alprenolol has been researched along with Hypertension in 113 studies
Alprenolol: One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.
alprenolol : A secondary alcohol that is propan-2-ol substituted by a 2-allylphenoxy group at position 1 and an isopropylamino group at position 3. It is a beta-adrenergic antagonist used as a antihypertensive, anti-arrhythmia and a sympatholytic agent.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Women with previously untreated arterial hypertension have been followed up during ten years of beta-blocker treatment, first for three years with alprenolol and then for seven years with the selective beta1-blocker metoprolol." | 9.05 | Seven years on a selective beta-blocker - metoprolol. A long-term study of women with arterial hypertension. ( Bengtsson, C, 1981) |
| "A double-blind cross-over comparison of the antihypertensive actions of alprenolol and pindolol in equipotent doses was carried out in 22 patients with moderately severe essential hypertension." | 9.04 | Twice-daily pindolol and alprenolol in essential hypertension of moderate severity. ( Hartikainen, M; Heikkilä, J, 1976) |
| "In 7 young men with essential hypertension, central and regional hemodynamics and leg metabolism were studied at rest, during and after a prolonged exercise, and with and without long-term alprenolol treatment." | 9.04 | Influence of alprenolol on hemodynamic and metabolic responses to prolonged exercise in subjects with hypertension. ( Frisk-Holmberg, M; Jorfeldt, L; Juhlin-Dannfeldt, A, 1977) |
| "The antihypertensive effect of two adrenergic blocking agents (Alprenolol and Propranolol) have been studied in a group of 107 patients with essential hypertension." | 9.04 | Effect of beta adrenergic blocking agents (alprenolol and propranolol) in essential hypertension. ( Khakpour, M; Nik-Akhtar, B; Rashed, MA, 1975) |
| "The clinical benefits and hemodynamic effects of continuous alprenolol infusion for control of hypertension in the acute stage of ruptured cerebral aneurysms were investigated." | 7.68 | Continuous alprenolol infusion for control of hypertension in the acute stage of ruptured intracranial aneurysms. ( Karasawa, J; Shibamoto, K; Shishido, H; Touho, H; Yamada, K, 1991) |
| "The binding of 3H-dihydroalprenolol, a beta-antagonist, with the fat cell plasma membrane was studied in spontaneously hypertensive rats and in patients with essential hypertension." | 7.66 | [Characteristics of 3H-dihydroalprenolol binding to beta-receptors in the fat cells of rats and spontaneous genetic hypertension and in hypertensive disease]. ( Boriskina, GM; Postnov, IuV, 1980) |
| "A case of alprenolol-induced thrombocytopenia in a 65-year-old woman is reported." | 7.66 | Alprenolol-induced thrombocytopenia. ( Magnusson, B; Rödjer, S, 1980) |
| "Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol." | 7.65 | Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976) |
| "The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension." | 7.65 | Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975) |
| "In 25 patients with essential hypertension, the renal plasma flow RPF), glomerular filtration rate (GFR) and BP have been measured before and after one month's treatment with alprenolol." | 7.65 | Glomerular filtration rate and renal plasma flow in patients with essential hypertension before and after treatment with alprenolol. ( Pedersen, EB, 1975) |
| "105 patients with previously untreated hypertension entered the trial and 72 completed it." | 6.65 | Double-blind comparison of metoprolol, alprenolol, and oxprenolol in hypertension. ( Nissinen, A; Tuomilehto, J, 1979) |
| " Steady-state alprenolol concentrations were determined from the area under the plasma concentration-time curve during one eight-hour dosage interval after treatment for six weeks." | 5.26 | Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. I. Relationship between plasma concentration and adrenergic beta-receptor blockade. ( Collste, P; Frisk-Holmberg, M; Haglund, K; Rawlins, MD, 1976) |
| " During long-term use alpha-methyldopa frequently reduces the total peripheral resistance and the reduction in cardiac output is usually modest, at rest as well as during exercise." | 5.26 | alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects. ( Lund-Johansen, P, 1978) |
