Page last updated: 2024-12-07
5-aminoindole
Description
5-Aminoindole is a heterocyclic compound with potential biological activity. It is an indole derivative with an amino group at the 5-position. 5-Aminoindole has been studied for its potential as a precursor to various biologically active compounds, including pharmaceuticals and agrochemicals. Its synthesis typically involves the reaction of indole with an appropriate amine source, followed by deprotection or other modifications. Research has explored its role in various biological processes, including its interaction with enzymes, its effects on cell signaling, and its potential as an anticancer agent. The compound is also studied for its photophysical properties and its potential in materials science applications.'
5-aminoindole: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
1H-indol-5-amine : An indolamine carrying an amino group at position 5. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 78867 |
| CHEMBL ID | 325916 |
| CHEBI ID | 33067 |
| SCHEMBL ID | 130519 |
| MeSH ID | M0500331 |
Synonyms (52)
| Synonym |
|---|
| AC-5465 |
| BIDD:GT0124 |
| EN300-28737 |
| unii-q732pg0y16 |
| einecs 225-977-2 |
| q732pg0y16 , |
| nsc 61452 |
| SDCCGMLS-0066200.P001 |
| 1h-indol-5-amine |
| 5192-03-0 |
| nsc-61452 |
| nsc61452 |
| indole, 5-amino- |
| 5-aminoindole |
| indol-5-ylamine |
| CHEBI:33067 , |
| 5-aminoindole, 97% |
| A-5640 |
| inchi=1/c8h8n2/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10h,9h2 |
| zcbifhndzbscep-uhfffaoysa- |
| AKOS000280236 |
| CHEMBL325916 |
| A22084 |
| 5-indolamine |
| A-5645 , |
| STK711129 |
| FT-0601203 |
| PS-4506 |
| AM1048 |
| AB00443549-03 |
| SCHEMBL130519 |
| 5 -aminoindole |
| 1h-indol-5-ylamine |
| 5-indole amine |
| 5-amino-indole |
| 1h-indole-5-amine |
| (1h-indole-5-yl)-amine |
| 5amino-1h-indole |
| 5-amino-1h-indole |
| 1h-5-indolylamine |
| 5-amino indole |
| DTXSID5063734 |
| cid_78867 |
| bdbm32210 |
| CS-W007509 |
| mfcd00005679 |
| NCGC00342252-01 |
| SY014519 |
| Q27115500 |
| SB14953 |
| (indol-5-yl)amine |
| Z271138340 |
Drug Classes (1)
| Class | Description |
|---|
| indolamine | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein Targets (2)
Inhibition Measurements
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 22.69
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 22.69 (24.57) | | Research Supply Index | 2.40 (2.92) | | Research Growth Index | 4.51 (4.65) | | Search Engine Demand Index | 21.17 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |