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albuterol and Hypertension

albuterol has been researched along with Hypertension in 38 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the effects of an osmotic release oral drug delivery system of metoprolol on the changes induced by cumulative doses of inhaled salbutamol on bronchomotor tone, skeletal muscle, and the circulatory system after single (day 1) and multiple (day 7) dosing in 18 hypertensive asthmatic patients (forced expiratory volume in 1 second > 50% predicted; diastolic blood pressure > 90 mm Hg)."9.07Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors. ( Bauer, K; Kaik, B; Kaik, G, 1994)
"The cardioselectivity and hypotensive properties of the beta 1-specific beta-blocker bisoprolol were investigated using a single-dose comparison of 10 and 20 mg bisoprolol, 100 mg atenolol, and placebo in 12 hypertensive asthmatic patients."9.06The cardioselective and hypotensive effects of bisoprolol in hypertensive asthmatics. ( Chatterjee, SS, 1986)
"We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs."9.06Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989)
"Twenty patients with inadequately controlled hypertension were treated with 4 mg doxazosin ER daily for 16 weeks as an adjunct to their existing antihypertensive regimen."7.74Add-on therapy with doxazosin in patients with hypertension influences arterial stiffness and albuterol-mediated arterial vasodilation. ( Adamska, K; Guzik, P; Krauze, T; Milewska, A; Wykretowicz, A; Wysocki, H, 2007)
"Fourteen patients with uncomplicated essential hypertension and mild asthma were treated with Atenolol 50-125 mg/day for up to 8 months."7.67Treatment of hypertension in mild asthmatic patients with atenolol. ( Clement, S; Grizotzki, B; Krauss, A; Krauss, S; Spitz, E, 1984)
"This study investigated the effects of an osmotic release oral drug delivery system of metoprolol on the changes induced by cumulative doses of inhaled salbutamol on bronchomotor tone, skeletal muscle, and the circulatory system after single (day 1) and multiple (day 7) dosing in 18 hypertensive asthmatic patients (forced expiratory volume in 1 second > 50% predicted; diastolic blood pressure > 90 mm Hg)."5.07Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors. ( Bauer, K; Kaik, B; Kaik, G, 1994)
"The cardioselectivity and hypotensive properties of the beta 1-specific beta-blocker bisoprolol were investigated using a single-dose comparison of 10 and 20 mg bisoprolol, 100 mg atenolol, and placebo in 12 hypertensive asthmatic patients."5.06The cardioselective and hypotensive effects of bisoprolol in hypertensive asthmatics. ( Chatterjee, SS, 1986)
"We compared the frequency and severity of cardiac arrhythmias during combined oral theophylline and inhaled salbutamol vs."5.06Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias. ( Huikuri, H; Korhonen, UR; Linnaluoto, M; Poukkula, A, 1989)
"Twenty patients with inadequately controlled hypertension were treated with 4 mg doxazosin ER daily for 16 weeks as an adjunct to their existing antihypertensive regimen."3.74Add-on therapy with doxazosin in patients with hypertension influences arterial stiffness and albuterol-mediated arterial vasodilation. ( Adamska, K; Guzik, P; Krauze, T; Milewska, A; Wykretowicz, A; Wysocki, H, 2007)
"Fourteen patients with uncomplicated essential hypertension and mild asthma were treated with Atenolol 50-125 mg/day for up to 8 months."3.67Treatment of hypertension in mild asthmatic patients with atenolol. ( Clement, S; Grizotzki, B; Krauss, A; Krauss, S; Spitz, E, 1984)
" The potency and efficacy of isoproterenol (ISO) in these arteries were decreased in SHR before and during the development of hypertension as compared with age-matched Wistar Kyoto rats (WKY)."3.67Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension. ( Aoki, K; Asano, M; Dohi, Y; Fujimoto, S; Matsuda, T, 1987)
"Practolol treatment induced a significant BP reduction, while the addition of salbutamol failed to give any further decrease."2.64Antihypertensive effect of beta-1 receptor blockade and beta-2-receptor stimulation in essential hypertension. ( Andersson, O; Berglund, G, 1975)
"A total of 77,480 newly-diagnosed COPD patients with a mean age of 68."1.40The association between inhaled long-acting bronchodilators and less in-hospital care in newly-diagnosed COPD patients. ( Kim, J; Kim, K; Kim, Y; Kim, YS; Lee, CK; Lee, JH; Lee, SD; Lee, SW; Oh, YM; Park, YB; Yoo, KH; Yoon, HK, 2014)
"A total of 203 patients with chronic obstructive pulmonary diseases (COPD) with normal blood pressure (BP) as well as with systemic arterial hypertension of different character (labile and stable pulmonogenic essential hypertension) were examined."1.27[Chronic obstructive lung diseases associated with systemic arterial hypertension]. ( Konovalov, VI; Kubyshkin, VF; Soldatchenko, SS, 1985)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199021 (55.26)18.7374
1990's7 (18.42)18.2507
2000's5 (13.16)29.6817
2010's3 (7.89)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Faconti, L1
Farukh, B1
McNally, RJ1
Brett, S1
Chowienczyk, PJ1
Bailey, MA1
Tikkakoski, AJ1
Kangas, P1
Suojanen, L1
Tahvanainen, AM1
Eräranta, A1
Kähönen, MAP1
Sipilä, K1
Mustonen, JT1
Pörsti, IH1
Kim, J1
Kim, K1
Kim, Y1
Yoo, KH1
Lee, CK1
Yoon, HK1
Kim, YS1
Park, YB1
Lee, JH1
Oh, YM1
Lee, SD1
Lee, SW1
Somes, J1
Donatelli, NS1
Waring, WS1
Sinclair, HM1
Webb, DJ1
Chipps, B1
Wykretowicz, A1
Guzik, P1
Krauze, T1
Adamska, K1
Milewska, A1
Wysocki, H1
Dusseau, JW3
Smith, TL1
Hutchins, PM3
Kawasaki, H1
Cline, WH1
Su, C1
Borkowski, KR2
Quinn, P2
Krauss, S1
Spitz, E1
Krauss, A1
Grizotzki, B1
Clement, S1
Whitehead, MI1
Mander, AM1
Hertogs, K1
Williams, RM1
Pettingale, KW1
Svensson, TH1
Almgren, O1
Dahlöf, C1
Elam, M1
Engberg, G1
Hallberg, H1
Thorén, P1
Gardiner, SM2
March, JE2
Kemp, PA2
Bennett, T2
Bauer, K1
Kaik, G1
Kaik, B1
Wang, YX1
Poon, KS1
Randall, DJ1
Pang, CC1
Beenen, OH1
Batink, HD1
Pfaffendorf, M1
van Zwieten, PA1
Desai, MY1
De la Peña-Almaguer, E1
Mannting, F1
Peng, Y1
Ma, S1
Zhang, S1
Li, Y1
Yang, L1
Bian, S1
Mancini, G1
Mannino, F1
Nomura, T1
Palmer, GC2
Greenberg, S1
Salvetti, A1
Poli, L1
Arzilli, F1
Sassano, L1
Pedrinelli, R1
Motolese, M1
Andersson, O1
Berglund, G1
Kirby, RF1
Woodworth, CH1
Woodworth, GG1
Johnson, AK1
Wood, AJ1
Brearley, CJ1
Aronson, JK1
Grahame-Smith, DG1
Chatterjee, SS1
Poukkula, A1
Korhonen, UR1
Huikuri, H1
Linnaluoto, M1
Kubyshkin, VF1
Soldatchenko, SS1
Konovalov, VI1
Fujimoto, S1
Dohi, Y1
Aoki, K1
Asano, M1
Matsuda, T1
Spence, JD1
Wong, DG1