| "Women with previously untreated arterial hypertension have been followed up during ten years of beta-blocker treatment, first for three years with alprenolol and then for seven years with the selective beta1-blocker metoprolol." | 5.05 | Seven years on a selective beta-blocker - metoprolol. A long-term study of women with arterial hypertension. ( Bengtsson, C, 1981) |
| "A double-blind cross-over comparison of the antihypertensive actions of alprenolol and pindolol in equipotent doses was carried out in 22 patients with moderately severe essential hypertension." | 5.04 | Twice-daily pindolol and alprenolol in essential hypertension of moderate severity. ( Hartikainen, M; Heikkilä, J, 1976) |
| "082 (atenolol or Tenormin), alone or in combination with other drugs for treatment of hypertension in a total of 104 patients, including 15 with a chronic obstructive lung disease." | 5.04 | Long-term clinical experience with atenolol--a new selective beta-1-blocker with few side-effects from the central nervous system. ( Henningsen, NC; Mattiasson, I, 1979) |
| "The antihypertensive effect of two adrenergic blocking agents (Alprenolol and Propranolol) have been studied in a group of 107 patients with essential hypertension." | 5.04 | Effect of beta adrenergic blocking agents (alprenolol and propranolol) in essential hypertension. ( Khakpour, M; Nik-Akhtar, B; Rashed, MA, 1975) |
| "In a double blind study including 24 patients with essential hypertension the beta-blocking agent Timolol showed a mild antihypertensive effect." | 5.04 | [Antihypertensive therapy with a new beta-blocking agent Timolol. Double blind study and comparison with Alprenolol and Pindolol (author's transl)]. ( Heinze, A; Werth, HW; Wessels, F, 1977) |
| "In 7 young men with essential hypertension, central and regional hemodynamics and leg metabolism were studied at rest, during and after a prolonged exercise, and with and without long-term alprenolol treatment." | 5.04 | Influence of alprenolol on hemodynamic and metabolic responses to prolonged exercise in subjects with hypertension. ( Frisk-Holmberg, M; Jorfeldt, L; Juhlin-Dannfeldt, A, 1977) |
| "To determine whether there are differences in cardiac beta-adrenoceptor responsiveness, isoprenaline affinity constants and fractional beta-adrenoceptor occupancy-response relationships for isoprenaline in the early stages of established hypertension, we studied the effects of bromoacetylalprenololmenthane (BAAM) and ([3,5-diamino-6-chloro-N-(1[N-beta-(2-hydroxyl-3-alpha-naphthoxypropy lamino)ethylcarbamoyl]-1-methylethyl)-pyrazine-2-carboxamide (ICI 147 798), slowly reversible beta-adrenoceptor antagonists, on the isoprenaline responses of the left ventricular papillary muscle and the left and right atria of 6-month-old Wistar Kyoto rats (WKY) and spontaneously hypertensive rats (SHR)." | 3.70 | Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats. ( Barnett, CW; Doggrell, SA; Petcu, EB, 1998) |
| "The clinical benefits and hemodynamic effects of continuous alprenolol infusion for control of hypertension in the acute stage of ruptured cerebral aneurysms were investigated." | 3.68 | Continuous alprenolol infusion for control of hypertension in the acute stage of ruptured intracranial aneurysms. ( Karasawa, J; Shibamoto, K; Shishido, H; Touho, H; Yamada, K, 1991) |
| " Propranolol, acebutolol and practolol, at a daily dose of 50 mg/kg, prevented the occurrence of hypertension, not only during the 4 weeks of treatment, but also during 6,9 and 11 weeks respectively after cessation of treatment." | 3.66 | Variability in the preventive action of the B-blockers on genetic hypertension in the rat. ( Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP, 1980) |
| "The binding of 3H-dihydroalprenolol, a beta-antagonist, with the fat cell plasma membrane was studied in spontaneously hypertensive rats and in patients with essential hypertension." | 3.66 | [Characteristics of 3H-dihydroalprenolol binding to beta-receptors in the fat cells of rats and spontaneous genetic hypertension and in hypertensive disease]. ( Boriskina, GM; Postnov, IuV, 1980) |
| "A case of alprenolol-induced thrombocytopenia in a 65-year-old woman is reported." | 3.66 | Alprenolol-induced thrombocytopenia. ( Magnusson, B; Rödjer, S, 1980) |
