ketorolac has been researched along with Hypertension in 6 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
---|---|---|
"This case report describes postoperative, reversible renal dysfunction and hypertension in a 5-year-old healthy boy after administration of relevant doses of ketorolac during anaesthesia." | 3.75 | [Ketorolac as a possible cause of reversible renal dysfunction in a 5-year-old child]. ( Knudsen, SM; Mantoni, T; Walther-Larsen, S, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Asirvatham-Jeyaraj, N | 1 |
Jones, AD | 1 |
Burnett, R | 1 |
Fink, GD | 1 |
Bordlee, JW | 1 |
Beakley, BD | 1 |
Mody, R | 1 |
McConville, AP | 1 |
Weed, JT | 1 |
McClure, BP | 1 |
Foldes, PJ | 1 |
Ma, JG | 1 |
Kaye, AD | 1 |
Eskander, JP | 1 |
Sitkin, SI | 1 |
Davydova, OB | 1 |
Kostin, IO | 1 |
Gasparian, AL | 1 |
Knudsen, SM | 1 |
Mantoni, T | 1 |
Walther-Larsen, S | 1 |
Rossi, P | 1 |
Nappi, G | 1 |
Carvajal, K | 1 |
El Hafidi, M | 1 |
BaƱos, G | 1 |
1 trial available for ketorolac and Hypertension
Article | Year |
---|---|
[Use of analgesia and sedation in dental implantology in patients with concomitant hypertension].
Topics: Anesthesia, Dental; Anesthesia, Local; Blood Pressure; Conscious Sedation; Dental Implantation; Fema | 2015 |
5 other studies available for ketorolac and Hypertension
Article | Year |
---|---|
Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Biomarkers; Brain; Chromatography, Liquid; Cyclooxygenas | 2019 |
A case of paradoxical presentation of a postural postdural puncture headache after combined spinal-epidural anesthesia.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, | 2017 |
[Ketorolac as a possible cause of reversible renal dysfunction in a 5-year-old child].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Hernia, Umbilical; Humans; Hypertension; | 2009 |
Bath-related headache: the first European case.
Topics: Adrenergic beta-Antagonists; Analgesics; Baths; Female; Headache; Humans; Hypertension; Ketorolac; M | 2006 |
Myocardial damage due to ischemia and reperfusion in hypertriglyceridemic and hypertensive rats: participation of free radicals and calcium overload.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Creatine Kinase; Cyclic N-Oxides; Free Radicals; Heart Rate; | 1999 |