oxazoles has been researched along with Hypertension in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (19.29) | 18.7374 |
| 1990's | 66 (47.14) | 18.2507 |
| 2000's | 42 (30.00) | 29.6817 |
| 2010's | 5 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agelis, G; Durdagi, S; Mavromoustakos, T | 1 |
| Davern, PJ; Head, GA; Jackson, KL; Nguyen-Huu, TP; Palma-Rigo, K | 1 |
| Fukumoto, Y; Ito, K; Nawata, J; Onoue, N; Shimokawa, H; Sugimura, K; Tada, T; Wang, H; Zhulanqiqige, D | 1 |
| Bousquet, P; Lessa, MA; Nascimento, AR; Sabino, B; Tibiriçá, E | 1 |
| Ahn, DS; Cho, YE; Lee, YH; Morgan, KG | 1 |
| Imaizumi, S; Miura, S; Saku, K; Uehara, Y; Yahiro, E | 1 |
| Kratochvíl'ová, H; Remková, A | 1 |
| Abdel-Rahman, AA; Zhang, J | 1 |
| Cohen, AF; de Visser, SJ; Nanhekhan, L; Schoemaker, RC; van der Post, JP; van Gerven, JM | 1 |
| Cachofeiro, V; Cediel, E; de las Heras, N; Lahera, V; Navarro-Cid, J; Sanz-Rosa, D; Vázquez-Cruz, B | 1 |
| Widimský, J | 1 |
| Kourilsky, O; Meurin, P | 1 |
| Camilleri, G; Clerson, P; Portal, B; Quiniou, G | 1 |
| Borbás, S; Dienes, BS; Farsang, C; Lengyel, M; Zorándi, A | 1 |
| Bogdański, P; Bryl, W; Cymerys, M; Kujawska-Łuczak, M; Miczke, A; Pupek-Musialik, D | 1 |
| Ayan, F; Ikitimur, B; Koldas, L | 1 |
| Buranakitjaroen, P; Kittipawong, P; Koanantakul, B; Piamsomboon, C; Prasassarakich, N; Silaraks, S; Sukonthasarn, A; Tiyapant, A | 1 |
| Arthur, S; Barrish, J; Baska, RA; Baumann, J; Beyer, S; Bird, E; Carlson, K; Dickinson, K; Fadnis, L; Ferrer, P; Giancarli, M; Gu, Z; Kane, B; Kowala, MC; Macor, JE; Monshizadegan, H; Murugesan, N; Panchal, B; Perrone, M; Ryan, C; Tellew, J; Trippodo, N; Yang, Y; Zhang, D | 1 |
| van Zwieten, PA | 2 |
| Abdel-Rahman, AA; El-Mas, MM | 2 |
| Hefczyc, J; Konieczny, B; Kossmann, S; Szyguła, B; Szyguła, J | 1 |
| Bousquet, P; Greney, H; Monassier, L; Thomas, L | 1 |
| Meredith, PA; Reid, JL | 1 |
| Esler, M; Hastings, J; Jennings, G; Lambert, G; Lux, A; Socratous, F | 1 |
| Cohen, AF; de Visser, SJ; Schoemaker, RC; van der Post, JP; van Gerven, JM | 1 |
| Liebisch, B | 1 |
| Gerová, M; Matusková, J; Pecháòová, O; Török, J | 1 |
| Anichkov, DA; Schastnaya, OV; Shostak, NA | 1 |
| Adamczak, M; Nowak, Ł; Wiecek, A | 1 |
| Briaud, S; Sannajust, F; Zhang, BL | 1 |
| Czarnecka, D; Jaworski, R; Kawecka-Jaszcz, K; Klocek, M; Kucharska, M; Pachocki, R; Zabojszcz, M | 1 |
| Kasherininov, YR; Konrady, AO; Krutikov, AN; Shavarov, AA; Shavarova, EK; Shlyakhto, EV; Smirnova, EV; Vachrameeva, NV | 1 |
| Sirotiaková, J; Widimský, J | 1 |
| Alföldi, S; Elghozi, JL; Farsang, C; Finta, E; Laude, D | 1 |
| Sica, DA | 1 |
| Ogletree, ML; Tesfamariam, B | 1 |
| Laragh, JH | 2 |
| Elliott, HL; MacPhee, G; Panfilov, V; Reid, JL | 1 |
| DeLuca, N; Lorino, G; Rosiello, G; Rubattu, S; Sarno, D; Trimarco, B; Volpe, M | 1 |
| Aparicio, M; Dratwa, M; el Esper, N; Fillastre, JP; Levaltier, B; Lins, R; Meyrier, A; Mignon, F; Ryckelynck, JP; Sennesael, J | 1 |
| Corcoran, C; Coupez, G; Creytens, G; Opsomer, M; Pelemans, W; Van Dessel, A; Verhaeghe, J | 1 |
| Codis, P; Fevrier, B; Pillion, G; Schutz, D | 1 |
| Head, GA; Sannajust, F | 1 |
| Christen, MO; Collins, LA; Dreshaj, I; Ernsberger, P; Graff, LM; Graves, ME; Grove, DL; Haxhiu, MA; Schäfer, SG | 1 |
| Lefebvre, H; Moore, N; Noblet, C; Richard, R; Wolf, LM | 1 |
| Christen, O; Göthert, M; Molderings, GJ; Schäfer, SG | 1 |
| Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM | 1 |
| Ambrosi, P; Lambert, M; Luccioni, R; Scemama, M | 1 |
| Bousquet, P; Bricca, G; Dontenwill, M; Tibiriça, E | 1 |
| Capuana, G; Guillet, C; Indovina, A; Licata, G; Lipari, R; Mazzola, G; Merlino, G; Parrinello, G; Scaglione, R | 1 |
| Luccioni, R | 1 |
| Elghozi, JL; Février, B; Girard, A | 1 |
| Dabire, H; Levy, BI; Poitevin, P; Safar, ME | 1 |