| "Muscle biopsies from the vastus muscle were taken at rest and immediately after upright bicycle exercise at 50% of the individual VO2max, before and during 6 wk of alprenolol treatment (200 to 400 mg twice daily) in 6 untrained patients with essential hypertension." | 3.66 | Metabolic changes in muscle on long-term alprenolol therapy. ( Frisk-Holmberg, M; Jorfeldt, L; Juhlin-Dannfelt, A; Karlsson, J, 1979) |
| "The long-term haemodynamic effects of treatment with mefruside alone or in combination with alprenolol have been studied in nine patients with essential hypertension." | 3.65 | Haemodynamic effects of saluretic treatment and beta-receptor blockade in patients with essential hypertension. ( Bevegård, S; Castenfors, J; Danielson, M, 1977) |
| "Plasma renin concentration (PRC) was measured in 46 patients with essential hypertension before and after treatment for 4 weeks with alprenolol 600-1200 mg daily." | 3.65 | Plasma renin concentration in essential hypertension during beta-adrenergic blockade and vasodilator therapy. ( Kornerup, HJ; Pedersen, EB, 1977) |
| "Plasma aldosterone concentration (PAC), plasma renin concentration (PRC), plasma potassium, plasma sodium and blood pressure (BP) have been measured in 22 patients with essential hypertension before and after treatment for one month with alprenolol." | 3.65 | Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment. ( Kornerup, HJ; Pedersen, EB, 1976) |
| "In 25 patients with essential hypertension, the renal plasma flow RPF), glomerular filtration rate (GFR) and BP have been measured before and after one month's treatment with alprenolol." | 3.65 | Glomerular filtration rate and renal plasma flow in patients with essential hypertension before and after treatment with alprenolol. ( Pedersen, EB, 1975) |
| "The effect of alprenolol alone and in combination with hydralazine on plasma renin concentration has been studied in 25 patients with arterial hypertension." | 3.65 | Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension. ( Kornerup, HJ; Pedersen, EB, 1975) |
| "Alprenolol was given in the form of a slow-release tablet preparation at a dosage of 200 mg twice daily." | 2.65 | Placebo-controlled, double-blind clinical trial of alprenolol in African hypertensive patients. ( Aderounmu, AF; Falase, AO; Salako, LA, 1979) |
| "105 patients with previously untreated hypertension entered the trial and 72 completed it." | 2.65 | Double-blind comparison of metoprolol, alprenolol, and oxprenolol in hypertension. ( Nissinen, A; Tuomilehto, J, 1979) |
| "2." | 2.64 | Effect of long-term anti-hypertensive beta-receptor-blocking treatment on haemodynamic and metabolic responses to prolonged exercise in man. ( Aström, H; Frisk-Holmberg, M; Jorfeldt, L; Juhlin-Dannfeldt, A, 1976) |
| " Steady-state alprenolol concentrations were determined from the area under the plasma concentration-time curve during one eight-hour dosage interval after treatment for six weeks." | 1.26 | Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. I. Relationship between plasma concentration and adrenergic beta-receptor blockade. ( Collste, P; Frisk-Holmberg, M; Haglund, K; Rawlins, MD, 1976) |
| "Propranolol did not cause this pressor effect in prehypertensive (seven week old) SHRs." | 1.26 | Beta-adrenergic receptor blocking drugs in spontaneous hypertension. ( Levy, JV, 1976) |
| " During long-term use alpha-methyldopa frequently reduces the total peripheral resistance and the reduction in cardiac output is usually modest, at rest as well as during exercise." | 1.26 | alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects. ( Lund-Johansen, P, 1978) |
| "Treatment with alprenolol, a beta-adrenergic blocking agent, did not influence noradrenaline and adrenaline in plasma in the basal state or the urinary excretion of the three catecholamines." | 1.25 | Catecholamines in plasma and urine in patients with essential hypertension determined by double-isotope derivative techniques. ( Christensen, NJ; Pedersen, EB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 107 (94.69) | 18.7374 |
| 1990's | 5 (4.42) | 18.2507 |
| 2000's | 1 (0.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krasnikova, TL | 1 |
| Radiukhin, VA | 1 |
| Il'inskiĭ, OB | 1 |
| Shkhvatsabaia, IK | 1 |
| Parfenova, EV | 1 |
| Jack, DB | 1 |
| Dean, S | 1 |
| Kendall, MJ | 1 |
| Laugher, S | 1 |