Trials

7 trials available for albuterol and Hypertension

ArticleYear
Effects of salbutamol and glyceryl trinitrate on large arterial stiffness are similar between patients with hypertension and adults with normal blood pressure.
    British journal of clinical pharmacology, 2006, Volume: 62, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Albuterol; Arteries; Blood Pressure; Female; Humans; Hypertension;

2006
Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Adult; Albuterol; Asthma; Atenolol; Double-

1994
Antihypertensive effect of beta-1 receptor blockade and beta-2-receptor stimulation in essential hypertension.
    Acta medica Scandinavica, 1975, Volume: 197, Issue:6

    Topics: Albuterol; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate;

1975
The effect of oral salbutamol on cation transport measured in vivo in healthy volunteers.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:3

    Topics: Administration, Oral; Adult; Albuterol; Biological Transport; Bipolar Disorder; Chlorides; Erythrocy

1990
The cardioselective and hypotensive effects of bisoprolol in hypertensive asthmatics.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 11

    Topics: Adrenergic beta-Antagonists; Aged; Albuterol; Asthma; Bisoprolol; Blood Pressure; Bronchial Provocat

1986
Theophylline and salbutamol in combination in patients with obstructive pulmonary disease and concurrent heart disease: effect on cardiac arrhythmias.
    Journal of internal medicine, 1989, Volume: 226, Issue:4

    Topics: Aged; Albuterol; Arrhythmias, Cardiac; Clinical Trials as Topic; Delayed-Action Preparations; Drug T

1989
Amiloride with or without salbutamol versus placebo: effects on lipoproteins in hypertensive patients treated with timolol-hydrochlorothiazide.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:5

    Topics: Albuterol; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazi

1986

Other Studies

31 other studies available for albuterol and Hypertension

ArticleYear
Impaired β 2 -adrenergic endothelium-dependent vasodilation in patients previously hospitalized with coronavirus disease 2019.
    Journal of hypertension, 2023, 06-01, Volume: 41, Issue:6

    Topics: Adrenergic Agents; Albuterol; COVID-19; Endothelium, Vascular; Humans; Hypertension; Male; Sildenafi

2023
Salbutamol and salt-sensitive hypertension.
    Kidney international, 2021, Volume: 100, Issue:2

    Topics: Albuterol; Animals; Humans; Hypertension; Kidney Tubules, Distal; Mice; Sodium Chloride; Sodium Chlo

2021
Salbutamol-induced Decrease in Augmentation Index is Related to the Parallel Increase in Heart Rate.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:2

    Topics: Administration, Inhalation; Administration, Sublingual; Adrenergic beta-2 Receptor Agonists; Adult;

2018
The association between inhaled long-acting bronchodilators and less in-hospital care in newly-diagnosed COPD patients.
    Respiratory medicine, 2014, Volume: 108, Issue:1

    Topics: Administration, Inhalation; Aged; Albuterol; Bronchodilator Agents; Delayed-Action Preparations; Dis

2014
A geriatric patient with medication-mediated profound weakness.
    Journal of emergency nursing, 2010, Volume: 36, Issue:6

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Anti-Arrhythmia Agents; Anticonvulsants; Antihyperte

2010
Systemic reaction to omalizumab.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:2

    Topics: Acetates; Adrenal Cortex Hormones; Aged; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents;

2006
Add-on therapy with doxazosin in patients with hypertension influences arterial stiffness and albuterol-mediated arterial vasodilation.
    British journal of clinical pharmacology, 2007, Volume: 64, Issue:6

    Topics: Albuterol; Delayed-Action Preparations; Doxazosin; Drug Therapy, Combination; Humans; Hypertension;

2007
Acute effects of salbutamol on arteriolar vasodilatation and blood pressure in spontaneously hypertensive rats.
    Microvascular research, 1981, Volume: 22, Issue:1

    Topics: Albuterol; Amyl Nitrite; Animals; Arteries; Blood Pressure; Heart Rate; Hypertension; Muscles; Propr

1981
Enhanced presynaptic beta adrenoceptor-mediated modulation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3

    Topics: Adrenergic beta-Antagonists; Albuterol; Animals; Blood Pressure; Blood Vessels; Electric Stimulation

1982
Facilitation by beta-adrenoreceptors of stimulation-induced vasoconstriction in pithed spontaneously hypertensive rats.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:2

    Topics: Adrenalectomy; Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Decerebrate State; Elec

1984
Adrenaline and the development of genetic hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Albuterol; Animals; Blood Pressure; Delayed-Action Pre

1984
Elevated arteriolar adenosine 3',5'-cyclic monophosphate production by SHR.
    The American journal of physiology, 1982, Volume: 243, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Animals; Arterioles; Blood Pressure; Body Weight; Cyclic AMP

1982
Treatment of hypertension in mild asthmatic patients with atenolol.
    Angiology, 1984, Volume: 35, Issue:12

    Topics: Adult; Albuterol; Asthma; Atenolol; Blood Pressure; Electrocardiography; Exercise Test; Female; Hear

1984
Acute congestive cardiac failure in a hypertensive woman receiving salbutamol for premature labour.
    British medical journal, 1980, May-17, Volume: 280, Issue:6225

