Page last updated: 2024-08-23

colforsin and Hypertension

colforsin has been researched along with Hypertension in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.75)	18.7374
1990's	34 (55.74)	18.2507
2000's	14 (22.95)	29.6817
2010's	4 (6.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Houser, SR; Kendrick, ZV; Kolwicz, SC; Libonati, JR; MacDonnell, SM	1
Bian, JS; Goh, HS; Liu, YH; Lu, M; Wang, JJ; Wang, R; Yong, QC	1
Anand-Srivastava, MB; Li, Y; Sandoval, YH	1
Calderon, L; Guo, Z; Liu, D; Liu, S; Turk, J; Xie, Z; Zhao, G	1
Chang, L; Chu, W; He, K; Li, X; Lu, Y; Mu, X; Qiao, G; Sun, H; Zhou, X	1
Barthel, A; Bornstein, SR; Ehrhart-Bornstein, M; Hauner, H; Lamounier-Zepter, V; Langenbach, J; McCann, SM; Scherbaum, WA; Schraven, A; Willenberg, HS	1
Anand-Srivastava, MB; Hashim, S	1
Abderrahim, F; Arribas, SM; Conde, MV; Díaz-Gil, JJ; Fernández-Alfonso, MS; González, JM; González, MC; Regadera, J; Somoza, B; Starcher, B	1
Andrews, J; Chorazyczewski, J; Ding, Q; Feldman, RD; Gros, R; Hegele, RA; Pickering, JG	1
Anand-Srivastava, MB; Daou, GB; Lappas, G	1
Houser, SR; Kolwicz, SC; Kubo, H; Libonati, JR; MacDonnell, SM	1
Anand-Srivastava, MB; Li, Y; Saha, S	1
Dean, T; Kornhauser, R	1
Blankesteijn, WM; de Pont, JJ; Graafsma, SJ; Thien, T; Willems, PH	1
Atkins, FL; Bing, OH; Brooks, WW; Conrad, CH; DiMauro, PG; Robinson, KG	1
Caflisch, CR; George, T; Good, DW	1
Bogoyevitch, MA; Fuller, SJ; Sugden, PH	1
Felder, RA; Kaskel, FJ; Kinoshita, S; Ohbu, K	1
Ganten, D; Kreutz, R; Pfitzer, G; Satoh, S; Wilm, C	1
Baba, A; Fukuda, K; Kasamatsu, K; Masuyama, Y; Nishio, I; Wanaka, Y; Yoshikawa, H	1
Gao, Y; Nishimura, Y; Suzuki, A; Yoshida, K	1
Felder, RA; Hendley, ED; Ohbu, K; Yamaguchi, I	1
Contney, SJ; Rusch, NJ; Stekiel, WJ	1
Faraci, FM; Heistad, DD; Kitazono, T	1
Böhm, M; Erdmann, E; Gierschik, P; Knorr, A; Schmidt, U; Weismann, K	1
Clark, CJ; Connell, JM; Milligan, G	1
Canessa, LM; Felder, RA; Jose, PA; Kinoshita, S; Minowa, MT; Minowa, T; Monsma, FJ; Mouradian, MM; Ohbu, K; Sibley, DR	1
Anand-Srivastava, MB; Marcil, J; Schiffrin, EL	1
Chorazyczewski, J; Feldman, RD	1
Batink, HD; Beenen, OH; Pfaffendorf, M; van Zwieten, PA	1
Anand-Srivastava, MB; Marcil, J; Thibault, C	1
Bond, M; McConnell, BK; Morano, I; Moravec, CS	1
Imaizumi, T; Kaku, H; Koga, Y; Muro, A; Nohara, M; Sumida, E; Toshima, H	1
Clemow, DB; McCarty, R; Steers, WD; Tuttle, JB	1
Fukuzawa, J; Haneda, T; Kashiwagi, Y; Kikuchi, K; Oi, S; Osaki, J; Sakai, H	1
Anand-Srivastava, MB; de Champlain, J; Marcil, J	1
Borea, PA; Caiazza, A; Gessi, S; Portaluppi, F; Rastelli, G; Varani, K	1
Wang, HX; Wong, TM; Yu, XC; Zhang, WM	1
Carroll, JF	1
Brown, L; Lau, K; Ooi, SY; Sernia, C	1
Sekiguchi, F; Shimamura, K; Sunano, S; Yamamoto, K	1
Kosaka, H; Yoneyama, H; Zhou, MS	1
Abe, I; Fujii, K; Goto, K	1
Becker, M; Beheray, S; Hussain, T; Lokhandwala, MF	1
Chen, YY; Doggrell, SA	1
Kajimoto, N; Nishimura, Y; Suzuki, A; Usui, H; Yamanishi, Y	1
Aripova, NA; Krasnikova, TL; Parfyonova, EV; Yurenev, AP	1
Mathy, MJ; Mertens, MJ; Pfaffendorf, M; van Zwieten, PA	1
Macrae, IM; McAuley, MA; Reid, JL	1
Printseva, OY; Tjurmin, AV	1
Baba, A; Fukuda, K; Kuchii, M; Masuyama, Y; Nishio, H; Nishio, I; Ueyama, T; Yoshikawa, A; Yoshikawa, H	1
Fukuda, N; Hatano, M; Honda, M; Izumi, Y; Minato, M; Soma, M	1
Asano, M; Masuzawa, K; Matsuda, T	2
Asano, M; Asano, T; Masuzawa, K; Matsuda, T	1
Kamibayashi, C; Ramanathan, S	1
Distler, A; Fritschka, E; Pauliks, LB; Philipp, T; Schultz, KD	1
Brunelle, G; Coquil, JF; Meyer, P	1
Kocmund, SM; Michalak, RJ; Silver, PJ	1
Katada, T; Murakami, T; Yasuda, H	1
Anand-Srivastava, MB	1