| Argenziano, L; De Luca, N; Iovino, G; Morisco, C; Russo, R; Sarno, D; Trimarco, B; Volpe, M | 1 |
| Beucler, I; Dairou, F; Février, B; Scemama, M | 2 |
| Donnelly, R; Morris, AD; Panfilov, V; Reid, JL | 1 |
| Browne, SE; Macrae, IM | 1 |
| Chudek, J; Nowicki, M; Wiecek, A | 1 |
| Donnelly, R; Morris, AD; Panfilov, V; Reid, JL; Scemama, M | 1 |
| Frishman, WH; Yu, A | 1 |
| Belmonte, A; Fan, NY; Johnson, RA; Lavesa, M; Nasjletti, A; Stier, CT | 1 |
| Johns, EJ; Zhang, T | 1 |
| Berthault, MF; Dubar, M; Ferré, P; Ktorza, A; Morin, J; Pénicaud, L | 2 |
| Cechetto, DF; Kline, RL | 2 |
| Lada, W | 1 |
| DiBona, GF; Gao, H; Welch, WJ; Wilcox, CS | 1 |
| Bond, M; McConnell, BK; Morano, I; Moravec, CS | 1 |
| Dellipizzi, A; Deseyn, K; Mosny, AY; Nasjletti, A; Pucci, ML | 1 |
| Kazaz, C; Sözmen, B; Sözmen, EY; Taşkiran, D; Tüzün, S | 1 |
| Cleary, EW; Dilzer, SC; Huffman, CS; Lasseter, KC; Smith, DA; Watkins, S | 1 |
| Bobik, A; Dilley, R; Kanellakis, P | 1 |
| Balazovjech, I; Dubai, G; Dvorak, I; Januszewicz, W; Krupa-Wojciechowska, B; Kubasik, A; Kuch-Wocial, A; Polak, G; Sadowski, Z; Simon, K; Stejfa, M; Szwed, H | 1 |
| DelliPizzi, A; Nasjletti, A | 1 |
| Kunduzova, OR; Medvedev, OS; Medvedeva, NA; Murashev, AN | 1 |
| Amah, G | 1 |
| Drzewoski, J; Wiśniewska-Jarosińska, M | 1 |
| Bousquet, P; Brasili, L; Bruban, V; Dontenwill, M; Feldman, J; Giannella, M; Greney, H; Pigini, M | 1 |
| Peters, SL; Van Zwieten, PA | 1 |
| Masek, K; Sevcík, J | 1 |
| Bousquet, P; Feldman, J | 1 |
| Robles, NR | 1 |
| Bauduceau, B; Dupuy, O; Mayaudon, H | 3 |
| Polónia, J | 1 |
| Kourilsky, O | 1 |
| Esler, M | 1 |
| Reid, JL | 2 |
| Barrish, JC; Bird, E; Gu, Z; Leith, L; Liu, EC; Marino, A; Mathur, A; Moreland, S; Morrison, RA; Murugesan, N; Spergel, S; Stein, PD; Waldron, T; Webb, ML; Zhang, R | 1 |
| Spinar, J; Vítovec, J | 1 |
| Argenziano, L; De Luca, N; Fontana, D; Iovino, G; Izzo, R; Trimarco, B; Vecchione, C | 1 |
| Schachter, M | 1 |
| Grover, GJ; Rosenfeld, L; Stier, CT | 1 |
| Bousquet, P | 1 |
| Nurminen, ML | 1 |
| Guillet, C; Passeron, J | 1 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Feldman, J; Greney, H; Stutzmann, J; Tibirica, E | 1 |
| Harron, DW | 1 |
| Laurent, S; Safar, M | 1 |
| Macrae, IM; McAuley, MA; Reid, JL | 1 |
| Beevers, DG; Bulpitt, CJ; Dollery, CT; Fletcher, AE; Wilkinson, R | 1 |
| Smits, JF; Struyker-Boudier, HA | 1 |
| De Mey, JG; Eerdmans, PH; Struyker Boudier, HA | 1 |
| Dhib, M; Fillastre, JP | 1 |
| Fillastre, JP | 1 |
| Damase-Michel, C; Dard, B; Macquin-Mavier, I; Montastruc, JL; Tran, MA; Valet, P | 1 |
| Corcoran, C; Mansy, S; Wilkinson, R | 1 |
| Fiorentini, C; Guazzi, M; Guillet, C | 1 |
| Pannier, B; Safar, M | 1 |
| Safar, ME | 2 |
| Callens-el Amrani, F; Paolaggi, F; Swynghedauw, B | 2 |
| Belcourt, A; Bousquet, P; Bricca, G; Dontenwill, M; Feldman, J; Molines, A; Tibirica, E | 1 |
| Dinh Xuan, AT; Lockhart, A | 1 |
| Mahieux, F | 1 |
| Ketelslegers, JM; Lambert, AE; Mpoy, M; Vandeleene, B | 2 |
| Dall, JL | 1 |
| Ausiello, M; Brignoli, M; de Divitiis, O; Di Somma, S; Galderisi, M; Liguori, V; Magnotta, C; Natale, N; Petitto, M | 1 |
| Ehrhardt, JD; Genissel, P; Pozet, N; Singlas, E; Zech, P | 1 |
| Davies, DS; Dollery, CT; Duchier, J; Pannier, B; Safar, ME | 1 |
| Aliot, E; Florentin, J; Gilgenkrantz, JM; Saulnier, JP; Zannad, F | 1 |
| Levy, B; N'guyen van Cao, A; Slama, R | 1 |
| Brisgand, B; Fillastre, JP; Ostermann, G; Schmitt, J | 1 |
| Fillastre, JP; Galinier, F; Le Bihan, G; Letac, B; Schwartz, J | 1 |
| Galley, P; Hessel, JL; Manciet, G; Michel, JP | 1 |
| Beau, B; Brisgand, B; Laurin, S; Mahieux, F; Paraire, M; Vitou, P | 1 |
| Kraupp, O; Stühlinger, W; Turnheim, K | 1 |
| Gallitelli, L; Longhini, E; Santambrogio, S; Sardini, D | 1 |
35 review(s) available for oxazoles and Hypertension
| Article | Year |
|---|---|
AT1 antagonists: a patent review (2008 - 2012).