| Weber, MA | 1 |
| Drayer, JI | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Bengtsson, C | 6 |
| de Clavière, M | 1 |
| Heyndrickx, JP | 1 |
| Brotelle, R | 1 |
| Colot, M | 1 |
| Lund-Johansen, P | 2 |
| Ostman, J | 5 |
| Zoler, ML | 1 |
| Frishman, WH | 1 |
| Furberg, CD | 1 |
| Friedewald, WT | 1 |
| England, JF | 1 |
| Boriskina, GM | 2 |
| Postnov, IuV | 1 |
| Ochiai, T | 1 |
| Watanabe, K | 1 |
| Nishijima, H | 1 |
| Hayashi, R | 1 |
| Sato, H | 1 |
| Takagi, T | 1 |
| Mikami, K | 1 |
| Nishikawa, T | 1 |
| Tamura, Y | 1 |
| Kumagai, A | 1 |
| Kofod, P | 1 |
| Kjaer, K | 1 |
| Vejlø, S | 1 |
| Hvidt, S | 1 |
| Arner, P | 1 |
| Haglund, K | 6 |
| Juhlin-Dannfelt, A | 2 |
| Nowak, J | 1 |
| Wennlund, A | 1 |
| Seideman, P | 2 |
| Grahnén, A | 1 |
| Lindström, B | 1 |
| Von Bahr, C | 2 |
| Takakuwa, H | 1 |
| Myers, MM | 1 |
| Whittemore, SR | 1 |
| Hendley, ED | 1 |
| Magnusson, B | 1 |
| Rödjer, S | 1 |
| Doggrell, SA | 4 |
| Surman, AJ | 1 |
| Mistry, DN | 1 |
| Henderson, CJ | 1 |
| Petcu, EB | 1 |
| Barnett, CW | 1 |
| Chen, YY | 1 |
| Heinze, A | 2 |
| Wessels, F | 2 |
| Losse, H | 1 |
| Collste, P | 3 |
| Frisk-Holmberg, M | 6 |
| Rawlins, MD | 4 |
| Levy, JV | 1 |
| Hansson, L | 3 |
| Werkö, L | 5 |
| Guédon, J | 1 |
| Lucsko, M | 1 |
| Chaignon, M | 1 |
| Aubert, Ph | 1 |
| Sivertsson, R | 1 |
| Sannerstedt, R | 3 |
| Fanchamps, A | 1 |
| Tannenbaum, H | 1 |
| Eliasson, K | 1 |
| Lins, LE | 1 |
| Sundqvist, K | 1 |
| Prichard, BN | 1 |
| Louis, WJ | 1 |
| Rand, MJ | 1 |
| McNeil, JJ | 1 |
| Drummer, O | 1 |
| Jarrott, B | 1 |
| Davy, M | 2 |
| Cohen, Y | 2 |
| Wepierre, J | 2 |
| Limas, C | 2 |
| Limas, CJ | 2 |
| Meurer, KA | 1 |
| Frisch, P | 1 |
| Charnilas, J | 1 |
| Blum, I | 1 |
| Eisenberg, N | 1 |
| Atsmon, A | 1 |
| Jorfeldt, L | 3 |
| Juhlin-Dannfeldt, A | 2 |
| Werth, HW | 1 |
| Henningsen, NC | 1 |
| Mattiasson, I | 1 |
| Tuomilehto, J | 3 |
| Nissinen, A | 1 |
| Salako, LA | 1 |
| Falase, AO | 1 |
| Aderounmu, AF | 1 |
| Talseth, T | 1 |
| Fauchald, P | 2 |
| Pape, JF | 2 |
| Karlsson, J | 1 |
| Midol-Monnet, M | 1 |
| Bevegård, S | 2 |
| Castenfors, J | 3 |
| Danielson, M | 2 |
| Pytte, R | 1 |
| Zanozdra, NS | 1 |
| Nazarenko, VR | 1 |
| Caviet, NL | 1 |
| Klaassen, CH | 1 |
| Hartikainen, M | 1 |
| Heikkilä, J | 1 |
| Coope, J | 1 |
| Comerford, MB | 2 |
| Pringle, A | 2 |
| Bertilsson, L | 1 |
| Ringberger, VA | 1 |
| Sjöqvist, F | 2 |
| Pedersen, EB | 6 |
| Kornerup, HJ | 3 |
| Mogensen, CE | 1 |
| Orme, ML | 1 |
| Aström, H | 1 |
| Vedin, A | 2 |
| Wilhelmson, C | 1 |
| Iisalo, E | 1 |
| Lehtonen, A | 1 |
| Nik-Akhtar, B | 1 |
| Rashed, MA | 1 |
| Khakpour, M | 1 |
| Christensen, NJ | 1 |
| Abramova, VG | 1 |
| Touho, H | 1 |
| Karasawa, J | 1 |
| Shishido, H | 1 |
| Yamada, K | 1 |
| Shibamoto, K | 1 |
| Bompart, J | 1 |
| Pastor, G | 1 |
| Giral, L | 1 |
| Alvart, R | 1 |
| Prikryl, P | 1 |
| Kunovská, V | 1 |
| Rysánek, K | 1 |
| Vondrácek, V | 1 |
| Prásek, J | 1 |
| Borg, KO | 1 |
| Gross, F | 1 |
| Lawrence, T | 1 |
| Frankl, WS | 1 |
| Erikssen, J | 1 |
| Storm-Mathisen, H | 1 |
| Johnsson, G | 3 |
| Nyberg, G | 1 |
| Offerhaus, L | 1 |
| Harrison, DC | 1 |
| Simpson, FO | 1 |
| Cottier, P | 1 |
| Stenberg, J | 2 |
| Wilhelmsson, C | 1 |
| Gysling, E | 1 |
| Roba, J | 1 |
| Lambelin, G | 1 |
| De Schaepdryver, AF | 1 |
| von Egidy, H | 1 |
| Lind, M | 1 |
| Johnsson, H | 1 |
| Orö, L | 1 |
| Pape, J | 2 |
| Vedin, JA | 2 |
| Wilhelmsson, CE | 2 |
| Eisalo, A | 1 |
| Heino, A | 1 |
| Munter, J | 1 |
| Angervall, G | 1 |
| Bystedt, U | 1 |
| Somer, T | 1 |
| Luomanmäki, K | 1 |
| Frick, MH | 1 |
| Puska, P | 1 |
| Mustaniemi, H | 1 |
| Bergstrand, RH | 1 |
| Farsang, C | 1 |
| Nagy, Z | 1 |
| Berglund, G | 1 |
| Naess, K | 1 |
| Hallbäck, M | 1 |
| Folkow, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for alprenolol and Hypertension
| Article | Year |
|---|---|
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
beta-adrenergic blockade and diabetes mellitus. A review.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; D | 1983 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
Beta-adrenergic blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Brain; Dose-Response Relationship, | 1977 |
[Preventive effects of beta-blockers on myocardial infarction and on cardiac accidents following a first infarct].