Trials

1 trial(s) available for colforsin and Hypertension

Article	Year
Platelet alpha2-adrenoceptor alterations in patients with essential hypertension. British journal of clinical pharmacology, 1999, Volume: 47, Issue:2 Topics: Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Colforsin; Cyclic AMP; Epinephrine; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Male; Middle Aged; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Thermodynamics	1999

Article

Year

Platelet alpha2-adrenoceptor alterations in patients with essential hypertension.

British journal of clinical pharmacology, 1999, Volume: 47, Issue:2

Topics: Adrenergic alpha-Antagonists; Blood Platelets; Brimonidine Tartrate; Colforsin; Cyclic AMP; Epinephrine; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Male; Middle Aged; Protein Binding; Quinoxalines; Receptors, Adrenergic, alpha-2; Thermodynamics

1999

Other Studies

60 other study(ies) available for colforsin and Hypertension

Article	Year
Voluntary wheel running and pacing-induced dysfunction in hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 2008, Volume: 30, Issue:7 Topics: Adenylyl Cyclases; Animals; Blood Pressure; Cardiac Pacing, Artificial; Colforsin; Female; Heart Rate; Hypertension; In Vitro Techniques; Physical Exertion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Ventricular Dysfunction, Left	2008
Hydrogen sulfide inhibits plasma renin activity. Journal of the American Society of Nephrology : JASN, 2010, Volume: 21, Issue:6 Topics: Adenylyl Cyclases; Animals; Blood Pressure; Cells, Cultured; Colforsin; Cyclic AMP; Disease Models, Animal; Hydrogen Sulfide; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sulfides	2010
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR. Cellular signalling, 2011, Volume: 23, Issue:11 Topics: Acetylcysteine; Adenylyl Cyclases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Colforsin; CSK Tyrosine-Protein Kinase; ErbB Receptors; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; src-Family Kinases; Transcriptional Activation	2011
Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth muscles. The Journal of biological chemistry, 2011, Dec-30, Volume: 286, Issue:52 Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Nucleus; Cells, Cultured; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Group VI Phospholipases A2; GTP-Binding Protein Regulators; Humans; Hypertension; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Polymorphism, Single Nucleotide; Protein Kinase C; Rabbits; Rats; Response Elements; RGS Proteins; Transcription, Genetic; Up-Regulation; Vasoconstrictor Agents	2011
Hydrogen peroxide induces overexpression of angiotensin-converting enzyme in human umbilical vein endothelial cells. Free radical research, 2013, Volume: 47, Issue:2 Topics: Apoptosis; Cell Line; Cell Survival; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; In Situ Nick-End Labeling; Oligodeoxyribonucleotides; Oxidative Stress; Peptidyl-Dipeptidase A; RNA, Messenger; Signal Transduction; Transcriptional Activation	2013
Human adipocytes secrete mineralocorticoid-releasing factors. Proceedings of the National Academy of Sciences of the United States of America, 2003, Nov-25, Volume: 100, Issue:24 Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Base Sequence; Colforsin; Culture Media, Conditioned; Female; Hot Temperature; Humans; Hypertension; In Vitro Techniques; Mineralocorticoids; Models, Biological; Obesity; Phosphoproteins; RNA, Messenger	2003
Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. Journal of hypertension, 2004, Volume: 22, Issue:1 Topics: Adenylyl Cyclases; Animals; Antihypertensive Agents; Blood Pressure; Colforsin; Disease Models, Animal; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Losartan; Male; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger; Sodium Fluoride; Statistics as Topic	2004
Short-term treatment of spontaneously hypertensive rats with liver growth factor reduces carotid artery fibrosis, improves vascular function, and lowers blood pressure. Cardiovascular research, 2006, Feb-15, Volume: 69, Issue:3 Topics: Acetylcholine; Animals; Bilirubin; Carotid Arteries; Cell Count; Colforsin; Collagen; Desmosine; Dose-Response Relationship, Drug; Elastin; Fibrosis; Hypertension; In Vitro Techniques; Isometric Contraction; Male; Microscopy, Confocal; Mitogens; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serum Albumin; Serum Albumin, Human; Time Factors; Vasodilator Agents	2006
The impact of blunted beta-adrenergic responsiveness on growth regulatory pathways in hypertension. Molecular pharmacology, 2006, Volume: 69, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Base Sequence; Cell Proliferation; Cells, Cultured; Colforsin; DNA Primers; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hypertension; Isoproterenol; Male; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta	2006
