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dantrolene and Hypertension

dantrolene has been researched along with Hypertension in 4 studies

Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Stabilizing RyR with chronic dantrolene treatment does not affect hypertension development in SHR."7.96Chronic Dantrolene Treatment Does Not Affect Hypertension, but Attenuates Sympathetic Stimulation Enhanced Atrial Fibrillation Inducibility in SHR. ( Gerdes, AM; Greco, L; Lee, JS; Li, Y; Migirov, A; Zhang, Y, 2020)
"Stabilizing RyR with chronic dantrolene treatment does not affect hypertension development in SHR."3.96Chronic Dantrolene Treatment Does Not Affect Hypertension, but Attenuates Sympathetic Stimulation Enhanced Atrial Fibrillation Inducibility in SHR. ( Gerdes, AM; Greco, L; Lee, JS; Li, Y; Migirov, A; Zhang, Y, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Lee, JS1
Greco, L1
Migirov, A1
Li, Y1
Gerdes, AM1
Zhang, Y1
Lee, JH1
Zhang, J1
Flores, L1
Rose, JC1
Massmann, GA1
Figueroa, JP1
Newmark, JL1
Voelkel, M1
Brandom, BW1
Wu, J1
Adnet, P1
Krivosic-Horber, R1

Reviews

1 review available for dantrolene and Hypertension

ArticleYear
[Calcium inhibitors and anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:6

    Topics: Analgesics; Anesthesia, General; Anesthetics; Arrhythmias, Cardiac; Brain Ischemia; Calcium Channel

1988

Other Studies

3 other studies available for dantrolene and Hypertension

ArticleYear
Chronic Dantrolene Treatment Does Not Affect Hypertension, but Attenuates Sympathetic Stimulation Enhanced Atrial Fibrillation Inducibility in SHR.
    American journal of hypertension, 2020, 04-29, Volume: 33, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Dantrolene; Disease Models, An

2020
Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Blood Pressure; Dantrolene; Dose-Response Relation

2013
Delayed onset of malignant hyperthermia without creatine kinase elevation in a geriatric, ryanodine receptor type 1 gene compound heterozygous patient.
    Anesthesiology, 2007, Volume: 107, Issue:2

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Antihypertensive Agents; Blood Pressure; Colosto

2007