3-methylmethcathinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-methylmethcathinone: synthetic street drug, structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	71741532
SCHEMBL ID	20472228
MeSH ID	M000602877

Synonyms (18)

Synonym
mepedrone
1246816-62-5
QDNXSIYWHYGMCD-UHFFFAOYSA-N
3-methylmethcathinone
73q9qto1n4 ,
2-(methylamino)-1-(3-methylphenyl)-1-propanone
2-(methylamino)-1-(3-methylphenyl)propan-1-one
1-propanone, 2-(methylamino)-1-(3-methylphenyl)-
unii-73q9qto1n4
3-mmc
3-methylmethcathinone (hydrochloride)
SCHEMBL20472228
3-methylmethcathinone (3-mmc)
FT-0701142
Q27266198
1246911-86-3
PD048123
DTXSID401043421

Research Excerpts

Pharmacokinetics

Excerpt	Reference	Relevance
" The lack of pharmacological data on 3-MMC, prompted us to explore its pharmacokinetic profile as well as its effect on feeding behavior, weight gain, and serum biochemistry."	( 3-Methyl-methcathinone: Pharmacokinetic profile evaluation in pigs in relation to pharmacodynamics. Britzi, M; Edery, N; Nutt, D; Shimshoni, JA; Sobol, E; Willenz, U, 2015)	0.42

Bioavailability

Excerpt	Reference	Relevance
" The bioavailability was about 7%."	( 3-Methyl-methcathinone: Pharmacokinetic profile evaluation in pigs in relation to pharmacodynamics. Britzi, M; Edery, N; Nutt, D; Shimshoni, JA; Sobol, E; Willenz, U, 2015)	0.42

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	14 (82.35)	24.3611
2020's	3 (17.65)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 90.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	90.67 (24.57)
Research Supply Index	2.89 (2.92)
Research Growth Index	4.58 (4.65)
Search Engine Demand Index	157.97 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (90.67)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (11.76%)	6.00%
Case Studies	5 (29.41%)	4.05%
Observational	0 (0.00%)	0.25%
Other	10 (58.82%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
monomethylpropion monomethylpropion: metabolite of dimethylpropion; structure given in first source. 2-methylamino-1-phenylpropan-1-one : An aromatic ketone that is propiophenone in which the hydrogen alpha- to the keto group has been replaced by a methylamino group.. methcathinone : A racemate comprising equal amounts of (R)- and (S)-methcathinone.	2.59	2	aromatic ketone; secondary amino compound
methadone Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3). methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.. 6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.	2.21	1	benzenes; diarylmethane; ketone; tertiary amino compound
4-hydroxybutyric acid 4-hydroxybutyric acid: was an entry term to Sodium Oxybate (74-98). 4-hydroxybutyric acid : A 4-hydroxy monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a hydroxy group.	2.13	1	4-hydroxy monocarboxylic acid; hydroxybutyric acid	general anaesthetic; GHB receptor agonist; neurotoxin; sedative
methamphetamine Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.	5.91	16	amphetamines; secondary amine	central nervous system stimulant; environmental contaminant; neurotoxin; psychotropic drug; xenobiotic
cathinone cathinone: alkaloid from khat shrub, Catha edulis; RN given refers to parent cpd without isomeric designation. cathinone : The S stereoisomer of 2-aminopropiophenone.	2.82	3	2-aminopropiophenone; monoamine alkaloid	central nervous system stimulant; psychotropic drug
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	2.1	1
betadex beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.	2.17	1	cyclodextrin
5-APB 5-(2-aminopropyl)benzofuran: structure in first source	2.1	1	benzofurans
sodium oxybate Sodium Oxybate: The sodium salt of 4-hydroxybutyric acid. It is used for both induction and maintenance of ANESTHESIA.	3.41	1
mephedrone mephedrone: a beta-keto (bk) designer drug; Central Nervous System Stimulants. mephedrone : An aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes.	2.83	3	amphetamines; aromatic ketone; secondary amino compound	environmental contaminant; xenobiotic
methylone [no description available]	2.54	2	benzodioxoles
4-methylethcathinone 4-methylethcathinone: structure in first source	2.15	1	aromatic ketone
pentedrone pentedrone: structure in first source	2.21	1

Condition	Relationship Strength	Studies
Blood Pressure, High [description not available]	2.41	1
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	2.41	1
Poisoning Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.	7.41	1
Drug Overdose Accidental or deliberate use of a medication or street drug in excess of normal dosage.	3.76	3
Chemical Dependence [description not available]	3.03	4
Substance-Related Disorders Disorders related to substance use or abuse.	3.03	4
Amphetamine Abuse [description not available]	3.48	2
Amphetamine-Related Disorders Disorders related or resulting from use of amphetamines.	3.48	2
Addiction, Opioid [description not available]	2.21	1
Opioid-Related Disorders Disorders related to or resulting from abuse or misuse of OPIOIDS.	2.21	1
Alcohol Drinking Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.	2.1	1
Weight Gain Increase in BODY WEIGHT over existing weight.	2.11	1

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