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Humans; Hy | 1978 |
[Long-term utilization of beta-blockers in arterial hypertension].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Toleranc | 1978 |
Beta-adrenoceptor-blocking agents in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Brain; Cardiac Output; Drug Evaluation; Hea | 1979 |
[Therapy and differential therapy with beta sympathicolytic drugs].
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Arrhythmias, Cardiac; Cardiomyopathy, Hype | 1975 |
Blood pressure in the elderly.
Topics: Aged; Aging; Alprenolol; Cardiovascular Diseases; Humans; Hypertension; Methyldopa; United Kingdom | 1976 |
Beta-adrenergic receptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Aortic Aneurysm; Aortic Valve; Arrhythmias | 1973 |
[Clinical application of beta-blockaders].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Anxiety Diso | 1973 |
Beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Antidepressive Agents; Antihy | 1974 |
[Beta adrenergic drugs in arterial hypertension].
Topics: Action Potentials; Adrenergic beta-Antagonists; Alprenolol; Antihypertensive Agents; Blood Pressure; | 1972 |
40 trials available for alprenolol and Hypertension
| Article | Year |
|---|---|
Seven years on a selective beta-blocker - metoprolol. A long-term study of women with arterial hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Drug Therapy, Combination; Female | 1981 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
The influence of beta blockers upon plasma cyclic AMP levels.
Topics: Alprenolol; Cyclic AMP; Humans; Hypertension; Middle Aged; Pindolol; Propranolol | 1980 |
Labetalol and alprenolol. A comparative investigation of antihypertensive effect.
Topics: Adult; Aged; Alprenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamine | 1980 |
Effect of metoprolol and alprenolol on the metabolic, hormonal, and haemodynamic response to insulin-induced hypoglycaemia in hypertensive, insulin-dependent diabetics.
Topics: Adult; Alprenolol; Diabetes Complications; Diabetes Mellitus; Female; Hemodynamics; Humans; Hyperten | 1982 |
The effect of metoprolol --a new selective adrenergic beta1-receptor blocking agent-- in mild hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Depr | 1976 |
Hemodynamic effects of adrenergic beta-receptor blocking agents.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Cardiac Output; Clinical Trials as Topic; Double-Bli | 1976 |
[Preventive effects of beta-blockers on myocardial infarction and on cardiac accidents following a first infarct].
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Humans; Hy | 1978 |
Clinical pharmacology of adrenergic-blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Blood Pressure; Clinical Trials as | 1979 |
[Treatment of hypertension with alprenolol (Corbetan)].
Topics: Alprenolol; Clinical Trials as Topic; Female; Humans; Hypertension; Male | 1977 |
Influence of alprenolol on hemodynamic and metabolic responses to prolonged exercise in subjects with hypertension.
Topics: Alprenolol; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Drug Evaluation; Heart Rate; H | 1977 |
[Antihypertensive therapy with a new beta-blocking agent Timolol. Double blind study and comparison with Alprenolol and Pindolol (author's transl)].
Topics: Adult; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male | 1977 |
Long-term clinical experience with atenolol--a new selective beta-1-blocker with few side-effects from the central nervous system.
Topics: Adult; Aged; Alprenolol; Atenolol; Central Nervous System; Clinical Trials as Topic; Drug Evaluation | 1979 |
A comparison between metroprolol, alprenolol and oxprenolol in the treatment of hypertension.
Topics: Alprenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Ev | 1979 |
Double-blind comparison of metoprolol, alprenolol, and oxprenolol in hypertension.
Topics: Adult; Aged; Alprenolol; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 1979 |
Placebo-controlled, double-blind clinical trial of alprenolol in African hypertensive patients.
Topics: Adult; Alprenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hy | 1979 |
Hydralazine slow-release: observations on serum profile and clinical efficacy in man.
Topics: Adult; Alprenolol; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Hydralazin | 1977 |
[Long-term treatment of essential hypertension with hydralazine and alprenolol].
Topics: Alprenolol; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; M | 1978 |
Twice-daily pindolol and alprenolol in essential hypertension of moderate severity.
Topics: Administration, Oral; Adult; Alprenolol; Blood Pressure; Clinical Trials as Topic; Dose-Response Rel | 1976 |
Metoprolol in the long-term treatment of hypertension.
Topics: Adult; Aged; Alprenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; | 1976 |
Effect of long-term anti-hypertensive beta-receptor-blocking treatment on haemodynamic and metabolic responses to prolonged exercise in man.
Topics: Adult; Alprenolol; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Humans; Hypertension; Lactates; | 1976 |
Angina pectoris, hypertension, decompensation and return to work during two years' follow-up.
Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Disability Evaluation; | 1975 |
Predictive value of sympathetic cardiovascular reflexes and urinary catecholamines when selecting patients for antihypertensive treatment with beta-adrenergic blocking drugs.
