Assay ID | Title | Year | Journal | Article |
AID192915 | % decrease in heart 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 75 mg/kg dose perorally; value significantly different was control | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192907 | % decrease in adrenal epinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 35 mg/kg dose perorally; NA is not available | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193707 | % decrease in hypothalamus norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 4 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193708 | % decrease in hypothalamus norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 75 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192916 | % decrease in heart 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 8 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192921 | % decrease in hypothalamus dopamine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 8 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192436 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 17 mg/kg dose, perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193568 | % decrease in hypothalamus norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 17.5 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193556 | % decrease in heart norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 75 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193555 | % decrease in heart norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 4 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192442 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 4 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193709 | % decrease in hypothalamus norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 8 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192914 | % decrease in heart 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 4 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192917 | % decrease in hypothalamus 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID174082 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) at 7.5 hours after administration of 17 mg/kg dose, perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192908 | % decrease in adrenal epinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 4 mg/kg dose perorally; NA is not available | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192441 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193553 | % decrease in heart norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 17.5 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192920 | % decrease in hypothalamus dopamine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 4 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192906 | % decrease in adrenal epinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 17.5 mg/kg dose perorally; NA is not available | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192913 | % decrease in heart 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 35 mg/kg dose perorally; value significantly different was control | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192911 | % decrease in heart 5-HT in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 17.5 mg/kg dose perorally; value significantly different was control | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192445 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 75 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192918 | % decrease in hypothalamus dopamine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 75 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID174085 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) at 7.5 hours after administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192919 | % decrease in hypothalamus dopamine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 17.5 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192444 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats (SHR) before administration of 75 mg/kg dose perorally. | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192446 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 8 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193557 | % decrease in heart norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 8 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192440 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID174220 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) at 7.5 hours after administration of 75 mg/kg dose intravenously | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193554 | % decrease in heart norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID41752 | Inhibition constant from beta adrenergic receptor binding assay | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192909 | % decrease in adrenal epinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 75 mg/kg dose perorally; NA is not available | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID193569 | % decrease in hypothalamus norepinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 35 mg/kg dose perorally | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192437 | Systolic blood pressure (SBP) in anesthetized spontaneously hypertensive rats(SHR) before administration of 17.5 mg/kg dose perorally; data statistically significant | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID223040 | Inhibition of the isoproterenol response at a dose of 1 x 10e -4M in guinea pig; slight inhibition was found | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
AID192910 | % decrease in adrenal epinephrine in anesthetized spontaneously hypertensive rats(SHR) at 5 hours after administration of 8 mg/kg dose perorally; NA is not available | 1989 | Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
| Flavones. 2. Synthesis and structure-activity relationship of flavodilol and its analogues, a novel class of antihypertensive agents with catecholamine depleting properties. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |