aspartic acid has been researched along with Hypertension in 41 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
Excerpt | Relevance | Reference |
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"To explore the potential mechanism of acupuncture stimulation of "Taichong" (LR 3) and "Neiguan" (PC 6) in spontaneous hypertension rats (SHR) by investigating its effects on blood pressure and contents of aspartic acid(Asp) and glutamic acid (Glu) in the rostral ventrolateral medulla (RVLM) region." | 7.85 | [Effect of Acupuncture at "Taichong"(LR 3) and "Neiguan"(PC 6) on Blood Pressure and Contents of Aspartic Acid and Glutamic Acid in the Rostral Ventrolateral Medulla in Spontaneous Hypertension Rats]. ( Chen, YT; Lin, XM; Shen, PP; Xiao, SK; Yang, YY; Yao, W, 2017) |
"Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population." | 7.74 | N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008) |
"To explore the potential mechanism of acupuncture stimulation of "Taichong" (LR 3) and "Neiguan" (PC 6) in spontaneous hypertension rats (SHR) by investigating its effects on blood pressure and contents of aspartic acid(Asp) and glutamic acid (Glu) in the rostral ventrolateral medulla (RVLM) region." | 3.85 | [Effect of Acupuncture at "Taichong"(LR 3) and "Neiguan"(PC 6) on Blood Pressure and Contents of Aspartic Acid and Glutamic Acid in the Rostral Ventrolateral Medulla in Spontaneous Hypertension Rats]. ( Chen, YT; Lin, XM; Shen, PP; Xiao, SK; Yang, YY; Yao, W, 2017) |
"Our objective was to investigate the influence of hypertension on N-acetylaspartate (NAA) and choline (Cho) ratios in brain tissues in a community-dwelling elderly population." | 3.74 | N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. ( Aho, SL; Bejot, Y; Ben Salem, D; Brunotte, F; Ricolfi, F; Rouaud, O; Tavernier, B; Walker, PM, 2008) |
"In this study, cognitively intact chronic hypertensive older patients had a higher white matter myoinositol/creatine ratio compared with healthy older subjects, suggesting that myoinositol may be a sensitive marker of the effects of chronic hypertension on the brain." | 3.71 | Proton magnetic resonance spectroscopy reveals similar white matter biochemical changes in patients with chronic hypertension and early Alzheimer's disease. ( Benedetti, C; Catani, M; Cherubini, A; Howard, R; Mariani, E; Mecocci, P; Metastasio, A; Pelliccioli, GP; Senin, U; Tarducci, R, 2002) |
"Univariate ANOVA disclosed significant effects of AHI, age, and the presence or absence of hypertension on the NAA/choline ratio for cerebral white matter (p=0." | 3.71 | Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change. ( Chen, W; Higami, S; Inoue, Y; Kamba, M; Ogawa, T; Suto, Y, 2001) |
"Salt-induced hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | 1.72 | Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns. ( Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X, 2022) |