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Chemistry, Pharmaceutical; Drug Combinations; Drug Discovery; Humans; Hypertension; Models, Molecular; Oxazoles; Patents as Topic; Renin-Angiotensin System; Structure-Activity Relationship | 2013 |
Chymase inhibitors.
Topics: Acetamides; Animals; Atrial Fibrillation; Azetidines; Benzoates; Cardiovascular Diseases; Chymases; Heart Failure; Humans; Hypertension; Mast Cells; Oxazoles; Pyrimidines; Quinazolines; Sulfonamides | 2013 |
Centrally acting imidazoline I1-receptor agonists: do they have a place in the management of hypertension?
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 2001 |
Centrally acting antihypertensive agents: an update.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Guanabenz; Guanfacine; Humans; Hypertension; Imidazoles; Methyldopa; Oxazoles; Rilmenidine | 2007 |
Rilmenidine and the high risk hypertensive patient.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Kidney; Oxazoles; Renin; Rilmenidine; Risk Factors; Sympathetic Nervous System | 1995 |
Clinical pharmacology of drugs acting on imidazoline and adrenergic receptors. Studies with clonidine, moxonidine, rilmenidine, and atenolol.
Topics: Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Clonidine; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Placebos; Receptors, Adrenergic; Receptors, Drug; Reference Values; Rilmenidine | 1995 |
The high-risk hypertensive patient and the potential for brain imidazoline receptor binding by rilmenidine.
Topics: Animals; Brain; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine; Risk Factors | 1994 |
[Imidazole receptors and blood pressure regulation. High receptor selectivity of moxonidine].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Humans; Hypertension; Imidazoles; Oxazoles; Rabbits; Rats; Receptors, Drug; Rilmenidine | 1993 |
[The imidazoline receptor and the central regulation of arterial pressure].
Topics: Blood Pressure; Catecholamines; Central Nervous System; Clonidine; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Adrenergic, alpha; Receptors, Drug; Rilmenidine | 1993 |
[Imidazol receptor agonists--new possibilities for treating hypertension].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1995 |
Imidazoline receptor agonist drugs: a new approach to the treatment of systemic hypertension.
Topics: Animals; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1996 |
From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Rilmenidine | 1996 |
[Imidazoline receptors and use of drug blocking receptors I1].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antihypertensive Agents; Arrhythmias, Cardiac; Cimetidine; Histamine H2 Antagonists; Humans; Hypertension; Imidazoles; Myocardial Infarction; Oxazoles; Rilmenidine | 1996 |
Sympatho-adrenal mechanisms regulating cardiovascular hypertrophy in primary hypertension: a role for rilmenidine?
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Blood Vessels; Cardiomegaly; Humans; Hypertension; Hypertrophy; Norepinephrine; Oxazoles; Rilmenidine; Sympathetic Nervous System | 1998 |
[Clinical pharmacology of hypotensive drugs acting on central imidazoline receptors].
Topics: Antihypertensive Agents; Clonidine; Drug Interactions; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1998 |
Central I1-imidazoline receptors as targets of centrally acting antihypertensive drugs. Clinical pharmacology of moxonidine and rilmenidine.
Topics: Animals; Antihypertensive Agents; Brain; Clinical Trials as Topic; Clonidine; Hemodynamics; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1999 |
[New, modern, centrally active antihypertensive agents in the treatment of essential hypertension].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoles; Medulla Oblongata; Oxazoles; Rilmenidine | 1999 |
Drugs acting on imidazoline receptors: a review of their pharmacology, their use in blood pressure control and their potential interest in cardioprotection.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1999 |
[New perspectives in the treatment of hypertension: the contribution of rilmenidine].
Topics: Antihypertensive Agents; Humans; Hypertension; Oxazoles; Rilmenidine | 2000 |
Clinical benefits of rilmenidine.
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Insulin Resistance; Middle Aged; Multicenter Studies as Topic; Oxazoles; Rilmenidine | 2000 |
The sympathetic system and hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Norepinephrine; Oxazoles; Rilmenidine; Sympathetic Nervous System | 2000 |
Rilmenidine: a clinical overview.
Topics: Albuminuria; Animals; Antihypertensive Agents; Diabetic Angiopathies; Humans; Hyperlipidemias; Hypertension; Hypertrophy, Left Ventricular; Insulin Resistance; Oxazoles; Rilmenidine; Treatment Outcome | 2000 |
Efficacy of rilmenidine, a selective I1 imidazoline receptor binding agent in diabetic hypertensive patients.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Diabetic Angiopathies; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 2000 |
Metabolic effects of moxonidine and other centrally acting antihypertensives.
Topics: Animals; Antihypertensive Agents; Diabetes Complications; Humans; Hypertension; Imidazoles; Insulin Resistance; Metabolism; Oxazoles; Rilmenidine; Sympathetic Nervous System; Sympatholytics; Syndrome | 1999 |
Ifetroban sodium: an effective TxA2/PGH2 receptor antagonist.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Ischemia; Oxazoles; Platelet Aggregation Inhibitors; Prostaglandin H2; Prostaglandins H; Randomized Controlled Trials as Topic; Receptors, Prostaglandin; Receptors, Thromboxane; Stroke; Thrombosis; Thromboxane A2 | 2001 |
I1 receptors, cardiovascular function, and metabolism.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Cardiovascular System; Clonidine; Humans; Hypertension; Imidazoline Receptors; Kidney; Oxazoles; Pancreas; Receptors, Drug; Rilmenidine; Treatment Outcome | 2001 |
Update on rilmenidine: clinical benefits.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Humans; Hypertension; Oxazoles; Rilmenidine; Risk Factors; Treatment Outcome | 2001 |
[Central nervous system as a target for the new antihypertensive agents].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Autonomic Fibers, Preganglionic; Brain; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Medulla Oblongata; Oxazoles; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Sympatholytics | 1999 |
Imidazoline receptors. A new concept in central regulation of the arterial blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Hypertension; Imidazoline Receptors; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine | 1992 |
Distinctive features of rilmenidine possibly related to its selectivity for imidazoline receptors.
