Adiponectin receptor protein 2

An adiponectin receptor protein 2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q86V24]

Progestin and adipoQ receptor family member 2;
Progestin and adipoQ receptor family member II

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
amikacin	Homo sapiens (human)	Kd	3.1000	1	1

This protein enables 6 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
identical protein binding	molecular function	Binding to an identical protein or proteins. [GOC:jl]
metal ion binding	molecular function	Binding to a metal ion. [GOC:ai]
adiponectin binding	molecular function	Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism. [GOC:BHF, GOC:rl, PMID:15210937]
adipokinetic hormone receptor activity	molecular function	Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis. [GOC:sart, PMID:11904407]
signaling receptor activity	molecular function	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. [GOC:bf, GOC:signaling]

This protein is located in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is active in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is involved in 6 target(s):

Target	Category	Definition
hormone-mediated signaling pathway	biological process	The series of molecular signals mediated by the detection of a hormone. [GOC:sm]
fatty acid oxidation	biological process	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. [ISBN:0198506732, MetaCyc:FAO-PWY]
adiponectin-activated signaling pathway	biological process	The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:20536390]
glucose homeostasis	biological process	Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. [GOC:go_curators]
vascular wound healing	biological process	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. [GOC:BHF, GOC:dph]
positive regulation of cold-induced thermogenesis	biological process	Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis. [PMID:27876809]