pyridoxine has been researched along with Hypertension in 42 studies
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test the effect of vitamin B6 (pyridoxine-HCl, CAS 58-56-0) supplementation on arterial blood pressure in essential hypertension." | 9.08 | Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. ( Aybak, M; Ayyildiz, MO; Karakilçik, AZ; Sermet, A, 1995) |
| "The moderately pyridoxine (vitamin B6)-deficient male rat was introduced by us as an animal model (B6DHT) for the study of hypertension." | 8.80 | Hypertension, calcium channel and pyridoxine (vitamin B6). ( Dakshinamurti, K; Ganguly, PK; Lal, KJ, 1998) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 7.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "The purpose of this study was to test the effect of vitamin B6 (pyridoxine-HCl, CAS 58-56-0) supplementation on arterial blood pressure in essential hypertension." | 5.08 | Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. ( Aybak, M; Ayyildiz, MO; Karakilçik, AZ; Sermet, A, 1995) |
| "The moderately pyridoxine (vitamin B6)-deficient male rat was introduced by us as an animal model (B6DHT) for the study of hypertension." | 4.80 | Hypertension, calcium channel and pyridoxine (vitamin B6). ( Dakshinamurti, K; Ganguly, PK; Lal, KJ, 1998) |
| "Our study confirmed, in a population-based setting, the importance of the known determinants of fasting tHcy and suggested that other dietary and lifestyle factors, including vitamin B-6, riboflavin, alcohol, and caffeine intakes as well as smoking and hypertension, influence circulating tHcy concentrations." | 3.71 | Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. ( Bostom, AG; Jacques, PF; Rich, S; Rosenberg, IH; Selhub, J; Wilson, PW, 2001) |
| " Adult male Sprague-Dawley rats placed on a pyridoxine-deficient diet for 8 weeks showed significant hypertension compared with pyridoxine-supplemented controls." | 3.67 | Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. ( Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL, 1988) |
| "Pyridoxal phosphate has a role in regulating cellular calcium transport through both the voltage-mediated and ATP-mediated purinergic mechanisms of cellular calcium influx and, hence, has a role in the control of hypertension." | 2.52 | Antihypertensive and neuroprotective actions of pyridoxine and its derivatives. ( Dakshinamurti, K; Dakshinamurti, S, 2015) |
| "Pyridoxine pretreatment accelerated DA generation from exogenous DOPA and attenuated the DOPA-induced increases in plasma and urinary DOPA and its metabolite 3-O-methyl-DOPA, but accentuated the increase in free DA and its main metabolites, dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), while BP, ANF, cGMP, PRA, and PA remained unaffected." | 1.29 | Defective 3,4-dihydroxyphenylalanine decarboxylation to dopamine in hydralazine-treated hypertensive patients may be pyridoxine remediable. ( Kuchel, O; Shigetomi, S, 1993) |
