neostigmine has been researched along with Hypertension in 26 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response curve for the stimulating effect of neostigmine on saliva production was shifted to the right in borderline hypertensive as compared with normotensive subjects." | 2.65 | Studies of salivary flow in borderline hypertension: effects of drugs acting on structures innervated by the autonomic nervous system. ( Rahn, KH; Schols, M; van Baak, MA; van Hooff, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (80.77) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubost, C | 1 |
| de Saint Maurice, G | 1 |
| Vichard, A | 1 |
| Berbari, H | 1 |
| Lenoir, B | 1 |
| Chau, WH | 1 |
| Lee, WH | 1 |
| Lau, WH | 1 |
| Kwan, YW | 1 |
| Au, AL | 1 |
| Raymond, K | 1 |
| Thomas, MC | 1 |
| Erstad, BL | 1 |
| VON EICKSTEDT, KW | 1 |
| ERDMANN, WD | 1 |
| SCHAEFER, KP | 1 |
| SAYIL, TA | 1 |
| FISCHER, P | 1 |
| ROTHE, K | 1 |
| WEISSBRODT, C | 1 |
| GOUGNARD, L | 1 |
| SERRANO MOLINA, J | 1 |
| BAUER, GE | 1 |
| BOGAERT, M | 1 |
| DESCHAEPDRYVER, AF | 1 |
| Baggot, MG | 1 |
| Seidl, DC | 1 |
| Martin, DE | 1 |
| van Hooff, M | 2 |
| van Baak, MA | 1 |
| Schols, M | 1 |
| Rahn, KH | 2 |
| Volpe, M | 3 |
| Trimarco, B | 3 |
| Ricciardelli, B | 3 |
| Vigorito, C | 3 |
| de Luca, N | 1 |
| Rengo, F | 3 |
| Condorelli, M | 3 |
| Sacca, L | 1 |
| D'Ascia, C | 1 |
| De Simone, A | 1 |
| Buccafusco, JJ | 2 |
| Magri, V | 2 |
| Böhm, R | 1 |
| van Baak, M | 1 |
| Moy, J | 1 |
| Meiring, PD | 1 |
| Komesaroff, D | 1 |
| Field, JE | 1 |
| List, WF | 1 |
| Zahn, K | 1 |
| Rossier, AB | 2 |
| Ziegler, WH | 2 |
| Duchosal, PW | 2 |
| Meylan, J | 2 |
| Hilton, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized Trial of Enteral Naloxone Versus a Traditional Bowel Regimen in Prevention of Constipation and Decreased Gastric Motility in Critically Ill Trauma Patients[NCT00799201] | Phase 4 | 3 participants (Actual) | Interventional | 2007-08-31 | Terminated (stopped due to Naloxone became unavailable due to manufacturing shortatges requiring the study to be terminated.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for neostigmine and Hypertension
| Article | Year |
|---|---|
[Cardiac arrhythmias during anesthesia: their origin and pharmacological control].
Topics: Anesthetics; Arrhythmias, Cardiac; Catecholamines; Digitalis Glycosides; Electroshock; Heart Disease | 1966 |
3 trials available for neostigmine and Hypertension
| Article | Year |
|---|---|
Safety of enteral naloxone and i.v. neostigmine when used to relieve constipation.
Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Colic; | 2003 |
Studies of salivary flow in borderline hypertension: effects of drugs acting on structures innervated by the autonomic nervous system.
Topics: Adult; Atropine; Autonomic Agents; Autonomic Nervous System; Blood Pressure; Heart Rate; Humans; Hyp | 1984 |
The autonomic nervous tone abnormalities in the genesis of the impaired baroreflex responsiveness in borderline hypertensive subjects.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Neostigmine; Phenylephrine; P | 1982 |
22 other studies available for neostigmine and Hypertension
| Article | Year |
|---|---|
Right to the heart: a case of accidental phenylephrine intoxication.
Topics: Adult; Cholecystectomy, Laparoscopic; Humans; Hypertension; Injections, Intravenous; Male; Medicatio | 2011 |
Role of Na+/H+ exchanger in acetylcholine-mediated pulmonary artery contraction of spontaneously hypertensive rats.
