Page last updated: 2024-10-20

propionic acid and Hypertension

propionic acid has been researched along with Hypertension in 9 studies

propionic acid : A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
" Recently, tryptophan metabolites have been identified to contribute to and inhibit the progression of metabolic disorders and cardiovascular diseases, including hypertension."8.31Indole Propionic Acid Increases T Regulatory Cells and Decreases T Helper 17 Cells and Blood Pressure in Mice with Salt-Sensitive Hypertension. ( Alaniz, RC; Arenaz, CM; Baranwal, G; Creed, HA; Goodlett, BL; Mitchell, BM; Navaneethabalakrishnan, S; Rutkowski, JM, 2023)
" Recently, tryptophan metabolites have been identified to contribute to and inhibit the progression of metabolic disorders and cardiovascular diseases, including hypertension."4.31Indole Propionic Acid Increases T Regulatory Cells and Decreases T Helper 17 Cells and Blood Pressure in Mice with Salt-Sensitive Hypertension. ( Alaniz, RC; Arenaz, CM; Baranwal, G; Creed, HA; Goodlett, BL; Mitchell, BM; Navaneethabalakrishnan, S; Rutkowski, JM, 2023)
" Susceptibility to cardiac ventricular arrhythmias was significantly reduced in propionate-treated angiotensin II-infused wild-type NMRI mice."3.91Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage. ( Avery, EG; Balogh, A; Bartolomaeus, H; Dechend, R; Eckardt, KU; Fielitz, J; Forslund, SK; Gollasch, M; Grandoch, M; Haase, N; Hering, L; Höges, S; Homann, S; Kempa, S; Kozhakhmetov, S; Kräker, K; Krannich, A; Kusche-Vihrog, K; Kushugulova, A; Maase, M; Markó, L; Müller, DN; Rump, LC; Stegbauer, J; Tsvetkov, D; Wilck, N; Wundersitz, S; Yakoub, M; Zhumadilov, Z, 2019)
"Sex influences the effect of hypertension on the rate of swelling of platelets exposed to sodium propionate (pH 6."3.69Influence of sex on sodium-proton exchange-dependent swelling of platelets from patients with essential hypertension. ( Ritter, JM; Stratton, PD, 1997)
"In conclusion, improvement of hyperinsulinemia can decrease NHE activity and blood pressure in fructose-fed BHR."1.32Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats. ( Fujioka, Y; Iwasaki, T; Masai, M; Morimoto, S; Ohyanagi, M; Okumura, T; Tsuboi, S; Tsujino, T, 2003)
"Cirazoline did not produce a significant depolarisation in blood vessels of either normotensive or hypertensive rats."1.32Effects of chloride substitution on electromechanical responses in the pulmonary artery of Dahl normotensive and hypertensive rats. ( Bieger, D; Duggan, JA; Tabrizchi, R, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Baranwal, G1
Goodlett, BL1
Arenaz, CM1
Creed, HA1
Navaneethabalakrishnan, S1
Rutkowski, JM1
Alaniz, RC1
Mitchell, BM1
Bier, A1
Braun, T1
Khasbab, R1
Di Segni, A1
Grossman, E1
Haberman, Y1
Leibowitz, A1
Bartolomaeus, H1
Balogh, A1
Yakoub, M1
Homann, S1
Markó, L1
Höges, S1
Tsvetkov, D1
Krannich, A1
Wundersitz, S1
Avery, EG1
Haase, N1
Kräker, K1
Hering, L1
Maase, M1
Kusche-Vihrog, K1
Grandoch, M1
Fielitz, J1
Kempa, S1
Gollasch, M1
Zhumadilov, Z1
Kozhakhmetov, S1
Kushugulova, A1
Eckardt, KU1
Dechend, R1
Rump, LC1
Forslund, SK1
Müller, DN1
Stegbauer, J1
Wilck, N1
Pluznick, JL1
Protzko, RJ1
Gevorgyan, H1
Peterlin, Z1
Sipos, A1
Han, J1
Brunet, I1
Wan, LX1
Rey, F1
Wang, T1
Firestein, SJ1
Yanagisawa, M1
Gordon, JI1
Eichmann, A1
Peti-Peterdi, J1
Caplan, MJ1
Fujioka, Y1
Masai, M1
Tsuboi, S1
Okumura, T1
Morimoto, S1
Tsujino, T1
Ohyanagi, M1
Iwasaki, T1
ANNONI, G1
Bieger, D1
Duggan, JA1
Tabrizchi, R1
Stratton, PD1
Ritter, JM1
Weder, AB1
Schmouder, RL1
Torretti, BA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Mechanisms Linking Dietary Fiber, the Microbiome and Satiety[NCT04611217]88 participants (Anticipated)Interventional2021-04-22Recruiting
Prebiotic Therapy to Improve Outcomes of Renal Transplant[NCT04428190]Early Phase 160 participants (Anticipated)Interventional2022-02-23Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for propionic acid and Hypertension

