Page last updated: 2024-12-08
citrulline malate
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Occurs in Manufacturing
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Description
citrulline malate: an anti-fatigue cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 162762 |
| CHEMBL ID | 4297667 |
| SCHEMBL ID | 319676 |
| MeSH ID | M0193424 |
Synonyms (39)
| Synonym |
|---|
| stimol (tn) |
| citrulline malate |
| 54940-97-5 |
| D07707 |
| (2s)-2-amino-5-(carbamoylamino)pentanoic acid; 2-hydroxybutanedioic acid |
| A830416 |
| (2s)-2-amino-5-ureido-pentanoic acid; 2-hydroxybutanedioic acid |
| AKOS015919504 |
| l-citrulline dl-malate (1:1) |
| 70796-17-7 |
| unii-pab4036kho |
| stimol |
| pab4036kho , |
| l-ornithine, n5-(aminocarbonyl)-, 2-hydroxybutanedioate (1:1) |
| l-citrulline dl-malate |
| l-ornithine, n5-(aminocarbonyl)-, hydroxybutanedioate (1:1) |
| citrulline malate [who-dd] |
| SCHEMBL319676 |
| l-citrulline-dl-malate |
| mfcd09839004 |
| GS-3899 |
| l-citrulline dl-malate(1:1) |
| (2s)-2-amino-5-(carbamoylamino)pentanoic acid;2-hydroxybutanedioic acid |
| citrulline malate (salt) [mi] |
| (s)-2-amino-5-ureidopentanoic acid 2-hydroxysuccinic acid salt |
| BCP11994 |
| l-citrulline dl-malate 2:1 |
| 2-hydroxybutanedioic acid--n~5~-[hydroxy(imino)methyl]ornithine (1/1) |
| DTXSID60970275 |
| Q27286437 |
| di-tert-butyl1-(tert-butylthio)-1,2-hydrazinedicarboxylate |
| CHEMBL4297667 |
| citrulline malate (salt) |
| l-citrulline malate |
| (s)-2-amino-5-ureidopentanoic acid compound with 2-hydroxysuccinic acid (1:1) |
| A914153 |
| l-citrulline,dl-malate |
| CS-0083737 |
| HY-N0391A |
Research Excerpts
Overview
Citrulline malate (CitMal) is a dietary supplement that is suggested to enhance strength training performance. It is a nonessential amino acid that increases exercise performance in males.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Citrulline malate (CitMal) is a dietary supplement that is suggested to enhance strength training performance. " | ( Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis. Bjørnsen, T; Gonzalez, AM; Vårvik, FT, 2021) | 2.41 |
| "Citrulline malate (CM) is a nonessential amino acid that increases exercise performance in males. " | ( Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained females. Glenn, JM; Gray, M; Moyen, NE; Stewart, RW; Stone, MS; Wethington, LN, 2017) | 2.38 |
Effects
| Excerpt | Reference | Relevance |
|---|---|---|
| "Citrulline malate (CM) has been shown to improve muscle performance in healthy participants during a single exercise session. " | ( Effect of citrulline malate supplementation on muscle function and bioenergetics during short-term repeated bouts of fatiguing exercise. Bendahan, D; Giannesini, B; Meimoun, L; Pecchi, É; Vilmen, C, 2022) | 2.57 |
Treatment
| Excerpt | Reference | Relevance |
|---|---|---|
| "Oral treatment by citrulline malate was found to increase resistance to fatigue in infected rats, whereas twitch tension was not modified." | ( Citrulline malate limits increase in muscle fatigue induced by bacterial endotoxins. Allaf, O; Gillardin, JM; Goubel, F; Vanhoutte, C; Verleye, M, 1997) | 2.06 |
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| " Further exploration of the optimal dose is therefore required including quantification of the bioavailability of NO, citrulline, and malate following ingestion of a range of CM doses." | ( A critical review of citrulline malate supplementation and exercise performance. Bridge, CA; Faghy, MA; Gough, LA; Higgins, MF; McNaughton, LR; Newbury, JW; Sparks, SA; Trexler, E, 2021) | 0.94 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " The most frequent dosage used in the studies was 8 g of citrulline malate." | ( Effect of citrulline on post-exercise rating of perceived exertion, muscle soreness, and blood lactate levels: A systematic review and meta-analysis. Jang, KM; Kim, SJ; Park, J; Rhim, HC, 2020) | 0.8 |
| " Reasons for the disparity in conclusions seem to be due to methodological discrepancies such as the testing protocols and the associated test-retest reliability, dosing strategy (i." | ( A critical review of citrulline malate supplementation and exercise performance. Bridge, CA; Faghy, MA; Gough, LA; Higgins, MF; McNaughton, LR; Newbury, JW; Sparks, SA; Trexler, E, 2021) | 0.94 |
| " Eighteen recreationally trained males consumed both a placebo (PL) and CM treatment for two separate dosing periods." | ( Acute and Chronic Citrulline Malate Supplementation on Muscle Contractile Properties and Fatigue Rate of the Quadriceps. Farney, TM; Fick, AN; Hearon, CM; Kowalsky, RJ; Stone, MS, 2021) | 0.96 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Occurs in Manufacturing (21 Product(s))
Product Categories
| Product Category | Products |
|---|---|
| Other | 2 |
| Beverages | 1 |
| Active Lifestyle & Fitness | 14 |
| Vitamins & Supplements | 4 |