Topics: Adult; Alprenolol; Catecholamines; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertensio | 1975 |
Effect of beta adrenergic blocking agents (alprenolol and propranolol) in essential hypertension.
Topics: Adult; Alprenolol; Antihypertensive Agents; Drug Evaluation; Female; Heart Rate; Humans; Hypertensio | 1975 |
[Treatment of arterial hypertension using beta-blockaders].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Drug Evaluation; Humans; Hyperten | 1974 |
Comparison between alprenolol and chlorthalidone as antihypertensive agents.
Topics: Adult; Alprenolol; Amino Alcohols; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials as T | 1972 |
Comparison between alprenolol and propranolol as antihypertensive agents. A double-blind cross-over study.
Topics: Adult; Alprenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; Humans | 1972 |
Effect of alprenolol on blood pressure and plasma renin activity in hypertensive patients.
Topics: Adult; Aged; Alprenolol; Blood Pressure; Blood Volume; Chlorthalidone; Clinical Trials as Topic; Dru | 1973 |
[Combination therapy with alprenolol and hydralazine in essential hypertension. A controlled clinical study].
Topics: Adult; Alprenolol; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Drug Therapy, Com | 1973 |
Comparative study of alprenolol and methyldopa in previously untreated essential hypertension.
Topics: Adult; Age Factors; Alprenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; H | 1973 |
A long-term study of the antihypertensive effect of alprenolol.
Topics: Adult; Aged; Alprenolol; Blood Pressure Determination; Chlorthalidone; Clinical Trials as Topic; Del | 1974 |
The effect of alprenolol in elderly patients with raised blood pressure.
Topics: Aged; Alprenolol; Ambulatory Care; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparat | 1974 |
Effect of alprenolol and alprenolol in combination with saluretics in hypertension.
Topics: Adult; Aged; Alprenolol; Benzothiadiazines; Blood Pressure; Body Weight; Clinical Trials as Topic; D | 1974 |
Alprenolol and propranolol in the treatment of hypertension: a comparative study.
Topics: Adult; Alprenolol; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Diuretics; Drug E | 1974 |
A comparative study of alprenolol and alpha-methyldopa respectively in combination with chlorthalidone in hypertension.
Topics: Adult; Aged; Alprenolol; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Delayed-Action Pr | 1974 |
The effect of alprenolol in combination with hydralazine in essential hypertension. A double-blind, crossover study and a long-term follow-up study.
Topics: Adult; Alprenolol; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Delayed-A | 1974 |
Alprenolol in hypertension.
Topics: Aged; Alprenolol; Benzothiadiazines; Chlorthalidone; Clinical Trials as Topic; Digitalis; Diuretics; | 1974 |
Long-term effect of alprenolol as antihypertensive agent.
Topics: Adult; Airway Obstruction; Alprenolol; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials | 1974 |
[Alprenolol and alphamethyl-dopa in untreated cases of essential hypertension--a comparison].
Topics: Adult; Alprenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Drug Evaluatio | 1973 |
A within-patient comparison of alprenolol and propranolol in hypertension.
Topics: Adult; Alprenolol; Blood Pressure; Depression, Chemical; Female; Heart Rate; Humans; Hypertension; M | 1973 |
62 other studies available for alprenolol and Hypertension
| Article | Year |
|---|---|
[Changes in the density of human lymphocyte beta-adrenergic receptors in hypertension].
Topics: Adult; Alprenolol; Dihydroalprenolol; Humans; Hypertension; Lymphocytes; Male; Phentolamine; Radioli | 1984 |
Detection of some antihypertensive drugs and their metabolites in urine by thin-layer chromatography: II. A further five beta blockers and dihydralazine.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Chromatography, Thin Layer; Dihydralazine; Humans | 1980 |
Renal effects of beta-adrenoceptor blockade.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Blood Pressure; Cardia | 1980 |
Variability in the preventive action of the B-blockers on genetic hypertension in the rat.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relation | 1980 |
Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Hemodynamics; Humans; Hypertension; Metoprolol; P | 1983 |
BAAM: a better beta-blocker--and more?
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Cyclohexane Monoterpenes; Drug Evaluation; | 1984 |
[Characteristics of 3H-dihydroalprenolol binding to beta-receptors in the fat cells of rats and spontaneous genetic hypertension and in hypertensive disease].
Topics: Adipose Tissue; Adrenalectomy; Alprenolol; Animals; Binding Sites; Cell Membrane; Dihydroalprenolol; | 1980 |
Results of treatment of hypertension after renal transplantation: effects of converting enzyme inhibitor, angiotensin II analog, beta-blockade, and dopamine beta-hydroxylase inhibitor.
Topics: Adolescent; Adult; Alprenolol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Press | 1980 |
Binding of 3H-dihydroalprenolol to beta-adrenoceptors in adipocytes of spontaneously hypertensive rats and essentially hypertensive patients.
