Compounds > sintamil
Page last updated: 2024-11-05

sintamil

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

sintamil: has pronounced sedative properties, but otherwise resembles imipramine; minor descriptor (77-84); on-line & Index Medicus search DIBENZOXAZEPINES (77-84); RN given refers to mono-HCl [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID12195997
MeSH IDM0262778

Synonyms (22)

Synonym
sintamil
16398-39-3
dibenz(b,f)(1,4)oxazepin-11(10h)-one, 10-(3-(dimethylamino)propyl)-2-nitro-, monohydrochloride
nitroxazepine hydrochloride
10-(3-(dimethylamino)propyl)-2-nitrodibenz(b,f)(1,4)oxazepin-11(10h)-one monohydrochloride
einecs 240-449-1
ciba 2330-go
10-(3-(dimethylamino)propyl)-2-nitrobenz(b,f)(1,4)oxazepin-11(10h)-one hydrochloride
unii-y7lu3bj31l
y7lu3bj31l ,
ciba-2330-go
nitroxazepine hydrochloride [who-dd]
10-(3-(dimethylamino)propyl)-2-nitro-dibenz(b,f)(1,4)oxazepin-11(10h)-one monohydrochloride
ciba-2330go
dibenz(b,f)(1,4)oxazepin-11(10h)-one, 10-(3-(dimethylamino)propyl)-2-nitro-, hydrochloride (1:1)
10-[3-(dimethylamino)propyl]-2-nitrodibenz[b,f][1,4]oxazepin-11(10h)-one monohydrochloride
dimethyl-[3-(8-nitro-6-oxobenzo[b][1,4]benzoxazepin-5-yl)propyl]azaniumchloride
DTXSID00936895
10-[3-(dimethylamino)propyl]-2-nitrodibenzo[b,f][1,4]oxazepin-11(10h)-one--hydrogen chloride (1/1)
5-[3-(dimethylamino)propyl]-8-nitrobenzo[b][1,4]benzoxazepin-6-one;hydrochloride
Q27294354
10-(3-(dimethylamino)propyl)-2-nitrodibenzo[b,f][1,4]oxazepin-11(10h)-one hydrochloride
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (11.11%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (11.11%)4.05%
Observational0 (0.00%)0.25%
Other7 (77.78%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
diazepam
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.. diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.		3.37111,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
hydroxyurea
[no description available]		6.9610one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
mitoxantrone
Mitoxantrone: An anthracenedione-derived antineoplastic agent.. mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.		6.9710dihydroxyanthraquinoneanalgesic;
antineoplastic agent
thymidine
[no description available]		1.9710pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Blood Pressure, High
[description not available]		03.3711
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.		03.3711
Granulocytic Leukemia
[description not available]		02.3720
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.		02.3720
Leukemia P388
An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.		01.9710
Experimental Leukemia
[description not available]		01.9710
Acute Liver Injury, Drug-Induced
[description not available]		01.9610
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.		01.9610