| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| sk&f-38393 | [no description available] | medium | 13 | 0 | benzazepine;
catechols;
secondary amino compound | |
| 4-hydroxy-2-nonenal | [no description available] | medium | 1 | 0 | 4-hydroxynon-2-enal;
4-hydroxynonenal | |
| colforsin | [no description available] | medium | 4 | 0 | acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol | adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist |
| guanylyl imidodiphosphate | [no description available] | medium | 5 | 0 | nucleoside triphosphate analogue | |
| corticosterone | [no description available] | medium | 1 | 0 | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite |
| arginine vasopressin | [no description available] | medium | 2 | 0 | vasopressin | cardiovascular drug;
hematologic agent;
mitogen |
| 2'-iodospiperone | [no description available] | medium | 2 | 0 | | |
| spiperone | [no description available] | medium | 6 | 0 | aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound | alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist |
| oxytocin | [no description available] | medium | 1 | 0 | heterodetic cyclic peptide;
peptide hormone | oxytocic;
vasodilator agent |
| vasotocin | [no description available] | medium | 1 | 0 | | |
| vasotocin, (beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)-o-methyl-tyr(2)-thr(4)-orn(8)-tyr(9)-nh2 | [no description available] | medium | 1 | 0 | | |
| antalarmin | [no description available] | medium | 1 | 0 | pyrrolopyrimidine;
tertiary amino compound | corticotropin-releasing factor receptor antagonist |
| pyrroles | [no description available] | medium | 1 | 0 | pyrrole;
secondary amine | |
| ncq 298 | [no description available] | medium | 6 | 0 | | |
| fluorides | [no description available] | medium | 1 | 0 | halide anion;
monoatomic fluorine | |
| aluminum fluoride | [no description available] | medium | 1 | 0 | aluminium coordination entity | |
| epidepride | [no description available] | medium | 1 | 0 | dimethoxybenzene | |
| ascorbic acid | [no description available] | medium | 1 | 0 | ascorbic acid;
vitamin C | coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent |
| edetic acid | [no description available] | medium | 1 | 0 | ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid | anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector |
| sulpiride | [no description available] | medium | 10 | 0 | benzamides;
N-alkylpyrrolidine;
sulfonamide | antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist |
| pindolol | [no description available] | medium | 2 | 0 | indoles;
secondary amine | antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent |
| isoproterenol | [no description available] | medium | 2 | 0 | catechols;
secondary alcohol;
secondary amino compound | beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent |
| fenoldopam | [no description available] | medium | 3 | 0 | benzazepine | alpha-adrenergic agonist;
antihypertensive agent;
dopamine agonist;
dopaminergic antagonist;
vasodilator agent |
| chloramine-t | [no description available] | medium | 1 | 0 | organic sodium salt | allergen;
antifouling biocide;
disinfectant |
| sodium iodide | [no description available] | medium | 1 | 0 | inorganic sodium salt;
iodide salt | |
| adenosine | [no description available] | medium | 1 | 0 | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent |
| caffeine | [no description available] | medium | 1 | 0 | purine alkaloid;
trimethylxanthine | adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic |
| n(6)-cyclopentyladenosine | [no description available] | medium | 1 | 0 | | |
| isoleucine | [no description available] | medium | 1 | 0 | aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| arginine | [no description available] | medium | 1 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
| phenylalanine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid | algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| butaclamol | [no description available] | medium | 2 | 0 | | |
| cocaine | [no description available] | medium | 3 | 0 | benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid | adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic |
| sincalide | [no description available] | medium | 2 | 0 | oligopeptide | |
| dizocilpine maleate | [no description available] | medium | 1 | 0 | maleate salt;
tetracyclic antidepressant | anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist |
| 7-hydroxy-2-n,n-dipropylaminotetralin | [no description available] | medium | 1 | 0 | tetralins | |
| domperidone | [no description available] | medium | 2 | 0 | benzimidazoles;
heteroarylpiperidine | antiemetic;
dopaminergic antagonist |
| iodosulpride | [no description available] | medium | 5 | 0 | | |
| quinpirole | [no description available] | medium | 2 | 0 | pyrazoloquinoline | dopamine agonist |
| ethylmaleimide | [no description available] | medium | 2 | 0 | maleimides | anticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor |
| vanoxerine | [no description available] | medium | 1 | 0 | ether;
N-alkylpiperazine;
organofluorine compound;
tertiary amino compound | dopamine uptake inhibitor |
| raclopride | [no description available] | medium | 2 | 0 | salicylamides | |
| melatonin | [no description available] | medium | 1 | 0 | acetamides;
tryptamines | anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger |
| lead | [no description available] | medium | 1 | 0 | carbon group element atom;
elemental lead;