Topics: Adipose Tissue; Adult; Alprenolol; Animals; Cell Membrane; Dihydroalprenolol; Female; Humans; Hypert | 1982 |
Prazosin first dose phenomenon during combined treatment with a beta-adrenoceptor blocker in hypertensive patients.
Topics: Adult; Alprenolol; Blood Pressure; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; | 1982 |
[Effect of beta-adrenergic blocking agent (alprenolol) (author's transl)].
Topics: Aged; Alprenolol; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Female; | 1982 |
Changes in catecholamine neuronal uptake and receptor binding in the brains of spontaneously hypertensive rats (SHR).
Topics: Aging; Alprenolol; Animals; Biological Transport; Brain; Dihydroalprenolol; Dopamine; Hypertension; | 1981 |
Alprenolol-induced thrombocytopenia.
Topics: Aged; Alprenolol; Female; Humans; Hypertension; Platelet Count; Prednisolone; Thrombocytopenia | 1980 |
Loss of maximum attenuation and receptor reserve for isoprenaline at the beta 2-adrenoceptors of the portal veins of hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Hypertension; Hypertroph | 1995 |
The effects of bromoacetylalprenololmenthane on the responses to isoprenaline of the left ventricle from normo-, prehyper- and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Res | 1997 |
Affinity constants and beta-adrenoceptor reserves for isoprenaline on cardiac tissue from normotensive and hypertensive rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Female; Heart; Heart Atr | 1998 |
One doctor's 25-year experience of beta-blocker treatment to the same group of hypertensive women.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Antihypertensive Agents; Body Weight; Continuity of | 1999 |
Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats.
Topics: Adrenergic beta-Agonists; Algorithms; Alprenolol; Animals; Aorta, Thoracic; Binding, Competitive; Bl | 2002 |
[Therapy of hypertension using various beta receptor blockaders (timolol, alprenolol, prindolol].
Topics: Adrenergic beta-Antagonists; Alprenolol; Antihypertensive Agents; Humans; Hypertension; Pindolol | 1975 |
Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. I. Relationship between plasma concentration and adrenergic beta-receptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Dose-Response Relationship, Drug; Female; Heart Rate | 1976 |
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metopro | 1976 |
[Indications and limits for the use of beta-blockaders (beta-adrenergic inhibitors) in the treatment of hypertension].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Humans; Hypertension; Propranol | 1977 |
Peripheral haemodynamics in essential hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Huma | 1977 |
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects.
Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; | 1978 |
Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Circulation; Cardiac Output; Female; Humans; Hyperten | 1979 |
[Effect of dl-propranolol and l-and d-alprenolol on arterial pressure in awake or anesthesized, normo- or hypertensive rats].
Topics: Alprenolol; Animals; Blood Pressure; Chloralose; Hypertension; Pentobarbital; Propranolol; Rats; Ste | 1975 |
Reduced number of beta-adrenergic receptors in the myocardium of spontaneously hypertensive rats.
Topics: Alprenolol; Animals; Blood Pressure; Hypertension; Kinetics; Male; Myocardium; Rats; Receptors, Adre | 1978 |
Decreased number of beta-adrenergic receptors in hypertensive vessels.
Topics: Alprenolol; Animals; Binding Sites; Binding, Competitive; Blood Vessels; Cell Membrane; Hypertension | 1979 |
[Antihypertensive therapy using beta receptor blockers].
Topics: Adrenergic beta-Antagonists; Alprenolol; Cardiac Output; Heart Rate; Humans; Hypertension; Hypertens | 1975 |
Metabolic changes in muscle on long-term alprenolol therapy.
Topics: Adenosine Triphosphate; Adult; Alprenolol; Blood Pressure; Glucose; Glycogen; Heart Rate; Humans; Hy | 1979 |
Acute cardiovascular activity of beta-adrenoceptor blocking drugs in awake or anaesthetized normotensive and hypertensive rats.
Topics: Alprenolol; Anesthesia; Animals; Blood Pressure; Hemodynamics; Hypertension; Kinetics; Male; Propran | 1977 |
Carotid baroreceptor function in hypertensive patients.
Topics: Adult; Alprenolol; Blood Pressure; Cardiac Output; Carotid Sinus; Female; Heart Rate; Humans; Hypert | 1977 |
[Hypotensive effect of alpheprol].
Topics: Alprenolol; Humans; Hypertension; Male; Middle Aged | 1978 |
[Thrombocytopenia caused by alprenolol].
Topics: Adult; Alprenolol; Female; Humans; Hypertension; Thrombocytopenia | 1979 |
Haemodynamic effects of saluretic treatment and beta-receptor blockade in patients with essential hypertension.
Topics: Adult; Alprenolol; Blood Pressure; Cardiac Output; Diuretics; Drug Therapy, Combination; Female; Fol | 1977 |
Monoamine metabolites in cerebrospinal fluid during treatment with clonidine or alprenolol.