Topics: Acetylcholine; Amiloride; Animals; Calcium; Cholinesterase Inhibitors; Dose-Response Relationship, D | 2003 |
[Hypertensive effect of esterase inhibitors, E 605, eserine and prostigmine].
Topics: Blood Pressure; Blood Pressure Determination; Esterases; Humans; Hypertension; Neostigmine; Parathio | 1955 |
[Hypotensen therapy of hypertension].
Topics: Cardiovascular Agents; Hydralazine; Hypertension; Muscle Relaxants, Central; Neostigmine; Reserpine | 1957 |
[Effect of a vagomimetic in combination with a new ganglion blocking agent in treatment of hypertension].
Topics: Autonomic Agents; Ganglionic Blockers; Hypertension; Neostigmine | 1957 |
[Treatment of intraocular hypertension with bromide salt of BC 48].
Topics: Bromides; Glaucoma; Hypertension; Neostigmine | 1957 |
[Pharmacological trials on the everted guinea pig intestine].
Topics: Amine Oxidase (Copper-Containing); Arginine Vasopressin; Bradykinin; Guinea Pigs; Hypertension; Inte | 1962 |
BUNDLE-BRANCH BLOCK UNDER VOLUNTARY CONTROL.
Topics: Atropine; Bundle-Branch Block; Cardiac Conduction System Disease; Cardiomegaly; Carotid Sinus; Diagn | 1964 |
ADRENERGIC MECHANISMS IN THE DOG HEART.
Topics: Acetylcholine; Adrenergic Agents; Atropine; Carotid Sinus; Cholinesterase Inhibitors; Cholinesterase | 1964 |
Endo-abdominal hypertension complicating pregnancy & fetal development.
Topics: Abdomen; Female; Fetal Development; Humans; Hypertension; Ileus; Male; Neostigmine; Obesity; Parasym | 2006 |
Prolonged bradycardia after neostigmine administration in a patient taking nadolol.
Topics: Anesthesia, General; Bradycardia; Drug Interactions; Female; Humans; Hypertension; Middle Aged; Nado | 1984 |
Baroreflex responsiveness in borderline hypertensives: a study with neostigmine.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Neostigmine; Par | 1981 |
[Preliminary study of the cardiovascular effect of neostigmine in "borderline" arterial hypertension].
Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Neostigmine | 1980 |
The pressor response to spinal cholinergic stimulation in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Carbachol; Electric Stimulation; Heart Rate; Hemicholinium 3 | 1990 |
Hypertension following intrathecal injection of cholinergic agonists in conscious rats: role of endogenous acetylcholine.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Cholinergic Fibers; Hemicholinium 3; Hypert | 1988 |
Salivary flow in borderline hypertension.
Topics: Adult; Atropine; Humans; Hypertension; Male; Neostigmine; Norepinephrine; Phentolamine; Potassium; P | 1985 |
Association between hypothyroidism and myasthenia gravis and a concept of generalized systemic auto-immunopathy.
Topics: Autoimmune Diseases; Beta-Globulins; Female; gamma-Globulins; Humans; Hypertension; Hypothyroidism; | 1967 |
Pancuronium bromide: a new non-depolarizing muscle relaxant.
Topics: Androstanes; Atropine; Body Weight; Histamine Release; Humans; Hypertension; Hypothermia, Induced; I | 1969 |
The effects of vasoactive drugs on the retinal circulation.
Topics: Bis-Trimethylammonium Compounds; Bromides; Ergoloid Mesylates; Heparin; Hydralazine; Hypertension; N | 1966 |
Sexual function and dysreflexia.
Topics: Accidents, Traffic; Adult; Arrhythmias, Cardiac; Blood Pressure; Catecholamines; Dysautonomia, Famil | 1971 |
[Sexual function, autonomic dysreflexia and catecholamines in traumatic medullary lesions].
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure Determination; Catecholamines; Dysautonomia, Familial; E | 1971 |
Effect of various drugs upon the neostigmine pressor response.
Topics: Acetylcholine; Animals; Benzene Derivatives; Blood Pressure; Chlorisondamine; Diphenhydramine; Dogs; | 1968 |