Topics: Adrenergic alpha-Agonists; Animals; Chickens; Dogs; Humans; Hypertension; Imidazoline Receptors; Mice; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine | 1992 |
Rilmenidine: a novel approach to first-line treatment of hypertension.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Oxazoles; Rilmenidine | 1992 |
[Current data on the pharmacology of rilmenidine].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Hypnotics and Sedatives; Oxazoles; Rilmenidine; Sympathetic Nervous System | 1989 |
Rilmenidine: a novel antihypertensive agent.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Brain; Humans; Hypertension; Oxazoles; Rilmenidine; Wakefulness | 1989 |
Bronchial effects of alpha 2-adrenoceptor agonists and of other antihypertensive agents in asthma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Asthma; Bronchi; Calcium Channel Blockers; Clonidine; Humans; Hypertension; Oxazoles; Rilmenidine | 1989 |
Rilmenidine and vigilance. Review of clinical studies.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Arousal; Blood Pressure; Double-Blind Method; Humans; Hypertension; Oxazoles; Random Allocation; Rilmenidine; Wakefulness | 1989 |
46 trial(s) available for oxazoles and Hypertension
| Article | Year |
|---|---|
Effect of the new centrally acting antihypertensive agent rilmenidine on endothelial and platelet function in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Platelets; Blood Pressure; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Time Factors; Treatment Outcome | 2002 |
Concentration-effect relationships of two rilmenidine single-dose infusion rates in hypertensive patients.
Topics: Adult; Aged; Analysis of Variance; Confidence Intervals; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Least-Squares Analysis; Male; Middle Aged; Oxazoles; Rilmenidine; Salivation | 2002 |
[Efficacy and tolerance of rilmenidine in patients with mild to moderate hypertension. Results of a Czech and Slovak 6-month multicenter study].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Risk Factors | 2002 |
[Efficacy and acceptability of rilmenidine in a population of 2 738 hypertensive diabetic patients].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Mass Index; Diabetes Complications; Diastole; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Risk Factors; Time Factors | 2002 |
[Comparison of the antihypertensive efficacy of and tolerance to 2 imidazoline receptor agonists: moxonidine and rilmenidine in monotherapy].
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Male; Middle Aged; Oxazoles; Receptors, Drug; Rilmenidine; Severity of Illness Index | 2001 |
[The effect of analysed hypotensive drugs on certain metabolic parameters].
Topics: Adult; Antihypertensive Agents; Diabetes Mellitus, Type 2; Felodipine; Female; Humans; Hyperlipidemias; Hypertension; Hyperuricemia; Indoles; Male; Metabolic Syndrome; Middle Aged; Oxazoles; Rilmenidine | 2003 |
Efficacy and safety of rilmenidine, a selective imidazoline I1 receptor binding ligand, in mild-to-moderate Thai hypertensive patients.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension; Imidazoline Receptors; Ligands; Male; Middle Aged; Oxazoles; Receptors, Drug; Rilmenidine; Thailand; Treatment Outcome | 2003 |
Rilmenidine sympatholytic activity preserves mental stress, orthostatic sympathetic responses and adrenaline secretion.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Oxazoles; Posture; Rilmenidine; Stress, Psychological; Sympathetic Nervous System; Sympatholytics; Tilt-Table Test | 2004 |
Pharmacokinetic/pharmacodynamic assessment of tolerance to central nervous system effects of a 3 mg sustained release tablet of rilmenidine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Delayed-Action Preparations; Drug Administration Schedule; Drug Tolerance; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Pain Measurement; Psychometrics; Reaction Time; Rilmenidine; Saccades; Tablets; Time Factors | 2004 |
Comparison of rilmenidine and lisinopril on ambulatory blood pressure and plasma lipid and glucose levels in hypertensive women with metabolic syndrome.
Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure Monitoring, Ambulatory; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Lisinopril; Metabolic Syndrome; Middle Aged; Oxazoles; Prospective Studies; Rilmenidine; Single-Blind Method; Statistics, Nonparametric; Treatment Outcome | 2005 |
Blockade of sympathetic nervous system activity by rilmenidine increases plasma adiponectin concentration in patients with essential hypertension.
Topics: Adiponectin; Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Oxazoles; Rilmenidine; Sympathetic Nervous System; Time Factors; Treatment Outcome | 2005 |
Rilmenidine--its antihypertensive efficacy, safety and impact on quality of life in perimenopausal women with mild to moderate essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Middle Aged; Oxazoles; Perimenopause; Prospective Studies; Quality of Life; Rilmenidine | 2006 |
How can we block sympathetic overactivity? Effects of rilmenidine and atenolol in overweight hypertensive patients.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Area Under Curve; Atenolol; Brachial Artery; Echocardiography; Female; Glucose Tolerance Test; Humans; Hypertension; Lipids; Male; Middle Aged; Overweight; Oxazoles; Rilmenidine; Statistics, Nonparametric; Sympathetic Nervous System; Treatment Outcome | 2006 |
Effects of one-year treatment with rilmenidine on systemic hypertension-induced left ventricular hypertrophy in hypertensive patients.
Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Echocardiography; Female; Forearm; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Oxazoles; Renin; Rilmenidine; Vascular Resistance | 1994 |
Pharmacokinetics of rilmenidine in patients with chronic renal insufficiency and in hemodialysis patients.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Creatinine; Dialysis Solutions; Female; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Oxazoles; Renal Dialysis; Rilmenidine; Single-Blind Method | 1994 |
Efficacy and safety of rilmenidine in elderly patients--comparison with hydrochlorothiazide. The Belgian Multicentre Study Group.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine | 1994 |
Long-term control of blood pressure by rilmenidine in high-risk populations.
Topics: Age Factors; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Risk Factors | 1994 |
Dose-effect relationship of rilmenidine after chronic administration.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Supine Position | 1993 |
Double-blind controlled study of rilmenidine versus hydrochlorothiazide in mild hypertension: clinical and renal haemodynamic evaluation.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Iodine Radioisotopes; Kidney; Male; Middle Aged; Oxazoles; Regional Blood Flow; Rilmenidine; Time Factors; Vascular Resistance | 1993 |
[Pharmaco-epidemiologic evaluation of rilmenidine in 18,235 hypertensive patients].
Topics: Adult; Aged; Antihypertensive Agents; Drug Administration Schedule; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine | 1995 |
Cardiovascular variability after rilmenidine challenge: assessment of acute dosing effects by means of spectral analysis.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine | 1995 |
Rilmenidine in patients with left ventricular hypertrophy: beyond the reduction of left ventricular mass.
Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Drug Administration Schedule; Electrolytes; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Oxazoles; Renin; Rilmenidine | 1995 |
Lipid profile and antihypertensive efficacy in hyperlipidemic hypertensive patients: comparison of rilmenidine and captopril.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type II; Hypertension; Lipids; Male; Middle Aged; Oxazoles; Rilmenidine | 1995 |
Comparative effects of rilmenidine and atenolol on tests of autonomic function and mental and dynamic exercise in patients with essential hypertension.
Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Atenolol; Autonomic Nervous System; Blood Pressure; Cross-Over Studies; Double-Blind Method; Exercise Test; Heart Rate; Humans; Hypertension; Male; Mental Processes; Middle Aged; Neurosecretory Systems; Oxazoles; Rilmenidine | 1995 |
The effects of rilmenidine and atenolol on mental stress, dynamic exercise and autonomic function in mild to moderate hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Exercise; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Stress, Psychological; Supine Position | 1995 |
[Effects of rilmenidine (hyperium) on lipid balance in hyperlipidemic hypertensive patients. Randomized, controlled, double-blind 8-week study vs. captopril in parallel groups].
Topics: Antihypertensive Agents; Captopril; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; Lipids; Male; Middle Aged; Oxazoles; Rilmenidine; Time Factors | 1996 |
Effect of N-dicyclopropylmethyl-amino-2-oxazoline (S-3341) on antioxidant status and nitric oxide in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxazoles; Rilmenidine; Vitamin E | 1998 |
Pharmacokinetics and pharmacodynamics of zolmitriptan in patients with mild to moderate hypertension: a double-blind, placebo-controlled study.
Topics: Area Under Curve; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxazoles; Oxazolidinones; Serotonin Receptor Agonists; Sodium Chloride Symporter Inhibitors; Tryptamines | 1998 |
Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Double-Blind Method; Echocardiography; Electrocardiography, Ambulatory; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Oxazoles; Rilmenidine; Treatment Outcome | 1998 |
[Essential arterial hypertension treated with rilmenidin : what dose for what patient?].
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Humans; Hypertension; Oxazoles; Rilmenidine | 1999 |
Efficacy of rilmenidine versus captopril on microalbuminuria: a pilot study in hypertensive type 2 diabetics.
Topics: Albuminuria; Antihypertensive Agents; Captopril; Diabetes Mellitus, Type 2; Humans; Hypertension; Oxazoles; Pilot Projects; Random Allocation; Rilmenidine | 1999 |
Rilmenidine in the hypertensive type-2 diabetic: a controlled pilot study versus captopril.
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure Determination; Captopril; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Oxazoles; Pilot Projects; Rilmenidine | 2000 |
Haemodynamic and metabolic effects of rilmenidine in hypertensive patients with metabolic syndrome X. A double-blind parallel study versus amlodipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Body Weight; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Hypertriglyceridemia; Insulin; Male; Middle Aged; Oxazoles; Plasminogen Activator Inhibitor 1; Rilmenidine; Tissue Plasminogen Activator | 2000 |
[Treatment with rilmenidine 1 mg per day: time-lag to maximum response. A multicenter ambulatory study. Le Groupe Français d'étude Multicentrique d'Hyperium].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Placebos; Rilmenidine | 1992 |
The effects of two centrally-acting anti-hypertensive drugs on the quality of life.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Oxazoles; Quality of Life; Rilmenidine | 1991 |
[Effects of rilmenidine on the central nervous system and kidney].
Topics: Antihypertensive Agents; Central Nervous System; Humans; Hypertension; Kidney; Oxazoles; Rilmenidine; Time Factors | 1989 |
[Efficacy and acceptability of rilmenidine in mild to moderate arterial hypertension. A multicenter, randomized, double-blind trial, in comparison with methyldopa in 157 patients].
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Male; Methyldopa; Multicenter Studies as Topic; Oxazoles; Randomized Controlled Trials as Topic; Rilmenidine | 1989 |
[Multicenter, double-blind study comparing rilmenidine 1 mg and hydrochlorothiazide 25 mg in 244 patients].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Oxazoles; Rilmenidine; Time Factors | 1989 |
[Effects of rilmenidine on arterial parameters in essential arterial hypertension].