Topics: Adult; Alprenolol; Biogenic Amines; Blood Pressure; Clonidine; Dopamine; Female; Humans; Hypertensio | 1977 |
Plasma renin concentration in essential hypertension during beta-adrenergic blockade and vasodilator therapy.
Topics: Adult; Alprenolol; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertens | 1977 |
Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate, and renal plasma flow in patients with essential hypertension.
Topics: Aged; Albuminuria; Alprenolol; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Guinea P | 1976 |
Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. II. Relationship to its effect on blood pressure and plasma renin activity.
Topics: Adult; Alprenolol; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hyp | 1976 |
Relationship between plasma aldosterone concentration and plasma potassium in patients with essential hypertension during alprenolol treatment.
Topics: Adult; Aldosterone; Alprenolol; Blood Pressure; Female; Humans; Hypertension; Male; Potassium; Renin | 1976 |
[Treatment of hypertension with beta blocking agents].
Topics: Alprenolol; Drug Therapy, Combination; Humans; Hypertension; Oxprenolol; Pindolol; Propranolol | 1975 |
Glomerular filtration rate and renal plasma flow in patients with essential hypertension before and after treatment with alprenolol.
Topics: Adult; Aged; Alprenolol; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hyp | 1975 |
Effect of alprenolol and hydralazine on plasma renin concentration in patients with arterial hypertension.
Topics: Adult; Aged; Alprenolol; Depression, Chemical; Drug Therapy, Combination; Female; Humans; Hydralazin | 1975 |
Catecholamines in plasma and urine in patients with essential hypertension determined by double-isotope derivative techniques.
Topics: Adult; Age Factors; Aged; Alprenolol; Dopamine; Drug Therapy, Combination; Epinephrine; Female; Huma | 1975 |
[Use of aptine in treatment of arterial hypertension].
Topics: Adult; Aged; Alprenolol; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged | 1975 |
Continuous alprenolol infusion for control of hypertension in the acute stage of ruptured intracranial aneurysms.
Topics: Adult; Aged; Alprenolol; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Intracranial An | 1991 |
[Synthesis of new beta-blockaders analogs of bevantolol or alprenolol].
Topics: Adrenergic beta-Antagonists; Alprenolol; Chemical Phenomena; Chemistry; Hypertension; Propanolamines | 1987 |
[Interindividual changes in the specific binding of 3H-dihydroalprenolol by beta 2-adrenergic lymphocytic receptors in essential hypertension].
Topics: Adult; Alprenolol; Dihydroalprenolol; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Recept | 1986 |
Decreased plasma concentrations and clinical effects of alprenolol during combined treatment with pentobarbitone in hypertension.
Topics: Adult; Alprenolol; Blood Pressure; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hyp | 1987 |
[Current drugs. Therapy using -blockaders ( -adrenolytics)].
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Angina Pectoris; Arrhythmias, | 1973 |
[Beta-blockaders in hypertension].
Topics: Adrenergic beta-Antagonists; Alprenolol; Drug Therapy, Combination; Humans; Hydralazine; Hypertensio | 1973 |
[Letter: Beta blockaders yet again].
Topics: Adrenergic beta-Antagonists; Alprenolol; Humans; Hypertension; Propranolol | 1973 |
Editorial: The pharmacology and therapeutic use of beta-adrenergic receptor blocking drugs in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Arrhythmias, Cardiac; Cardiovascular Disea | 1974 |
Beta-blockade for hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Antihypertensive Agents; Humans; Hypertension; Oxprenolol; | 1974 |
Chronic beta adrenergic blockade in arterial hypertension. Hemodynamic influences of dihydralazine and dynamic exercise and clinical effects of combined treatment.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Alprenolol; Amino Alcohols; Blood Pressure | 1972 |
Antihypertensive activity of four blocking agents in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Blood Pressure; Clonidine | 1972 |
[What is assured in treatment with beta receptor blockaders?].
Topics: Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Cresols; Heart Diseases; Huma | 1972 |
Steady-state plasma concentrations of alprenolol in man.
Topics: Alprenolol; Angina Pectoris; Chromatography, Gas; Dose-Response Relationship, Drug; Half-Life; Human | 1974 |
[Our experiences with Aptin therapy of hypertension].
Topics: Alprenolol; Humans; Hypertension | 1973 |
[A beta blocking agent as an antihypertensive agent].
Topics: Aged; Alprenolol; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Practo | 1973 |
Cardiovascular responses to acute mental 'stress' in spontaneously hypertensive rats.
Topics: Alprenolol; Animals; Atropine; Blood Pressure; Depression, Chemical; Epinephrine; Female; Heart Rate | 1974 |
Hemodynamic interference of alprenolol with dihydralazine in normal and hypertensive man.
Topics: Adult; Alprenolol; Cardiac Output; Cardiac Volume; Drug Interactions; Female; Heart Rate; Hemodynami | 1971 |