| " Reduction of dosage has an equivocal effect on gynaecological side affects-some increase, some decrease." | 1.26 | Human metabolism and steroid contraceptives. Part 2. ( Briggs, MH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (47.62) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 6 (14.29) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, Y | 1 |
| Huang, J | 1 |
| Amoah, AN | 1 |
| Liu, B | 1 |
| Bo, Y | 1 |
| Lyu, Q | 1 |
| Dakshinamurti, S | 1 |
| Dakshinamurti, K | 6 |
| França, CF | 1 |
| Vianna, LM | 1 |
| Shikh, EV | 1 |
| STEIN, SI | 1 |
| NAKAE, R | 1 |
| KAWAMURA, M | 1 |
| Stehouwer, CD | 2 |
| van Guldener, C | 1 |
| Shigetomi, S | 2 |
| Hashimoto, S | 1 |
| Gotoh, M | 1 |
| Ueno, S | 1 |
| Fukuchi, S | 1 |
| Rieder, HP | 1 |
| Berger, W | 1 |
| Fridrich, R | 1 |
| McCarty, MF | 2 |
| Lal, KJ | 4 |
| Kuchel, O | 1 |
| Aybak, M | 1 |
| Sermet, A | 1 |
| Ayyildiz, MO | 1 |
| Karakilçik, AZ | 1 |
| Thliveris, J | 1 |
| Hong, SY | 1 |
| Yang, DH | 1 |
| Chang, SK | 1 |
| Ganguly, PK | 1 |
| de Jong, SC | 1 |
| van den Berg, M | 1 |
| Kostense, PJ | 1 |
| Alders, D | 1 |
| Jakobs, C | 1 |
| Pals, G | 1 |
| Rauwerda, JA | 1 |
| Bender, DA | 1 |
| Morrow, LE | 1 |
| Grimsley, EW | 1 |
| Chait, A | 1 |
| Malinow, MR | 1 |
| Nevin, DN | 1 |
| Morris, CD | 1 |
| Eastgard, RL | 1 |
| Kris-Etherton, P | 1 |
| Pi-Sunyer, FX | 1 |
| Oparil, S | 1 |
| Resnick, LM | 1 |
| Stern, JS | 1 |
| Haynes, RB | 1 |
| Hatton, DC | 1 |
| Metz, JA | 1 |
| Clark, S | 1 |
| McMahon, M | 1 |
| Holcomb, S | 1 |
| Reusser, ME | 1 |
| Snyder, GW | 1 |
| McCarron, DA | 1 |
| Vasdev, S | 2 |
| Ford, CA | 2 |
| Parai, S | 2 |
| Longerich, L | 2 |
| Gadag, V | 2 |
| Wadhawan, S | 1 |
| Boers, GH | 1 |
| Jacques, PF | 1 |
| Bostom, AG | 1 |
| Wilson, PW | 1 |
| Rich, S | 1 |
| Rosenberg, IH | 1 |
| Selhub, J | 1 |
| Tutel'ian, VA | 1 |
| Pogozheva, AV | 1 |
| Rumiantseva, OI | 1 |
| Akol'zina, SE | 1 |
| Lysikova, SL | 1 |
| Kodentsova, VM | 1 |
| Mal'tsev, GIu | 1 |
| Briggs, MH | 2 |
| Podorozhnyĭ, PG | 1 |
| Tomashevskaia, NV | 1 |
| Brophy, MH | 1 |
| Siiteri, PK | 1 |
| Paulose, CS | 1 |
| Packer, S | 1 |
| Stephens, NL | 1 |
| Hunter, KR | 1 |
| Stern, GM | 1 |
| Laurence, DR | 1 |
| Hodges, RE | 1 |
| el-Dakhakhny, M | 1 |
| el-Sayed, M | 1 |
| Yoshimine, N | 1 |
| Kazuya, F | 1 |
| Garcia-Webb, P | 1 |
| Braginskii, BM | 1 |
| Artaeva, LP | 1 |
| Gehlen, W | 1 |
| De Lorenzi, F | 1 |
| Calabrese, L | 1 |
| Montagnani, I | 1 |
| Raskin, NH | 1 |
| Fishman, RA | 1 |
| Buisson, P | 1 |
| Bonerandi, JJ | 1 |
6 reviews available for pyridoxine and Hypertension
| Article | Year |
|---|---|
Antihypertensive and neuroprotective actions of pyridoxine and its derivatives.
Topics: Animals; Antihypertensive Agents; Humans; Hypertension; Neuroprotective Agents; Pyridoxal Phosphate; | 2015 |
Does homocysteine cause hypertension?
Topics: Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Hypertension; Metabolic Syndrome; Pyridoxine | 2003 |
Hypertension, calcium channel and pyridoxine (vitamin B6).
Topics: Animals; Calcium Channels; Disease Models, Animal; Hypertension; Pyridoxine; Vitamin B 6 Deficiency | 1998 |
Non-nutritional uses of vitamin B6.