metal atom | neurotoxin |
| 1,3-dipropyl-8-cyclopentylxanthine | [no description available] | medium | 1 | 0 | oxopurine | adenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor |
| triazoles | [no description available] | medium | 1 | 0 | 1,2,3-triazole | |
| bucladesine | [no description available] | medium | 1 | 0 | 3',5'-cyclic purine nucleotide | |
| 1-methyl-3-isobutylxanthine | [no description available] | medium | 1 | 0 | 3-isobutyl-1-methylxanthine | |
| clozapine | [no description available] | medium | 2 | 0 | benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound | adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic |
| haloperidol | [no description available] | medium | 2 | 0 | aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol | antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist |
| nandrolone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid | human metabolite |
| nandrolone decanoate | [no description available] | medium | 1 | 0 | steroid ester | |
| 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | [no description available] | medium | 1 | 0 | methylpyridines;
phenylpyridine;
tetrahydropyridine | neurotoxin |
| hydroxyindoleacetic acid | [no description available] | medium | 2 | 0 | indole-3-acetic acids | drug metabolite;
human metabolite;
mouse metabolite |
| 3,4-dihydroxyphenylacetic acid | [no description available] | medium | 2 | 0 | catechols;
dihydroxyphenylacetic acid | human metabolite |
| desipramine | [no description available] | medium | 1 | 0 | dibenzoazepine;
secondary amino compound | adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor |
| homovanillic acid | [no description available] | medium | 2 | 0 | guaiacols;
monocarboxylic acid | human metabolite;
mouse metabolite |
| gbr 12935 | [no description available] | medium | 1 | 0 | ether;
N-alkylpiperazine;
tertiary amino compound | dopamine uptake inhibitor |
| apomorphine | [no description available] | medium | 2 | 0 | aporphine alkaloid | alpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug |
| bromocriptine | [no description available] | medium | 2 | 0 | indole alkaloid | antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist |
| mazindol | [no description available] | medium | 1 | 0 | organic molecular entity | |
| hemicholinium 3 | [no description available] | medium | 1 | 0 | | |
| benzamide | [no description available] | medium | 1 | 0 | benzamides | |
| ketanserin | [no description available] | medium | 1 | 0 | aromatic ketone;
organofluorine compound;
piperidines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist |
| 3-hydroxybenzylhydrazine | [no description available] | medium | 1 | 0 | phenols | |
| hydrazine | [no description available] | medium | 1 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
| gamma-aminobutyric acid | [no description available] | medium | 1 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
| levodopa | [no description available] | medium | 1 | 0 | amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid | allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug |
| oxidopamine | [no description available] | medium | 4 | 0 | benzenetriol;
catecholamine;
primary amino compound | drug metabolite;
human metabolite;
neurotoxin |
| g(m1) ganglioside | [no description available] | medium | 1 | 0 | alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide | |
| putrescine | [no description available] | medium | 1 | 0 | alkane-alpha,omega-diamine | antioxidant;
fundamental metabolite |
| siagoside | [no description available] | medium | 1 | 0 | lactone;
sialotetraosylceramide | |
| a 68930 | [no description available] | medium | 1 | 0 | 2-benzopyran | |
| ibotenic acid | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | neurotoxin |
| biotin | [no description available] | medium | 1 | 0 | biotins;
vitamin B7 | coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite |
| dihydroxyphenylalanine | [no description available] | medium | 1 | 0 | hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | human metabolite |
| papaverine | [no description available] | medium | 1 | 0 | benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines | antispasmodic drug;
vasodilator agent |
| a 69024 | [no description available] | medium | 1 | 0 | | |
| eedq | [no description available] | medium | 1 | 0 | | |
| 3-n-methylspiperone | [no description available] | medium | 1 | 0 | aromatic ketone | |
| guanosine triphosphate | [no description available] | medium | 1 | 0 | guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor |
| flupenthixol | [no description available] | medium | 1 | 0 | thioxanthenes | |
| quinolinic acid | [no description available] | medium | 2 | 0 | pyridinedicarboxylic acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist |
| ym 09151-2 | [no description available] | medium | 1 | 0 | N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide | |
| 1h-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- | [no description available] | medium | 1 | 0 | benzazepine | |
| ergoline | [no description available] | medium | 1 | 0 | diamine;
ergoline alkaloid;
indole alkaloid fundamental parent;
indole alkaloid;
organic heterotetracyclic compound | |
| 1-methyl-4-phenylpyridinium | [no description available] | medium | 1 | 0 | pyridinium ion | apoptosis inducer;
herbicide;
human xenobiotic metabolite;
neurotoxin |
| 1-propanol | [no description available] | medium | 1 | 0 | propan-1-ols;
short-chain primary fatty alcohol | metabolite;
protic solvent |