Page last updated: 2024-10-26

diphenhydramine and Hypertension

diphenhydramine has been researched along with Hypertension in 17 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"A case of angioedema induced by antihypertensive therapy with lisinopril is presented."8.78Angioedema complicating lisinopril therapy. ( Nzerue, MC, 1992)
"A case of angioedema induced by antihypertensive therapy with lisinopril is presented."4.78Angioedema complicating lisinopril therapy. ( Nzerue, MC, 1992)
" A variety of adverse events (AEs) of varying severity have been noted during HPC infusions."1.40Infusion technique of hematopoietic progenitor cells and related adverse events (CME). ( Bryant, SC; Gastineau, DA; Greiner, CW; Hogan, WJ; Jacob, EK; Lingineni, RK; Mohr, A; Mulay, SB; Padley, D, 2014)
"Amantadine hydrochloride is an antiviral medication used as therapy for parkinsonism and as a cognitive enhancer."1.35Cardiotoxicity after massive amantadine overdose. ( Kazzi, Z; Morgan, B; Patel, M; Schwartz, M, 2008)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's3 (17.65)18.2507
2000's4 (23.53)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Qutob, HMH1
Saad, RA1
Bali, H1
Osailan, A1
Jaber, J1
Alzahrani, E1
Alyami, J1
Elsayed, H1
Alserihi, R1
Shaikhomar, OA1
Divya, KM1
Savitha, DP1
Krishna, GA1
Dhanya, TM1
Mohanan, PV1
Shah, SF1
Jafry, AT1
Hussain, G1
Kazim, AH1
Ali, M1
Rivani, E1
Endraswari, PD1
Widodo, ADW1
Khalil, MR1
Guldberg, R1
Nørgård, BM1
Uldbjerg, N1
Wehberg, S1
Fowobaje, KR1
Mashood, LO1
Ekholuenetale, M1
Ibidoja, OJ1
Romagnoli, A1
D'Agostino, M1
Pavoni, E1
Ardiccioni, C1
Motta, S1
Crippa, P1
Biagetti, G1
Notarstefano, V1
Rexha, J1
Perta, N1
Barocci, S1
Costabile, BK1
Colasurdo, G1
Caucci, S1
Mencarelli, D1
Turchetti, C1
Farina, M1
Pierantoni, L1
La Teana, A1
Al Hadi, R1
Cicconardi, F1
Chinappi, M1
Trucchi, E1
Mancia, F1
Menzo, S1
Morozzo Della Rocca, B1
D'Annessa, I1
Di Marino, D1
Choya, A1
de Rivas, B1
Gutiérrez-Ortiz, JI1
López-Fonseca, R1
Xu, S1
Cheng, B1
Huang, Z1
Liu, T1
Li, Y1
Jiang, L1
Guo, W1
Xiong, J1
Amirazodi, M1
Daryanoosh, F1
Mehrabi, A1
Gaeini, A1
Koushkie Jahromi, M1
Salesi, M1
Zarifkar, AH1
Studeny, P1
Netukova, M1
Nemcokova, M1
Klimesova, YM1
Krizova, D1
Kang, H1
Tao, Y1
Zhang, Q1
Sha, D1
Chen, Y1
Yao, J1
Gao, Y1
Liu, J1
Ji, L1
Shi, P1
Shi, C1
Wu, YL1
Wright, AI1
M El-Metwaly, N1
A Katouah, H1
El-Desouky, MG1
El-Bindary, AA1
El-Bindary, MA1
Kostakis, ID1
Raptis, DA1
Davidson, BR1
Iype, S1
Nasralla, D1
Imber, C1
Sharma, D1
Pissanou, T1
Pollok, JM1
Hughes, AM1
Sanderson, E1
Morris, T1
Ayorech, Z1
Tesli, M1
Ask, H1
Reichborn-Kjennerud, T1
Andreassen, OA1
Magnus, P1
Helgeland, Ø1
Johansson, S1
Njølstad, P1
Davey Smith, G1
Havdahl, A1
Howe, LD1
Davies, NM1
Amrillah, T1
Prasetio, A1
Supandi, AR1
Sidiq, DH1
Putra, FS1
Nugroho, MA1
Salsabilla, Z1
Azmi, R1
Grammatikopoulos, P1
Bouloumis, T1
Steinhauer, S1
Mironov, VS2
Bazhenova, TA2
Manakin, YV2
Yagubskii, EB2
Yakushev, IA1
Gilmutdinov, IF1
Simonov, SV1
Lan, K1
Yang, H1
Zheng, J1
Hu, H1
Zhu, T1
Zou, X1