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of hypertension, 2005, Volume: 23, Issue:12 Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Onium Compounds; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Superoxides	2005
Effects of forskolin on inotropic performance and phospholamban phosphorylation in exercise-trained hypertensive myocardium. Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:2 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood Pressure; Calcium-Binding Proteins; Colforsin; Cyclic AMP; Female; Heart Rate; Hypertension; Isoproterenol; Myocardial Contraction; Myocardium; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Inbred WKY; Receptors, Adrenergic, beta; Ventricular Function, Left	2007
Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats. Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:4 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Activators; Hypertension; Isoproterenol; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides	2008
Increased platelet reactivity to prostaglandin E1 in hypertension is linked with altered signal transduction. American journal of hypertension, 1993, Volume: 6, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Blood Platelets; Colforsin; Cyclic AMP; GTP Phosphohydrolases; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction	1993
Forskolin-stimulated adenylyl cyclase activity is decreased but beta 2-adrenoceptor function is unchanged in primary hypertension. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5 Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Adult; Binding, Competitive; Cell Membrane; Colforsin; Female; Hemodynamics; Humans; Hypertension; Isoproterenol; Leukocytes, Mononuclear; Male; Middle Aged; Pindolol; Receptors, Adrenergic, beta; Sex Factors	1993
Modulation of left and right ventricular beta-adrenergic receptors from spontaneously hypertensive rats with left ventricular hypertrophy and failure. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:1 Topics: Animals; Biochemical Phenomena; Biochemistry; Colforsin; Heart Failure; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Stimulation, Chemical	1995
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR. The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 2 Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera Toxin; Colforsin; Dinoprostone; Hypertension; Ions; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate	1995
cAMP and protein synthesis in isolated adult rat heart preparations. The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1 Topics: 1-Methyl-3-isobutylxanthine; Adenine Nucleotides; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Energy Metabolism; Epinephrine; Glucagon; Heart; Hypertension; In Vitro Techniques; Isoproterenol; Kinetics; Male; Myocardium; Perfusion; Phenylephrine; Phosphocreatine; Prazosin; Propranolol; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Yohimbine	1993
Dopamine-1 receptors in the proximal convoluted tubule of Dahl rats: defective coupling to adenylate cyclase. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Adenylyl Cyclases; Animals; Benzothiazoles; Blood Pressure; Colforsin; Cyclic AMP; Dopamine Agonists; Female; Fenoldopam; Hypertension; Kidney Tubules, Proximal; Male; Pramipexole; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Sodium, Dietary; Thiazoles	1995
Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells. The Journal of clinical investigation, 1994, Volume: 94, Issue:4 Topics: Actin Cytoskeleton; Animals; Calcium; Cell Membrane Permeability; Colforsin; Coronary Vessels; Escin; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Signal Transduction	1994
Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension. American journal of hypertension, 1994, Volume: 7, Issue:8 Topics: Adenylyl Cyclases; Adult; Blood Pressure; Case-Control Studies; Cholera Toxin; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Heart Rate; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Middle Aged; Radioligand Assay; Receptors, Adrenergic, beta	1994
Relaxant effects of calcitonin gene-related peptide on isolated small renal arteries in stroke-prone spontaneously hypertensive rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1994, Volume: 30, Issue:1 Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Colforsin; Dose-Response Relationship, Drug; Glyburide; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery	1994
Renal dopamine-1 receptors in hypertensive inbred rat strains with and without hyperactivity. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:4 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Aging; Animals; Benzazepines; Blood Pressure; Colforsin; Dopamine Agents; Fenoldopam; Guanylyl Imidodiphosphate; Hypertension; Iodine Radioisotopes; Kidney; Kidney Cortex; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Kinetics; Male; Motor Activity; Nephrons; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Dopamine D1; Sodium	1993
