Page last updated: 2024-08-21

oleanolic acid and Hypertension

oleanolic acid has been researched along with Hypertension in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's9 (75.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Jiang, H; Li, Y; Liu, Y; Qi, D; Tian, Z; Wang, X; Zhang, S1
Chartoumpekis, DV; Crawford, DR; Dolan, PM; Egner, PA; Groopman, JD; Ilic, Z; Johnson, NM; Kensler, KH; Kensler, TW; Sell, S; Slocum, SL1
Madlala, HP; Mubagwa, K; Musabayane, CT; Van Heerden, FR1
Bian, ZY; Feng, H; Liao, HH; Ma, ZG; Tang, QZ; Yang, Z; Yuan, Y; Zhang, N1
Dessy, C; Madlala, HP; Metzinger, T; Mubagwa, K; Musabayane, CT; van Heerden, FR1
Dinda, AK; Gupta, YK; Maulik, SK; Prabhakar, P; Reeta, KH1
Ranjbar, B; Taghdir, M; Tavassoli, Z1
Gotoh, T; Hiwatashi, K; Hori, K; Shinbo, M; Takahashi, S; Yamada, S1
Alvarado-Castillo, C; Cardozo, A; Estrada, O; Fernández, AZ; González-Guzmán, JM; Salazar-Bookaman, M1
Bachhav, SS; Bhutada, MS; Patil, SD; Surana, SJ1
Abramowitz, MK; Bauer, C; Hostetter, TH; Melamed, ML; Turner, JM1
de Sotomayor, MA; Herrera, MD; Rodriguez-Rodriguez, R; Ruiz-Gutierrez, V1

Reviews

1 review(s) available for oleanolic acid and Hypertension

ArticleYear
Treatment of chronic kidney disease.
    Kidney international, 2012, Volume: 81, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diabetes Mellitus, Type 2; Disease Progression; Endothelin-1; Humans; Hypertension; Kidney Failure, Chronic; Oleanolic Acid; Pyridones; Renal Insufficiency, Chronic; Renin-Angiotensin System

2012

Other Studies

11 other study(ies) available for oleanolic acid and Hypertension

ArticleYear
Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory phospholipase A2 and fatty acid synthase in spontaneously hypertensive rats.
    International journal of molecular medicine, 2020, Volume: 46, Issue:6

    Topics: Animals; Antihypertensive Agents; Biomarkers; Diastole; Discriminant Analysis; Down-Regulation; Fatty Acid Synthases; Hypertension; Least-Squares Analysis; Lipidomics; Lipids; Liver; Male; Metabolic Networks and Pathways; Metabolome; Multivariate Analysis; Oleanolic Acid; Phospholipases A2, Secretory; Rats, Inbred SHR; ROC Curve; Systole

2020
Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 139, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Aflatoxin B1; Animals; Cytoskeletal Proteins; Glutathione Transferase; Hepatocytes; Hypertension; Imidazoles; Kelch-Like ECH-Associated Protein 1; Liver; Mice, Inbred C57BL; Mice, Knockout; Mutagens; NF-E2-Related Factor 2; Oleanolic Acid; Signal Transduction

2014
Changes in Renal Function and Oxidative Status Associated with the Hypotensive Effects of Oleanolic Acid and Related Synthetic Derivatives in Experimental Animals.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Aldosterone; Animals; Antihypertensive Agents; Antioxidants; Arginine Vasopressin; Blood Pressure; Glutathione Peroxidase; Hypertension; Kidney Tubules, Proximal; Lithium Chloride; Male; Malondialdehyde; Oleanolic Acid; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Sodium; Sodium Chloride; Superoxide Dismutase; Syzygium

2015
Oleanolic acid alleviated pressure overload-induced cardiac remodeling.
    Molecular and cellular biochemistry, 2015, Volume: 409, Issue:1-2

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cardiomegaly; Diabetic Cardiomyopathies; Echocardiography; Fibrosis; Glucose; Hypertension; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oleanolic Acid; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Ventricular Remodeling

2015
Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Antihypertensive Agents; Endothelium, Vascular; Hypertension; Hypotension; Indomethacin; Male; Muscle Cells; Muscle, Smooth, Vascular; Nitroarginine; Oleanolic Acid; Phenylephrine; Potassium Channels; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Dahl; Rats, Wistar

2016
α-Amyrin attenuates high fructose diet-induced metabolic syndrome in rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:1

    Topics: Administration, Oral; Animals; Antihypertensive Agents; Antioxidants; Diet, Carbohydrate Loading; Dose-Response Relationship, Drug; Fructose; Gene Expression Regulation; Hyperglycemia; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Liver; Male; Metabolic Syndrome; Oleanolic Acid; Oxidative Stress; PPAR alpha; Random Allocation; Rats, Wistar

2017
Renin inhibition by soyasaponin I: a potent native anti-hypertensive compound.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:1

    Topics: Antihypertensive Agents; Catalytic Domain; Humans; Hypertension; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Oleanolic Acid; Protein Binding; Renin; Renin-Angiotensin System; Saponins; Thermodynamics

2018
Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:12

    Topics: Amino Acid Sequence; Animals; Blood Pressure; Enzyme Inhibitors; Glycine max; Humans; Hypertension; Inhibitory Concentration 50; Kinetics; Male; Oleanolic Acid; Rats; Renin; Saponins

2008
Pomolic acid of Licania pittieri elicits endothelium-dependent relaxation in rat aortic rings.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Apr-15, Volume: 18, Issue:6

    Topics: Animals; Antihypertensive Agents; Aorta; Apyrase; Atropine; Chrysobalanaceae; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Indomethacin; Male; Norepinephrine; Oleanolic Acid; Phytotherapy; Plant Extracts; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Purinergic; Signal Transduction; Vasoconstriction; Vasodilator Agents

2011
Oleanolic acid prevents glucocorticoid-induced hypertension in rats.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:10

    Topics: Animals; Blood Pressure; Body Weight; Dexamethasone; Glucocorticoids; Heart; Hypertension; Lipid Peroxidation; Male; Nitrates; Nitrites; Oleanolic Acid; Organ Size; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Thymus Gland; Viscum

2011
Pomace olive oil improves endothelial function in spontaneously hypertensive rats by increasing endothelial nitric oxide synthase expression.
    American journal of hypertension, 2007, Volume: 20, Issue:7

    Topics: Animals; Endothelium, Vascular; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oleanolic Acid; Olive Oil; Plant Oils; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2007