Topics: Animals; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Glucose Tolerance Test; Homo | 1999 |
Mild hyperhomocysteinemia is an independent risk factor of arterial vascular disease.
Topics: Arteriosclerosis; Case-Control Studies; Clinical Trials as Topic; Comorbidity; Coronary Disease; Fol | 2000 |
Vitamins and hypertension.
Topics: Animals; Humans; Hypertension; Pyridoxine; Vitamin B 6 Deficiency; Vitamin D; Vitamin E | 1992 |
3 trials available for pyridoxine and Hypertension
| Article | Year |
|---|---|
Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; Hyper | 1995 |
Long-term diuretic therapy in hypertensive patients: effects on serum homocysteine, vitamin B6, vitamin B12, and red blood cell folate concentrations.
Topics: Diuretics; Female; Folic Acid; Homocysteine; Humans; Hypertension; Linear Models; Male; Middle Aged; | 1999 |
Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular disease.
Topics: Adult; Aged; Analysis of Variance; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diet; Female; | 1999 |
33 other studies available for pyridoxine and Hypertension
| Article | Year |
|---|---|
Folate, vitamin B
Topics: Adolescent; Adult; Female; Folic Acid; Humans; Hypertension; Male; Middle Aged; Nutrition Surveys; P | 2023 |
Effectiveness of B vitamins on the control of hypertension and stroke events of SHRSP rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Ataxia; Blood Pressure; Dietar | 2010 |
[Urine levels of thiamine and riboflavine in diuretic therapy of patients with cardiovascular diseases].
Topics: Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Pyridoxine; Riboflavin; Thiamine | 2002 |
TREATMENT OF HYPERTENSION IN NEUROPSYCHIATRIC PRACTICE--THE CLINICAL APPLICATION OF L-TRYPTOPHAN.
Topics: Geriatrics; Hypertension; Magnesium Sulfate; Neurotic Disorders; Pyridoxine; Reserpine; Toxicology; | 1963 |
[TRYPTOPHAN METABOLIC DISORDERS].
Topics: Anemia; Biochemical Phenomena; Biochemistry; Blood Chemical Analysis; Child; Humans; Hypertension; H | 1963 |
[A case of vitamin B6 dependent homocystinuria with primary pigmentary degeneration of retina, and cerebral thrombosis].
Topics: Homocystinuria; Humans; Hypertension; Intracranial Embolism and Thrombosis; Male; Middle Aged; Pyrid | 1984 |
[Vitamin status in diabetic neuropathy (thiamine, riboflavin, pyridoxin, cobalamin and tocopherol)].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathies; Diabetic Retinopathy; Female; Huma | 1980 |
Prospects for nutritional control of hypertension.
Topics: Amino Acids; Animals; Chromium; Diet, Sodium-Restricted; Dietary Carbohydrates; Dietary Proteins; Dr | 1981 |
The relationship between low-calcium-induced increase in systolic blood pressure and vitamin B6.
Topics: Animals; Blood Pressure; Calcium, Dietary; Diet; Hypertension; Male; Pyridoxine; Rats; Rats, Sprague | 1995 |
Defective 3,4-dihydroxyphenylalanine decarboxylation to dopamine in hydralazine-treated hypertensive patients may be pyridoxine remediable.
Topics: Adult; Cardiovascular System; Decarboxylation; Dihydroxyphenylalanine; Diuresis; Dopamine; Female; H | 1993 |
The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Hypertension; Male; Pyridoxine; Rats; Rats, Inbred SHR | 1996 |
Plasma homocysteine, vitamin B6, vitamin B12 and folic acid in end-stage renal disease during low-dose supplementation with folic acid.
Topics: Adult; Female; Folic Acid; Homocysteine; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle | 1998 |
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting | 1999 |
Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats.
Topics: Aldehydes; Animals; Antihypertensive Agents; Aorta; Blood Platelets; Blood Pressure; Calcium; Hypert | 1999 |
Dietary vitamin B6 supplementation prevents ethanol-induced hypertension in rats.