Altered beta-receptor control of in situ membrane potential in hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:6 Pt 2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cholera Toxin; Colforsin; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta	1993
ATP-sensitive potassium channels in the basilar artery during chronic hypertension. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5 Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Basilar Artery; Cerebrovascular Disorders; Colforsin; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Picolines; Potassium Channels; Pyrans; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation	1993
Cardiac adenylyl cyclase, beta-adrenergic receptors, and G proteins in salt-sensitive hypertension. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5 Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Amino Acid Sequence; Animals; Blood Pressure; Cardiomegaly; Cell Membrane; Colforsin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Hypertension; Immune Sera; Kinetics; Lymphoma; Male; Mice; Molecular Sequence Data; Myocardium; NAD; Oligopeptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Recombinant Proteins; Sodium Chloride; Transducin; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella	1993
Guanine nucleotide regulatory protein alterations in young Milan hypertensive strain rats. Biochimica et biophysica acta, 1994, Jan-11, Volume: 1225, Issue:2 Topics: Adenylyl Cyclases; Alprostadil; Amino Acid Sequence; Animals; Cell Membrane; Cells, Cultured; Colforsin; GTP-Binding Proteins; Hypertension; Immune Sera; Isoproterenol; Molecular Sequence Data; Muscle, Smooth, Vascular; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Signal Transduction	1994
Organ specificity of the dopamine1 receptor/adenylyl cyclase coupling defect in spontaneously hypertensive rats. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2 Topics: Adenylyl Cyclases; Animals; Autoradiography; Colforsin; Corpus Striatum; Hypertension; Kidney Tubules, Proximal; Male; Organ Specificity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine; RNA, Messenger	1993
Aberrant adenylyl cyclase/cAMP signal transduction and G protein levels in platelets from hypertensive patients improve with antihypertensive drug therapy. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:1 Topics: Adenylyl Cyclases; Adult; Antihypertensive Agents; Blood Platelets; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Humans; Hypertension; Immunoblotting; Male; Middle Aged; Signal Transduction	1996
G-protein function is reduced in hypertension. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Age Factors; Colforsin; GTP-Binding Proteins; Humans; Hypertension; Lymphocytes; Middle Aged	1997
Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments. Blood pressure, 1997, Volume: 6, Issue:1 Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiotonic Agents; Colforsin; Diabetes Mellitus, Experimental; Dobutamine; Heart; Heart Rate; Hypertension; Myocardial Contraction; Myocardium; Organ Size; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta	1997
Enhanced expression of Gi-protein precedes the development of blood pressure in spontaneously hypertensive rats. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:3 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Age Factors; Animals; Animals, Newborn; Aorta; Atrial Natriuretic Factor; Blood Pressure; Colforsin; Enzyme Inhibitors; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Hormones; Hypertension; Muscarinic Agonists; Myocardium; Oxotremorine; Rats; Rats, Inbred SHR; RNA, Messenger	1997
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Heart; Heart Ventricles; Hypertension; Isoproterenol; Marine Toxins; Myocardial Contraction; Myocardium; Myosin Light Chains; Norepinephrine; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Troponin I	1997
Altered calcium handling in compensated hypertrophied rat cardiomyocytes induced by pressure overload. Japanese circulation journal, 1998, Volume: 62, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiomegaly; Cells, Cultured; Colforsin; Heart; Hemodynamics; Homeostasis; Hypertension; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Rats; Rats, Wistar	1998
Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: Animals; Cells, Cultured; Colforsin; Hypertension; Isoproterenol; Nerve Growth Factors; Neuronal Plasticity; Neuropeptide Y; Phenylephrine; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Tetradecanoylphorbol Acetate; Urinary Bladder; Urination; Urination Disorders	1998