"Hypertension is associated with an increased risk of cognitive decline, which is generally regarded as a consequence of advanced cerebral atherosclerosis." | 1.37 | The impact of blood pressure on hippocampal glutamate and mnestic function. ( Gallinat, J; Joppke, M; Klär, AA; Schubert, F; Westhoff, TH; Wirth, C; Zidek, W, 2011) |
"Hypertension is associated with cognitive decline in elderly persons." | 1.36 | Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes. ( Antequera, M; Antúnez, C; Campoy, G; Carrillo, A; Fuentes, LJ; García Santos, JM; García-Sevilla, J; Ortega, G; Torres del Río, S; Vidal, JB, 2010) |
"Diabetes and hypertension are potent risk factors for cerebrovascular disease." | 1.33 | Diabetic brain damage in hypertension: role of renin-angiotensin system. ( Eguchi, K; Hoshide, S; Ishikawa, J; Ishikawa, S; Kario, K; Matsui, Y; Morinari, M; Shimada, K, 2005) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (24.39) | 18.7374 |
1990's | 8 (19.51) | 18.2507 |
2000's | 12 (29.27) | 29.6817 |
2010's | 6 (14.63) | 24.3611 |
2020's | 5 (12.20) | 2.80 |
Authors | Studies |
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Ahmad, H | 1 |
Zhao, X | 1 |
Ahmad, N | 1 |
Khan, A | 1 |
Jin, Y | 1 |
Du, J | 1 |
Zheng, X | 1 |
Zeng, L | 1 |
Ouyang, Y | 1 |
Yang, P | 1 |
Chen, M | 1 |
Li, X | 1 |
Yang, Z | 1 |
Tian, Z | 2 |
Todisco, S | 1 |
Musio, B | 1 |
Pesce, V | 1 |
Cavalluzzi, MM | 1 |
Petrosillo, G | 1 |
La Piana, G | 1 |
Sgobba, MN | 1 |
Schlosserová, N | 1 |
Cafferati Beltrame, L | 1 |
Di Lorenzo, R | 1 |
Tragni, V | 1 |
Marzulli, D | 1 |
Guerra, L | 1 |
De Grassi, A | 1 |
Gallo, V | 1 |
Volpicella, M | 1 |
Palese, LL | 1 |
Lentini, G | 1 |
Pierri, CL | 1 |
Zhou, JJ | 1 |
Shao, JY | 1 |
Chen, SR | 1 |
Pan, HL | 1 |
Verma, S | 2 |
Abbas, M | 1 |
Khan, FH | 1 |
Raza, ST | 1 |
Siddiqi, Z | 1 |
Ahmad, I | 1 |
Mahdi, F | 1 |
Ajamu, SO | 1 |
Fenner, RC | 1 |
Grigorova, YN | 1 |
Cezayirli, D | 1 |
Morrell, CH | 1 |
Lakatta, EG | 1 |
Bouhrara, M | 1 |
Spencer, RG | 1 |
Fedorova, OV | 1 |
Fishbein, KW | 1 |
Hou, E | 1 |
Sun, N | 1 |
Zhang, F | 1 |
Zhao, C | 1 |
Usa, K | 1 |
Liang, M | 1 |
Shen, PP | 1 |
Chen, YT | 1 |
Xiao, SK | 1 |
Yao, W | 1 |
Yang, YY | 1 |
Lin, XM | 1 |
Voronkov, LH | 1 |
Horovenko, NH | 1 |
Mazur, ID | 1 |
Liashenko, AV | 1 |
Inanir, A | 1 |
Basol, N | 1 |
Karakus, N | 1 |
Yigit, S | 1 |
Ben Salem, D | 1 |
Walker, PM | 1 |
Bejot, Y | 1 |
Aho, SL | 1 |
Tavernier, B | 1 |
Rouaud, O | 1 |
Ricolfi, F | 1 |
Brunotte, F | 1 |
García Santos, JM | 1 |
Fuentes, LJ | 1 |
Vidal, JB | 1 |
Carrillo, A | 1 |
Antequera, M | 1 |
Campoy, G | 1 |
Antúnez, C | 1 |
Torres del Río, S | 1 |
García-Sevilla, J | 1 |
Ortega, G | 1 |
Westhoff, TH | 1 |
Schubert, F | 1 |
Wirth, C | 1 |
Joppke, M | 1 |
Klär, AA | 1 |
Zidek, W | 1 |
Gallinat, J | 1 |
Catani, M | 1 |
Mecocci, P | 1 |
Tarducci, R | 1 |