Hu, B1
Liu, H1
Olokede, O1
Wu, H1
Holtzapple, M1
Gungor, O1
Kose, M1
Ghaemi, R1
Acker, M1
Stosic, A1
Jacobs, R1
Selvaganapathy, PR1
Ludwig, N1
Yerneni, SS1
Azambuja, JH1
Pietrowska, M1
Widłak, P1
Hinck, CS1
Głuszko, A1
Szczepański, MJ1
Kärmer, T1
Kallinger, I1
Schulz, D1
Bauer, RJ1
Spanier, G1
Spoerl, S1
Meier, JK1
Ettl, T1
Razzo, BM1
Reichert, TE1
Hinck, AP1
Whiteside, TL1
Wei, ZL1
Juan, W1
Tong, D1
Juan, LX1
Sa, LY1
Jie, HFM1
Xiao, G1
Xiang, LG1
Jie, HM1
Xu, C1
Yu, DN1
Yao, ZX1
Bigdeli, F1
Gao, XM1
Cheng, X1
Li, JZ1
Zhang, JW1
Wang, W2
Guan, ZJ1
Bu, Y1
Liu, KG1
Morsali, A1
Das, R1
Paul, R1
Parui, A1
Shrotri, A1
Atzori, C1
Lomachenko, KA1
Singh, AK1
Mondal, J1
Peter, SC1
Florimbio, AR1
Coughlin, LN1
Bauermeister, JA1
Young, SD1
Zimmerman, MA1
Walton, MA1
Bonar, EE1
Demir, D1
Balci, AB1
Kahraman, N1
Sunbul, SA1
Gucu, A1
Seker, IB1
Badem, S1
Yuksel, A1
Ozyazicioglu, AF1
Goncu, MT1
Zhang, H1
Zhou, H1
Deng, Z1
Luo, L1
Ong, SP1
Wang, C1
Xin, H1
Whittingham, MS1
Zhou, G1
Maemura, R1
Wakamatsu, M1
Matsumoto, K1
Sakaguchi, H1
Yoshida, N1
Hama, A1
Yoshida, T1
Miwata, S1
Kitazawa, H1
Narita, K1
Kataoka, S1
Ichikawa, D1
Hamada, M1
Taniguchi, R1
Suzuki, K1
Kawashima, N1
Nishikawa, E1
Narita, A1
Okuno, Y1
Nishio, N1
Kato, K1
Kojima, S1
Morita, K1
Muramatsu, H1
Takahashi, Y1
Yirgu, A1
Mekonnen, Y1
Eyado, A1
Staropoli, A1
Vinale, F1
Zac, J1
Zac, S1
Pérez-Padilla, R1
Remigio-Luna, A1
Guzmán-Boulloud, N1
Gochicoa-Rangel, L1
Guzmán-Valderrábano, C1
Thirión-Romero, I1
Statsenko, ME1
Turkina, SV1
Barantsevich, ER1
Karakulova, YV1
Baranova, NS1
Morzhukhina, MV1
Wang, Q1
Gu, Y1
Chen, C1
Qiao, L1
Pan, F1
Song, C1
Canetto, SS1
Entilli, L1
Cerbo, I1
Cipolletta, S1
Wu, Y2
Zhu, P1
Jiang, Y1
Zhang, X1
Wang, Z1
Xie, B1
Song, T1
Zhang, F1
Luo, A1
Li, S1
Xiong, X1
Han, J1
Peng, X1
Li, M1
Huang, L1
Chen, Q1
Fang, W1
Hou, Y1
Zhu, Y1
Ye, J1
Liu, L1
Islam, MR1
Sanderson, P1
Johansen, MP1
Payne, TE1
Naidu, R1
Cao, J1
Yang, J1
Niu, X1
Liu, X1
Zhai, Y1
Qiang, C1
Niu, Y1
Li, Z1
Dong, N1
Wen, B1
Ouyang, Z1
Zhang, Y1
Li, J2
Zhao, M1
Zhao, J1
Morici, P1
Rizzato, C1
Ghelardi, E1
Rossolini, GM1
Lupetti, A1
Gözüküçük, R1
Cakiroglu, B1
He, X1
Li, R1
Zhao, D1
Zhang, L1
Ji, X1
Fan, X1
Chen, J1
Wang, Y1
Luo, Y1
Zheng, D1
Xie, L1
Sun, S1
Cai, Z1
Liu, Q1
Ma, K1
Sun, X1
Drinkwater, JJ1
Davis, TME1
Turner, AW1
Davis, WA1
Suzuki, Y1
Mizuta, Y1
Mikagi, A1
Misawa-Suzuki, T1
Tsuchido, Y1
Sugaya, T1
Hashimoto, T1
Ema, K1
Hayashita, T1
Mulay, SB1
Greiner, CW1
Mohr, A1
Bryant, SC1
Lingineni, RK1
Padley, D1
Hogan, WJ1
Gastineau, DA1
Jacob, EK1
Schwartz, M1
Patel, M1
Kazzi, Z1
Morgan, B1
Fridman, V1
Galetta, SL1
Pruitt, AA1
Levine, JM1
KALAS, JP1
JACOBSON, ED1
Hannaway, PJ1
Bottenberg, MM1
Wall, GC1
Hicklin, GA1
Derbez, R1
Grauer, H1
Altorfer, R1
Roscoe, AK1
Leach, SM1
Nyce, JW1
Wooles, WR1
García Rodríguez, M1
Nzerue, MC1
Gianos, ME1
Klaustermeyer, WB1
Kurohara, M1
Tarnasky, P1
Gordon, E1
Tanaka, K1
Lin, Y1
Foldes, FF1
Claman, HN1
Karr, RM1
Kohler, PF1
Mass, MF1
McIntosh, RM1
Sams, WM1
Small, P1
Stanford, RE1
Thorne, EG1
Hilton, JG1

