pilocarpine has been researched along with Hypertension in 16 studies
Pilocarpine: A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
(+)-pilocarpine : The (+)-enantiomer of pilocarpine.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension." | 7.74 | Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake. ( Borella, TL; Colombari, DS; De Luca, LA; Menani, JV, 2008) |
| "Recent evidence has suggested that pilocarpine (ACh receptor agonist) injected peripherally may act centrally producing salivation and hypertension." | 3.74 | Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake. ( Borella, TL; Colombari, DS; De Luca, LA; Menani, JV, 2008) |
| "2 yrs) (d) subjects who were not diabetic or exposed to vibrating tools, but were being treated with the ACE-inhibitor enalapril 20 mg daily for hypertension (n = 5, mean age 54 yrs) (e) subjects who had smoked more than 10 cigarettes daily for at least 15 yrs (n = 10, mean age 51 yrs)." | 3.68 | Confounding factors in non-invasive tests of neurovascular function in diabetes mellitus. ( Delaney, CA; Lindblad, LE; Roberts, RG; Wajnblum, D; Westerman, RA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JY | 1 |
| Chew, KS | 1 |
| Mary, S | 1 |
| Boder, P | 1 |
| Bagordo, D | 1 |
| Rossi, GP | 1 |
| Touyz, RM | 1 |
| Delles, C | 1 |
| Rossitto, G | 1 |
| Chen, YY | 1 |
| Lai, YJ | 1 |
| Yen, YF | 1 |
| Shen, YC | 1 |
| Wang, CY | 1 |
| Liang, CY | 1 |
| Lin, KH | 1 |
| Fan, LW | 1 |
| Gharbiya, M | 1 |
| Colica, C | 1 |
| Campagna, O | 1 |
| De Vico, U | 1 |
| Cruciani, F | 1 |
| Borella, TL | 1 |
| De Luca, LA | 1 |
| Colombari, DS | 1 |
| Menani, JV | 1 |
| GUNN, JA | 1 |
| COOKE, AM | 1 |
| Scorza, FA | 1 |
| Arida, RM | 1 |
| Cysneiros, RM | 1 |
| Scorza, CA | 1 |
| de Albuquerque, M | 1 |
| Cavalheiro, EA | 1 |
| Mourad, JJ | 1 |
| des Guetz, G | 1 |
| Debbabi, H | 1 |
| Levy, BI | 1 |
| Norden, LC | 1 |
| Westerman, RA | 1 |
| Lindblad, LE | 1 |
| Wajnblum, D | 1 |
| Roberts, RG | 1 |
| Delaney, CA | 1 |
| Geyer, O | 1 |
| Loewenstein, A | 1 |
| Lazar, M | 1 |
| Finocchiaro, LM | 1 |
| Scheucher, A | 1 |
| Alvarez, AL | 1 |
| Finkielman, S | 1 |
| Nahmod, VE | 1 |
| Pirola, CJ | 1 |
| Martin, X | 1 |
| Kimura, K | 1 |
| Manor, RS | 1 |
| Sachs, W | 1 |
| Weekers, R | 1 |
| Muller, AF | 1 |
| Veyrat, R | 1 |
| Grandchamp, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Exploratory Study. Endothelial Function and Vascular Biomarkers: Predictive Indicators of the Progression From Gestational Hypertension to Preeclampsia?[NCT04520048] | 110 participants (Anticipated) | Interventional | 2023-08-24 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 other studies available for pilocarpine and Hypertension
| Article | Year |
|---|---|
Skin-specific mechanisms of body fluid regulation in hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhi | 2023 |
Association between normal tension glaucoma and the risk of Alzheimer's disease: a nationwide population-based cohort study in Taiwan.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Age Factors; Aged; Alzheimer Disease; Carbon | 2018 |
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resi | 2013 |
Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake.
Topics: Animals; Blood Pressure; Diamines; Drinking Behavior; Heart Rate; Hypertension; Injections, Intraven | 2008 |
Pilocarpine as an antagonist to the undesired effects of ganglion-blocking agents in the treatment of hypertension.
Topics: Autonomic Agents; Ganglionic Blockers; Hypertension; Musculoskeletal Physiological Phenomena; Piloca | 1954 |
[Qualitative study of hippocampal formation in hypertensive rats with epilepsy].
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy; Hippocampus; Hypertension; Male; Neurons; | 2005 |
Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation.
Topics: Adenocarcinoma; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Human | 2008 |
Adverse reactions to topical ocular autonomic agents.
Topics: Atropine; Autonomic Agents; Corneal Diseases; Cyclopentolate; Drug Hypersensitivity; Glaucoma; Human | 1978 |
Confounding factors in non-invasive tests of neurovascular function in diabetes mellitus.
Topics: Acetylcholine; Axons; Blood Vessels; Diabetes Mellitus; Enalapril; Humans; Hypertension; Male; Middl | 1992 |
Glaucoma masked by systemic medications.
Topics: Antihypertensive Agents; Glaucoma; Humans; Hypertension; Male; Middle Aged; Pilocarpine | 1991 |
Pineal hyperactivity in spontaneously hypertensive rats: muscarinic regulation of indole metabolism.
Topics: Animals; Electric Stimulation; Hypertension; Indoles; Male; Melatonin; Parasympathetic Nervous Syste | 1990 |
[Local cholinergic agonists and paradoxal systemic reactions].
Topics: Acetylcholine; Aged; Blood Pressure; Drug Hypersensitivity; Female; Humans; Hypertension; Male; Para | 1987 |
Pathophsiological significance of sympathetic activity in cardiovascular diseases.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Coronar | 1974 |
Spontaneous hyphema.
Topics: Anterior Chamber; Eye Diseases; Female; Follow-Up Studies; Humans; Hypertension; Hyphema; Middle Age | 1972 |
[The treatment of narrow-angle glaucoma].
Topics: Carbonic Anhydrase Inhibitors; Diathermy; Epinephrine; Glaucoma; Hypertension; Pilocarpine | 1968 |
[Hypokalemia].
Topics: Adolescent; Adult; Cathartics; Child; Diagnosis, Differential; Diuretics; Female; Humans; Hyperaldos | 1968 |