Topics: Antihypertensive Agents; Arm; Blood Pressure; Double-Blind Method; Hemodynamics; Humans; Hypertension; Middle Aged; Oxazoles; Pulsatile Flow; Randomized Controlled Trials as Topic; Rilmenidine; Vascular Resistance | 1989 |
Rilmenidine and vigilance. Review of clinical studies.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Arousal; Blood Pressure; Double-Blind Method; Humans; Hypertension; Oxazoles; Random Allocation; Rilmenidine; Wakefulness | 1989 |
Effort blood pressure control in the course of antihypertensive treatment.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Exercise Test; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oxazoles; Physical Exertion; Random Allocation; Rest; Rilmenidine | 1989 |
Dose and concentration-effect relations for rilmenidine.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Hypnotics and Sedatives; Male; Oxazoles; Rilmenidine; Saliva; Secretory Rate; Xerostomia | 1988 |
Efficacy and acceptability of rilmenidine for mild to moderate systemic hypertension.
Topics: Adrenergic beta-Agonists; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Random Allocation; Rilmenidine; Xerostomia | 1988 |
A multicenter double-blind comparative study of rilmenidine and clonidine in 333 hypertensive patients.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine | 1988 |
Antihypertensive efficacy and acceptability of rilmenidine in elderly hypertensive patients.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Methyldopa; Oxazoles; Patient Compliance; Random Allocation; Rilmenidine; Supination | 1988 |
Efficacy and safety of rilmenidine for arterial hypertension.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Eye; Female; Glucose; Humans; Hypertension; Lipid Metabolism; Male; Middle Aged; Oxazoles; Random Allocation; Rilmenidine | 1988 |
60 other study(ies) available for oxazoles and Hypertension
| Article | Year |
|---|---|
Actions of rilmenidine on neurogenic hypertension in BPH/2J genetically hypertensive mice.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Atropine; Baroreflex; Blood Pressure; Circadian Rhythm; Heart Rate; Hypertension; Infusions, Intraventricular; Infusions, Subcutaneous; Injections, Intraperitoneal; Male; Medulla Oblongata; Mice; Motor Activity; Oxazoles; Restraint, Physical; Rilmenidine; Stress, Physiological; Sympathetic Nervous System; Sympathomimetics | 2014 |
Enhanced pulsatile pressure accelerates vascular smooth muscle migration: implications for atherogenesis of hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Calcium Signaling; Cell Movement; Cells, Cultured; Dihydropyridines; Disease Models, Animal; Equipment and Supplies; Estrenes; Hypertension; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscle, Smooth, Vascular; Oxazoles; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Tetrazoles; Type C Phospholipases | 2008 |
Microvascular effects of centrally acting antihypertensive drugs in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Clonidine; Disease Models, Animal; Hypertension; Imidazoles; Male; Microcirculation; Microscopy, Video; Muscle, Skeletal; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rilmenidine; Skin; Time Factors | 2010 |
Enhanced contractility and myosin phosphorylation induced by Ca(2+)-independent MLCK activity in hypertensive rats.
Topics: Analysis of Variance; Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Death-Associated Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Male; Marine Toxins; Mesenteric Arteries; Muscle Proteins; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2011 |
The hypotensive action of rilmenidine is dependent on functional N-methyl-D-aspartate receptor in the rostral ventrolateral medulla of conscious spontaneously hypertensive rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Male; Medulla Oblongata; Microinjections; N-Methylaspartate; Oxazoles; Rats; Rats, Inbred SHR; Receptors, N-Methyl-D-Aspartate; Rilmenidine | 2002 |
Role of endothelin-1 and thromboxane A2 in renal vasoconstriction induced by angiotensin II in diabetes and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Oligopeptides; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Thromboxane A2; Vascular Resistance; Vasoconstriction | 2002 |
Value of rilmenidine therapy and its combination with perindopril on blood pressure and left ventricular hypertrophy in patients with essential hypertension (VERITAS).
Topics: Adrenergic alpha-Agonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Echocardiography; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Oxazoles; Perindopril; Rilmenidine | 2003 |
Short-term effects of rilmenidine on left ventricular hypertrophy and systolic and diastolic function in patients with essential hypertension: comparison with an angiotensin converting enzyme inhibitor and a calcium antagonist.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Oxazoles; Rilmenidine; Systole; Ventricular Function, Left | 2003 |
Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcium; Desoxycorticosterone; Disease Models, Animal; Endothelin A Receptor Antagonists; Humans; Hypertension; Irbesartan; Losartan; Male; Oxazoles; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Sodium; Sulfonamides; Tetrazoles | 2004 |
Chronic ethanol administration attenuates imidazoline I1 receptor- or alpha 2-adrenoceptor-mediated reductions in blood pressure and hemodynamic variability in hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Ethanol; Hemodynamics; Hypertension; Imidazoline Receptors; Male; Methyldopa; Motor Activity; Oxazoles; Protein Subunits; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine | 2004 |
[Effect of Rilmenidine(Tenaxum) on the activity of the autonomic nervous system in patients with hypertension and asthma].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Asthma; Autonomic Nervous System; Female; Heart Rate; Humans; Hypertension; Oxazoles; Rilmenidine | 2003 |
Chronic treatment with rilmenidine in spontaneously hypertensive rats: differences between two schedules of administration.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Heart Rate; Hypertension; Infusion Pumps; Injections, Intraperitoneal; Male; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine | 2004 |
Efficacy and tolerability of long-term rilmenidine treatment in hypertensive diabetic patients. A retrospective analysis of a general practice study.
Topics: Adult; Aged; Antihypertensive Agents; Biomarkers; Blood Pressure; Creatinine; Diabetes Mellitus; Diastole; Drug Therapy, Combination; Family Practice; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Oxazoles; Retrospective Studies; Rilmenidine; Systole; Time; Treatment Outcome; Triglycerides | 2004 |
[Case report: hypertension after stroke].
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Basal Ganglia Cerebrovascular Disease; Blood Pressure Monitoring, Ambulatory; Blood Urea Nitrogen; Body Weight; Cerebral Infarction; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypertension; Internal Capsule; Male; Oxazoles; Prognosis; Ramipril; Rilmenidine; Sympathetic Nervous System | 2004 |
Rilmenidine prevents blood pressure increase in rats with compromised nitric oxide production.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Brain; Endothelium, Vascular; Heart Ventricles; Hypertension; Imidazoline Receptors; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxazoles; Rats; Rats, Wistar; Receptors, Drug; Rilmenidine | 2004 |
Central actions of agmatine in conscious spontaneously hypertensive rats.