Howard, R | 1 |
Pelliccioli, GP | 1 |
Mariani, E | 1 |
Metastasio, A | 1 |
Benedetti, C | 1 |
Senin, U | 1 |
Cherubini, A | 1 |
GUIDERI, R | 1 |
BIANCHI, V | 1 |
MELONI, C | 1 |
Kario, K | 1 |
Ishikawa, J | 1 |
Hoshide, S | 1 |
Matsui, Y | 1 |
Morinari, M | 1 |
Eguchi, K | 1 |
Ishikawa, S | 1 |
Shimada, K | 1 |
Wolff, B | 1 |
Grabe, HJ | 1 |
Schlüter, C | 1 |
Popowski, K | 1 |
Völzke, H | 1 |
Lüdemann, J | 1 |
John, U | 1 |
Felix, SB | 1 |
Cascorbi, I | 1 |
Golbang, AP | 1 |
Murthy, M | 1 |
Hamad, A | 1 |
Liu, CH | 1 |
Cope, G | 1 |
Van't Hoff, W | 1 |
Cuthbert, A | 1 |
O'Shaughnessy, KM | 1 |
Zhang, HJ | 1 |
Li, JS | 1 |
Wang, H | 1 |
Feng, YQ | 1 |
Moskau, S | 1 |
Farmand, S | 1 |
Semmler, A | 1 |
Wüllner, U | 1 |
Pohl, C | 1 |
Klockgether, T | 1 |
Linnebank, M | 1 |
Ormezzano, O | 1 |
Amar, J | 1 |
Mounier Vehier, C | 1 |
Cambien, F | 1 |
Poirier, O | 1 |
Chamontin, B | 1 |
François, P | 1 |
Mallion, JM | 1 |
Baguet, JP | 1 |
Srivastava, K | 1 |
Narang, R | 1 |
Sreenivas, V | 1 |
Das, S | 1 |
Das, N | 1 |
Nitkunan, A | 1 |
Charlton, RA | 1 |
McIntyre, DJ | 1 |
Barrick, TR | 1 |
Howe, FA | 1 |
Markus, HS | 1 |
Laborit, H | 1 |
Laborit, G | 1 |
Dyckner, T | 1 |
Wester, PO | 2 |
Plum-Wirell, M | 1 |
Stegmayr, BG | 1 |
Witteman, JC | 1 |
Grobbee, DE | 1 |
Derkx, FH | 1 |
Bouillon, R | 1 |
de Bruijn, AM | 1 |
Hofman, A | 1 |
Matsuura, A | 1 |
Okumura, H | 1 |
Asakura, R | 1 |
Ashizawa, N | 1 |
Takahashi, M | 1 |
Kobayashi, F | 1 |
Ashikawa, N | 1 |
Arai, K | 1 |
Zavagli, G | 1 |
Ricci, G | 1 |
Gilli, G | 1 |
Antolini, G | 1 |
Castaldi, G | 1 |
Kamba, M | 1 |
Inoue, Y | 1 |
Higami, S | 1 |
Suto, Y | 1 |
Ogawa, T | 1 |
Chen, W | 1 |
Karvonen, J | 1 |
Kauma, H | 1 |
Kervinen, K | 1 |
Rantala, M | 1 |
Ikäheimo, M | 1 |
Päivänsalo, M | 1 |
Savolainen, MJ | 1 |
Kesäniemi, YA | 1 |
Sebeková, K | 1 |
Revúsová, V | 1 |
Polakovicová, D | 1 |
Drahosová, J | 1 |
Zverková, D | 1 |
Dzúrik, R | 1 |
Ooboshi, H | 1 |
Yao, H | 1 |
Matsumoto, T | 1 |
Hirano, M | 1 |
Uchimura, H | 1 |
Sadoshima, S | 1 |
Fujishima, M | 1 |
Tingley, FD | 1 |
Arnerić, SP | 1 |
Zemel, PC | 1 |
Zemel, MB | 1 |
Urberg, M | 1 |
Douglas, FL | 1 |
Geiser, R | 1 |
Sowers, JR | 1 |
Verberne, AJ | 1 |
Lewis, SJ | 1 |
Jarrott, B | 1 |
Louis, WJ | 1 |
Cappuccio, FP | 1 |
Markandu, ND | 1 |
Beynon, GW | 1 |
Shore, AC | 1 |
Sampson, B | 1 |
MacGregor, GA | 1 |
Nagatsu, I | 1 |
Gillespie, L | 1 |
George, JM | 1 |
Folk, JE | 1 |
Glenner, GG | 1 |
Krüger, K | 1 |
Savenko, SN | 1 |
Vladkovskiĭ, IK | 1 |
Maidanik, FE | 1 |
Gavrilescu, S | 1 |
Danciu, T | 1 |
Fiat, F | 1 |
Pop, T | 1 |
Ehrlich, R | 1 |
2 reviews available for aspartic acid and Hypertension
Article | Year |
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Targeting mitochondrial impairment for the treatment of cardiovascular diseases: From hypertension to ischemia-reperfusion injury, searching for new pharmacological targets.
