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n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Hypertension

n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide has been researched along with Hypertension in 9 studies

N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide: structure given in first source
NS-398 : A C-nitro compound that is N-methylsulfonyl-4-nitroaniline bearing an additional cyclohexyloxy substituent at position 2.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"The present study was designed to analyse whether hypertension alters the involvement of cyclooxygenase-2-derived mediators in phenylephrine-induced vasoconstrictor responses."7.73Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses. ( Alonso, MJ; Alvarez, Y; Balfagón, G; Briones, AM; Salaices, M, 2005)
"The present study was designed to analyse whether hypertension alters the involvement of cyclooxygenase-2-derived mediators in phenylephrine-induced vasoconstrictor responses."3.73Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses. ( Alonso, MJ; Alvarez, Y; Balfagón, G; Briones, AM; Salaices, M, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Briones, AM3
Alonso, MJ3
Hernanz, R2
Tovar, S1
Vila, E2
Salaices, M3
Okumura, T1
Hayashi, I1
Ikezawa, T1
Yamanaka, M1
Takata, T1
Fujita, Y1
Saigenji, K1
Yamashina, S1
Majima, M1
Tomida, T1
Numaguchi, Y1
Nishimoto, Y1
Tsuzuki, M1
Hayashi, Y1
Imai, H1
Matsui, H1
Okumura, K1
Zewde, T1
Mattson, DL1
Bratz, IN1
Kanagy, NL1
Alvarez, Y1
Balfagón, G1
Adeagbo, AS1
Zhang, X1
Patel, D1
Joshua, IG1
Wang, Y1
Sun, X1
Igbo, IN1
Oriowo, MA1
Gluais, P1
Lonchampt, M1
Morrow, JD1
Vanhoutte, PM1
Feletou, M1

Other Studies

9 other studies available for n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide and Hypertension

ArticleYear
Hypertension alters the participation of contractile prostanoids and superoxide anions in lipopolysaccharide effects on small mesenteric arteries.
    Life sciences, 2002, Sep-13, Volume: 71, Issue:17

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 2; Dexamethasone; Dose-Response Rel

2002
Cyclooxygenase-2 inhibitors attenuate increased blood pressure in renovascular hypertensive models, but not in deoxycorticosterone-salt hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:6

    Topics: Animals; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxyge

2002
Inhibition of COX-2 prevents hypertension and proteinuria associated with a decrease of 8-iso-PGF2alpha formation in L-NAME-treated rats.
    Journal of hypertension, 2003, Volume: 21, Issue:3

    Topics: Animals; Base Sequence; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Di

2003
Hypertension alters role of iNOS, COX-2, and oxidative stress in bradykinin relaxation impairment after LPS in rat cerebral arteries.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:1

    Topics: Animals; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Arteries; Cyclooxygenase 2; C

2004
Inhibition of cyclooxygenase-2 in the rat renal medulla leads to sodium-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 44, Issue:4

    Topics: Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; H

2004
Nitric oxide synthase-inhibition hypertension is associated with altered endothelial cyclooxygenase function.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyg

2004
Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses.
    Journal of hypertension, 2005, Volume: 23, Issue:4

    Topics: Animals; Aorta; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost;

2005
Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension.
    Journal of hypertension, 2005, Volume: 23, Issue:5

    Topics: Animals; Aorta; Cyclooxygenase 2; Desoxycorticosterone; Endothelium, Vascular; Hypertension; Indomet

2005
Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin.
    British journal of pharmacology, 2005, Volume: 146, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, T

2005