Topics: Agmatine; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Clonidine; Consciousness; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hypertension; Injections, Intraventricular; Male; Movement; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine | 2005 |
Efficacy and tolerability of rilmenidine compared with isradipine in hypertensive patients with features of metabolic syndrome.
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Double-Blind Method; Drug Tolerance; Female; Humans; Hypertension; Insulin; Isradipine; Lipids; Male; Metabolic Syndrome; Middle Aged; Oxazoles; Rilmenidine | 2006 |
Effects of rilmenidine on 24-h rhythmicity of blood pressure and spontaneous baroreflex sensitivity in essential hypertensive subjects.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Baroreflex; Blood Pressure; Circadian Rhythm; Confounding Factors, Epidemiologic; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Severity of Illness Index; Time Factors; Treatment Outcome | 2006 |
Dissociation of endothelial cell dysfunction and blood pressure in SHR.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Arachidonic Acid; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Endothelium, Vascular; Hypertension; Male; Oxazoles; Propionates; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1995 |
Imidazoline Receptors: A Novel Approach to Hypertension--the Contribution of Rilmenidine. Symposium proceedings. Milan, Italy, June 8, 1993.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1994 |
Involvement of imidazoline-preferring receptors in regulation of sympathetic tone.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Central Nervous System; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Oxazoles; Rabbits; Rats; Rats, Inbred SHR; Receptors, Drug; Rilmenidine | 1994 |
A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonist.
Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Autoradiography; Binding Sites; Blood Pressure; Cattle; Cells, Cultured; Clonidine; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Medulla Oblongata; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha; Receptors, Drug; Rilmenidine | 1994 |
Life-threatening pseudophaeochromocytoma after toloxatone, terbutaline, and phenylephrine.
Topics: Adrenal Gland Neoplasms; Aged; Catecholamines; Diagnosis, Differential; Drug Interactions; Female; Humans; Hypertension; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenylephrine; Pheochromocytoma; Terbutaline; Vasoconstriction | 1993 |
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes | 1993 |
Carotid arterial changes produced by a centrally mediated antihypertensive agent in hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Carotid Arteries; Disease Models, Animal; Heart Rate; Hypertension; Injections, Intravenous; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rilmenidine; Vascular Resistance | 1995 |
Imidazoline Receptors in a Comprehensive Approach to Hypertension. Proceedings of an international symposium. Berlin, Germany, September 10, 1994.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1995 |
Brain structures involved in the hypotensive effects of rilmenidine: evaluation by [14C]2-deoxyglucose autoradiography.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Autoradiography; Azepines; Blood Pressure; Brain; Carbon Radioisotopes; Deoxyglucose; Glucose; Hypertension; Imidazoline Receptors; Male; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine | 1995 |
Effect of ifetroban, a thromboxane A2 receptor antagonist, in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebrovascular Disorders; Genetic Predisposition to Disease; Hypertension; Incidence; Male; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Thromboxane; Survival Analysis; Telemetry | 1996 |
Rilmenidine and reflex renal sympathetic nerve activation in Wistar and hypertensive rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Imidazoline Receptors; Kidney; Male; Oxazoles; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Drug; Reflex; Rilmenidine; Sympathetic Nervous System | 1996 |
[Effects of rilmenidine on rats made insulin resistant and hypertensive by a high fructose diet].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hypertension; Insulin; Insulin Resistance; Oxazoles; Rats; Rats, Wistar; Rilmenidine | 1996 |
Effect of rilmenidine on arterial pressure and urinary output in the spontaneously hypertensive rat.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Food Preferences; Heart Rate; Hypertension; Kidney; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine; Sodium Chloride; Urine | 1997 |
Sympathetic nervous system and hypertension during prolonged TxA2/PGH2 receptor activation in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cardiac Output; Heart Rate; Hexamethonium; Hypertension; Male; Oxazoles; Prazosin; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Sympathetic Nervous System; Thromboxane A2; Time Factors; Vasoconstrictor Agents | 1997 |
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Heart; Heart Ventricles; Hypertension; Isoproterenol; Marine Toxins; Myocardial Contraction; Myocardium; Myosin Light Chains; Norepinephrine; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Troponin I | 1997 |
Contribution of constrictor prostanoids to the calcium-dependent basal tone in the aorta from rats with aortic coarctation-induced hypertension: relationship to nitric oxide.
Topics: Animals; Aorta, Thoracic; Aortic Coarctation; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Endothelium, Vascular; Hypertension; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Oxazoles; Prostaglandins; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1997 |
Ethanol selectively counteracts hypotension evoked by central I(1)-imidazoline but not alpha2-adrenergic receptor activation in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Ethanol; Heart Rate; Hypertension; Imidazoline Receptors; Male; Nordefrin; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine | 1998 |
Complementary antihypertensive action of rilmenidine on the pressure-natriuresis relationship and sodium preference in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Appetite; Blood Pressure; Hypertension; Natriuresis; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine; Sodium Chloride | 1998 |
Rilmenidine normalizes fructose-induced insulin resistance and hypertension in rats.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Fructose; Hypertension; Insulin Resistance; Kinetics; Lipids; Male; Oxazoles; Rats; Rats, Wistar; Reference Values; Rilmenidine | 1998 |
Involvement of nitric oxide and potassium channels in the reduction of basal tone produced by blockade of thromboxane A2/prostaglandin H2 receptors in aortic rings of hypertensive rats.