Topics: Adenosine Triphosphate; Aspartic Acid; Cardiovascular Diseases; Humans; Hypertension; Malates; Mitoc | 2023 |
[New experimental data on the physiopathology of myocardial necrosis and its treatment].
Topics: Animals; Aspartic Acid; Glucose; Hypertension; Insulin; Lysosomes; Myocardial Infarction; Potassium; | 1983 |
5 trials available for aspartic acid and Hypertension
Article | Year |
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Effect of magnesium on blood pressure.
Topics: Aged; Aspartic Acid; Blood Pressure; Calcium; Diuretics; Female; Heart Failure; Humans; Hypertension | 1983 |
Nutritional magnesium supplementation does not change blood pressure nor serum or muscle potassium and magnesium in untreated hypertension. A double-blind crossover study.
Topics: Administration, Oral; Adult; Aspartic Acid; Blood Pressure; Body Weight; Cross-Over Studies; Double- | 1994 |
Reduction of blood pressure with oral magnesium supplementation in women with mild to moderate hypertension.
Topics: Administration, Oral; Adult; Aged; Aspartic Acid; Blood Pressure; Body Weight; Diarrhea; Double-Blin | 1994 |
Metabolic and hemodynamic effects of magnesium supplementation in patients with essential hypertension.
Topics: Adult; Aged; Aspartic Acid; Blood Pressure; Diet; Double-Blind Method; Electrolytes; Erythrocytes; F | 1990 |
Lack of effect of oral magnesium on high blood pressure: a double blind study.
Topics: Adult; Aged; Aspartic Acid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertens | 1985 |
34 other studies available for aspartic acid and Hypertension
Article | Year |
---|---|
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; | 2022 |
Brain α2δ-1-Bound NMDA Receptors Drive Calcineurin Inhibitor-Induced Hypertension.
Topics: Animals; Aspartic Acid; Brain; Calcineurin Inhibitors; Gabapentin; Hypertension; Mice; Rats; Recepto | 2023 |
Impact of I/D polymorphism of angiotensin-converting enzyme 1 (ACE1) gene on the severity of COVID-19 patients.
Topics: Adult; Age Factors; Aged; Alleles; Amino Acid Substitution; Angiotensin-Converting Enzyme 2; Asparti | 2021 |
Association of central arterial stiffness with hippocampal blood flow and N-acetyl aspartate concentration in hypertensive adult Dahl salt sensitive rats.
Topics: Animals; Aspartic Acid; Blood Pressure; Hippocampus; Hypertension; Male; Pulse Wave Analysis; Rats; | 2021 |
Malate and Aspartate Increase L-Arginine and Nitric Oxide and Attenuate Hypertension.
Topics: Animals; Arginine; Aspartic Acid; Down-Regulation; Fumarate Hydratase; Gene Knockdown Techniques; Hy | 2017 |
[Effect of Acupuncture at "Taichong"(LR 3) and "Neiguan"(PC 6) on Blood Pressure and Contents of Aspartic Acid and Glutamic Acid in the Rostral Ventrolateral Medulla in Spontaneous Hypertension Rats].
Topics: Acupuncture Points; Acupuncture Therapy; Animals; Aspartic Acid; Blood Pressure; Disease Models, Ani | 2017 |
[I/D angiotensin-converting enzyme gene polymorphism: structural changes in the myocardium and predictive value in chronic heart failure].
Topics: Aged; Amino Acid Substitution; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; As | 2012 |
The importance of association between angiotensin-converting enzyme (ACE) Gene I/D polymorphism and diabetic peripheral neuropathy.
Topics: Aged; Alleles; Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Diabetic Neuropathies; | 2013 |
N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Biomarkers; Cerebral Cortex; Choline; Cognition Disor | 2008 |
Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes.
Topics: Aged; Antihypertensive Agents; Aspartic Acid; Atrophy; Brain; Brain Chemistry; Cerebral Hemorrhage; | 2010 |
The impact of blood pressure on hippocampal glutamate and mnestic function.
Topics: Adult; Aspartic Acid; Blood Pressure; Cognition; Cognition Disorders; Female; Germany; Glutamic Acid | 2011 |
Proton magnetic resonance spectroscopy reveals similar white matter biochemical changes in patients with chronic hypertension and early Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Choline; Chronic Disease; Creatine | 2002 |
[The hypotensive action of a new pharmacological compound with diuretic activity].