Pressure-induced expression of heat shock protein 70 mRNA in adult rat heart is coupled both to protein kinase A-dependent and protein kinase C-dependent systems. Journal of hypertension, 1998, Volume: 16, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Pressure; Cardiomegaly; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucagon; HSP70 Heat-Shock Proteins; Hypertension; In Vitro Techniques; Isoquinolines; Male; Myocardium; Naphthalenes; Perfusion; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides	1998
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase. Cardiovascular research, 1998, Volume: 39, Issue:2 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors	1998
Cross-talk between cardiac kappa-opioid and beta-adrenergic receptors in developing hypertensive rats. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic alpha-Agonists; Age Factors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium; Captopril; Colforsin; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Hypertension; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Opioid, kappa; Systole	1999
Post-beta-receptor defect in isolated hearts of obese-hypertensive rabbits. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1999, Volume: 23, Issue:8 Topics: Analysis of Variance; Animals; Blood Pressure; Cardiotonic Agents; Colforsin; Disease Models, Animal; Female; Heart; Heart Rate; Hypertension; Myocardial Contraction; Obesity; Rabbits; Random Allocation; Receptors, Adrenergic, beta; Signal Transduction	1999
Cardiac and vascular responses in deoxycorticosterone acetate-salt hypertensive rats. Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:4 Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium Chloride; Carbachol; Colforsin; Desoxycorticosterone; Dose-Response Relationship, Drug; Heart; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Myocardial Contraction; Nephrectomy; Norepinephrine; Papillary Muscles; Potassium Chloride; Rats; Rats, Wistar; Sodium Chloride; Systole; Theophylline; Time Factors; Vasoconstrictor Agents; Vasodilator Agents	2000
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2000, Volume: 36, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; Gastric Emptying; Gastric Fundus; Gastric Mucosa; Hypertension; Isoproterenol; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta	2000
Potassium augments vascular relaxation mediated by nitric oxide in the carotid arteries of hypertensive Dahl rats. American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1 Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Carotid Arteries; Colforsin; Dietary Supplements; Enzyme Inhibitors; Hypertension; Isoproterenol; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Nitroprusside; Penicillamine; Potassium, Dietary; Rats; Rats, Inbred Dahl; S-Nitroso-N-Acetylpenicillamine; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasodilation; Vasodilator Agents	2000
Impaired beta-adrenergic hyperpolarization in arteries from prehypertensive spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Animals; Antihypertensive Agents; Cholera Toxin; Colforsin; Cromakalim; Hypertension; Isoproterenol; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vascular Resistance	2001
Dopamine fails to inhibit Na,H-exchanger in proximal tubules of obese Zucker rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2001, Volume: 23, Issue:8 Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Hypertension; In Vitro Techniques; Kidney Tubules, Proximal; Male; Microvilli; Obesity; Rats; Rats, Zucker; Receptors, Dopamine D1; Signal Transduction; Sodium-Hydrogen Exchangers	2001
Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats. The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4 Topics: Adrenergic beta-Agonists; Algorithms; Alprenolol; Animals; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Colforsin; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Vasoconstriction	2002
Relaxant response of isolated basilar arteries to calcitonin gene-related peptide in stroke-prone spontaneously hypertensive rats. Japanese journal of pharmacology, 1992, Volume: 59, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Bucladesine; Calcitonin Gene-Related Peptide; Colforsin; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation	1992
Alteration of beta-adrenoceptor function in hypertensive patients with different degrees of left ventricular hypertrophy. American journal of hypertension, 1992, Volume: 5, Issue:6 Pt 2 Topics: Adult; Blood Pressure; Cardiomegaly; Colforsin; Humans; Hypertension; Isoproterenol; Lymphocytes; Male; Receptors, Adrenergic, beta	1992
Depressed inotropic response to beta-adrenoceptor agonists in the presence of advanced cardiac hypertrophy in hearts from rats with induced aortic stenosis and from spontaneously hypertensive rats. Journal of hypertension, 1992, Volume: 10, Issue:11 Topics: Adrenergic beta-Agonists; Animals; Aortic Diseases; Bucladesine; Cardiomegaly; Colforsin; Constriction; Depression, Chemical; Hypertension; Male; Myocardial Contraction; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1992
