4-cresol has been researched along with Hypertension in 1 studies
4-cresol: RN given refers to parent cpd
p-cresol : A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A practical enantioselective synthesis of renin inhibitor MK-1597 (ACT-178882), a potential new treatment for hypertension, is described." | 3.77 | A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate. ( Abele, S; Angelaud, R; Cameron, M; Corley, E; Funel, JA; Krska, S; Lau, S; Molinaro, C; O'Shea, PD; Roy, A; Shultz, S; Steinhuebel, D; Trinh, T; Weisel, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Molinaro, C | 1 |
| Shultz, S | 1 |
| Roy, A | 1 |
| Lau, S | 1 |
| Trinh, T | 1 |
| Angelaud, R | 1 |
| O'Shea, PD | 1 |
| Abele, S | 1 |
| Cameron, M | 1 |
| Corley, E | 1 |
| Funel, JA | 1 |
| Steinhuebel, D | 1 |
| Weisel, M | 1 |
| Krska, S | 1 |
1 other study available for 4-cresol and Hypertension
| Article | Year |
|---|---|
A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.
Topics: Catalysis; Cresols; Cyclopropanes; Enzyme Inhibitors; Hydrogenation; Hypertension; Molecular Structu | 2011 |