Topics: 4-Aminopyridine; Animals; Aorta; Basal Metabolism; Bridged Bicyclo Compounds, Heterocyclic; Hypertension; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxazoles; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Tetraethylammonium; Vasodilator Agents | 1998 |
Chronopharmacological dependence of antihypertensive effects of the imidazoline-like drugs in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Circadian Rhythm; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Imidazoles; Male; Motor Activity; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine | 1998 |
An unexpected central hypertensive effect of the new imidazoline compound benazoline.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Imidazoles; Imidazoline Receptors; Male; Nasal Decongestants; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Yohimbine | 1999 |
[New central agents in the treatment of arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Clonidine; Diabetes Complications; Humans; Hypertension; Imidazoles; Nifedipine; Oxazoles; Renin-Angiotensin System; Reserpine; Rilmenidine; Risk Factors; Sympathetic Nervous System; Vasodilator Agents | 1999 |
Biphenylsulfonamide endothelin receptor antagonists. 2. Discovery of 4'-oxazolyl biphenylsulfonamides as a new class of potent, highly selective ET(A) antagonists.
Topics: Administration, Oral; Animals; Biological Availability; Blood Pressure; Carotid Arteries; Drug Evaluation, Preclinical; Endothelin Receptor Antagonists; Hypertension; In Vitro Techniques; Injections, Intravenous; Macaca fascicularis; Muscle Contraction; Muscle, Smooth, Vascular; Oxazoles; Rabbits; Radioligand Assay; Rats; Receptor, Endothelin A; Structure-Activity Relationship; Sulfonamides | 2000 |
[Imidazole receptor agonists--a new advance in the treatment of hypertension?].
Topics: Antihypertensive Agents; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 2000 |
Central cardiovascular effects of rilmenidine and neuropeptide Y in the conscious spontaneously hypertensive rat: haemodynamic and biochemical evidence for a negative interaction.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; In Vitro Techniques; Male; Medulla Oblongata; Neuropeptide Y; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine | 1992 |
Regional hemodynamic effects of rilmenidine and clonidine in the conscious spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Oxazoles; Rats; Rats, Inbred SHR; Renal Circulation; Rilmenidine; Splanchnic Circulation | 1991 |
Contractile reactivity of isolated resistance arteries after 4 weeks of treatment with rilmenidine, clonidine or hydralazine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Clonidine; Hydralazine; Hypertension; In Vitro Techniques; Male; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine; Time Factors; Vasoconstriction | 1991 |
[The 1989 Bichat Conference. A new therapeutic orientation in arterial hypertension: the action of rilmenidine (Hyperium 1 mg) on the so-called imidazoline receptors].
Topics: Antihypertensive Agents; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1990 |
[New discoveries in the regulation of arterial pressure: endazoline, rilmenidine and imidazoline receptors].
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Drug; Rilmenidine | 1989 |
[The heart in patients with hypertension: effects of rilmenidine on experimental cardiac hypertrophy of hypertensive origin in rats].
Topics: Animals; Antihypertensive Agents; Cardiomegaly; Collagen; Heart; Heart Failure; Hypertension; Nephrectomy; Oxazoles; Propranolol; Rats; Rats, Inbred Strains; Rilmenidine | 1989 |
[From alpha 2-adrenergic to endazoline receptors].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Imidazoline Receptors; Oxazoles; Receptors, Adrenergic, alpha; Receptors, Drug; Rilmenidine | 1989 |
Remodelling of the heart in DOCA-salt hypertensive rats by propranolol and by an alpha-2 agonist, rilmenidine.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Desoxycorticosterone; Disease Models, Animal; Heart; Heart Rate; Hypertension; Male; Oxazoles; Propranolol; Rats; Rats, Inbred Strains; Rilmenidine; Sodium Chloride | 1989 |
Second International Symposium on Rilmenidine. Paris, March 11, 1988. Proceedings.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Oxazoles; Rilmenidine | 1989 |
Treatment of hypertension in diabetic patients.
Topics: Antihypertensive Agents; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine | 1989 |
Hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Humans; Hypertension; Oxazoles; Rilmenidine | 1989 |
Pharmacokinetics of rilmenidine.
Topics: Absorption; Administration, Oral; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Female; Humans; Hypertension; Kidney Failure, Chronic; Liver Diseases; Male; Middle Aged; Oxazoles; Rilmenidine | 1988 |
Hemodynamic and electrophysiologic effects of a new alpha 2-adrenoceptor agonist, rilmenidine, for systemic hypertension.
Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Cardiac Output; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Oxazoles; Rilmenidine; Stroke Volume; Time Factors | 1988 |
Noninvasive study of cardiac structure and function after rilmenidine for essential hypertension.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Blood Pressure; Echocardiography; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardium; Oxazoles; Rilmenidine; Stroke Volume; Time Factors; Vascular Resistance | 1988 |
Treatment of systemic hypertension in insulin-treated diabetes mellitus with rilmenidine.
Topics: Adrenergic beta-Agonists; Adult; Aged; Albuminuria; Blood Pressure; Diabetes Mellitus, Type 1; Electrocardiography; Female; Glucose; Humans; Hypertension; Lipid Metabolism; Male; Middle Aged; Oxazoles; Proteinuria; Rilmenidine | 1988 |
[Comparative studies on the effect of Aminorex, ephedrine, noradrenaline, amphetamine, and n-chlorpropylamphetamine on the hemodynamics of the large and small circulatory system in dogs].
Topics: Alkylation; Amines; Amphetamine; Animals; Appetite Depressants; Blood Pressure; Chemical Phenomena; Chemistry; Chlorine; Dogs; Ephedrine; Heart Rate; Hypertension; Lung; Norepinephrine; Oxazoles; Pulmonary Circulation; Sympathomimetics; Vascular Resistance | 1970 |
["Corporeal intracellular pH". Possibilities and significance of its determination in clinical medicine, using the DMO method].
Topics: Acidosis; Adult; Aged; Alkalosis; Animals; Body Fluids; Bronchitis; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Ketones; Male; Mice; Middle Aged; Obesity; Oxazoles; Pulmonary Emphysema; Rabbits | 1968 |