ArticleYear
Indole Propionic Acid Increases T Regulatory Cells and Decreases T Helper 17 Cells and Blood Pressure in Mice with Salt-Sensitive Hypertension.
    International journal of molecular sciences, 2023, May-24, Volume: 24, Issue:11

    Topics: Animals; Blood Pressure; Cardiovascular Diseases; Hypertension; Indoles; Mice; Sodium; Sodium Chlori

2023
A High Salt Diet Modulates the Gut Microbiota and Short Chain Fatty Acids Production in a Salt-Sensitive Hypertension Rat Model.
    Nutrients, 2018, Aug-23, Volume: 10, Issue:9

    Topics: Acetic Acid; Actinomycetales; Animals; Blood Pressure; Butyric Acid; Clostridiales; Diet; Erwinia; F

2018
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
    Circulation, 2019, 03-12, Volume: 139, Issue:11

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial P

2019
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
    Circulation, 2019, 03-12, Volume: 139, Issue:11

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial P

2019
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
    Circulation, 2019, 03-12, Volume: 139, Issue:11

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial P

2019
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
    Circulation, 2019, 03-12, Volume: 139, Issue:11

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial P

2019
Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Mar-12, Volume: 110, Issue:11

    Topics: Animals; Biomass; Blood Pressure; Gene Expression Regulation; Hypertension; Intestinal Mucosa; Intes

2013
Troglitazone reduces activity of the Na+/H+ exchanger in fructose-fed borderline hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:1

    Topics: Animals; Bezafibrate; Blood Glucose; Blood Platelets; Blood Pressure; Calcium; Chromans; Diet; Eicos

2003
[ACTION OF A SYNTHETIC ANTICHOLESTEROLEMIC DRUG, 2-(4-BIPHENYLYL)-PROPIONIC ACID, IN OBESITY].
    La Clinica terapeutica, 1963, Aug-15, Volume: 26

    Topics: Antimetabolites; Biphenyl Compounds; Cholesterol; Coronary Disease; Humans; Hypertension; Obesity; P

1963
Effects of chloride substitution on electromechanical responses in the pulmonary artery of Dahl normotensive and hypertensive rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Chlorides; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors;

2004
Influence of sex on sodium-proton exchange-dependent swelling of platelets from patients with essential hypertension.
    Journal of hypertension, 1997, Volume: 15, Issue:12 Pt 1

    Topics: Adult; Blood Platelets; Female; Humans; Hypertension; Male; Middle Aged; Propionates; Reference Valu

1997
Platelet volume responses to cytoplasmic acidification in essential hypertension.
    Journal of hypertension, 1990, Volume: 8, Issue:12

    Topics: Adult; Amiloride; Blood Platelets; Calcium; Carrier Proteins; Female; Humans; Hydrogen-Ion Concentra

1990