Page last updated: 2024-12-05
phosfolan
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
phosfolan: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 13689 |
| CHEBI ID | 82145 |
| SCHEMBL ID | 122109 |
| MeSH ID | M0042849 |
Synonyms (73)
| Synonym |
|---|
| phosphoramidic acid, n-1,3-dithiolan-2-ylidene-, diethyl ester |
| chj98j84ay , |
| unii-chj98j84ay |
| phosphoramidic acid, 1,3-dithiolan-2-ylidene-, diethyl ester |
| phosfolan |
| 1,2-ethanedithiol, cyclic ester with p,p-diethyl phosphonodithioimidocarbonate |
| american cyanamide 47031 |
| american cyanamid 47031 |
| (diethoxyphosphinyl)dithioimidocarbonic acid cyclic ethylene ester |
| ei 47031 |
| diethyl 1,3-dithiolan-2-ylidenephosphoramidate |
| phospholan |
| ac 47031 |
| cyclic ethylene(diethoxyphosphinothioyl)dithioimidocarbonate |
| imidocarbonic acid, (diethoxyphosphinyl)dithio-, cyclic ethylene ester |
| imidocarbonic acid, phosphonodithio-, cyclic ethylene p,p-diethyl ester |
| cyolane insecticide |
| p,p-diethyl cyclic ethylene ester of phosphonodithioimidocarbonic acid |
| 1,2-ethanedithiol, cyclic s,s-ester with phosphonodithioimidocarbonic acid p,p-diethyl ester |
| epa pesticide chemical code 268300 |
| p,p-diethyl cyclic ethylene phosphonodithioimidocarbonate |
| cyolane |
| cyclic ethylene-p,p-diethyl phosphonodithioimidocarbonate |
| phospholan [iso-french] |
| oms 646 |
| caswell no. 268b |
| american cyanamid ac 47,031 |
| phosfolan [bsi:iso] |
| ent 25,830 |
| cl 47031 |
| 2-(diethoxyphosphinylimino)-1,3-dithiolane |
| ai3-25830 |
| american cyanamid cl-47031 |
| einecs 213-423-2 |
| imidocarbonic acid, phosphonodithio-, p,p-diethyl cyclic ethylene ester |
| hsdb 2824 |
| cyclic ethylene p,p-diethyl phosphonodithioimidocarbonate |
| n-diethoxyphosphoryl-1,3-dithiolan-2-imine |
| 947-02-4 |
| C19011 |
| NCGC00255841-01 |
| dtxcid9022285 |
| tox21_301905 |
| cas-947-02-4 |
| dtxsid1042285 , |
| AKOS015960698 |
| SCHEMBL122109 |
| phosfolan [mi] |
| 1,3-dithiolan-2-ylidenephosphoramidic acid diethyl ester |
| cl-47031 |
| ei-47031 |
| american cyanamide-47031 |
| diethyl n-1,3-dithiolan-2-ylidenephosphoramidate |
| phosfolan [iso] |
| ac-47031 |
| ent-25,830 |
| phosfolan [hsdb] |
| CHEBI:82145 |
| cyalane |
| diethyl 1,3-dithiolan-2-ylideneamidophosphate # |
| 2-[(diethoxyphosphinyl)imino]-1,3-dithiolane |
| ILBONRFSLATCRE-UHFFFAOYSA-N |
| 1,2-ethanedithiol, cyclic s,s-ester with phosphonodithioimidocarbonic acid o,o-diethyl ester |
| cayolan |
| ci-47031 |
| cyolane cylan |
| cyolan |
| imidocarbonic acid, phosphonodithio-, o,o-diethyl cyclic ethylene ester |
| phosfolan 100 microg/ml in cyclohexane |
| diethyl (1,3-dithiolan-2-ylidene)phosphoramidate |
| Q7187417 |
| phosfolan 1000 microg/ml in acetone |
| STARBLD0001836 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " It is believed that the phosphonate ester configuration of EPN and Leptophos has a specific mode of toxic action which is mainly located at the central nervous system." | ( Neurotoxicity of organophosphorus insecticides Leptophos and EPN. Ahmed, NS; El-Sebae, AH; Elamayem, MA; Soliman, SA, 1977) | 0.26 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| phosphoric ester | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Protein Targets (2)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 44.7853 | 0.0025 | 41.7960 | 15,848.9004 | AID1347395; AID1347398 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 68.5896 | 0.0007 | 14.5928 | 83.7951 | AID1259369 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 20.04
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (20.04) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||