    Topics: Adult; Albuterol; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Methyldopa

1980
Cardiac failure in a hypertensive woman receiving salbutamol for premature labour.
    British medical journal, 1980, Jul-19, Volume: 281, Issue:6234

    Topics: Albuterol; Female; Heart Failure; Humans; Hypertension; Obstetric Labor, Premature; Pregnancy; Pregn

1980
alpha- and beta-adrenoreceptor-mediated control of brain noradrenaline neurons and antihypertensive therapy.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Action Potentials; Albuterol; Animals; Brain; Clonidine; Dopamine; Hypertension; Locus Coeruleus; Ma

1980
Resting cardiovascular status and vasodilator function in a vasopressin-deficient, hypertensive strain of rat.
    Journal of hypertension, 1994, Volume: 12, Issue:11

    Topics: Acetylcholine; Albuterol; Animals; Blood Pressure; Bradykinin; Disease Models, Animal; Hemodynamics;

1994
Endothelium-derived nitric oxide partially mediates salbutamol-induced vasodilatations.
    European journal of pharmacology, 1993, Dec-21, Volume: 250, Issue:3

    Topics: Albuterol; Animals; Aorta; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Endothelium,

1993
Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments.
    Blood pressure, 1997, Volume: 6, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiotoni

1997
The contribution of nitric oxide to cardiovascular status and responses to vasodilators in conscious, hypertensive, transgenic ((mRen-2)27) rats.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Acetylcholine; Adrenergic beta-Agonists; Albuterol; Animals; Animals, Genetically Modified; Antihype

1998
Can pre-treatment with beta-agonists reduce stress test time and the use of atropine in dobutamine stress testing?
    Cardiology, 2001, Volume: 95, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Albuterol; Atropine; Coronary Disease; D

2001
Clinical significance of changes in beta-adrenoreceptors in peripheral lymphocytes in patients with essential hypertension.
    Chinese medical journal, 2000, Volume: 113, Issue:12

    Topics: Adrenergic beta-Agonists; Adult; Aged; Albuterol; Binding, Competitive; Blood Pressure; Dose-Respons

2000
[Side-effects of beta-adrenergic drugs].
    Minerva medica, 1976, Mar-13, Volume: 67, Issue:15

    Topics: Adrenergic beta-Agonists; Albuterol; Angina Pectoris; Arrhythmias, Cardiac; Headache; Humans; Hypert

1976
Central beta-adrenergic receptors for blood pressure regulation in spontaneously hypertensive rats.
    Japanese journal of pharmacology, 1976, Volume: 26, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Depression, Chemical; Hypertension; Me

1976
Alterations in myocardial adenylate cyclase in spontaneously hypertensive rats.
    Pharmacology, 1979, Volume: 19, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Catecholamines; Clonidine; Glucagon

1979
Effects of salbutamol and metoprolol on plasma renin activity and plasma potassium of normal subjects and of hypertensive patients.
    Journal of endocrinological investigation, 1978, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Albuterol; Female; Hemodynamics; Humans; Hyperaldosteronism; Hypertension; Male;

1978
Stimulation of arteriolar number by salbutamol in spontaneously hypertensive rats.
    The American journal of physiology, 1979, Volume: 236, Issue:1

    Topics: Albuterol; Animals; Arteries; Arterioles; Blood Pressure; Heart Rate; Hematocrit; Hypertension; Musc

1979
Diminished adenylate cyclase responses in frontal cortex and cerebral capillaries of spontaneously hypertensive rats.
    Biochemical pharmacology, 1979, Sep-15, Volume: 28, Issue:18

    Topics: Adenylyl Cyclases; Albuterol; Animals; Capillaries; Cerebral Cortex; Cerebrovascular Circulation; Do

1979
Beta-2 adrenoceptor mediated vasodilation: role in cardiovascular responses to acute stressors in spontaneously hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:5

    Topics: Albuterol; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Dose-Response Rel

1991
[Chronic obstructive lung diseases associated with systemic arterial hypertension].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combina

1985
Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension.
    European journal of pharmacology, 1987, Apr-14, Volume: 136, Issue:2

    Topics: Albuterol; Animals; Arteries; Dinoprost; Hydroxydopamines; Hypertension; Isoproterenol; Male; Nitrop

1987