Central cardiovascular effects of rilmenidine and neuropeptide Y in the conscious spontaneously hypertensive rat: haemodynamic and biochemical evidence for a negative interaction. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:6 Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; In Vitro Techniques; Male; Medulla Oblongata; Neuropeptide Y; Oxazoles; Rats; Rats, Inbred SHR; Rilmenidine	1992
Proliferative response of smooth muscle cells in hypertension. American journal of hypertension, 1992, Volume: 5, Issue:6 Pt 2 Topics: Adult; Aged; Animals; Autoradiography; Cell Count; Cell Division; Cells, Cultured; Colforsin; DNA; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Hypertension; Male; Mathematics; Middle Aged; Muscle, Smooth; Norepinephrine; Ploidies; Rats; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thymidine; Tritium	1992
Deficient activity of nucleotide binding regulatory protein coupled with PGE2 receptor in renal medulla of spontaneously hypertensive rats. American journal of hypertension, 1990, Volume: 3, Issue:3 Topics: Adenylyl Cyclases; Animals; Colforsin; Dinoprostone; GTP-Binding Proteins; Hypertension; Kidney Medulla; Male; Prostaglandins E; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin; Sodium Fluoride	1990
Adenylate cyclase activities of vascular smooth muscle in early and established DOCA/salt hypertensive rats. Japanese circulation journal, 1990, Volume: 54, Issue:1 Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calmodulin; Colforsin; Desoxycorticosterone; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic	1990
Evidence for reduced beta-adrenoceptor coupling to adenylate cyclase in femoral arteries from spontaneously hypertensive rats. British journal of pharmacology, 1988, Volume: 94, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Femoral Artery; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta	1988
Reduced function of the stimulatory GTP-binding protein in beta adrenoceptor-adenylate cyclase system of femoral arteries isolated from spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Femoral Artery; GTP-Binding Proteins; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Species Specificity; Vasoconstriction	1988
Role of stimulatory GTP-binding protein (Gs) in reduced beta-adrenoceptor coupling in the femoral artery of spontaneously hypertensive rats. British journal of pharmacology, 1988, Volume: 95, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Antagonists; Animals; Bucladesine; Cholera Toxin; Colforsin; Femoral Artery; GTP-Binding Proteins; Guanosine Triphosphate; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Timolol	1988
Supersensitivity of beta-adrenoceptor coupled adenylate cyclase in pulmonary tissue of the spontaneously hypertensive rat. Life sciences, 1989, Volume: 45, Issue:22 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Guanylyl Imidodiphosphate; Hypertension; Isoproterenol; Lung; Male; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta	1989
Increased forskolin stimulation of lymphocyte-adenylate cyclase in normotensive subjects predisposed to essential hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6 Topics: Adenylyl Cyclases; Colforsin; Disease Susceptibility; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Humans; Hypertension; Lymphocytes; Male; Stimulation, Chemical	1989
[Anomalies of the adenylate cyclase system in platelets of the SHR rat]. Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No Topics: Adenylyl Cyclases; Animals; Blood Platelets; Cell Membrane; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypertension; Magnesium; Male; Manganese; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1988
Role of cyclic AMP protein kinase in decreased arterial cyclic AMP responsiveness in hypertension. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3 Topics: Animals; Aorta, Thoracic; Arteries; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Hypertension; Isoenzymes; Isoproterenol; Muscle, Smooth, Vascular; Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstriction	1985
Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats. Journal of molecular and cellular cardiology, 1987, Volume: 19, Issue:2 Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Isoproterenol; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sarcolemma; Thionucleotides	1987
Altered responsiveness of adenylate cyclase to adenosine and other agents in the myocardial sarcolemma and aorta of spontaneously-hypertensive rats. Biochemical pharmacology, 1988, Aug-01, Volume: 37, Issue:15 Topics: Adenosine; Adenylyl Cyclases; Animals; Aorta; Colforsin; Epinephrine; Female; Glucagon; Hypertension; In Vitro Techniques; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma	1988