derived calprotectin. Immunopharmacology, Volume: 40, Issue: 2	1998
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Article	Year
Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation, 03-03, Volume: 141, Issue: 9	2020
Antimalarials from nature. Bioorganic & medicinal chemistry, May-01, Volume: 17, Issue: 9	2009
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

lycorine

Description

Related Flora

Cross-References

Synonyms (79)

Research Excerpts

Overview

Effects

Actions

Treatment

Roles (4)

Drug Classes (1)

Pathways (1)

Protein Targets (6)

Potency Measurements

Inhibition Measurements

Biological Processes (14)

Molecular Functions (10)

Ceullar Components (13)

Bioassays (210)

Research

Studies (229)

Study Types

Related Drugs (2,012)

Related Conditions (535)

Research Highlights

Safety/Toxicity (5)

Pharmacokinetics (2)

Bioavailability (2)

Dosage (2)

Natural Sources (2)