Topics: Acetazolamide; Aspartic Acid; Chlorothiazide; Diuretics; Hypertension | 1960 |
Diabetic brain damage in hypertension: role of renin-angiotensin system.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspartic Acid; Benzimidazoles; Biphenyl Compounds; Bl | 2005 |
Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample.
Topics: Adult; Aged; Aspartic Acid; Blood Pressure; Cohort Studies; Cross-Sectional Studies; Endothelium, Va | 2005 |
A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene.
Topics: Adult; Amino Acid Motifs; Animals; Aspartic Acid; Cell Membrane; Female; Genetic Testing; Histidine; | 2005 |
Determination of aspartate and glutamate in rabbit retina using polymer monolith microextraction coupled to high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Aspartic Acid; Calibration; Chromatography, High Pressure Liquid; Fluorescence; Glutamic Ac | 2006 |
The methionine synthase polymorphism c.2756A>G (D919G) influences diastolic blood pressure.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Alleles; Antihypertensive Ag | 2007 |
Association of eNOS Glu298Asp gene polymorphism with circadian blood pressure rhythm.
Topics: Adult; Aged; Aspartic Acid; Blood Pressure; Circadian Rhythm; Glutamic Acid; Humans; Hypertension; M | 2007 |
Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians.
Topics: Adult; Alleles; Aspartic Acid; Female; Genotype; Glutamic Acid; Humans; Hypertension; India; Male; M | 2008 |
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulati | 2008 |
Pharmacological profiles of aspergillomarasmines as endothelin converting enzyme inhibitors.
Topics: Animals; Aorta; Aspartic Acid; Aspartic Acid Endopeptidases; Cattle; Edetic Acid; Endothelin-Convert | 1993 |
An easy diagnostic approach to primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aspartic Acid; Blood Pressure; Diagnosis, Differential; Fem | 1999 |
Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Body Mass Index; Brain Chemistry; Cerebral Cortex; | 2001 |
Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort.
Topics: Alleles; Aspartic Acid; Blood Pressure; Carotid Stenosis; Case-Control Studies; Cohort Studies; Cros | 2002 |
Anti-hypertensive treatment with magnesium-aspartate-dichloride and its influence on peripheral serotonin metabolism in man: a subacute study.
Topics: Antihypertensive Agents; Aspartic Acid; Blood Platelets; Blood Pressure; Drug Combinations; Female; | 1992 |
Excitatory and inhibitory amino acid changes in ischemic brain regions in spontaneously hypertensive rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Aci | 1991 |
Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.
Topics: Amino Acids; Animals; Aspartic Acid; Clonidine; Female; gamma-Aminobutyric Acid; Glutamates; Glutami | 1990 |
Medial prefrontal cortical lesions and baroreceptor heart rate reflex sensitivity in the spontaneously hypertensive rat.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Heart Rate; Hypertension; Male; N-Methylaspartate; Pressore | 1988 |
Serum aminopeptidases, "angiotensinase," and hypertension. II. Amino acid beta-napthylamide hydrolysis by normal and hypertensive serum.
Topics: Aminopeptidases; Angiotensin II; Aspartic Acid; Colorimetry; Endopeptidases; Enzymes; Female; Humans | 1965 |
[Metabolic therapeutic possibilities of ischemic heart disease].
Topics: Angina Pectoris; Aspartic Acid; Coronary Disease; Electrocardiography; Female; Humans; Hypertension; | 1967 |
[The serum amino acid spectrum of hypertensive patients with cerebral circulatory disorders].
Topics: Adult; Aged; Alanine; Amino Acids; Arginine; Aspartic Acid; Cerebrovascular Disorders; Female; Human | 1971 |
Effect of potassium and tris-aspartate on heparin-induced serum free-fatty-acids evaluation, in man.
Topics: Aged; Arteriosclerosis; Aspartic Acid; Blood Glucose; Cholesterol; Coronary Disease; Fatty Acids, No | 1970 |
[Regulation of metabolism--a principle of cardi treatment].
Topics: Adenosine Triphosphate; Adult; Aged; Arrhythmias, Cardiac; Aspartic Acid; Blood Pressure; Electrocar | 1969 |