Topics: Analysis of Variance; Animals; Blood Pressure Determination; Dietary Supplements; Disease Models, An | 1999 |
Prenatal high-dose pyridoxine may prevent hypertension and syndrome X in-utero by protecting the fetus from excess glucocorticoid activity.
Topics: Dose-Response Relationship, Drug; Female; Fetus; Glucocorticoids; Humans; Hypertension; Infant, Newb | 2000 |
Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Caffeine; Cohort Studies; Creatinine; | 2001 |
[Effects of biologically active supplements on the antioxidant and vitamin status of patients with hypertension and ischemic heart disease].
Topics: Adult; Antioxidants; Ascorbic Acid; beta Carotene; Blood Glucose; Cholesterol; Dietary Supplements; | 2001 |
Human metabolism and steroid contraceptives. Part 2.
Topics: Ascorbic Acid; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dose-Response Relationship, Dr | 1977 |
[Vitamin B 6 balance in hypertensive disease].
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Pyridoxine; Vitamin B 6 Deficiency | 1976 |
Pyridoxal phosphate and hypertensive disorders of pregnancy.
Topics: Administration, Oral; Brain; Female; Fetus; Growth; Humans; Hypertension; Infant, Newborn; Injection | 1975 |
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat.
Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepi | 1988 |
Use of levodopa with other drugs.
Topics: Adult; Aged; Antidepressive Agents; Antiemetics; Digoxin; Dihydroxyphenylalanine; Diuretics; Drug An | 1970 |
Nutrition and "the pill".
Topics: Chlormadinone Acetate; Contraceptives, Oral; Demography; Dimethisterone; Ethynodiol Diacetate; Femal | 1971 |
The effect of some drugs on oxalic acid excretion in urine.
Topics: Ascorbic Acid; Aspirin; Asthma; Calcium; Citrates; Coronary Disease; Depression, Chemical; Diabetes | 1970 |
[Influence of vitamin B6 on L-aromatic amino acid decarboxylase in the organs of spontaneously hypertensive rats (SHR)].
Topics: Animals; Brain; Dopa Decarboxylase; Hypertension; Kidney; Liver; Pyridoxine; Rats; Vitamin B 6 Defic | 1974 |
Letter: Hypertension and depression.
Topics: Antidepressive Agents; Contraceptives, Oral; Depression; Female; Humans; Hypertension; Pyridoxine | 1973 |
[Pyridoxine adequacy in atherosclerotic cardiosclerosis and hypertension].
Topics: Alanine Transaminase; Arteriosclerosis; Aspartate Aminotransferases; Coronary Disease; Humans; Hyper | 1973 |
[Differential treatment of Parkinson's disease, with special reference to the possibility of iatrogenic disorders (author's transl)].
Topics: Amantadine; Anesthetics; Anti-Bacterial Agents; Antidepressive Agents; Antihypertensive Agents; Anti | 1974 |
[Action of a taurine-nucleotide-vitamin association on carbohydrate metabolism].
Topics: Adult; Aged; Arteriosclerosis; Biliary Tract Diseases; Carbohydrate Metabolism; Coronary Disease; Di | 1971 |
[Use in geriatrics of an association of taurine, nucleotides and vitamins].
Topics: Adult; Aged; Arteriosclerosis; Cerebrovascular Disorders; Dementia; Female; Hemiplegia; Humans; Hype | 1970 |
Pyridoxine-deficiency neuropathy due to hydralazine.
Topics: Female; Humans; Hydralazine; Hypertension; Middle Aged; Paresthesia; Pyridoxine; Tryptophan; Urine; | 1965 |
[The use of pyridophylline in a cardiology department].
Topics: Aged; Aortic Diseases; Arrhythmias, Cardiac; Arteritis; Coronary Disease; Female; Heart Diseases; Hu | 1966 |