spiperone has been researched along with Hypertension in 10 studies
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chronic administration of cyclo(leucyl-glycine), an analog derived from the hypothalamic peptide, melanotropin release inhibiting factor, decreased the enhanced number of [3H]spiroperidol binding sites in the striatum and hypothalamus of the hypertensive rats." | 1.27 | Effect of cyclo(leucyl-glycine) on [3H]spiroperidol binding in the corpus striatum and hypothalamus of spontaneously hypertensive rats. ( Bhargava, HN, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hellstrand, K | 1 |
| Engel, J | 1 |
| Rosenblatt, JE | 1 |
| Shore, D | 1 |
| Wyatt, RJ | 1 |
| Pert, CB | 1 |
| Chiu, P | 2 |
| Rajakumar, G | 2 |
| Chiu, S | 2 |
| Kwan, CY | 2 |
| Mishra, RK | 2 |
| Le Fur, G | 1 |
| Guilloux, F | 1 |
| Uzan, A | 1 |
| Bhargava, HN | 1 |
| Watanabe, Y | 1 |
| Fujita, M | 1 |
| Ito, Y | 1 |
| Okada, T | 1 |
| Kusuoka, H | 1 |
| Nishimura, T | 1 |
| Barili, P | 1 |
| Fringuelli, C | 1 |
| Baldoni, E | 1 |
| Mignini, F | 1 |
| Zaccheo, D | 1 |
| Amenta, F | 1 |
| Kujirai, K | 1 |
| Przedborski, S | 1 |
| Kostic, V | 1 |
| Jackson-Lewis, V | 1 |
| Fahn, S | 1 |
| Cadet, JL | 1 |
| Watanabe, M | 1 |
| Tsuruta, S | 1 |
| Inoue, Y | 1 |
| Kinuya, M | 1 |
| Ogawa, K | 1 |
| Mamiya, G | 1 |
| Tatsunuma, T | 1 |
10 other studies available for spiperone and Hypertension
| Article | Year |
|---|---|
Locomotor activity and catecholamine receptor binding in adult normotensive and spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Brain Stem; Cerebral Cortex; Dioxanes; Hypertension; H | 1980 |
Increased renal neuroleptic binding in spontaneously hypertensive rats.
Topics: Animals; Antipsychotic Agents; Binding Sites; Brain; Hypertension; In Vitro Techniques; Kidney; Rats | 1980 |
Differential changes in central serotonin and dopamine receptors in spontaneous hypertensive rats.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Hippocampus; Hypertension; Limbic System; Male; Mesenceph | 1984 |
Evidence for an increase in [3H]spiperone binding in hypothalamic nuclei during the development of spontaneous hypertension in the rat.
Topics: Animals; Blood Pressure; Butyrophenones; Dopamine; Hypertension; Hypothalamus; Male; Neurons; Rats; | 1983 |
Effect of cyclo(leucyl-glycine) on [3H]spiroperidol binding in the corpus striatum and hypothalamus of spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Butyrophenones; Cell Membrane; Corpus Striatum; Dipeptides; Hypertension; Hy | 1984 |
Enhanced [3H]spiroperidol binding in striatum of spontaneously hypertensive rat (SHR).
Topics: Animals; Blood Pressure; Butyrophenones; Corpus Striatum; Hypertension; In Vitro Techniques; Male; R | 1982 |
Brain dopamine transporter in spontaneously hypertensive rats.
Topics: Animals; Autoradiography; Benzazepines; Binding Sites; Brain Chemistry; Carrier Proteins; Caudate Nu | 1997 |
Dopamine D2-like receptors in the kidney of spontaneously hypertensive rats: a radioligand binding assay and light microscope autoradiography study.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Binding, Competitive; Blood Pressure; Body Weig | 1998 |
Autoradiography of dopamine receptors and dopamine uptake sites in the spontaneously hypertensive rat.
Topics: Animals; Autoradiography; Benzazepines; Brain; Dopamine; Hydroxydopamines; Hypertension; Mazindol; O | 1990 |
Dopamine D1 and D2 receptors in spontaneously hypertensive rat brain striatum.
Topics: Animals; Benzazepines; Corpus Striatum; Hypertension; Kinetics; Male; Rats; Rats, Inbred SHR; Rats, | 1989 |