Reviews

3 reviews available for diphenhydramine and Hypertension

ArticleYear
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
Angioedema complicating lisinopril therapy.
    The Central African journal of medicine, 1992, Volume: 38, Issue:9

    Topics: Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Diphenhydramine; Female; Hum

1992
Neuroleptanesthesia for general surgery.
    International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3

    Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hyperte

1973

Trials

2 trials available for diphenhydramine and Hypertension

ArticleYear
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
    Medicina clinica (English ed.), 2022, Dec-23, Volume: 159, Issue:12

    Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter

2022
A sleep study and investigation of a new hypnotic compound in a geriatric population.
    Canadian Medical Association journal, 1967, Dec-02, Volume: 97, Issue:23

    Topics: Aged; Arteriosclerosis; Bronchitis; Chronic Disease; Diabetes Complications; Diphenhydramine; Female

1967

Other Studies

13 other studies available for diphenhydramine and Hypertension

ArticleYear
Infusion technique of hematopoietic progenitor cells and related adverse events (CME).
    Transfusion, 2014, Volume: 54, Issue:8

    Topics: Acetaminophen; Adolescent; Adult; Aged; Blood Preservation; Child; Child, Preschool; Cryopreservatio

2014
Cardiotoxicity after massive amantadine overdose.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:3

    Topics: Adult; Amantadine; Antiparkinson Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; C

2008
MRI findings associated with acute liver failure.
    Neurology, 2009, Jun-16, Volume: 72, Issue:24

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain; Brain Edema; Coma; Diphenhydramine; Hepatic E

2009
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
    American heart journal, 1964, Volume: 67

    Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr

1964
Emergency department treatment of anaphylaxis: is epinephrine always indicated?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:1

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Contraindications; Diphenhyd

2006
Apparent anaphylactoid reaction after treatment with a single dose of telithromycin.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2007, Volume: 98, Issue:1

    Topics: Adrenal Cortex Hormones; Anaphylaxis; Anti-Allergic Agents; Anti-Bacterial Agents; Azithromycin; Bro

2007
[Diphenhydramine poisoning (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1981, Apr-14, Volume: 70, Issue:16

    Topics: Adolescent; Adult; Antidotes; Diphenhydramine; Female; Humans; Hypertension; Male; Psychoses, Substa

1981
Hypotensive effects of [D-Tyr27,36, D-Thr32]Neuropeptide Y (27-36).
    Peptides, 1995, Volume: 16, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug;

1995
[Antagonism of guanethidine action and the others blocking agents by diphenychydramine, imipramine and dextroamphetamine in illation with human hypertension (author's transl)].
    Archivos de farmacologia y toxicologia, 1975, Volume: 1, Issue:3

    Topics: Animals; Dextroamphetamine; Diphenhydramine; Guanethidine; Hypertension; Imipramine; Male; Rats; Sti

1975
Enalapril induced angioedema.
    The American journal of emergency medicine, 1990, Volume: 8, Issue:2

    Topics: Aged; Airway Obstruction; Angioedema; Diphenhydramine; Enalapril; Humans; Hypertension; Male; Middle

1990
Histamine liberation into the cerebrospinal fluid by the drugs applied intraventricularly.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:4

    Topics: Alkaloids; Animals; Blood Pressure; Cerebral Ventricles; Diphenhydramine; Histamine; Histamine Relea

1969
Systemic (allergic?) vasculitis.
    The Journal of allergy and clinical immunology, 1974, Volume: 54, Issue:1

    Topics: Antigen-Antibody Complex; Azathioprine; Complement System Proteins; Creatinine; Diphenhydramine; Ery

1974
Effect of various drugs upon the neostigmine pressor response.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 171, Issue:1

    Topics: Acetylcholine; Animals; Benzene Derivatives; Blood Pressure; Chlorisondamine; Diphenhydramine; Dogs;

1968