chloroquine has been researched along with Hypertension in 14 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proliferation of aortic smooth muscle cells (ASMC) of Wistar rats, impaired by risk factors such as arterial hypertension, diabetes mellitus, atherogenic diet and staphylolysin injections and of normal Wistar rats treated with antirheumatic drugs such as prednisolone and acetylsalicylic acid was investigated." | 3.66 | Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells. ( Hauss, WH; Mey, J; Schulte, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, K | 1 |
| Sun, Z | 1 |
| Askin, L | 1 |
| Tanrıverdi, O | 1 |
| Askin, HS | 1 |
| Li, HP | 1 |
| Liu, JT | 1 |
| Chen, YX | 1 |
| Wang, WB | 1 |
| Han, Y | 1 |
| Yao, QP | 1 |
| Qi, YX | 1 |
| Ambrosino, I | 1 |
| Barbagelata, E | 1 |
| Corbi, G | 1 |
| Ciarambino, T | 1 |
| Politi, C | 1 |
| Moretti, AM | 1 |
| Verdecchia, P | 1 |
| Angeli, F | 1 |
| Reboldi, G | 1 |
| McCarthy, CG | 2 |
| Wenceslau, CF | 2 |
| Goulopoulou, S | 2 |
| Baban, B | 1 |
| Matsumoto, T | 2 |
| Webb, RC | 2 |
| Ogbi, S | 1 |
| Singh, MV | 1 |
| Müller-Höcker, J | 1 |
| Schmid, H | 1 |
| Weiss, M | 1 |
| Dendorfer, U | 1 |
| Braun, GS | 1 |
| Ajayi, AA | 1 |
| Adigun, AQ | 1 |
| Mono, G | 1 |
| Kuhn, E | 1 |
| Friedman, G | 1 |
| Stein, O | 1 |
| Halperin, G | 1 |
| Kimchi, A | 1 |
| Stein, Y | 1 |
| Hauss, WH | 1 |
| Mey, J | 1 |
| Schulte, H | 1 |
| Seligman, SJ | 1 |
| Choa, MS | 1 |
2 reviews available for chloroquine and Hypertension
| Article | Year |
|---|---|
The Effect of Coronavirus Disease 2019 on Cardiovascular Diseases.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Antirheumatic Agents; An | 2020 |
[Cardiotoxic effects of drugs and various other substances. A review].
Topics: Adrenergic Agonists; Amphetamine; Antimony; Arrhythmias, Cardiac; Arsenic Poisoning; Catecholamines; | 1978 |
12 other studies available for chloroquine and Hypertension
| Article | Year |
|---|---|
Autophagy plays a critical role in Klotho gene deficiency-induced arterial stiffening and hypertension.
Topics: Animals; Autophagy; Basic Helix-Loop-Helix Transcription Factors; Beclin-1; Blood Pressure; Chloroqu | 2019 |
Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application.
Topics: Animals; Autophagy; Cell Proliferation; Chloroquine; Hypertension; Lamin Type A; Male; Membrane Prot | 2021 |
Gender differences in treatment of Coronavirus Disease-2019.
Topics: Adenosine Monophosphate; Adult; Aged; Alanine; Amides; Antimalarials; Antiviral Agents; Cardiovascul | 2020 |
Does Malaria Cause Hypertension?
Topics: Antimalarials; Chloroquine; Drug Resistance; Humans; Hypertension; Malaria; Malaria, Falciparum | 2016 |
Chloroquine Suppresses the Development of Hypertension in Spontaneously Hypertensive Rats.
Topics: Animals; Blood Pressure; Blotting, Western; Chloroquine; Disease Models, Animal; Disease Progression | 2017 |
Autoimmune therapeutic chloroquine lowers blood pressure and improves endothelial function in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Autoimmune Diseases; Blood Pressure; Chloroquine; E | 2016 |
Toll-Like Receptors, Hypertension, and an Antimalarial Drug.
Topics: Animals; Antimalarials; Chloroquine; Hypertension; Rats; Rats, Inbred SHR; Toll-Like Receptors | 2017 |
Chloroquine-induced phospholipidosis of the kidney mimicking Fabry's disease: case report and review of the literature.
Topics: alpha-Galactosidase; Chloroquine; Diagnosis, Differential; Fabry Disease; Female; Humans; Hypertensi | 2003 |
Syncope following oral chloroquine administration in a hypertensive patient controlled on amlodipine.
Topics: Administration, Oral; Amlodipine; Chloroquine; Drug Synergism; Humans; Hypertension; Malaria; Male; | 2002 |
Study of cultured skin fibroblasts from patients with and without ischemic heart disease. Metabolism of low density lipoprotein and cholesterol ester, synthesis of cellular lipids and effect of chloroquine on accumulation of cholesterol ester.
Topics: Adult; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Coronary Disease; Fibroblasts; | 1978 |
Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells.
Topics: Animals; Aorta; Arteriosclerosis; Aspirin; Cell Division; Cells, Cultured; Chloroquine; Diabetes Mel | 1979 |
Transfusion-induced falciparum malaria.
Topics: Administration, Oral; Adult; Blood Donors; Carrier State; Chloroquine; Humans; Hypertension; Hyperth | 1971 |